diff --git a/cairo_programs/blake2s_felts.cairo b/cairo_programs/blake2s_felts.cairo
index fd913b2a..6212bb93 100644
--- a/cairo_programs/blake2s_felts.cairo
+++ b/cairo_programs/blake2s_felts.cairo
@@ -1,6 +1,6 @@
 %builtins range_check bitwise
 
-from starkware.cairo.common.bool import TRUE
+from starkware.cairo.common.bool import TRUE, FALSE
 from starkware.cairo.common.alloc import alloc
 from starkware.cairo.common.cairo_blake2s.blake2s import blake2s_felts
 from starkware.cairo.common.cairo_builtins import BitwiseBuiltin
@@ -26,10 +26,20 @@ func main{range_check_ptr, bitwise_ptr: BitwiseBuiltin*}() {
     assert inputs[15] = 74256930;
     let (local blake2s_ptr_start) = alloc();
     let blake2s_ptr = blake2s_ptr_start;
+
+    // Bigendian
     let (result) = blake2s_felts{range_check_ptr=range_check_ptr, blake2s_ptr=blake2s_ptr}(
         16, inputs, TRUE
     );
     assert result.low = 23022179997536219430502258022509199703;
     assert result.high = 136831746058902715979837770794974289597;
+
+    // Little endian
+    let (result) = blake2s_felts{range_check_ptr=range_check_ptr, blake2s_ptr=blake2s_ptr}(
+        16, inputs, FALSE
+    );
+    assert result.low = 315510691254085211243916597439546947220;
+    assert result.high = 42237338665522721102428636006748876126;
+
     return ();
 }
diff --git a/cairo_programs/blake2s_integration_tests.cairo b/cairo_programs/blake2s_integration_tests.cairo
new file mode 100644
index 00000000..a4636757
--- /dev/null
+++ b/cairo_programs/blake2s_integration_tests.cairo
@@ -0,0 +1,75 @@
+%builtins range_check bitwise
+
+from starkware.cairo.common.alloc import alloc
+from starkware.cairo.common.cairo_blake2s.blake2s import blake2s, finalize_blake2s, blake2s_felts
+from starkware.cairo.common.cairo_builtins import BitwiseBuiltin
+from starkware.cairo.common.uint256 import Uint256
+from starkware.cairo.common.bool import TRUE
+
+func fill_array(array: felt*, base: felt, step: felt, array_length: felt, iterator: felt) {
+    if (iterator == array_length) {
+        return ();
+    }
+    assert array[iterator] = base + step * iterator;
+    return fill_array(array, base, step, array_length, iterator + 1);
+}
+
+func test_integration{range_check_ptr, bitwise_ptr: BitwiseBuiltin*}(iter: felt, last: felt) {
+    alloc_locals;
+    if (iter == last) {
+        return ();
+    }
+
+    let (data: felt*) = alloc();
+    fill_array(data, iter, 2 * iter, 10, 0);
+
+    let (local blake2s_ptr_start) = alloc();
+    let blake2s_ptr = blake2s_ptr_start;
+    let (res_1: Uint256) = blake2s{range_check_ptr=range_check_ptr, blake2s_ptr=blake2s_ptr}(
+        data, 9
+    );
+
+    finalize_blake2s(blake2s_ptr_start, blake2s_ptr);
+
+    let (local blake2s_ptr_start) = alloc();
+    let blake2s_ptr = blake2s_ptr_start;
+
+    let (data_2: felt*) = alloc();
+    assert data_2[0] = res_1.low;
+    assert data_2[1] = res_1.high;
+
+    let (res_2) = blake2s_felts{range_check_ptr=range_check_ptr, blake2s_ptr=blake2s_ptr}(
+        2, data_2, TRUE
+    );
+
+    finalize_blake2s(blake2s_ptr_start, blake2s_ptr);
+
+    if (iter == last - 1 and last == 10) {
+        assert res_1.low = 327684140823325841083166505949840946643;
+        assert res_1.high = 28077572547397067729112288485703133566;
+        assert res_2.low = 323710308182296053867309835081443411626;
+        assert res_2.high = 159988406782415793602959692147600111481;
+    }
+
+    if (iter == last - 1 and last == 100) {
+        assert res_1.low = 26473789897582596397897414631405692327;
+        assert res_1.high = 35314462001555260569814614879256292984;
+        assert res_2.low = 256911263205530722270005922452382996929;
+        assert res_2.high = 248798531786594770765531047659644061441;
+    }
+
+    return test_integration(iter + 1, last);
+}
+
+func run_tests{range_check_ptr, bitwise_ptr: BitwiseBuiltin*}(last: felt) {
+    alloc_locals;
+    test_integration(0, last);
+
+    return ();
+}
+
+func main{range_check_ptr, bitwise_ptr: BitwiseBuiltin*}() {
+    run_tests(10);
+
+    return ();
+}
diff --git a/pkg/vm/cairo_run/cairo_run_test.go b/pkg/vm/cairo_run/cairo_run_test.go
index 7927f305..dd870078 100644
--- a/pkg/vm/cairo_run/cairo_run_test.go
+++ b/pkg/vm/cairo_run/cairo_run_test.go
@@ -360,3 +360,7 @@ func TestBlake2sFelts(t *testing.T) {
 func TestFinalizeBlake2s(t *testing.T) {
 	testProgram("finalize_blake2s", t)
 }
+
+func TestBlake2sIntegrationTests(t *testing.T) {
+	testProgram("blake2s_integration_tests", t)
+}