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remove unused param
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MikeWLloyd committed Jul 18, 2024
1 parent a3f717f commit 891c52f
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Showing 8 changed files with 9 additions and 13 deletions.
2 changes: 0 additions & 2 deletions bin/help/somatic_wes.nf
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Expand Up @@ -38,8 +38,6 @@ Parameter | Default | Description
--bait_picard | '/projects/omics_share/human/GRCh38/supporting_files/capture_kit_files/agilent/v7/S31285117_MergedProbes_no_gene_names.picard.interval_list' | A GATK interval file covering WES target intervals. Used in calculating coverage metrics. This file can be the same as the interval file, NOTE: This file MUST reflect the capture array used to generate your data.
--mismatch_penalty | -B 8 | The BWA penalty for a mismatch.
--call_val | 50 | The minimum phred-scaled confidence threshold at which variants should be called.
--ploidy_val | '-ploidy 2' | Sample ploidy
--gnomad_ref | '/projects/compsci/omics_share/human/GRCh38/genome/annotation/snps_indels/af-only-gnomad.hg38.vcf.gz' | GnomAD germline reference from GATK resource pack.
--pon_ref | '/projects/compsci/omics_share/human/GRCh38/genome/annotation/snps_indels/1000g_pon.hg38.vcf.gz' | 1000 genome germline panel of normals from GATK resource pack.
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2 changes: 0 additions & 2 deletions bin/help/somatic_wes_pta.nf
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Expand Up @@ -40,8 +40,6 @@ Parameter | Default | Description
--bait_picard | '/projects/omics_share/human/GRCh38/supporting_files/capture_kit_files/agilent/v7/S31285117_MergedProbes_no_gene_names.picard.interval_list' | A GATK interval file covering WES target intervals. Used in calculating coverage metrics. This file can be the same as the interval file, NOTE: This file MUST reflect the capture array used to generate your data.
--mismatch_penalty | -B 8 | The BWA penalty for a mismatch.
--call_val | 50 | The minimum phred-scaled confidence threshold at which variants should be called.
--ploidy_val | '-ploidy 2' | Sample ploidy
--gnomad_ref | '/projects/compsci/omics_share/human/GRCh38/genome/annotation/snps_indels/af-only-gnomad.hg38.vcf.gz' | GnomAD germline reference from GATK resource pack.
--pon_ref | '/projects/compsci/omics_share/human/GRCh38/genome/annotation/snps_indels/1000g_pon.hg38.vcf.gz' | 1000 genome germline panel of normals from GATK resource pack.
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1 change: 0 additions & 1 deletion bin/log/somatic_wes.nf
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Expand Up @@ -50,7 +50,6 @@ ______________________________________________________
--bait_picard ${params.bait_picard}
--snpEff_config ${params.snpEff_config}
--mismatch_penalty ${params.mismatch_penalty}
--call_val ${params.call_val}
--gen_ver ${params.gen_ver}
--gold_std_indels ${params.gold_std_indels}
--phase1_1000G ${params.phase1_1000G}
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1 change: 0 additions & 1 deletion bin/log/somatic_wes_pta.nf
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Expand Up @@ -47,7 +47,6 @@ ______________________________________________________
--bait_picard ${params.bait_picard}
--snpEff_config ${params.snpEff_config}
--mismatch_penalty ${params.mismatch_penalty}
--call_val ${params.call_val}
--gen_ver ${params.gen_ver}
--gold_std_indels ${params.gold_std_indels}
--phase1_1000G ${params.phase1_1000G}
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3 changes: 1 addition & 2 deletions config/somatic_wes.config
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Expand Up @@ -50,9 +50,8 @@ params {
target_picard = params.reference_cache+'/human/GRCh38/supporting_files/capture_kit_files/agilent/v7/S31285117_MergedProbes_no_gene_names.picard.interval_list'
bait_picard = params.reference_cache+'/human/GRCh38/supporting_files/capture_kit_files/agilent/v7/S31285117_MergedProbes_no_gene_names.picard.interval_list'

// Variant calling parameters
// BWA Param
mismatch_penalty = "-B 8"
call_val = "50.0"

gnomad_ref=params.reference_cache+'/human/GRCh38/genome/annotation/snps_indels/af-only-gnomad.hg38.vcf.gz'
pon_ref=params.reference_cache+'/human/GRCh38/genome/annotation/snps_indels/1000g_pon.hg38.vcf.gz'
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1 change: 0 additions & 1 deletion config/somatic_wes_pta.config
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Expand Up @@ -52,7 +52,6 @@ params {

// Variant calling parameters
mismatch_penalty = "-B 8"
call_val = "50.0"

gnomad_ref=params.reference_cache+'/human/GRCh38/genome/annotation/snps_indels/af-only-gnomad.hg38.vcf.gz'
pon_ref=params.reference_cache+'/human/GRCh38/genome/annotation/snps_indels/1000g_pon.hg38.vcf.gz'
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6 changes: 4 additions & 2 deletions config/wes.config
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Expand Up @@ -41,8 +41,9 @@ params {
target_picard = params.reference_cache+'/mouse/GRCm38/supporting_files/capture_kit_files/agilent/v2/S32371113_mouse_exon_V2.bare.picard.primary_assembly.interval_list'
bait_picard = params.reference_cache+'/mouse/GRCm38/supporting_files/capture_kit_files/agilent/v2/S32371113_mouse_exon_V2.bare.picard.primary_assembly.interval_list'

// Variant calling parameters
// BWA parameter
mismatch_penalty = "-B 8"
// Variant calling parameters
call_val = "50.0"
ploidy_val = "-ploidy 2"

Expand Down Expand Up @@ -75,8 +76,9 @@ if (params.gen_org=='human'){
params.target_picard = params.reference_cache+'/human/GRCh38/supporting_files/capture_kit_files/agilent/v7/S31285117_MergedProbes_no_gene_names.picard.interval_list'
params.bait_picard = params.reference_cache+'/human/GRCh38/supporting_files/capture_kit_files/agilent/v7/S31285117_MergedProbes_no_gene_names.picard.interval_list'

// Variant calling parameters
// BWA parameter
params.mismatch_penalty = "-B 8"
// Variant calling parameters
params.call_val = "50.0"
params.ploidy_val = "-ploidy 2"

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6 changes: 4 additions & 2 deletions config/wgs.config
Original file line number Diff line number Diff line change
Expand Up @@ -49,8 +49,9 @@ params {
dbSNP_index = params.reference_cache+'/mouse/GRCm38/genome/annotation/snps_indels/GCA_000001635.6_current_ids.vcf.gz.tbi'
snpEff_config = params.reference_cache+'/mouse/GRCm38/genome/indices/snpEff_5_1/snpEff.config'

// Variant calling parameters
// BWA parameter
mismatch_penalty = "-B 8"
// Variant calling parameters
ploidy_val = "-ploidy 2"
call_val = "50.0"

Expand All @@ -67,8 +68,9 @@ if (params.gen_org=='human'){
params.chrom_contigs = params.reference_cache+'/human/GRCh38/genome/sequence/gatk/Homo_sapiens_assembly38.primaryChr.contig_list'
params.primary_chrom_bed = params.reference_cache+'/human/GRCh38/genome/annotation/intervals/Homo_sapiens_assembly38.primary_chrom.bed'

// Variant calling parameters
// BWA parameter
params.mismatch_penalty = "-B 8"
// Variant calling parameters
params.ploidy_val = "-ploidy 2"
params.call_val = "50.0"

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