This is the repository for the paper titled "Protection from Killed Whole-Cell Cholera Vaccines: A Systematic Review and Meta-Analysis". This systematic review builds upon a previous systematic review by Bi et al. titled "Protection against cholera from killed whole-cell oral cholera vaccines: a systematic review and meta-analysis" published on Lancet Infectious Disease in 2017.
ve_meansvar.csv: this file contains data included in the previous search by Bi et al. 2017. Each estimate in this file represents the pooled estimate over the study's follow-up period without stratification by time since vaccination.FollowupPeriodData.csv: this file contains data included in the previous search by Bi et al. 2017. The estimates in this file are stratified by time since vaccination.extracted_SR_data_2017_2024.csv: contains data detected through new search.effectiveness_studies.csv,efficacy_studies.csv: contain meta-data of each included study in the current systematic review.propUnder5_data.csv: contains age-stratified information on each included study.QA_RCT_resolved.csv: contains the risk of bias assessment of all the included randomized clinical trials after resolving conflicts between two reviewers.
OCV_SR_update.Rmd: code used to conduct all the analyses and generation of tables and figures presented in the manuscript.panelPlot_colored.R,utils_OCV_SR.R: functions used in theOCV_SR_update.Rmd.