A simple buildout to run Euphorie Installation You need to add a custom.cfg file to the buildout root directory. This file should contains something like: [settings] main-package = your.euphorie.flavour Create a buildout.cfg, you can symlink one in the profiles folder, e.g.: ln -s profiles/development.cfg buildout.cfg Run make Setup alembic table on a fresh DB: # Creates the table if missing ./bin/alembic --config etc/alembic.ini ensure_version # Sets the last version ./bin/alembic --config etc/alembic.ini stamp `./bin/alembic --config etc/alembic.ini heads|awk '{print $1}'`