A set of different models of human physiology in Modelica language using Physiolibrary. Includes supporting scripts for generating list of initial values.
Currently the circulation hemodynamic models are included based on description and literature made by
- Burkhoff et al.,
- Meurs et al.,
- Smith et al.,
- Fernandez et al.,
- Avolio,
- example of complex combined model by Kalecky.
This model set is a supplementary material to following articles:
- Lumped Models of the Cardiovascular System of Various Complexity by Filip Ježek, Tomáš Kulhánek, Karel Kalecký and Jiří Kofránek. DOI: 10.1016/j.bbe.2017.08.001
- T. Kulhánek and J. Kofránek, "Experience with Teaching Different Modeling Techniques on the example of Glucose Insulin Regulation Model," 2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Montreal, QC, Canada, 2020, pp. 6024-6027, doi: 10.1109/EMBC44109.2020.9176535
Download the library model and open in the following order:
- Physiolibrary/... from www.physiolibrary.org then for Cardiovascular
- Cardiovascular/package.mo for Metabolism
- Metabolism/package.mo
Run any model with a green Play triangle, e.g. Cardiovascular.Model.Meurs.HemodynamicsMeurs or Cardiovascular.Model.Complex.Cardio. With decomposed models, you can redeclare the submodels wby any other compatible submodel of same subsystem (in Dymola use right context menu - change class - all matching choices - select you choice).
You can watch an instructional video at [https://youtu.be/wcipWB1Ngnw]
The model library is available to the public use. Although the model library is implemented in the universal Modelica language, minor differences in interpretation persist among the various tools. The models has been developed and tested in the Dassault Systémes Dymola 2018 tool only. Other tools (Wolfram SystemModeler, OpenModelica etc) might be used as well, but we do not guarantee proper functionality.
Citable DOI https://doi.org/10.5281/zenodo.1098407