diff --git a/sa-index/src/bounds_table.rs b/sa-index/src/bounds_table.rs
new file mode 100644
index 0000000..c1ac418
--- /dev/null
+++ b/sa-index/src/bounds_table.rs
@@ -0,0 +1,88 @@
+pub struct BoundsCache<const K: u32> {
+    pub bounds: Vec<Option<(usize, usize)>>,
+
+    ascii_array: [usize; 128],
+    alphabet: Vec<u8>,
+    base: usize
+}
+
+impl<const K: u32> BoundsCache<K> {
+    pub fn new(alphabet: String) -> BoundsCache<K> {
+        let alphabet = alphabet.to_uppercase().as_bytes().to_vec();
+        let base = alphabet.len() + 1;
+
+        let mut ascii_array: [usize; 128] = [0; 128];
+        for (i, byte) in alphabet.iter().enumerate() {
+            // Add 1 to the index, so we can reserve a different value for the 0 index
+            ascii_array[*byte as usize] = i + 1;
+        }
+
+        BoundsCache {
+            bounds: vec![None; base.pow(K)],
+            ascii_array,
+            alphabet,
+            base
+        }
+    }
+
+    pub fn get_kmer(&self, kmer: &[u8]) -> Option<(usize, usize)> {
+        self.bounds.get(self.kmer_to_index(kmer)).cloned()?
+    }
+
+    pub fn update_all_kmers(&mut self, kmer: &[u8], bounds: (usize, usize)) {
+        let index = self.kmer_to_index(kmer);
+        self.bounds[index] = Some(bounds);
+    }
+
+    pub fn update_kmer(&mut self, kmer: &[u8], bounds: (usize, usize)) {
+        let index = self.kmer_to_index(kmer);
+        self.bounds[index] = Some(bounds);
+    }
+
+    pub fn index_to_kmer(&self, mut index: usize) -> Vec<u8> {
+        let mut kmer = Vec::with_capacity(K as usize);
+
+        for _ in 0..K {
+            let modulo = index % self.base;
+            if modulo == 0 {
+                return kmer.iter().rev().cloned().collect();
+            }
+            kmer.push(self.alphabet[modulo - 1]);
+
+            index /= self.base;
+        }
+
+        kmer.iter().rev().cloned().collect()
+    }
+
+    fn kmer_to_index(&self, kmer: &[u8]) -> usize {
+        kmer
+            .iter()
+            .rev()
+            .enumerate()
+            .map(|(i, n)| self.ascii_array[*n as usize] * self.base.pow(i as u32))
+            .sum()
+    }
+}
+
+#[cfg(test)]
+mod tests {
+    use super::*;
+
+    #[test]
+    fn test_bounds_cache() {
+        let kmer_cache = BoundsCache::<5>::new("ACDEFGHIKLMNPQRSTVWY".to_string());
+
+        assert_eq!(kmer_cache.kmer_to_index("A".as_bytes()), 1);
+        assert_eq!(kmer_cache.kmer_to_index("C".as_bytes()), 2);
+        assert_eq!(kmer_cache.kmer_to_index("AA".as_bytes()), 22);
+        assert_eq!(kmer_cache.kmer_to_index("DEMY".as_bytes()), 29798);
+        assert_eq!(kmer_cache.kmer_to_index("DEMYS".as_bytes()), 625774);
+
+        // assert_eq!(kmer_cache.index_to_kmer(1), "A".as_bytes());
+        // assert_eq!(kmer_cache.index_to_kmer(2), "C".as_bytes());
+        // assert_eq!(kmer_cache.index_to_kmer(22), "AA".as_bytes());
+        assert_eq!(kmer_cache.index_to_kmer(29798), "DEMY".as_bytes());
+        assert_eq!(kmer_cache.index_to_kmer(625774), "DEMYS".as_bytes());
+    }
+}
diff --git a/sa-index/src/lib.rs b/sa-index/src/lib.rs
index f276906..8c47f84 100644
--- a/sa-index/src/lib.rs
+++ b/sa-index/src/lib.rs
@@ -4,6 +4,7 @@ pub mod binary;
 pub mod peptide_search;
 pub mod sa_searcher;
 pub mod suffix_to_protein_index;
+mod bounds_table;
 
 /// Represents a suffix array.
 pub enum SuffixArray {
diff --git a/sa-index/src/sa_searcher.rs b/sa-index/src/sa_searcher.rs
index d09c704..5f54987 100644
--- a/sa-index/src/sa_searcher.rs
+++ b/sa-index/src/sa_searcher.rs
@@ -1,5 +1,4 @@
 use std::{cmp::min, ops::Deref};
-
 use sa_mappings::proteins::{Protein, Proteins};
 
 use crate::{
@@ -7,6 +6,7 @@ use crate::{
     suffix_to_protein_index::{DenseSuffixToProtein, SparseSuffixToProtein, SuffixToProteinIndex},
     Nullable, SuffixArray
 };
+use crate::bounds_table::BoundsCache;
 
 /// Enum indicating if we are searching for the minimum, or maximum bound in the suffix array
 #[derive(Clone, Copy, PartialEq)]
@@ -121,6 +121,7 @@ impl Deref for DenseSearcher {
 ///   the functional analysis provided by Unipept
 pub struct Searcher {
     pub sa: SuffixArray,
+    pub kmer_cache: BoundsCache<3>,
     pub proteins: Proteins,
     pub suffix_index_to_protein: Box<dyn SuffixToProteinIndex>
 }
@@ -143,7 +144,30 @@ impl Searcher {
     ///
     /// Returns a new Searcher object
     pub fn new(sa: SuffixArray, proteins: Proteins, suffix_index_to_protein: Box<dyn SuffixToProteinIndex>) -> Self {
-        Self { sa, proteins, suffix_index_to_protein }
+        // Create a KTable with all possible 3-mers
+        let mut kmer_cache = BoundsCache::new("ACDEFGHIKLMNPQRSTVWY".to_string());
+
+        // Create the Searcher object
+        let mut searcher = Self { sa, kmer_cache, proteins, suffix_index_to_protein };
+
+        // Update the bounds for all 3-mers in the KTable
+        for i in 0..21_usize.pow(3) {
+            let kmer = searcher.kmer_cache.index_to_kmer(i);
+
+            if kmer.is_empty() || searcher.kmer_cache.get_kmer(&kmer).is_some() {
+                continue;
+            }
+
+            // Calculate stricter starting bounds for the 3-mers
+            let bounds = searcher.search_bounds(&kmer);
+
+            if let BoundSearchResult::SearchResult((min_bound, max_bound)) = bounds {
+                let min_bound = if min_bound == 0 { 0 } else { min_bound - 1 };
+                searcher.kmer_cache.update_kmer(&kmer, (min_bound, max_bound));
+            }
+        }
+
+        searcher
     }
 
     /// Compares the `search_string` to the `suffix`
@@ -225,8 +249,7 @@ impl Searcher {
     /// The second argument indicates the index of the minimum or maximum bound for the match
     /// (depending on `bound`)
     fn binary_search_bound(&self, bound: BoundSearch, search_string: &[u8]) -> (bool, usize) {
-        let mut left: usize = 0;
-        let mut right: usize = self.sa.len();
+        let (mut left, mut right) = self.kmer_cache.get_kmer(search_string).unwrap_or((0, self.sa.len()));
         let mut lcp_left: usize = 0;
         let mut lcp_right: usize = 0;
         let mut found = false;