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choose test branches for relax selection #63

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xing-he529 opened this issue Nov 27, 2024 · 0 comments
Open

choose test branches for relax selection #63

xing-he529 opened this issue Nov 27, 2024 · 0 comments

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@xing-he529
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Dear HyPhy developers,
I am conducting a RELAX analysis using a phylogenetic tree with seven species. Among these, one species is particularly unique in its evolutionary context, and I aim to demonstrate that this species has experienced a higher proportion of genes under relaxed selection compared to the others.

To achieve this, I am considering treating each node in the tree as a test separately and performing the RELAX analysis for each. Then, I plan to compare the number of genes undergoing relaxation across the nodes to identify the species with the most relaxed genes.

Would this approach be appropriate for addressing my research question? Additionally, are there any specific considerations or alternative strategies you would recommend when using RELAX in this context?

Thank you for your guidance!

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