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FlySiesta: Analysis Suite for Drosophila Sleep and Activity Dynamics
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************************************************************************************** FlySiesta version 1.01 http://www.neural-circuits.org/flysiesta Copyright (C) 2007-2015 Amanda Sorribes, Universidad Autonoma de Madrid, and Consejo Superior de Investigaciones Cientificas (CSIC). For info on future releases, comments, bug reports, improvements or feature requests, please write to: [email protected] ************************************************************************************** Contents -------------------------- I. Brief Description II. Installation & Usage III. Requirements IV. Bug Reports & Improvements V. Acknowledgements VI. License I. Brief Description ------------------------------------------------------------------------- FlySiesta is a MATLAB based program that analyzes activity and sleep data of flies. The program has been tuned to read data files obtained with the Drosophila Activity Monitoring (DAM) System, by TriKinetics. Although the program extracts "general" activity parameters such as the activity and sleep profiles, the total time of activity/sleep, mean bout lengths and number of bouts - FlySiesta's main focus lies in analyzing the fine scale dynamics of the transitions between the behavioral states, by studying the 'burstiness' of the inter- event-interval or event-length distributions. For more information on how to interpret the burstiness parameters, see: A Sorribes, BG Armendariz, D Lopez-Pigozzi, C Murga & GG de Polavieja, The Origin of Behavioral Bursts in Decision-Making Circuitry PLoS Comp. Biol. 7(6): e1002075 (2011) II. Installation & Usage ------------------------------------------------------------------------- 1. Unzip the files. The files unzip into a folder named 'FlySiesta', which in turn has a subfolder named 'fsaux'. The FlySiesta folder can now be moved to any desired location (but keep the internal structure of the files and subfolders). 2. Open MATLAB, and browse to the FlySiesta folder. 3. Type "install_flysiesta" (without the quotes) in MATLAB. This will add the FlySiesta folder and subfolders to Matlab's path, so the program can be run from any location from now on. 4. Type "flysiesta" (lower-case, no quotes) to run the program. For help on using the program, see the FlySiesta User Guide, at http://www.neural-circuits.org/flysiesta/userguide III. Requirements ------------------------------------------------------------------------- Apart from Matlab, FlySiesta requires Matlab's Statistical Toolbox and Matlab's Curve Fitting Toolbox, to perform its analysis. IV. Bug Reports & Improvements ------------------------------------------------------------------------- FlySiesta version 1.01 has been written in Matlab, versions 2007b - 2012a on a Windows (XP, Vista and Windows 7 & 8) platforms. It is my hope that it will also work in newer (and maybe older) versions of Matlab, and on other platforms, but it has not been tested. If you encounter any bugs or error messages while using the program, please write me at: [email protected] If possible, please include the error message (the red message in the Matlab Command window), what you did when it occurred, which version of FlySiesta and of Matlab you are using, and the operating system. If you are proficient in Matlab programming and have made improvements to the code, please contact me and/or send me the code, so that we can incorporate it into the next release. Help in developing FlySiesta is gratefully received! V. Acknowledgements ------------------------------------------------------------------------- This program has been written by Amanda Sorribes, while in Gonzalo G. de Polavieja's Lab (Neural Processing Group) at the Universidad Autonoma de Madrid and (Systems Neuroscience Group) at the Cajal Institute, Consejo Superior de Investigaciones Cientificas, Spain. If you publish or present results that are based, or have made use of any part of the program, acknowledge FlySiesta and cite: A Sorribes, BG Armendariz, D Lopez-Pigozzi, C Murga, GG de Polavieja 'The Origin of Behavioral Bursts in Decision-Making Circuitry'. PLoS Comp. Biol. 7(6): e1002075 (2011) This program would not have been possible, without the support of the following research funding agencies: * Comunidad de Madrid - Programa Personal Investigador de Apoyo - Programa Biociencia * The European Social Fund * Universidad Autonoma de Madrid * Ministerio de Ciencia e Inovacion * Ministerio de Sanidad * The Cardiovascular Network RECAVA * Eranet SysBio+ I also want to especially thank Beatriz G. Armendariz, for testing, feedback and the endless patience during the development period, as well as Diego Lopez-Pigozzi. A special thanks to Enrique Turiegano and Alicia Gonzalo for testing the 'basic' version of the program and for all the positive input and support. Finally, I want to acknowledge the great icon set by Mark James, "Silk" (version 1.3), which you can get under Creative Commons Attribution 2.5 License, from http://www.famfamfam.com/lab/icons/silk and tabpanel version 2.6, (c) by Elmar Tarajan ([email protected]), which has been used with some modifications, in some of the FlySiesta subprograms. VI. License ------------------------------------------------------------------------- This program is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or any later version. This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with this program. If not, see <http://www.gnu.org/licenses/>.
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