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Kabat numbering of light chains puts insertions on 52 position. #73

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dudzicp opened this issue Dec 7, 2023 · 0 comments
Open

Kabat numbering of light chains puts insertions on 52 position. #73

dudzicp opened this issue Dec 7, 2023 · 0 comments

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@dudzicp
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dudzicp commented Dec 7, 2023

According to the definition (https://books.google.pl/books?id=OpW8-ibqyvcC&printsec=frontcover&source=gbs_ge_summary_r&cad=0#v=onepage&q&f=false) light chains should not have insertions allowed on the position 52 (for heavy chain it is allowed).

When I number aa sequence of light chain, RPVLTQPPSLSASPGATARLPCTLSSDLSVGGKNMFWYQQKPGSSPRLFLYHYSDSDKQLGPGVPSRVSGSKETSSNTAFLLISGLQPEDEADYYCQVYESSAN
the results show insertions on 52 position, which should not be allowed according to schema definition.

How could this be explained?
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