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Question regarding min_cnv_length parameter #39

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reshu23 opened this issue Oct 24, 2024 · 0 comments
Open

Question regarding min_cnv_length parameter #39

reshu23 opened this issue Oct 24, 2024 · 0 comments

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@reshu23
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reshu23 commented Oct 24, 2024

Dear Team,
I am using latest version of Spectre. I know, Spectre has been optimized for CNV call >=100KB. I would like to use min_cnv_len=85KB or 90KB, so I can capture events between 85/90KB to 100KB. Reducing min cnv length can give rise to false positives. I am using breakpoint support also(--snfj). Would you like to suggest modification in any other parameters along with min_cnv_len=85/90KB, which can reduce false positives? OR I should not try it at all. Your suggestions will be helpful.
Thank you.

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