diff --git a/lib/galaxy/webapps/galaxy/api/users.py b/lib/galaxy/webapps/galaxy/api/users.py
index 51b5dcea8ebd..cea38b00bdf8 100644
--- a/lib/galaxy/webapps/galaxy/api/users.py
+++ b/lib/galaxy/webapps/galaxy/api/users.py
@@ -832,7 +832,11 @@ def get_information(self, trans, id, **kwd):
                     "type": "text",
                     "label": "Email address",
                     "value": email,
-                    "help": "If you change your email address you will receive an activation link in the new mailbox and you have to activate your account by visiting it.",
+                    "help": (
+                        "If you change your email address you will receive an activation link in the new mailbox and you have to activate your account by visiting it."
+                        if trans.app.config.user_activation_on
+                        else ""
+                    ),
                 }
             )
         if is_galaxy_app: