diff --git a/requirements.txt b/requirements.txt
index 005fcae..058ca3a 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -3,7 +3,8 @@ consolekit>=1.2.1
 dom-toml>=0.4.0
 domdf-python-tools>=2.9.1
 handy-archives>=0.1.0
-mkrecipe>=0.3.0
+mkrecipe>=0.9.0
+packaging>=20.9
 pyproject-parser>=0.3.0
 shippinglabel>=0.15.0
 shippinglabel-conda>=0.1.0
diff --git a/whey_conda/__init__.py b/whey_conda/__init__.py
index a437327..032061b 100644
--- a/whey_conda/__init__.py
+++ b/whey_conda/__init__.py
@@ -46,6 +46,7 @@
 from domdf_python_tools.paths import PathPlus
 from domdf_python_tools.typing import PathLike
 from domdf_python_tools.words import word_join
+from mkrecipe import filter_reqs_by_py_version, filter_reqs_with_markers
 from mkrecipe.config import MkrecipeParser
 from pyproject_parser.classes import _NormalisedName
 from shippinglabel.checksum import get_record_entry
@@ -327,7 +328,7 @@ def get_runtime_requirements(self) -> List[ComparableRequirement]:
 		Returns a list of the project's runtime requirements.
 		"""
 
-		extras: List[Union[ComparableRequirement, str]] = []
+		extras: List[Union[str, ComparableRequirement]] = []
 
 		if self.config["conda-extras"] == "all":
 			extras.extend(chain.from_iterable(self.config["optional-dependencies"].values()))
@@ -341,14 +342,20 @@ def get_runtime_requirements(self) -> List[ComparableRequirement]:
 
 		# TODO: handle extras from the dependencies. Lookup the requirements in the wheel metadata.
 		#  Perhaps wait until exposed in PyPI API
-		all_requirements = prepare_requirements(chain(self.config["dependencies"], extra_requirements))
+		all_requirements: List[ComparableRequirement] = list(
+				filter_reqs_with_markers(self.config, chain(self.config["dependencies"], extra_requirements))
+				)
+		all_requirements = filter_reqs_by_py_version(self.config, all_requirements)
 
 		self._echo_if_v(
 				f"Checking dependencies against the following channels: "
 				f"{word_join(self.config['conda-channels'], use_repr=True)}"
 				)
 
-		all_requirements = validate_requirements(all_requirements, self.config["conda-channels"])
+		all_requirements = validate_requirements(
+				prepare_requirements(all_requirements),
+				self.config["conda-channels"],
+				)
 
 		requirements_entries = [req for req in all_requirements if req and req != "numpy"]
 
diff --git a/whey_conda/config.py b/whey_conda/config.py
index c2d4e1b..03f22ca 100644
--- a/whey_conda/config.py
+++ b/whey_conda/config.py
@@ -5,7 +5,7 @@
 Configuration for ``whey-conda``.
 """
 #
-#  Copyright © 2021 Dominic Davis-Foster <dominic@davis-foster.co.uk>
+#  Copyright © 2021-2024 Dominic Davis-Foster <dominic@davis-foster.co.uk>
 #
 #  Permission is hereby granted, free of charge, to any person obtaining a copy
 #  of this software and associated documentation files (the "Software"), to deal
@@ -31,6 +31,7 @@
 
 # 3rd party
 from dom_toml.parser import TOML_TYPES, AbstractConfigParser, BadConfigError, construct_path
+from packaging.version import Version
 from typing_extensions import Literal
 
 __all__ = ("WheyCondaParser", )
@@ -40,10 +41,16 @@ class WheyCondaParser(AbstractConfigParser):
 	"""
 	Parser for the ``[tool.whey-conda]`` table from ``pyproject.toml``.
 
-	.. autosummary-widths:: 7/16
+	.. autosummary-widths:: 6/16
 	"""
 
-	defaults = {"conda-description": "%s", "conda-extras": "none", "conda-channels": ("conda-forge", )}
+	defaults = {
+			"conda-description": "%s",
+			"conda-extras": "none",
+			"conda-channels": ("conda-forge", ),
+			"min-python-version": None,
+			"max-python-version": None
+			}
 
 	table_name = ("tool", "whey-conda")
 
@@ -124,7 +131,7 @@ def parse_conda_extras(
 
 		extras = config["conda-extras"]
 
-		path_elements = [*self.table_name, "conda-extras"]  # pylint: disable=use-tuple-over-list
+		path_elements = (*self.table_name, "conda-extras")
 
 		if isinstance(extras, str):
 			extras_lower = extras.lower()
@@ -143,6 +150,36 @@ def parse_conda_extras(
 
 		return extras
 
+	def parse_min_python_version(self, config: Dict[str, TOML_TYPES]) -> int:
+		"""
+		Parse the ``min-python-version`` key, giving the minimum Python 3.x version to consider requirements for.
+
+		:param config: The unparsed TOML config for the ``[tool.whey-conda]`` table.
+
+		:rtype:
+
+		.. versionadded:: 0.3.0
+		"""
+
+		v = Version(str(config["min-python-version"]))
+		assert v.major == 3
+		return v.minor
+
+	def parse_max_python_version(self, config: Dict[str, TOML_TYPES]) -> int:
+		"""
+		Parse the ``max-python-version`` key, giving the maximum Python 3.x version to consider requirements for.
+
+		:param config: The unparsed TOML config for the ``[tool.whey-conda]`` table.
+
+		:rtype:
+
+		.. versionadded:: 0.3.0
+		"""
+
+		v = Version(str(config["max-python-version"]))
+		assert v.major == 3
+		return v.minor
+
 	@property
 	def keys(self) -> List[str]:
 		"""
@@ -153,6 +190,8 @@ def keys(self) -> List[str]:
 				"conda-description",
 				"conda-channels",
 				"conda-extras",
+				"min-python-version",
+				"max-python-version",
 				]
 
 	def parse(