diff --git a/tools/amplican/macros.xml b/tools/amplican/macros.xml
index 1c5c1beedef..79aa418567a 100644
--- a/tools/amplican/macros.xml
+++ b/tools/amplican/macros.xml
@@ -1,5 +1,5 @@
 <macros>
-    <token name="@TOOL_VERSION@">1.20.0</token>
+    <token name="@TOOL_VERSION@">1.22.1</token>
     <token name="@SUFFIX_VERSION@">0</token>
     <xml name="bio_tools">
         <xrefs>