diff --git a/ChangeLog b/ChangeLog index 50a27f8..a44b0ab 100644 --- a/ChangeLog +++ b/ChangeLog @@ -1,3 +1,11 @@ +Changes from Version 1.13 to 2.0.0 [July 30 2016] + +* Major modification of the algorithm to explore haplotype variability (more than one order of magnitude faster), including parallelization +* Major modification of the data2haplohh function to improve reading efficiency and allele recoding. In addition, a new input data file format (haplotype.in.columns) is now available +* Computation of xp-EHH +* A vignette that details how to use the package is now included in the package +* Several other minor modifications in other functions + Changes from Version 1.12 to 1.13 [May 13 2015] * Removing smartlegend() calls (deprecated in new version of gplot) in calc_ehh.R and fistribplot.R diff --git a/DESCRIPTION b/DESCRIPTION index 797a3a4..4ec22d5 100644 --- a/DESCRIPTION +++ b/DESCRIPTION @@ -1,18 +1,20 @@ Package: rehh Maintainer: Mathieu Gautier -Author: Mathieu Gautier and Renaud Vitalis -Version: 1.13 +Author: Mathieu Gautier, Alexander Klassmann and Renaud Vitalis +Version: 2.0.0 License: GPL (>= 2) Title: Searching for Footprints of Selection using Haplotype Homozygosity Based Tests Description: Functions for the detection of footprints of selection on dense SNP data using Extended Homozygosity Haplotype (EHH) based tests. The package includes computation of EHH, iHS - (within population) and Rsb (across pairs of populations) + (within population) and Rsb or XP-EHH (across pairs of populations) statistics. Various plotting functions are also included to facilitate visualization and interpretation of the results. Depends: R (>= 2.10), gplots, methods +Suggests: knitr, rmarkdown +VignetteBuilder: knitr NeedsCompilation: yes -Packaged: 2015-05-13 14:36:55 UTC; mathieu +Packaged: 2016-08-01 12:46:28 UTC; mathieu Repository: CRAN -Date/Publication: 2015-05-13 19:54:58 +Date/Publication: 2016-08-01 15:35:27 diff --git a/MD5 b/MD5 index ac1223c..b82e26e 100644 --- a/MD5 +++ b/MD5 @@ -1,42 +1,56 @@ -6984428c4aa45239a5a0b97e84240d5b *ChangeLog -eb7e311e133b8ff8b8f1dee961730365 *DESCRIPTION -bcdae995c3c93898c7f6adc04767cc5c *NAMESPACE +0d7cb76701f9400146447856aa473fd8 *ChangeLog +71620313c7e3a4866190332e8d1d5883 *DESCRIPTION +05b360a82b2bd675ab11bd88a90b393c *NAMESPACE 66b19d927cd1910977ea9a424e808f09 *R/bifurcation.diagram.R -67d44ad2dea81d0183e1cab53a577563 *R/calc_ehh.R -f2ff441060f34c66e0ae54153d83468f *R/calc_ehhs.R -ae6d29a3c3fd66aba573924440851407 *R/data2haplohh.R -b4bc9634a424e3aa52346765577a964d *R/distribplot.R -85a4171cae44228896492839af39bb68 *R/ies2rsb.R -b76e82e3b88c8c45377c0cc854bff0d2 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+b223f181cf1e51b26fcce58242e451d2 *src/hh_utils.h +80ac2e78110aa3e54fb5ce824bd5574f *vignettes/genetics.csl +904b52d7f42d303d82f763336fe02422 *vignettes/rehh.Rmd +1e78f3b2a2af30127833e772ce889507 *vignettes/rehh.html +5eb01f115834ab23893ed2278d9e1b20 *vignettes/vignette.bib diff --git a/NAMESPACE b/NAMESPACE index 6c9f229..e9c755e 100644 --- a/NAMESPACE +++ b/NAMESPACE @@ -7,11 +7,18 @@ export(calc_ehhs) export(data2haplohh) export(distribplot) export(ies2rsb) +export(ies2xpehh) export(ihh2ihs) export(ihsplot) export(make.example.files) export(rsbplot) export(scan_hh) +export(xpehhplot) import(gplots) import(methods) +importFrom("grDevices", "dev.new") +importFrom("graphics", "abline", "axis", "curve", "legend", "lines","matplot", "par", "plot", "plot.new") +importFrom("stats", "density", "dnorm", "median", "pnorm", "qqnorm","sd") +importFrom("utils", "read.table", "tail") + diff --git a/R/calc_ehh.R b/R/calc_ehh.R index 6891d90..6b0ddf7 100644 --- a/R/calc_ehh.R +++ b/R/calc_ehh.R @@ -1,39 +1,59 @@ -calc_ehh<-function(haplohh,mrk,limhaplo=2,limehh=0.05,plotehh=TRUE,main_leg="EHH plot"){ - if(!(is.haplohh(haplohh))){stop("Data oject is not of valid haplohh object... (see data2haplohh() function)")} - if(mrk<1 | mrk>haplohh@nsnp){stop(paste("Focal snp index must be between",1,"and",haplohh@nsnp))} - if(limhaplo<2){stop("limhaplo must be >1")} - if(limehh<0 | limehh>1){stop("limehh must be between 0 and 1")} - - ehh<-matrix(0,nrow=haplohh@nsnp,ncol=2) ; nhaplo_eval<-matrix(0,nrow=haplohh@nsnp,ncol=2) ; ihh<-rep(0,2) - res.ehh<-.C("r_ehh", - Rdata = as.integer(haplohh@haplo), - number_SNPs = as.integer(haplohh@nsnp), - number_chromosomes = as.integer(haplohh@nhap), - focal_SNP = as.integer(mrk), - map = as.double(haplohh@position), - number_haplotypes = as.integer(nhaplo_eval), - EHH = as.double(ehh), - IHH = as.double(ihh), - min_number_haplotypes = as.integer(limhaplo), - min_EHH = as.double(limehh) - ) - - ehh=matrix(res.ehh$EHH,2,haplohh@nsnp,byrow=T) - nhaplo_eval=matrix(res.ehh$number_haplotypes,2,haplohh@nsnp,byrow=T) - rownames(ehh)=rownames(nhaplo_eval)=c("Anc. Allele","Der. Allele") - colnames(ehh)=colnames(nhaplo_eval)=haplohh@snp.name - ihh=res.ehh$IHH ; names(ihh)=c("Anc. Allele","Der. Allele") - - if(plotehh){ - sel_reg<-(colSums(nhaplo_eval)>0) - if(sum(sel_reg)>0){ - matplot(haplohh@position[sel_reg],t(ehh[,sel_reg]),col=c("red","blue"),lty=1, - type="l",main=main_leg,bty="n",xlab="Position",ylab="EHH") - abline(v=haplohh@position[mrk],lty=2) - legend("left","top",c("Anc. Allele","Der. Allele"),col=c("red","blue"),bty="n",lty=1) - } - } - - return(list(ehh=ehh,nhaplo_eval=nhaplo_eval,freq_all1=nhaplo_eval[1,mrk]/sum(nhaplo_eval[,mrk]),ihh=ihh)) - +calc_ehh <- function(haplohh,mrk,limhaplo = 2,limehh = 0.05,plotehh = TRUE,lty = 1,lwd = 1.5,col = c("blue","red"),xlab = "Position",ylab = expression(Extended~haplotype~homozygosity~(italic(EHH))),cex.lab = 1.25,main = NA,cex.main = 1.5) { + if (!(is.haplohh(haplohh))) {stop("The data are not formatted as a valid haplohh object... (see the data2haplohh() function)")} + if (mrk < 1 | mrk > haplohh@nsnp) {stop(paste("The focal SNP index must lie between",1,"and",haplohh@nsnp))} + if (limhaplo < 2) {stop("limhaplo must be larger than 1")} + if (limehh < 0 | limehh > 1) {stop("limehh must lie between 0 and 1")} + ehh <- nhaplo_eval <- matrix(0,nrow = haplohh@nsnp,ncol = 2) + ihh <- rep(0,2) + res.ehh <- .C("CALL_EHH", + Rdata = as.integer(haplohh@haplo), + focal_SNP = as.integer(mrk), + number_SNPs = as.integer(haplohh@nsnp), + number_chromosomes = as.integer(haplohh@nhap), + number_haplotypes = as.integer(nhaplo_eval), + min_number_haplotypes = as.integer(limhaplo), + min_EHH = as.double(limehh), + map = as.double(haplohh@position), + EHH = as.double(ehh), + IHH = as.double(ihh) + ) + nhaplo_eval = matrix(res.ehh$number_haplotypes,2,haplohh@nsnp,byrow = T) + ehh = matrix(res.ehh$EHH,2,haplohh@nsnp,byrow = T) + rownames(ehh) = rownames(nhaplo_eval) = c("Ancestral allele","Derived allele") + colnames(ehh) = colnames(nhaplo_eval) = haplohh@snp.name + ihh = res.ehh$IHH + names(ihh) = c("Ancestral allele","Derived allele") + if (plotehh) { + sel_reg <- (colSums(nhaplo_eval) > 0) + if (sum(sel_reg) > 0) { + if (max(haplohh@position[sel_reg]) < 1e3) { + scale <- 1 + unit = "(bp)" + } + else if (max(haplohh@position[sel_reg]) < 1e6) { + scale <- 1e3 + unit = "(kb)" + } + else if (max(haplohh@position[sel_reg]) < 1e9) { + scale <- 1e6 + unit = "(Mb)" + } + else { + scale <- 1e9 + unit = "(Gb)" + } + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + matplot(haplohh@position[sel_reg] / scale,t(ehh[,sel_reg]),col = col,type = "l",lty = lty,lwd = lwd,main = main,bty = "n",xlab = paste(xlab,unit),ylab = ylab,cex.lab = cex.lab, cex.main = cex.main) + abline(v = haplohh@position[mrk] / scale,lty = 2) + if (haplohh@position[mrk] > sum(range(haplohh@position[sel_reg])) / 2) { + legend("topleft",c("Ancestral allele","Derived allele"),col = col,bty = "n",lty = lty,lwd = lwd) + } + else { + legend("topright",c("Ancestral allele","Derived allele"),col = col,bty = "n",lty = lty,lwd = lwd) + } + } + } + return(list(ehh = ehh,nhaplo_eval = nhaplo_eval,freq_all1 = nhaplo_eval[1,mrk] / sum(nhaplo_eval[,mrk]),ihh = ihh)) } diff --git a/R/calc_ehhs.R b/R/calc_ehhs.R index 13440c5..2f02018 100644 --- a/R/calc_ehhs.R +++ b/R/calc_ehhs.R @@ -1,36 +1,69 @@ -calc_ehhs<-function(haplohh,mrk,limhaplo=2,limehhs=0.05,plotehhs=TRUE,main_leg="EHHS plot"){ - if(!(is.haplohh(haplohh))){stop("Data oject is not of valid haplohh object... (see data2haplohh() function)")} - if(mrk<1 | mrk>haplohh@nsnp){stop(paste("Focal snp index must be between",1,"and",haplohh@nsnp))} - if(limhaplo<2){stop("limhaplo must be >1")} - if(limehhs<0 | limehhs>1){stop("limehhs must be between 0 and 1")} - - nhaplo_eval<-rep(0,haplohh@nsnp) ; ehhs<-rep(0,haplohh@nsnp) ; ies<-0 - res.ehhs<-.C("r_ehhs", - Rdata = as.integer(haplohh@haplo), - number_SNPs = as.integer(haplohh@nsnp), - number_chromosomes = as.integer(haplohh@nhap), - focal_SNP = as.integer(mrk), - map = as.double(haplohh@position), - number_haplotypes = as.integer(nhaplo_eval), - EHHS = as.double(ehhs), - IES = as.double(ies), - min_number_haplotypes = as.integer(limhaplo), - min_EHH = as.double(limehhs) - ) +calc_ehhs <- function(haplohh,mrk,limhaplo = 2,limehhs = 0.05,plotehhs = TRUE,lty = 1,lwd = 1.5,col = c("blue","red"),xlab = "Position",ylab = expression(Site~specific~italic(EHH)~(italic(EHHS))),cex.lab = 1.25,main = NA,cex.main = 1.5) { - ehhs=res.ehhs$EHHS ; nhaplo_eval=res.ehhs$number_haplotypes - names(ehhs)=names(nhaplo_eval)=haplohh@snp.name - + if (!(is.haplohh(haplohh))) {stop("The data are not formatted as a valid haplohh object... (see the data2haplohh() function)")} + if (mrk < 1 | mrk > haplohh@nsnp) {stop(paste("The focal SNP index must lie between",1,"and",haplohh@nsnp))} + if (limhaplo < 2) {stop("limhaplo must be larger than 1")} + if (limehhs < 0 | limehhs > 1) {stop("limehhs must lie between 0 and 1")} - if(plotehhs){ - sel_reg<-(nhaplo_eval>0) - if(sum(sel_reg)>0){ - plot(haplohh@position[sel_reg],ehhs[sel_reg],col=c("red"),lty=1, - type="l",main=main_leg,bty="n",xlab="Position",ylab="EHHS") - abline(v=haplohh@position[mrk],lty=2) - } - } - - return(list(ehhs=ehhs,nhaplo_eval=nhaplo_eval,ies=res.ehhs$IES)) + nhaplo_eval <- ehhs_tang <- ehhs_sabeti <- rep(0,haplohh@nsnp) + ies_tang <- ies_sabeti <- 0 + res.ehhs <- .C("CALL_EHHS", + Rdata = as.integer(haplohh@haplo), + focal_SNP = as.integer(mrk), + number_SNPs = as.integer(haplohh@nsnp), + number_chromosomes = as.integer(haplohh@nhap), + number_haplotypes = as.integer(nhaplo_eval), + min_number_haplotypes = as.integer(limhaplo), + min_EHHS = as.double(limehhs), + map = as.double(haplohh@position), + EHHS_TANG = as.double(ehhs_tang), + IES_TANG = as.double(ies_tang), + EHHS_SABETI = as.double(ehhs_sabeti), + IES_SABETI = as.double(ies_sabeti) + ) + + nhaplo_eval = res.ehhs$number_haplotypes + ehhs_tang = res.ehhs$EHHS_TANG + ies_tang = res.ehhs$IES_TANG + ehhs_sabeti = res.ehhs$EHHS_SABETI + ies_sabeti = res.ehhs$IES_SABETI + names(ehhs_tang) = names(ehhs_sabeti) = names(nhaplo_eval) = haplohh@snp.name + + if (plotehhs) { + sel_reg <- (nhaplo_eval > 0) + if (sum(sel_reg) > 0) { + if (max(haplohh@position[sel_reg]) < 1e3) { + scale <- 1 + unit = "(bp)" + } + else if (max(haplohh@position[sel_reg]) < 1e6) { + scale <- 1e3 + unit = "(kb)" + } + else if (max(haplohh@position[sel_reg]) < 1e9) { + scale <- 1e6 + unit = "(Mb)" + } + else { + scale <- 1e9 + unit = "(Gb)" + } + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(haplohh@position[sel_reg] / scale,ehhs_sabeti[sel_reg],col = col[1],type = "l",lty = lty,lwd = lwd,main = main,bty = "n",xlab = paste(xlab,unit),ylab = ylab,cex.lab = cex.lab, cex.main = cex.main) + lines(haplohh@position[sel_reg] / scale,ehhs_tang[sel_reg],col = col[2],lty = lty,lwd = lwd) + abline(v = haplohh@position[mrk] / scale,lty = 2) + if (haplohh@position[mrk] > sum(range(haplohh@position[sel_reg])) / 2) { + legend("topleft",c("Sabeti et al. (2007)","Tang et al. (2007)"),col = col,bty = "n",lty = lty,lwd = lwd) + + } + else { + legend("topright",c("Sabeti et al. (2007)","Tang et al. (2007)"),col = col,bty = "n",lty = lty,lwd = lwd) + } + } + } + + return(list(nhaplo_eval = nhaplo_eval,EHHS_Tang_et_al_2007 = ehhs_tang,IES_Tang_et_al_2007 = ies_tang,EHHS_Sabeti_et_al_2007 = ehhs_sabeti,IES_Sabeti_et_al_2007 = ies_sabeti)) } diff --git a/R/data2haplohh.R b/R/data2haplohh.R index fd5aa12..1dc4db7 100644 --- a/R/data2haplohh.R +++ b/R/data2haplohh.R @@ -1,5 +1,5 @@ setClass(Class = "haplohh", - representation(haplo = "matrix",position = "numeric",snp.name="character",chr.name = "numeric",nhap = "numeric",nsnp = "numeric") + representation(haplo = "matrix",position = "numeric",snp.name="character",chr.name = "character",nhap = "numeric",nsnp = "numeric") ) @@ -14,23 +14,25 @@ make.example.files <- function() { file.copy(system.file('bta12_hapguess_switch.out',package='rehh'),'bta12_hapguess_switch.out') file.copy(system.file('map.inp',package='rehh'),'map.inp') file.copy(system.file('bta12_cgu.hap',package='rehh'),'bta12_cgu.hap') + file.copy(system.file('bta12_cgu.thap',package='rehh'),'bta12_cgu.thap') } -data2haplohh<-function(hap_file,map_file,min_maf=0,min_perc_geno.hap=100,min_perc_geno.snp=100,chr.name=NA,popsel=NA,recode.allele=FALSE){ +data2haplohh<-function(hap_file,map_file,min_maf=0,min_perc_geno.hap=100,min_perc_geno.snp=100,chr.name=NA,popsel=NA,recode.allele=FALSE,haplotype.in.columns=FALSE){ res<-new("haplohh") - +if(min_perc_geno.hap<0 | min_perc_geno.hap>100){stop("The value for the argument min_perc_geno.hap should lie between 0 and 100")} +if(min_perc_geno.snp<0 | min_perc_geno.snp>100){stop("The value for the argument min_perc_geno.snp should lie between 0 and 100")} #####Fichier map (verification) -map<-read.table(map_file,row.names=1) #snp name, chromosome, position, allele ancestral, allele derive +map<-read.table(map_file,row.names=1,colClasses="character") #snp name, chromosome, position, allele ancestral, allele derive if(ncol(map)!=4){ cat("Wrong format for map data file: ",map_file,"\n Should contain 5 columns (Snp name, Chromosome Number, Position, Ancestral Allele and Derived Allele) and no header\n") stop("Conversion stopped") }else{ - tmp_chr=unique(as.numeric(map[,1])) + tmp_chr=unique(as.character(map[,1])) if(length(tmp_chr)!=1 & is.na(chr.name)){ cat("More than one chromosome name in Map file:",map_file,"\n") repeat { - cat('Which chromosome should be considered among:',tmp_chr,"\n") - chr.name <- scan(file = '',n = 1,what = integer(0),quiet = TRUE) + cat('Which chromosome should be considered among:\n',tmp_chr,"\n") + chr.name <- scan(file = '',n = 1,what = character(),quiet = TRUE) if (chr.name %in% tmp_chr) break } } @@ -41,16 +43,16 @@ map<-read.table(map_file,row.names=1) #snp name, chromosome, position, allele an if(nrow(map)==0){ cat("No SNPs mapping to chromosome ",chr.name," are found in the map file\n") tmp_chr=unique(as.character(map[,1])) - cat("Here is the list of chromosome names in the map file:",tmp_chr,"\n") + cat("Here is the list of chromosome names in the map file:\n",tmp_chr,"\n") stop("Conversion stopped") } #premier checks OK - res@chr.name<-chr.name + res@chr.name<-as.character(chr.name) res@snp.name<-tmp_nom tmp_pos<-as.numeric(map[,2]) if(sum(diff(tmp_pos)<0)>0){ - stop("SNP should be ordered on the map, check also that both haplotypes (column of haplo) and map (row of map) are ordered in the same way")} + stop("SNP should be ordered on the map, check also that both haplotypes (column of haplo)\nand map (row of map) are ordered in the same way")} if(sum(diff(tmp_pos)==0)>0){ warning("Some SNPs map to the same position")} res@position<-tmp_pos @@ -60,10 +62,22 @@ res@nsnp=nrow(map) cat("Map file seems OK:",res@nsnp," SNPs declared for chromosome",res@chr.name,"\n") ###Fichier haplo - -out_fphase<-scan(hap_file,what="character",sep="\n",quiet=TRUE,nlines=15) -test_fphase_1=grep("fastPHASE",out_fphase) -test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) +if(haplotype.in.columns){ + cat("Haplotype are in columns with no header\n") + tmp.nhap=length(unlist(strsplit(readLines(hap_file,n=1),split="\t|\\s+"))) + tmp_haplos=matrix(scan(hap_file,what="character",quiet=TRUE),nrow=tmp.nhap) +# tmp_haplos=t(as.matrix(read.table(hap_file,colClasses="numeric"))) +# tmp_haplos=readChar(hap_file,file.info(hap_file)$size,useBytes=T) +# tmp_haplos=matrix(strsplit(gsub(tmp_haplos,pattern="\n|\t|\\s+",replacement=" "),split=" ",useBytes=T,fixed=T)[[1]],nrow=182) + tmp.nsnp=ncol(tmp_haplos) + if(tmp.nsnp!=res@nsnp){ + cat("The number of snp in the haplotypes",tmp.nsnp," is not equal\nto the number of snps declared in the map file",res@nsnp,"\n") + stop("Conversion stopped") + } +}else{ + out_fphase<-scan(hap_file,what="character",sep="\n",quiet=TRUE,nlines=15) + test_fphase_1=grep("fastPHASE",out_fphase) + test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) if(length(test_fphase_1)>0 & length(test_fphase_2)>0){ #fichier fastphase cat("Looks like a FastPHASE haplotype file\n") @@ -85,7 +99,7 @@ test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) cat("Haplotypes originate from ",length(liste_pop)," different populations in the fastPhase output file\n") if(!(popsel %in% pop_label)){ - cat("Chosen pop. is not in the list of pop. number:",liste_pop,"\n") + cat("Chosen pop. is not in the list of pop. number:\n",liste_pop,"\n") popsel=NA } if(is.na(popsel)){ #on demande interactivement la pop a selectionner @@ -103,7 +117,7 @@ test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) if(!(is.na(popsel))){ #bizarre car pas de sous population observe cat('No popsel are thus considered:',liste_pop,"\n") } -} + } nlignes=length(out_fphase) ; nind=nlignes/3 ; nhap=2*nind tmp_haplos=matrix(,nhap,res@nsnp) @@ -122,42 +136,41 @@ test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) }else{tmp_haplos[hap2_index,]=hap2} } -}else{ #fichier au format standard + }else{ #fichier au format standard cat("Standard rehh input file assumed\n") - tmp_haplos=as.matrix(read.table(hap_file,row.names=1)) - if(ncol(tmp_haplos)!=res@nsnp){ - cat("The number of snp in the haplotypes",ncol(tmp_haplos)," is not equal to the number of snps declared in the map file",res@nsnp,"\n") + tmp.ncol=length(unlist(strsplit(readLines(hap_file,n=1),split="\t|\\s+"))) #retrocompatibilite: ca marchait avec la tabulation avant + tmp.nsnp=tmp.ncol-1 #retrocompatibilite: les haplos contiennent un ID + if(tmp.nsnp!=res@nsnp){ + cat("The number of snp in the haplotypes",tmp.nsnp," is not equal\nto the number of snps declared in the map file",res@nsnp,"\n") stop("Conversion stopped") - } -} - + } + tmp_haplos=matrix(scan(hap_file,what="character",quiet=TRUE),ncol=tmp.ncol,byrow=TRUE)[,-1] + } + } res@nhap=nrow(tmp_haplos) - ##recodage des alleles si necessaire - if(recode.allele){ - cat("Please Wait: alleles are recoded according to map file as: 0 (missing data), 1 (ancestral allele) or 2 (derived allele)\n") - res@haplo=matrix(0,res@nhap,res@nsnp) - anc_allele=as.character(map[,3]) ; der_allele=as.character(map[,4]) - for(i in 1:res@nsnp){ - all_anc= (as.character(tmp_haplos[,i])==anc_allele[i]) - all_der= (as.character(tmp_haplos[,i])==der_allele[i]) - all_miss= ((all_anc + all_der)==0) - res@haplo[all_anc,i]=1 ; res@haplo[all_der,i]=2 ; res@haplo[all_miss,i]=0 - tmp_nmiss=sum(all_miss) - if(tmp_nmiss>0){cat(tmp_nmiss," missing allele for SNP: ",res@snp.name[i],"\n")} - if(i%%10==0){cat("SNP #",i," out of",res@nsnp,"\n")} - } + if(recode.allele){ + cat("Alleles are being recoded according to map file as:\n\t0 (missing data), 1 (ancestral allele) or 2 (derived allele)\n") + anc_allele=matrix(rep(map[,3],res@nhap),res@nhap,res@nsnp,byrow=TRUE) + all_anc=tmp_haplos==anc_allele + rm(anc_allele) + der_allele=matrix(rep(map[,4],res@nhap),res@nhap,res@nsnp,byrow=TRUE) + all_der=tmp_haplos==der_allele + rm(der_allele) + rm(tmp_haplos) + res@haplo=matrix(0,res@nhap,res@nsnp) + res@haplo[all_anc]=1 ; res@haplo[all_der]=2 }else{ - if(sum(!(tmp_haplos==0 | tmp_haplos==1 | tmp_haplos==2 ))>0){ - cat("Alleles are not coded in the appropriate format: 0 (missing data), 1 (ancestral allele) or 2 (derived allele)\n") - cat("Check your data or use recode.allele=TRUE option to recode according to the map information\n") - stop("Conversion stopped") - } - res@haplo=matrix(as.numeric(tmp_haplos),res@nhap,res@nsnp) - } - + if(sum(!(tmp_haplos=="0" | tmp_haplos=="1" | tmp_haplos=="2" ))>0){ + cat("Alleles are not coded in the appropriate format:\n\t0 (missing data), 1 (ancestral allele) or 2 (derived allele)\n") + cat("Check your data or use recode.allele=TRUE option to recode according to the map information\n") + stop("Conversion stopped") + } + res@haplo=matrix(as.numeric(tmp_haplos),res@nhap,res@nsnp) + rm(tmp_haplos) + } #selection des haplos d'apres les donnees manquantes - if(min_perc_geno.hap<100){ +# if( !(is.na(min_perc_geno.hap)) ){ cat("Discard Haplotype with less than ",min_perc_geno.hap,"% of genotyped SNPs\n") hap_sel=(100*rowSums(res@haplo!=0)/res@nsnp)>=min_perc_geno.hap if(sum(hap_sel)==res@nhap){ @@ -168,14 +181,14 @@ test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) res@nhap=sum(hap_sel) cat(res@nhap," Haplos remaining\n") } - } - + if(res@nhap==0){stop("No haplotype left after filtering of missing data: check allele coding (e.g., correspondance of allele coding between the map_inp and haplotype input file) data or relax the value of min_perc_geno.hap to allow for more missing data")} +# } #selection des snps d'apres les donnees manquantes - if(min_perc_geno.snp<100){ +# if( !(is.na(min_perc_geno.snp)) ){ cat("Discard SNPs genotyped on less than ",min_perc_geno.snp,"% of haplotypes\n") snp_sel=(100*colSums(res@haplo!=0)/res@nhap)>=min_perc_geno.snp if(sum(snp_sel)==res@nsnp){ - cat("No SNPs discarded\n") + cat("No SNP discarded\n") }else{ cat(res@nsnp-sum(snp_sel)," SNPs discarded\n") res@haplo=res@haplo[,snp_sel] @@ -184,16 +197,17 @@ test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) res@snp.name=res@snp.name[snp_sel] cat(res@nsnp," SNPs remaining\n") } - } + if(res@nsnp==0){stop("No SNP left after filtering of missing data: check allele coding (e.g., correspondance ofallele coding between the map_inp and haplotype input file) data or relax the value of min_perc_geno.snp to allow for more missing data")} + # } #selection des snps sur MAF if(min_maf>0){ cat("Discard SNPs with MAF below ",min_maf,"\n") - tmp_n1=colSums(res@haplo==1) ; tmp_maf=tmp_n1/(tmp_n1 + colSums(res@haplo==2)) - tmp_maf[tmp_maf>0.5]=1-tmp_maf[tmp_maf>0.5] + tmp_n1=colSums(res@haplo==1) ; tmp_n=colSums(res@haplo!=0) + tmp_maf=0.5-abs(0.5-tmp_n1/tmp_n) snp_sel=tmp_maf>min_maf if(sum(snp_sel)==res@nsnp){ - cat("No SNPs discarded\n") + cat("No SNP discarded\n") }else{ cat(res@nsnp-sum(snp_sel)," SNPs discarded\n") res@haplo=res@haplo[,snp_sel] @@ -202,6 +216,7 @@ test_fphase_2=grep("BEGIN COMMAND_LINE",out_fphase) res@snp.name=res@snp.name[snp_sel] cat(res@nsnp," SNPs remaining\n") } + rm(tmp_n1) ; rm(tmp_n) ; rm(tmp_maf) } cat("Data consists of",res@nhap,"haplotypes and",res@nsnp,"SNPs\n") diff --git a/R/distribplot.R b/R/distribplot.R index 572adb5..c4b8a95 100644 --- a/R/distribplot.R +++ b/R/distribplot.R @@ -1,5 +1,16 @@ -distribplot<-function(data,col=c("blue","red"),main="iHS distribution",xlab="iHS"){ - plot(density(data,na.rm=T),main=main,xlab="iHS",col=col[1]) - curve(dnorm,col=col[2],add=T) - legend("right","top",c("Observed","Gaussian"),fill=col) - } +distribplot <- function(data,lty = 1,lwd = 1.5,col = c("blue","red"),main = "Genome-wide distribution",xlab = "",cex.main = 1.5,cex.lab = 1.25,qqplot = TRUE) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(density(data,na.rm = TRUE),main = main,xlab = xlab,col = col[1],lty = lty,lwd = lwd,cex.main = cex.main,cex.lab = cex.lab) + curve(dnorm,col = col[2],add = TRUE) + legend("topright",c("Observed","Gaussian"),bty = "n",col = col,lty = lty,lwd = lwd) + if (qqplot) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + qqnorm(data[!is.na(data)],cex.main = cex.main,cex.lab = cex.lab,pch = 16,cex = 0.75) + abline(a=0,b=1,lty=2) + } + par(mar = c(5,4,4,2) + 0.1) +} diff --git a/R/ies2rsb.R b/R/ies2rsb.R index 60a6d5b..630d10b 100644 --- a/R/ies2rsb.R +++ b/R/ies2rsb.R @@ -1,18 +1,25 @@ -ies2rsb<-function(hh_pop1,hh_pop2,popname1=NA,popname2=NA,method="bilateral"){ - - ies_1=hh_pop1[,6] ; ies_2=hh_pop2[,6] - if(!(nrow(hh_pop1)==nrow(hh_pop2))){stop("hh_pop1 and hh_pop2 must have the same dimensions")} - if(sum(hh_pop1[,2]==hh_pop2[,2])minmaf & res_ihh[,3]<(1-minmaf) , ] - res_ihs=cbind(res_ihh[,1:2],rep(0,nrow(res_ihh))) - colnames(res_ihs)[3]="iHS" ; rownames(res_ihs)=rownames(res_ihh) - if(freqbin>0){ - freq_class=seq(minmaf,1-minmaf,freqbin) - summary_class=matrix(0,length(freq_class)-1,4) ; colnames(summary_class)=c("Freq Class","Size","Mean iHH","SD iHH") - ihs=log(res_ihh[,4]/res_ihh[,5]) ; ihs[ihs=="Inf" | ihs=="-Inf"]=NA - for(c in 1:(length(freq_class)-1)){ - lim_inf=freq_class[c] ; lim_sup=freq_class[c+1] - mrk_sel=(res_ihh[,3]>=lim_inf & res_ihh[,3] minmaf) & (res_ihh$freq_A < (1 - minmaf)),] + if (freqbin > 0) { + freq_class = seq(minmaf,(1 - minmaf),freqbin) + summary_class = matrix(0,length(freq_class) - 1,3) + colnames(summary_class) = c("Number of SNPs","mean of the log(iHHA/iHHD) ratio","sd of the log(iHHA/iHHD) ratio") + tmp.classnames=rep(NA,nrow(summary_class)) + ihs = log(res_ihh$iHH_A / res_ihh$iHH_D) + ihs[ihs == "Inf" | ihs == "-Inf"] = NA + for (c in 1:(length(freq_class) - 1)) { + lim_inf = freq_class[c] + lim_sup = freq_class[c + 1] + mrk_sel = ((res_ihh$freq_A >= lim_inf) & (res_ihh$freq_A < lim_sup)) + bin_size = sum(mrk_sel) + if (bin_size < 10) { + warning(paste("The number of SNPs with allele frequencies comprised between ",lim_inf," and ",lim_sup," is less than 10: you should probably increase freqbin\n",sep="")) + } + tmp.classnames[c]= paste(lim_inf,"-",lim_sup) + summary_class[c,1] = bin_size + summary_class[c,2] = mean(ihs[mrk_sel],na.rm = TRUE) + summary_class[c,3] = sd(ihs[mrk_sel],na.rm = TRUE) + ihs[mrk_sel] = (ihs[mrk_sel] - summary_class[c,2]) / summary_class[c,3] + } + }else { + freq_class = unique(res_ihh$freq_A) + freq_class = freq_class[order(freq_class)] + summary_class = matrix(0,length(freq_class),3) + tmp.classnames=rep(NA,nrow(summary_class)) + colnames(summary_class) = c("Number of SNPs","mean of the iHHA/iHHD log-ratio","sd of the iHHA/iHHD log-ratio") + ihs = log(res_ihh$iHH_A / res_ihh$iHH_D) + for (f in 1:length(freq_class)) { + mrk_sel = (res_ihh$freq_A == freq_class[f]) + tmp.classnames[c] = freq_class[f] + summary_class[f,1] = sum(mrk_sel) + summary_class[f,2] = mean(ihs[mrk_sel],na.rm = TRUE) + summary_class[f,3] = sd(ihs[mrk_sel],na.rm = TRUE) + ihs[mrk_sel] = (ihs[mrk_sel] - summary_class[c,2]) / summary_class[c,3] + } + } + rownames(summary_class)=tmp.classnames + + tmp_pval = -log10(1 - 2 * abs(pnorm(ihs) - 0.5)) + tmp_pval2 = tmp_pval + tmp_pval2[tmp_pval2 == "Inf"] = NA + tmp_pval[tmp_pval == "Inf"] = max(tmp_pval2,na.rm = TRUE) + 1 - return(list(res.ihs=res_ihs,summary.class=summary_class)) + res_ihs = data.frame(res_ihh$CHR,res_ihh$POSITION,ihs,tmp_pval,stringsAsFactors=FALSE,row.names=rownames(res_ihh)) + colnames(res_ihs)=c("CHR","POSITION","iHS","-log10(p-value)") + return(list(iHS = res_ihs,frequency.class = summary_class)) } diff --git a/R/ihsplot.R b/R/ihsplot.R index b949b39..dd39253 100644 --- a/R/ihsplot.R +++ b/R/ihsplot.R @@ -1,20 +1,68 @@ -ihsplot<-function(data,plot.pval="TRUE",ylim.scan=2,pch=16,main="iHS"){ -# if(plot.pval){layout(matrix(1:2,2,1))} - tmp_chr=unique(data[,1]) ; col_chr=1:length(tmp_chr) ; names(col_chr)=tmp_chr ;pos_chr=rep(0,length(tmp_chr)) - tmp_nmrk=table(data[,1]) ; pos_mrk=cumsum(tmp_nmrk) - pos_chr[1]<-floor(pos_mrk[1]/2) - if(length(tmp_chr)>1){for (i in 2:length(tmp_chr)){pos_chr[i]=pos_mrk[i-1] + floor((tmp_nmrk[i]/2))}} - - plot(data[,3],pch=pch,las=1,col=col_chr[as.character(data[,1])],xaxt="n",xlab="Chromosome",ylab="iHS",main=main) - abline(h=ylim.scan,lty=2) ; abline(h=-1*ylim.scan,lty=2) - axis(1,at=pos_chr,labels=tmp_chr,las=1) - - if(plot.pval){ - plot(data[,4],pch=pch,las=1,col=col_chr[as.character(data[,1])],xaxt="n",xlab="Chromosome",main="Pvalue", - ylab=expression("-" * log[10] * "[" ~ "1-2|" * Phi[scriptstyle(italic(iHS))] * "-0.5|" ~ "]")) - abline(h=ylim.scan,lty=2) ; abline(h=-1*ylim.scan,lty=2) - axis(1,at=pos_chr,labels=tmp_chr,las=1) - abline(h=ylim.scan,lty=2) ; abline(h=-1*ylim.scan,lty=2) - } -#layout(matrix(1,1,1)) - } +ihsplot <- function(ihsdata,plot.pval = TRUE,ylim.scan = 2,pch = 16,cex = 0.5,cex.lab = 1.25,main = NA,cex.main = 1.5,cex.axis=1.) { + if(is.null(ihsdata$iHS) | is.null(ihsdata$frequency.class)){stop("The ihsdata list is invalid and was not generated by the ihh2ihs() function...")} + data=ihsdata$iHS +# if (colnames(data)[3] != "iHS") {stop("Unrecognized column name for iHS: the data is not a data frame generated by the ihh2ihs() function...")} + lst_chrm <- unique(data$CHR) + nbr_chrm <- length(lst_chrm) + cum <- rep(0,(nbr_chrm + 1)) + if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) { + cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1) + } + } + cum <- cumsum(cum) + pos <- rep(0,length(data$CHR)) + pos_labels <- rep(0,nbr_chrm) + for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR == lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1]) / 2 + } + col_chr <- data$CHR + if (nbr_chrm > 1) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos,data$iHS,pch = pch,cex = cex,las = 1,col = col_chr,xaxt = "n",xlab = "Chromosome",ylab = expression(italic(iHS)),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + axis(1,at = pos_labels,labels = lst_chrm,las = 1,cex.lab=cex.lab,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + if (plot.pval) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos,data$"-log10(p-value)",pch = pch,cex = cex,las = 1,col = col_chr,xaxt = "n",xlab = "Chromosome",ylab = expression("-"*log[10]*"[1"~"-"~"2"~"|"~Phi[scriptstyle(italic(iHS))]~"-"~0.5*"|]"),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + axis(1,at = pos_labels,labels = lst_chrm,las = 1,cex.lab=cex.lab,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + } + } + else { + if (max(pos) < 1e3) { + scale <- 1 + unit = "(bp)" + } + else if (max(pos) < 1e6) { + scale <- 1e3 + unit = "(kb)" + } + else if (max(pos) < 1e9) { + scale <- 1e6 + unit = "(Mb)" + } + else { + scale <- 1e9 + unit = "(Gb)" + } + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos / scale,data$iHS,pch = pch,col = col_chr,xlab = paste("Position",unit),ylab = expression(italic(iHS)),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + if (plot.pval) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos / scale,data$"-log10(p-value)",pch = pch,col = col_chr,xlab = paste("Position",unit),ylab = expression("-"*log[10]*"[1"~"-"~"2"~"|"~Phi[scriptstyle(italic(iHS))]~"-"~0.5*"|]"),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + } + } + par(mar = c(5,4,4,2) + 0.1) +} diff --git a/R/rsbplot.R b/R/rsbplot.R index a2f097f..965a590 100644 --- a/R/rsbplot.R +++ b/R/rsbplot.R @@ -1,30 +1,76 @@ -rsbplot<-function(data,plot.pval="TRUE",ylim.scan=2,pch=16,main=NA){ - tmp.plot=0 - if(colnames(data)[4]=="Pvalue (bilateral)"){yleg=expression("-" * log[10] * "[" ~ "1-2|" * Phi[scriptstyle(italic(rSB))] * "-0.5|" ~ "]");tmp.plot=1} - if(colnames(data)[4]=="Pvalue (unilateral)"){yleg=expression("-" * log[10] * "[" ~ "1-" * Phi[scriptstyle(italic(rSB))] * "" ~ "]");tmp.plot=1} - if(tmp.plot==0){ - warning("Unrecognized column name for Pvalue: plot.pval has been turned off") - plot.pval="FALSE" - } - - if(is.na(main)){main=colnames(data)[3]} - -# if(plot.pval){layout(matrix(1:2,2,1))} - tmp_chr=unique(data[,1]) ; col_chr=1:length(tmp_chr) ; names(col_chr)=tmp_chr ;pos_chr=rep(0,length(tmp_chr)) - tmp_nmrk=table(data[,1]) ; pos_mrk=cumsum(tmp_nmrk) - pos_chr[1]<-floor(pos_mrk[1]/2) - if(length(tmp_chr)>1){for (i in 2:length(tmp_chr)){pos_chr[i]=pos_mrk[i-1] + floor((tmp_nmrk[i]/2))}} - - plot(data[,3],pch=pch,las=1,col=col_chr[as.character(data[,1])],xaxt="n",xlab="Chromosome",main=main,ylab="rSB") - abline(h=ylim.scan,lty=2) ; abline(h=-1*ylim.scan,lty=2) - axis(1,at=pos_chr,labels=tmp_chr,las=1) - - if(plot.pval){ - plot(data[,4],pch=pch,las=1,col=col_chr[as.character(data[,1])],xaxt="n",xlab="Chromosome",main="Pvalue", - ylab=yleg) - abline(h=ylim.scan,lty=2) ; abline(h=-1*ylim.scan,lty=2) - axis(1,at=pos_chr,labels=tmp_chr,las=1) - abline(h=ylim.scan,lty=2) ; abline(h=-1*ylim.scan,lty=2) - } -#layout(matrix(1,1,1)) - } +rsbplot <- function(data,plot.pval = TRUE,ylim.scan = 2,pch = 16,cex = 0.5,cex.lab = 1.25,main = NA,cex.main = 1.5,cex.axis=1) { + if (!(grepl("Rsb",colnames(data)[3]))) {stop("Unrecognized column name for Rsb: the data is not a matrix generated by the ies2rsb() function...")} + if (colnames(data)[4] == "-log10(p-value) [bilateral]") { + yleg = expression("-"*log[10]*"[1"~"-"~"2"~"|"~Phi[scriptstyle(italic(Rsb))]~"-"~0.5*"|]") + } + else if (colnames(data)[4] == "-log10(p-value) [unilateral]") { + yleg = expression("-"*log[10]*"[1"~"-"~Phi[scriptstyle(italic(Rsb))]*"|]") + } + else { + warning("Unrecognized column name for p-values: plot.pval has been turned off") + plot.pval = FALSE + } + lst_chrm <- unique(data$CHR) + nbr_chrm <- length(lst_chrm) + cum <- rep(0,(nbr_chrm + 1)) + if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) { + cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1) + } + } + cum <- cumsum(cum) + pos <- rep(0,length(data$CHR)) + pos_labels <- rep(0,nbr_chrm) + for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR == lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1]) / 2 + } + col_chr <- data$CHR + if (nbr_chrm > 1) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos,data[,3],pch = pch,cex = cex,las = 1,col = col_chr,xaxt = "n",xlab = "Chromosome",ylab = expression(italic(Rsb)),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + axis(1,at = pos_labels,labels = lst_chrm,las = 1,cex.lab=cex.lab,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + if (plot.pval) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos,data[,4],pch = pch,cex = cex,las = 1,col = col_chr,xaxt = "n",xlab = "Chromosome",ylab = expression(-log[10]~"("*italic(p)*"-value)"),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + axis(1,at = pos_labels,labels = lst_chrm,las = 1,cex.lab=cex.lab,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + } + } + else { + if (max(pos) < 1e3) { + scale <- 1 + unit = "(bp)" + } + else if (max(pos) < 1e6) { + scale <- 1e3 + unit = "(kb)" + } + else if (max(pos) < 1e9) { + scale <- 1e6 + unit = "(Mb)" + } + else { + scale <- 1e9 + unit = "(Gb)" + } + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos / scale,data[,3],pch = pch,col = col_chr,xlab = paste("Position",unit),ylab = expression(italic(Rsb)),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + if (plot.pval) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos / scale,data[,4],pch = pch,col = col_chr,xlab = paste("Position",unit),ylab = expression(-log[10]~"("*italic(p)*"-value)"),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + } + } + par(mar = c(5,4,4,2) + 0.1) +} diff --git a/R/scan_hh.R b/R/scan_hh.R index 4a0538f..080353d 100644 --- a/R/scan_hh.R +++ b/R/scan_hh.R @@ -1,24 +1,35 @@ -scan_hh<-function(haplohh,limhaplo=2,limehh=0.05,limehhs=0.05){ - if(!(is.haplohh(haplohh))){stop("Data oject is not of valid haplohh object... (see data2haplohh() function)")} - if(limhaplo<2){stop("limhaplo must be >1")} - if(limehh<0 | limehh>1){stop("limehh must be between 0 and 1")} - if(limehhs<0 | limehhs>1){stop("limehhs must be between 0 and 1")} - IHH <- matrix(0.0,nrow = haplohh@nsnp,ncol = 2) - IES <- vector(mode = "numeric",length = haplohh@nsnp) - res_scan<-.C("r_scan_hh", - Rdata = as.integer(haplohh@haplo), - number_SNPs = as.integer(haplohh@nsnp), - number_chromosomes = as.integer(haplohh@nhap), - map = as.double(haplohh@position), - IHH = as.double(IHH), - IES = as.double(IES), - min_number_haplotypes = as.integer(limhaplo), - min_EHH = as.double(limehh), - min_EHHS = as.double(limehhs) - ) - tmp_n1=colSums(haplohh@haplo==1) ; tmp_freq=tmp_n1/(tmp_n1 + colSums(haplohh@haplo==2)) - RES_ALL=cbind(rep(haplohh@chr.name,haplohh@nsnp),haplohh@position,tmp_freq,matrix(res_scan$IHH,haplohh@nsnp,2),res_scan$IES) - rownames(RES_ALL)=haplohh@snp.name ; colnames(RES_ALL)=c("CHR","POSITION","FREQ_a","IHHa","IHHd","IES") - return(RES_ALL) - +scan_hh<-function(haplohh,limhaplo = 2,limehh = 0.05,limehhs = 0.05,threads = 1) { + if (!(is.haplohh(haplohh))) {stop("The data are not formatted as a valid haplohh object... (see the data2haplohh() function)")} + if (limhaplo < 2) {stop("limhaplo must be larger than 1")} + if (limehh < 0 | limehh > 1) {stop("limehh must lie between 0 and 1")} + if (limehhs < 0 | limehhs > 1) {stop("limehhs must lie between 0 and 1")} + ihh <- matrix(0.0,nrow = haplohh@nsnp,ncol = 2) + ies_tang <- ies_sabeti <- vector(mode = "numeric",length = haplohh@nsnp) + res_scan <- .C("CALL_SCAN_HH", + Rdata = as.integer(haplohh@haplo), + number_SNPs = as.integer(haplohh@nsnp), + number_chromosomes = as.integer(haplohh@nhap), + min_number_haplotypes = as.integer(limhaplo), + min_EHH = as.double(limehh), + min_EHHS = as.double(limehhs), + map = as.double(haplohh@position), + IHH = as.double(ihh), + IES_TANG = as.double(ies_tang), + IES_SABETI = as.double(ies_sabeti), + number_threads = as.integer(threads) + ) + tmp_n1 = colSums(haplohh@haplo == 1) +# tmp_freq = tmp_n1 / (tmp_n1 + colSums(haplohh@haplo == 2)) +# RES_ALL = cbind(rep(haplohh@chr.name,haplohh@nsnp),haplohh@position,tmp_freq,matrix(res_scan$IHH,haplohh@nsnp,2),res_scan$IES_TANG,res_scan$IES_SABETI) +# rownames(RES_ALL) = haplohh@snp.name +# colnames(RES_ALL) = c("CHR","POSITION","freq_A","iHH_A","iHH_D","iES_Tang_et_al_2007","iES_Sabeti_et_al_2007") + freq_A=tmp_n1 / (tmp_n1 + colSums(haplohh@haplo == 2)) + CHR=rep(haplohh@chr.name,haplohh@nsnp) + POSITION=haplohh@position + tmp.ihh=matrix(res_scan$IHH,haplohh@nsnp,2) + iHH_A=tmp.ihh[,1] + iHH_D=tmp.ihh[,2] + iES_Tang_et_al_2007=res_scan$IES_TANG + iES_Sabeti_et_al_2007=res_scan$IES_SABETI + return(data.frame(CHR,POSITION,freq_A,iHH_A,iHH_D,iES_Tang_et_al_2007,iES_Sabeti_et_al_2007,row.names=haplohh@snp.name,stringsAsFactors=FALSE)) } diff --git a/R/xpehhplot.R b/R/xpehhplot.R new file mode 100644 index 0000000..9f829c9 --- /dev/null +++ b/R/xpehhplot.R @@ -0,0 +1,76 @@ +xpehhplot <- function(data,plot.pval = TRUE,ylim.scan = 2,pch = 16,cex = 0.5,cex.lab = 1.25,main = NA,cex.main = 1.5,cex.axis=1) { + if (!(grepl("XPEHH",colnames(data)[3]))) {stop("Unrecognized column name for XPEHH: the data is not a matrix generated by the ies2xpehh() function...")} + if (colnames(data)[4] == "-log10(p-value) [bilateral]") { + yleg = expression("-"*log[10]*"[1"~"-"~"2"~"|"~Phi[scriptstyle(italic(XPEHH))]~"-"~0.5*"|]") + } + else if (colnames(data)[4] == "-log10(p-value) [unilateral]") { + yleg = expression("-"*log[10]*"[1"~"-"~Phi[scriptstyle(italic(XPEHH))]*"|]") + } + else { + warning("Unrecognized column name for p-values: plot.pval has been turned off") + plot.pval = FALSE + } + lst_chrm <- unique(data$CHR) + nbr_chrm <- length(lst_chrm) + cum <- rep(0,(nbr_chrm + 1)) + if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) { + cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1) + } + } + cum <- cumsum(cum) + pos <- rep(0,length(data$CHR)) + pos_labels <- rep(0,nbr_chrm) + for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR == lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1]) / 2 + } + col_chr <- data$CHR + if (nbr_chrm > 1) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos,data[,3],pch = pch,cex = cex,las = 1,col = col_chr,xaxt = "n",xlab = "Chromosome",ylab = expression(italic(XPEHH)),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + axis(1,at = pos_labels,labels = lst_chrm,las = 1,cex.lab=cex.lab,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + if (plot.pval) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos,data[,4],pch = pch,cex = cex,las = 1,col = col_chr,xaxt = "n",xlab = "Chromosome",ylab = expression(-log[10]~"("*italic(p)*"-value)"),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + axis(1,at = pos_labels,labels = lst_chrm,las = 1,cex.lab=cex.lab,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + } + } + else { + if (max(pos) < 1e3) { + scale <- 1 + unit = "(bp)" + } + else if (max(pos) < 1e6) { + scale <- 1e3 + unit = "(kb)" + } + else if (max(pos) < 1e9) { + scale <- 1e6 + unit = "(Mb)" + } + else { + scale <- 1e9 + unit = "(Gb)" + } + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos / scale,data[,3],pch = pch,col = col_chr,xlab = paste("Position",unit),ylab = expression(italic(XPEHH)),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + if (plot.pval) { + dev.new() + plot.new() + par(mar = c(5,5,4,2) + 0.1) + plot(pos / scale,data[,4],pch = pch,col = col_chr,xlab = paste("Position",unit),ylab = expression(-log[10]~"("*italic(p)*"-value)"),cex.lab = cex.lab,main = main,cex.main = cex.main,cex.axis=cex.axis) + abline(h = c(-ylim.scan,ylim.scan),lty = 2) + } + } + par(mar = c(5,4,4,2) + 0.1) +} diff --git a/build/vignette.rds b/build/vignette.rds new file mode 100644 index 0000000..775b871 Binary files /dev/null and b/build/vignette.rds differ diff --git a/data/haplohh_cgu_bta12.RData b/data/haplohh_cgu_bta12.RData index 245eb6e..2102062 100644 Binary files a/data/haplohh_cgu_bta12.RData and b/data/haplohh_cgu_bta12.RData differ diff --git a/data/wgscan.cgu.RData b/data/wgscan.cgu.RData index 8c6a484..f12ad8b 100644 Binary files a/data/wgscan.cgu.RData and b/data/wgscan.cgu.RData differ diff --git a/data/wgscan.eut.RData b/data/wgscan.eut.RData index 522a445..3058ca2 100644 Binary files a/data/wgscan.eut.RData and b/data/wgscan.eut.RData differ diff --git a/inst/CITATION b/inst/CITATION index 92d0b12..dcd3fd9 100644 --- a/inst/CITATION +++ b/inst/CITATION @@ -5,12 +5,22 @@ vers <- paste("R package version", meta$Version) citEntry(entry="Article", - author = "Gautier, M. and Vitalis, R.", + author = "Gautier M. and Vitalis R.", title = "rehh: An R package to detect footprints of selection in genome-wide SNP data from haplotype structure", journal = "Bioinformatics", year = 2012, + volume = 28, + number = 8, + pages="1176-1177", + textVersion ="Gautier M. and Vitalis R. (2012). rehh: An R package to detect footprints of selection in genome-wide SNP data from haplotype structure. Bioinformatics, 28(8):1176-1177" ) + +citEntry(entry="Article", + author = "Gautier M., Klassmann A., and Vitalis R.", + title = "rehh2.0: an improved version of the R package rehh to identify footprints of selection from haplotype structure", + journal = "Molecular Ecology Resources", + year = 0, volume = 0, - number = 0, - pages="accepted", - textVersion ="Gautier, M. and Vitalis, R. (2012). rehh: An R package to detect footprints of selection in genome-wide SNP data from haplotype structure. Bioinformatics, accepted" ) + number = "submitted", + pages="1176-1177", + textVersion ="Gautier M., Klassmann A., and Vitalis R. (2016). rehh: An R package to detect footprints of selection in genome-wide SNP data from haplotype structure. Molecular Ecology Resources, submitted" ) diff --git a/inst/bta12_cgu.hap b/inst/bta12_cgu.hap index 4b53dfc..b419e16 100644 --- a/inst/bta12_cgu.hap +++ b/inst/bta12_cgu.hap @@ -1,280 +1,280 @@ -1 2 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 1 1 1 1 1 2 1 2 1 2 2 2 2 1 1 1 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 1 1 1 2 1 2 2 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 2 1 1 1 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 2 1 1 1 1 1 1 1 1 1 1 2 2 2 2 1 2 2 2 1 1 1 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 2 1 1 1 2 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 1 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 1 2 1 1 1 2 2 1 2 2 1 2 1 2 1 1 1 1 2 1 2 2 2 1 2 1 2 2 2 1 2 2 1 2 2 2 1 2 1 1 2 1 2 1 2 2 1 2 1 2 2 1 1 2 2 1 2 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 1 2 1 1 1 2 1 2 2 2 1 1 1 2 1 1 1 1 2 2 2 1 1 1 2 2 2 2 2 1 1 1 1 2 1 1 1 2 2 1 1 2 1 2 2 2 1 1 2 2 1 1 1 2 2 2 2 1 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C G T A G C T A C C T A C G A A G G T T G C T T C C A T C C T A G C A A G G A A C C T T C C A T G G A A G C T A C G A T C G A T C G T A G C A A G C A T C C A A G G T T G C T A G C T A G G A T G G A T C C T A G C T A G C T A G G T T G G T A G G T T G G A A G G T A G C A T G C T T G C A A C G A A G G T A C C A A C G A T G G T A G G T T G C T T G C A A G C A A C G T T G G T A C C A A G G A A G G T A G C T T G G T A G G T A G C A A C G A A C C T A C G A A C G A T G C T T C G T A G C T T C G A A C G A A G G A A C C T A C G T A C G A A G C T T G C A T G G T T C G T T C G T A G C A A C C A A G G A T G G A A C G T A G G A A C C T A C C T A G C T A C G A A G G A T G C A T G G T A C G T T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C T T G G T A G C A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A T G C A A C C A A G C T A G G T T C G A T G C T A G C A T C G T T C C T A C C T A G G T A G C T A C G T A C C A T C G A T C C T A C G T A G G T T G G T T G G T T G C A A C C T T G C A A G C A T C C T A C G T T C G A A C C A T G G A T C C T A C G A A G C T A G C A T C G A A G C A A G C T T C C T T G C A A G G A T C G A A C C T A C G A T C G A A G C A T G C A A G G T A G C T T G C T A G C A A C G T A C C A A C C T A G G T A G C A A G G T T G C T T G C T A C C T T G C A T C G A A G C A T C C A T G G T A C G A A G C A T C C T T C G T A G C A A G C T A C G T T C G A A C G T A C C A T G C A T C G A A C C T A C G A A G G T T G C T T C G A T C C T A G G A T C C T A C C T A G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A T G G A T G C T A G G A T G C T A C G A T C G T T C C A T C C T A G C T T G G A T G C T A C C T T G G T T G C T A G G T A G C T T C G T A C G T A C C A A C C A T G C T T C C T T C C T T G C A T C G T A C C A A G C T T G G T A G G A T G G A T G C T A C G A T C C A T C C T T G G A A G C T A G C T T C C T T G G T A G C A A C G A T G C A A G G T T G G A T G G T A C C A T C G A T G C T T G G A T C G A A C G A T C C T T G C A A C G T A G C A T G C T T C C T T C G T T G C A A C G T T C G A A C C T A G G A A C C T T G C T T G C A T G G T A G C T A G C A A G G A A C C T T C G T T C G T T G C T T C C A A C C T A G C A T G C A T C G A A G G A A G G T T C G T A G C A T G C T T C C T A C G T A G C T T G C T A C C T A G C A T G C A A C C A T C C T T G C T A C C T A G G T T C C T A C G T T G C A A G C T T G C T T C C T A C C A T C G A T G C T A C C A A G C A A C C A A G C T A G C T A C C T T G G T +2 A G G T A C G T A C G T A G C T A C C T T G C A A G G T T G G T A C C A A G G A T G G T T G C T T G G A A C G A A G G T T G G T A G C A T G C T T C C T A G C T T G C T A G G A T C G A T C G A A C G T T G C A A G C A T G G T A G G T A G G T A C C A T C C A T C G T T G C A A C C T T C G T A G G T T G C T A C C A T G C T A G C A A G G A T C C T T C C A T G G A A G C T A C C A T C G T T C G T T G G T A G C A A G C A A G G T T G C T A C C T A G C A A G C T T G C A A G G T A G C T A G G T T C C T A C C A T C C A T G C A A C C T T C G T A C G A A C G A A G G T T G C T A C G A A G G T A G G T T G C T T G C T T G C A T C C A T G C A A C C A A G G A T C C T A G C T T C G A A G C A T G C A A G C A A G G A A C G A A C G T T C C A A C G T A C C T T C C A A G G A A G C A A C C T T C G T T C G T T C C T T G C A T G G T T C C T T C G T A C C A T G G A A G G A T G G A A G G A T C G A A C C A T C C T A G G T A C G A A G C T A G C A T G G A A C C A T G C A A C G T T G G A T G C T T G G T A C C T T G G A A G G T A G C T T G G A A C G T A G C T A G C A A G C T A G G A A G G T A C C A T C G T A C C A A C G T A C C T T C G T T C G T T G C A A G G T A G G T T G C T T G C A T C C T T G C T A C C A A G C A T G C A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T A G G T T G G A T G G T A G C A T G G T T C C A T G G A A G C T A C C A T G C A A C C A A G C T A G C T A G C T T C C A T G G A A C C T T C C A T C C A A G C A T G G A A G G T T C C T T G C T A C G A T C C T A C C T A C C A A G G T A C C A T C C T T G C T T C C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G T A C C T A G C A T G G T T G C T A G C A A C C A A G G A T G C T T C C T T C G A A C C A T G C T T C G T A G G T T G C A A C G T T C G T A G G A T C C T A C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G A A G C T T G C T T G C A A C G T T G C A A G G T T G C T A G G T A C G T T C G A A G C T A C C T T G G T T C C A T G C A T G G T T G C A A C C T A C G T A G C T A C G A T G G T A C C A T C C A T C G A A C G A A G C T A C C T T G G T T C C T T G C A A G C A T G C A A G C A T G C A T G G T A C G A T C C T T G G A A C C A A G G A A C G A T C C T T G C A T C G T A C G A A C C T A G C T T G G A T G C A T G G T T C G A A C C T T C G T T G G A A C C A A C G T T G C A A G C T T G C A A G G T A C C T A C C T T G G A T G C A A G C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T T G G A T G G T T C C T A C G T A G G T A C C A A C C T T G C T T G G A A C C A T G C T T C C A A C C A A C C T A C C T T C C T T G C T A G G T T G G T T C C T A G C T A C G T A G C T T G G A A G G A A C C T A G C T A G C A A C G T A C C T +3 T G C T A C G T A C G T T G C T A C C T T C C A A G G A A C G A A C C A A G G T T G C T T G C T T G G A A G G A T G C T T G G T T G G A A C C A T G C A A C C T T G G A T C C A T C C A T G G A A C G T T G C T T C C T T G C T A G C A A G C A A G C T T G C A A C G T T G C A A C C T A C G A A G G T T C C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A G G A A G G T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G G A A C G T T C C T T G C T A G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G C T T C G A A C G A T G G A A G G A T G G T T G C T T G C A T C C A T G C A A C C A A G G A A C G T T G C A T C G A A G G T A G G A A C G T T G C T A C G T T G G A T C C T T C C T A C C T T G G T T C G A A G G T T C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A C C A T G G T A C C A T G C A A C G T T C C A T G C T T C C T A G C A A C C A T C G T A C C T T G G T A C C T A G C T A G C T A G C A T C G A A G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A A G C A A C C A A C G T A G C A A G C T A C C T A G C A T G G T T G C T A G G A A G G T A G C A T C G A T G G A T C G A T C C T T C C T A G G T A C G T A G G T A G C A A G C T T G C A T C C A T C G T T C C T T G C A A G G A T G G A A C C A T G G A A G G T T G C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G A A C C T T C C T A G G A A G C A A C C A A G C T A G C T A C C T A C G A A G C T A G C T T G G T T C C A A C G A A G C A T C C T A C G T A G C A A G C T A G G T A C G A T C G T A C C A T G C T T C G A T C C T A C G A A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G A A G G T A G G T A C C A A G C T T C C T A G G A T G C A T C G T A G G A T C G T T G G A A G G A T G G A T C C T A G G A A G C T T G C T A G C A A C G T T G C T A C C A T G C A A G G T A C G T A G G A T G C T T G C A T G G T A C C A T G C A A G C A A C C A A C C T T G C T T G G A T G G T A G G T A C C T T C C T A C C T T G G A A C G A A C C T A G C T T G G T A G G T A C C A A C G T T C C T T G G T T G G T A G G A A C G A A C G T T C G T T C G T A C G A T C C T A G C A A C G T A G C A A G C A T G G T T G G A T C C A A G C A A C G T T G G T T C G A A C C T T G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A G C A T C C A T C G A A G C T T G C T T G C A T G G A T G G T T G C T A C G T A G G A A C C T A G C T T G C T T G G A A G C T A C C T T C C A A C C A T C G T T G C A T C C T T G G A A G C T T G C T T C C T A G C A A C G T A G C A T G C A A G C A T C C T A G C T A G C A A C G T A C C T +4 A C C T A G G T T C C T A G C T A C C T T G C T A G G A A C G T T C C A A G G A T C C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A C C A A G G A T C C A T C C A T G G A A C G A T G C T A C C A T C C T A C C A A G G A A C G A T C C T A C G T T G C A A G C T T C C T T G C T T C C T A C C A T C C T A G C A A G G A T C C T T C C A T G G A A G C T A C G A A G C T T C G T A G C T A C G A T G C A A G G T T G C A A G C T A G C A A C C T T G C A A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T C G A T G G T A G G T A C C A A C G A T G G T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T T G C A A G G T A G G A A C G T A C G A T G C T A C C T A C G T A C G A A G G T T C C A A C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C T A G G T A G C A T C C T A G G T A C C T T G G A A C C A A G G A A G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C A T C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A T C C A A C C A A G G A A C C A A G G T T C C T T G C A T C G T T C C T A G G A A G G A A C C T T G G T T G C T T C G A T C C T T G C T A G C A A C G T A G C A A G C T A G G T T G G T A C C T T C C T T G G A T G C A A G G T T G C A T C C A T C G A A C G A T G C A T C G A A G C A A G C T A G G T A G C T T C G T T C C A A C C T A C G T A C C A T C C T T G G A A G C T T C C A A G C T A C G A A C G T T C C T A G G T T G C T A C C A T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G C A A C C A A G G T A G C T A G G T A G C A A G C T A C C T T C C T A G G T A C G T T G C T A C G A T C C T A C G T A G G T T G C A A G G A T C C T T C C A A C G T T C C A T G C T T C C A T G G A A C C T A G G A A C G A A C C T A C C T A C G A T G C A T C G T A G G T A G C A T G G A T C C T T C G T T C C T T C G T A G G T T G C T T G G T T G G T T G C T T C C T T G C T A G G T A C G T A C C T A G C T A G C A T C C T T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A G G T A C C A T C C T T G G A A C G A A G C T A G C T A G G T T C C T T C C A A C C A T G C A T G G T T G C A T G G T A G G A A G G A T G G A T C C A A G G A T G G T T C C T T C C T A C C A T C G A T G G T A G G T T C G T T G G A A G C T A C G T T G G A A G C T T C C T A G C A A C C T A G G A A C C T A G C A A G G A A C C T A C G A T C G A A G C T A C G A T C C T A G C A T C G A A G G A A G C T A G C T T C C A A G G A T G G A T C C T A C G A A G G T A C C T A G C A A G C A T C G T A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G C T T G C T T G C T A C C T A G G T A C C A A G C A A C G T A G G T A G G T T G C T A G G T +5 A G C T A C G T A C G T T G C T A C C T T G C T A G G T A C G A A C G A A G G T T G C T T G C T T G G A A C G A A C C A A C C T A C C T A C C T T G C T A C C T T G G T A C C A A G C A T C G T T G C T T G C T T C C A T C C A A C C A A G C A A G C A T G G A A C G T T G C A A C C T T C G A A C G T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A A G G A A G C T A G C T T G G T A G C T T G C A A G C T A G G A T G C T A C C T A G C A A G C T T G C T A G G T A G C T A G G T T G G T A G G T T C C T T G G T A C G T T G C T A C G A A C C T A G C A T C G A A C G A A G G T A G G A T G C T A G G T T G C A A C C A T C C A A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C C T T G C T A G C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T C G T A C C A A C G A A G G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T A G C T T G G A T C C T T G C T A G C A A C G T A C G A A G C T A G G T T G C A T G C A T C G T T G G T T G C A A C C A T G G A A C C A T G G A T C G A T G C A T C G A A G C A A C C T T G C A A G G A A G G T A G C T A G G A A C G A T C G T T G G A T G G T A G C A A G C T T G G T T C G A A C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C A A C G A A G C T T G G T A C C T T G C T T G C A T C C T A C G T A C G A A G C T A G G A T C C T A G G A T C C T A C C T A G C A T C G T A G G A A C G T A G G T A C C T A G G T A C C T A C G A T G G A T G G T A G G A T G C T T C G A A C C T T C G T T G C T A G C T A G G A T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C A A G G T T G G T T C G A A C C T A G C A A C C A A G C T A G C A A C C T T G G T A G C T A C C A T G C A T G G T T G C T T G G T A C G A T C C A A G C A T G G T A G G A T G G T T C C T T C C A A C G T T G G T A C C T A G G T T G G A T G C T T G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G A A G C T A G G A A G G T T C G T A C C A T C G T A G C T T C C T A C C T A C C A T C C A T C G A T C C A T G G T T C C T A G C A T G C T A G C T A C G T T G G T A C C T A G C A A G C A T G G T A G G A A C G A T C C T T C G T A G G T T G C T A C C T T G C A A G G T T G C T T G C T T G G A T C G A T G C T A G C T A G G T A C C T A G G T T G C A A C C A A C G T +6 A C C T A C G T A C C T T C C T A C C T T G G T A G G A A C G A A C C A A G G T T C C T T G C A T G G A A G G A A G C T T G G T A G C T T C C A T C C T A C C T A G G T A G C A T G C T T G G A A G G T T G G T T C C T T G C T A C C A A C G T A C C A T G G T T C G T T G G T A G C A T C G A A G C T T C C T T G C T T G C A A G C T T C C A T G C A T C C A T G G A A G G A A C C A A G C T T C G T A C G A T G C A A C G A A G G T A G C T A G C T A G G A A C G A T G C A A G G A A C G T A G G A T G G T A G C T T C C T A G G T A G G T T G C T T G C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C T T C C A A G G T A C G T A G G T A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C C T A G G A A G G A A C C T A G C A T G C T T C C T T C C A T G G T T G G A A G C A A G C A T C G A A G C A T C G A T C C A A C C A A G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A G G T A G C T T G G T A G C A A C C A A C C A A C G A A G G T A C C A A C C A A C C A T C C A A G C T A C C A T G G A A G C A T C G T T C C A A C G A T C G A T C C T T G G T A G C A A G C T A C G A A G C A A G G T A C G T T G C T T C G A A C C T T C G A A G G T T G C A A G G A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T A G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C C T T G G T T G C T T C G A A C G T T G G A T G C A T G C A T G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G C T A C C T A G C T A C C T A G G A A C C A T G C A A G G T T G C A A G G T A G G A A G C A A G C A T G G A T C G A A G G A T C C T T C C T A C G T T C G A A G C A A G G T T C G T T G C A A G C T A C G T T G C T T C G A A C C T T G G T A C G A T G G A A G C T A C C A A G G A A C G A A C C T T C G T A G C T A C C T A C C T A G C A T C G A T C G A T G C A T G G T T G C T A G C A T G C T A G C T A C G A T G G T T C C T A C G A T G C T T G G A A G C A T G C A T C C T A C C T A G G T T G C T A C G T A C C T A G G T T G C T T C C T T G C A T C G A A G C T A C C A A G C A A G C T A G G T A G G A A G G T A C C T +7 T G C T A G G A T G C T A G C T A C C T T C G A A G G A A C G T A C C A A G G T T C C T T G C T T G G T T G G A A C C T A G G T A G C A T C C A A C G T A G C A T G G T T G C A T G C T T G G A A C G A T C C T A G C A A C G T A G G T A G G A A C C A T C C T T C G A T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C T A G C T A G C T A C C A A C G A T G C A A G C A A G G A T G C A A C C T A G C T A G C T T G G A A G C T A G C T A G G T T G G T T G G T T G G T T G G T A C C A T G C T T G G A T G G T A G G T T C C A A C G A T G C T A C G A A G C T T G G T T G C A A G C A T G C T A C G A A C G T A C C T A G C T A C C T A C G T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G G T T C C T T C C A T C G T T C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A C G T A G C A T G G T A G G T A G G A A G C T A G C T A C C T T G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C A A G G T A C G T T G G T A C C A A C G T A C G T A C C A A G C T T C G T T C C A T C C A A C G A A G C A A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A C G A T G G T A C G T T G G T A G C T T C C T T G G T T G G T A G G A A G G A A C C T A C G A T C G A T G C T T C C A A C C T A G C A A G C A T G C T T C G T T C G A T C C T T C C A T C G A T G C A T G G A A C C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A C C T A C G T A G C A A G C T A G G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G G T T G G A A C G A A C C T A C C T A C G A T G G T T C G T A G C A T G G A T G G A T C C T T C G A A G C A T G G A A G G A T G C T A G G A T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G C T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T A G G A A C C T A G C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C G A T C C T T G C A A G G T A G C T A G C A T C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C T A G C A A G C T A G C T T C C A T C G T A G C T A C G T T C C T A G C A T G C A T C G A A G C A A G G T A C C A T G C A T G C T T C C T A C C A A G G A T G C T A C C A T C C T T G G A A G C T A C C T A G C A A C C A A C C T T G C T T C C T T C C A A G C T T G C T T G C T A G C A A C C T A G C A A C C T A G G T T G C T A G C A T G C A A C C A A C G T +8 A G G T A C C T A C G A T G C T A C C T T G C T A G G T A G G T A C G A A G G T T C C T T G C T T G G A T G G A T G C T A G G T A G C T T G C T T G C T T G C T T G G T A G C A T G C A T G G T T G G T T G C A A G C A T C G T A C C A A G G A A G C A T G G A A C G T T G C A A C C T T C G T A C C T T G C T A C C A T C C T A G C T T C C A T G C A T C G A T C G T A G C T A C G A A G C T T C G T A G G A A G C A A C C A A G G T T G C T A G C T A G C A A G C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G C T T G C T T G C T T C C A T C C A A C C A A C G T T G G T A C G A A C C T A C G T A C C A A G C T T G G A A C G A A C G A T C C A A C G T A G C T T C C T A C G T A G C A A G G T T C G T A G G A A G C T T G C A T G G T T G C A T G G A A C C A T C G T A G C A A G G A T G G T T C G A A C C A T C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T T C C T T C G T T G G T A C C A A G C A T C G A A C C A A C G A A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T T C G T A G G T T C G A T C C T T G C T A G G T A C C T T G C A A G G A A C C T T G G T T G C A T C C T T C C A T G C A A C G A A G C A A C C A T G G A A G G T T C C A T C C A A G C A A C C A A G C A T G C T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C T T G C T A C G A T C C A A C C T T G G A A G G T A C C T T G C T T C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A C C T T G C A A C C A A G C T T C G A A G G A A G G T A C C A A G C A T C G A T C G A A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A G C T A G G T A G C A A G C T T C C T A C G A T G C A T C G T A G G A T C G T T G G A A G C T T C G T A G C T T C G A A G G T T G C T T G C A A C G A T C C A T G G T A G G T A G G T A C G T T C G A A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A C G T A G C T A G G T T C G T A C C A T C C T T C G T A G G A A G C T A G C A A C C T T G G T A G C A T C C A A C G T T C C T T G G A T G G T A G G A T C G A A C C T T G G T A G C A A C C A T C C T T G C A T G C A T G C T A C C T A G C T T G G A T G C A A G C T A C C T A G G T A C G T T C C T A G G T A G C A T G C A A G C T A G C A A G G A A G C T A C C A T C C T T G C T A C G T T C C A A C G T A C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G A T G C T T G C A A C G A T G C T T C G A A C C A T C C T A G C A A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A T G C A T C C T A G C A T G C A A G C T A C G T +9 A G C T T G G A T G C T T C C T A C C T T C G A A G G A A C G T A C C A A G G T T G C T T G C T T G G T T G G A A G C T T G G T A G C A A C C T T G C A A C C T T G C T A G C A T C G A T G G T T C G T T G C A A G C T T G C T A C G T A G G T A G C A T G C T A C G T T G C A A C C T T C G A T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A C C A T C G T T C C A A G C T A C C A A C C A A G G T T G C T A G C T A G G A A C C T T G C A A G C T A G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G G T T C C T A G G T T G C T A G C T T G C T A G G T A C C A A C G T T G G T A G G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C C A A C C A A G G A A G G A T C G A A G C T A C C T A G G A A G G A A G C T A G C A T C G A T C C A T G C A A C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A G G T A G G A A G C A A G C T A G G T T C C A T G G A T C G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T A C C A A C C A A C G A A C C T A G C T A C C T A G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T G C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T T C C A T C C T T C C A T G C A A C C A A G C A A C C T A C G T A G C T T G C A T C G A A G C A A G C T A G C A A C C T T C C T A G C A A C C T A C G T A C C A T C C T T G G A T G C T T C C A A C G T A C G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G A A C G T T G C T A C G A A C C A A G G A T G C T T G C T T C G A A C C A T G G A A G G A T G G T A C C A A G G T T C C T A G G A A C C A T C G T A G G A T C G T T G C A T C C T T C G A T G C A T C G A A G G A T G C T A C C A A G G A T G C A A G G T T G C T A G G T A C G T A C C T A C C T T G C A T G C T T C C T T G C A T C C T A C C A A C C T T G C T A G C A A G G T T G C T T C G A T C C T T C G A A G G A A G C T A G C T A G G T T G G T A G G T A C C A T G C T T C G T T G G T T C G T A G G A T G C A A C G T T G G T T C G T A C C A T C C T T C C T A C G T T C C T A G C A T G C T T G G A T C G A A G C T A C C T A G C T A G G T T C C T A G G T A G C T T G C A A G C T T G G A A G G A A G C T A C C A T C G T T G C T T C C T A C C T A C G A T C C A T C C A T G C T T G G A T G C T A C G A T G C T A G C T A C G A A G G A T G C T A C C A T G C T T G G A A G G A T C C T T G C A A C C A A G G T A C C T A C G T T G C A A G C T T G C T T G C T A G C T A C G T A G C A T C C A A G C A A C G T A G G T A G C A A G C T A C G T +10 A C C T T G G A T G C T T G C T A G C T A G C T A G C T A G C T A C G A A G G T T G C T T G C T T G G T T C G A T G C A T G G T A G C A T G C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A C G T A G G A A C C A A G C T A C G A T G C T A G C T T C C T T G C T T C C T T C C A T C C A A G C T T C C A A C C A T C C T T G G A T G C T T G C T T C G T A C G T A C C A A C C A A G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A C G T A G G T T C C T A G C T T C C A T G G T A C G T A G C T T G G A A C G A A G G T A C C A A C G A T G G A A G G A T G C T T C C T T G C T T C C A T G C A A C C A A G G A T C C T A G C T T C G A A G G T A C C A A C C T A G G A T C G A A C G A T G C A T C C T A G G T T C C A A G G A T C C A T C C T T G G T T G G A A G C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A A G C A T C G A A C C A T C C T A G G T T G G A A G C A T C C A T C G T A C C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G C T T G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A C C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T T G C A T C G T A G C A T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G G T T G C A T G C A T C G T T G G T T G C A A C C A T G G A A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C T A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T A C C A A G G T A G C T A G C T T G C T T C C A A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A G C A A C G A A C C A A C C T A C G A A G C T A G G T A C C A A C C T T G C A T C C T A C G T A C G T T G C T A G G A A C C T A G G A T C C T A C C A T G C T T C C A T G C T T C C T A G G T A C C A A G C T A C C T A G G A T G G A T C G T A G G A T C G T T G G A T C C T T C G T A C C T A G G A A G G A T G C T A G C A A C G A T C C A T G G T T G C T A G G A A C G T T C C T A C C T A C C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G A A C G T A G C A T C C A T C G A A G G T A G G A A C C T A G C T A C C T T C C A T C C A T G C A T G G T T G G A T G G T A G G A T G C T T C G A T C G A A G G T T G G T T C C T T C C A A G C A T C C T A G C T A G C T T G G A T G C A T G C A A G G T A C G A A G C T T C C A T C C A A G G T A G C A A G C T T G C A A G C A A C G A A C C T A C G T A C C T A G C A A C C T A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A A C G A A C G A T G C T T G C A A C C T T C C T T G G A T G C T T C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G G A T C C T A G C A T C C T A G C T T G C A A G C A A G C T A G C A A G C T A C G T A C G T +11 A C C T A G G T T C C T T G C A A G G A T G C T A G G T A C G A T C C T A C G A T C C T T G C T A C C T T C G A T C C T A G G T A G C T A C C T T G C T A G C T T G G T T G C A A C G A T G G T T C G T T G C T A G C A T C G T A C C T A G G A A C C A T C C A T C G A T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A A G G A T G G T T C C T A C G A A G C T A C C A T C G T T C C A A G G T A C C A A C G A A G C T T G C T A C C T A C C A A C G T T C C T A G G T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G C A T G G T A G C T A C C A A C G A A G C T A G G A T G C T T G C T T G C A A G C A T C C T A C G A A C G T T G G T A C G A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A C C T A C C A T C C A A G G A A G C A A G G T T G G T A C G A A G C T A G C A T G G T A G C A T G G A A C C A A G G A A C C A A G G A A G G T T G C A A G C T A C C T A G C T A C G A A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T T G G T A G C T T G G A A G G T A G C A T G G A A G C T A G G A A G G T T G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C A T G G A T G C A T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G T A G C T T G G A T C C T A G C T A G C T A C C T A G C A A G G A A G C T T G C A T C C A T C C T A C G T T C G A A C G A A G C A A C C T A C G A T C G A T G C A T G C A A C C A A G C T A G C T T G C T T C G T T C C T T C C T T C G A T C C A T C C A T G G A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T A C C T T G C A A C G A T G G T A G G T A C G T A C C A A C C T T C C T T C G A A G C T A C G T T G C T T C G A T C C T A C G A T G C T T G C T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T T C G T T G G A A C C A T C C T T C C T A C G A T G G A T C G T A G C A T C G T T G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A A G G A A C C T T C G A T C G A A C G T T C C T A G G T A G C T A G G T T C G T A C C A T C C T T C G A T G C T T G C T A G C A A G C T T G G T T G G A A C G A A C G T T G G T T G G A T G G T A G G A T G C T T G G A A C C A A G G T A G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G C T T C C T A G C T A G G T T C G T A G C T T G C T T G C A A G C T A C C A A G C A A G G A T C G T T C G T T G C T A G C A A C C T A G G A T G C A T C G A A G C T A G C T T C C A A G C A T G G T T C C T A C C T T C C A A C C T A G C T T G C T A G C A A C C A T C C T A G G T A C C A T C C T T G C T A C C T T G C A T G C T T G C T T G C T A G C A A C G T A G C A T G C A A G C A A C C T A G C T A G C A A G C T A C G T +12 A C C T A C G T A C G T T G C T A C C T A G C T A G G T A G C T A G G A A G G T T C C T T G C T T G G T T C G A A G C A A C C A T G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G A A C G A T C G T A G C A A C G T T G C T A G G T A G G A T G C A A C G T T G C A A G C T A C G A T G C T T G C A T C C A T C C A A G C T T C C A T G C A T C C A A G G A A G C T A C C A A G C T T C C A A G C T T G C A A G C A A C G T T G C A A C C T A G C T A C C T T G C A A G C T A G C T A G G T T C C T A G C T A G G T A C G T A C C A T C C T T G C A A G G T A G G T A C C A A C C A A G G T A G G T T G C T T G C T T G C A A C C A T C C T A C C A A C G T T G G T A C G A A C G A A G G T A C C A A G C A T C G A A G G T A C G T T G C A T C G T A G C T T C G T A C G T A G G A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T C C T A G C A A C C A A G G T A C C T T G G A A G C A A G G A A G G T T G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C T A G G A T G C A T C C T A C G A A G C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C A T C G A T G G T T G G A T C C T T G C T A G C A A C G T A G C A A G G T A C C T T G C A T G C A T C G T T C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A T C C T A C G A T C G T A G C A A G C A T C C T A G C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A T G G T A G G T A C G A A C C A T G C T T C G A A G G A A C G T A C C A T G G A T C G A A C C T A G G A T G G A A G C T A G C A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A C C T T C C T A C C T A C G A T C C T A G G A T G C T A C G A T C G A T C G T A G C T A C G T A G C T T G C T A G C T T G G A T G C A A G G T A G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C A T G C A T G G T T G C T T C C T A C G T A G C T A G G T T C C T A C C A T C C T T C G A A G G A A G C T A C C T T G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C T A C C T T C G T A G G A T C G T T C G T T C C T A G C A T C C A T C C T A G C A T G G A T G C A A G C A A C G T T G G T T C G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C C T T G C A A C G T A C C T A C G T T C C A T C G A T G C T A G G A T G C T A G G A T G G A T C G T A C G A T G C T T G C A A C G T T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T T G C A A C C T A G C A T G G T A C C T T G C T A G C T A G C A A C G T A C C T +13 A C C T A C G T A C C T T G C T A G G A T G C T A G G T A C G A T C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T A G C T A G C T T G C A T C G T A C G T T G C A A G C T T G C T A C C A A C G A A G G A T G C A A C G T T G C A A C C T A C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C T T C C A T G G A T G C T T C G A A G C T T G G T A G C A T G G A T G C A A G G T T G C A A G C T A G C T A C C T T C C A A G C T A G C T A G G T T G G T A G G T A G G A T G C T A C C A T C C T T C C A A G G T A G G T A C C A A C C A A G G T A G G T T G C T T C C T T G G A A C C A T C C A A C C A A C G T T G G T A C G T A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A G C T A C C T T C G A A G G A A G C A A G G T T G G T A C G A A G C T A G C A T G G T A G C A T G G A A C C A A G G A A C C A A G G A A G G T T G C A A G C T A C C T A G C T A C G A A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C A T C G A A G G T A G C A A G C T T C G A T G G T A C C T T G C A T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G G A T G C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G G A A C C T A G G A T G C T T G G T A G C A T C G A T C C T T G C T A G C A T G C T T G C A A G C T A G C T T G C A T G C A T C C T T C C A T G G T A G C A T G G A A C C A T G G A T G G A T G G A T C G A A G C A A G C T T C C T T G C T T C G T T G C A A C C T A C G A T C C A T G C T T G C A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A G G T A G C A A G C T A C G A A G C T A C G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G C A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T T C C T A C C T A C G A T C G T A G G A T G G A T G G A T C C T T C G T A G C T A C G A A G G A T G C T A C G A T G G T A C C A A G G T A G C T T G G T A C G T T G G A T G C T A G C A T G G A A C C T T G C A T G G T T G C T T G C T A C G T T G C A A G G T T C G T T G C A T C C A T G C T A G C T T G G A A C C A T G C A A C G T A G C A A C G A T G C A A G G T A G C A T G G T A G G A T G C T A C G T T G G A A G G A A G G T T G C T T C C T A C G T A G C T A G C A T G G A T C G T T C C A A G C A T C C T A G G A A G C T T C C T T G G T A G G T A C G T A G G T A G C A A G G A A G C T T C C A T C G T T G C A A C C A A C C A A G C A T C G A T C G A A G C A T C G A T C G T A G G A A G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C A T C C A T C C T T C C T T G G T T G C A A G C T T G G T T G C T A G C A T C C T A G C T A C C A A G C A A C C T A G G T A G C T A C G T A C G T +14 A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G C A A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C T T G C A T G G T A G C T T C C A T G G A A C C T T G C A A G C A T C C T A C G T A G G A T G G A T C G A T C G A T G C A A G C T T C G A A G G T T G G T T G C A A C C T A G C A T G C A T G G T T C C T T G G T A G C T A C C T A G C T T G G T A G C T T G C A T G C T A G G A T G C A A C C T A G C T A G C T T G C T A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G T A C G T A G G A A G C A A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A A G C A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G C A A G G A A C C A T C G A A C C A T C C T A G G T T G G A A G C A A C C A T G G T A C C A A C C A A C G T T G C A T G C T A G C T A G C A T C G A A G G T A C G A T G C A A C G T A G G A A G C T A G C A A C C T A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T A C G T T G G T A G G A A G C A A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C T A G G T T C G A T C G A A C G T A C C A T C C A A G C A T G G A A G G T A C C T T G C T A C G A A C C T A C C T T C C A A G G T A G C A A C C T T G C T T G C A A C C T A G C A T C G A A G C T A C C T T G C A A C C A A G G T A C C T A G G T A C C A A G C T T G G A A C G T A G C T A C G T T G C A T C G A A C C T A C G A T G G A A G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T T G G T A G C A A G C T T C G T A G G A T G G A T C G T A G G A T C G T T G G A T C C T T C G T T G C T T C G T A G G T T G C T T G G T T G G A T G C A A G G T T G C T T G G T A C G T T G G A T G C T A G C T A C C T T C C T T G C A T G G T T G C T T C C T A C G T A G C T A C C T A C G T A C C A T C C T T C G A A C G A A G G T A G C T A G C T T C C T T G G A A C C A T C G T T C C T T G G A T G G T A G G A A G G A T G G T T C G T A G G A T G G T T C C T T G C A A C G T T C C A A C C T A C C T T C G T T G G A A G C T T C C T A G C T A G G T T C C T T G G T A G G T A G G T A G C T A G G A A G G A A C C T A C C T T C G T A C C T A C C T A C C T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C C T A C G A A G G A T G C T A C G A T G C T T G G A A G C T A C G T A G C A T C C A T C G T T G C T T G G T T G C A A G C T T G G T T G C T T G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +15 A G G A A C G T A C C T A G C A T G C T T G C T T G G T A C G T T C C T A C G A A G G A A G G T A C G T T C C T A G C T A C C A T G C A T C G A T G C T A C C T T G G T A G C A T G C A T G G A T C C T T G C T T C C T T C G T A C C T A G G A A G C T T G C A A C G A T G C A A G C T A C C T T G G T T G G T T C C A T C C T A G C A T G C A T G G T T C C T T G G A T G C T A C G A A G C T T G G T A G C A T G G A T G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G G T T G C T A C C T T C C T A G G T A G G T T G C T A C G T A C C T A G C A T C G A A C G A T G G T A G G A T G G T T G C T T G C A A G C A T C C T A C G A A C G T A G G T A C G A A C C T A C G T A C C A A G C T A G G A A G C T T C C A T G C A A C G T A G C T A C G T A C G T A G G A A C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G C A T G G T A C G T A G C T T C C T A G G T A G C A T C G T A C G T A G C A T G G T A G C T A G G T T G C T T C C A A C C A T C C T A G C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A T G C A T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T T G C T A G C A A C G T A G C A A G G T A G C T T G C A T G C A T C C T A C G T T G G A A G G A A C G A A C C T A C G A T C G A T G C A T G C A A C C A A G C T A G C T T G C T T C G T T C C T T C C T T C G A T C C A T C C A T G G A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C G T A G C A T C G T A C G A T C C T T C G A A G C A T G G A A G G A T G C T A G G A A C G T T G C T A G G T A G G T A G G T A C G T T C G A A G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A C G A T G C A A G G T T G C A A G G A A G G A T C C T A G G A A C C T A G C A A C G T T C C T T G C A T C G T T G G A A C C T A G C A T G G A T G C A A G C T A C G T A G C T T C G A A C C T T G G T A G C T T C G T A G C A T G C A A G G A A C C T A C C A T C G T T G C A A C G T A C C T A C G A T G C A T C C A T G C A T C G A T G G T A G C A T G C T A G C T A C G A A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +16 T G C A A C G T A C C T T C C T A C C T A G C T A G G T A C G T T C C A A G G A A G G A T G C T A C G T T C G A A C G T T G G T A G C A T G C A T C C T A G C T T G C T A G C A T G C T T G G A T C C T T G C T A C C A T C G T A C C T A G G A A G C T T G C A A C G T T G C A A G C T A C G A A G C T T G C A T C C A T C C T A G C T T C C A T G G T T C C T A C G A A G C T A C C A T C G T T C C A A G G T A C C A A C G A A G G A T G C T A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G C A T G G A A G G T T C C A A C G A A G G T A G G T T G C T T G C T T G C A A C C A T C C T A C C A A C G T T G G T A C G A A C G A A G G T A C C A A C G T A G G A A C C T A C G A T G C T A G C A A G C T T C C A A G G A T C C A A C C T T G G T A C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A A C C A A C G T T G C T T C C T T G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G T A G C T A G C A A C C T T G G A A G C A A G G A T C C A A G G T A C G T T G C T A C G T T G C T A C G A A C C T A G C T A C C A T C G T A G G T A C C A A G G A T C G T A C C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A C C T A G C T T G C T A G C A A G G T A G C T T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C A A G C A T G C T A C G T A C G A T C G T A G C T A C G A T G C A A C G A T G G T T G C T A C G T A G C A A G C T A C G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T C C T A G G T A C G T A C C T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T T G C T T G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C G A A C G T A C C T A C G T A G C A A G G T T G G T T C C A T C C T A G C A A G C A T G C T A C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T G G A A C C A A G G T A G G T A G C T T C G T A C G T T C C T A C C A T G C T T G C T A G G A A G C T A C C A A G G T A C G T T G G T T G C A A G G T A G C A A G C A A G G A T C C A A G C T T C C A T C G T T G C A A C C T A C C T A C G A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C G A A C G A T G C T T C C A A C G T T G C T T G G A A G C A T C C A T C C A A C G A A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G C T A C G T A G G T A G G A A G G T A C C T +17 A G C T A G G T T C G T A G C T A C C T T G C A A G G T A G G T T C C T A G G A T C C T T G C T A C C T T C G A T C C T A C C T A G C T A C C T T G C T A C C A T G G A T C C A T C C A T G G A A G G A T G C T T C C T T C C A T G C T A G G A A C C T T G G A A C C T T G C A A C C T T C G A A G G T T G C T T C C A T C C A A C C T T C C A T C C T T C C A T G G A A G C T A C C A T C G A T C G T A G C T T G C A A G C A A G G T T G C A A G C T A C C A A C C A T C C A A G G T T G G T A G G T T G G T A C C A T G G T A G G T A C C T A G C T T G G A A C C A A G C T T C C A A C C A T G G T A G G T T G C T A G C T T G C T T C C A T G C A A C C T A G G T T G G T A C G T A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C T T C G T A C G T A G G A A C G T T G G T T C G A A G C T T G C A T G C A A G C A T C G T A G C A A G G A A G C A A G C A T G G A T C G T A G C T A G C A A G C T A C C A A C C T A G C A T C G T A C C A T G G T A C G A A G G A T C C T T C C T A G C A A C C A T C G T A G C T T G G A A G C T T G G T T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T C G T A C C A A G C T T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G C T A G G A A G G T T G C A T C G T A G G A T C G T T G C T T G G A A G G T A C C T A C C A A G C A A G G T A G G T T G C T T C C A T C C A T G G A A C G A A G C A A C C A T C G A A C G A T C C A T C G A A G C A A G C A A G C A T G C A A G G T T G C A T C C T T C G A T C C A T C C A T G C A A G C T T C C T T G C T T C G A T G G T A C G T A C C A A G G T A C C A T C C A A G C T A G C T A C G T A C G A T C G A A G G A A G C A T G C A A C G T A G G T T C C T A G G T A G C A A G C T A C G A A G G A A G G T A C C A T G C A T C G A T C C T A C G A T G G A A G C T A G G T A G C A A G G A T G C T T C C T T C C T T C C A T G G T A C G A T G G T A C C A A G G T T C G T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C G T A G C T T C G T A G G T T G C T T G G T T G G T A C C A T G G T A G G A A C G T A C C T A C C T A G G T A G G A A C C T T C C T T G C T T C G T A C C A A G C T T G G T A G G T T C G T A C C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A G C A T G G T T G C A T G G T A G G A A G C A T G G A T C G T T C G T T G G T T C C T A G C A A C G T T G C A A G C T T C C T A G G A T G C A A C G T T C C A A G G T T G G T T G G A A C C T A C G T T C G T A G C T A C C A A G G A A G C T A C C A T C G T A G C T A C G A A C C T A G C A T C G A T C G A A G C A T C G T T G C T A G G A A G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C T T C C T A G C T A C C A A G C T T G C T A C C T T C C T A G C A T C C T T C C A T G G A A G C T A G C T A C C T A G C A A C G T T G C A A G G A A C C T A G C A +18 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A G G T T G C T T G C A A G G T T C G A A G C T T G G T A G C A T G C T T G C T A G C A T G G T A G C A T G C A T C G T A G G A T C G T A G C A A C G T A C G T A G G A A C C A T G C T T C G A T G C A A G C T T C C A A G C A T G G T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C G T A C C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T G C A A G C T A G G T A C G T T C C T A G C T T C C A T G C T A C G A T G C T T G G A T G G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T G C T A C G A A C G T A C G A T G C T T C G A A C C T A G G A A C G T T G G A A C G T A C G A T G C A A C C T A G G T T C G T A C G A A G G A T C C T T G C T T C G T T C G A T C G T A C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G A A G C T A C C A T C G T A C C A T G C A A C C T T C C A T G C T T G G T A G C T T G G A A G C T A G G A T C G T A C G T T G C A A C G T A G C A T C G A T C C T A G G A T G C T T C G A T G G T A C G T T G C T T C G T T G C T A G G T A G G T T G C T T C C T T C G T T G G A T G G A A G G A T G G A T G C A A C G T A G C T A G G T T C G A T G C T A G C A A G G T T C C T A C G A A G G T A G C T T C G A T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T G C A T C G T T G G T T G C A A G C A T G C T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G G T T C C A A G C T A G C A A C C A A C C T T C C T A G G T A G C A T G C T A C G A T G C T A C C T T G C A T C G A A G C T T C C T T G G A A C G A A G C T A C C T A C G T A G C A A G C T A G G A A G G A A C G T A C C A T G C A T G C A A C C T A C G A T G G T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C C T T C G T T C G A T G C T A C G A T C C T T C G A T C C T A G G A A C G A T G C T T G C A T G G A T C C A T G G T A G G T A C G A A C G T T G G A T G C A T G C A T G C A A C C A T G G A T C C T T G C A A C C T T G C T T G C A A G G A A G C T T C C A T C G A T C C T A G G A A G C T A G C A A G C T T G C T T G G T A C C A A C G T T C C T T G G A T G G T A C C A A G G A A G G A T C C A A G G T A C C T T C C T A G C A A C G T T C C T A G C T A G C T T C G A T G C A A G C T T C C A A G C T A G C T T C C T A G G T T G C T T G C T A G C T A G C A A G C A A C C T T G C A T G G T T G C T T C G A A C C T A G C A T C C A T C G A T G G T A G G A T G C A A C G A T G G T T C C T A C G A A G G T A G G T A G C T T G C T A G G A A G G T T C C T A G C A A G C T A G C T T G C A A C G A A G C A A G C T T G C T T C C A A G C T T C G A A G C T T G C T A C C T T C C T A G C A A G C A A C C T A G C A +19 A C G T A C G T A C G T T G C T A C G T A G C T A G G T A G G T A G G A A G G T T G G T T G C T T G G T T C G A T G C A T G G T A G C A T C C T T G C A A C C T T G C T A G C A T C G A T G G T T G G T T G G T A G C A T C G T A C C T A C G T A G C A T C G A T C G T T G C A A C C T T C G A T G G T T G G T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G C T A G C A T G G T T C C A A G C A A C C A A G C A A G G T T G C A A G C T A C C A A C G T T C C T T G C T T G C T A G G T T G G T A C C A T G G T T G C T A C G T A G C T T G G A A C C A A G C T T C C A A C C A T G G T A G G T T G C T A G C T T G C T T C C A T G C A A C C T A G G T T C G A T G C T T C G A A C C T A G G A A C G T T G G A A C G T A C G A T G C A A G C T A C C T T C G A A G G A A C G A A G G T T C G T T C G T T G C T T G C A T G G T T C C A T G G A A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G C A A C G T A G C A T C G A A G G T A G C T T C C A A G G T A G G A T G G A A G C T T G G A T G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T A G G A T G C A T C C T A G C A A C C A A G G T T C C T A G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T T C C T A G G T A C G T A G C A A G C T A C C T T G C T T G C A T C G T T G G T T G C A A C C A T G C T T G C A T G C A T G C T T C C A T C G A A C C A A C C T T C C T T G C T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G G T T C C T T G C T A C G A A C G T T C C T A C C A A G G T A C C A T G C T A C G A T G C T A C C T T G C A T C G A A G C T T C C T T G G A A C G A A G C T A C C T A C G T A G C A A G C T A G G A A G G A A C G T A C G T T G C T T C G A A C C T T C G A A C G A A G C T A G G A T C C T T C C T T G C A A C C T A G C A T C C A T G G T A C G T T G G T A C C T A G G T A C C T A C G A T G G A T C G T A G G A T G C T T G G A T C C T T C G T T G C T A C G T A G G T A G C T A G C T T G G A T G C A T G G T T G C T A G G A A C G T T G G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C G T T G C T T G G A T G G A A G G T A G C A T C C A T C G A T G C A A G C T A G C A A G C T T C C T T G G A A C C A T C G T T C C T T G G A T G G A A G G A A G C A A G C T T G G T A G G A T G G T T C C T T C C T A C G T A G C A T G C T T G C T T G G A T G G A A G C A A G G T A C G A A G C T T C C A T C C A A G G T A G C A A G C T T G C A A G G A A G G A A C C T T C G T A G C T A C G T A C G T A G C A T C C A T C C A T G G T A G C A T G C T A C C A T G G T A G C T A C G A A G G A T G C T A C C A T G C T T G G A A G C T T C C T A G G T A C C A A G C T T G C T A C C T T C C T A G G T T G C T T C C T T G G A A C G A A G C T A G G A A G C A A C G T T G C A A G G A A C C T A G C A +20 A C C T T G G T T C C T A G C T A C C T T C C A A G G A A C G T A C G A A G G A T G C T T G C T A G G A A C G A A G C T A G G T A G C A T C C T T G C T T G C T T G C T A G C A T G C T T G G A A C G T T G C T A C C A T G C T A G G T A G C T A G C A T C C T T C G T T G C A A G C T T C G T A G G T T G C T T C C A T C C A A G C A A G G A A C C T T C C A T G G A A G C T A C G A A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T C C A A G G T T G G T A G C T T C G T A C C T T C C A T G C T A G G T A G C T T C C A A C C A A G G T A C C A A C G A T G C T A C G A A G C T T C C T T G C A A C C A T C C T A C C A A G G T A C G A A G G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C G T A G C T T C G T A C G T A G G A T C C T T G C T T C G T T C G A T C G T A C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C A A G C T A C C A A C C T A G C A T C G T A C C A T G C A A C C T T C C A T G C T T C C T A G C A A C C A T C G T A G C T T G G T A C C T A G G A A G G T T G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G C T A G G T T C G A T G C T A G C A T C G T T G C T A C G A A G G T A G C T T C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G G A T G C T T C C A T C C T A C G T T G G T A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G G A A C C T A G C T T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A T C C T T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C A T G G T A C G T A G G T A G C A A G G T T C C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C C T A C C A T G C T T G C T T C C T T G C A T C G A A C G A T C C T A G G T T G C A T G G T T G C T A C C A T C C T T C G A A G G A A G G T A G C T A C C T T C C A T G G A A C C A T G C A A G G T A G C A T G G T A G C A A C C A T G C A T G G A A G G A T G G A T C C T T C C T A C C A T G C T A C C T A G C T T G G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T A G C T A G C T A G C A T G C A A G G A A G C T T C C A T C G T T G C T A C G A A C C T A G C A T C G A T C G A A G C A T C G T T G C A A G G A T G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C A T C C T T C C A A G C A A C G T A G G T A C C T A G C A A C C T A G C T A G C A A G C T A C G T +21 A C G T A G G T A C G T T G C T A G C T T C G A A G G T T G G T A G G A A G G T T C C T T G C T T G G A A C G A T C C T A G G T A G C A A C C T T C C T A C C T T G G A T C C A T C C A T G G A A C C T A G C T A C C A T G C T A C C A A C G A A G C T T G G A T C G T T G C A A C C T A C G A A G G T T G C T T G C A T C C T A G C T T C C A T G C A T C C T T G G T T G C T A G C T A G C T T G G T A G C T T G C A A G C A A G G T A G C T A G C T A C C A A G C T A C C T T G C T T G C T A C C T T C G T A C G T T G G A A G G T A C C A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A C C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T T G G T T G C T A G C A A C C A A G G T A C C A A G C A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C A A C G A A C C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A C C T T G G T T G C A T G G A T C C T A G C T A G G T A C G T T G C A A G C T A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A A C C T A G C A A G C T T G C A A G C A A G C T T G C T A C G A A G G A A G G T T C G A A G G T A C C T T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C A T G G A T C G A T G G T A G G T A G G T A G C A A C C T A C G A A G G A T C G T A C C A T G C T T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T C C T T G G A A C C A T G C A A G C A T G C A T G G T A G G A A G G A T G G T T C G A A G G A T C C T T C C T T G C A A C G T T G C T A G C T A G G T T G G A T G C T T G C T A C C T A G C T A G G T T C G T A C G T A G C T T G G T A G C T A C G A A G G A A C G A T C G T T C G T T G C T A C C A A C C T A G C A T C G A T C G A A G C A T C G A T G C T A G C A T G G A A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +22 A C C T A G G T A C G T T G C T A G C T T C C T A G C T A C C T A C C A T G G T T C C T T G C A A G G T T C G A T C C A A C C A T G C T A C C T T C G T A C C T A G C T A G C A T G C T T G G T A G G T T G G A A G C A T G G T A C C A A C G A T G G A T C C T T C C A T G G A A C C A A C C A T G G T T G C T T G C A T C C T A G C T T C C A T G C A T C C T T G G T T G G A T G G A T C G T T C G T A C C T T G C A A G C A A G G A T G C A A G C T A G C A A C C T A C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G C T A C C A A C G A A G G T A G G T T G C A A C C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T C C A A C C T T G C T T C G T T C G A A G C A A G G T T G G T T C G A A G C T A G C A T G G T A G C T T C G A A C C A T G G A A C C A A G C A T G G T A G C A A G C T A G C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G G A A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C C A T G C A A G G A A G C A T C G A A G C A A G C T T G G T A G C T T C G A A C G A T C G T A C C A T C G A A G C A T G G A A G G T A C C T T C C T A C G A A C C T T C C T A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C T A C G A A G C T A G G T A C C A A C C T T C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A A G G T A C C A T G G T A C C T T G G T A C G A A C G T A G C T A G C T A G C T A C C T A G C T T C G T A C C A A G C T A C G T T G C A A G G T T G C T A G C A T C C A T G C T A G C T T G G A A C C A T G C A A C G T A G C A A C G A T G C A A G C A A G G A T G G T A G G A T G C A A G G T T G G A T C G T A C G T T C C T T G C T A C G T A G C T A G C A A G G T T G G T T G C A T G C T A C C T A G C T A G G T T C C T T G G T T G C T T C G T A G C T A C C A A C C A A G C T A C C A T C G T T G C T A C G A T C G T A C G T T C C A T C G A A G C A T C G T T G C T A G G A T G G A T C G A A C G A T G C T T C C A A C G A T G C T T G G A A G C A A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +23 T G C A A C G T A C C T A G G A T G G A A C G A A G C T A C G A T C C A A G G T T G C T T G C T T G G T T C G A T G C T A G G T A G C A T G C T T C C T A G C T T G G T A G C A T G C T T G G T A G C T T C G T A C C A T G C T A G C A A G G T A G G A T G C T T C G A T G C A A C C T T C G A A G C T T G C T A C C A T C C A A C C T T C C A T C C T T C C A T G G A A G C T A C C A A G C T T C G T A G G T A G C T A G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G C T T G C T A C C T T C C A T G C T A G G A T G C T T G G A T G G T A G C T A C C A A C G A T G G T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T C C T A G C T T C G A A C C T A G G A A C G T A G G T A C G A A C G A T C C A A C G T T G C T T C G T A C G T A G G A A C G T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A G C A A G G T A C C T T G C A A C C T A G G T A G C A A G C T T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T G G T A C C A A G G T A G C A A G C T T C C A A G C A A G G T A G G T A G G T A G C A A G G T T G C T T G G A A G G T A G C A A C G T A G C A T G G A T C C T A C G T A G G T T C C A T G C A A G C T A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G G A A C C T A C C A A G G T T C G A A G C T A C C T T C G T A G G A A G C A T C G A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C A T C C T A C C A T G C T A G G T A G C A A G G A A G C A T C C A T G G A T C G A A G C T T C C T A C G T A G C A T C C T A C G A A C G A A G C T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A T G G A T C C T T C C A T G C T T C G T T G G T T G C T T G G T A C G T A C C A A C C A T G C T T C G A A C C T T C C T A G G T A G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A A G G A A G G T T G C A T C C T T C G T A G C A A C C T A G C A A G C T T C C T T G C A A C C A T G C A A G G T T G G A T G G T A G G A T C C T T G G T T G G T A G G A T G C T T C C T T C G T A G G T A G G T A G C A T C G T T G C T A G C A T G C T A C C T A G C T A G G T T C G T A C G T A G C T T G G T A G C T A C C A A G G A A C C T A C C T T C G T A G C T A C C T A C C A A C C A T C G A T C G A T C C A T C G A T C G T A G G A T G G T T C G A A C G A A G G T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +24 A G G A A C G T A C C T T C C T A C C T T C G A A G G T A C G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A C C T A C C T T C C T A C C T A G C T A G C A A C C T T G G T T G G T T G G T A G C A T C G T A C C A A G G A A C C A T G C T T C G A T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T C C A A C C T T C C T T G G T A G C A A G C T A G G A T C G T A G C T T G C A A G C A A G G A T G C T A C C T A C C A A C G A T C C A A G C T A G G T A G G T T G G T A G G T A G G T A G G T A G C A T G C T A C G A A C G A A G G T T C C A A C G A A G G T T G G A T G C A T G G T T G C A A C C A T G C A A C C A A G G T A G G T A C G T A C C T A G G T A C C T A C G A T G G T A G G T A C G A T G C A T C G T T G G A A G G A A G G T A G C A A G G T T G G A T C G T T G C T T G C A T G G T T G C T T C C T A G C A T C G A A C G T T C C A T G C A T C G A A C C T A C C T A G G A A G G A A C G A T G C A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C T T G G A A G G T A C C T A C C A A C G T A G G T A G C T T G C T T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G T T C G T T G C A A C G T T G G A T C C T A C C A T C C T T C G T A C C A A G C T T C G A A C C A A C G A A G G A A G C A A G G T T C C T T G C A T C G T T C C T A C G A A G G T A G C T T G G T T G G A T G G A T G C T A G C T A G G T A C G T T G C T T G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C T A C G A T G C A A G G A A G C A T G C A A C C T A C C T A G C T T G G T T C G A T C G A A C C T A C G T A G C T T G G A T G G T A G C A T C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G A A G C T A G G T A C C A T G C T T C G A T C C T A G G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T A G C A T C C A T G G T A C G T A G G T A C C A A G C T A C G T A G G A T G G T A C G T A G G A T C G T T C G A A C C T T C C T A G C T A G G A A C G A T G C T A G C A A C G A T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C A A G C T T C C T T G C A T G C A T C C A A C C A A C G T T G C A T C G T A C C T T C C A T C C T T C G T A G G A A G C T A G C A A G G T T G G T A G C A T C C A A G C A A G G T T G G A T G C T T G C A A C C A T C G A T C G T A C G A T G G T A C C T T C C T A G C A T C C T A G C T T G G T T C G T T G G A A C G T A C G A T G C T A G G T T C G T A C C T A G C T T G G T A G C T A G G A A G C A A G C T T C C T T C G T T G C A A C G A A C G T A C G A T C C A T C G A T C C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C C T T C C T A G C T T G C T T C G T A G C A T C G T A G C T A G C T A G C A A G C A A G C T A G C A A C C T A G C T +25 A G C T A C G T A C C T T G C T A C C T T C G A A C C T A G C T T C C T A G G A T G C T T G C A A C C T T C C T T G C T A G G T A G C T A C C T T C C T A C C T T G G A T C C A T G C T T C G T A G G A T C G T A G C A A C G T A C C T A G G A A C C A T G C T T C G T T G C T A G C T T G C A A G C T T G G T T G C A T C C T A G C A T C C A T C C T T G C T T G G A A G C T A C C T A G C T T G G T A G C T T G C A A G C A A G G T T G C A A G C T A G C A A C G T A C C T A G C T A G C A A G G T T G G T A G C T T G G A T G C T T C G T A G C T A C G A A C G T A G G T A C C A A C G A T G G T A G G A T G G T T G C T T G C A A C C A T G C T A C G A A C G T T G G T A G C A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G T A G G A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C G A A G G T A C G A T G G A A G C T T G G T T G G T A G G T A G G A A G G T A C C A A G G T A C G A T G G T A C C T T G C T A C G T A G C A A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G G T T C C A A C C A A C C A A G C A A G G T A G C T A G G A T G C A T C G T T C G A A C G A A G G T A G C T T G G T T G G A T G G A T G C T A G G T A G G T T G C T T G C A A G C T A C C T T G C T A C C A T C C T T G G T T G G T T G G T T G C T A C G A T G G A A G G T T C C A T C C A A G G A A C C T A C C A A G C T T C G A T C G A A C C T T C G T A G G A A G C A T C G A A G C A A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T T G C T T C G T T G G T T G C T T G G T A C G T A C C A A C C A T G C T T C G A A C C T T C G A T G C T A G C A T G C T T C C A T G C A A G C A T G C A A C C T T G C T T G C T A G G A A G G T T C C T T C G T A G C A A G C A A C C T T C C A A G C T T C C A T G C A A C C A T G C A A G G T T G C A T G G T A G G A T C C T T G G T T G G T A C G A A C C A T C C T T C C T A G C A T G G A A G C T T G C A A G C A T G G A A G C T A C G A A G C T A G C T T C C T A G G T A C C A T G G T A G C T T G C A A G G A T C G A A C C T T C G T A C C T A G C A A C G T A C G A T C C A T C G A T C C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +26 A G C A A C G T A C C T T C C T A C G T A G G A T G G A A G C A A C C A A G G A T G C T T G C T T G G A A C G A A C C T A G G T A G C T A C C T T C C A A C C T T G G T A G C A A G C A T C G T A G C T T G G T T C C T T G C T A C C A A C G A A C C A T C G T T C G T T G C A A G C T T C G T A G G T T G C T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C T A G C T T C C A A C C A A G C A A G C T A G G T A G C T A C C T A C C A A C G T T C C T T G C A A C G A A G G T T C C T A G C T T C C A T G G T A C G T A G C T T G G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T C C T A C G A A C G T A G G A A G C T T C G T A C G T A C G A A C G T A G G A A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A A C C T T G G T A C G T T C G A T C G T A C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G C T T C C A T G C A A C G T T C C A T C C T T G G T A G C T T G G A A G G T A G G A A C G A A G C T A G G A A C G T A G G A T G G T A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T T G G A A G G A T G C A A G C T T C C T A G G A A G C A A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T A G C T A G G T A C G T T G C T T G C A T G C A T C C T A C G T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G G T A G G T A C C A A G C A A G C T A C G T T C G A A G C T A C G T T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T A C G T A G G A T G G T A C G T A G G A T C G T T C G A A C C T T C G T T G C T A C G T A G C T T G C T T G G A A G C A T G C A T G G T A G G A T G G A A C G A A C C T A G G T A G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G A A G G T T G C A T C C T T C G T A G G A A G C T A G C A A G C T T C C T T G C A T C G T T G C A A G G T T G G A T G G T A G G A T G C T T G G A T G C A T C G A T G G T A G G A T G C A A C G T T C C T A G C T T G G T T C G T T G G A T G C T T C C T A G C T A G G T T C G T A C C T A G C T A G G T A G C T A G G A A G C A A C C T A C C T T C G T T G C T A C G T A C G T A C G A T C C A T C G A A G C T A G G A T G C T A C G T T G G T T C C T A C G A T C C A A G G A A G C T T G C T T C C A T C C T T C C T T C C A A G G T A G G T T G C A A C G A A C C T A G C T T G C T T C C A A G G A A C G T A G C T T G C A A G C A T C G T T G C A A G C A A C C T A G C A +27 T C C T A G G A T G G T T C C T A C C T A G C A A G G A A G C A A C G A A G G T T G C T T G C T T G G T T C G A T G C T A G G T A G C A T C C A A G G T A C C T T G G T A G C A T G C A T G G A T C C T T G C T A C C A T C G T A C C T A G G A A G C T T G C A A C G T T G C A A G C T A C C T A G C T T C C T A C C A T C C T T G G A A G G A T C C A T C C A T G G A A G G A A C G A A G C T T G G T A G C T T G C A A G C A A G G T T G C T A G C T A G C T A C G T T C C A A G G T A G C T A G G T T G G T A G C T T G G A A G G T A G G A A G C T T C C A A C G T A G C T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C C A T C C T A C G A A C G T A G G T A G G A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A C C T A C C T T C C A A G G A A G C A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G C A A G G A T G G T A G C A A G C T A G C T A G G T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T A G G T A G C A T C C A A G G T A C G A T G G A A G C T A G G A A G C T A G C A A C C T A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A A G C T T G G T A C C A A G G A T C C T A G C T A G G T A C G T A G G A A G G A A G C T T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C C T A G C A A G C A T C C T A G C A A C C A A G G T T C G A T C C T A C G T T C G A A G G T A C C T T C C T A G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A C G T A C C A A C G T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A T G G A T G G T A C C T A G G T A C G T A G G A T G G A T C G T A G G A T C G T T G G A A C C T T C C T A C C T A G C T A G G A T G C T A C C T A C G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C A T G C A A C C A T G G A T C C T T G C A A C C T T G C T T G C A A C G A A C G T A C C A T C C T T C G A A C G A A G G T A G C T A G C T T G C T A G C T A C C A T G C A T G G T T G C A A G G T A G C A A G G A T G C T T C G T A G G A A C G T A C C T T C C A A G C A T C C T A C C T A G G T T C C T T G G A A G C T A C C T A G C T A G G T T C G T T C C T T G G T T G C T A G C T A G C A A G C A A C C T A C C A T C G T A C C T A C C A A C C T A C G A T G C A T C C A A G C A T C G T T G C T A G G A T G G A T C G T A C G A T G C T T G C T A C C A T G C T A G G A A G G T A C C T A G C T A C G T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A G C A A C G A A G C T A C C A A G G T A C C T +28 T G G T T G G A T G C T T C C T A C C T T C C A A G G A A C G T A C C A A G G A T G C T T G C T A G G T T C G A T G C T A G G T A G C A T G C T T G C T A C C T T G C T A G C A A C C A T G G A T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T G C A T C C A T G G A T G C T T C C A T C G A A C C T A G G T A G C T A G C A A G C T T G C T A C C T A C G A A C G T T C C T T G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A A G C T A C G A A C C A A G G T A C C A A C G A A G G T A G G A T G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T A C G A A C G T A G G A A C G A A C G T T C C A A C G T A G G T T C G A A G G A T C C A T C G A T G C T T C C T T C G T T G C A T G G T T G C A T G G A A C C A T G G A A G C A A G G A A C C A T C G A A C C A T C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T T G C T T C C T A C C T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A C G T A G G A T G G A T C C A A G G A A G C T T C G A T G G T A C G T T G C T T C G T T G C A A C G T A G G T T G G A A G C A T C C T T C G T A C C A A G C T A G G A T G C T T C C A A C G T A G G T T G C T A C C T A G C A T G G T T G G A A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G C T A C C T A G G A A G G A A C C T A G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T C C A A C G A A C C A T G G A A G C A T C G A A G C A A C C T T G C T T C G A T C C T A C C T T C C A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T G C T T G G A A C G A T C G A T C C T T C G T A C C A A G C T A G G A A G G A A G C T A C C A T G C A T C G A T C C T A C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T T C G T A C G A T G G A T G G T A G G A T G C T A G G A T C C T T C G T T G C T T C G T A G G T T G C T T G G T T G G T A C C T A G G T A G G A A G C T A C G T T G C T A G C T A G C A A C C T T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C G A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T G G T T C G T T C G T A C G T T C C T T G C A A C G T T G G A A C C T A G C A T C C T T G G T A G C T A C G T T G C T T C G A A C C T A G G T T G C T A G G T A G C T A G C A A G G A T C G A T C G T T G C A A G C T A C C T A C G T A C G A T C C A T C C A T G C T T G G A T C G A A G G A T G G A T C C T A C G A T G C T A C C A A C G A T G C T T C C A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G G A A G G T T G G T T C C A A G C T A C C T A G C T A G G A A C G T T C C T A G C A T G C A A G C T A C G T +29 T G C T A C G T A C G T T G C T A C C T T G G T A G G T T G G T A C C A A G G A T G C T T G C T A C G A A G G A T G G T T G G T T G C A T C C T T C C T A G C T A G C T A G C A T C G T T G G A T C C T T G C T A C C A T C C T A C C A A C G T A C C A A G C T T C G T T G C A A G C T T C G T T G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G G A A G C T T G C A T C G T T C G T A G C A A G G A T C C A A G G A A C C T A G C T A C C A A G G T T C C T A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A C C T T G C A A G G T T C G A A G C A A C G T T C G T A C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C A T C C T T G G T A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C C T T G G T A C C A A G C A T G G A T G G A T C C T A G G A A G G T A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G G A T C G A T C C T A G G A A G G T A C C T T C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T C G A A C C T T C G T A G G A A G C A T C G T A G C A A C C A A G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G C T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T G G A A C G T T G G A T G C A A G C T T C C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G C T T G G T A G G A A C C A T G C A A G C T A G C A A G G A A G G A A C C T A G C T T C G T A G G A A C G T T G C T T C C A A G C A T G C T A G C A A G C A T C C T T G G T A G C T T C C T A G C T A G G T T C G T A G C T A G G T T C G T A G C T A G G A A G G A A C C T A C C T T C G T T G C T A C C A A C G T A C G T T C C A T C G A A G G T A G C T T C C A A G C A T G C T T C C T T C G T A G C A T G C T A G C A T G C T T G G A A G C A A C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C A T G C A A G C A T C C T A G C A T G C A A C C A A C G T +30 A G C T T G G A T G C T T C C T A C C T A G C T A G G A A G C T A C C A A G G T T G C T T G C T A G G T T C G A T G C T T G G T A C C T A C C T A G C T A G C A T G G T A C C A T C G T A G G T T C C T T G G T T C C A T C C A T C G T A G G A A C C A T G C T T C G A T G C T A G G T T C C T A C C T T G C T A C C A T C C A A G C A A G G A A C C A T C C T T G G A A G C T A C C A T C G A T C G T A G C A A C C A A G C A A G G T A C C T A G C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A G G A A G C T T G C A A C C A T C C A A G G A A C G A A C G T A C G T T C G A A C G A T G G A A C G T A G G A T C G T A C G A T G C A A G C A A C C A T C C A A G G A T C C A T C G T T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A T C G A A G G A T G G A A G G A T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G T T G C T A G C T A C C T T G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T C G T T C C A A C G A A C G A A C C T A G C T A C C T A G G A T G C T T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T A G C T A G G T T G C T T G C T T G C A A C C T A G C A A C C A A C C T T C C A T G C A A C C A T C G A A G C A T C G A A C C T T G C A T C C A A C C A A C C T T C C T T G G T T C C A T C C T A G G T T C G A T C G A T C C A A G C A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A G C A T C C T A C G T T C G A A G C T A C C A T G C A T C G A T C C T A C G A T G C T T G C A T C G A A C C A A G G A A C G T A G C T A G C A T C C A T G G T A G C T T C C T A G C A A C C T A C C T T G G A T G G A T C G T A G C A T G C T T C G A A C C T T C G T A C C T T G G A A G G A A G C T A C G T A C G T T G C A A G G T A G C T A G G T A C G T T G G A T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A G G A A G G A A G C A A G G T T C C T T G G A A C C A A G C A A G G T T G G A T G G T A G G A T C G A A C C T T G G T A G C A A C C T T C G T T C C T A C G T T G G T A C C T A G C T T G G A T G C T T G C T A C C T A G C T A G G T T C G T A C C T T C G A T G C A A G C T T G C A A G G A A G C T A C C T T C G T A G C T A C C T A C C T A G C A T C G A T C G A A G C T T G G A T G C T A C C A T G C T A G C T A G G T A G G A T C C T A G C A T C G T T G G T A C C A T C C T T G C T A G G A A C C T T G C T T C C T T C C T A G G T T G G T T G C T A G C T A C G A T G C T A G G A T G C A T G C T T G G T A G G A A G C T A C G T +31 T G G T T G G A T G C T T C C T A C C T T C C A A G G A A C C A A C G A A G G T T G C T T G C T A G G T T C G A T G C T A G G T A G C A T C C T T G C T A C C T T G C T A G C A A C C A T G G A A C C T T G C A A G C A T C C T A C G T A G G A A G C T T G C A T C G T T G C T A G C T T C G A A G C T T G G T T G C A T C C T A G C A T C C A T C C T T C C A T G G A T G C T A G C T A G G T T G G T A G G A T G C T A C G A A G G T T G C T A G C T A G C T A C C T T G C A A G G T A G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T C C A A C C A A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C C T A C G T A C G A A G C A A G G T A C G T A C G A T G C T A G C T A C G T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T T G C A T G G A A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T A G G T A G C A T C C A A G G T A C G A T G G A A G C T T G G A A G C T A G C A A C C T T G G T A G C A A G G A T G C A A G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T A C C T T C G T T G C A T C C A A G C T A C G T T G G A T C C A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T C G A A G C T T G G A T C C T A G C T A G C A A C G T A G G A A G G A A G C T T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T A C G A A C C A T C C A T G C T T G C A A G G T A C C T T G C T A C G A A C C T T C G T A C C A A G G T A C C A A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A C G T A C C A A G C T A G G A A G C T A G C T A C C A A G C A T C G A T C C T A C G T A G G T T G C T A C G A A C C A A G G A A C G T A G C T T C G A A C C A T C C T T C G T T G G A T G C A A G C T A C G T A G C A T G G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T A G C T A G G A T G C T A C C T T G G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C A T G C A A C C A T G C A T C C T T G C A A C C T T G C T T G C A A G G T A C G T T C C A T C C A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C A T G C T T C G T T G G A A C G T A G C T T C C A A G C A T G C T A C C T A G G T T G G A T G C A A G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A A C C T A C C A A C G T A C G A T G C A T C C A A G C A T C G T T G C A A G G A T G G A T C C T A C G A A G C T A C C A A C C A T G C T T C C A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A G C A T C G A A G C T A C C A A G G T A C C T +32 A C C T A G G T A C G T T G C T A G C T A G C T A G G T A G C A A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C T T G C A T G G T A G C T T C C A T G G A T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G C T T C C A T C G A A C C T A G G T A G C T A G C A A G C T T G C T A C C T A C G A A C G T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G C T T C C T T G C A T C C A T G C T A C C A A C G T T G G T A C G T A C C T A C G T A C C A A C G T A G G A A C G A A C G A T G C T A C G T A G G T T C G A A G G A T C C A T C G A T G C T T C C T T C G T T G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T A G C A A G C T A G C T A G G T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A A G C T T G G T A C C A A G G A T C C T A C C T A G C T A C C T A G G A A G G A A C C T A G C T A C C A T C C T A C G T T G G T A G G A T G G A A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C C A A G C A A G C A T C C A A G C A A C C T T G C T T C G A T C G T A C G T T C C A A G G T A C C T T C C T A C C A T C C T A C C T A G C A T C G A A G C T A G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A C C A T G C T T C G A T G C T T C G A A C G A T C C T A G C A A C C T A G G A T C G T T G C T T G C A T C C T A G G A A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A T C C T T C G T T G C T A C G T A G G T T G C A T G G T T G G T T G C T T C C T T G C T A G G A A C G T T C C T A C C T T G C A T G G A A C C T T G G A T C G A A C G A T C C T A G G T A C C T A C G T A C G T A C C A T C C A T C G A A C G A A G G A A C G A A G C A A C C T T G G A A C C A T C G T T C C T T G C T T G G A A G G A T C C T A C C T T G G T A G C T A C G T T C C T T C C A A G C A T C C T A G C T A G C A T C C T T G G A A G C T T C C T A G C T A G G T T C G T T C C T T G C T T G C T A G C T A G C A A G C A T C G A T C G T T G C T T C C T A C C T A C G A A C C T T C C A T C C A T G C A T C G A T C G A A G G A T G G A T C C A A C G A T G C T T G C T A C G A T G C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C T A G C T T G C T T C C T T G C A T C G T A G G T A C C T A G C T T C G A A G C T A C C A A G G T A C C T +33 A C G A A C G T A C C T T G C A T G C T T G C T A G G T A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T A C C T T G G T A C C T A G G T A G C A A C C A T G G T T C G T T G G T A G C A T C G A T C C A A G G A T G G A T G C A A C C T T G C A A G C T T C G T A G G T T G C T T G C A T C C T A G C A T C C A A C C T T C C T T G C A T C C T A C C A A G C T T C G T T G G T A G G A A G C A A G G T A C C T A G C T A C G A T G C A T C C A T G C T T G C T A C C T T G G T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C C A A C C T A C G A T G C A A G C T A G G A A C G A A C G A T G C A T C G T A G G A A C G T A C G T A G G A A C G T T C G A A C G T A C C T T G C A T G G T T G C A T G G A A C C A T G G A A G C A A G G A T G G T A G C A A G C T A G C T A G G T A G G A T G C A A G C T T G G T A C C A A C C A A C G T T C C A T G C A A G C T A C C A A C G T A G G T A C C T T G G A A G C T A G G A A G C T A G C T A G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A A G G A A C C A A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C A A C G T A G C A T G G A T C C T A C C T A G C T T G C T A G G A A G C T A G G T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C G T T C C A T C C A T G G A T G C T A G C A A G G T T C G A T C C T A C G A A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A A G G A A G C T T C C T T G C A T G G T A G G T T C C T A G G T T G C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G T T G C A A G G A T C C T A G C T T G C A T C C A T G G A A C G T A G G T A C C A A G G T T C C T A C G A T C C T A C G T A G C A T G G A T G G A A G C T T C G T A C C T A G G A A G G A A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T G G A T G C T A G C T T G G T T C C A T G C A T C C T A C G A A C C T A C G T A G C T T G G T T G G T A C C A T C C A T C G A T G G A A G C T A G C A A C C T T G G T A G C A A C C A T G C A T C C T T G C A T G G T A G G A A G G A A C G A T G G A A G G T A C C T T C C T T C C T A G G T A C C T A C C T A G G T T G C A A G C T T G G T T C C T T G C T T C G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A C C T T C C A T C G A A G C T A C C T A C C A A C C A T G C A T C G A T C C T A G G T T C G A A C G T T G G A T C C T A C G T A G G A T G C T T C C A T G G A T G G A A C C A T G C T T C C A A C C A A G C T T G C T T C G T T G G T A G C T T G C T T G C A A G C A A C C T A G C T T C C T A G G T A C G T A G G T A G G T A G C A A C G T +34 A G C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T A C G A A G G T T G G T A G C A T G G A A C G A A C C T T G G T A G C T T C C A T C C T A G C T T G G T T G C A T G G A A C G A A C C T T G C T A G C A T G C T A C C A A C G A T G C A A G C T A C C A T G C A A G C T T G C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A A G C T A C C A T C G A T C G T A G C A T G C A A G C A A C G T T G C A A G C T A G G A A C C T T G C A A G C T A G G T A C C T T G G T A G C A T C C A T G C T A C G T A G C T T G G A A C G A A G G T T C C A A C G A T G C T A G G A A G G T T G C T T G C A A C C A T G C A A C C A A C G T T G G T A G C A A C G T A G G A T G C A A G C A A G G T A C G T A C C A T G C T A C C A A C C T T C C A A G G A T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T A C G A A G C A T G C A A G C T A G C T T C C A A G G T A G C T T G G A A C C T A G G A T G C T T C C A A G G A A G G A T G G A A G G T A C G A T G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T C C A A C C A A G G A A G G T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G G T A C C T A G G A T G G T A C C A T G G T A G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T G C T T C C A A C C A A C C T T C C T T G C T T C G A T C G A A C C T T C G T A C G A A G C T T C G T A G C A A C C A T G C T A C G A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C T A C C T T G C A T G C A A G C T A C C T T G C A A C G A A G G T A C C A A C G T A G C A A G C T A C G A A G C T A G G A A C C T T G C T T C G A T C C T A C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G T A G G T A G C A A C C A A G C T T G G A T C G T T C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G C T A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C C T A C G T A C C A T C C T T C G A A C G A A G C T A G C T A C C T T G G T A G G A A C C A T C G T T C G T T G C A A G G A A G G A A G G A T G C T T G G T A G G A T G G T T C C T T C C T A C G T T G G T A C C T A G C A T C C T T G G T A G C T A C C T A G C T A G G T T C G T T C C T T G C A T G C A A G C T T G G A A C G T A C C T T C C T T C G T T G C A A C G T T C C T A C C A T G G A A G G A A G C T A G G A T G C A A C G A T G G A T C G A A C G A T G C T T G C T A C G A T G C T T G G A A G C A T C C T T G G A A C G A A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C A A G C A T G C T A G C A T G C A A G C T A C G T +35 A C G T A G G T A C G T T G C T A G C T T C G A A G G T A C G T A C G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C T T G C A A C C T T G C T A G C A A G C A T G G A A G G T T G C T A C C A T G C T A G C A A G C A A G G A T G G A A C G T T G C A A C C T T C G A T G C T T G G T T G C A T C C A A G C T T C C A T G C A T C G A T G G T A G C T A G C A T C G T T C G T A G C T A G G A T G C A A G G A T G C T A G C T A G G A A C G A T C C A A G G T A G C A A C G T T G G T A G G T T G G T A G G T A C C A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C A T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T T G G T A C C T A G C A T G C T T C G T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T T G G T T G C T T C C T T C G T T G G T A G G A A G C A T G C A A G C T T C C T A G G A A G G T A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T C C T T G G A T C C T A G G T A C C T A C C T A G G A A G G A A C C T T G C A T G C A T C C A T C C A T G G T A C C A T G G T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G G T A C C A A C G T A C G A T C G T T C C T A C C A A G C T A C G T T C C T A C G A T G C T A C G T A C G A T C G T A G C T T C G A T G C A A C G A T G G T T G C T A G G T A G C A A G C T A C G A A G C T A C G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T C C T A C C A T G C T T C C A T G G A A G G T A G G T T G C A A G G T A C C T A C G A T G G A T C G T A G G A T G C A A G G A T C C T T C G T A C C T A G G A A G G T T G G T A C G T A G G A T G C A T C C T T G C T T G G T A C G T T G G A T G C T A G C A T G C T T C C A T G C A T C C T A C C A A C C T T G C T A G C A A G G T A C G T T C C A T C C T T C G A T G G A A G G A A C C A T G C T T G G T T G G T A C C A T G C A A G G T A G C A T G G T A G G A T C G A A C C T T G G T A G C A A C C A T C C T T G C A T G C A T G C A A G C T T G C T T G C T A G G A A G C T A C C T A G C T A G G T T C G T A C C T T G C T T C G T A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C T A C C A T G G A A G G A A G C T A G G A T G C A A C G T T G G A T C C T A C C A A G G A A G G T T C C A T C G T T G G A A G C A A C C T T G C T T C C T A C G T T G C T T C C T T C C A A G C T T G C T T C C T A G G A A C G T A C G T T G C T A G C A A G C A A G C T A G G A A G C T A G C T +36 A C C T A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C G T A G G T T G C T T C C T T G G T T C G A T G C A A G G T A G C A A G G A T G C T A C C T T G C T A G C A T C C T T G G T T G G T T G G T A G C A T C C T A G G T A G G A T G G A T C C T T C G A T G C T A G C A T C C A A G C T T G G T T C C A T C C A A G C A T C C A A C G T T C C A T G G T A G G A T G G A T C G A T C G T A G C A A G C A A C G A T C G A A G C T A G C T A C C A A G C T A C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T C G A T G G T A G G A A G G T T G C T T G C A A C C A T G C A A C C A A C G T A C G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A G G A A G G T A G G A A G C A A G C A A C C T A G G T A C C A A G C T T C C A T C C A A G C T T G C T T C G T T G C A A G G T T G G T T G G T T C C T T C G T T G C T A C C A A G G A T G C A A G C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T T G G A A C G T A G C A T C G A T G G T T G G A T C C T A G C T A G G T A G C T T G C A A G C T A C C T T G C A T G C A T C G T T C C A T G G T A G C A A G G A A C C T A C G A A G C T A G C T T C C A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C C T T C C A T C C A T G G A T G C T A G C A A G G T T C G A T G G T A C G T T C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T T C C A T G C A A C G A A G C T T C C T A C G A A C C A T G C T T C G A A C C T A G C T A C G A A G C T T G C A A C C T A C G T A C G T T G C T A C G A A C C T A G G A T G C T T G C T T C C T T C C A T G G T T C C T A G G T A C G A A C C T T C C T A C G A T G C T T C G T A G G A T C G T A C G A T C G A T G G A T C C T A G G A A G G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T T C G A T C C T T C G T T C C A A G G A A C G T A G C A A C C T T G C A A C C A T G C A A G C A A G G A A G G A A G G A A C C T A G C T T C G T A G G A A G G T T G C T T G C A T C G T T G G A A C C A T G C A T G G A T G C A A G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C G A A G C A T C G T T G C T A G G A T G G A A C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C A A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +37 A G G A A G G A T G C T T C C T A C C T T C G A A G G T A G G T A G C A A G G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A T C C A A C C T A C C T A G G T A G C A T G C T T G G A T C G T T G C A A G C A T G G T A G G T A G G A A C C A T G C T T C G T T G C A A C C T T C G A T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C G A A G G T T C C A T G G A A G G T T G G A T G C T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T T G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C C T A C G T T C G A A G C T A C C T T G C T A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A A G C T T G G T T G G A T G C A T G G T T G C T A G G T A C G T T C C T A G C T A G C T T C G A A C C A A G C A T C C T A C C A A C C T T G C T T G C A A G G A T G C T A C G A T C C T T C G A T G G A A G C T A G C T A G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G T A C G A T G C A A C G T T G G T A G G A T C G T T C C T T G C A A C G T T G G A A G C T A G C T T G G A T G C T T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C G A A G C A T C G T T G C T A G G A T G G A A C C T A C G A T G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +38 T G C T A C G T A C G T T G C T A C C T A G C T A G G T A G G T A C C A A G G A T G C T T G C T A C G A A C G A T G C T A G G T A G C A T C C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A G C T A G G A T G C A T G C A A C C T T G C A A C C T T C G T A G G T T C G T T C C A T C C A A G C A A C C A T G C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G C A A G G T A G C A T C G A A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A T G C A A C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T A C C A A C G T A G G A A C G A A C G A T C C T A C G T A G G T A C G A A C G A T C C A A G G T T C G T A C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G T A G C A A G C A A C G T A G G T A G C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C A A G G T A G C A T C C A A G G T A C G A T G G A A C C T T G G A A C G T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T A C C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G C T T G G A T G C T A C G T A G G T T G G T T G G A A G C A T G C A T C C A A C C T T C C T T C C T T G G T T C C A T C G A A G C T A C G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A C C T A C G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T C G A A C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T T C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T G C T A C C T A G C T T G G T T G G A A G C T A C C T A G C T A G G T T C G T T G C T T G C T A G G A A G C A T G C A A G G A A G C T A C C A T C G T T C C T A G C A A C C T A G C A T C G A A G G A T C C T A G G A T G C A A C C A T G C T T C C T T C G T A G G T A C C A A G C A T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T T C C T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A G C A A C G T A C G T A G C T A G G T A G C A A C G T +39 A G G T A G G A T G C T A G G A T G C T A G C T A G C T A C G T T C C T A G G A T C C T T G C A T G G A T C C T A C G T T G G T A G C T A C C T T G G T A G C T T G G T A G C T T C C A T C G T A G C T T C G T A G C A A G C T A C C A A G C A A C C A T G C T T C C T T G C A A G C T T C C T T G G T T G C T A C G A T C C T A G C A A G G A T C C A T C G A A G G T A G G A A C C T A G C T T C G T A C G T A G G A A C C A A G G A T G C T A G C T A C C A A G G T T C C T T G C T T G C T A G G T T G G T A G C T T C C A A G G T A G G A T G C T T C C A A G G A A G G T T C C A A C C A T G G T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G T A C G A T G C T T C G A A G C T A G G A A C C T A G G A T C G A A C G T T C C A A C C A A G C T T C G A A G C A T G G A A C G T A C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G G A A G C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G G T A C C A T G G T A C G A A G G A T C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G C T T G C T A G C T A C C T T G G A A G C A A G G T T C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G G T T C G T T G C A A C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A G G A A C G T A G C A T C G T T G C A T G G A T C C T A G C T A G C T T G C T A G G A A G G A A G C T T G C A T C C A T C C T T C C A T G C A A C C A A G C A A C C T A C G T A G C T T G C A T C G A A G C A A G C T A G C A A C C T T C C T A G C A A C C T A C G T A C C A T C C T T G G A T G C T T C C A A C G T A C G A A C C A A C G A A C G A A G G T A C C A A C C A A G C A T G C T A G C T A C G T T C G T A G G A A C C A T G G T A C G A T G G T A C C T A G G T A G C A T G C T T C G T A G C A A G G T A G G T T G C T T C G A A C C T A C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G A T G G T T G C A A C C T T C C T T G G A T C C T T C G T A G G A T G C A A G G A T C C T T C C T A C C T A G C T T G G A T G C T A C C T A G G T A C C A T G G T T G C T A G G T A C G T T C C T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G C T T G C A T G G A T G C T A C C A T C G A T C G A A G G A A G C T A G C A A G C T A C C T T G G A A C G A T G C A T G C A T G G A T G G A A G G A A G G A T G C A T G G T A C G A A C G T T G C T T C G T A C G T A C G T T G C A A G C T T G C A A G C T T G C T T C C T T G C T T C G T T G G A T C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C G T T C C A A C C T A C C A A C G A T C C A T C C A T C C T A G G A T G C A A G C A T G G A T C C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C C T T C C T A G G A T G C T T C C A A G C T A C G T A G C T A C C T A G C T A C G T A G G T A G G A A G G T A C C T +40 A G G T A G G T A C G T T G C T A G C T T C G A A G G T A C G T A C G A A G G T T G C T T G C T T G G T T G G A A G C T T G G T A G C T A C C T T G C A A C C T T G C T A G C A T G C T T G G T T C C T T G G T T C C T T G C T A C C A A G G A A C C A T G C T T C G A T G C A A G C A T C G T A G G T T C G A T C G A T C C A A G C T T C C A T G C A T G C A A G C A T G C T A C G A A G C T T C G T A G C T T G C A A G C A A G G A T G C T A G C T A G C A A G C T T C G A A G C A A C G T A G C T T C G T A C C T T C C A T G C T A C G T T G C T T G G A A C G A A G G T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T G C A A C C A A G G A T C C T A G C T T C C T A G G T A C C A A C G T T G G T A G G T A C G A T C C A A C C T T G C T T C G T T C G A A G G T T C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G C T A G C A A C C A A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G A A G C T A G G A A G G A A C G A A G G T T C C A T G G A T C G T A C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G G T T C C T T C C T T C G T A C C A A G G A T G G A T G G A A C C A A G G A A G C A A C G A T G C T T G C T T G C A T C C T A C G T A G G A A G C T T G G A T G C T T C G A T G C T A C G T A G G T A C G T T G C A A G C A A C C T T G C A T G C A T C C T T G G T T C G A A C G A A G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A C C T T G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C T A C G T A C C A T G C A T C G A T C C T A C G A T G G A A G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T T G C A A G C T A C C A A C C A T C G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T A C G T A G G T A G C T A G C T T G G A T G C A T G G T T G C T A G G A A C G T T C C T A G C T A G C A T G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T G C T T G G A A C C A T G C A A G C A T G C A T G G T A C G A T C C T A C C T T C G T A G G A A C C T T C G T T C C T A C G T T G G T A C C T A G C T T C C T T G G A A G C T A C C T A G C T A G G T T C G T T G C T T G C T A G G A A G C A T G C A A G G A A C C T A C G A T C C T T G C A T G C T A C C T A C G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G T A C G T A C C A A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G C A A G C A T C G T A G G T A G G T A G C T A C G T +41 A G C T A G G A T G C T T C C T A C C T T C G A A G G T T G G T A C C A A G G A T G C T T G C T T G G A A C G A T G C A T G G T A G C A T C G A T C C A A C C T T G C T A G C A A G C A T G G T T C G T T G G T A G C A T C G T A C G T A G G A A C C A T G C A T C G A T G C A A G C T T C G A A G G T T G C T T G C A T C C T A G C T T G C A T G G T T C C T T G G T A G C T A G C A A G C T T C G T A C C A A G C A T G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A C G A T G C T T G G A A G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C T A C C A T G C T A C G A A C G T T G G T A C G T A C C T A C G A T G G A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T A G C A T G C A A C G T A G C A T G C T A G C T A G C A T C G A A G G T A C G T T G C A A G C T A G G A A G G T T C G A A G G A A G G T A C C A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A G G A A G G T T G G A A G C T T C G T T G C T A C C A A G G A T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C A A C G T A G C T T G G T T G G A T G G A T G C T A G C T A G G T A C G T T G G A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C A A G C A T C G A T C G A T G C A T G C A A C C A A C G T T G C T T G C T T C C A T C C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T T G G A A C G A A G G T A C C T A C C T A G G T A G C A T C C T A C C A T G C T A G C T A G C A T C G A A G C A T C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A C G A A G G A T C G T A C C A T G G A T C G A A C C T A C G A A G G T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T T C G A A C G A A G C T A C G T T G G T T C C A T G G T A G G T A G C T A C G T A C C T A G C T A G C A A C C T T C C A T G C T T C G T A C C A A C C T T G C T A G G A A G G T T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T T C G T A C C T T G C T T G C A A C G T T G C T A C C A A G C A T G G T T G G A A G C A T C C T A G C T A G G T T C C T A G G T T G C T A G G A A G C T A G C A A G C T A G C T A C C A T C C A A G C A A G C T A C C T A C G A T C C A T C C A A G C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A G G T T C C A T G G A T G C A A G C A A C G A T C C A A G C A A G C T T G C T T G G T T G C A A G C T T G C T T G C T A G C T A C G T A G C T A G C A A G C A A G C A A G C T A G C A A C C T A G C T +42 A G G T T G G A T G C T T C C T A C C T T G C T A G G T A G C T A C C A A G G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A T C C A A G C T A C C T T G C T A G C T T G C T T G G A T C C T A G C T A C C A T G C T A C C A A C G A A G C T T G G A A C G A T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A C G A A G C T T C G T A G C A T G G A T G G T A G G T T G C T A C C T A G C A A C G T A C C T A G C T A G C A A C G T T G G T A G G T A G G A T G C T A C G T A G G T T G G A A C G A A G G T A C C A A C G A A G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C G A A G G T A C C A A C G T A C C T T C G A A C G A T C C A A C G T T G C T T C G A A G G T A G C A A C C T T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C T T C C A A G G T A C C T A G G T A C G T T G C A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G C A A G C A A C G A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G G A A G C T A C C A T G C T T G C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C T A G G T T C G A T G C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A C G T A G C A A C C T A G G T A C G A A G C T A C C T T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T C G A A C C A T G G T A C G T A G G T A C C A A C C T T C C T A C G A T G C T T C G T A G G A T G C T T G G A T C C T A C G T A G C T A G G A A G G T T G C T T G C T T G G T T G C T A G G T A G C T A G G T A C G T T G C A T G C T A G C A A G G T T C C A T G C A T C C T A C C A A C C T A C C T T G C A T C G T A C G T T C G A T C G T T C G T A G C A A G C T A C C T T G C A A C C T T G C A A C C A T C C A A G G T T G G T T G G T A G G A A G C A T G G A T C G T A G G A T G G A T C C T T C G T A G G T A G C T A G C A A G G T T G G T T G C A A G C A A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G A A G C T A C G T T C C A A G C A T C G A T C G A A G C A T C G A T C G T A G G A T G G T T C G A A C G A A G G T T G C T A C G A T G C T T G G A A G C T T C C T A G C T A C C A A C C T T G C T A C C T T C C T A G C T T G C T T C G T T G C A T C G T A G C T A G C T A G C T T G C T A G G T A G G T A G C A A C G T +43 A G G T A C C T A C G A T G C T A C G T A G C A T G G T T G C A A C G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T C C A T C C T T G C A T G G T A G C T T C C A T G G A A C C T T G C A A G C A T C C T A G C T A G G A A G C T T G C A A C G T T G C A A G C T T C G A A G C T T G G T T C C A T C C T A G C A A G G A T C C A T C G A A G G A A G C T A C C A T C G A T C G T A G C A A C C A A C C A A C G T T G C A A C C T A G C A A C G T T G C T A G C T A G G T A G C T T G G T A G C T A G G A A G G T A G G T A G C T T C C A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A T C C A T G C A A C C A A C G T T G G T A C G T A C C T A C G T A C C A A G C A A G G A A C G T A C G A T G C T A G C T A C G T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G G T A G G A A G C A A G C A A G G T T C C A T G G A T C G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A C C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T A G G A A G G T T G C A T C G T A G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G G T T G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A A C G T T G C T A G C T T G C T A G G T A C C T T C C T A C G A A G C T T C C T A G G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G G T A C C A A G G T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C T T G C T T G C A T C C A A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T T G C A A G G T A C C T A C G A T C G T T C G T A G C A T C G T T C G A A C C T T C G T T G C T T C G T A G G T T G C T T G G T T G G T T G C T A G G T T G C T T C G A A C G T T G G A T G C T A G C T T C G A T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A G G T A C C A T C C T T C G A A C G A A G G T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G C A T G G A T C G T A G G A A G G T T C C T T C C T A G G T A C C T A C C T A G C T T C G T T G G A A G C T T C C T A G C T A G G T T C G T A C C T A G C T T G G T A G C T A G G A T C C A A G C T T C C T T C G T T C C T A G C T A C C T A C G T T C C A T C G A A G C T T G G A T C G T A G G A A G G A T C G A A C G A A G C T T C C T A G C T T C C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A G C A A C G T A C G T A G C T A G G T A G C A A C G T +44 A C C A A G G T A C G T T G C T A G C T T G C T A G G T A C G A A C C T A G G T T G G T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T G C T A C C T T G G T A G C A A C C A T G G T T C C T T G C T A G C A T C C T A C G T A G G A A G C T T G C A T C G T T G C T A G C T T C G T T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C C A T G G A T G C T A G C T A G G T T G G T A G G A T G C T A C G A A G G T T G C T A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G C T A C C T A C C A T G G T A G G A T G C T T C C T T G C A T C C A T G C T A C G A A C G T A G G T A C C T A C G A A C C T A G G A A C G T T G G T A C G A A C G A T C C A A C G T A G G T T C G A A G G A T C C T T C G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A A G G T T G G A T C G T T C G A T G C A A G C T T C G T T C G T A G C A T G G T T G G A T C C T T G G T T C G T T C G T A C C A T G G T T G C A A G C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G T T G C T T C G A T C C T A G C T A G G T A C G T A G C A A G G A A G C T T G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G C T A C C A T G C A A C C T A C G T T G C T T G G T T C C T T C G A A C G A A C G A T C C A T C C A T G G A T C C A A C C T T G G T A C G A T C C T A C G T T C C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A C C T A C G T T C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C C T A G G T T G C A A G C T A C C T A C C A T C G T T G G T A G G A T G C A T G G A T C C T A C G A T C C T A G G A A C G A T G C T A C G A A G G A T G C T T G G T T G C T A G G T A C G T A C C T A C C A T G C A T C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C A T G G A T G C T T G G A A C C T A G C T A G G A A G G A A C C A T G C T A C C T T G C A T C G T T G C A A G G T T G G A T G C T T G C A A G C T A G G T T G G A T C G A A C C A T C C T T C C T A C G T T C C A A G G T A G C T T G G A T G C A T G C A A G G T A C C A A G C T T C C T A G G T T G C T A G G A A G C T A G G A A G C A A G C T T C C A T C G T T C C T A C C T A C G A A C C T A C C A T C G A T G G A T C G T T G C T A G C A T G C T A G C T A C G T A G G T A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C G T T G C A A G G T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +45 A C C T A G G T T C C T A G C T A C C T T G C T A G G T A G C T T C C T A G G T T G G T A G C A T G C A A C G A T G C T T G G T A G C T T C C A T C C T A C C T A G G T A G C A T G C A T G G T T C G T A G C T A C C A T G C T A C C A A G G A A G C T T G C A A C G T T G C A A G C T T C C A A G G T T G G T T G C A T C C A A G C A T C C A T C C T T G C A T G G T A G C A A G C T A G C T T G G T A G C A A G C A A G C A A G C T T G C T A G C T A G C A A G C T T G G A A G C T A G C T A G G T T G G T A G G T A G G A A G G T A G C A T G C T A C G A A C G A A G C T T C C A A C C A A G G T A G G T T G C A A C G T T G C A A G C A T G C T A C G A A C G A A C G A T G C T T C G T A G G T A G C A A G G T A G G A A C G T A C G A T G C T A G C T A C C T T C C A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A T G G T A C C T T G G T A C C T A G C A A G C T A G C A T C G A T G G T A G C A A G G A T C G A T G G T A C G T T G C A T C G A A C C T A C G T T G G A T C C T T C C A T C C T T C G T A C C A A G C T T G C A A G G A T C C A A C G A A G G T A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G G T T G G A T C C T A C G T A G G T A C G T A C G T T G G A A C C T T G G T T G C A T C C T T G G A T G G T T G G A A G C A A C C A T C G A T C G A T G C A T C G A A G C A A C C T T G G T T C C T T C G A T G C A A C G A A C G A T C G A T G G A T G G A A G G T A G C T T G C T A G G A T G G A A G G A A G G T A G G T A C G T A G G T T G C T T G C T A C G A T G C T T C G T A G G A T G G T T C C A A C G A T G G T T C C T A C G T A G C A A G C T A G G A A C C A A G C T A C G T T G C T T G C A A C C T A C G A T G G T T G C T A C G A T C C T T C C A A C G T T C C T T C G A A C C A T G G A A G G T T G G T A C C A A G G T T C C T A G G A A C C T T C G T A G G A A G C A T G C A T C G A T C G A T C C T A G G A A G C T T G C T T G C A A C G T T G C T A C C T A G C T T G G T A C G T A C C T A G C T A C C A T C C T T C C T T G C A T C G T A C C A T G C T A C G T T G C A T C G T A C C T T C C A T C C T A G C A A G C A A G C T A C C T T G C A A C G T A G C A A C G A T G C A A G C A A G G A T G G T A G G A A C C T A G C T T C G T A G G A T G G A T C C T T C C T A C G T A C C A A G G T T C C T A G G A T G C A T G C T A C C T T G C T A G G T T C C T T G G T A C G T T C G A A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C T A G C A T C G A T C G A A G C A T C G A T C G T A G G A A G G T T C C T A C G A A G C T T G C T A C C A T G C T A G G A A G C T A C C T T C C T A C C T A C G T A G C A A G G T T G G A A G C A T C C T T G C A T G G A A C G T A G C T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +46 A C C T A C G T A C C T T G C T A G G A T G C T A G G T A C G A T C C A A G G T T C C T T G C T T G G A A C G A A C C T T G G T A G C T A C C T T C C T T G C A T G G T A G C A A G C A T G G T T C G T T G G T A C C A T C G A A C C T A C G T A C C A T G C A A C C T T G C A A G C T T C C T T G G T T G C T A G C A T C G T A G C A A G C A T C C T T C C A T G G A T G C T T C C A A G C T T C G T A C C T T G C A A G C A A G G T T G C A A G C T A G C A A C G T T C C T A G C T A G C T A G G T T G G T A C C T T C C A T G C T A C C T A G C T T G G A A C G T A G C T A C C A A C G A A G C T A G G A T G G T T G G T T G C A A C C A T G C T A C G A A C G T T G G T A G G A A C G A A G C T A G G A A C G T A G G A A C G T A C G A T G C T A G C T T G G T A C G A A G G T T C C A A C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G G A A G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A T C C T A G C A A G C A A G G T T C C T T G C A T G G T T G G A A C C T A G G A T G G A A C G T A G G T T C C A T G C T A C G T A G G T A C G T A G C A A G G A A G C T T G C T T C C A T C C T T G G A T G C A A G C A T G G T A C C A T G C A T C G A T G C A T C C A A C C A A G C T A G C A A G C T T C G A T C G A A C G A A C C A T C G A A G C A T G G A A G G T A C C T T G C T A C G A T G G A A C C T T C C T A G G A A G C T T C C A A G C A T G C A A G C T A G C A T C G A A G C T A C C A T G G T A C G A A G C T T C C T A C G A A C C A A C G A A C G T T C G A A G C T A C G T T G C T T C G T A C C T A C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A G C T A G C T A C G A T G C A T G G T A G G T A G C A T G G A T C C T T C G A A G C T A C G T A C G A T G C T A C C T A C G T T G C T A G G T A G C T T G G T A C G T A C G T A G C T A G C T A C C T T C C T T G C T T C G T A C C A A G C T T G C T T G C A A G G A A C C T A C C A T C C T T C G A A G G A A G C T T C C A A G C T T C C T A G G A A C C A T G C A A G C A A G C A A G G A A G G A A G C A A C G T T C G T T C G T A C G T T C C T T C C A A G C A T C C T A G C A A G G T T C G A T C C A A C G T T C C A A C C A A G C T T G C T A G C A A G C T T C G T A G C A T G C A A G G A A C C T A C C T T C G T T G C T T C C A A C C T A G C T T C G A T C G A A G C T T G G A T G C T A G G A A G G A T C G A A C G A A G C T T C C T A C G A T G C T A G G A A G C T A C C T A C G T A C C A A C C T A G C T T C C T T C C A A G C T T G C T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +47 A G C T A C G T A C C T T C C T A G G T T G C T A G C T A C G T A C C A A G G T T G C T T G C T T G G T T C G A T G C T A G G T A G C A T C C A T C G T A C C T A G C T A G C T T G C A T G G A T G G T T G C T A C C T T G C T A G C A A G G T A G C T T G G A A C G A T G C T A G C A A C G T A G C T T C G A T C C A T C C A A G C A A G G A A C C T T C C T T G C A A G C T A C C A T C G A T C G T A G C A A G C A T C C A A G G T T G C T A C C T A C C A A G C T A C C T T G C T T G C T A C G T T G G T A G G T T G G T A G G T A C C A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C A A C G T A C G A A G G A A C G A A G G T A G G T A C G T A G G A T C C A A C G A T C C T T C G T A G C T T G G T T C G A A G G A A C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C G T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A A C C A A C G A A C C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A A G C A T C G A T G G T T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G G T T G C A T G C A T C G T T G G A T G G T A G G A A G C T T C C A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T A G C A T G C A T G G A A G G T A C C T T G C T A C G A A C G T A C C A A G C T A G G T A C C A A G C T T G C A T G C A A G C T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G T T C G A A G G T A C G A T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T T G G A T G C A A G C T T C C T A C C A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C C T A C G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C A T G C A A C C A T G C A T C C T T G G T T G G T A G G A A G C A A C G T T C G A A G C A A C G A T C C T T C C A A G C T T G C T A C C T A G C A T C C T T G C A T G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A A C C T A C C T T C G T A G C T A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A C G T A G G T T G C A A C C A T G C T T G G A A G C T A C C T T C C T T C G A A G G T T C C T T C C T T G C A A G C T T G G T T G C T T G C A T C C T A G C T A C C T A G G T A C C T A G G T A G G A A C C T A G C A +48 A G C T A G G T T C G T A G C T A C C T T G C T A G G T A C C A A C C A A G G T T G C T T G C A T G G A A C G A A C C T A G G T A C C A A C C T T G C T A G C T T G C T T G C A T C G A T C G T T C G T T G C T A G C A T C G T A C C A A C G T A G C A T G C T A C C A T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A C C A A C G T T G C T A G C T A G G T A G G T T G G T A G G T T G G T T G C T A C C A T G C T A C G A A C G T A G C A T C G A T G G A A G G T T G G A T G C A T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A C C A A G C T A G G T A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A T C G T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G C T T G G A T G G A T C C T A G C A A G C A A G G T A C C T A G C A T G C A T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G C T A C C T T G C T T C C T T C C T T C C T T G C A A G C A T G G A A C C A T G G A A G G A A G C A T C C A A C C A A G C T T C C T T G C T T C C A T G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A C G T A C C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G A A G G A A C G T A C G A T G C T T C G A A G C T A C G A T G G A A C G A A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A C C T A C C A A G C T A C C T A C C A T G G T T G C T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A T G C A A G C T A G C T A G C T A C C T T G C A A C C A T G C A T G G T T G G A T G G A A G G A A G G A A G C T T G G A T C G A A C G T A C C T T C C T A G C A T G C T A C C T A G C T T C G A T C C A T G C T A C C T A G C T A G G T T C C T A G G T A C G T T C G T A G C T A G G A A G C T A G C T A C C A T C G A A G C T T C C T A C C A A C G A T C C A T C G A T G G A T C G T T G C A A G G A T C G A T C G A A C G A A G G T T C C A A C C T T C C T T G G A A G C T A C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G C T T G C T A G C A A C G T A G G T A G G A A C C T A C C T A G G T A G G T A G C A A C G T +49 A G G A A C G T A C C T T C C T A C C T T G G T A G G A A G C T A C G A A G G T T G C T T G C T T G G T T C G T A C C T T G G T A G C A T C G A T C C T A C C T T G G T A G C A A C C A T G G T T G G T A G C T A C C A T G C T A C C A A G C A A G C T T G C A A C G T T G C A A C C T T C C A A G G T T G C T T G C A T C C T A G C A T C C A T G C T T C C T T G G T A G G A T C G A A G C T T G G T T G C T A G C A A G C A T C G A A G G A A C G T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T A G G A A G G T T G G T T G C A A C C A T G C A A C C A A G G T A C G A T G C T T G C T A C C T A C G T A C G T T G G T A G G T A C G A T G C T A C C T T G C T T C G T A C G T A C G A A C G T A G G T T C G A A G C T T G C A T G C A T G C T T C C T T C G A A G G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A C G T A C C T T G G T A C C T T G G T T G C A A G C T A C C T T G G T A G C A A G G T T C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G C T T C G A A G C T T C G T A C C A A C C T A G G A A G C T A G C T A G C T A G G A A G G T T G C T A C G A A G G T A G C A T C G T T G C A T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G G T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A C C A A G C T T C G A A G C T T C C T T C C A T C G A T G C A T G G A A C C A A C C T T G C T A C G A T C G T T C C T A C C T T G G T A C C A T G C T T C C A T G C A A C C T T G C A A G G A A G C T A C C T T G G A A C G A T G G T A C C A A C G T A G C A A G C T A C G A A G C T A G G T A C C A A C C T T G C A T C C T T C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C G A T G C T T G G T A G C T A C C T T G G A T G G T T G C A T G G T A G G A T G G T A C G T T G G A T G C T A G C A T G C T T C C T T G C T T C G T A C C A A C C T T G C T A G C A A G G T A C G T T C C A T C C T T C G A A G G A A G G A A C C T T G C T T C C T T G G A A C C A T C G T T C C T T G G A T G G A A G G A A C G A A C C T T C G T A G G A A C G T T C G T T C C T A C C A T C G A A C C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C C T T G G T T G C T T C G T A G C T A G C A A C G A A C G A A C G A T C G T T G G T A G G A A C C T A C G T T C C A T C C A T G C T A G G A T G C T A C G A A G G A T C G A A C G A T G C T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C A A G C T T G C T T C C T T G G T A G C T T G G T T C C A A G G A A C G T A G C T T C C A A G C A A C C T A G C T A G C A A C G T A C C T +50 A C C T A C G T A C C T T G C T A G G A T G C T A G G T T G G T A C C A A G G A T C C T T G C T T G G A T G G A T G C T A G G T A C C A T G C T T G C T T G C A T G G T A G C A T C C A T G G A A G G T T G C T A C C A T C C T A C G T A G G A A C C A T G C T T C G T T G C A A C C T T C G T A C C T T G C T T C C A T C C A A G C A A G G A A C C T T C C A T G G A A G C T A C C T A G C T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C C T T G G A A G C T A C C T A G G T T G G T A G C T T G G A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A T G C T A C C T T G C A A C C A T C C A A G G A A C G A A C G T T G G A A C G A A G G T A C C A A C G T A G G A T C C A A C G A T G C A A C C T A C C T T C C A A G G A T C C A A C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C G T A G G A A C C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T G C A A G G T A G C A T G C A A G G T A G C T A G G A A C C T T G G A A G G T T C G A A G G A A G G T A C C A A G G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G C T T C C A A G C T T G G A T G C A T C C T A C G A A C C A A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T C G T A G G T T C G A T C C T T C C T A G G T A C G T A C G A T G G T A C C T T G G T A G C T T C C T T G G T T G G T A G G A A G G A A C C T A C G A T C G A T G C T T C C A A C C A A G C A A G C A T G C T T C G T T C G A A C G A T C G T A G C A A G C T T G C T A G C A A C C A A C C T A C G A T C C A A C C T T G G T T G C T A C C A T G G T T G C T T G C A A C C T T G C A T C G A T G C T T C C A T G G T A C G A T G C T T C G T A G C A A C C A A C G T A C C T T C C T A G G T A C C A T G C A T C G A T C C T A C G T A C G T T G C T A C G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C T A G C A A G G A A C C T T C G A T C C T A C C A A C C T T G C T A G C A A G G T T C G T T G G A T C G T A C C T T G G A A G C T A C C T T C G T T C C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A A G G A A C C T T G G A T C G A A G C T T C C T T C C T A G C A T G C T A G C T A G C T T G G T T C C A A G C T A C G T A G G T T C G A A C C T A G G T T G C A T G C A A G C T T G C A A G G A A G C T T C C A T C C A T G C A A C C T A C C A A G C A T C G A T C G A A G C A T C G A T C G T A G G A T G G T T C C T A C G A A G C T T G C T A C C A T G C T A G G A A G C T A C C T T C C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T A C C A A G C A A G C T A G C T A G G T A G C A A C G T +51 T G C A A C G T A C C T A G G A T G G T A G C T A G C T A C G T A C G A A G G T T G C T T G C T T G G A A C G A A C C T A G G T A G C A A C C T T G C T T G C T T G C T T C C T T G C A T G G T T G G T T G C T A G C A T C G T A G C T A C G T A G C A T C C T A C C A T G C T T C C T T C C T A G C T T C G T T G C A T C C T A G C A T C C A T G C A T C G A T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C C T T G C T A G C T A G G T A G G T T G G T A G G T T G G T T G G T A C C T T C C A T G G A A C G A A C C T T G C T A C G A A G G T A G G A T G C A A C G T T G C A A C C T T G C A A C C A A C G T A C G A A G G A A C G A A G G T A C C T A C G T A G G A T C C A A C G A T C C T T C G T A G C T T C G T T C G T T C C T T C G A A C G T T G G A T G C T T G C A T G G T T G C A T G G A A C C A T G G A T G G A T G G T A G G T T C G A A C C A A C C A A G C T A C C A A C C T A G C A T C G T A C C A T G C A A C C T T C C A T G C T T G G A T C C T T G G T A G G T A G G A T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G C A T G G A T C C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T A C G T T G C T A C C T A G G A A G C T A G C T T G C T T C C A T C C T T G G T T G C A A C C A T G G T T C C A T G C A T G C T A G C A T C G A A G C T A C C T T G C T T G C T T C C A T C C A A C G A A C G A T G C A T G C A T G G A A G G T A C C A A C G A A G C A A C C A A C C A A G C T A G G T A G C T T G C T T G C A T G C A A G C T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A G G A A C G T A C G T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T C C T A G G T A C G T A G G A T G C A A G C T T C C T A C G A T G C T T C G T A G G A T C G T T G G T A G C T T C G T A C C T A G G A A C G A T G C T T G G T A C G T T G C A T G G T A G C T A G G T A C G T A C C T A C C A T G C T A C G T T C C A T G C A T C C T A C C A A C C T T G C T T G C T T G G T T G G T A C C A T C C A T C G A A G C A A G C T A G C A A G C A A C C T T G C T A C C A A C G T T C C T T G G A T G G T A C C A A G C A A G C T T C G A A C G T A C G A T C C T A C C T A C G T A G C T T G C T A G C T T C G T T C C A T G C T A C C T A G C T A G G T T C C T T G G T A C G T T C G T A G C T A G G A A G C T A G C T A C C A T G C A A G C A A G G T A C G T A C C A T G C A T C G A A G C A T C G T T G C A A G G A T C G A T C G A A C G A A G G T T C C A A C C T T G C T T G G A A G C T A C C T T C C T T C G A A G G T T C C T A C C T T G C A A G C T T G C T T C C T A G C A T C C T A G C T A C C A A G C T A C C T A G G T A G G T A G C A A C G T +52 A G C T A C G T A C C T T C C T A C C T T C G A A G G T A C G T A C C A A G G T T C C T T C C A T G G A A C G A T C C T A G G T A C C A T G C T T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T C G T A C C A A C G T A G C A T G C A A C G T T G C A A C C T T C G T A G C T T C G A T C C A T C C A A G C A A G G A A C C T T C C T T G C A A G C T A C C A A G C T A C G T A C G A A G G A A C G A T G G A A G C T A C C T A C C A A C G T A C C T A G C A A G C T A G G T T C C T A G C T A G G T T G C T A C C A T G C T A C G A A C G T A G C A T C G A T G G A T G G T T G G A T G C T T G G A T G C A A C G T T G G T A C G A A C G A A C G A T G C T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C C T A C C T T G G T T C G A A G G A A G G T T G G T T C C T T C C A T C G T A C G T T G C T A C G A A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T G G A T G G A A C C A A C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G G A A G C T A G G T T G C A T G C A T C G T A G G T T G G T A G G A T G G A A C C A T C C A A G G A A G C A T G C A A C C T A C C T A C C A A G G T T C G A A G C T A C G A A C G T A G C A A G C T T G C A T G G T T C C T T G C T A C G A A C G T A G G T T G G T A G G T A C C A A C C A A G C A T G C T A C G T A C G A T C G T A G C T T C G A T G C A A C G A T G G T T G C T A C G T A G C A A G C T A C G A A G G A A C G T A C C A T G C T T C G A A G C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T G G T T C C T A G G A T G C T T C G A A C C T T C G T A G C T A C G T A G G T T G G T A C G T A G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C G A A C C T T G C T A G C A A G C T A G C T A G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G T A G G A T G C T T G G T T C G A A G C A A C G T A C C T T C C A A G C A T G C T A C C T A G C T T C G A T C C T T G C T T C C T T G C T A G G T T G G A A C C A A C G T T C G A A G C T A G G A A G G T A C G A T C C T T C G T T G C T T C C T A C G T A C G A T C C A T C C A T G G A T C G T T G C A A C G A A G G A T C G A A C G A A G G A T G C T A G C T T G C T T G C A A C C A A C G A T C C A A C C A A G C T T G G A T G G T T G C A A G G T T G G T T G C T T G C T T C C T T G C T A C C T A G G T A C C T A G G T A G G A A C C T A G C A +53 A C C T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T C C A A G C T A C C T T G G T A G C A T G C T T G G A T C C T T G G T A G C A A C G T T G C T A G G A A G C T T G G A T C G T T G C A A G C T T C G A T G G T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C A T C G T T C G T A G C T T G C A A G C A A G G A T G C A A C C T A C C A A C C T T G C T A G G T T G G T A G G T T G G T A G G T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A C G A A G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T A C C A A C G T A G G A A C G T A C G A T G C T A G C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C T T C C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A G G T A C C A A G C T T C G T T G C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A G G A A C G T A G C A T C G T T G C T T G G A T C C T T G C T A G C T T G C T A G C A A G G T A C C T T G C A T C C A T C G T T C G T T C G A A C G A A G C T A C C A T G C A T G C T T G C A T C C A A C C T A C C A A G C A T G C T T C G A T G C A A C G A A C G A T C G A A G C A T C G A T G G T T C C T T G G A A G C A A C C A A C C T A G G A T C C T T G G T T C C A A C C A T C C A A G C A T G C A A C G A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G T A G C T T G G T A C G T T G C T T C G A T C C T A G G A A G G T T G C A A C G A T C C A A G G A T G C T T C C T T C G A A C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T A C C T A C G T T G G A A C C T T G G T T G G A T G C A A G G T T G C T T G G T A C G T T C G T T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C A A G G A T G C T T G C A T C C A T G C T A G C T T G G A A C C A T G C A A C G T A G C A A C G A T G C A T G C A T G G A T G G A A G G A T G C T A C C T T G G A A G G T A C G T T C C T T C C T A G G T A C C T A C C T A G C T T C G T T G G A A G C T A C G T T G C T T C G A A C C T A G G T T G C A T G C A A G C A T G C A A G G A A G C T A C C A T C G T T G G T A C C T A C C T A C G T T C C A T C G A T G C T T G G A T G C T A C C A T G G A A G C T A G G T A G G A T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G G T A G C T T G G T T C C T T G G T T C C T T C C T T G G A A C G T A C G T T G C T A G G A A G C T A G G T A G G T A G C A A C G T +54 A G G T A C G T A C G A T G C T A C G T A C C T T C G T A G G A A C G A A G G T T G C T T G C T T G G A A G G A A G C A A C C T A C C A T G C T T G C T T G C A T G G T T G C A A C C A T G G A T C C T T G C T A C C A T G C T A C C A A C G A A G C T T G G A T C G T A G C A A G C T T C G T A G G T T G G T T C C A A C C A A G C A T C C A T G C A T C C A T G G A T G C T A C G A A G C T T G G T A G C A T G G A T C C A A G G T A G C T A G C T A C G A A C G T T C C T A G C T A G C T A G G T T G C T A G C T T C C T A G G T A G G T T G C T A C C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C T T G C A A C C A A G G T T G G T A C G T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A T C C A T C C T T G C T T C G A A G C T A G C A T G G T A G C T T C G T T C G A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T A C C A A C C A A C G T T C C A T C C T T G C T A G C A T C C A A G G T A C G A T G G A A G C T T G G A A G G T A C G A A G G A A G G T A C C A A G G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C A T C C T T G G T T C C A T G G T T G G A T G C A T C C T A C G A A G C A A G G T T C C A A C C A T G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C T T G C A T G C T T G C A T C C A T C C T T C G T T G C A A G C A T G G T A G C A T G C A T G C T T G C A T C C A A C C A A G C T T G C A T G G T A C G T A G C T T C G A A C G A T C C A A G C T T G C A A G G T A G C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G A A G C T A C G T A C C T T G C A T C G A A G C T T C G A A C G T T G C T A C G A A C C A A G G A T G C T T C C T T C G A A C C A T G G T A C G T A G G T T G C A A G C T A C G T A G G A T G G T T C G T A G G A T C G T T G G A A C C T T C G T A G C T A C G T A G C T A G C T A C C T A G G T A C C A T G G T A C C T T G G T A C G A A C G T A G C T A G C T A G C T A C C T A G C T T C G T A C C A A G C T A C G T T G C A A G G T T G C T A C C A T C C A T C G A A C G A A G C T A G C T T G C T A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A T G C A T G G T A G G A A C G A T C C T T G C A T G G T A C C T A C C T A G C T T G G T T C C A A C G T T C C A A G G T T C G T T C C T T G G T T G C T A G G A A G C A T G C A A G G A A G C T A C C A T C G T T G C A A C C A A C G T A C G T T C C A T C C A T G C T T G G A T G C T A G G A A G G A A C G T A C G A T G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C G T T G C A T G C T T G C T T G C T A G C A A C G T A G C A T G C A A G C A T C C T A G C T A G C A A G C T A C G T +55 A G G T A C G T A C G A T G C T A C G T A C C T T C G T A G G T A C G A A G G T T G C T T G C T T G G T T C G A T C C T T G G T A G C A T C C A A C C T A C C T T G G T A G C T T C C T T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A C C T T C G A A G G T T G G T T C C A A C C A A G C A T G C A T C C T T C C A T G G A A G C T A C G A A G C T T G G T A G C A T G C A A G C A A G G T A G C A A G C T A C G A A C G T T C C T A G C T A G C T A G G T T G G T A C C T T C C T T G C A A C G T A G C T A G G A A C C A A G C T T C C A A C C A A G G T T G G A T G C T A C G T T G C A T C C A T C C T A C C A A C G T T C G T A C C T A C C T A G G T A G G A A G C A A G G A A C G T A C G A T G C T A G C A A C C T T C C T A C G T A G G A A C G T T G C T T C G T T C G T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A A G G A T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T T G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G A A G C T A G G A T G G T T C G A T C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T T C G T A G C T A C C T A G G A A G C T A G C T T G C T T C C A T C C T A C G T T C G A A G G A A C G T A C C A T G C A T C G A T G C A T C C A A C C A A G C T T G C A T G G T A C G T A G C T T C G A A C G T A G C A A G C T T G C A T G G T T C C T T G C T A C G A A C G T A C C T A G G T T C C T T G C A A C C A A G C A T G C A A G C T T G C A T C G A A G C T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G C T A G G T A C C A T G C A T C G A A G C T T C G A A G G T T G C T A G C A A C C T A G G A T C C T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C T A G G A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T A G G A A G G A A C C T A C C T T G G T A C C A A G G T A G C T T G G T A C G T A C C T A C C T T G C T A C G A A C C T T G C A T G G T T G C A A C C T T G G T T G C A T G G A A C G T A G C A A C C T A C C T T G C A A G G A A C C T A G C T T C C T T G C A A G C A T G C A T G G T T G G A T G G T A C G A T G C T T G C T T C G A T C G T A C C T T C C T T G C A A C G A T G C T A C C T A G C T T C C T T G G T A G C T A C C T A G C T T G G T T C G T T C C T A C G A T C G T A G C T A G C A T C C A A C C T A C G T T G G T T G C T T C C T A G C T A C C T T C C A T C G A T G C T A G G A T G C T A G G A T G G T T C C T A C C A A G C T T G C T A C G T A G C A T G G A A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +56 A G G T A G G T A C G T T G C T A G C T T C C T A G C T A G C A A G C A A G G T T C C T T G C T T G G A A G G A A C C T A G G T A G C A T C G A T G C T A C C A T G G T T C C A T C C T T G G A A G C T T G C T A G C A T G G T A C G T A G G A A G C A T C C T T C G A T G C A A C C T T C G T A G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G A T G C T A C G A T G G T T C G T A G C A A G G T T G C A A G G A T G C A A G C T A G C A A C C A T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G T A G C T A C C A A C G A A G C T A G G A T G G T T G G T T G C A T C C A T G C A A C C A A G G A T C C T A G C T A C G A A C C T A G G A A C G T A G G A A C G T A C G A T G C A A C C T A G C T A C G T T C G A A G C A A G G T T G G T T C G A A G C T T G G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T C C A T C G A T G G T A G C T T G G A A G G T A G C A T G G A A G G T A G G A A G G T T C G A A G G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T T C C T T C G A A G G A A C C A A G C T A C C T A G C A A G G T T G C T A G G A A G G T T G C A T C G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A G C T A C C T T C C T T G C T T C G A T G C A A C G A A C G A T C G A A G C A T C G A A G G T A C C A A C G A A G C A A C C A A C C A A G C A A G G T A C G T T G C T T C C A T C C A A G C A T G C A A C G A A G G A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A C G A A C G T A C C T T G C A T C G A A C C T T C G A A G G T T G C A A C G A T C C A A G G A T G C T T C C T T C G A A C C A T G G T A C G T T G G A T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A C C T T C G T A G C T A C G T T G G A A C C T T G G A T G G T T G C A A G G T T G C T T G G T A C G T T C G T A G C A T G C T A G C T A G C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C A T C G A A C G A A G C T A C C T A G C T T G C T T G C A A C C A T G C A A G G T T G G A T G G T A G G A T C C A A C C T T C G T A C G A A C G T T G C T T C C T A C G T A G G A A G C A A G G T T G G A T G C A A G C T T C C T A C G T T C G T T C C T A C C T T G C T T C G T A G C T A G C A A G C T A G C T A C C T T C G T T G C A A G C A A C G A A C G A T C G A T C G A T G C T T G G A T G C T A G C A T G C T T G C T A C G A T G C T T G C T A C G A T G C T A G G A A G G A T C G T T C C A A C C A T C C T T G C T A G G T T G C A A G C T T G C T T C C T A G C A T C C T A G C A T G G T A C C T T C C T A G C T A G C A A G C T A C G T +57 A C C T A G G T T C C T A G C T A C C T T G C T A G G T A G C T A C C A A G G T T C C T T G C T T G G T T C G A T C C T A G G T A G C A T G C T T G C T T G C T T G G T T G C A T C G A T G G T T C G T T G C T A C C A T C G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C G T A G G T T G G T T C C A A C C T A G C A T G C A T G G T T C C T T G G A T G C T A G G A A G C T T G G T A G C A T G G A T G C A A G G A T G C A A G C T A G G A A C G T T C C T T G C T A G C T A G G T T G C T A G C T T C C T A G G A A C G T A G C T T G G A A C C A A G G T T C C A A C G A A G C T A G G A A G G T T G G T T G C A A G C A T G C T A C G A A C G T T G G T A C G A A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C A T C G A A G G T A G C A A G G T T G G T T C C T T C G T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A A G C T A G C A A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T C G T A C C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G T A G C T T C G A T C C T A G C T A G G T T G C T A G G A A G G T A C C T T G C T T G C A T C G T T G G T T G C A A C C A T G G T T C C A T G G A A G C T T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C G A A C G A T C G A A G C A T G G A A G G T A C C T T G C T T C G A T C C A A C C T T G G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A G C A A C C T A C G A A C G A A G G T A C C A T G G A T C G A A G C T T C G A A G G T T C C A A G G A A C C T A G G A T G C T T G C T T G C A T C C A T G G A A C G T A G G T T G C A A C C T T C C T A G G A T C G T T C G T A G G A T G C T T G C A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A A C C T T G G A T C C T A C C T A C C T A G G T A G C T A C C T A C G T A C C A T C C T T C G T T C C A A G G A A C G A A G C A A C C T T G G A A C C A T G C A A G C T T G G T T G C A A C G A A C C T A C C T T G G T A C G T A G G T A C C T T C G T A C G T A C C T A G C A T G G T T C G T T G G A A G C T T C C T A G C T A G G T T C G T T C C T T G C T T C G T A G C T A C C A A G G A A G C T A C C A T G G A A G C A A C C T A C C T A C G A T C C A T C C A A G C T T G G A T G G A A G G A T G C T T C G A A C G A T G C T T G C A A C C A T G C T T G G A A G C T T C C T A G C A A C C A T C C T T G C T A C C T T G C A A G C T T G C T T C C T A G G A A C G T A G G T T G G T A C C T T C C T A G C T A G C A A G C T A C G T +58 A C C A A C G T A C C T T C C T A C C T T C G A A G G T A C G T A G G A A G G T T G C T T G C T T G G A A G G A A G C T T G G T A G C A T C C T T G C T T G C T T G C T A G C A A G C T T G G A T C C T T G C T A C C A T G C T A C C A A C G T A C G A T C G A T C G T A G C A A G C T T C C T A G G T T G C T T C C A T C C T A G C A T C C A A C C T T C C T T C G A A G C T A C G A A G C T T C C A A G G A A G C A T G C A A G G T A G C T A G C T A C C A A C G T A C C T A G C T A G C T A G G A T G G T A G G T T C C T A G G T A G G T T G C T A C C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A C C T A G G A A C G T A C G A T G C T A C C T A C C T T C G A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A T C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G C T T G C A A G G A T C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A T G G A A C C A A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T T C G T A G G T T G G A T C C T T C G T A G G T A C G T A C G A T G G T A C G A T G G T A G C T T C C T T C C A T G C A A G C A T G G A A C C A T G C A T G C T T G C A T C C A A C C A A G C T A G C T T G C T T C G A T G C A T C G T A C G T T C G A A G C A T G G A A G G T A C C T T G C T A C G A T C G T T C C T A C C A A G G T A C C T T C C T A G C T T G C T A G C T A C G A T C G T A G C T T G G T T G G A T G G A A G G T T C G T A G C A A C C A T G C T T C G A A G G A A C G T A C G A A G C T T G C A A C C T A G G T A C G T T G C T A C G A A C C A A G G A A C G T A C C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T T G C T A C G T A G C T T G C T T G G A T G G A T G C A T G G T A G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A A G C A A G C A A C C A A C C T T G C T A G C T A C G T T G C T A C C A T C C A T C G T T G C A A G C T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G G A T G C A T G G T A G G A A G G T T C C T T G C A A C G T T C G A A G C T T G C T T G G A T C C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C A T G C A A G G A T G C T T C C A T C G T T G C A A C C T A C C A A G G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G A A G G T T G C T A G C T T G C T T G G T A C C A T C C T A G C T A C G T A C C T A G C T A G G T T C C A A G C T T G G T T G C T A G C A T C C T A G C A T C C A A G C A A C C T A G G T A G C T A C G T A C G T +59 A G G T A C C T A C G A T G C T A C G T A C C T T G G T T C C A A G C A A G G T T C C T T G C A A G G A A C G A A G C T T G G T A G C A T G C T T C C T T G C A T G G T A G C T T C C A T G G A A C C T T G C A A G C A T C C T A C G T A G G A T G G A T G C A A C G A T G C A A G C T T C C A A G C T T G G T T C G A T C C T A G C A A G G A T C C T T C C A A C G A A G C T A G C T A G C T T G G T A C C T T G C A A C G A A G G T T G C T A G C T A C C A A C G T T G G A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G A A G C T A C C A A C G A T G G T A G G A T G G T T G C T T G C A A G C A T G C A A C C T A G G T A G G T A G G A A C G A A G G T A C C A A G C A T G G A A G G T A C G A T C C T T C C T T C C T T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T T G C A T C C T A G C T A G C A T C G A A G G T A G C A T G G A A G C T T G G T T G C T A G C T A C C T T G C T T G C A T C G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G C T A G C A A G C T A C C T A G C A A G G T A C C T A C G A A G G T A G C T T G G T T G G A T G G A T G C T T G C T A G G T A C G T A G G A A G G A A G G T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A G C A A C C T A C C A A G G T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G G T T C C T T G C T T C G A T G G T A C C T T C C A A G G T A C C A T G C T A C G A T G C T A C C T T G C A T C G A A G C T T C C T T G G A A C G A A G C T A C C T A C C A A G C A A G C T A G G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A C C T T G C A T C C A T G G A A G C T T G G T T G C A A G C T A C C T A C C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G A T G C T A C G A T G G T A C C T A G G T T G C T T G G T A C G T T C G T T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C T T C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G G T T G G T A G G A A C C A A C G T T C C A T G G A T G G A A G G A A G C T T G G A T G G T A G C A A C G T T C C T T G C A A C G T T G G A A C C T A G C A T C C T T G G T A G C T T C C T A G C T A G G T T C G T A G C T T G C T A C G A A G C A T G C A A G G A A G G A T C C T T C G T T G C A A C G T A C C A A G C A T C C A A C G A T C C T T G G T T G C A A G G A A G G A T C G A A C G A T G C T T G C T A G C T T G C T T G G A A G C T T C C T A G C T A C C A T C C T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A T G C A T G C T A G C A T G C A A C C A A C G T +60 A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C A A C C T T G G T A G C A T G C A T G G A T C C T T G G T A C C A T C C T A C G T A G G T A C C A T G C A A C G A T G C A A G C T T C C T T G G T T G G T T C G A T C C T A G C A A G G A T C C T T C C A A C G A A G C T A G C T A G C T T G G T A C C T T G C A A G C A A C G T T G C A A G C T A G C A A C G T A C C A A G C A A C G T A G G T T C C T A C C T A G G A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C G A A G G T A G G T A C G A A C G T T G C T A C C T T G G T T C C T A C G T A C G T A G C T A C C T A G C A T G G A A C G T A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T A G G A T G C A T C C A A C G A A G C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A C C A T G C T T G C A T C C T T G G T T G C A A C C A T G C T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A C C T A C G T T G C A A C C T A C G T T C G A A G C T A C C A T G G A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G G T A C C T T C G A T G C A A C G T A G G T A G C A T G G A T C C T T C G T A G C T A C G A A C G A T G C T T G G T T G G T T G C A A G G T T G C T T G G T A C G T A C C T A C C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C T A G G A T G C T T C C A T C C T T C G T A G G A A G C T A G C A A G C T A C C T T G G A A C G A T G C A T G G T T G G T T G C T T G C T A C C T A C C T T G G A T G G A A C G T T G C T T C C A A G C A T C C T A G C T A G C A T G G A T G C A A G C A A C G T T G G T T C G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A G G A A C C T A C G T A C C T A G C A A C C T A C C A T C G A T C G A A G C A T C G A T C G T A G G A T G G T T C G A A C G A A G G T A C C T A G C A A G C A T G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C C A A C C A A C C T A G G T A G G T A G C A A C G T +61 A G C T A G G A T C C T A G C T A C C T T C G A A G G T T G C A A C G A A G G T A G G A T G C T A C G T T C G A T G C T T G G T A C C T A C C T T G C T T G C A T G G T T G C A A C C A T G G T T C G T T G C T A G C A T C C T T C C A A C G T T G C A T G C A A C C T T G C A A C C T T C G T T G C T T C C T A C C A T C C T T G G T T C C A T G C A T C C A T G G T A G C T A C G A T G C T A C C A A C G T A G C A A G C A T C G A A G G A T C C A A C G A T G C A T G G A T G C T A C G T A G G T T C C T A G G T A G G A A G G T T C C T T C C A T G G A A G G T A G C T A C C A A C C A A G G T A G G T T G C A A G C T T G C A A C C A T G C A A C C A A C G T A C G T A G C T A C G A A G G T A C C A A G C A A G G T A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T T G C T T C C T T G G T A G C A T C C A A G G T A C G A T G G A A G G T A G G A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A C G T A C C A A G C T T C G T T C C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T T G C T A G G T A C C T A G C A A G C T A G C T T G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G G A T G C T T C C A T C G A A G C A A C C T A G C T T G C T T C G T A G C A T C G T T C G T A C C A A G C A T G G A A G G T A C C T T G C T A C G A T C C T T C C T A C C A A G G T A G C A T G C T T G C T T C C A A C C T A G C A T C G A T G C A T C C T T G G A A C G A A G C T A C C T A C G T A G C A A C C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G G A A G G T A G G T A G C A A G C A A G G T A G G A T C G T T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T A G G A T G C T A C C T T G G T A C C T A G G T T G C T T G G T A C G T T G G A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T T G C T T G C T A G G T A G C T A G C A T C C T T C G A T G C A A C C T A G C T A G G T T C C T T C C A A C C A T G C A T G G T T G C A T G G T A C G A T G C A A C C T T C G T A G G A A C G T T C C T T C C T A C G T A G C T A G C A T G C T T G G A T G C A T C G T T C C A A G G T T C G A A C C T A G G T T C G T A G C A A G C T T G G A A G G A A C C T A C C T T C G T T G C T T C C A A C C T A C G A T C C A T C C A T G C T A G G T T C C A A G G A T G C T T C C T A G G T A G G A T G C T A C C T T G C T T G G A A G C A T C C A T G G A A C C A A G C T T G C A A C G T T G C T T G G T T C C T T C C T T G G A A C G T A C G T T G C T A G G A A G C T A G G T A G G T A G C A A C G T +62 A G G T A C G T A C C T A G G A T G G A T G C T T G G T A C G A A C C A A G G T T G C T T G C T T G G A A G G A A G C T A G G T A G C A T G C A A G C T A C C T T G G T A G C A T G C A T G G T T C C T T G C T A C C T T G C T A C C A A G G A A C C A T C G A A C G T T G C T A G C T T C C T T G C T T C C T T C C A T C C T T G G A A G G A T C C T T C C A T G G T A G G A T G C A A G C T T C G A A G G A T G C T A C G A A G G T A G C T A C G T A C G A T G G A T C G A T G C T T G C T A G G T T G G T T G G T T G G A A G G T A G G A T G C T A C G A A C G A A G G T T C C A T G G A A G G T A G G A A G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A C C T A C G T A C G A A G G T T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T T G C A T G C A A C G T T G C T T C C T T G G T A G C A T C C A A G G T A C G A T G G A A G G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A C G T A C C A A G C T T C G T T C C A A C G T A G G A A G C T A G G T A C C T A G C A A G G T T G C T A G G A A G G T A G C A A C G T T G C A T G G A T C C T A C G T A G G T A C G T A C G A A G G T A G C T A G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C A T G G T T C G A T C G T T C C T A C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T G C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G A T G C T T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A G G T T G G T A C C A A G G T A C G T A C G A T G G T T C G T A G G A T C G T T C G A A C C T T C C T A G C T A G G A A G G A A G C T T G C A A G G T A C C A T G G T A C C T T G G T A C G A A C G T A G C T A G C A T G G T T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C C T A G G T A C C A T C C T T G G A A C G A A G C T T C C A A G C T T G C T T G C A A G C A T G C A T G G T T G G A T G G T A G G A A G G A T G G T T C G A A G G A A G G A T C C T T C C A A G C T T C C A A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T T G G T A C G T T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C C T A C C A A G C A T G C A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C G A A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C T A C C T A G C T T G C T A G G A A C C T A G C T A C C A A C C T A G C A +63 A C C A A G G T A C G T A G G T A G C T A G C A A G G T T G C T A C G A A G G T T G G A T G C T T G G T T C G A T G C A T G G T A G C A T G C T T G C A A C C T T G C T A G C A T C G A T G G A A C G A T C G T A G C A A C G T T G C T A C G T A G C A T C G A T C C T T G C A A C C T A C G T A C C T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C A A G C T T G G T A G C T T G C A A G C A A G C T T G C T A C C T A G C A A C G T T C C T A G C T A C C T A G G T T G G T A C C A T G G T A G C T A C G T A G C T A C G A A C G A A G G T T C C A A C C A T G G T A G G T T G C T T G C T T G C T A C C A T G C A A C C A A G G T A C G A T G C T T C G A A G G T A G C A A G C T A G G T A C C T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T T G C T A G C A A C G T A G C A A G G T A G C T T G C A T G C A T C C T A C G T T G G A A C G A A G C A A C C T A C G A T C G A T G C A T G C A A C C A A G C T A G C T T G C T T C G T T C C T T C C T T C G A T C C A T C C A T G G A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T A C C T T G C A A C G A T G G T A G G T A C G T A C C A A C C T T C C T T C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T T C G T A G C A T G G A T C G T A G G A T G C A A G G A T C C T T C G A A G C A T G G A A G G T T G G T A C G T A G G A T G C A T C C T T G C T T G G T A C G T T C C T T G C A T G C A T G G T A C C A A G C A T G G T T G C T A C C T A C G T T G C A A G G T T G G T T C C A T C C A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T C G A T C G T T C G T A C C A T C C T T C C T A C G T T C C T A G C T T G C T T G G A T G C A T G C A A G G T A C G A A G C T T C C A T C C A A G G T A G C A A G C T T G C A A G C A A C G A A C C T A C G T A C C T A G C A A C C T A C G T T C C A T C G A T G C T A G G A T G C T A C G A T G G T T C C T A C C T T C C A A G C T A G C T T G C T A G G T A C C A T C C T A G G T A C C A T C C T T G C T A G G T T G C A A G C T T G G T T G C T T G C A A C C T A G C A A G G T A C C T A G C T A G C T A G C A A C G T A C C T +64 A C C T A C C T A C G A T G C T A C G T A C G A T G G T A C C T T C C T A C G T A G G A T G C T A C G T T G G A T G C T T G G T A G C T A C C T T G C A A C C T T G G T T G C A A G C A T G G T T G G T A G G T A G C A T C G T A C C A A C G A A G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T A G C A T C G T A G C A A G G A T G C A T C C A A G G A A G C T A C G A A G C T T C G T A G C T T G C A A G C T A G G T T G C T A G C T A G G A A C G T T C C T T G C T T G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C A A C G A A C G T A G G T A C G T A C C T A C G T A C C A A C G T A G G A A C G A A C G T T C C A A C C T A G C T A C C A A G G A T C C A A C C T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T T G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T T G C T A G C A A C G T A G C A A G G T A G C T T G C A T G C A T C C T A C G T T G G A A C G A A G C A A C C T A C G A T C G A T G C A T G C A A C C A A G C T A G C T T G C T T C G T T C C T T C C T T C G A T C C A T C C A T G G A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T T C G T A G G T T G C A A C C A A G G T A G C A T G G A T C G T A G G A T C G A A C G A T C C T T C G T A C C T A G G A A G G A T G G T A G C T T G G T T G C T A G G T T G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C T T G C A T G G T T G C T A C C T A C C T A G C T A C G A T G C T A G C A T C G A T C G A A G G A A G G A A C C T A G C T T G G T A G G A A C C A T G C A A G G T T G G T T G G T A G G A T G C T T G G A A C C A A G G T A G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G C A A C G T T G G T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G C A A G C T T C C T T C G T T G C T A G C A A C C T A C G T T C C A T C G A T G C T A G G A T G C A A G C A T G G A T C C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C C T T G G T A G C T T G C T T C C A A G C T A C C T A G C T T C C T A G C T A C G T A G G T A G G A A G G T A C C T +65 A C C T A C G T A C C T T G C T A G G A T G C T A G G T A C G A T C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G A A C G A T C G T A G C A A C G T T G C T A G G T A G G A T G C A A C G A T G C A A G C T A C C T T G C T T G C A A C C A T C C T A G C T T C C A A C C T T C G A A C G A A G C T A C C A T C G T T C C A A G G T A C C A A C G A A G G T T G C T A C G T A G C A A C G A T G C A T G C T A G C T A G G T T C C T A G C A A G G T A C G T A C C A T G C T T G C A A G G T A G C T A C C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A A G C T A C G T A G G T A G G A A G C A A G G T A C G A A C G A T C C A A C G T A G G T T C G A A G G T A C G A A G G T T C G T T C G A A G C T T G C A T G C A A C C A T G G A T C C A A G G A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A A C C T A C G T T G G A T G C A A G C A T G C A A C C A T C G T A C C T T G G T A C C T A G C T A G C A A C G T T C G T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A A C C A A G C T A G C A A C G A T G C T A G C A T C G T T G C T A C G T A G G T T C C T T G G T A C C A A G C T T C C T T C G T A G G T A C G T T G G A T G G T A C C A T G G T T C C A T C C A T C G A T G C A A G G A A G G A T C C T A C G A T C G A T C C A T C C A A G C A A C C T A C C A A G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A A C G T A C C T T C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T G C A A G C T A C C T T G G A A C G A A G C A T C C T A C G T A G C A A G C T T G G A A G C T A G G T A C C A A G C A T C G A A C C T T C G A T G G T T G C T A G G A T C C A A G G A A C G T A C C T T G C A T C C A T G G A T C G T T G G T T G C A A G G T A C C T A C G A T G G A T C G T A G G A T C G T A G G A T C C T T C G T A G C T A G G A A C G A T G C T A C C T T G G T T G C T A G G T T G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C T T G C A T G G T T G C T A C C T A C C T A G C A A G G T T G G T T C C A T C C A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T G G A A C C A A G G T A G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G C A A C G T T G G T T C G T T C C T T G G T T G C T T G C A A G C T A C C A A G C A A G C T T C C T T C G T T G C T A G C T A C C T A C C A T C G A A G G A A G C T A G G T A C C A A G G T T C G T T C C T A C C T T C C A A G C T A G C T T G C T A G G T A C C A T C C T A G G T A C C A T C C T T G C T A C C T T G C A A G C T T G G T T G C T T G C A A C C T A G C A A G G T A C C T A G C T A G C T A G C A A C G T A C C T +66 A C C T A C G T A C C T T G C T A G G A T G C T A G G T A C G A T C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G G A T C G A T G G A A C G T T G G T A G G T T C C A T G C A A G C T A G G A T G C T T C C A T C C A T C C T A C G A T G C T T G C A T C C A T C C T A G C A T C C A T G G T T C C T T G C A T G C T A G C A A G C T T C G T A G G A A G G A A C C A A G C T T G C T A C C T A C C A A C G T T G C T A G C T A G G T A G G T T G C T A G C T T C C A T G G T A C G T A G C T T G G A A C G A A G C T A C C A A C G A A G G T A G G A T G C T T G C T T G C A A C C A T C C T A C G A A C G T T G G T A C G A A C G A A G G T A C C A A G C A T C G A A C C A T G G A T G C A T C C T A C C A T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G G T A C G T T C C A T G C T T G G T A G C T T G G A A G G T A G C T T G C A A G C T A G G A A G G T T C C A T C G A A G G T T G G A T C G T A C G A T C C T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A G G A A G G A T G G A A G C A A C G A A C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T C G A T G G T T C G A T C C T T G C T A G C T T G C T A G G A A G G A A G C T T G C T T C C A T C C T T C G T T G C A A G C A T G G T A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G G T A G C T T C C A T G C A T C G T T C G A A G C A A G C A T G G T A G C A A C C A T G C T T C G A A C G T A C C T T C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T G C A A G C T A C C T T G G A A C G A A G C A T C C T A C G T A G C A A G C T T G G A A G C T A G G T A C C A A G C A T C G A A C C T T C G A T G G T T G C T A G G A T C C A A G G A A C G T A C C T T G C A T C C A T G G A T C G T T G G T T G C A A G G T A C C T A C G A T G G A T C G T A G G A T C G T A G G A T C C T T C G T A G C T A G G A A C G A T G C T A C C T T G G T T G C T A G G T T G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C T T G C A T G G T T G C T A C C T A C C T A G C A A G G T T G G T T C C A T C C A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T G G A A C C A A G G T A G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G C A A C G T T G G T T C G T T C C T T G G T T G C T T G C A A G C T A C C A A G C A A G C T T C C T T C G T T G C T A C C A A C C T A C G T T C C A T C G A T G C T A G G A T G C T A G G A T G G T T C G A A C G A A C C A T G C T A C C T T G C T A G G A A G C A T C C T T G C T A C G A A G C T T G G T T G C T T C C T A G G T T G G T T C C A A G C A A C C T T G C T T G G A A G C A A C G T T G C A A G C A A C C T A G C A +67 A G C T T G G A T G C T T C C T A C C T T G G A A G G T T G G T A C C A A G G T T G C T T G C T A C G T T C G A T C C A A C C A T G C T A C C T T C C T A C C A T G G A T C C A T C C A T G G A A C G T T G C T A G C A T C G T A C C T A G G A A C C A T G C T T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C G A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G C T A G G T T G G T T G C T T G G T A G G T A G C A T G C T T C C A A G G A A G G T A C C A A C G A T G C T A C C T A G G A A G C T T G C A A C C A T G C A A C C A A C G T A C G A A G C T T C G A A G C T A G G A A C G T A G G A A C G T A C G A T C C A A C C T A C C T T C G A A G G A T C C A T C G A T G G T T C C T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G C T T C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T G C T A C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G C A A G C T T C C A T C C A A C G A A C G A T C G A T G G A T G G A A C C A A C C T T G G T A C G A T G C A A C C T A C C A A G G T A G C T A G G T T G C T T G C T A C C T A G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A C G A A C C A T G C T T C G A A C C T A G G A A G G T T G C A T C G A A C C T A G G A T C G T T G C T T G C A T C C T A G G A A G C T T G G A A C C A T C C T A C C T A C G A T G G A T C C T A G G A T G C T A C G A T C C T T C G T A G C T T C G T A G C T T G C T A G C T T G G A T G C A A G G T A G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C T T G C A T G G T T G C T T C C T A C G T A G C T A G G T T C G T A C C A T C C T T C G A T G C T T G C T A G C A A G C T T C C T T G G A A C G A A C G T T G G T T G G A T G G T A G G A T G C T A C C T T C G T A G G A A C G T T C G T T C C T A G C A T C C T A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A G G A T C C A T C G T T G C A A C C T A C C T A G G A T C C A T C C A T G C T T G G A T G C T A C C A A G G A T C G T A C G A T G C T T C C A A C G A T G C T T G G A A C C A T C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C T T G G T T G C T A G C T A C G T A G C A A G C A A C G T T C C T A G C T A G C A A G C T A C G T +68 A G G T A C G T A C G T A G C A T G G A T G C T A G G T A G C T A C C T A G G T T G C T T C C T A C G A T C G A A G G A A C C A T G C A T C C A T G C A A C C T A G C A A G C A T C C A T G G T T C C T T G C T A C C T T G C T A C C A A G G A A G C T T G G A A C G T T G C A A C C T T C G A A G G T A G G T T C C A T C C T A G C T T C C A T G C A T C G A T G G T A G C T A G C T A G G T T G G T A G C T T G C A A G C A A G C T T G C A A G C T A G C T A G C T T G C T A G G T T G G T A G G T T G G T A G G T T G G A T G C T A C C T A G C T T G G T A C G A A G G T A C C A A C G A A G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C C A A G G T A G C A A C C T A G G A A C G A A C G T T C C A A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A A C C A A C G T T G C A T G C A A C C T A G C A T C G A A G G T A C G A T G G A A G C T T G G A A G G T T C C T A G G A A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G G A T G G A T C C T A G C A A G C A A G G T A C C T A G C A T G C A T C C T A C C T A G G A A G C A T C G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A C C T T G C T T C C T T C C T T C C A T G G T T G G A A G C A A G C A T C G A A G C A T C G A T G C A A C C A A C G T T G C T T G G A A G G T A G C T A G G A A C G A T C G A T G G A T G G A T G G T T C C T T G G A A G C A A C C A A C C T A G G T T C C T A G C T T C C T T G C A T G C A A G C T A C C A T C G A T G C A A G C T T G C A T G G A A G G T T C G T A G C A A C C A A G C T T C G A A G G A A C C T A C C A T G C A T C G A T C C T A C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A G C A A G C T T C C T A C G A T G G A T C G T A G G A T C G T T G G A A C G A T C G T A G C T A C G A A G C T T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T G G T A C C A A G C T A C G T T G C A T C G T A C G T A C C A T C C T T C G A T G C T T G C T A G C A A G C T T C C T T G G A A C G A A C G T T G G T T G G A T G G A T G C A A C G A A G G T T G G T A C G A T G G A T C C T T C C A A G C T T C C A T C C T A G C A T G G A T G C A A G C T T C C T A G C T A G G T T C G T A G C T T C G T T C G T A G C A T G C A A G G A A C C A A C G A T C C T T G C A A C G T A C C A A G C A T G G A T C G A A G C T A G C T T C C A A G C A T G G A A G C T A G G T A G G A T G C T A C C T T G C T T C C A A G C T A C C T A G C T A C C A T C C T T C C T T C G T T C C T T G G T T G C T T G C T A C C A A C G T A G C A T G C A A G C A T C C T A G C T A G G A A G C T A G C T +69 T G G A A C G T A C C T T C G T A C C T A G G A T G C T T G G T A C G A A G G T A G G A T G C T A C G T T G G A T G G T T G G T A G C A T C C T T G C A A C C T T G C T A G C A A G C A T C G T T G G T A G G T A G C A T C G T A C C A A C G A A G C A T G G A A C G A T G C A A G C T A C C A A G C T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C A A G G T T G C A A G C T A G C A A G C T T G C T A G C T A G C T A G G T T G G T A G G T A G G A A G C T A C C T A G C T A C G A A C G A A G G T T C C A A C C A T G G T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G T A C G A T G C T T C G A A G G T A G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G T T C C A T C G T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A C G T A G C A T G C A A C G T A G G A A C G T A G G T T C G A A G G T T G G A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T T G G T A G G A A G G A T G G A T G C A A C C T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T T C G T A G G T A C G T A G C T T G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C A A G C A T C G A T G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T A G G A T C C T A C C T A C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G G T A C G A T G G T A G G T A C G T A G C A A C C T A C G T T C C A A G G T A C C T T G C T T G C A T C C T A C G T A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G A A G C T A G G T A C C T A G C A A G C T A C C T A C C A T C G T A G G T A G C A A C G A T C C T T C G A A G C A T C G A A G C T T G C T A G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G T A C C A A C G A A G G T T G C A A G G A A G G A T C G A T G G A A C C A A G G T A G G T A C C T T C G T A C G T T C C T A C C T A G C T T C G T T G G A A G C T A C G A A G G T T C G T T G G T T G C A A G G T A G C A A G C A T G C A A G G A A C C T A C C A T C G T T G C A A C C T A C C T A C G A T C C A T C C A T G C A T C G A T G G T A G C A T G C T A G C T A C G A T G C T T C C A A C G T T G C T T G G A A G C A T C C T T G C T A C G T A C C A T G C T A C C T T G C A A G C T T G C T T C C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +70 A C C T A G G T A C G T A G C T A G C T T G C T A G C T A G C T A C G A A G G T T G C T T C C T T G G T T C G A T G C A A G G T A G C A T C C A A G C T A C C T A G C T A G C T T G C A T G G A T C C T T G C A A G C A T C G T A G C T A G G A T G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G G A T G G A A G C T T C G T A G C T T G C A A G C T A G C T T G C T A C C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T A C C A T G G T A G G T A G G A T G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A A G G T T G C T T G C A A G C A T G C A A C C A A C G T A C G A A G C T T G G T A G G T A G C A A G C T A G G T A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C T T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T T G C T A G C T A C C T A G G A A G G A A C C T T G C T T C C T T C C T A C G A T G G T T G C A T G C T A C C A T G G A T C G A T C C A T C C A A G C A A G C T T G C A T G G T T C C A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A C G T T C G A T G G T A C G T A C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C G T A G G A T C G A T G G A T C C T T C C A T G C A A G G A A G G A T G C T A C C A A C G T A C C T A C C A T G C T A G G A A C G T T G G A T G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T G G T T C G A T G G T T C G A T G G A A G C T A G C T A G C T T C C T T G G A A C G A T G C A A G G T T G G T T G C T T G C A T G C T A G G A T C G T A G C A A C C A T C C T T C C T A C G T T C C A A G C T A G G T T G C T A G C T T C G T T C G A A G G A A G C T T C C T A G G T T G C A T C G T A G C A T G C A T G G A A G C T T C C A T C G T T G C T A C G A A C C T A C C A T C G A T C G A A G C A T C G A T G C A A G C A T G G A T C G A A C G A T G C T T C C A A C G T T G C T T G C A A C C A T C C T T G C T A C G A A G C T A G C T T C C T T C C A A G G T T G C T T C C A A G G A T C G A T G C T A G C T A G C T A C G T A G G T A G G A A G G T A C C T +71 T G C T A C G T A C G T T G C T A C C T T G C T A G G T T G G T T C C T A C G A T C C T T G C T T G C A T C G T A C C T A G G T A G C A T G C T T G C T A G C A T G G T A G C A T G C T T G G A T C C T T G C T A C C T T G C T A C C A A G G A A G C T T G C A A C G T T G C A A C C T T C G A T G G T T G G A T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C A A G C T T C G T A G C T T G C A A G C T A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T T G G T T G G T A G G T A G G A A G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A G C T T C G T A G G T T G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G C T T C C T T G G A T C C T A G G T A G C A T G G A A G G T A C G T T G C A A C C T A G G T A G C T T C C A T G C A T C C T A G C A T C C T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G C T A C C T A G C A T G C A T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T T C C T T C C T A C G A T G G T T G G A T G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A C C T T G G T T C C A T C G A A C G T A C G A T C C A A G C A T G G A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A C C T A C G T T C C A A G C T A C C A T G G A T C G A A G C T T C G A A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G G T T C G A T G G T T C G A T G G A A G G A A C G T A G C A A C C T T G G A A C C A A G C A A G G T T C G T T G G T A G G A T G C T T G G A T C G A A G G T A C G T A C C T T G C A A C G A T C C T A C C T A G C T T C C T T G G T A G C T A C G A A G G A A G C T T C C T A G G T T G C A T C G T A G C T A G G A A G C A A G C T T C C A T C G T T C C T A C C T A C C T T C C T A C C A T C C A T G C T T G G A T G C T A G C A T G G T A G C T A G G T A G G A T G C T A C C T T G C T T C C A A G G T A C C T A G C T A C G T A C C A T G C T A C G T T G C A A G G T T G C T T C C T A G C A A C G T A G C A A G C A A C G T T C C T A G C A T G C A A C C A A C G T +72 A C C T A G G T T C G T A G C T A C C T T G C A A G G A A G G T A C G A A G G T T G C T T G C T T G G T T C G A T C G T T G G T A G C T A C C T T G G T A C C T T G G T A G C T T C C A T C G T T G G T T G C T A C C A T G C T A C C T A C G T A G G A T C C T T C C A T G C A A C C T T C G A A G G T T G C A T C C A T C C T A G C A T C C A A C C T T C C T T C G A A G C T A C G A A G C T T C G T T G C T T G C A A G C A A G C T T G C T A C C T A G C A A C G T A C C A A G C A A C G T A G G T T G C T A G C T A G G A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C G A A G G T A G G T A C G A A C C T T G C A A C C A A G C T A C C A T C G T A C G A T G C T T C G A A C G T A G C A A C G T T C G A A G G T A C G T T G C A T C G T T G G A A G G A A G G T A G C A A G G T T G G T T C G A A G C T A G C A T G G T A G C T T C G A A C C A T G G A A C C A A G C A T G G T A G C A A G C T A G C T A G C T A C G T A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A C G T A C C T T G G T A C C T A G C A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G G A T G C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A G G T A C C T T C G T T G C A T G G A T C C T T G C T A G C T A C C T A G G A A G G A A C C T T G C T A C C A T C C T A C G T T G G T A G C A T G G A A C C A T G G A A G C T T C C A T C C A A G C A A G C T T G C A A G G T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A C G T T C G A T G G T A C C T A C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C G A T G G T A G G T A G G T A C C A A G C T A C G A A G C T A G G T A C C T T G C T T G C A T C C T A C G T A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C G A A C C A T G G A A G C T A G G T A C C T A G C A A G C T A C C T A C C A T C G T A G G T A G C A T G G A T C C T T C C A T G C A A C G A A G C T T G C T A C C A A C G T A C C T A C C A T G C T A G G A A C G T T G G A T G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C G T T C C A T C C A T C G A T G G A A G C T A G C T A G C T T C C T T G G T A C C A A C G A A G G T T G C A T G C T T G C A T G G A T G G A T G G T A G C A A C C A T C C T T C C T A C G T T G C A A G C T A G G T T C G T T G C T T C G T T C C T A G C T T C G A A C C T T G G T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C G T A G C T A C G A A C C T A C G A T C G A T C G A A G C A T C G A T G C A A G C A T G G A T C G A A C G A T G C T T C C A A C G A T G C T T G G A A C C A T C C T T G C T A C G A A G C A T G C T A C C T T G C A A G C T T G C T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +73 A G C T T G G A T G C T T C C T A C C T T G G A T G G T A G G T A G C A A G G T T G C T T G C A A C G A T C G A T G C A T G G T A G C A T C C T T C C T T G C A T G G T A G C A T C G A T G G A A G G A T G G T A G C A A C G T T C C T A G G T A G C A T G G A A C G T T G C A A C C T A C G T A G G T T G G T T C C A A C C T A G C A T C C A T C C T T C C A T G G A T G C T A C G T A G C T T G G T A C C T A G C A A G C A A G G T T G C A A G C T A G G A A C G A T G G A A G G T A G C T A G G T T G G T T G G T T G G T A G G T A G G A T G C T T C C A A C G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C C T A C G A T G C A A C G T A G G A T C G T A C G A T G C A A G C A A G C T T C G T A C G T A G C A A C C T T G G T T G G A A G C T T G C T T G G T T G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T T G G T T C C A A G C T T C G A T C C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A A C G T T G C A T G G A T C C T A G C T A G C T T G C T A G G A A G C T A C C T T G C A T G C A T C C T T G G T T G G T T G G T T G C A A G C A T C G A T C G A T G C A T G C A A C C T A G C T T C C T T G C T T C C A T C C A A C C T A C G A T C G A A G C T T G C A T C C A A C C T T G C T A C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G C T A C C T A C G A A G C A A G G T T G C T T G G A A C G A T G G T A G G T A C G T A G C A A C C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A G G T T G G T A C C T A G G T T C C T A C G A A C G A T G G T A G C A T C G T T G G A A C G A T C G A T C C T A C G A A G C T T G C T A G C A T G G T A C C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G T A C G T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G C T T G C A T G C A T G G A T C G T A G G A A C C A T C C T T C C T A C G T T C C A A G C T A G G T T G G A T G C T T C G T T C G T T G C T A C G A A C C T A G G T T G C T T C G A A G C A T G C A A G G A T G C T T C C A T C G T T G C A A C G A A C C T A C G T T C C A T C G A T G C T A G G A T G C A A C G T T C G A T C G T A C G A A G G A T C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C G T T C C T T G G T T G G T T G C T A G C T A C G T A G C A T G C A A G C A T C C A A G C T A C C A A G G T A C C T +74 A G G T A C G T A C G T A G C T A C G A A G C T T G G T A C G T A C C A A C C A T C C T T G C A T G C T T G G A A G G T A G G T A G C A T G G T T C C T A C C A A G G A T C C A T G C A T G G T T C C T T G G T T C C T T G C T A C C A A C G T A C C A T G C A A C G T T G C A A C C T T C C T A G G T T G C T A C C A T G C T A G C A A G G A T C C A T C G A A C G A A G C T A C C A T C G T T C C T A G C A A C C A A C G A T G G T A G C T A C G T A G C A A C G T A C C T A G C T A G C T A C C T T G G T A G C T A G G A T G G T A C C A T G C T A C G A A C G A A G G T A C G A A C G A A G C T A C G A A G C T T G C T T G C T T C C A T C C T A C C A A G G A A C G T A C G T A C C T A C G A T G G A A C C T A G G A T C G A A C G A T C C A A C G T A G G T A C C A A G G A A G C A A G G T T G G A T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T T G C A T C C A A G G T A G C T T C C A A G G T A C G T A G G T A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G T T C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T C C T A C G T A G G A A C C T T G G A T G C T T C G A T G C T A C G T A G G T A C C T T C G T T C C A T G C A T C C A T G C T T C C T T C C A T G C A A G C A T G G T A C C A T G G A T G G T T C C A T C C A A G G A A C C T A G C T T G G T T C C A T C G T T C G A A C G T A G C T A G C T T G C T A G G T T C C T T G G T T C G T A C C A A C C T T C C T A G G T A G G T A G G T T G C T T G C T A C G A T G C T T C C A A G C T T G G T T G G A T C C A T C G A T C C T T C G T A G C A A G C T A C G A A G G A A G C T A C G A A G C T T G C A A C C T T C G A A G G T T G G A A G G A T C C T T C C A A C G T T C C A T G C T T C C A T G G T A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C A T G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C C T T G G A A G G A A C C T A G C T T C G T A G G T A C C A A C C T T G G T T G G A T G G A A G G A T G G A A C G T T G G A A G G T A C C A T C C T T C C T A C G T T C C A A G C T A G G T T C G T T G C A T G C A A G G T A C C A A G C T T C C T A G C T A G G A T G C A A G C A T G C A A G G A T C C T T C C A T C G A A C C A A C C T A C C T A C G A T C G A T C G A T G C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A G C T T C C T T G G A A C C A T G C T T C C T T C C A T C G T T C C T A C G T T G C A A G C T T G C A T G C T A G C A T C G T A G C T A C G A A G G A T C C T A G G T A G G T A G C A A C G T +75 T G C A A C G T A C C T A G G A T G G T A C G A T G C T A G C T T C C T T C G A A G G A T G C A A C G A T G G A T C C T A G G T A G C A A C C T T C G T A C C T A G C T A G C A T C C A T G G T A G G T T G G A A G C A A G G T A G C T A G G T A C C A T C C T T C G A T G C A A C C T T C G T A G G T T G C T T G C A T C C T A G C T T C C A T C C A T C C A T G G A T G C T A G C A A G C T T C G T A C C A A G C A A G G A T G G A A G G A A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G T T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C C A A C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C T A C C T A C G A A G C A A G G T T C C T A G C A A G G T T G G A A C G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G C A T G C T T C C A A G C T A C C A T G C T A C C A T C C T T C G T T G G T A C C A T G G A A C C A T C C A A G G A A G C A T C G A A G C T A C C T T G G T A G C T T C C A T C G A T C G T A C C A T C G A A G C A T G G A A G G T A C C T T C C T A C G A A C G T A G C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T A C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G G A T C G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C G T A G G A T G C T A C G A T C G A T C G T A C C T A C G T A G C T T G C T A G G A A G G T A C C T A G G T T G G A T G G T A C G A A C G T A G C T A G C T A G C T T C C T A G C T T C G T A C C A A G C T A C G T A G C A A G G T T G C T A G C A T C C A T G C T A G C T T G G A A C C A T G C A A C G T A G C A A C G A T G C A A G C A A G C A A G G A A G G A T C G A A C C T T C G T A G C A A C C T T C C T T G C A A G G T A C G A T G C T A G C A T G G A T G C T T C G T T C C T A C C T T G C T T C C T A G G A A G C T A G G T A G C T A C C A A G G A T G C T T C C A T C G T T G C A A C C A A C G T A C G A T C C A T C G A T C C T T G G T T C G A A G G A T G G A T C C T A C G A T G C T T G C T A C G A T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T T G G T T G C A A G C T T G G T T G C T T G C A A C C T A G G A A G C T A G C A A C C T A G C T A G C A A G C T A C G T +76 A C C T A G G T A C G T T G C T A G C T T C C T A G G T T G G T A G C A A G G T T C C T T G C A A G G A A C G A T C C A A C C T A G C T A C C T T G C A A C C T T G G A T C C A T C C A T G G A A C C T T G C T A C C A T G C T A C C A A C G A A G C T T C C T T C G A T G C A A G C A A C G A A G G T T G C T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G C A A G C T A G C T T G G T A C C T T G C A A G C A A G G A T G C A A G C T A G C A A C C T A C C T A G C T A G C T A G C T T C G T A C G T T G G A A G G T A G G A T G C T T G G A A C G T A G C T A C C A A C G A A G G T A G G T T G C T A C C A T G C T A C C A T G C A A C C A A G G T A C G A T G C T A C G T A G G T A G G A A G C T A G G A A C G T A C G A T G C A A C C T A G C T A C G T T C G A A G C A A G G T T G G T T C G A A G C T A G C A T G G T A G C T T C G A A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C A A G G T A C C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G A A G C A T C G A A G C A A G C T T G C A T G C T T C G A A G G A T C G T A C C A T C G A A G C A T G G A A G G T A C C T T G C T A C G A A G G A A G G T T C G A A G G T A C C T T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C A T G G A T C G A T G G T A G G T A G G T A G C A A G C T A C G A A G G A T C G T A C C A T G C T T C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A T G G T T G C A T G G T A C G T A C C A T G G T A C C T A G G T T C C A A C G A T G C T A G C T A G C T A C C T T G C A A G C A A C C A A G C T A C C T T G C A T C G T T C C T T C C A T C C T T C G T T C C A A G G A A C G A A G C A A C C T T G G A A C C A T G C A A G C A A G G A T G G T A G G A T G C A A G G T T G G A A G G T A C C T T C C T T G C A A C G T A G C T A G C T A G G T T G G T T G C A T G C T A C C T A G C T A G G T T C G T A C C T A G C T T G G T A G C A T G C A A C G A A C G A A C G A T C G T T G G T A C G A A C C T A C G T A C C A T C C A T C C T T G G A T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G T T G C T A G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +77 A C C A A G G T A C G T T G C T A G C T A G C T A G G T A C G T A C G A A C G A T G C T T G C T T G G A A G G A A C C T A G G T A G C A A C C T T G C T A G C T T G G T T G C A T G G A A C G T A G C T T C C A A G C A T C G A A C C T A G G T A G C A T G C A T C G A T G C A A C C T T C G A T G G T T G C T A G C A T C C T A G C A T C C A A C C T T C C T T G G T A G C A A G C T A G G A T C G T A G C T T G C A A G C A A G G A T G C T A C C T A C C A A C G A T G G A A G C T A G G A A C G T T G G T A G G T A G G A A G G T A G C A T G C T T G G A A C G T A G C T A C C A A C G A A G G T T G G A T G C A T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A C G A A G G T A G G T A C G A T C C A T C G T T G G A A G G A A G G T A G C A A G G T T G G A T C G T T G C T T G C A T G G T T G C T T C C T A G C A T C G A A C G T T C C A T G C A T C G A A C C T A C C T A G G A A G G A A C G A T G C A T G G T A G C A T G C A A C G T T C C A T G C T T G G T A G C T T G G A A G G T A C C T A C C A A C C T A G G T A G C T T G C T T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C T A G G A A G C T T C G A A G G A A G G T A G G T T C C T A G C A A G G T T G C T T G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G G A A C C T A C C A A G G T T C G A A G C T A C C T T C G T A G G A A G C A T C G A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C A T C C T A C C A T G C T A G G T A G C A A G G A T G C A T C C A T G G A T C G A A G C T T C C T A C G T A C C A T C C T A C G A A C G A A G C T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T T G G T A C C A A G C T T C G T A G C A T G G A T C G T A G G A T C G T T C G A A C C T T C C T A G C T A C G A A C G A T G G T T G G T T G G T T G C T A G G T A G C T T G G T A C G T T C G A A C C T A G C A A G G A A C C T T G G A T C G A A C G T A C C T A C G T A G C T T C G T A C C T T C C A T C C T T C G T A G G A A G C T A G C A A G G T T G G T A G C A T C C A A G C A A G G T T G G A T G C T T G C A A C C A T C G A T C G T A G G A T G G T T C C T T C G T A C G T A C G T A G C A T G C T T C C T T G G T A G C T A C C T A G C T A G G T T C G T A G C T A G C T T C G T A G C T A C C A A G G A A G C T T C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A T C C T A G C A T G C A A C C A T G G T A G C T A C G A A G G A T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G C T A C C T A G C A A G C T A G G A A C C T A G G T T G C A A C C A A C G T +78 A G C A A C G T A C C T T C C T A C C T T C G A A G G T A C G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A G C T T G G T A G C A T G C T T G G T T G G T T G G T A C C A A G G T A C C A A G G A A G C A T C C T T C G A T G C A A G C T T C G T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G C T T C C A T C G A A C C T A G G T A G C T A G C A A G C T T G C T A C C T A C C A A C G T T C C A A G C T A G G T A G G T T G G T A G C T T C C A T G C T A G G A T G C T T G G A A C G A A G G T T C G A A C G A T G C T A C G A A G C T T G C T T G C T T C C A T C C T A C C A A G G A A C G A A C G T A C C T A C G A T G G A A C G T A G G A T C G T A C G A T G C A A G C A A G C T T C C A A G G A A G C A A G G T T G G A T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T A G G A A C C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C A A G G T A G C A T C C A A G G T A C G A T G G A A C C T T G G A A C G T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T A C C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A C G T A G G T T C C A T G C A A G C T A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G A A G C A T G C A A C C T A C C T A G C T T G G T T C G A T C G A A C C T A C G T A G C T T G G A T G G T A G C A T C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T A G C A T G G A T C G A T G C T A G C T A G G T T G C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T G G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A T G G A T C C T T C G A A G C T A G G A A C G A T G G T A G C A A C G A T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C A A G C T T C C T T G C A T G C A T C C A A C C A A C G T T G C A T C G A A C G T A G C A T C G T T C C T T G G A A G G A A C C T A G C T T C G T A G G T A C C A A C C T T G G T T G G A T G G A A G G A T G C A A C G T T G G T A C G T A C C T T C C T T G C A A G G T A C G T A G C A T C G T T G C T A G C A A C G T A C G A T G C T A G G T T C G T A C C T A G C T T G G T A G C T A G G A A G C T A G C T T C C T T C G T T C C T A C C T A C G T A C C A T C G A T C G A T G C A T C G A T C G T A G G A T G G T T C G A A C G A A G G T T G C T A C G A T G C T T G G A A G C T A C C T A G G T A C C A A C C T T G C T A C C T T C C T A G G T T G C T T C G T T G C A T C G T A G C T A G C T A G C A A G C A A G C T A G C A A C C T A G C T +79 T G C A A C G T A C C T A G G A T G G A A C G A A G C T A C C A A C C A A G G T T G C T T G C T T G G T T C G A T C C T A G G T A C C T A C C T T C C T A C C T A G C T A G C A A G C T T C G T A G G A T C G T A G C A A G G T A G C T A G G A A C C A T G C T T C G A T G C A A G C T T C C T A G G T T G C T T G C A T C C T A G C A T C C A T C C T T G C T T G G A A G C T A C C A A G C T T C G T A C G T A G C T A G C T A G G T A G C T A G C T A G C A A C G T A C C T A G C A A C G A A G G T T G C T A G C T A G G A T G G T A C C A T G C T T G G A T G G T A G G T A C C A A C G A T G G T A G G A T G G T T G G T T G C A A C C A T G C T A C G A A C G T A G C T A G C T T C C T A C G T A C G T A C G T T G G T A C G A A C G A T C C A A C G T T G C T T C G T A C G T A G G A A C G T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G C T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A G C A A G G T A C C T T G C A A C G T A G G A A G G A A G G T T G G T A G G T A C C A T C G T A C G A T G G T A C C T T G C T T C G T T G C A A C G T T G G A T C C T A C C A T C C T T G G T A C C A A G C T T C C A A G C A A C C A A G C A A G C T A G C T A G G T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G G A T G G A T G C T A G C T A G G T A C G T T G C A A G C T A G C A T G C T A C C T T C C T A C G T T G G T A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G G A A C C T A C C A A G G T T C G A A G C T T C G A A C C T A G C A A G C T T G C A A G C A A G C T T G C T A C G A A C C T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A G G T A C G A A C C A A C C T A G G A A G C T A C G T A C C A T G C A T C G A T C C T A C G A A G G A A G C T A C G A A C C A A G G A T G C T T C C T T G C A T C C A T C G T A C G T A G G T T G C A A G C T A C C T A G G A T G G T A C G T A G G A T C G T T C G A A C C T T C C T T G C T T C G T T G G T T G C T T G G T T G G T T G C A A G G T T G C T A G G T A C G T T C G A A G C T A G C T T G C T A C C T T G C A T G G T A C C A A G C T A C G T T G C A T G G A A G G T T G C A T C C T T C G A T G C T T G C T A G C A A G C T T C C T T G G A A C C A T G C A A G G T T G G A T G G T A G G A T C C T T G G T T G G T A G G A T G G T T C C T T C G T A C G T A G C T A G C T T G G T T C G T T G G A A G C T A C C T A G C T A G G T T C G T A G G T A G C T T C G T A G C A T G C A T C C A A C C T A C C T T C G T A G C T A C C A T C G T A G G A T C G A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A A C G T A G C A A G C A A C G T T C C T A G C T A G C A A C G T A C C T +80 A G G A A C G T A C C T T G C T A C C T T C G A A C C A A G G A T C C A A G G A T G C T T G C T T G G A A C G A T G C T A G G T A G C T A C C T T C C T A C C T T G G A T C C A T C C T T G G T A G G T T G G T A G C A T C C T A C C A A G G T A C G A T G C T T C G T T G C T A G C T T G C A A G C T T G C T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C T A G C T T C C A A G C A A G C A A G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G C T T G G T A C C T T G G T A G G T A G G T A G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T G C A A C C A A G G T A C G A A G C T T C G T A G G T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G T A G C A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C G A T G G T A C G T A G C T T C C T A G G T A G C T T G G A A G G T A C G A T G G A A G C T T G G T T G C T A G C A A G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G G T A G G A T C C A A C C A A C G A A C C A A G G T A G C T T G C A T C G T T C C T A C C T A G G A A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G C T T G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A T C G A A C C T T C G T A G G A A G C A T C G A A G C A A G C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G A T C G A A G G T A C C T A C G A A C C A T G C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T T C G T A G G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A A C G T A C C A T C C A T G C T T C G A A C C T T C C T A G G T A G C T A G C T A C C A A G C A T G G T T G C A A C C A A C G T T G C A A G G A A G G T A G C A T C C T T C G T A G C A A C C T A G C A A G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A C C T T G G T A C G A A C G T A C C T T C C T A G C A T G C T A G C T A G C A T G G A T G C A T G C T A C C T A G C T A G G T T C G T T C C T A G C T T G G T A G C T A G G A A G C A A G C T T C C A T C G T T G C A A C C A A C G T A C G A T C C A T C G A T C C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +81 A C G T A C G T A C G T A G C A A G G T T C C T A G G T A C C T A C G A A G G T T G C T T G C T T G G A A C G A A C C T A G G T A G C A T G C T T C C T T G C A T G G A T C C A T C C A T G G A A C G T T G C T A G C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C T T C C A T G C A T C C A A G G A T G C T A C G A A G G T T G G T A G C T T G C A A G C T A G G A T G C T A C C T A G G A A G C T A C C T T G C T T G C T A C G T T G G T A G G T T G G T A G G T A G G A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C A T G G T T G C A A G C A T G G T A C C T A C G T T G C T A G C T T C G A A C C T A G G A A G C T A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C A A C C T T G G T A G C A A G C A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T A G G A T C C A A C C A A C G A A C C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A C C T T G G T T G C A T G G A T C C T A G C T A G C T T G C T T G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A C C A T G G T A C C A T G C A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C G T T G C A A C C T A C C T A G C A A G C T T G G A A G G T A C C T T G C T A C G A A C G T T C C T A C C T T G G T A C C A A G C T T C C A T G C A A C C T T G C A T C G A T G C T T G C T T G C A A C G A A G C T A G G T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T A C G T T G C T A G G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A C C T T C G T A G C A T C G A T C G T T C G T T G C A A G G A A C C T T C C T A C C T T C G A A C G T T G C T A G C A A C G T A C C A T G G T A G C T T G G T A C G T T C G A A G C T A C C A T G G T T C C A T G C A T G G T T G C A A C C T A C G T T G C A T C G T T C C T T C C T T C C A T C G T T G G A A C C T A G C T A G C A A C C T T G G A T C G T T G C A A G G T T G G T T C G T A G G A T G C T T G G A T C G A T C G A A C C A T C G T T C C T A C G T T G G A A G C T A G G T T G G A T G C T T G C T A C C T A G C T A G G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C T T C G T T G C T A C C A A C C T A C C T T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C G A A C G A T G C T T C C A A C C T T G C T A G G A A G C A A C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +82 A C G T A G G T A C G T T G C T A G C T T C G A A G G T T G G T A C C A A G G A T C C T T G C T A C G T T C G A T C C T A C C A T G C T A C C T T G C T A C C T T G G T A G C T T G C T T G G T T C C T T G C A A G C A T G G T A C C A A C G A T G G A T G G A T C C T T G G A A C C A A C C A T G G T T G C T T G C A T C C T A G C T T C C A T G C A T C C T T G G T T G G A T G G A T C G T T C G T A G C T T G C A A G C A A G G T A G C T A G C T A C C A A G G T T C C T T G C T T G C T A G G T T G G T A C C T T G G T A G G T A C C A T G C T T C C A A G G T A G G T A C C A A C C A A G G T A G G T T G C T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C A T G G A A C C A A G C A T G G T A G C A A G C T A G C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T G C T T C C T T G G T A G C T T G G A A G G T A G C A T G G A A G C T A G G A A G G T T G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T A G C T T G G A T C C T A G C T A G C A A C G T A G G A A G G T A G C T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A A C G T A G C A A G C T T G C A A G C A A G C T T G C T A C G A A C C T T C C T A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A C C T A C G A A G C T A G G T A C C A A C C T T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A C C T A G C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T C C T A G G A A C C A T G C A A G C A T G C A T G G T A G G A A G G A T C G T T G G A T C G A T C G T T C C T T G C A A C G T T G C T A G C A A G G T T C G T T C C A A G C T A G G A A G C T A G C T T G G T A G G T A C C A T G G A A C C T A G G A A G C A A C C T T C C A T C G A A G C T A C G A A C C T A C G A T G C A T C C A A G C A T C G T T G C A A C G A A G G A T C G A A C G A A G G A T G C T A G C T T G C T T G C A A C C A A C G A T C C A A C C A A G C T T G G A T G G T T G C A A G G T T G C T T C C T A G C T T C C T T G C T A C C A A G C T A C C T A G G T A G G T A G C A A C G T +83 A G C T T G G A T G C T T C C T A C C T T G G T A G G T T G C T A C C T A G G T T G C T T G C T A G G T T C G A T G G T A G G T A G C A T G C T T C C T A G C A A G C T A C C A T G C T T G G T T C G T T G C T A C C A A C C T A G G T A G G T A C C A A G C T T C G A T G C A A G G T T C C T A C C T T G C T A C C A T C C A A G C A A G G A A C C A T C C T T G G A A G C T A C C A T C G T T C G T A G C A A C G A A G C A A G G T A C C T A G C T A G C A A C G T T G C A A G C T A G G T A G G T T C C T A G C T T C C A T G G T A C G A T G C T T C C A A G G T A G G T T C C A A C G A A G C T A G G A T G G T T G C T T G C A A C C A T C C T A C G A A C G T T G G T A C G T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C G T T C C T T C G A A G G T T C C A T C G T T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T C G T A C C A T G C A A C C T T C C A T G C T T G G A T C C T T G G T A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C C T T G G T A C C A A G C A T G G A T G G A T C C T A G G A A G G T A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G G T T C G A T C C T A G C T A G G T A C C T T G G A A G G T A C C T A G C A T G C A T C G T T G G A A G G T A G G A A G C T A G C A T C G A A G C T T G C A T C C A A C C A A C C T T C C T T G G T T C C A T C C T A G G T T C G A T C G A T C C A A G C A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C C T A C G T T C G A A G C T A C C A T G C A T C G A T C C T T C G A T G C T T G C A T C G A A C C A A G G A A C G T A G C T A G C A T C C A T G G T A C G T T C C T A G C A A C C T A C C T A C C T A C G A T C C T A G G A T G C T T G G A A C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G G T T C C T T G G A A C C A A G C A A G G T T G G A T G G T T G C A A G G A A G C T T C G T A G G A A C C A T C G T T C C T A C G T A G C T A G C A A G C A T G C T T G C T T G C A A C G A A G G T T C G T T G G A A G C T A G G A T G C A A G C T T G G A A G G A A C C T T C C T T C G T T G C T T C C A A C G T A C G A T C G A T C G A A G G T A G G T T C C A A G C A T G C T T C C T T C G T A G C A A C C T A G C A T G C T T G G A A G C A A C C T T G C T A C C A A C C T T G C T T C C T T C C A A G G T T C C T T C C A A G C A A C G T A G C A T G C A A G C A T G C T T G G T A G G A A G C T A C G T +84 A G C T A G G T A C G T T G C T A C C T T G C T A G C A A G C T A C G A A G G T T G C T T G C T A G G T T G G A T G G T T G G T T G C T A C C T A G G A A C C T T G C T A G C A A C G A A G G A T C C T T G C T T C C A T C C A T C G T A C G A A C C A T G C A A C G T T G C A A C C T T C G T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C G A T C G A A G C T T G C T T C C T T G G T A G C T T G C A A G C A A G G A T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A G G A A G C T T G C A A C C A T C C A A G G A A C G A T C G T A C G T A C G T A G G A T G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T T G C A T C C T A G C A T C C T T G G T A C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G G A T G C A A G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C A T G G A T G C A A C C A A G C T A G G T T C G A T G C T A G G A T C G T T C C T A C C A A C G T A G G A A C C T A G G A T G G A T G C T T G C T A G G T A C G T T G C T T G C A A C C T A G C A A C C T A C C T T C C A T G C A A G C A A G C A A C C T A C G A A C G A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C G A T G C A T G G A A C C A A C C T T G C T A C G A A C C T A C C T T G G T A G G T A G G T A G G T T G C T T G C T A C G T A C G A T C G T A G C T T C C T T G C A A C G A A G C T A C C T A C G T A G C A T G C T A C C T T C C T A G G A A C C A T G C A T C G A T C C T T C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A C C T T C C T T G G A T G G T T G G T A G G T A G C A T G G A T C C T T C G T A G C T A C G T A G C T T G C T A G C T T G G A T G C A A G G T T G C T A G G T A C G A T C C T A C C T A G C T A C C T T C C T T G C A T C G A A C G A T C C T T G G T T G C A T G G T T G C T A C G A T C G T T C G T A G G A A G C T T C C A A G C T T G C A A G C A A C C A T G C A T G G T T G C A T G G T A G G A A C C T A G C T T C G T A G G A A C C T T C C T T G C A A C G T T G G A A C C A A G C A T C C T T G G T A G C T A C C T A G C T A G G T T C G T T C C T T G C T T G G T A G C A T G C A A G G A A C C T T C C A T C G T A G C T A C C T A C C T A C G T T C G A T C G A A G C T A G G A T G C A A G C A T G G A T C C T A C G T A G G A T C C T A G C A T C G T T G G A A C C A T C C T T C C A A G G A A G C T T G C T T C G T T G C A A G C T T G C T T G C T A G C A A C G T A G G T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +85 T G C A A C G T A C C T A G G A T G G T A C G A T G G T A G C T T C C T A C G A A G G A T G C A A C G A T G G A T C C T A C C T A G C A T G C T T G C T A G C A A G G T T G C T T G C A T G G T T C C T T G C A A G C A T C G T A C C A A G G A A G C T T G C A A C G T T G C A A C C T A C G A T G G T T G G T T G C A T C C T A G C A T G C A T G C T T C C A T G G A A G C T A C G A A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C G T T G C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G T A G G T T G G T T G C A A G C A T G G T A C C T A C G T T G C T A G C T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G G A T G C T A C C A T G C T T C C T T G G A T G C T A G C A T C C T T C C A A G G T A C C T T G G A A G G T A G G A A G G T T C C T A C G T A G G T T G G A T C C T T C C A A G G T A C G T T G C A T C G A A C C T A G G T A G G T T G G T A G C A T C C T T G G T A C C A A G G A T G C A A G C A T G C A A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T T G G A T C G A T C C T T G C T A G C A T G C T T G C A A C C T A C C A T G G T A G C A T C G T A G G T T G G T A G C A A G G A A C C A T G G A A G C T A G C A T C C A A G C T A G C T T G C A T G G T T C G A T C G A A C G A A C G A T C G A A G C A T G G A A G G T A C C T T G C T T C G A T C G T A C C T T C C T A G G T A C C A T G C T T C C A T G C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A G C A A G C A T G C T A C G T T C G A A G C T A C G T T G C T T C G A A C C T A C G A T G G T T G C A A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A C G A T G G A T C C T A G C A T C G T A G G A T C C T T C G T T G C T A C G T A G C T T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T A C C T A C C T T G C T A G G A A C C A T C G A T C G A A C G A T C C T T G C T A G C T T C G A A C G T A C C A T C C T T C G A A C G A A G G T A C C T A C C T T G C T T G G A A C C A T G C A A G C A T G C A A G G A A G G A A C G A T G G T T G G A A C G T A C G T T C C T T G C A T C G T T C C T A C C T A G G T T G G A T G G A A G C A A C G T T G C T T C G T T C C T A G G T T G G T A G C A A G C A T C C A A G G A A G C T A C C T T C C T T G C A A C G T T C C T A C G A T G G A T C G A A G C A T C G T T G C A A G G A T G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C A A G G T A G G T A G C T A G G T +86 A G C T A G G T A C G T T G C T A C C T T C C T A G G T A G C T A C C T A G G T T G C T T C C T T G G T T G G A T C C A A G G T A G C A T C C A T C G T A C C T A G C T A G C A A C C A T G G A A C G T T G G T A C C A T C G A T C C T A C C A T G G A T C C A A C C T T G C T T C C T T C C T A G G T T G C T A C C A T G C T A G C A A G G A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C A A C C A A G C A T C G A A G G A T C C A A C C A A C G T T C C T T G C T A G C T A G G A T G C T A G C T T C C A A G G T A C G A T G C T T G G A A G G T A G G T A C C A A C G A A G C T A G G A T G C A T C C T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C C T A C G T T G C A A C G T A G G A A C G T A C G A T C G T A C G T T G G A A G C A A G G A A G G A T C G T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T T C C A A C C A A C G T T G G A T G C A A G C T A G C A T C G A A G G T A C G A T G G A A G C T T G G A T G C T T C C A A G G A A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A T G C A T C G A T G G T T G G A T C C T A C C T A G C T A C C T A G G A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A G C A T G G T A C C A T G C A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C G A A G G A A C G A T C G T A G C A A G C A T C C T A G C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T A C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G A T G G A A G C A A C G A T C C T T C C T T G C A A G C T T G C A T C C A T G G A A C G T A G G A A C C A A G C T A C C T A C G A A C C T T C G T A G G A T C G T T G G A T C C T T C G A T G C A T G G A A C G A T G C T A G C A A C G A T C C A T G G T A G C T T G G A A C G T T G G A T G C T A G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G A A C G T A G C A T C C A T C G A A G G A A G G A A C C A A G C T A C C T T C C A T C C A T G C T T G G T T G G T T G G T A G G A A G C T A C C T T G G T A G C A A C C A T C C T A G C A T G C A T G C A A G G T A C G A T G C T A G C T A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C A T G C A A G G A T G C T T C C A T C G T T G C A A C C T A C C A A C G A T G G A T C G A T G C T T G G A T G C T A G C A T G C T A G C T A G G T A G C T T G C T A G C A T G C T A G G A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G C T T G C T A G C T A C C T A G C T A C G A A G C A T C C T A G C T A G C A A G C T A C G T +87 A G G A A C G T A C C T T C C T A C C T T C G A A G G T A G G T A C C A A G G T T G C T T G C T T G C A A C G A T G C T A C C T A C C T A C C T T C C T T G C T T G G T A G C A A G C A T G G A T C C T T G C T T C C A A G G T A G G T A G G T A C C A T G C T T C G T T G C T A G C T T C G T T G C A A G G T T G C A T C C T A G C A T C C A T G C A T C G A T G G T A G C A A G C A T G G T T G G T A G C T A C C A A G C A A G G A A C C T A G C T A C G A A C G T A C C A A G G T A G C T A C G A T C C T A G G T T G G A T G G T A C G A T G C T T C G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T G C T A C G A A C G T T G G T A C G T A C C T A C G A T G G A A C C T A G G A A C G A A C G A T C C A A C G T A G C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C G A T G G A A C C A T C C T A G G T T C G A A G C A T C C A T C G T A C C A T G C A A C G T T G G A T C C T A G G T A G C A T C C A A G G T A C G A T G G A A C C T T G G T A C G A A C C A T G G A T C C T A G G A A G C T A C C T A G G T A C C T T C G T T C G T A G C A T G G T A C C T T G G T A G C T T C G A A G G T A C C A A G C A T G C A A G C T T G C A A C G A A G G T A G C T A C C T T G C A A G G T T C C T A C G T A G G A T G G A A C C A A G C A T G G A T C C T T G C T A G C T A C C T A G G A A G G A A C C T T G C A T C C A T C G T T C C T T G G T T G G A A G C A A C C T A C G A A G C T T G C T T C C A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C G T T C C A T C C A T G G A T G C T T C C T T G C T A C G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C T T C G A A G G A A C G T A C G T T G C T A G C A A C C T A C G T A C G A A G C T A G G T A G C A A G G A T G C T T C C T T G C A T C C A T G C T T C C T A G G T A C G T A C C T T C G T A C G A A C G A T C G T A G G T A G C A T G C A T C G A T C C A A C C A A G G A A C C T T G C T A C G A A C G T A C C A T C C A A G C T A G G A A C G A A C G T A G C T A C C A T G C T A C C T T G C A T G G T A C C A A G C T A C G T T G C A A G G A T G C T T G C A T C C T T C G T A G G A A G G A A C C A T G C T A C C T T G G A A C C A A C G T T C C T T G G A T G G A A G G A A C G A A C C T T G G T A C G A A C G T T C C T T G C A A C G T T C G A A G C A A G G T T G C T A G C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C T A G C A A G C A A G C T A C C A T G C A A G C T A C C T A C C T A C G A T C C A T C G A A G C T A G G A T G C A T G G A T C G T T C C T A C G A A G C T A C C T A C G T A G C T T G G A T G C A T C C A T G C A A C C A A C C T T G C T T C C T T G G T A G C T T G C T T G C T A G C T A C C T A G C T A G G A A C G T T C C T A G C A T G C A A C C A A C G T +88 A C G T A G G T T C G T A G C A T G G A T C C T T G G T A G G A A C C A A C G A A G G A T G C A A G G A A G G A A G C T T G G T A C C T A C C T T C G A A C C T T G C T A G C A T C G A T G G T T C G T T G G T A C C A T C C T A C C T A G G T A G G A T G C A A C G T A G C T T C C T T C C T T G G T T G C A T C G A T C C T T G G T T C C A T C G T T C C A T G C A A G C T A C G A A G C T T C G T T G C T A G G A A G C A T C G A A G G A T C C T A G C A A C C T T G C A A G C T A G C A A G G T T C G T A C C T T G G T T G G T A C G T T C C A T G G T A C G A A G G T T C C A A C G A A C G A A G G A T G G A T G G T T G G T A C G A T G C T A C G A A C G T A C G A T G C A T C G A A G G T A G G T A G C T T G G A A G G T A C G A T G C A T C G A A G G A A C G A A C G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T C G T A C C A A C C A A C G T T G G A T C C A T G C A T C C T T G G A A C G A T C C T T C C A A C C T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T A C C A A C G A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A G C T T G G T A G C T T G G A T C C T T G G T A G G T A C G T A G C A A G C A T G C A T C G T A C C A A G C T T C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G G A A C C T A G C T T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A G C A A G G T T C G A T G G A A C C T T C C T A G G T A G C T T C C T T G C A T G C T A G C T A C G A T C G T T G G A T G C A T G G T A C G A T G G T T C C T A C G T A G C A A C C T A C G A A G G A A C G T A C G T T G C T A G C A A C C T A C G T A C G A A G C T A G G T A G C A A G G A T G C T T C C T T G C A T C C A T G C T T C C T A G G T A C G T A C C T T C G T A C G A A C G A T C G T A G G T A G C A T G C A T C G A T C C A A C C A A G G A A C C T T G C T A C G A A C G T A C C A T G G T A G C T T C G A A C G T A C C T A C C T T G C T A G C T A C C A A G C A T G G T T G C A A C C A A C G T T G C A T G G A A G G T A C C A T C C T T C G T T G G A A G C T T C C A A G C T A C C T T C C A T C C A T G C A A G G T T G C A T G G T A G G A A G C T A C C T T G G T A C G A A G G A T C G T T C G T A C G T A G C A A G C A T G G T T G G A T C C A A G C A A C G T T G G A A G G T T G G A A C C T T G C T A G C A A G C T T G C A A G G A A C G A A C C A T C G T T G C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C G A A G C T T G C T T C G T T C C T T G G T T C C T T G C T T G C A A C G A T G C T A G C A A G G A A C C T A G G T A G G T A G C A A C G T +89 A C C T A G G A T G G T T C C T A C C T T C C A A G G T T G G T A C C A A G G T T G C T T G C T T G C T T G G A A G C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A A C C A T G G T A C G T T G C T A G C A T C G T A C G T A G G A A C C A A G C T T C C A T G C A A G C A T C G T T G C T T C C A A C C A T C C T A G C A T C C A T C C T T C C A A G G A T G C T A C C T A C G T T C G T A C G T A G C A T C C A A G G A T G C T A G C T A G C A A G G T A C C T A G C A A C G T A G G T A C C T A G C A T C C A A G G T T C G T A G C T T G G A A G C A A G G T T C C A A C C A T G G T A G G A T G C T T G C T T G C A A C C A T G C A A C C A A G G T T C C T A G C T T C G A A G C T A G G A A C G T A G G A A C G T A C G A T G C T A G C A A C C T T C G T T C G A A G C A A G G T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A G C A A G G T A C C T T G G A A G C T A G G A A G C A A G C A T G G T A G G A T G G A A G G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A T G G A A C C A A G C T A G G T T C G A T G C T A C C A A G G T T C C T A C G T A G G A T G G A A C C A A G C A T G G A T C C T A C G T A C C T A C G T A C G A A G C A T G C T T C C T A C G A T C C T A C G T T G G T A G G A A G G A A G C A T C G A A G C T T C C A T C G A A G C A A C C A A G C T T G C T T C C A T C G A T C G T A C C A A G C A A G C A T G G A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A C C A A G C T T C G T T C G A T G G T A C C A T G C T T C G A T C C T A C G T A C G A A G C T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C G T A C C T A G C A A C C T T C C T A G G A T C G T T C G T A G G A T G C T T G C A T C C T T C C A A G C T A G G A A C C T T G C T T G C A A G C A T G C T A G G T A G G A T G G T A C G T A C C T A G C T A G C A A G G A A G C T T G C A T G G T A C C A A G C T A C G T T G C A A G G A A G G T A G C A T C C T T C G T A G G A A G C T A G C A A G G T T G G T A G C A T C C A A C G T T C C T T G G A T G G T A G G A A G C A T C G A T G G T A G G A A G G T T C C T T G C A A C G T A C C A A G C A T G C T T G G A T G C A T G C A A G G T A C G A A G C T T C C A A C C A A G G T A G C A A G C T T G C A A G C A A C G A A C C T A C G T A C C T A G C A A C C T A G C A T C G A T G G A T C C T A G G A T G C A T G G A T C G A A G C T A C G A T G C T T G C A A C C T T G C T T G G A A G C T A C C T T G C T A C C A A C G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G C A A G C A A C C T A G C T A G C A A C G T A C C T +90 A C C T A G G T A C G T T G C T A G C T T C C T A G C T A G G T A C G A A G G T T G G T A G C A A C G A A G G A A C C A A G G T A G C A T G C A T G C T A G C T A G G T A G C A T G C T T G G T T C C T T G C T A C G A T C C A T C C T A C G A A G G A T G G A T C G A T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A T C C A T C G A A G G A A G G A A C G A A G C T T C G T A C G T A G G A A C G A A G G T A G C T A G C T A C G A A C G A T C C A A G G T A G C T A G G T T G G T A G C T T C C A A G G T A G G T T G C T T G G A A G G A A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C A A C C A T G C A A C C A A C G T A C G T A C C T A C C T A C G A T G C A A G C T A G G A A G G T A C C A T G C T A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T C C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G G A T G C A A G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T A C C T T C G T T G C A T C C A A G C T A C G T T G G A T C C A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T C G A A G C T T G G A T C C T T G C T A G C A A C G T A G G A A G G A A C C T T G C A A G C A T C G T T C C T T G G T A G C A T G G A A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A C G A A C G T A C G A T C C A A G C A T G G A A G C A A C C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A C C T A C G T T C G A A G C T A C C A T G G A T C G A A G C T T C G A T C G T T G C A A C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G T A G G T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C T A C G A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T T G C T A C C T T C C A A G C A A G C A A C C A A C C T T G C T A G C T A C G T T G C T A C C A T C C A T C G T T G C A A G C T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A T C C T A C C T T G G T A C G A A C C T T C C T A G C A A G C A T C C T A G C T A G G T T G G A T G C A A G C T A C G T T G C T T C G A A C C T T G G T T G C T A G G T A G C A T G C A A G G A A C C T A C C T T C G T T G C A A G C T A C C T A G G A T C C A T C G A A G C T T G G A T G C T A G C A T G G T T C C T A C C T A G C T A C C A A C C A T G G T T G G A A G C A T G C T T G C A A C C A A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G T A C C T A G G T T G C A A C C A A C G T +91 A G C T T G G A T G C T T C C T A C C T T G C T A G G T A G C T A C G A A G G T T G C T T G C T T G G A A C G A A C C T A G G T A G C A T C G A T G C T T G C A T G G T A G C A A C C A T C G T T C C T T G C A A G C A A G G T A C C A A G G A T G C A T C C T A C C A T G C T T C C T T C C T T G C T T G C T A G C A T C G T A G C A A G G A T C G T A C C A T G G T A G C T T C C T T C G T T C C A A C G A A C C A A G G T A G G T A G C A A C C A A G C A A C G T A C C T A G C T A G C T A C C T T C G T A C C T T G G A T G G T A C C T T C C A A C G A A C G A A G G T A G C A A C G A T G G A A G G A T G C T T C C T T G C T A C C T T G C T A C G A A C G A A C G A T G C A T C C T A C C T A C C A A C G T T G G A A C G A A C G T T C C A A C G T A C G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G C A A C G T T C C A T C C T A C C T A G C A A C C A T C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A T C C A A C G A A C G A A C C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A C C T T G G A T G C A T G G A T C C T A C C T A G G T A C G T A G C T T G C A T G C T T G C T A C G A T C C T T C C T T G G T T G G T T G C A A G C A T C G A A G C T A G C A T C G A A G C A A G C A A G C A T G C A A G G T T G C A T C C T T C C A T C C A T C C A T G G A A G C T T G C T A G C T A G G A T G G T A C C T T C C T A G G T A C G T T C C T A C C A T G C T A C C T T G C A T C G A T G C T T C G A T G C A A C G T A G G T T G C T A G C A A C C A A G C T T G G A A G C T A G G T A C C A T G C T T G C A A G C T T C G T A G G T T C G T A C G A A C C A A G G A T G C T T C C A A G C A T C C A T G G A A G G T T G G A A C G T A G G T T C G T A C C T A C C A T C G T A G G A A C G A T G C A T C C T T C G T A C C A T G G A A C C T T G C T T G C A A C G T A C C T A G G T A G G A T G G T A C G A A C C T A G C T A G C T A G C A T C C T A G C T T C G T A C C A T C C T A C G T T G C A A G G A A C C T A C C A T C C A T G G A A G G A A G C T A C C T A G C T T G G T A G G A A C C A T G C A A G G T T G C A A G C T T G C A A G G A A G C T T C G A T C G T A C C A T C C T A G C A A C G T T G C T A C C T A G G T T C G T T G C A A G C T T C C T T G G T A C G T T C C T A G C T T G C T A G G A A G C T T G G A A G G A A C C T A C C T T C G T A G C T A C C T A C G T A G C A T G G A T C G A A G C T T G C A T G C T A C C A T G C T A G C T A G G T A G G A T G C T A C C A T G C T T G G A T G C A T C C T T C C A A C G A A G C T A G C A A C G A A G C A A G C T T G C T T C C A A G C T A C G A T G G T A C C A A G C A A C C A T G C T A G C A A G G T A C C T +92 A C C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T A C C A A G G T T C C T T G C A A C G A A C G T A G C T A C C T A G C A T C C A T G G T A G C A T G G T T G C A A G C A T G G A A G G A T C G T A C G A T C C A T C C T A C G T A G C A T C G T A C C A T G C T T G C T T C C A A G G A T G C A A C C A T C C T A G C T T C C A A C C T T C G A T G C A T G C T A C C A T G G T T C C A A G C T T G C A A G C A A C G T T G C A A G C T A G C A A C C T T G C T A G G T A G G T A G G T T G G T A G G T T G G A A G G T A G G A T G C T T C C A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C T A G G T A G G T A C C T A G G T A C G A T G C A T C G T A G C A T C C T A C G T A C G A A G G T T C G T T C G A A G C T T G C A T G G T T C C A T G G T A C C A T G G T A G C A A G G A T C G A T C G A A C C T A C G T T C G T T G C A A C G T A G G A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A A C C T A G G T A C G T T G C A A C G T A G G A A C G A A C C A T G G A T C C A T G G T A G G T A C C T A G C A A G C T T G C A T C G T T G C T A C G T T G G A T C C T T G G T A C G T A C G T A C C A A G C T A G C A T G G T T G C A A C G T A G G T T C G A T G G T A G C A T C G T T C C T A C G T A G G A A C C T A C G T A C C T T G G A T C G T T G G T T G G T T C C T T G G T T G G T A G C T T G C A T C C A T C C T T C G T T G C A A G C A T G G T A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G G T A G C T T C C A T C C A A C G A A C C A A G C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G T T C C T A G G A A G C A T C C A A C C A T C C T A C C A T G C T T C G A A G C T A G C A T G G T A C G A T G G T A G G T A C C A A C C A T G C T A C G T T C C T A G G T A G C A T G G A T G C A T C C A T C G T A G G T T C G T A C G A A C C T A G G A T G C T T C C T T C C T T C C A T G G T T C C T A G G T A C C A A G C T A C C T T C C A T G C A T G G T A G G T A G C A A C G A T C G A T C C T T G C T T C G T A G G T T G C T T G G T T G G A T G C A T G G T A C C T A G G T A C G A A C G T A G C T A C C T A G C T A C C A A G C A T G G T A C C A A G C A A C G T T G C A T G G T T G C T A C C A T C C A T G G A A G G A A G C T A G C T A G C T A C C T T G C A T C G T T G C A A G G T T G G A T G C T T G G A T G C A T G G A T C G A A C G A A C G T T G C T T C C T A G C A T C G A T G C T A G G T T G G A T G C A T G C T T C G A A C C A A G C T T C C T A G C A A C G T T C G T A G C A T G C A A G G A A C G A A C C T T C C T A C C A A C C A A C G T A G C T T G C A T C G A T C C T A G C T T C G A A G C A T G G T T C C T A C G A A G G T A C C T T G C A T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T T C C T T C C T A G G T T G G T T G C T A G C T A C G A T G C T A G G A T G C A T C C T A G C A T G C A A C C A A C G T +93 A G C T A C G T T G C T A G C T A C C T T C G A A G G T A G C T A C C A A G G T T G G T T G C T T G G T T C G A T G C T A G G T A G C A T G C T T C C A A C C T T G C T A G C A T G C A T G G T A G G A T C G T A G C A T G C T A C C A A G G A A G C A T C C T T C G A A G C T A G C T T C C T T G C T T G G T A C G A T C C T A G C A A G G A A C C T T C C A A C G A A G C T A C C T A G C T T G G T A C C T T G C A A G C A A G G A T G C A A G C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T T G G T T C C T T G G T T C C A T G C T A C G A A C G A A G C T T C C A A C G A A G C T A G G A T G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A T C C A A C G A T G C T T C G T A G C T T C G A A G G A A C G A A G G T T G G T T C G T T G C T T G C A T G G T T C C A T G G A A G C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T G G T A G C T T G G A A G G T A G C A T G G A A G C T A G G A A G C A A G C T A G G A A G G T A C C A T C G T A C C A T G G T A C G T T G C T A C G T T G C T A C G A A C C T A G C T A C C A T C G T A G G T A C C A A G G A T G C A A G G A A C C A A G G A A G C A A G C T A C C T T G C A T C G T T C C T A C G A A G G A A C C T A C G T T G C A T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G C A A C C A A G C A T G C A A G G T T G C A T C C T T C C A T C C A T C C A T G G A A G C T T C C T A G C T A G G A T G G T A C C T T C C T A G G A A G C A T C C A A C C A T C C T A C C A T G C T T C G A A G C T A C G A T G G T A C G T A G G T T G C T A G C A A C C A A G C T A G G A A G C T A G G T A G C A T G G A T C G A T C C T A C G T A G G T T C G A A C G A A C C T A G G A A C G T T C C A T G C T T C C A T G G T A G G A T G G T A C C A A G G T T C G T A C G T A C C T T C G T A G G T A G C T A C G A T C G A T C G T A C C T A C G A A C C T T G C T T G C A T G G A T G C A T G G T T G C A T G G T A C G T T C G T A G C T A C C A T G G A A C C A A G C A T C C T T G C T A C C T T G C T T G C A A G G T T G C T A C C A T C C T T C G A T G G A A G C T T G C A A G C A A C C T A G C A A C G T T G C A A G C A A G C A T G G A A G G A A C G A A G G T T C G A A C G T A C C T T G C T T C G T A G C A T C C T A G C T A G G T T G G T T G C T T C G T A C C T T G G T T C G T T C C T A C C T A C G A A G G A A G C T A C C A A G G A A G C T A C C A T C G T T G C T T C G T A C C T A C C A T C C A T C C A T C C A T C C A T G C A T C C A T G G T T C G T A C G A A G G T A G G T A G C T T G C A T G G A A G C A T C C A T C C T A C C A A G G T T G C T A C C T T C C T A G G T T C C T T C C A A G C T A C G A T G G T A C C A A G C T T C G T A G G T A C C A A G G T A C C T +94 A G C A A C G T A C C T T C C T A C C T T C G A A G G A A C G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C T T C C T T G C T T G C T A C C A A C C A T G G T T C G T T G C T A G C A T C G T A C G T A G G A A G C A T G C T T C G A T G C A A C C T T C G A T G G T A G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A C C T T G C A A G C T A G G T A G C T T C C T A G G T A G G T A G G T A C G T A G C A T G G A A C G T A G C T A C C A A C G A A G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A G G A A C C T A G G A T C G T A G G T A G G A A C G T A G G A T C G A A C G T T C C A A C G T A C C T T C G T A C G T A G G A A C G T T C G T A G G T T G C T T G C T T G G T A G C T T C G T T C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T T G C T T C C T A G G T A G C T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A G G T A G C T T G G T T G C T T C G A T C C T T G C T A G G T T G C T A C C A A G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C A A G C A T C G A A G C T A G C A T C G A A G C A A G C T T G C A T G G T T C G A T C G A A C C T T C G T A G G A A G C A T C G T A G C A A G C A A G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C G A A C C A A G C T A C G T T C G A A C G A A C G A A G C T T G C A T C C A T C G T A G G T T C G T A C G A A C C T A G G A T G C T T C C A A G C A T C C A T G G A A G G T T G G A A C G A A G G T T C G T A C C T A G G A T C G T T C G A T C C T A C G A T C G A A C C A A G C T A C G A A G G T A G C T A C G A T G G T T G C A T G G T T G C T A G G A A C G T A C G T A G C T A G C T A C G T T C C T A G C T T C G T A C C A A C C T A C C T T G C A A C G T T C C T T C G A T C C A T G G A A G C A A G C T A G C A A G C A A C C T A G G T A C C A A C G T T C C T T G C A T G G T A G G A T G G A T G G A T C G T A G G T T C G T T C C T T G C A A C G T T G C A T G C T A G C T T G C T A G C A A G C A A C G T T G G T A C G A A C C T T G G T T G C A A G C A A G C T A G G A A G C T T C G A A C C T T C G T T C C T T C C T A C C T A C C A T C G A A G G A A G C A T C G A T G C A A C G A T G G T T C C T A C C A A C C T A G G T A G C T T G C A A G G A A G C A T C C T T G C T A C G A A G C T T G G T T C G A A G C T A G C T T G C T T C C T A G C A A C C T A G C T A G G T A C C T T C C T A G G T A G G T A G C A A C G T +95 A C C A A G G T A C G T T G C T A G C T A G C T A G G T T G G T A G G A A G G T T G C T T G C T T G G A A C G A A C C A A C C T A C C T A C C T T G C A A C C T T G G A T C C A T C C A T G G A A C G T T G G A A G G T T C G T T C G A A G G T T G C A A G C A T C C T T G G T A G C A A C C T T G C T T C C T T C C A T C C A A G C A A G G A T G C A T C C A T G G T A G C T A C G A A G C T T C G T A C C A T G C A A G C A A G G A T G C A A G C T A G G A A C G A T G G A A G G T A G C A A G G T T G G T T G G T T G G T A G G T A G G A T G C A T G G A A C G T A G C T T G C A A C G A A G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A C G T A C G T A G C T A C C T A G C A T C C A A G C A T G G A A G G T A C G A T C G T T C G T T G G T T C G T A C G T A G G A A C G T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A C C A A G G T A C C T T G G A A G C T A G G A A G C A A G C A T G G T A G G A T G G A A G G T A C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T T C C A A G C T T C G T T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T A C G T A G C T A C C T A G G A A G C T A G C T T G G T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C C T T G G A A G C A T G G T A G G T A C C A A C G T A C G A A C G T A G G T T C C A A G G T A C C A T C C A A C C A T C C T A C C T T G C A A C G A A G C T A C G T T C G T T C G A A G G T A C C A A G C A A G C A A G C T A C C T T C C T A G G A A C C A T G C T T G C A A G C T T G G A A G G A A G C T A C G A A C C A A G G A T G C T T G C T A G C A T C G T A G G T A G C T A G G T A G C A A C C A A G C T A G G A T G G A T C G T A G G A T G C T T G C A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A T C C A A G C A A G C A A C C A A C C T T G C T A G C T A C G T T G C T A C C A T C C A T C G T T G C A A G C T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G C T A C C T T G G T A C G A A G G T T C C T T G C A A C G T A C C A A G C A T G G T T G G A T C C A A G C A A C G T A G C T T C G T T C C T A G G T A G G T T C G T A G C T A C G A A G G A A G C T T C C A T C G T A G C A A C C T A C C A A G G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C C A A C G A A G C T T G C T A C G A T G C T A G G A A C G A A C C T A G C T A C C T A G C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C A T C C A A G C A A C C T A G C T A G C A A C G T A C C T +96 A C C A A G G T A C G T T G C T A G C T A G C T A G G T T G G T A G G A A G G T T G C T T G C T T G G A A C G A A C C A A C C T A C C T A C C T T G C A A C C T T G G A T C C A T C C A T G G A A C G T T G G A A G G T T C G T T C G A A G G T T G C A A G C A T C C T T G G T A G C A A C C T T G C T T C C T T C C A T C C A A G C A A G G A T G C A T C C A T G G T A G C T A C G A A G C T T C G T A C C A T G C A A G C A A G G A T G C A A G C T A G G A A C G A T G G A A G G T A G C T A G G T T G G T T G G T T G G T A G G T A G G A T G C A T G G A A C G T A G C T T G C A A C G A A G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A C G T A C G T A G C T A C C T A G C A T C C A A G C A T G G A A G G T A C G A T C G T T C G T T G G T T C G T A C G T A G G A A C G T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A C C A A G G T A C C T T G G A A G C T A G G A A G C A A G C A T G G T A G G A T G G A A G G T A C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T T C C A A G C T T C G T T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T A C G T A G C T A C C T A G G A A G C T A G C T T G G T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C C T T G G A A G C A T G G T A G G T A C C A A C G T A C G A A C G T A G G T T C C A A G G T A C C A T C C A A C C A T C C T A C C T T G C A A C G A A G C T A C G T T C G T T C G A A G G T A C C A A G C A A G C A A G C T A C C T T C C T A G G A A C C A T G C T T G C A A G C T T G G A A G G A A G C T A C G A A C C A A G G A T G C T T G C T A G C A T C G T A G G T A G C T A G G T A G C A A C C A A G C T A G G A T G G A T C G T A G G A T G C T T G C A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A T C C A A G C A A G C A A C C A A C C T T G C T A G C T A C G T T G C T A C C A T C C A T C G T T G C A A G C T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G C T A C C T T G G T A C G A A G G T T C C T T G C A A C G T A C C A A G C A T G G T T G G A T C C A A G C A A C G T A G C T T C G T T C C T A G G T A G G T T C G T A G C T A C G A A G G A A G C T T C C A T C G T A G C A A C C T A C C A A G G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C C A A C G A A G C T T G C T A C G A T G C T A G G A A C G A A C C T A G C T A C C T A G C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C A T C C A A G C A A C C T A G C T A G C A A C G T A C C T +97 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G C T A C C A A G G T T G G T T G C T A G G T T C G A A C C T A C C A T G C A A G C A A C C T A C C T A G C T A G C A T C G T T G G T A C G A T G C T T C C A T C C T T C C T A C C A A G C A T G C A A C C T T G G A A C C T T C G T A G G T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A T G G A A G C T A G C T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A G C A T G C T A G C T A G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C G T A G C T T C G T T C G A A C C T A C G T T C G T T C G T T G C T T G C A T G G T T C C A T G G A A C C A A C G A A G G A T G G T T C C A T C G A A C C A T C C T A G G T T C G A T C C A A C G A T G G T A C C A A C C A A C G T T G C A T C C A A G G T A G C A T C C A A G G T A G G A T G C A A C C T A G G A A G C T A G C A A C C T T G G T A G C A A G C A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C A A G G A A G C T A G G T A C C T A G C A T G G T T C C T A C G A A G G A T C G A A C G A T G C T T C G A T C C T T G C T A G G T T C C T T G C T T G C A T G C A T C G T A C C T T C C T T G G A T G G T A G G A A G G A A C C T A C G A T C G A T G C A T C C A A C C A A G C T T G G T A G C T T C C A T C G A A C C T T C G A T C G A T G C A T G G A A C C A A C C T T G C T A C G A T G G T A C C T T C C T A G G T A C G T T C C A A C C A T C C A A C G A T G C T T C C A A G C A T C G T T G G A T G G A A G G T A G C T A G C A A G C A A G C T A C C T T C C T A G C T A C G A A G C T T G C A A G C T T C G T A G G T T C G T A C G A A C C A A G G A T G C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A A C G A T C G T A G G T A G C A T G G A T C C T T C G A A G C T A C G T A G G T T G C T T G C A A C G T A C C T A G G T A G G A T C G T A C G T A C G T A C C A T G C T A C G T T C C A A G C T T C G T A C C A A G C A A C G T T G C A A G G A T G C T A C G A T C C A T C G A T G C A A G G T A G C T A G C T T C C T T C C A A C C A T G C A A G G T T G C A T G G T A G G A T G C T T G G A T G C A A G G A A C C A T C C T T C G T A C G T T C G A A G C T A C G T T G G A T G C T A G C T T C C A T G G T T C G T T C C T A C C A A C G A T C G A A G C A T G C A A G G A T C G A A C C A T C G A T G C T A G G T A C C T A G G A T C G A A G G A A G C T T G G A T G C T A C C A T G G T A C C T A G G T A G G A T G C T A G C T T C C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T T C G A A G G A T G G T T C C T T C C T A G C T A G C T A G C A A C G A A G G A T C C T A G G T A G G T A G C A A C G T +98 A C C T T G G A T G C T T C C A T G C T A G G T A G G T A C G T A C C T A C G T A G G A T G C T A G C T T G G A A G C T T G G T A G C A T G C T T G C T A G C A T G C T A G C A T C G A T G G T T C G A T G G T A G C A T C C T A C G T A G G A T G G A T C G A T C C A T G G A A G C T T G C A A G C T T G C T T G C A T C C T A G C A A G G A T G C A T C G A T G G A A G G A T G C A A G C T A C G T T G G T T G C A A G C A A G G T A G C T A C G T A G C A A C G A T G C A A G C A A C G T A G G T T G C T A G C T T C C T T G C T A C C T T C C T T G G A A C G A A G G T T C C A T G G A A G G A A G G A T G C A A C C T T G C A A C G T T G C A A C G A A C G T A C G A T G C T A C C T A G G T A C C A A C G A A G G A A C C A A C G A A G G T T C G T A G G T T C G A A G G T A C G A A G G T T G G T T C G A A G C T T G C A T G G T T C G T T C G T A G C A A C C A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T A C G T T C C A T C C A A G G A T C C T T C C A T C G T A G C T T G G T A C C T A G C A A G G T T C C A T C G A T C C A T G G A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C A T C G T A C G T A C C A A G C A T G C A A G C A T G C A A G C T A G G T T C G A T G G T A G C A T C G T T C C T A C G T A G G A A G C T T C G T A G G T T C G A T G C T T C C T A G G T A C G T A C G A T G G T A C G T T G G T A G C T T C C A T C C T T G G T T G G T T G C A A G C A T C G A A G C T A G C T T C C A A C C A A G C A A G C A T G C T T C G T T C G A T C C T T C C A T G C A A G C A T G G A A G C T T C C T T G G T T G C A T C C A A C C T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C T A G C A A C C T T C C T A G G A A C C A T G G T T C G T A C C T A C G A T G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G T A G G T T G G T A C G A T G C T A C C T A C G A T G G A T G G T A G G A T G C T T G G A T C C T T C G A T C C T A C G A A G G A A G C T A C C T A C G T T G C T A G G T A G G A T G G T A C G A T C C T A G C T A C C A T G G A A C C A T G C A T C G A A C G A T C C T A C G T A G C T T G G A A G C T A G C A T C C A T G C T T G C A A G G A A C G T A G C T T G C T T G C A A C G A T G C A A G G A A G C A A G G A A G G A A G C A A G C T T C G T A G G A A C C T T C C T T G C A A C G T A G C A T G C A A G C A T G C T T G C T T G C A A G G A A G G T T C G T T C C T A G G T T G C T A G G A A G C A T G C A A G G A A C C T A C C A T C G T T G C A A C G T A C C A A G G A T G G A T C G A A G C A A G G A T G C A A G C A T G G A T C C T A C C A A G G A T G G T A G C T T G C T T G G T A G C A T G C A T G C A A G C A A C G T T C C T A C G T T G C A A G C T T G G A T G C T A G C T A C G T A G C T T C C T A G G A A C C T A G G T A G G T A G C A A C G T +99 A G G T A C G T A C C T T C C T T G C T T G C T T G C A A C G T T C C A T C G A T G C T A G C T T G C A T C G A T C G T T G G T A G C T T C G A T C C T A C C T T G G T T G G A T C C T T C G T T G G T T C G T A C G A T C C T T C C T A C C A T G G A T C C T T C C A T G C A A C C T T C G T A G G T T G C T T C C A T C C T T G G A A G G A T C C T T G C A T G G T A G C A A G C A T C G T T C G T A G C T T G C T A G G A A G G A A C C T A C C T T C G A A C G T T G C A A G G T A G C T A G G T T G G T A G G T T C C A T G G A A C C T A G C T T G G A A C C A A G G T A C C A A C G A A G G T T G G A T G C T T C G T T G G A A C C A T G C T A C G A A C G T T G G T A C G T A C C T A G G A T G C A A C C T A G G T A C G T A C G A T G C T A C C T T C C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G G A T G C T A G C T A C C T T G G A A G C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T T C C A T C C T A G C A A G G A A G G T T C C A A G C A T G G T T C C T A C G A A G G T A G C T T C G T T G G T T G G A T C C T A G C T A G G T A C G T A G C A A G G A A G C T T G C A T C C A T C C T T G G A A G C T A G G A A G C A T C C T A C G A T C G A T G G T T G C A A C C T A C C T T G C T T G G T T C G A T C G T T C C T A C G T T G G A A G C A T G C A A G C A A C C T A G C T A C G A A C C A A C G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A G G T A G C A A C C T A C G T T C C A A G G T A C C A T G C A T C G A T C C T A C G T A G G T T G C A T C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G T T C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G C T A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T T G G T T G G T A C C A T C C T T C G A A G C A A G C T A G C A A C C T T G G T A G G A A C C A T C G T T C G T T G C A T G G T A G G A A G C T T G G A T G G A A G G T A G G A T C C T T C C T A C G T A C C A A C C T A C C T T C G T T C C T T G C T T C C T T G C T A G G T T G G A A G G T T G C T A C G T A G C T A G G A A C C A A C C T T C C A T G G A A G C T A C C A T C C T A C C T T G G A A C G A T C C A A G G A T G C A A C G A T G G A T C G A A C G A A G G T T G C T T C C A T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G T A G C T A G C A T G C A A G C T A C G T +100 A G G A A C G T A C C T T G C A T G C T A G C T A G G T A C C T T C C T A C G A T C C T T G C T A C G A T C G A A G C T A G G T A G C A T G G T T G C A A C C T T G C T A G C T T G C A T G G A T G G T T G C T A C C A T C G T A C C A A C G A A G C T T G G A T C G T A G C A A G C T T C C T A G G T T G G T T G C A T C C A A G C T T C C A T G C A T C G A A G G A T G C T A C G T T C G T T C C A A C G A A C C A A G C T A G G T A G C A A C C T A C G A A C G T T C C T T G C T A G C T A G G T T G C T A G C T T C C A T G C T A C G T A G C A T G G A A C G T A G C T T C C T A C C A T G G T A G G A T G C T T C C T T G G A A C C A T C C A T C G A A C G A A G G A T G C A T C G A A G G T A G C A T C G T A G C T T C G T A C G A T G C A T C G T T C C A A G G T T C G A A G C A A C G T T C G T A G G A A G C T T G C A T G G T T G C T T C G T A C C A A G G A A C C A A G C A T G G T T C C A A G C T A G C T A G G A A C G A A G C A T G C A T G C T A C C A T G G T A C C T T G G A T C C T A G C A T C C T T G G A A G G T A C G T T G G A A C C T A G G T A G G A A C C T T C G A A G G A A G C A A G C T T C G A T G C A A G G T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C T A G C A A G C A A G C A A G C A A C C A A G G T T C G T A G C A A G G T T G C T A C G A A G G T A G C A A C G T A C C A A G C T T G C T A G C T A G C A A C G T A C G T A G G T A C C T A G C A T C C A T C C T T G G A T G C A A G G A A G C A A G C A T C G A A G C T A G C A T C C A A C C A A G C A A G C A T G C T T C G T T C G A T C C T T C C A T C G A T G C A T G G A A C C A A C C T T G C T A C G A T C C A A C C T A G G A A G C T A C C A A G C T T G C T T G C T A G C T T C G A T C G A A G C T A C G T T C C A A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C T A G G T A C C A A G C A T C G A T C C T A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C A T G G A A C G T A G G T A C C A A G G T T C C T A C G A T C C T A C G T A G G A T C G T T C G A A C C T T C G T A C C T A G G A A G G T T G G T A C G T A G G A T G C A T C C T A G C T A G G T A C G T T G G A T G C T A C C A T G C T A C C T T G C A T G G T A C G T A C C T T G C T T G C T T G G A T G C T T C C A T C C T T C G T A G G A A C C T A G C A A G C T T C C T T G G A A C C A T C G T T C C T T G G A T G G A A G G A A G G A T G G A T G G A A G G T T G C T T C C T T C C T A G C A T C C T A C C T A G G T T G C A A G C T T G G T T C C T T G C T T C G T T C C T T C C T T G G A T C G A A G C A T G C A A G G T T C G A T C C T T C G T T G C A A C G T T C C T A C C A T G C A T C G A T C C T A G G T T C G A A G C A T G G A T G C T A C G T A G G A A C C A A C C A T G C T T G G A A G G T T C C T T C C A A C C A A G C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +101 A C G T A C G T A C G T A G C A A C G T A G C T T G G T A C G A A C C A A G G A T G C T T G C T A C G T T C G A T G G T T G G T T G C T T G C T T G C T A G C T T G G T T C C T T C C A T G G T T G G T T G G A A G C A T C G T A G G T A G G T A C C A T G C A A C C T T G C T T C C A A C C T A G G T T C C T T C C A T C C T A G C A A G G A A C C T T G C T T G G A T G C T A C G A T G G T T C G T A G C T T G C A A G C T A G G T T G C A A C C T A G G A A C C T T C C T A G C T A G C T A C C T T G G T A G C A T C C A T G C T A C G T A G C T A C G A A C G A A G G T T G C A A C G T T G G T T G G T A G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G A T C C T A G G T A C C A A G C A T G C T A G G T A C G A T G G A A C G T A G C T T C G T A C C A A G G A A G G T T G G T T G G A A G C T T G C A T G G T T C C A T C G T A C G A A G G A A G C A A G C A T C C T T C G A A C C T A G C T A G G A A G G A A G C A T G C A T G C T A C C A T G G T A C C T T G G A T C C T A G C A T C C T T G G A A G G T A C G T T G G A A C C T A G G T A G G A A C C A T C G A A G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C T A G G A A G G A A G G T T C G A A G G A A G G T T C C A A C C A A G G T A C C T T G G T A C C A A G C T T G C T T G C T A G C A T C C T A G C T T G C A T G C A T C C T A C G T T C C T T G G A T G G T A G C A A G G A A C C T A C G A A G C T A G C A T C G T A C C T A C C T T G C T T G G T T C G A T C G T T C C T A C G T T G G A A G C A T G C A T G G T A C C T T G C T A C G A T G G T A C C T T C C T A G G T A C C A T G G T T C G A T G C A T G C T T G C A A G C A A G C A T G C T T C C A A C G A T G C T A G C T A C G A A C C A T G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A A C C T A G G A T C C T T G C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G G T A C G T A G G A T G C A T C C T T G C T T G G T A C G T T G G A T G C T A G C A T G C T T C C T T G C A T G C A T C C A A C C A A C G T T G C A T C G T A C C T T C C A T C C T T C G A A G G A A G C T A G C T A C G T T C C T T G C A A C C A T G C A A G C A T G C A A G G A A G G A A G C T A C C T T G G T A G C A T C G T T C C T T C C T A G G T A C C T A C C T A G C T T C C T T G G A A G C T A C G T T G G T T C G A A C C T A G G T T G C T T C G A A G C T T G G A A G C A A C C T T C C A T C G A A C C A A C C T A C G T T C G T T C C A T C C A T G C T T G G A T G C T A G C A T G C T T G C A A C G A T G C T T G C T A G C T T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C A T C G T T G C A A G C T T G G T T G C T T G C A A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +102 A G G T T G G A T G C T A G C A A G G T T G C T A G G A A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T A C C T T G C A A C C T T G G T A G C A T C G A T C G A A G C T T G C T T G G A T C C A A C C A A G G A A G C A T G C A A C G T T G C A A C C T T C C A A G G T T G C T T G C A T C C T A G C A T C C A T C C A T C G A T G G T A G G A T G C T T C G T A C G T A G G A A G G A A C C A T G G A A C C T A C C T A G C A A G C T A C C T A G C A A C G T A G G T T C G A A G C A T C C T A G G T A C G T T C C A T G G A A C G T A G C T A C C A A C G A T G C T A C G A T G C T T G G A A G G A A C C T T C C A T C C T A G G A A C G T A G C T T C G A A G C T A G C A A C C T A G G A A C G T A C G A T G C A A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A T C C A A G G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G G A T G C A A G C T T C G A T G C A A G G T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C A T G C A A G C A A G C A A G C A A G G T A G G A T G C T A G C A T G G A T C C T A C G A A G G T A G C T T C G T T G C A T G G A T G C T A C C T A G C A A C G T T C G T A G G T A G C T A G C A T C C A T C C T T G G A T G C T A G G A A G C A A G C A T C G A T G G A T C G A T G C A A C C A A G C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T G G T A C C T T G C T A C G A A G G T A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A T C C T T G C A A C C T T C G T A G G T T C G A A C G A A C C T A G G A T G C T T G C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A T G G A T C C T T C C A A G C T A G G A A C G A T G G T A G C A A C G A T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C A A G C T T C C A T G C A T C C T A C C A A C C T T G C T A G C A A G G T A C G T T C C A T C C T T C G T T G G A A G G A A C C A T G G T T G G T A G C A T C C A T G C A T G G T T G G A T G G T A C G A T G C T A C G T T G G A T C G T A C C A T C C T T C C T A G C A T G G T A C C T A G C T T G G A T G C T T C G T T C C T A G C T A G G T T C C T T G G T A G C T T C G T A G C T A C G A A G G A A G C T T C C A T C G T T G C A A C C T A C C T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G G T T G C T A C C A T G C T T G G A A G C T T C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C A A C C T A C C T A G G T A G G T A G C A A C G T +103 A C C T A G G T T C C T T G C T A C C T T G C T A G G T A G G T A G C A A G G T T G C T T G C T T G G A A C G A A G C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A T C C A T G G T T C G A T G G T T C C T T G C T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G C T T C C A T G G A A G G T T G G T T G C A A G C T T G C T A C C A T C C A T C C T A C G A A C G A A G C A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C G T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A G G A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T C C T A C C T A G C T T G G T A G G T A C C T T G G T A C C A A G C T T G C T A G C T A G G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T G G A A C G A A G G T A G C T T G G A T G G T T C G A T C C T A G C T A G G T A C G T T G C A A G C T A G C A A G C T A C C T T C C T T C C A T G C A A G C A T G G A A C C A T G G A A G G T T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C C T A C G A T C G A A G C T T G C A A G G T A C C T T G C T A C G A A G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C G T T G C T T C G A T C C T T G G A A C G A A G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A C C A A G G T A C C A T G G A T G G T A G G A T G C T A C G A T C C T T C G T A C C T T C G A A C G A T G C A T G G T T G G A A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C C A T C C T T C G A A G C A A G C T A G C T A G C T A C C T T G C T A C G A T G C A A G G T T G G A T G G A A G G A A G C A T G G T T G G A T C G A T G G A T C C T T C C T A C G T T G G T A C C T A G C A T C C T T G C T T G C T A C G T A G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A G C A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G A T G C T T C C A A C C T T G C T A G G A A C C A A C C T T G C T T C G T A G C A T G C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +104 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T C G T T G G T T G G A A G C A T G G T A C C T A G C T A G C A T C G A A C G T T G C A A G C T T C C T A G G T A G C T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C A A G G A T C G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A C C T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C G A T C G T A G G T A G C A A G C A A G G T A G G T A C G A T C C A T C C T A G C T T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G C A A G G T T C G A T G G T T G G T A C C A A G C T A C G A T G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A C C A A C G A A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T T G C T T C G A T C C T A G C T A G C A T G C T T G C A A C C T A C C A T G G T A G C A T C G T T C C T T G C A A G C A T G G T A C C A T G G A A G G A A G C A T G C T T C C A A G C T T G C T T G C T T C G A A G C A A C C T T C C T T C G A T G G T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A T C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T C C A A G C A T G C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T A G C T T G G A T G C T T G C A T G G A A C C T A G G T A C C T A G G T A C G T T C C T A G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C A T G C A A C C A T G C A T C C T T G G T T G G T A C G A T G C T T G G A A C C A A G G T A C G T T G C T T C C A A G C A T G C T A G C A A G G T T G G T T G C A T G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C G A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A C C A T G C T T C G T A C G A A G G T T G C T A C G A T G C T T G G A A G C A A C C T A G C T A C C A T C C T T C C A T C G T T G C A A G C T T G G T T G C T T G C T A C C T A G C A T C C T A G G A A C C T A G G T A G G T A G C T A G C A +105 A C G T A C G T A C G T A G C A A G G T T G C T A G G A A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T A C C T T G G T A G C T T G G T T G C A T G G A A C G A A G G T T G G A A G C A T C G T A C C A A G G A A G C T T G G A T C G T A G C A A G C T T C C T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C C A T G G T T G G A T G G A T C G T T C G T A G C T T G C A A G C A A G G A T G C A A C C T A G G A A C C T T C C T A G C T A G C T A C C T T G G T A G C A T C C A T G C T A C G T A G C T T G G A A C G A A G G T T C C T A C C A A G G T T G G A T G C T T C C T T G G A A C C A T G C T A C G A A C G T T G G T A C G T T C G T A G G A T G C A A C C T A G G A T C G T A C G A T G C A A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A T C C A A G G T A C C T T G G T A C C T A G G T T G C T A G C T A C C T T G G A T G C A A G C T T C G A T G C A A G G T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C A T G C A A G C A A G C A A G C A A G G T A G G A T G C T A G C A T G G A T C C T A C G A A G G T A G C T T C G T T G C A T G G A T G C T A C C T A G C A A C G T T C G T A G G T A G C T A G C A T C C A T C C T T G G A T G C T A G G A A G C A A G C A T C G A T G G A T C G A T G C A A C C A A G C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T G G T A C C T T G C T A C G A A G G T A C C T T C C T A G G T A C C A T G G T T C G A T G C A T G C T T G C A T C G A A G C A T G C T T C C A A C G A T G C T A G C T A C G A A C C A T G C T A C G A A C C T A C G A A C G A A G C T T C G A T C C T A G C A T G G T T G C A A G G A T C C T T C C T T G C A A C C T T G C A T C C A T C G T A C C A T G G T A C C A A G G T T C C T A G C A T G G A A C G T A G G A T C G T A G G A T C C T T C G T A C C T A G G A T G C T A C C T A C G A A C G T T G G A T G G T T G C T T C G A A C G T A C G T A G G A T G C T A C C T T C C T T G C A T C C T A C C A T G C T T G C T T G G A A C G T T G G T T C C A A C C A T C G T T G G A A G C T T C C A A G C A A C C T A G G T A C C A T C G T T C C T A G C A T G G T A G C A T G C A A C C T T G G T A G G A A C G T T C C T T C C T A G C A T C C A A C C T T G C T A G G A T G C T T G C T A C C T A G C T A G G T T C G T T C C T A G C T T G C A A G C T T G C A A G G A A C C T T C G T T C G T T G C T T C C T A C C A A C C A T G C A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C T A G C T A C C A T G C T T G G A A G C A T C C A T C C T T C G A A G C T T G C T T C G T T C C T A G C T T G C T T C C T A C C A A C G T A G C T A C C A A G C A T G C T A G G T A G G A A G G T A C C T +106 A G G A A C G T A C C T T G C A T G C T T G C T A G G T A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T T G C T T G C T A G C T T G G T A G C A T C G A T G G T T C G T T G G T A C C A T C G T A C C A A C G A A G C A T G C A A C G T T G C A A C C T T C C A A G G T T G G T T G C A T C C A A G C T T C C A T G C A T C G A T G G T A G C T A G C A T C G T T C G T A G C T T G C T A G G A A G G T A C C T A C C T A C G A A C G T T C C T T G C T A G C T A G G T T G C T A G C T T C C A T G C T A C G T A G C T A C G A A C G T A G G T A C C A A C G A T G C T A C G A A G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C G A A G C T A C C A A G C T A G G T A C G T A C G A T G C T A C C T T C C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A T G C A T G C T A C C A T G G T A C C T T G G A T C C T A G C A T C C T T G G A A G G T A C G T T G G A A C C T A G G T A G G A A C C A T C G A A G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C T A G G A A G G A A G G T T C G A A G G A A G G T T C C A A C C A A G G T A C C T T G G T A C C A A G C T T G C T T G C T A G C A T C C T A G C T T G C A T G C A T C C T A C G T T C C T T G G A T G G T A G C A A G G A A C C T A C G A A G C T A G C A T C G T A C C T A C C T T G C T T G G T T C G A T C G T T C C T A C G T T G G A A G C A T G C A A G C A A C C T A G C T A C G A A C C A A C G T A G G A A G C T A C C A A G C T T G C T T G C T A G C T T C G A A G C A A G C T A C G T T C C A A C G A A G C T T C C T A G C A A G C A A G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A A C C T A G G A T C C T T G C T T G C A T C C A T G G T A C G T A G G T A C C A A G C A A G C T T G G A T C C T A C G T T G G T T C G T A C G A T C G T T G G T A C C A A C G T A C G A T G C T T G C A A G G A T G C A A G G T T G C T A G G T A C G T T C C T A G C T A G C A T G G A A C C A A G C A A G G T T C G A T G C T A G G T A G C T A C C T A C G T A C C A T C C A T G G A A G C A A G C T A G C A A G C T T G C T T G G T A C C A A C G A A G G T T G C A T G G A A G G A A G G A T G G T T G C A A G C A A C C A T C C T T C C T A C G T A G C A T G C T T G G T T G G T A G C A A G C T T C C A A G G T A C G T T C C T A G C T A C C A T G C T A G C T T G G A A G C A A G G A A C C A T C G T T G C A A C C T A C G A T G C A T C G A T C G A A G C A T G C A T G C A A C G A A G G A T C G A A C G T T C C A A C C T A G C T T G C T T G C A A C C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C C T A G G T A C C T A G C T A C G T A G G T A G G A A G G T A C C T +107 A C G T A C G T A C G T A G C A A G G T T C C T A G G T A C G A A C C A A G G A T G C T T G C T A C G T T C G A T C C T T G G T A G C A T C G A T C C T A C C T T G C T A G C T T G C T T G G A T C C T T C G T A G C A T C G T A C C A A C G A A G C T T G G A T C G T A G C A A G C T T C C T A G G T T G G T T G C A T C C A A G C T T C C A T G C A T C C A T G G T A G C T A G C A T C G T T C G T A G C T T G C T A G G A A G G T A C C T A G C T A C G A A C G T T C C A A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T C C T T G C A T G G T A G G T A C C A A C C A A G G T A G G T T G C T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C C A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A C C T T G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A T G C A T G C T A C C A T G G T A C C T T C C A T G C T A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G G A T G C T A G C A A G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A A G G A A C C A A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C A A C G T T G C A T G G A T C C T A C C T A G G T A C C T A G G A A G G A A G G A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A G G T T C C A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C G T T C C A T C C A T G G A T G C T A G C A A G G T T C G A T C C T A C G A A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A A G G A A G C T T C C T T G C A A C G A A G G T A C C A A C G T A G C A A C C T A C G T T C C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C A T G G A A C G T A G G T A C C A A G G T T C C T A C G A T C C T A C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G C T A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C C T A C C A A C C T T G C T A G C T T G G T T G G T A C C A T C C A T C G A A G C A A G C T A G C A A C C T T G G T A G G A A C C A T C G T T C G T T G C A T G G A A G G A A G G A T G G T T G G T A C G A A C C T T C C T T C C T A G C A T C C A T G C T T G G T T G G A A G C A A G C T T C C A A G G T A C G T T C C T A C C T A G C A T G C T A G C T T G C A A G C A A G G A T C G T T C G T T G C T T C C A A C C T A C C A T G C A T C G A A G C A T G C A T G C A A G G A A G G A T C G A A C G T T C C A A C C T A G C T T G C T T G C A A C C A T C C A T C C T T C G A A G C A T G C T T C G T T C C T A G G T T G C T T G C T A G C A A C C T A G G T A C C T A G C T A C G T A G G T A G G A A G G T A C C T +108 A C C T A G G T A C G T T G C T A G C A T C C T A G G T T G G T A C C A A G G A T C C T T G C T T G G A A C G A A C C T A G G T A G C A T G C T T G C T T G C A T G G T A G C T T C C A T G G T T G G T T G C T A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C G T A G G T T G G T A G C T T G C A A G C A A G G A A G C A A C C T A C G A A C G T T C C T T G C T A G C T A G G T T G C T A G C T T C C A T G C T A C G T A G C T T G G A A C G A A G G T T C C T A C C A A G G T T G G A T G C T T C C T T G G A A C C A T C C T A C G A A C G T T G G T A C G A A C G A A G G A T G C A A C C T T G G T T C G A A C G A T C C A A C G T A C C T T C G A A G G A T C C A T C C T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C G T A C G T T G G A T C C T A G C A T C C A A C G T A G G T A C G A T G G A A G C A A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G G T T G C T A C G A A G G T A G C A A C G T A G C A T G G A T C C T T C C T A G G T A C G T A G G A T G G T A C C A T G G T A G C T T C C T A C G T T C G A A G C A T G G T T C C A T G C A T G G T T C C A T C G A A G C A A G C T T C C T T G C T T C G A T G G A A C C T A C C A T C G A A G C A T G G A A G G T A G C T T G C T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A G G T A C C A A C C T T C C T T C C T A G C T A C G T T G C T T G C A A C C T A G G A T G G T T C G A A G G A T C C T T C C T T G C A A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A T G G T A G G T A G C A A C G A T C G A T G G A T G C T T G G T A C G T T G C T T G G A T G G A T G C A T G G T A G G A T G G T A C G T T G G A T G C T A G C A T G G T A C C T T C G A T C G A A C G A T C C T A G G T A G C T T G G T T G G T A C C A T C C T T C G T A G G A A G G T A G C T A G C T T G C T T G C A A G C A T G C A T G G T T G C A A G G A A G G A A G G A T G G T T G C A A G C A A C C A T C C T T C C T A C G T A C G A A G G T T G C T A G G T A G G A T G C A A C G T T C C A A G C T T G C T A G C A A G C T T C G T A G C A T G C A A G G A A C C T A C C T T C G T T G C T T C C T A C C A A C C A T C C A T C G A T G C T T G G A T G C T A C C A A G C T T C G A A C G A A G C T T G C A A C C A T G C T T G G A A G G A A C C T T C C T A C C A A C C T T G C T T G G T T G C A A G C T T G C T T G C T A G C T A C C T A G G T A G G T A C C T A G C T A G C T A G C A A C G T A C C T +109 A C C T A G G T T C G T A G C T A C C T T G C A A G G T T G C T T C C T A C G A T C C T T G C T T G C T T C G A T C G T A C C A T G C A A C C T T G C T T G C T A G G T A G C A T C C A T G G A T G G T T G C T T C C T T G C T A C C A A C G T A C G A T G C T T C C A T G C A A C C A A C G A A G C T T G G T T G C A T C C A A G C T T C C A T C C A T C C A T G G T A G C T A C G A A G C T T C G A T G C A A G G A A C C T A G G T T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G A T C C T A G G T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G T T G G T T G G A T G C T T C C T T G C A A C G A T C C T A C G A A C G T A G G T A G G A A C G A A C C T A C C A A G C T T G G T A C G A A C G A T C C A T C G T A G C T T C G T A C G T A G C A A G G T T G G A T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C C A A G G A T G G A T G C A A G C T A G C T A G G T T C G A T C C A A C C A T C G T A C C A T G G T A C G T T G C A T C G A A G G T A G C A A C C A T C G T A C C T T G G A A G C A A G G T A G G T T C C T A C G T A G G A A G G A A G G T T C G A T C G T A C G T T G G A T C G T T G C A A C G T T G G A T C C T T C C A T C C T T G C A T C C A A G C T T C G T T C C A A C G A T C G A A C C A A G C T A C C A A C C A T G G T T C C T A C C T A G G A A G C T T G G T A G G T T C C A T G C T A C G T A G G T A C G T A C C A A G C T A C C T T G C A T G C A T C G T T C G T T G C A A G C A T G G A A G C T A C G A T C G A T G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T T C C T A C C A A G G T A G C A T C C T T G C T T C C T A C C T T G C A T C G A A G C A T C C A T G G T A C G A A G C A T C C T T C G T A G C A A G C T A G G A A G G A A C G T A C C A T G C A T C G A T C C T A C G A T C G A A G C T A C G A A C C A A G G A T G C T T C C A A G C A T C C A T G G A A G G T T G G T A C C A A G G T T C G T A C G A T G G A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A G G A T G G T T G G T T G G T T G C T A G G T A G G A T G G T A C G T T C G A T G C T A G C A A G G A A C C T T G G A T C G A A C G T A C C T A G G T A G C T T C G T A C G T A C C A T G G T T C G T A G C T T G C T T C C A A G C T T C C T T G G T A C C A A C G A A G G T T G C A T G C T T G C A A G C A A C G T T G G A A G G A A C G T T C G T T G C A A G G T A G C A T G C T A C C T A G G A T G C A T G C A T C C A A G G T A G G T T G G A A C C T T G C A T G G A A G C T T G C A A G G A A G C T T C C A T C G T T G C T A C C T A C C A A G C A T C C A T G G A T C C T A G G A T G C A T G C A T G G A T C C T A C G T A G G A T G C T A C C T A G C A T G C A A C C A T C C T A G C T T C C A A C C T T G C T A C G T T C C T A G C T T G C T T C C T A C C A T C G T A G G T A G C T A G C T A C G T A G G T A G G A A G G T A C C T +110 A G C T A C G T A C C T A G G T A C G A T G G A T G C T A C G T A C C T A G G T T G C T T G C A A G G A T C G A T C G T A G G T A G C A T C C A T G G T T G C A T G G T A G C A T C C A T C G A A G C T T G C T A C C A T G C T A C C A A C G A A G C T T G C A A C G T T G C A A C C T T C G A T G G A T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A C C T A G C T T G G T A G C A T G C A A G C A A C G T T G C A A G C T A G C A A C C T T G C A T G C T T G C A A G G T T G C T A G C T T C C A T G G T A C C A T C C A T G G A A C G A A G G T T C C A T G G A T C G T A G G A T C C T T G C T T G C A T C C A T G C A A C C T A C G T A C G T A G C T A C C A A G G A T C C T A C G T A G C T A G G T T G G A T C C T A C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T T G C A T C C T T G G A A G G T A C G T T G C A A C C T A G G T A C G T A G C A A G G T A G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G G A T G G A A C G T A G C T A G C A A G C T A C C T T G C A T G G T T G G A A C C T A C G T A G C A A C G T T G C T T C G A T G C T T C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G A T G C A A G G A A G G A T C C T A C G A T C C T T G C T T C G A A G C A A G C T A G C A A C C T T G G T T G C T A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G C T T C G A T C C A A G G A A C C T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A C G T A G C A A C C T A C G T T C G A A G C T A G G T T G C T T G C A T G C T A G G A T G G A A G C T A G C A A C G T T C C A A C G T T G C T T G C A T C C A T G G T T C G T A G G T A G C A A C C A A G G T A G C A T G G A T C G T A G G T A G C A A C G A T C G A T C G A T C C T A C G A A C G A T G C T T G G A T G G A A C C T A G G T A G C T A G C T A C G T A C C T A C G A A G C A A C C T A C C A T G C A A G C A T C C A A C C T T G C T T G C A T G G A T G G T A G C A T C G T T C C T T G G A A G G A A C C T A G C T T G G T A G G T A C C A A C C T T G G T T G G A T G G A A G G A T G C T A G G A T C G T A C G T A C C T T C C T T C C T A G G T A C G A A G G T T G C T T G G A A G C A T G C A A G G T T C C A A G C T T C C T A C G A A G C T T C G T A G C A T C C A A G G A A C G A T C G T T C G A T G C T A G C T A C C T A G C A T C G A T C G A A G C A A G C A T G C T A C C A T G C T A G C T A C G T A G C T T G C A A C C T T G C T T G G T A G G A T C G A T G C A A C C A T C G T T G C A T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C G A A G C A T G C A A C C A A C G T +111 A G G A A C G T A C G T A G C T A C C T T C G A A G G A A G C T A C G A A G G T T C C T T G C T T G G T T C G A T C C A T G G T A G C A T C G A T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G G A A C G A A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G C T A G C T T G C T A C C T A G G A T G C T A C C T A G C T T G G A A C G A A G C T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T C C T A C G A A C G T A G G T A G G A A C G A A C C T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C C A A G G A A C C A A G G T T C C A A C C A T G G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T T G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C T T G C T A G G A A G C T T C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +112 A G G A A C G T A C G T A G C T A C C T T C G A A G G A A G C T A C G A A G G T T C C T T G C T T G G T T C G A T C C T T G G T A G C A T C G A T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G G A A C G A A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G C T A G C T T G C T A C C T A G G A T G C T A C C T A G C T T G G A A C G A A G C T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T C C T A C G A A C G T A G G T A G G A A C G A A C C T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C C A A G G A A C C A A G G T T C C A A C C A T G G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C A T G C T T G G A A C C T A C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +113 T G G T T G G A T G C T T C C T A C C T T C C A A G G A A C C A A C G A A G G T T G C T T G C T T G G T T C G A T C C T A G G T A G C A T G C A T G C T A C C T T G C T A G C A A G C A T G G A A G G T T G G A A G C A T C G T A C C A A G G T A C G A T G C A A C G T T G C T A G C T T C G A A G G A T G C A T C C A T G C A A C C T T C C A T C C T T C C A T G G A A G G A A G C T A G C T T G G T A G C A T G C A A G C A A G G T T G C T A C C T A C C A A C G T T C C T T G C T T G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C C T A C C T A G G A A G C T A G G A A C G T A C G A T G G A T C C T A G G T T C G A A G G T A G G A A C G T T C G A T C G T T G C T T G C A T G G T T G C T T C C T A G G A A C C A A G G A T C C T A G G A A G G A A C C T A G C T A G G A A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T T C C T A G C A A G C A T C G T A C C T T G G T A C C T T G G T A C G T A G C A T C G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C T T C G A A C G A A C C A A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T C G T T G C A T G G A T C C T T G C T A G G T A C G T A G C A A G G T A C C T T G G T T C C A T C G T A G G A A C C T A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A A C C T T G G A A G C A T C G A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A A G C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C G A A C C A T G G T A C G T A G G T T G C A A C C T T C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C G A T C C A T C G A T G C A A G C T T C C A A G C T T G C T T G G T A C C A A C G T T C C T T G C A T G G T A G G T T C C T A C G T T G G T A C G T A C C T T C C T T G C A A G G T A C G A T G C T A G C A T G G A T G C T T C G T T C C T A G C T A G G T T C G T A G G T A C C T T C G T A G C A T G C A A G G A A G C T A C C A T C C T T G C T A C C A T C C T A C G A T C G A T C C A T C C A T C G A T C G T A G G A T G G T T C G A A C G T A G G A T G C T A C C A T G C T T G G A A G G A T C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C T T G G T T C C A A G C A A C C T A G G T A G C A A G C A A C G A A G C T A C C A A G G T A C C T +114 T C C A A C G T A C C T A G G A T G G A A G C T A G G T A C G T A G C A A G G T T C C T T G C A A G G T T C G T A G C T A G G T A G C A T C C T T G C T T G C T T G G T A G C A A C G A T C G T T C G T T G C T A C C T T G C T A C C A A C G A A G C T T G C A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T G C T A G C A A G G A T G G T T C C T T G G A T G C T A C C A T C G T T C G T A G C T T G C A A G C A A G G A T G C T A G C T A G C T A C C T T G C T A G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T C G A T G G T A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T T G G A A G C T T C G A A G G T A C C A A G C A T G G A A C G A A C G A T G C A A C G T A G G T A C C A A G G T T C C T T C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T C G A A C C T A G C T A G G A A G G A A G C A A G C A T G G A A C C A T G C A A C G T T G C A T G C A A G G T A G C T T G C A A G G T A G C T A G G A A G C T T G G A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A G G T A G G A A G C A T G G A T G C T T C C T A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T A G C A A G C T T G C A A G C A A C C A T G C T A C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C A T C G A A C C T A C G A A G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A C C T A C G A T C C T A G G A T G C T T G G A A C C T T C G T A G C T A C G T A G C T T G C T A G C T T G G A T G C A T C C T T G C T T G G T A C G T T G G A T G C T A G C T T G G A A C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G T T G G T A C C A T C C T T C G A T G C T T G C T A G C T A G C T T G G T A G G A A C C A A G C A A G G T T C C A T G G A A G G A T G C T T G G A T G G T A G G A A C G T T G C T T G C A A C G T T G G A A C C T A G C A T C C T T G G A T G C T A C G T A G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A A C C T A C C A T C G T T G C T T C C T T C C A A C G A T C G A T C G A T G C A T C G T T G C T A G C A T G C T A G C T A G G T A G G A T G C T A C C T T G C T A G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G G T T C C T T G C T A G C A A C G T A G C A T G G A A G G A T C C T A G C T A G C A A C G T A C C T +115 A C G T A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C G T A G G T T G C T T C C T T G G T T C G A T G C A A G G T A G C A T G C A T C C T A C C T T G G T A G C T T C C T T G G A T G G T T G G T A G C A T C G T A C C A A G G A A G G A T G G A T C G T T G C A A C C T T C G A T G G T T G G T T G C A T C C A A G C T T C C A T G C A T C G A T G G T A G C T A G C A A G C T A C C A A G G A A G G A A G C A T C G A A G G A T C C A A C G A T G C A T C C A A G G T A G C T A G G T T C C T A C C T T C C A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C C T T G G T T G G A A G C T T G C T A G G A A C C T T C C A T C C A A G C T A C G A A G C T A C G T A G G T T G G A A C G T T G G A A C G A A C G A T G C A A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G C A A C C T A G G T A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T T G C A A C C A A G G A A G G T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T A G C T T G G A T G C T T G C T A G G T A C G T A G G A A G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T A C C T A C G T A G C A A C C T A C G T T C G A A G C T A C C T T G C T A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A T G C T T G G T T G G A T G C A T G G T T G C T A G G T A C G T T C C T A G C T A G C T T C G A A C C A A G C A T C C T A C C A A C C T A C G T T G C A A G G T T G C T T G C A T C C T T C G A T G C A A G C T A G C A A G C T T C C T T G C A A C C A T G C A A G C A A G C A T G C T T G C A A C C A A C G A T C G T A C G A A C C T T G C T T G C A A G G T A G C T A G C A T C C T T G G A T G C A A G C A A C G T T G G T T C G T T C C T A G G T T G C T A G G A A G C A T G C A A G G A A G C T A C C A T C G T T G C A A G C T A C G A T G G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C C T T C G T A G G T A C C A A G C A T G C T T G G A A G C A A C C T A G C T A C G A A G C T T G C T T C C T T G C A A G C T T G C T T C C T A C C A A C G T A G C A A C C A A G C A A C G T A G G T A G G T A G C T A C G T +116 A G C T A G G T T C G T A G C T A C C T T G C A A G G T A C C T A C C A A G G A T G C T T G C T A G G A A G G A A G C T T G G T A G C T A G G A T G C A A C C T T G C T A G C A T G C T T G G A T C C T T G G T A G C A T G C T A G C A A G G T A C G A T G C T T C G A T G C T A G C A T C C A A G C T T G G T A C C A T C C A A G C A T C C A A C G T T C C A T G G T A G G A T G C A T C G T T C G T A G C T A G C A A C G A T C G A A G C T A G C T A G G A A C G A T G G A T G C T A C G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T G G A T G G T A G G T T G G T T G C T T G C A A C C A T G C A A C C A A C G T T C G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G T T G G T T C G T A C G A A C G A A G C T T G C A T G G T T C G T T C G T T C G A A C C A A G G A T C C T T G G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G G A T C C T A G C A T C C T T G G A A G G T A C G A T G G A A G G T A G G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A A C G T A G G T T G G A A G C A T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T C G A A C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G C A A G G A T G C T A C G A T C C T T C G A T G G A A G C T A C C T A G G T T C C T T G G A A C C A T G C A A G G T T G G T T G G A A G G A A G G A A C C T T G G A T C G A A C C T T C C T T G C A A C G T T G C T A G C A A C G A T G C T A G C A A C G T T C C T T G G T T C G T T C C T A G G T T G C T A C G A A G C A T G C A A G G A T G C T A C C A T C G T T C C T A G C A A C C T A G C A T C G A A G G A T C C T A G G A T G C A A C C A T G G A T C C T A C G A T G C T T G C T A C G A T G C T T G G A A C C A T C C T A G C A A C C A A C C T T G C T A C C T T G G T A G C T T G C T T C C A A G C T A C C T A G C T A C C A A G C A T G C A T G G T A G G A T G C T A G G T +117 T G C A A G G A T C G T T C C T A C C T T C G A A G G A A C C A A C C A A G G A T C C T T G C A T G G A A C G A A C C T T G G T A G C T T G C A T C C A A C C T T G G T A G C T T C C T T G G A T C C T T G G T A G C A T C G T A C C A A C G T A C G A T G C T T C G T T G C A A C C T T C G A A G G T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A A G G A A G G A A G C T A C C A A G G A A G C A A C C A T C G A A G G A T C C A A C G A T G C T T G G A A G G T T G G T A G G T T G G T T G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T G G A T G G T A G G T T G G T T G C T T G C A A C C A T G C A A C C A A C G T T C G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G C T A C G T T C C T A G C A A C G T T G G T A G C A T G C A A G C T T G G A A C C A T C G A T G C T A C G A A C C A A G C A T G C A T C G A A G C A T C G T T G C A A G G A T G G A A C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A T G G A A C G A A C C T A G G T A G G A A G C T A G C T +118 A G C T A G G T T C G T A G C T A C C T T G C A A G G T A C G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A G C T T C C A T C C T A C C T A G G T A G C A T C C A T G G T T C G T T G G T A G C A T C C T A C G T A G G A A C C A T C G T T C G T T G C A A G C T T C G A T G G T A G G T T G C A T C C A A G C T T C C A T G C A T C C A T G G T A G C T A G C A A G C T T C G T A G G A T G C A A G C A A G G A T G C A A C C T A G C A A C G A T C C T T G C T A C G A A G G T T C C T A C C T T C C A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C C T T G G T T G G A A G C T T G C T A G G A A C C T T C C A T C C A A G C T A C G A A G C T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T T C G A T C C T T C G T T C C A A G G A A C G A A G C A A C C T T G G A A C C A T G C A A G C A A G C A A G G A A G G A T C G A A C C T T G G T A G C A A C C A T C C T T G C A T G C A T G C A A G C T T G C T T G C T A G G A A G C T T C C A T G G T T C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C C A A C C A A C C T T C C A T C C A T G C T T G G A T G C T A G C A T G C T A G C T A G G T A G C T T G C T A G C A T G C T T G G A A G C T A C C T A G C T A C C T A G G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +119 T G C T A C G T A C G T T G C T A C C T A G C T A G G T A G G T A C C A A G G A T G C T T G C T A C G A A C G A T G C T A G G T A G C A T C C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A G C T A G G A T G C A T G C A A C C T T G C A A C C T T C G A T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C G T T C C T A G G T T G G T A G G T T G G T T G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T C G A T G G T A G G A A G G T T G C T T G C A A C C A T G C A A C C A A C G T A C G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C A A G G A A C C T A G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C G T T G C A A G C A T G G T A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G G T A G C T T C C A T G C A T C G T A C G A A G C A A G C A T G G A A G G T A G C T T G C T A C G A T C C T T C C T A C C A A G G T A C C T T C C T A C C A T G C T A C C T T G C A T C G A T G C T T G C A T G G A T G G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A G C A T C C T T G C A A G C T A C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T A C G A A G C T T G G T T G G T T G G T A C C A T G G T A G C T T C G A A C C T T G G A T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C T T C G A T G C T T G C T A G C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T G G A A C C T A G C T T G G A T G C T T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G C T T G G A A C C A T C G A T G C T A C C A A C C A A G C A T G C A T C G A A G C A T C G T T G C A A G G A T G G A A C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +120 T G C T A C G T A C G T T G C T A C C T A G C T A G G T A G G T A C C A A G G A T G C T T G C T A C G A A C G A T G C T A G G T A G C A T C C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A G C T A G G A T G C A T G C A A C C T T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A A C C T T C C A T G G A A G G A A G G A A G C T T C G T A G G A T G C A A G C A A G G A T G C A T C C A A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A T G C A A C C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T T G G A A G C T A G C A A G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C G T T G C A A G C A T G G T A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G C A A G G A A G G T A G C T A G G A A C G A T C G A T G G A T G G A T G C T A G C A A G G T T C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G G A A C G A A G C T A C C T A C C A A G C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A A C C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G C T T C G A T G G T A C C A A G G T T C C T A G G A T G C A T C G T A G G A T G G T T G C A T C C T A C G A A G C T A C G T A G G T T G G T T G G T T G G T A C C A T G G T A G C T T C G A A C C T T G G A T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C T T C G A T G C T T G C T A G C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T G G A A C C T A G C T T G G A T G C T T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A G C A T G C T A G C T A G G T A G C T T G C T A G C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A T G G A A C G A A C C T A G G T A G G A A G C T A G C T +121 T G C T A C G T A C G T T G C T A C C T A G C T A G G T A G G T A C C A A G G A T G C T T G C T A C G A A G G A A G C T A G G T A G C A T G C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A G C T A G G A T G C A T G C A A C C A T G G A A C C T T C G T T G G T T G C T T G C A T C C T A G C A T C C A T C C T T C C A T G G A A G G A A C G A A C G T T C G T A C C T A G C A A G C T A G G T A G C T A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A G G T T G C T T G C A A G C A T C C T A C G A A C G T A G G T A C G A A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C A T G G A T G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T A G C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G T A C C T T G C T A C G T T G G T T G C T A G G T A G C T T G G T A C G A A C C T A C C T T C C T A C G T T C C A T G C A T G G T T G C A A C C T T G C T T C C T T G G A T G C T T C C A T C C A T C G A A G G A A G C T A G C A A G C T T C C T T G G T A C C A T C G T T C C T T G G A T G G A A G G A A G C A T G C T T G G T A G G A T G C T T C C T T C G T A G C A T G C T A G C T A G C T T C C T T G G A A G C T T C C T A G C T A G G T T C C T T G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C C T A C C A A C G A T C G A A G G A T C C T A G G A T G C A A G C A T G C T T C C T T C G T A G G T A C C A A G C A T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T T C C T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A G C A A C G T A C G T A G C T A G G T A G C A A C G T +122 A G C T T G G A T G G T T C C T A C C T A G C A A G G A A G G T A C C A A G G A T G C T T G C T T G G T T C G A T G C A A G G T A G C A T C C T T G C A A C C T T G C T A G C A T C C T T G G T A G G T T G G T A G C A T C C T A C C T A G G A A G C A T G C A A C G T T G C A A G C T T C C T T G G T T G G A T C C A T C C T A G C A A G G A T C C A T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A T C C A A C G A T G G A T C C T T G C T T G C A A G G T T G C T A G C T T G G A T G C T A C G T A G C T T G G A A C G A A G G T T C C A A C G A T G C T A G G A T G C A A C C T T G C A A G C A T G C T A C C A A G G T T G G A A G C A A C C T A C C A T G C A A G C T A G G A A C G T A C G A T G C T T C G T A G C T T C G T A C G T A G C A A G G T T G G A T C G A A G C T T G C A T G G T A G C T T C C T A G C A A G G A A G C A A G C A T G G T A G G A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T C C T A G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T T G G A A G C A T C G A A G C A A C C A T G C T A C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C A T C G A A C C T A C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A A C G T A G G T A G C A A C G A T C G A T C C T A C C T A G G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T G C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T A G G T A C C A T G G T A G C T A C C A A G G A A C C T A C C A T G G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A C C A A G C T T C C T A C G A T G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +123 A G G T T G G A T G C T T C C T A C C T T C G A A G G T T G G T A C C A A G G T T C C T A G C A A C G A A G G A A C C A T G G T A G C A T G C A T G C T A G C T T G G T T G C A T C G A T G G A A C G T T G G T A G C A T G C T A G C T A G G T A G G A T G G A T C G T T G C T A G C A T C C A A G C T T G G T T C C A T C C A A G C A T C C A T C C A T C G A T G G T A G C T A C G A A G C T T C G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A C G T T C C T A G C T A G C T A G C T T C G T A C C T T C C A T G C T A C G A T G C T T C C A A C G A A G G T A C C A T C G A T G G T A G G A A G G T T G C T T G C A A C C A T G C A A C C A A C G T A C G A T G C T T C G A A G C T A G G A A C G T A G G A T C G A A C G T T C C A A C C T A C C T A C G A A C G A T C C A A G G T T C G T A C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T T G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A G C T A G C T T G C T A G G A A G G A A C C T T G C A T G C A T C G T T C C T T G G T T G C A A C G T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C T A C G A A C C T A G C T A G C T T G C T A G G T A C C A A C G T A C G A T C G T T C C T T C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T T C C A T G C A A C G A A G C T A G G T A G G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T G C T T G C T T G C A T C C A T G G T T C G T A G G T A C G A A C C T T C C T A C G A T G C T T C G T A G G A T C G T A C G A T C G A T G G A T C C T A G G A A G G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T T C C A T C G T T C G A A G C A A G G T A G C T A G C T T C C T T C C A A C C A T G C T T G G T T G G A T G G T A G G A A G C A A C G T T G G T A G G A T C C T T C C T T G C A A C G T T G C T A G C T A G C T T G G T T G G T T G C T A C C T A G C T A G G T T C C T A G G T T G C T T G C A A G C T A G G A A G C A A G C T T C C T T C G T T G C T A C C T A C C A A C C A T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G T A C G T A G G A T G C T A C C A T G C T T G G A A G G A T C C T T G C T T C C A T C G T T G C T T G C T T C C T A G C A T C C T T C C T T G G A A C G T A C G T T G C T A G C A A G C A A G C T A G C A A C C T A G C T +124 A C G T A G G T A C G T T G C T A G C T A G C T A G G A A G C T A C G T A G G T T G C T T C C T T G G T T C G A T G C A A G G T A G C A A G G A T G C T A C C T T G C T A G C A T G C T T G G T T G G T T G G T A G C A T G C T A C C A A G G A A G C A T C C T T C G A T G C T A G C T T C C T T G C T T G C T T G C A T C G T A G C A A G G A A C G T T C C A T G G T A G G A T G C A T C G T T C G T A G C T A G G A A G G A T C G A A G C T A G C T A G G A A C G A T G C A A G G T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T T C C A A C G A T G C T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G A T C G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A T C G T A G C A A G C A A C G T A G G T A G C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C A A G G T A G C A T C C A A G G T A C G A T G G A A C C T T G G A A C G T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T A C C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T T G G A A C G T A G C A T C G A T G C T T G G A T G C T A C G T A G G T A C G T T G C A A G C A T G C A T C C A A C C T T C C T T C C A T G G T A C C A T G G A A G C T A C G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C C A T C C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C A T G C A A C G A T G G T T C C T A C G A A C C A T G C T A C G T T C C T A G C T A C G A A G C A T C G A A C C T A C G T A G G T T G C A T C G A A C C A A G G A T G C T T G C T T C C T T C C A T G G T T C G T A G G T A C G A A C C T T C C T A C G A T G C T T C G T A G G A T C G T A C G A T C G A T G G A T C C T A G G A A G G A T G C T T G C A A C G T A C G T A G G T A G G A T G G T A C G T T G G A T G C T A G C A A G G A A C C T T G C A A G G T T G C A T C C T A G G A A G C T A G G T A C G T A C C A T C C T T G G A T C G A A G G T A G C T A C C T T G C T A G C T A C C A T G C A A G G T T G C A T G G T A C G A T C C T A G C T T C G T A G G A A C G T T C G T T C C T A C G T T G C T A G C T A G C T T G G A T G C A A G C T T C C T A G C T A G G T T C G T T G C T A G G T A G G A A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C C A A C C T A C G T A C C A T C C A A G C A T C G T T G C A A G G A T G G A T C G T A C G A A G C T T C C T A C G A T G C A T G C A A G C A A C C T A G C T A C C A T C G T T C C T T C C T T C C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A G G T A G C A A C G T +125 A G G T A G G T A C G T T G C T A G C T A G C T A G C T A G C T A C C T A G G T T G C T T C C T T G G T T C G A T G C A A G G T A G C A A G G A T G C T A C C T T G G T T G C T A C G A T G G T A G G T T G C T A C C A T G G T A C G A A G G T T G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C A A G G T A C G T A G G T A C C T A G G T T C G A T C C A T C C T A G C T T C G A A G G A T C C A T C C T T G C T T C G A A G C T T G C A T G C A T G C T T C G T A G C A A G G A A G C A A G G A A G C A T C G A A C C T A C C A A G G A A G G A A G C T A G C A T G C T A G C A A C C A A C G T T G C T T C C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C T T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T C C T T G G T T G C A T G G A T C C T T G C T A G C T T G C T T G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C C A T G G A T G G T T C C A T C C A A G G A A C C T A G C T T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T C G T A C G T A C G A A G G T A C C T A C C T A C C A T G C T A G C T A G C A A G G A A G C T T C C T T G G A T G G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T G C T A G C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T T C C T A G G A T G G A T C C T A G G A T G C A A G G A T C C T T C G A A G C T A C G A A G C T T G C T T G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T A G G A A C C A T G G T T C C T A G G A T G G T A G G A A G C A T G G T T G G T T C G A T C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T T G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +126 A C C T A G G T A C G T T G C T A G C A T G C T A G C T A G C A A C G A A G G T A G G A T G C T T G G T T G G A T G C T T G G T A G C T A C C T T G C T T G C A T G G T A G C T T C C A T G G T T C C T A G C T A C C A T G C T A C C A A G G A A G C T T G G A A C G A T G C A A C C T T C C A A G G T T G G T T C C A A C C T A G C A T C C A T C G T T C C A T C G T A G G A A C G T A G G T T C G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G C T A C G T T G G T A G G T T G G A T G C T A C G T A G G T T G G A A G G T A G G T A C C A A C G A A G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G A A G G A A C G A A G G T A C C A A C G T A G G T A G G T A C G A T G C A A G C A T G C A A G G A A C G T A G C A A G G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G G A T G G T T C G A T G G A A C C T A C C T A G C T A C G T A G C A A G C A T G C A T G C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A A G G T A C G A T G G A A G G T A G G A A G C A A G C T A G G T T C C A T G G A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C T T G G T T G C T T C G A T C C T T G C T A G G T A C C T A G G T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T G C A T G G T A C G A T G G T A G G T A C G T A C C A T G C T A C G A A G C T A G G T A G C A T C C T T G C A A G C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G C T A C G A T G G T A C C A A G G T T C C T A G G A A C C A T C G T A G G A T G G T T G C A T C C T A C G A A G C T A C G A A G C T T G C T T G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T A G G A A C C A T G G T T C C T A G G A T G G T A G G A A G C A T G G T T G G T T C G A T C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T T G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +127 A G G A T G G A T G C T T G C T A C C T A G C T A C G T T G C T T C C A T C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G C A A C C T T G C T A G C A T C G A T G G T A C G T T C G T A C C A A C G T T C G T A G G A A G C A T G C A A C G T T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G G A A G G A T C G T A G C T T G G T A C C T A G C A A G C A A G G T A G C T A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T A G G T A C C T T C C A T G G A A C G A T G G A A C C A A C G A T C G T A G G A T C C T T G G T T G C A A C C A T C C A A C C T A G G A A C G T A G G A T C G A A G G T A G G T A G G T A C C T A G G T T C G A T C C A A C C T A G C T T C G T A C G T A G C A A G G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G C A A G G A A G C A T C G A A C C T A C C A A G G A A C G A A G C A A G C A T G C T A C C A T G G T A G G T T G G A A C C T T G C A T C C T T G G T A G G T A C G T T G G T A C G T T G G T A C G T A G C A A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T T G G A A G C A T C G A A G C A A C C A T G C T A C G A T C C T T C C T A C C A A G G T A C C T T C C T A C C A T G C T A G C T A G C A T C C A A G C T T C C A T G G A A C G A A G C T A C C T A C C A A G C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A A C C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G C T A C G A T G G T A C C A A G G T T C C T A G G A T G C A T C G T A G G A T G G T T G C A T C C T A C G A A G C T A C G T A G G T T G G T T G G T T G G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C T A C C T T C C T A G G A A C C A T G G T T C C T A G G A T G G T A G G A A G C A T G G T T G G A T C G A T G G T T C C T T C C T A G G T A C C T A C C T A G C T T G G A T G G A A G C T T C C T A G C T A G G T T C G T T G G T A C G A T G G A A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T C C T A G G A A G C T A C C T A G C T A C G T A G C T T C C T A C G T T G C A T G C T T G C T T G C T A G C A A C G T A G C A T G C A A G C A A C C T A G C T A G G A A G C T A G C T +128 T G C A A G G A T C G T T C C T A C C T T C G A A G G A A C C T A C C A A G G T T G C T T G C T T G G T T C G A T C C A T G G T A G C A T G C A A C C T A C C T T G G T A G C A T C C A T G G T T C C T T G C T A C C T T G C T A C G A A G G A A C C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A G C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C G T A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C T A G G T A C C A A C G T T G G A A G G T A C G A T G C A T C G T A G C A A G G A A G G T A G C A A G G T T G G A T C G A A G C T T G C A T G G T A G C T T C C T A G C A A G G A A G C A A G C A T G G T A G G A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T C C T A G G T A G C A A G C A T C G T A C C T T G G T A C G T A G G T A G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C A T G G A T G C A A C G T A G C T A G C A A G C T A C C T A G C A A G G T A C C T A C G A A G G T A G C T T G G T A G G A T G G A T C C T T G C T A G G T A C G T A G G A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A T C G A T G C A T C G A A G C A A C C T T G C A A G G A A G G T A G C T A G G A A C G A T C G A T G G A T G G A T G C T A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C A T C G A A C C T A C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T A C G A A G C T T G C T T G C A A C G T A C C A T G G T A G C T T C G A A C C T T G G A T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C T T C G A T G C T T G C T A G C A A G G T T C C T A G G A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A G G T T G G T A G G A A C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T A G G T A G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G A A G C A A G C A A C C T A C G A T C G A T C G A A G C T T G C T T G C A A G G A T G G A T C C T A C G A T G C T T G C T A C C A T G C T T G G A A G C T T C C T T G C T A C C A A C C A T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +129 T G C T A C G T A C G T A G C T A C C T A G C T T G G T A G C T A G C A A G G A T G C T T G C T A C G A T C C T T G C T A C C A T G C A T C C A A G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A G C T A G G A T G C A T G C A A C C T T G C A A C C T T C G T T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A T C C A A C G A T G G A T C C T T G C T T G C A A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A C C T A G C T T G C T A C C A T C C A T C C A A C G A A C G A T G C T T C G T A G G T A C C A A C G A A G G A A G G A A C G A T G C A T C G T A G C T T G G T T C G T A G G T T C G T T G G A T C G A A G C T T G C A T G G T T C C T T C G T A G G A T G G A A G G A T G G T A G G A A G G A A C C T A C C T A G G A A C G A A G C T T C C A T C G T A G C A T G C A A C G T T G G A T C C A T G C A T C C T T G G T A C G A T C C A T G G A A G C T A G G A T G C T T C C A T C G A T C C A T G G A A G C T A C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G T A G C A T C C A A C C A A C C A A C C A A C G A T G C T A G C A T C G T T C C T A C C T A G G A A G C T A C G T A C C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A C G A A G G A T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +130 A G G A A C G T A C C T T G C T A C C T A G C T A G G T T G G T A C C A A G G A T G C T T G C T A C G A A C G A T G C T A G G T A G C A T C C T T G C A A C C A T G G A T C G A T C G A T G G T T C G T T G C T A C G A T C C T T C C T A C C A T G G A T C C T T C C A T G C A A C C T T C G T A G G T T G C T A G C A T C C T A G C A A G G A T G C A T C G A T G G A A G C T A C C A A G C T T C G T A G G T A G G A A G C T A G G T T G C T A G C T T C G A A G C T A C C A A G C A A C G T A C G A T C C T A G C A A G G T A G G T T C C T T G C T A G C A A C G A A G G T T C C T A C G A A G G T A G G A T G C A A C C T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C G A A C C T A G C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A C G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C A T G G A T C C T T C G T A G G T A C G T A G G A A G G T A G C T A G G A T C C A A C C T T G G T T G G T T G C A A G C A A G C A T C G A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C G A T C G T T C C T T C G A T C C A T C C A T G G A A G C T T C C T T G G T T G C A T C C T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T G C A A G C T T C C T T G C A A C G A A G C A T C C A A C G A A C C A T G C T A C G A A G C A A G G T A G G A T G C A T C G A T C C T T C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A G C T T C C T A G G A T G G T T C G T A G G A T G C A A G G A T C C T T C G T A C C T A G G A A C G A T G C T T G G T T G G T T G C T A G G T T G C T A G G T A C G T T C C T A C C T A G C A A G G A A C C T T G C A T C G A A C G A T C C T T G G A A G C T A C G A T G C T T C C A T G G T T C G T A G C A A G C T A G C T T G C A A C G A T G C T A C G A T G C A A G G T T G G A T G G T A G G A T G C T A C C T T C G T A G G A T C C T T C C T T C C T A C G T T C G A A G C A A G G T T C G T T G C A A G C T A C C T A G G A A G G T T G G A A C C T T G C T T G C A A G G T A G C A A G G A A C C T T C G T T C G T T G C T T C C A A C C A A C G A T G G A T C C A T C C A T C C A T G C A T G C A A G C T T C C T A C C T T C C A A G G T A C C A A G C A T G C A A G C T T C C T A C C A A G C T A G C T T G G A T C G T T C G T A G G T T C C T T C C T A G C A A C G T A G C A A C C A A G C A A C G A A G C T A G G T A G C A A C C T +131 T G C T A C G T A C G T T G C T A C C T A G C T A G G T A G G T A C C A A G G A T G C T T G C T A C G A A C G A T G C T A G G T A G C A T C C T T G C T A C C T T G G T T G C A A C C A T G G T T C G T T G C A A G C A T G G T A G G T A G G A A C C A T G C T T C G T T G C A A C C T T C G A A G G T T C G T T C C A T C C A A G C A A C C A T G C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G C A A G G T A G C T A C G T A G C A A G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C G A T G G A T C C A T G G A T C G T A G G A T C C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C G A A C C T A G G A A C G T T G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T A C C T A G G T T C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C G A A G C A T C G T T G C T A G G A T G G A A C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T C C T A C G T T G C A A G C T T G C T T C C T A C C A A C G T A G C A A C C A A G C A T G C A T G G T A G G A A G C T A C G T +132 A G G T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A G C A A G G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A T C C A A C C T A C C T A G G T A G C T T G C T T G G A T C C T T G C T A C C A T G G T A C G A A G G A A C C A T G C A A C G T T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G G A A G G A T C G T A G C T T G G T A G C T A G C A A G C A A G G T A G C A A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T A G G T A C C T T C C A T G G A A C G A A G G T A C C A A C G A A G G T T G G A T G C T T G G T T G C A A C C A T C C A A C C T A G G T A G G T A G G A T C G A A G G T A G C A A G C T A G G A A C G T A C G A T G C T T C G T A G C T T C G T A C G T A G C A A G G T T G G A T C G A A G C T T G C A T G G T A G C T T C C T A G C A A G G A A G C A A G C A T G G T A G G A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C A T G G A T G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T G C A A C C T A G C T T G G A T G C T T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T T C C T T C C T A C G T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +133 A G C T A C G T A C C T T C C A A C C T T G C T A G C T T G G T A G C A A G G T T G C T T G C T T G G A A G G A A G C A A C C T A G C A T C C A A C C T T G C T T G G T T C C T A C G A T G G A A G G T T G C T A G G A T C C T A G C T A C G A T G G A T C C T A C C T T C C A A C C T A C C T A G C T T G C T T C C A T C C T A G C A A G G A T G C A T C C T T G G T T G C T A C C A A G C T T C G T A G C A T G G A T G C A A G G T A G C A A G C T A C G A A G G A T G C A A G C A A C G T A G G T T C C T A G G T T C C T T G G T A C C T T G C T A G C A A C C A A G G T T G C A A C G A A C G T T G G A T G C A A C G T T G G T A C C T T G G T T C G A A C G A A C G A T G C T T C G T A C C T A G G A A C G T T C C T T C G A A C G A T G C A A C G T T G G A A G C T A C G T A G C A A C C T A G G A T C G T T C C T T G C A T G G T A G C T T C C T A G C A A C C A A G G A T G C A T C G T T G G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T C C A T G C A A C G T T C C A T G C T T G G T A C C A A C G A T G G T A C G T T G C A A C G T A G G A A C G A A C C A A G G T T C C A T G G A A G G T T C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C C T T C G T A C G A A G C T T C G A A G C A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T G C T A C C T A G G A A G C T A C G T A C C T T G G A T C G T T G G T A G G T T C C T T G C A A G C T A C C A T G C T T G C T T C C T A C G A T G C A A G C A T G G T A C C A T G C A A G G A A G C A T C C A A G C A A C C T A C C T T C C T T C C A T C G T A C C T T C C A T G G A A G C A T G G A A G G T T C C A A G C T A C G A T C C A A C C T T G G T A G G T A C C A A G C T T G C T T G C A A G C T T G C A T C G A A G C T T C C T T G C A A C G A A G C T A G G T A G C A A C C A T G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T G G A T C G A T C C A A C C A A G G A A C C T T G C T A C G A T G G T T G C T A G G T A G C T A G G T A C G A T C G T A C G T A C C A A G C T A C C T T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T T C G A A G G T T G G A A C G A A G C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G T A C G A T C C T A G C T T C G T A G G A A C G T T C G T T C C A A G C A T C C T A G C T A G G T T C G T T G G T A G C T A C C T A G C T A G G T T C G T T C C T A G G A T G C T A G C T A G C A A C C A A G G A T C C T T C G A A G C T A C C T A C C T A G C A T C G A T C G A T G C A T G G A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C G T A G G T A G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G A A C C T T G C T A G C T A G C A A C G T A C C T +134 A C C T A G G T A C G T T G C T A G C A T G C T A G C T T C G A A C C A A C G A T G C T T G C T T G C T T G G A T G G T T G G T A C C T A C C T T G C T A G C A T G C T A C C T T G C A T G G T T G G T T G G T A G C A T C G T A C C A A C G A A G C A T G C A A C G T T G C A A C C T T C G T T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C A A G C T T C G T A G G T A G C A A G C A T G G A A G G A A C C A A G G A A C G T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G T T G C T A C C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C A A C C T A G G A T C G T A G C T T G G T A G G T A G C A A G C A T G G T A G G T A C C A T G G T T C C T A G C T T C G T T C G A A G G A A G G T T G C T A C G A A G C T T G C A T G G T T G G T T C G T T C G A A G G A A C C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A A G G T A C G A T G G T A G G T A G G A A G G A A C C A A G G T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G G A T G C A A G C A T C C T A C G A A C C A A G G T T C C T A G C A A G G A T C C T A C C T A G G A A G C A A C G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A T G C A T G C A T C G T A G G T T C C T T C C A A G G T A G G T T G C A A G C A T C G A T G G A T G C A T C C A A C C A A G C T A G C A A G G T T C G A A G C T T C G A T C G A T C G A T G C T T G C T A G G T A C C A A C C T A C G A A C G T T C C T A C C A A G G T A C C T T C C A A C C T A C C A A G C T A C C A T C G A A G C A T C C T T G G T A C G A T C G A T C C T A G G T A G C A A G C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T G C T A G C T T G C A T C C T A G G T A G C T A G G T A G C A A C C T A C C T A G G A T G G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A G G T T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C C A T C C T A G C A T G C A A G G A A C C A A G C A A C C T T C C A T C G A T G C A A G G T T G G T T C G A A G G A A G C T T G G T T G G A T C G T A C C T T C C T T G C A A C G T A G C T A G C A T G G T T G G A T C C A A G C A T C C A T G G T T C G T T C G T A C C T A G C T A C G T A G C A T G C A A G C A A G G A A C C T T C G T T G G T A C G A T C G A A G G A A C C A T C C A T G C T T G G A T G C T A C C A T G G A A G C T A C G T A G G A T G C T A C C T T G C A T G C A A G C A A C C A A C C T A C G A A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C A A C C A A G C T T G C A T G G A A C C T A G C A +135 A G C T A G G T T C G T A G C T A C C T T G C A A G G T T G G T T C C A A G G T T C C T T G C A A G G A T G G A A G C T T G G T A G C T T C C T T G C A A C C A T G G A T C C A T C C A T C G A A C G T T G G A A G C A T C G T T C G T A G C T T G C A T G C A A C G A T G C A A G C T T C G A T G G T A G G T T G C A T C C T A C C A A G G A A C C A T C C A T G G T A G C T A G C A T C G T T C G T A G C T T G C A A C C A A G G A T G C A A G C T A G C A A C C T T G C A A G C T A G G T A G G T T G C T A G C T T C C A A G G T A C C A T G C T T G G A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C T A C C A T G C T A C G A A C G T A C G A T G C T A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A G G T A G C A T G G T A C G T A G G A A G C T A G C T A C C T A G G T A C C A A G C T T C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T A G G A T G C A T C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T A G G A A G G T A G C A T G G A T G C T T C G A T C C T A G C T A G C T A C C T A G G A A G G A A C C T A G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T G C T A C G A A C G A A G C A A G C T T G C A A G G T A G C T T G C T A C G A A G C T T C C T A G C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A A G G A A G C T T C C A T G G T A C G A T G G T A G G T A G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A A G C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C C A T C G A T C G A A C G A A G C T A C C T T C C T T G G T A G C A A G C A T G C A A G C T T G G A T G G T A G G A A G C A A C G A T C G T T C G T A G C T T C C T T C C T A G G T A C G A A C C T A G C A T G G A T G C T T G C T A C G T A G C T T G G T T C G T T C C A A G C A T G C T A G C T A C C A A G G A A G G A T C G T T C G T T G C A A C C A T C G T A C G A T C C A T C G A A G C A A G G A T G C T A C G A T G G A T C G A A C G A T G G T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C T A G C T A G C A T C G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +136 A G G T A G G A T G C T A G G A T G C T A G C T A G G T A G C T T C C T A G G A T G C T T G C T T G G A A G G A A C G T T G G T A G C A T G C A A C C A A C C T T G G T A G C T T C C T T G G A T C C T T G G T A G C A T C G T A C C T A G G A A C C A T C C T T C G A T G C T A G C T T C G T A G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A C G A T G G T T C G T A G C A A G C A A C G A A G G T T G C T A G C T A G G A A C C A T G C A T G C T A G C T A C G T T C C T A G C T T C C A A G G T A G G A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A G C T T C G A A C G A T G C A A C G T A G G A T C G T A C G A T G C A A G C T T G C A A G C A A G G T T C C A T C G A T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C C T T G G A T G C T A G C T A G C A T C G A A G G T A C G A T G C A A C G T A G G A A G C T T C C A A G G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T C G T T G C A A G G T T G G T T G G A A G C T T C G T T G G T A C C A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T G G T T G C T T G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T A C G T T C G A A C G A A G C T A C C A T G C A T C G A T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T T G C A T C G A A G C A T C C T T G G A T C G A T G G T A C C T A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C T T C G A T C C T A C G A A C G T T G C T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C G T A C C T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C T A C G A T C C T T C G A T C C T A G G A A C G A T G C T A C C T A C G T T C C A T C C T T G C T A G G A A C G A A C C T T C C T A C C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C T T G G T T G C T A C C A T C C T A G C A A G G A A G C T A C C A T G C A A C G T A G C A A C G A T G C A A G C A A G C A T G G A A G G A A C C A A G C T T G G T A G G A T G G A T C C T T C C T A C G T A G C A T G G T T G C T T G G A A G G A T G C A A C G T T C C A A G C T T G C T A G G T A G C T T C G T A G C A T G C A A G G A A C C A A C C A T C G T T G G T A C G A A C C A A C G A T C C A T C C A T G C T T G G A T G C T A G G A T G G A T G C A A C G A T G C T T G C T A C C A T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C C T A G C A A G G T A C C T A G C T A G C T A G C A A C G T A C C T +137 A G C T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T C C T T G C A A G G A A G G A A G C T T G G T A G C A T G C A T C C A A C C T T G G T A G C T T G C T T G G A T C C T T G G T A G C A A G G T A C C A A G G T A C C A T G C T T C G A T G C T A G C T T C G A T G G T A G G T T G C A T C C T A C C T T C C A T C C A T C C A T G G T A G C T A G C T A G G T T G G T A G C T T G C A A G C T A G G A T G C T A G C T A C C A A C C A T G C T T G C T T G C T A C G T T C C T A G C T T C C A A G G T A C C A T G C T A C G A A C G A A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C G T A C G A T G C A A C G T A G G A T C G T A C G A T G C A A G C A T G C T T C G A A C G T T C C A T C G A T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C C T T G G A T G C T A G C T A G C A T C G A A G G T A C G A T G C A A G G T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T A C C T A G G A A G G A A C C T A G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T G C T A C G A A C G T A G C A A G C T T G C T A G C T A G C A A G G T T C G A T C C T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C C A A C C A A G C T T G G A A G G A A C G A A C C A T G C T T C G A A C C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T C C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A C C T T G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G T T G C T A C C A T C C A T C G A A C G A A G C T A C C A T C C T T G C T A G C T A C C A T G C A A G G T T G C A T G G A A G G A T C G A A G C A T C G T A G G A A G G A T C C T T G C T A C G T T G C A T G C T A G C A T G G A T G C T T G C T A C G T A G C T T G G T T C G T A C G T A G C T T G C T A G C T A G C A A G G A T G G A A C C A T C G T T G C A A C C A T C C T A C C A T C C A T C G A A G C A A G G A T G C A A C G T T G G A T C C T A C C A T C G A T G C T A C C T A G C A T C C A A G C T T C G A T C G A A C C A A C C T A G C T T C C T T C C T A G C T T G C T T G C T A G C A A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +138 A G G T A G G A T G C T A G G A T G C T A G C T A G G T A G C T T C C T A G G A T G C T T G C T T G G A A G G A T G C T T G G T A G C T A C C T T G C A A C C T T G G T T C C T T C C A T G G T T G G T T G G T A G C A T C G T A C C T A G G T A G C A T G G A T C G A T G C A A G C T T C G T T G C T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A A G C T A C G A T C G T T C G T A G C T T G C A A C C A A G G T T G C A A G C T A G C T A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C T A C C A T G C T A C G A A C G T A C G T A G C T T C G A A G G T A G G A A C C T A G G A A G G T A C G A T G C T A G C T T G C A A G C A A G G A T C C A T C G A T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G T A C G T A G G A A G G A A C C T A G G T A G G T A C C A A G C T T C G A T G G T A C C T T G C A T C G T T G C A A G G T A G G T T G C T T C C T T C G T T G G T T C C A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T G G T T G C T A G G A A G G T A G C A T G G A T G C T T C G A T C C T T G C T A G G T A C C T A C C T T C C T A C C T T G C A T G C A T C C T A C G T T G G A A C G A A G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C T T C G A A C G A T G G A A C C T T G G A A G G T A G C T T G C T A C G A A G C T T C C T A G C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A T C G A A G C A T C C T T G G A T C G A T G G T A C C T T G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A A G C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C C T T C C A T G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T T C G T T G C A A G G A A C C T T C G T A C C T T C G A A G G T T G C T A C G A T G G T A C C T A G G T T G C T T G G T A C G T T G G A T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A A G G A T G C T A C C A T C G A T G G A A G G A A G C T T C C A A G C T T G G T A G C A A G C A T G C A T G C T T G C A A G G T A G G A A G C A T G C A T G G T A G G A T G G A T C C T T C C T A C G T A G C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T T G G T A C G A T G C A A G C T A C C A A G G A A G C A T C C T T C G T T G C A A G C A A C G T A C G A T C C A T C G A T G C T T G G A T G C T A G G A T G G A T G C A A C G A T G G T T G C T A C C A T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C C T A G G T A G C A A G C A A C G A A G C T A C C A A G G T A C C T +139 A C C T T G G A T G G T T C C T A C C T A G C A A G G A A G G T A C C A A G G A T G C T T G C T T G G A A G G A A C C T T G G T A G C A T G C A A C G T A C C T A G C T A G C A T C G A T G G T A C G T T G G T A G C A T C G T A C G T A G G A T G G A T G C A A C G T T G C A A G C T T C C T T G G T T G G A T C C A T C C T A G C A A G G A A C C A T C C T T G G A T G C T A G C A T C G T T C C A A G G A A C C A A G C A A G C T T G C T A C C T A C G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T T G C T A C G A T G C T T G G A A G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C C T A C C T A C G T A C C A A C G T T C C T A G G T A C G A T G C T T C G T A G C T T C G A A G G T T C C A A C C T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C C T A G C A T C C T T G C A T C C A T G G A A C G T A C C T T G G T A C C T A G G T A G C A A G C A A G G A A G G T A C C A T C G A T C C A A G G T A C C T T G C T A C G T A G C A A G G A A G G T T G G A A G C T T C G T T G C T A C C A A G G A T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G C T A G G A A G G T T G C A T C G T T G C A T G G A T C C T A G C T A G C T T G C T A G C A A G C T A C C T T G C A T G C A T C G T T C C T T G C A A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A T C C T A C G A T C G T A G C A A G C T T G C T A G C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A T G G T A G G T A G G T A G C A T G C T T C G T A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T A C C T A C G A A G C T T G C T T G G A A G G A T G C A T C C T T G C T T G G T A C G T T G G A T G C T A G C A A G G T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T G G T T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T A C C T T G G A A C G A T G C A T G C A T G G A T G G T A G G A A G C A T G G T T G G A A G G T A C G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A A G C T T C G A A C C T T C G A A C C T A G G T A C G A T G G A A G C T A G C A A G G A A C C A A C G A T C G T T G G T A G C T A C G A T C G A T C C A T C C A T G C T T G G A T G C T A C C A T G G T A G C T A G G T A G G A A G C T A C C A T C C T T C G A A G G T A C C T A G C T A C C A A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +140 T G C T T G G A T G C T T C C T A C C T T C G A A G G T T G G T A C G A A G G T T G G T T G C T T G G T T C G A T G C T A G G T A G C A A G C A A G C T A C C T T G G T A G C A T G C A T G G A T C C T T G C T A C C A T C G T A C G T A G G T A G C A T G C T A C G A T G C T A G C T T C C T T G G T T G C T T C C A T C C T A G C T T C C A T C C A T C C A T G G T A G C T A G C T A G G T T G G T A G C T T G C T A C G A A G G T T G C T A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A T C C A T C C T A C G A T C G T T G G T A C G T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C T T G G A A C C T A C G T A G C A A C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A C C A T G C T T C C T T G G A T C C T A G G T A G C A T C C A A C G T A C C T T G G T A C C T A G C A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G C T A G G T T C G A T G C T A G C A T C G T T C C T A C C A A G G T T G C T T G G T A G C T T G G A T C C T A G C T A G C T A C C T A G G A A G G A A C C T T G C A T C C A T C C T T C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A A C C T A G C A A G C A T C C A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C A T C C A T G G A A C G A T G G T A C C T A C G T A G C A A C G T A C G T T C G A A G C T A G C T T G C T A G C A T G C T T C G T A G G T T C G T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T A C G T A G G A A C C A T C C T A C C T A C G A T G G A T C G T A G C A T C G T A C G A T C G A T G G A A G C T A C G T A G C T T G G T A C G T T G G A T G C A T G G T A G G A T G G A A C G T T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C G A A C C T A G G T A G C T A C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G C T T C C A T G C A A C G A T C C A A G G T T G G T T C G T A G G A T G C T A G C T T C G T A G G A A G G T T C C T T G C A A C G T T G C A A G C T A G C T T G G A T G G T T G C T A C G T A G C T A G G T T G G A A C C A A G G T A G C A A G C T T G C A A G G A A G C T T C C A T C G T T G C A A C G A A C C A A C G A T C C A T C C A T G C T T G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C T A C C A T G C T T G G A A G C A A C C T T C C T A C C T A C C T A G C A A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G C A A G C A A C G T A G G T A G G T A G C A A C G T +141 A G G T A G G A T G C T T C C T A C C T T G G A A G G A A C G T A G C A A G G T T C C T T G C A T G C A T C C T A C G T T G G T A G C A A C C T T G C T A C C A A G C T A G C A T G C A T C G T A G C T T G G T A G C T T G C T A C C A A G C A A C C A T G C T T C G A T G C A A G C A T C G A A G G T T G C T T G C A T C C A A G C A T C C A T C C T T G C A T G G T A G C A A G C T A G C T T C G T A C G T A G C A A C C A A G G A T G C T A G C T A C C A A G G T T C C T A G C A A C G T A G G T T G G T A G C T T C C A A G G T A G G T T G C T A C G A A C G A A G C T T C C A A C C A T G G T A G G A T G C T T G C T T G C A A C C A T G C A A C C A A G G T T C C T A G C T T C G A A G G T T G C A A C C T T G G T A G G T A C G A T C C A A C C A A G C T T C G A A G C T T G G A A C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G C T A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C T A G G T T G C A A G C A T G G T A G G A T G G A A G C T A C C A T G G T A C G T T G C T T G G T T G G A A G G T A G G T T G C T T C C T T C G T A G G T A C C A A G G T T C G T T C C A A C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A G G A A C G T A G C A T C G T T G C T T G G A T C C T T G G T A G G T A C G T A G G A A G G A A G C T T G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C A T G C T T C G A T C G T T C C T A C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G G A A C G A A G G T T C C T A C G T A G C A A G C T A G G A A C G A A G C T A C C T T G C T T C C A A C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T A G C A A G C T A C C A A C G A T C G T T G G T A G G A T G C A A G G A T C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T G G T T G C T A G G A A C G T T C C T A G C T A G C A A G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T G G T T C C A T C C T T C G A A G G A T G C T T C C T A G C T T G G T A G C T A C G A T G C A T G C A T G G A T G G T A G G A A G G A T G C A T G G T A G C A A C C A T C G T T C C T A C G T T G G T A C C T A G C A T C G T T G G A A G C T T C C T A C G T T C G T T C C T T G C T T C G A T C G T A G C T A G C A A G C A T C C T A G G T T C G A A C C A A C C T A C C T A C G T T C C A T C C A T C C T A G G T T C G A A G C A T G G A T G C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G G T A C C T T C C T T G G T T G C T T G C A A G C A T C C T A G C T A C C A A G C A T C C T A G G T A G G T A G C A A C G T +142 A C C T A G G T A C G T T G C T A G C T T C G A A G G T A G C T T C C T A G G A T G C T T G C A T G G A T G G A A C G T T G G T A G C T A C C T T G C A A C C T T G C T A G C A T C G A T G G T T C G T T G C T A G C A T C G T A C C T A G G A A C C A T G C T T C G A T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A T C C A T C G A A G G A T G G A A C G T T C G T T C G T A C C T T G C A A G C A A G G T T G C A A G C T A C C A A C G T T G C A A G C T A G G T A G G T T G G T A G C T T C C A T G C T A C C T A G C T T G G A A G G T A G G T T C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A C G T A G G T A G C A A C C T A G G T A C C A A G C T A G G A A C G T A C G A T G C T A G C A A C C A T C G A A G G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G A A G C T A G G A A G G A A C G A A G G T T C C A T G G A T C G T A C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C A A C G T T G C A T G G A T C C T A G C T A G C T T G C T A G C A A G C T A G C T T G C A T G C A T C C T T G G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C T A C G T A C C A T G C A T C G A A C C T A C G A A C G T T G C T A C G A A C C T A C C A T C C T T G C T A G C A T C C A T G G A A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G C A T G C A T G G T A G C T T C G T A C C T A G C T T G G A A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T C C A A G C T T C C T T G C A T G G T A C G A A C C T A C C T T G C A T G G T A C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T A C C T T G G A A C G A T G C A T G C A A G C A T C G A A G G A T C G A T G G A A C G T A G G A A C C T T C C T T G C A A G G T T G G T A G C A T C C T A G C T A G C A A G C T A C C T A G C T A G G T T C G T T C C T T G C T A G G A A G C A T G C A A G G A A C C T A C C A T C G T T G C T A C G A A C C T A G G A T C G A A G G A A G C T A G G A T G C A A C G T T C G A T C C T A C C A A G G T A G G T A G C A T G C T T G G A A G C T T G C T T C C A A G G T A G G T T G C A A C C T T C C T A G G A T G C T T C C A A G C T A C C T A G G T A G G T A G C A T C G T A G G T A G G T A G C T A C G T +143 A G C T T G G A T G C T T C C T A C C T T C G A A G G T T G G T A C G A A G G T T G C T T G C T T G G A A G G A A C C T T G G T A G C A A G C A A C C T T G C T A G G T A G C A A G C T T G G T A C G T T G G T A C C A T C C T A G G T A G G A T G G A T C G A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A G C T A G G T T G G T A G C A A G C A A C G A A G G A T G C T A G C T A G G A A C C T T G C A T G C T T G C T A G G T T G C T A G C T T C C A T G C T A C G T A G C T T G G A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T C C T T G C A A C G A T G C T A C G A A C G T A C G A T G C T A C C T A C G T A C C A A C G T T C C T A G G T A C C T T G C T T C G T A G C T T C G A A C G A A C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A G C A T G G T A C G T A G C A T C C T T C C T A G C A A C C A A C G T A C C T T G G T A C C T A G G T A G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G C T A G G T T C G A T G C T A G C A A G G T T G C T A G G A 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T C C T T G G A T G G T A G G A A C C T A C C T T C G T A C G A A C G T T C C T T G C A A C G A T G C T A C C T A G C T T C C T T G G T A G C T A C G T A G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A A G C A A C G A T C G T T G G T A G G A A C C A A C G T T C C A T C C A T G C T A G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C A A C C A T G C T T G G A A C C A T C C T T C C T T C G T A G G T T G C T A C G T T G C A A G G T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +144 A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G C A A C G A A G G T T G G T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C T A C C T A G C T A G C A T C G A T G G T T C G T T G G T A G C A T C G T A C C T A G G A A C C A T G C T T C G T T G C A A G C T T C G T A G G T A G G A T C C A T C C T A G C A A G G A T C C A T C C A T G G A T G C T A C G A T G G T T C G T A G G A T G C T A C G A A G G T T G C T A G C T A G C T A C C T T G C A A G G T A G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G C T T C C A A C G A A G G A A G G A T G C T T C C T T G C A T C C A T G C A A C C A A C G T T G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C T A C C T T C G A A G G T T C C A A C C A T G G T T C C T T C C T T G C A T G G T A G C T T C G T T C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T T G C A T C C A T C C A A G G T A C C T T G G A A G C A A G G A A G C A A G C A T C G A A G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T A C C A T C C T A C G T T G G T A G G A T G G A A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G T A C C A T C C A A G C A T G G A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G A A C G A T G G T A C C T A C G T A G C A A C G T A C G T T C G A T G G T A C C A T G C T T C G A T G C T T C G A T G G T T C G T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T T C G T A G G A A C C A T C C T T C C T A C G A T G G A T C G T A G C A T C G T A C G A T C G A T G G A A G C T A C G A A G C T T G C T T G G A T G G A T G C A T G G T A G G A T G G T A C G T T G G A T G C T A G C A A G G T T C C A T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C G T T C C A T C C A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T C C A A G G T T G G T T C G T A G G A T G C A T G C T T C G T A G G T A C G T T C C T T G C A A C G T T G C A A G C T A G C T T G G A T G C T T C G T T C 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A G G T T G C T T G C T T G C T T C C A T G C A A C C A A C G A T C C T A G C T A C C T A C G A T G C A A C C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C G T A G G T A G C A T G G A A G C T A G G A A G C A A G G A T C G A T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G G A T G C A A C G A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A T C G T A G C A T G G A T G C T A C C T A G G T A C G T A G C A A G C A A C C T T G C A T C C A T C C T T C G T T G C A A C C A T G C T A C C A T G G A A G G T T G C A T C C A A C C A A C C T T C C T T G C T T C G A T C G A A C C T T C G T A G G A A G C T T C G T A G C A A C C A T G C T T C G A T G G T A C C T T G C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A T C G A A G C A T C C T T G C A A C C A A G G T A C C T A C G T A G C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T A C G A T G G T T C C T A G C A A C C T A G G A T C C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G C A A G C T T G G A T G C T A C G T A G G T A G C A A C G A T C G A T G G A A G C T A C G A A G C T T G C T A C C T A G G T A C C A T G G T T G C T A G G A A C C A A C C T A G C T A G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C C T A C G T A C C A T C C T T G G A A G G A A G G T A G C T A C C T T G C A T G C A A C C A T G C A T C C T T C C A T G G T A G G A A G C A A C G T T C G T A C G A A C G T T G C T T C G T A C G T A C G T T G C T A G C A A C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C T A G C A A G G A A G C T T C C A T C G T T C C T T G C T A C C T A C G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C G A A G C T T G C T A C G T T G G T A G G T T C C T T C C A A G C T A C C T A G C T T G C T A G G A A C C T A G C T A C C A A C C T A G C A +146 A G C T T G G A T G C T A G C T A C G A A G C T A G G T T G G T A C C A A G G A T C C T T G C T T G G A A C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G T T C C T T G C T A C C A T G C T A C C A A C G A A G C T T C G A T C G A T G C A A C C T A C G A T G G T A G C T T G C A T C C T A G C A T G C A T G G T T C C T T C G A A G C T A C G A A G C T T G G T A G C A T G G A T G C A A G G A T G C A A G C T A C G A A C G T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T G G A T G G T A G G T A G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C C T A C G T A C C A A G C A A G G T A C G T A C G A T G C T A G 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G T A G C A A C C A T G C T A G G A A G G A A C G T A C G A T G C T T C G A A G C T T C G T A G G T T C G A A C G A A C C A A G G A T G C T T C C T T C C T T C C T A G G T T G G T A G G A A C C A A G G T T C C T A G C T A C G A A C G T A G G A T C G T T C G A A C C T T C G T A C C T A C G A A G G T T G C T T G C T A C G T A C C A T G G T A G C T A G G T A C G T T C G A T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C A A G G T T G C T T C C A T C G A T G G A A G G A A G C T A G C A A C C T T G G T A G C A A C C A A C G T T C C T T G G T T G G T A G C A A G C A A G G T T C G A T C G T A C C T T C C T T G C A A C G T A G G T A G C T A G G T T G C A A G C T T G C T T C C T T G C T T C G T T G G A A C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C C T T G C A A C C A A C C A A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C A T G C T T G G A A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G C T A C C T A G C A T G G T A C C T T C C T A G C T A G C A A C G T A C C T +147 T C C T T G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C A A G G T T G C T T G C T T G G A A G G A A G C A A C C T A G C T A C C T T G C T T G C T T G G T T C C T T C C T T G G T T G G T T G G T A G C A T C G T A C C A A C G A A G C A T G C A A C G T T G C A A C C T T C G T T G G T T G C T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G C T A C G A A G C T T C G T A G G T A G C A A G G A T G G A A G G A A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C T A G G T A C G T A G C T T C G T A G G T T G C A A C G T A G G A A C G T A C G A T G C T A C C T A C G T A C G A A G G A T C C A T C G T T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T G G T A G C T T G C A A C G T A G G A A C G A A C C A A G G T T C C A T G G A A G G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T T C G A T G C A T C C T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T T C G T A G C T T G C T A G C A A G G T A C C T T G G A T G C A T C C T T C C T T G C A A G C A T G G A A C G A T G G A A G C T A G C A T C C A A G C A A C C T A C C T T C C T T C C A T C G T A C C T T C C A T G G A A G C A T G G A A G G T T C C A A G C T A C G A T C C A A C C T T G G A A G G T A C C A T C C A A C C T A C C A A G C T A C C A A G G A A G C A T C C T T G G A T C G A A G C T A G G T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C T T C G A T C C T A C G A A C G T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T T C C T A C C A A G C T A C C T A C C A T G G T T G C T A G G A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T A G C T A C C A T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T T C G A A C C T A G C A T G C A A G G A A C C T A G C A A C C T T C C A A C C A T G C A A G G T T G C A T C G A A G G A A G C T T G C T T C G A T C G T A C G T T C G T T C C A A G C A T C C T A C C T A G G T T C G T T G G T A G C T A C C T A G G T T C G T T C G T A C C T A G C T T C G T A G C A T G C A A G G A A C G A A C C A T C G A A G C A A C C T A C C T A C G A A C C A T C C A T G C A T G C T A C C T A C G A A G G A T C G A A C C A T G C T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C T A G C T A G C A A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +148 A C C T A G G T A C G T T G C T A G C T T G C T A G C T A G G A T C C A A C G T T C C T T G C T A C G A A G G A A G C A A C C T A C C T A C C T T C C T T G C A T G G T A G C A T G C A T G G T T G G T T G G T A G C A T C G T A C C T A G C T A C C A T C C T T C G A T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A A G G A T G C A T C C A T G G A T G C T T C C A T C G T T C G T A G G T A G C A A C C A T G G A A G G A A C C A A G G A A G G A T G C A A G C A A C G T A G G T T C C T A G G T T G G T T G G T A C C T T G C T A G C A A C C A A G G T T G C A A C G A A C G T T G G A T G C A A C G T T G G T A C C T T G G T T C C T A G G A A C G A A G C T T C G T A G G T A G C A A G C A T G G T A G G T A C C A T G C T T C C T A G G A A G C T A C G T A G C A A C C T T G C T A C G A A G C T T G C A T G G T T G G T T C G T T C G A T G G A A G G A T G C A T C G T T G G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T C C A T G C A A C G T T C C A T G C T T G G T A C C A A C G A T G G T A C G A T G G A A G C T T G G A A G C T A G C A A C C T T G G T A C C A T C G T T C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C C T T C G T A C C A A G G A T G C A A G G A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T G C T A C C T A G G A A G C T A C G T A C C T T G G A T C G T T G G T A G G T T C C T T G C A T G C A T G C A T C G T A G G T T C C T T C C A A G G T A G G T T G C A A G C A T C G A T G G A T G C A T C C A A C C A A G C T A G C A A G G T T C G A A G C T T C G A T C G A T C G A T G C T T G C T A G G T A C C A A C C T A C G A T C C T A C C T T G C A A G G T A G C A T G C T T C C A T G C A A C C T A G C A T C G A A G C A T C C A T G C A A C G A T C G A T C C T A G C A A G C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T G G A T C G A T C C A A C C A A G G A A C C T T G C T A G G A T G G T T G C T A G G T A G C T A G G T A C G A T C G T A C G T A C C A T G C T A C C T T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A G G A T C C T T C C A A G C T T C C T A G C A T G G T T C G T T C C A A G C T A C G T T G G T T C G A A C C T A G G T A C C A T G C T A G C T A G C A A C C A A G C T T C C A T C G T T G G T A G C T A C G A T G G A T G C A T C C A A G C A T G G A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C G T A G G T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +149 A C C T A C G T A C G T T G C T A C C T T G C T A G G A A C G A A C C A A G G A T C C T T G C A T G G A A C G A A C C T T G G T A G C T A C C A T G C T A G C T T G G T T C C A T C G A T C G A A G G T T G G T A G C A T C C T A C G T A G G T A G C A T G G A T C G A T G C T A G C T T C C A A G C T T G G T T C G A T C C T A G C A A G G A T C C T T C C A T G G A A G C T A C G A A G C T T G G T A G C T T G C A A G C A A G G T T G C T A G C T A C G A T C G T A C C T A G C T A G C T A C G T T G G T A G C T A G G A T G C T A C G T A G C T T G G A A G G A A G C T T C C A A C C A A G G A A G G A T G G T T C C A T G C A A C C A T G C A A C C T A G G T T G G T T G C A T C G A A C C T A G G A A G C A T G C T A C G T T G G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T T C C A A G C A T G C A T G G T A C G A A G C T A G G T T C G A T G C T A G G A T C G T T G C T A C G A A G G T A G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G G T T G G T T G C A A C C T A G C A T C G A A G C T A G C A T C C A A C C A A G C T A G C A T C C T T C G T T C G T T C C T A C G T A G G A A G C T T G C T A G G T A C C A A C C T A C G A T C C T A C C A A C C A A G G T A G C A T G C T T C C A T G C A A C C T A G C A A G G A A G C A T C C A T G G A T C G A A G C T T C C T A C G T A G C A T C C T A C G A A C G A A G C T A C G T T G C T T C G A A C C T T C G A A C G T T G C T A G G A T C C T A G G A T C C T A C C T A G C A T C G T A G G A A C G T A G G A T G C A A G C T T C G T A C G A T G G T A G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C C T T G G T T G C T T C G A A C G T T G G A T G C A T G C A T G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G C T A C C T A C C T A C C T A G C T A C C A A C G T T G G T T G C A A G G T A G G A A C C A T G G A T G C T A G G A T G G A T C C T T C C A A C G T T G G T A C C T A G G T T G G A T G C T T G C T A C G T T G C T T C G A A C C T A G G T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C G T A G C T A G C T A C C T A C C A T C C A T C C A T C C A T G C T T C C A A G C A T G C T A G C T A C G T A G G T A C C A A C G A T G C T T G G A A G C T T C C T A G C A A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G G A A C G T A G C T A C C A A G C A A C C T A G C T A G G T A G C A A C G T +150 A C C T A G G T A C G T T G C T A G C A T G C T A G C A A G C T A C G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A C C T T G G T A G C A T G C T T G G T T C G T T G C T T C C A T C C A A C C A A C G T A G C A T G C A A C C T T C C T T C C T T C C A A G G T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G A A G C T A G G A T C G T T C C A A G C A A G C T A G C A A G G A T G C A A G C T A G C A A C C T T C C A A G C A A C G T A G G T T G G T A G G T T G G T A G G T A G G A A G C A T G G A A C G A A G G T T G C A A C G A T G C T A G G A A G G T T G C T T G C A A C C A T G C A A C C A T C G T A G G T A C G A A C C T A C G A T G C A A G C A A G G T A C G T A C G A T C C A T C G T A C C T T G G T T C G A A G G T T C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G C A T C G A T G G T A G C T A G G T T G G A A G C T A C C A T G G T A C C A T G C A A C G T T C C A T G C T T G G T A C C T T G G A A G G T A C C T T G G T T G C T A G C T A C G T A C C A T G G A T C C A A G G A A G C T T C G A T G G T T C C T T G C T T C G T T G C T A C C A A C C T A G C T T G G T T C G T A G G T A C G A A G C T T C G A A C C A A C G A A G G A A C C A A G C T A C C T A G G A T G C T T G C T A G G A A G G T A G C A A C G T A G G A T G G A T C C T T G C T A G G T A C G T A G C T T G G A T G C T T G G A T G C T T C C T A C G T T C G A A C C A T G G T A C C A T G C A A G G A T C G A T C C A A G C A A C C T A C C T A G G T T C G A A G C A T C G A T C C A T C C A T C C A T G G A T G C T T C C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A C C A A C C A T C C A A G C T A C C A T G G A A G C A T C G T T C C A A C G A T C G A T C C T T G G T A G C A A G C T A C G A A G G A A G G T A C G T T G G T T C G A T C C T A C G A A C G A A C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G A A C G T A G G T A C C T A G G T A C C T A C G A T G G A T G G T A G G A T G C T T C G A A C C T T C G T T G C T A G C T A G G A T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C A A G G T T G G T T C G A A C C T A G G A A G C T T G C T A G C A A G C A A C C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G C A A G C A T G G T A G G A T G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G G T T C C T T G G T T C G T T C C T T G G T T G C A T C G T A G C T A C G A A G G T T C G T T C C T T C G T T G C T T C C T A C C T A G C A T C G A T C G A A G C A T G G T T C C T A G G A A G G T T C G A A C G A T G C T T G C T A G C A A G C A T G G T A G G A T C G A T C C A A C C A T C G T T G C T T C C T T G C A A G C T T G C T T C C T A G C T A C C T A G G T A C G A T G C A T G C T A G C A T G C A A C C A A C G T +151 T G G T T G G A T G C T T G C T A C C T T G C T A G G T A G C T A C C T A G G T T G C T T G C T T G G T T C G A T G C A T G G T A G C A T G C T T C C T T G C T T G G T T C C T T G C A T G G T T C G T T G C T T C C T T C C A A G C T A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A A C C T T C C A A C G A A G C T A G C A T C G T T G G T A G C T A G C T A G C A A G G A T G C A A G C T A G G A A C G A T C C T A G C T A G C T A G G T T G C T A G C T T C C A A C C T A C C T A G C T A C G A T G G T A G C T A C C A A C G A A G G T A G G T T G C T A G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C G A A C C A T C C A A G C A T G G A A G G T A C G A T G C T A G C T A C C T T C G A A C G A A C C T T C G T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A A C C A A C G T T G C A T G C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C A A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A T C C A A G C A A C C A A G G T T C G T A G C A T C G T T C C A A C G A A G G T A G C T T G G T A G G A T C G A T G C T A C G T A G C T A C C T A G G A A G C T A C C T T G C T T C C A T C C T A C G T T C G A A G C A T G G A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T T C G A T C C A A G G T T G G T A G G T A G C A A G G T T G C T T G C T A G C T A G C A T C G T A G G A A C C A T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C C T A G C T T G C A T C C A T G G A A C G T A G G A T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T A C C T A C G T A G C T T G C T A C G T A G G A T G C A A G G T T G C T A G G T A C G T T G G A T G C T A G C A T G C A A G C T T G C A A G C A A C C A A C C T A G G T A G C T A C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G G T T G G T A G G A A C G A T G C A A G G T A G C A T G G T A G G A T G C A A G G T T G G A A G G A T G G A T C C T T C C A A C G T T G C T A C C A A G C T T G G A T G C A A G C T T C C T A G C T A G G T T C C T T G G T T G C T T C G T A G C T A C G A A G G A A G C T T C C A T G G T T G C T A C C T T C C A T C G A T C C A T C G A A G C T T G G T T G C A A G G A A G G A T C G A A C G A T G C T T G C T A C G A T G C T T G G A A G C T T C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G C T A C G T A G G T A C G A T G C A T C C T A G C A T G C A A C C A A C G T +152 A C C T A G G T T C C T A G C T A C C T T G C T A G G T A G G T A C G A A G G T T G C T T G C T T G G A A C G A A C C T A G G T A C C A T G C T T G G T A G C T T G C T A G C A A C G A T G G T A G G T T G G T T C C T T G C T A C C A A C G A A G C A T G C A A C G T T G C A A C C T T C C A A G G T T G C T T C C A T C C T A G C A T C C A T C G T T C C T T G C A A G G A A C G A A G C T T C G T A C C A A G C A T G G A A G G T A G C T A C C T A G C A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A C G A A C C T T G C A A C C T T C C A T C C T A G G A A C G T A G C A A C C T A C G A T G C A A G C T A G G A A C G T A C C T T C C T T C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C C T T C G T A C C A A G C A T G G A T C G A T C C A A C G A A G C A A G C T A G C T T G C A T C G T T G G A A G G A A G G T A G C T T G G A T G G A T C G A T C G T A G G A A G G T A C C T T G G A A G C A T G C T T G G T A C C A T C C A T C G A T G C A A G G A A G G A T C C T A C G A T C G A T C G A T G C T T C C T T G C T A G C A A C C T T C G A A G C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T A G C T A G C A A C C A A C C T T G G A A G G T A C C T T C C A A G C A T G C A A C G A T G C T T C G T A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C T T C G T A G C A A G G A T G C T T G C T T C C T T C C T A G G T A C G T A G G T A G C A A G G T T C G T A C G A T G G T T C G T A G G T A G C A A C G A T C G A T C G T A C C T A G G A A G G T A G G T A C G T A G G A T G C A T G G T A G C T T G G T A C G T T C G T T G C T A G G A A G C T A C C A T G C A T C C T A C G T A C C T T G C T T G C A A G G A T G C T T C C A T C C T T C G T A G G A A G C T A G C A A G C T A C C T T G G A T C G T T G C A A G G T T G G T T C G A A G G A T G C T A G G T A C C A T C G A A G C T T C C T T C C T A G G T T C G A T G C A T G C T A G G A T G C T T C G T T C C T T G C T A G C T T C C T A G G T T G C A T G C A A G C A T G C A A G G A A C G A A C C T T C G T A G C T A C C T A C C A A C G T A C C A T C C A T G C T T G G A T G G T A G C A T G C T A G C T A C G T A G C T T G C T A C C T T G C T A G C A A C C A T C C T T C G T A C C A A C C T T C C A T C G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G A A C C T T G C T A G C T A G C A A C G T A C C T +153 A G C T T G G T A C G T T G C T A G C T A G C T A G G T A G C T A C G A A G G A T G C T T G C T T G G A T G G A T G C A A G G T A G C A T G C T T G C T T G C T T G G T A G C T T C C A T G G A A C C T T G C T A C C T T G C T A C C A A C G A A G C T T G G A A C G T T G C A A C C T T C G A T G C T T G G T T G C A T C C A A G C T T C C A T G C A T C C A T G G T A G C T A G C A T C G T T C G T A G C T T G C A A G C T A G G A T G C A A C C T A G G A T G C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A C G A T G C T T G G A T G G T A G C T A C C A A C G A A G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A G G A T C C T A G C T T C G T A G C T A C C A A G C T A G G A A C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G T A G G T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T C C A A C C A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C A T C G A T C C T T G G A A G C A T G G T A G G T A C C A A C G T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A G G A A C G A A G C T A C C T T G C T T G C A T C C T A C G T A G G T T G C A A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C C T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A G G A T G C T A C G A T G G T T G C A T G G T T G C T A G G T A C G T T G G A T G C T A C C A T G C T A C C T T G C A T G G T A C G T A C C T T G C T T G C A A G G T A C G T A C C A T C C T T C G A A G C A A G C T T C C A A G C T A C C T T G G A A C G A T G C A A G C A T G G A T G G T A G G A T G C T T G G A A C C A A G G T A C G T T G C T T C C A A G C A T C C T A G C T A G C A T G G A T G C T T G C T A C C T A G C T A G G T T C G T T C C T A G C T A G G T A G C T A G C A T C C A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +154 A C C T A G G T A C G T T G C T A G C A T G C T A G G A A G C T A C C T A G G T T G C T T C C T T G G T T G G A A G C T T G G T A G C A T C C A A G C T A C C T A G G T A G C A T C C A T G G A A G G T T G C T T C C T T C G T A C C A A C G T A C G A T G C T T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C T A G G T A C G T A G C T T C G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G T T C C A A G G T A G G T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T C G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T C C A A C G A A G G A A G G T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T C C A T C C A A G C A A C C T A G C T T G G T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A G C T A C G A A C C A T G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C C T A G G A A C G T A G G T A C C T T C C A T G C A T C G T A G G A A C G A T G C A T C C T T C C T A G C T A C G T A G G T T G C T A C C T T G G A T C C A T G G T A G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C T A C C T T C C T A G G A A C C A T C G A T G C A A G G A T G G A A G G A A G C A T G G T T G G T A G G A A C G T T C C T T C C T A C G T T G G A A G C A T G C A T G G A T G C A A G C T T C C T T G C T A C G T T C C T T G G T A G C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C A T C G T A G G A T C G A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +155 T G C T A G G A T C G T A G C T A C C T T G C T A G G T T G C A T C C A A G G T T G C T T G C T T G G A T G G A A G G T T G G T A G C A T C C T A G C T A C C A A G G A T C C A T G C T T G G A A C G A T C G T A G C A A C G T T G C T A G G A A C C A T G G T A C G T T G C A A C C A A C C T A G G T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A A G G A A G C T A G C T T G G T A G C T T G C A A G C A A G G A T G C T A G C T A G C A A G C T T G C T A G C T A G C T A G G T T G G T A G C T T C C T A G G T A G G A T G C T T C C A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T A G C A T C G A T C C T A G C T A G C A T G C T T G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A G C A T C G A A G C A T C G A T C G A A G C A A C C T T G C A A G G A A G G T A G C A A C C T A C G T T C G T T G G A T G G T A G G T A G C T T G G T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T T G C A T G C A A G C T A C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A C G A A C C A T G C T T C G A A C C T A G G A A G G T T G C A T C G A A C C T A G G A T C G T T G C T T G C A T C C T A G G A A C G T A G G T A C C T A G G T A C C T A C G A T G G A T C G T A G C A T G C T T C G A A C C T T C G T A C C T T C G T A G G T T G C T T G G A T G G T A C C T A G G T A G C T A C G A A C G T T G G A T G C A T G C A T G G A A C C T T G G A T C G A A C G A A C C T T G C T A G C A T G G A T G G T T C G A A C C T A G C A A C C A A G C T A G C T A G C A A C C T A G C A T C C A A C G T T G G T T G C A T G G T A G G A A G C A T G G A T G C A A G G A A G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G G T T C C T T G C T T C G T T C C T T G G T A C G A T G G T A G C T A C C A A G G A A G C T T C C A T C G T T G C T A G C T A C C T A G C A T C G A T C G A A G C A T G G T T G C A A G G A A G G T T C G A A C G A T G C T T C C A A C G A T G C T T G G A A G G A T G C A T C C T T C G T A G G T T G C T A C G T T G C A A G C T T G C T T G C T T G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +156 A G G A A C G T A C C T T C C T A C C T T G G A A G G T A C G T A C C A A G G T T G C T T G C T T G G A A G G A A C C A A C C T A C C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T G G T T C C T T G C T A C C A A G C A A C C A T G C T A C G T T C G T T C C T T C G A A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C C A T G G A T G C T A G C T A G G T T G G T A G C T T G C T A C G A A G G T T G C T A G C T A G C A A G C A T G C T A G G T A G G T A G G T T G G T A G G T A G G T A C G T A C C T T G C T A G C A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A C C T A C C T T C G A A G G A A G C A A G G T T G G T A C G A A G C T A G C A T G G T A G C A T G G A A C C A T G G A A G C A A C C A A G G A T G G A A C C T A C C T A G G A A G C A T G G T A C G A T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C T T C C A A G G T A C G T A G G T A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C G A A G C T A G G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G G A A C C T A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G G A A G G A A C C T A G C A T G C T T C C T T C C A T G G T T G G A A G C A A G C A T C G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T C C T A G G A A C G A T C G A A G C T T G C A A G G T A G C T T G C T A C G T A C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C A A C G A A G C T T G G T A C C T T G C T T G C A T C C T A C G T A G G T T G C A A G G A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C G T T G G T T G C A A G G T A C C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C C T T G G T T G C T A G G A A C G T T C G T A G C A T C C A A C C T T C C T T G C A T C C T A C C T A C C T A G G T A G C T A C G T A C G T A C C A T C C A T C G A A G C T T G C T A G C T A G C T T G G T A G G A A C C A T G C A A G G T T G G T T G G T A C G A T G C A A G C A T G G T T C G A T G G T T C C T T C C T A C G T T C G A A G C A A G G T T C G T T G C A A G C T A C C T A G C T T C G T T C G T A C C T T G C A T C G A A G C A T C C A A G G A A C G A A C C A T C G T A G C T A C C T A C C T A G C A T C C A T C C A T G C A T G C T T C C T A G C A T G C T A G C T A C G A A G G T T G C T A C G A T G C T T G G A A G C T T C C T A G C A A C C A A C C T T G C T T C G T T G C A A G G T T G C T T C C T A G C T A C G T A G G T A C G A T G C A T C C T A G C A T G C A A C C A A C G T +157 A G G T A C G T A C G T A G C T A C C T A G C T A G G T A G C A A C C T A G C A T G C T T G C T T G G T T C G A T G C T T G G T A G C A T C C T T C C T T G C A T G G A T C C A A G C T T G G A A C G T T G G T A G G T T C G T A G C T A G G T A G G A T G C T T C C T T C G T T C C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G C A A G C T A C G A A G C T T C G T T G C T T G C A A G C A A C G T T G C A A G C T A G C A A C C T T G C A A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T A C G T A C G T A G G T A C C A A C G A T G C T A C G A A G C T T G G T T G C A A G C A T G C T A C G A A C G T A G G T T G C T A C G A A G C T A G C A A C C T A G G A T C G A A C G A T C C A A C G T A C C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C C A A G G T A C G A T G G T A G G T A G G A A G G A A C C A A G G T A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T T C C T A G G T A C C T T C C T T C C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C G A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G A A C C A A G C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G T T C C T A G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T A G G T A C G A A C C A T G C T T C G A A G C T A G G T A C G T T G C T T C G A T C C T A G G A A G G T A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A C C A A G C T A G C A T G G A T C G T A G G A T G C T T C G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T A G C T T G G T A C G T T G G A T G C T T G C T A G C T A C C A T G C A T G G T A C C A A C C T T G C T T G C A A G G A T C G T A C C A T C C T T G G A A C G A A G C T T C C A A G C T T G C T T G C A A C C A T G C A A G G T A G C T T G G T A C G A T G C A A G C A T G G A T C G A A G G A T C C T T C C T A G C A T G C T A C C T A G C A T C G T T G C A T G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G A A G C T A G G A A G G A A G C T T C C A T C G T T G C A A C C A A C G T A C G T T C C A T C C A T G C A T C G A T C G T A G C A T G G A T C G T A C G A A G G T A C C T A G C A A G C A T G G T A G G A T C G A T C C A A C C A T C C T T G C T T G G T T G C A A G C T T G C T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +158 A C C T A C G T A C C T T G C T A C C T T C C A A G G A A G C T A C G A A G G T A G G A A G C A A C G A T G G A T C C T A C C T A G G A A C C T A G C A A C C T T G G A T C C A T C C T T C G A A G C T T G G T A C G A T C C A T C G A A G C T A G C A T C C T T C G T T G C T A G C T T C C T T G C T T G C T T C C A T C C T A G C A A G G A T G G T T C C T T G G T A G C T A C G A A G C T T C G T A C C A A G C A T G G A A G G T A G C T A C G T T C G A A G C T A C C A A G C A A C G T A G G A T C C T A G G T A G G T T G G T A C G T A G C T T G G A A C G A A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C A T C C A T G C T A C C A A C G T T G G T A C C T A C C T A C C T A C C A A C G T A G G T A G G T A C G A T G C T A C C T A C C T T C C A A G G A T C C A A C C A T G G T T C G T T C C A T C G T T C G T T G C T A C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G A A G C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T T G C T A G G A A G C T A C C T T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A A C G T A G C A A G C T T G C A T G G T T C C T A G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A T C G A T C C T A C G T A C G A A C G T A C G A A C C A A G G A T G C T T C C T T G C A T C C A T G G T A C G T A G G T A G C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A G G A T C C A A C C A A G G A A C C T T G C T A C G T T G G T T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C T T G G A A C C T T C G A T C C T A C C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G T A G C A A G G A A C C A A G C T T G G T A G C A A C C A T C G T T C C T T G G T T G G T A C G A T G C A A C C T T G G T A G G A A G C T T C C T T C C T A G G T A C C T A C C T A G G T T G G T T G C A A G C T A C C T A G C T T C G T T C C T T G G T T G C A T C G A A G C T A G G A A G G A A C C T A C G A T C G T T G G T A G C T A C G A A G G A T C C A T C G A T C C T A G G A T G G T A C C A T G G T A G C T A C G A A G C T T C C A A C G A A G C T T C G A A G C T T C C T T C C A A C C A T C G T T G C T T C C T T C C A A G G T T G C T T C C T A G C A A C C T A G G T A C C A A C C A A C C T A G G T A G G T A G C A A C G T +159 A G C T T G G A T G C T T C C T A C C T T G C T A G G T A C G T A C C A A G G A T G C T T G C A A C G T T C G A A C C T A G G T A C C T A C C T T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T C G T A C C T A G G T T G C A T G C A A C G T T G C A A C C T T C G T T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G G A A C G A T C G A T C G T A G G T A G C A A G C A T C G A A G G A T C C A A C G A T G G A T C C T T G C T T G C T A G G T T G C T A C C T A G G T T G G T T C G T A G C T T G C A A C G A A G G T T C C A A C G T T G G T T G G A T G C A T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C G T A C C A T G C A A G C A A G G T A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A T C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C G T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A G G T T G C A T G C A T C G T T G G T T G C A A G G A T G G A T C C A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G T A C G T A G C A A G C A T G G A A G G T A C C A A C C T A C G A A C G T A C C A A G C T A G G T A C C A A G C T T G C A T G C A A G C T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A G G A T C G T A C G A T G C T T C G A A G C T A C G A A C G T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T T G G A T G C A A G C T T C C T A C G A T G G T T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T G C T A G C A T C C A T C G A T G C A A G G T A G C T A C C T A C C T T G G T A C C A A C G T T G G T T G G A T G G T A C G A A G C A T G G A T C G A A G C A A C C A T C C T T C C T A C G T T G G A T G C T A G C T T G G A T G G A A G C T A C C T A G C T A G G T T C G T T C C T T G C T T C G A A G C T A G G A A G G A A C C T A C C T T C G T A G C T A C C T A C C T A G C A T C G A T C G A T G C A A G G A T G C A A G G A T C G A T C G A A C G A A G G T T C C A A C C T T G C T T G G A A G C T A C C T T C C T T C G A A G G T T C C T A C C T T G C A A G C T T G G T T G G T A G C T A C C T A G G T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +160 A C C T A C G T A C C T T C C T A C C T T G C T A G C T A C C T A C C A A G G T T C C T T G C A T G G A A C G A A G C T A G G T A G C A A C C T T C C T T G C A T G C T A G C A T C G A T G G T T G G T T G C A A G C A T C G T A C C A A G G A A G C T T G G A A C G A T G C T A G C A A C G A A G G T T G C T T C C A T C C T A G C A A G G A T C C T T G C A T C G T T C C T A G C A T C G A T C G T A G C A A G G A T C C A A G G T T G C T A C C T A C C A A G C T A C C T T G C T T G C T A C G T T G G T A G G T T G G T A G G T A C C A T G C T A C G A A C G A A G C T T C C A A C G A A G C T A G G A T G C T T C C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T G C A A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T C C A A C C T T G G T A C C T T G G A A G C T A G C T A C C A A C C T A G G A A C G T A G C A A G G A T C C A T G G A A G C T A C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G C A A C C A A C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T A C C A T C C T A C G T T G G T A G G A T G G A A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A T C G A A C G A A C G A T C C A T G C A T G G A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A C C T A C C A A G C T A C C T A C C A T G C A T G G T A G G A T G C T A G G A A C C T T C G T T G C T A C G T A G G T T G C T T G G T A C G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C A A C C T T G C T T G C A A G G T A C G T A C C A T C C T T C G A A G C A A G C T A G C T A G C T A C C T T G C A A C C A T G C A A G G T T G C A A G G T A G G A A C C A A C C T T C G T A G G A A C G T A C C T T C C A A G C A T C C T A C C T A G C T T C G A T C C A T G C T A C C T T G C T A G G T T C C T A G G T A C G A T G G T A G C T A G G A A G C T A G C T A C C A T C G A A G C T T C C T A C G T A C G A T C C A T C G A T G G A T C G T T G C T A G C A T G G A T G C T A C G A A G G T T G C A A C G A T G C T T G G A A G C T A C C T A G C T A C C T A G G T A G C A A C G T T G C A A G C T T G G T T G C T T G C A T C C T A G C T A C C T A G G T A C C T A G G T A G G A A C C T A G C A +161 A C C T A G G T T C G T T G C A A C C T A G C T A G G T A G C T A G G A A G G T T G G T T C C T T G G T T C G A T C C A A C C T A G C A T C C A A G C T T G C T T G G T A G C A T G C A T G G T A G C T A G G A A G G T T C G T A C C T A C G T A G C A T C G A T C C T T G C A A C C T T C G T A G G T T G G T T C C A T C C T A G C A T G G A T C C A T C G A A G G A A G G A A C G T A G G T T G G T A G C T A C G A T C C A A C G T T G C A A C C T A C C A A C G T T G C A A G C T A G G T A G G T T G G T A G C T A G G A A G G T A G G T A G C T T C C A T G G T A G C T A C C A A C C A T G G T A G G T T G C T A G C T T G C A T C C A T G C A A C C A A G G A A C G A T G C T A C G A A G C T A G G A A C C T A G G A A C G A A C G T T C C A A C G T A C G T A C G A A G G A T C C A T C G A T G G T T C C T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T C G T A C C T T G C A A C C A A G G A A G C T A G C A A C C T T G G T A G C A A G G T A C G A T G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C C T T G G T A C C A A G C T A G G A T G G A T C C T A G C A A G C A A G G T A C C T A G C A T G C A T C C T A C C T A G G A A G G A A C G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A C C T T G C A T G C A T C C T T C C A T G G T T G G A A G C A A G C A T C G A T C G A T G C A T G C A A C C T A C G T T G C T T G C T T C C A T C C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T T G G A A C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G C A T C C A A C G T T G C A T G C T A C G T T C G A A G G T A G G A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T A G C T A C G T A G G A T G C T A G C T A C G T A C C A T G G T T G C T A G G T A C G T T G G A T G C T A G C A T G C A A C C T T G C A T G G T T G C T T G C T A C G T T G C A A C C T A C G T A C C A T C G T T G G A A G G A A G G A A C C A T G G T T C C T T G C A A C C A T G C A A G C A T G C A A G G A A G G A A C G A T G G T T G G A A C G A A C G T T G C T T G C A A C G T T G C T A C C T A G C A T G G A T G G A T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G A A G C A T G C A A G G A A C C T A C C T T C G T T G C A A C G T A C C T A C G A T C C A T C C A T G C A T C G T T G C A A G C A T G C T A G C T A C G T A G C T T G C T A G C T T C C A T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C T A G G T T G G T T G C T T G C T A C G T A G C A A C C A A C G T T C C T A G C A T G G A A C C T A G C T +162 A C C A A C G T A C C T T C C T A C C T T C G A A G G T A C G T A G G A A G G T T G C T T G C T T G G A A C G A T C C T T G G T A G C A T G C A T G C T A C C T T G C T A G C T T G C T T G G A T C C T T G C T A C C A T C G T A C G T A C G A T G G A T G C A T C C A T G C A A C C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A T C C A T C G A A G G A A G C T A C C A T C G A T C G T A G C A A C C A A G C A A G G T A G C A A G C T A G C A A G C T T G C T A G C T A G C T A C C T T G G T A C C A T G G T T G C T A C G T A G C T T G G A A C C A A G C T T C C T A C C A T G G T A G G A T G G T T G G T T G C A T C C A T G C A A C G A A C G T T G G T A C G A A C C A A G G T A C C A A C G T A G G A A G G T A C G A T G C A A C C T A G C T T C G T T C G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T A G C T T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A T G C T A C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C T A C C A A C G T A G G T A C C A A G C T T G C A T G G T A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G G A A C C A A G G T A G C A T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G G A A G C A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C A A G C A T G C T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G C T A G C A A C C T A C G T A C C A A G G T A C C T T C C T A C C A T G C T A G C T A G C A T C G A A G C A T C C A T G G T A C G A T G C T A G G T A G C A A C C A T G C T A C G A A G C T A G G T A G G A T G C A T C G A T C C T T C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C A A G C A T C C A T G G T A C G T A G G T A G C A A C C A A G C T T G G A T C G A T C G T T C G T T G C A A G G A A C C T T C G T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T G G T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C C T T C C T A C G T T G C A T G G T T C G T T C G A T C G T T C G T A G C T T G C T T C C A A G C T A C C T T G C A A C C A T G C T T G G T T G G T T G G T A G G A A G C A A C C T T C G T A G C A A C C A T C C T T C C T A C G T T C G A T G C T A G G T T C G T T G G A A G C T A C C T A G C T A G G T T C G T A G G A A G G T A G C A A G C T A G C A A G G A A G C T A C C A T G C T A G C T A C C T A C C T A C C A T C G A A G G A T C C T A G G T T G C A T C G A A G G A T C G T A C C T T G C T T G C T A C G A T G C T A G G A A G G A A C C T A G C A A C C A T C G T T G C T T G G T T G C A A G C T T G C T T C C A A G G A T C G A T G C T A G C A A G C A T C G A A G C T A C C A A G G T A C C T +163 T G C A A C G T A C C T A G G A T G G T A C G A A G G T A C G T A C G A A G G T T C C T T C C T T G G A A C G A T C C T A G G T A G C A T G C T T G C T A G C A T G G T A C C A T C G A T G G A A C G T T G G T A C C A T G G T A C G T A G G A A G C T T G C A T C G T T G C A A G C T T C G A A G G T T G C T A C C A T C C A A G C A A G G A A C C T T C G A A G G T A G C T A G C T A G G T T G G T A G G A T G C T A C G A A G G T T G C T A G C T A G C T A G C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C C A T G C T A C C A A C G T T G G T A C C T A C C T A C G T A C C A A G C A T C C T A C G A T C G A A C C T T C C T A G C T T C G T A C G A A G G A A G G T T C G T T C G T T C C T T G C A T G C A A G C T T C G T T C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T A G C T T C C T A G C A T G C A A C G A A G G T A C G T T G G A A G G T A G G A A G C A A G C T A G G T T C C A T G G A T C G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A C C A A C G A T C G A A C C A A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G T T G C T T C G A T C C T A G C T A G C T T G C T A G C A A G G A A G G T T G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G C T A C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A A C G T T G C T A G C T T G C T A G G T A C C T T G C T A C G A A C C T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C G A A C C A T G C T T C G A A G C A A G G T A C C T T G C T T G C A T C C A A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T T C G T A G G T T G C T T G G T T G G T A C C A T G G T T G C T T G G T A C G T A C G T A C C T A G C A T C C T T C C A T G C A A G C A T C C A A C C T T G C T T G C A T C G A A G C T A G C A T C C T T G C T T G G A A G G A A C G T A G C T T G G T A G C A T C G T T G C A A G G T T G G A T G C T T G C A A G C A A C G T T G C A T G C A A C C A T C C T T C C T A C G T T C C A A G C T A G G T T C G T T C C A A G C T A G G A A G C T A G C T T G G T A G G T A C C A T G G A A C C T A G C A A G G A A C C T T C C A T C G A A G C T A C G A A C C T A C C A T G C A T C G A A G C T A G G T A C C A T C G A A G C T A G C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G G T A G C A A G C A A G C T T G C A T C C T T G C A A G C T T G C T T C C T A G C A T C C T A G C T A C C A A G G A A C C T A G C A T G C A A C C A A C G T +164 A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G C A A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C T T G C A T G G T A G C T T C C A T G G A A C C T T G C A A G C A T C C A A C G T A C G T A G G A T G C T T C G A T G C T A G C A A C G A A G C T T G G T T G C A T C C T A G C A T C C A T C C T T C C A T G G A T G G A A C G A A G C T T C G T A G G T A G C A A G C A T G G A A G G A A C G T A G C A A C G T T C C A A G C T A G C T A G G T T C G A A G C T T C C A T G C A A C C T T C C T T G G A A C C T A G G T T G C A A C C A A G G A A G G A T G C T T G C T T G C A T C C T T G G T A C C A T C G T A G G A A G C T T C C T A G G T A G C A A G G T A G G T A C G T A C G A T G C T A G C T A C G T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T T G C A T G G A A C C A T G G A A C C A A G G A T G G A A G C T A G C A T C G T T G G A A C C A A C G A T G C A T C G A T C C A A C C A A C G T T G G A A C C T T G C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A C G A A C C A T G G A T C C T A G C A T C G T A C C A T C G T A C C A T G G A T C G T A G C T A G G T T G G A T C C T T C C T T C G T T G G A T C C T A G C T T G C A T G G T A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G G A A C C T A G G A T C G T A C G T A G C A T C G A T C C A A C C T A G C A A C G T A G C T T C G A T G C T T G G A T G C T T C C A T C C A T G G T T G C A A C G A A C C A T C G A A G C T A C G A T C C A A G C A A C C T T C C T T G C T T C G A T G C A A G G T A G G A T C C A T C C A A G C A T G G T T G C T T G G T A C G A T G C A T C C A A C G A A G G T A G C T T C C A A G C T A G C A A G C A T G C A T C G A A G C A T C C T T G G A T C G A A G G T A C C T A G G T A C C A A G C T A G G A A G C T T G G T A C C T T G C T T C G A T C C T A G C A T G G T T G C A A G G A T C C T T C C T T G C A A C C A A G C A T C C A T G G T A C G T A G G T T G C A A G G T A C C T A C G A T C G T T C G T A G C A T C G T T G G A T C C T T C G T T G C T A C G T A G C T A C C T A C G A A C G T T G C T A G G T A G G A T G G T A C G T A C C T A G C T A G C T T C G A T C C A T G C A T C G A A C G A T C C T A G G T A G C T T C G T T G C T T C C T T C G T T C G T A G G A A G G A A C C A T G C T A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A T G C A T G G A T C G T T C G A A C C A T C G T T C C T A C G T T G G A A G G T A G C T T G G A T G C A T G C A A G G T A C C A A G C T T C C T T G G T T G C T A G G T A G C T A G G A T C C A A G C T T C C A T C G T T C C T A G C T A C C T A C G T T C C A T C G A T G C T T G G A T C G T A G C A T G G T T C C T A C G A A G C T A C C A A C G A T G C A T G G A A G C A A C C T T G C T A C C A T C G T T G C T A C G T T G C A A G G T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +165 A G G T A G G T A C G T T G C T A G C T A C G A T G G T A C G T A C C A A G G A T G C T T G C T A G G A A G G A A G G A A C C A T G C T A C C T T C C T A G G T T G G T T C C A A C C A T C G A A G G A T G C A A G C A T G G T A C C A A G G A T G G A T C C T A C C T T C G T A G C A A C C A T G C T T C C T T C C A T C C A A G C T T C C A T C G A T C G A T G C A A G C T A C G A A G C T T C G T A G C A A G C A A C C A T G G A A G G A A C C A A G C A A C C A T G C A A G C A A C G T A G G T T G G T A G C T T C C A A G G T A C G T T C C A T G G A A C G T A G G A T G C A A C G A A C G T A G G A T G C T A G C T T G C A A C C A T C C A A C G A A C G T A C C T T G C T T G C T A G G T A C C A A C G T A G G A T C G T A C G A T G C A A G C A A C C T T C G A A G G A T C C A T C C T T G C T T C C T T C C T T G C A T G G T A G C T T C G T A G C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T G G A T G C T T G G T A G G A T G G A A G G T A G G T T G G A A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G T A C C A T C C A A G G T T G C T T C G T T G C A A C G A A G G T T G G T T C C T T C G T T G G A T C C A A G C A T G C A A G C A T C C A A C G A A C C A A G G T T C C T A G C A A G G A T C C T A C G A A G G A A G C T T C G T T G G A T C G A T C C T A G C T A G C A A C G T A G C A A G C T A G C T T G G A T C C T T C C T T C C A T G C A A G G T T G G A A G C A T C G A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C G A T C G T T C C T T C G A T C C A T C C A T G G A A G C T T C C T T G G T T G C A T C C T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C G A A C C A T G C T T C G A A G C A A G G T A C C T T G C T T G C A T C C A A C G T A C G A A G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G T A G C T T G G A A C G A A G G T T C C T A C G A A C G A T G G T A G C A T C G T T G G A A C G A T G C A T C C T A C G A A G C T T G C T T G C A A C G T T G C T T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A C G T T G G T T C C T T C G T T C C T A G C A A G C T A G C T A G C T T G G T A G G A A C C A T G C A A G G T T G G T T G G T A G G A A G C A A C C T A C C A A G G T A G G A T C C T T C C T A C G T A G C T A C C T A G C T T G G T T G C A T C G T A G G A A C C A A C G T T C C T T C C T T C C A T G C T A G C T T G C A A G G A T C C T T G C A T C G T A G C A A C C T A C G A A C C T T C C A T C C A T G C A T C C A T C G T A G G A T G G A T C C A A C G A A G C T T G C T A C G A T G C T T G G A A G C A T C C T A G C T A C C A A C C T T G C T T C C T T C C T A G C T T G C T T C C T T G C A T C G T A G C T A C C T A G C T T C G A A G C T A C C A A G G T A C C T +166 A G G A A C G T A C C T A G G T A C G A T G C T T G G T T G C T A C G A A G G T A G G A T G C T A C G A T C G A T G C T T G G T A G C T A C C T T G C A A C C T T G G A T C C A T C C A T C G A A C G A T C C T A C C T T G C T A C G T A C G A T G C A T C C T T C C T T G G A A G C T A C C T A C C T T G C T T G C T T G C A A G C T T C C A T G C A T C C A T C G A A G C T A C G A A G C T T C G T T G G T A G C A A G C A T C G A A G G A T C C T T C G A A C G A A G G A A G C T A G C T A G G A T C C T A G C A A G G A A G G T A C C T A G C A A G C A A C C T A G C A T C C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A T G C T A C C T A C C T A C G A A C G T A G C T A G G T A C G A T G C A A C G T T G G A A G G T T C G A A G G A A C G T T G G A T C G A A G C T T G C A T G G T T C G T T C G T T C C A T G G A A G C A A G C A A G G T T G C A A G C A A G C T A G C A A C G A A G C T A G C A T G C T A C C A T G G T A C G T A G C A T C C T T G C T A G C A A C C A A G G T A C C T A G G A A C C T T C G A A C G T T C C A T C G T A G G A A G G A T G G T A C C A A G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A A G C A A C C A A C G T A G C A A G C T A C C T T G C A T C G T T C C T A G G A A G G A T C C T T G G T A C C A A G G A T C C T A C C T A G C T A C C T A G G T A G C T A G G T T G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G C T A C C A T C G A A G C A A C C T A C C A A G G T T C G A A G C T A C G A A C G T T G C T A G C T T G C T A G G T A C C T T G C T A C G A A C C T A C G A T C G T A G G T A C C T T C C A A G C T A G C A A G C T A C C T T C G T T G C A T G G T A G G T A C G A T G G T T G C T A C G T A G C A A C G T A C G A A G G A T G G T A C G T T G C T T G C A A C C T A G G A T C G T T C C T A C G A A C C T T C C A A C G T A C C A T G C T T C C A T G G T A C G T A G G A A C G A A C C T T C C T A C G A T G C T T C G T A G G A T C G T A C G A T C G A T G G A A C C A A G G A A G G A T G C T A C G A T G G T T G C A T G G T T G C A A G G T A C G A T C C T A G C T A G C T A C G T T C C T T G C A T G G T A C G A A C C T T G G T A G C T T G G T T G G T A C C A T C C A T C G A A C G A A G G A A C C A T G C T A C C T T G G A A C G A T G C A T G C A T G G A T G G T A G G A T G C T A G G T T G G A A C G A A G G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T T C C A A G C A T C C A A G G A A G C A T C G T T G C A A G C A T G G A T C C T A C G A A G C T A G C T T C C A T G C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T A C C A A G C A T G C T A G G T A G G A A G G T A C C T +167 A G G T A C G T A C C T T C C T A C C T T G C T A G G A A C G A A C C A A G G T T G C T T G C T T G G T T G G A A C C T A G G T A G C A T G C T T G C T T G C T T G C T A G C A T C G A T G G A T C C T T G C T A C C A T G C T A C C A A G C A A C C A T C C T T C G T T G C A A G C T T C C A A G G T T G C T T G C A T C C A A G C A T C C A T G G T T C C T T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C A A C G T T G C A A C C T A G C T A C C T T G G A A G C T A C C T A G G T T G G T A G C T T G G A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C C A T G G T A G G T T G C T T G C T T G C A A C C A T G C T A C G A A C G T A G G T A C G T A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G A A G C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A T G C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C G T A G G T A C C T A G G A A G G A A C C A A G G A A G G T A C C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A G G A A G G T A G C A A C G T T G G A T G G A T C C T A G C T A G G T A C C T A G C A A G G A A C C T T G C A T C C A T C C T A C G T T G G A A C G A A G C T A G C A T C G A A G G A A C C A T C C A A G C A A G C T T C C T T G C T T C C A T C G A A C G A A C C A T G G A A G C A T G G A A G G T A C C T T G G T T C G T A G G T A C C T T C C A A G G T A G C A T C C T T G C T A G C A A C C T A G C A T C G A A G C A T C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A C G A A G G A T C G T A C C A T G C T T C G A A C C T A G G A A G G T T G C A T C G A A C C T A G G A T C G T T G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T T C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T G G A T G C A T G C A T G G T A C C A A G C A T G G T A C C A A C C T A G G T A C C T A C C T A C G T A G C A T C C T T C G T A G G A A G C T A G C A A C C T T G G T A G C A T C C A A C G T T C C T T G G T T G G T A G G A A G G A T G C A T G G T A G G A A C C A T C C T T G C T A G G T T G C A T C C T A G C T T C G T T G G A A G C T A C G T A G C T T C G T T C C T T G G T T G C T T C G A A G C T A G G A A G G A T G C T T C C T A C G T T G C T T C G T A C C T A G C A T C C A T C C A T G C T T G G A T G C T A G G A T G G A A C C T A C G T A G C T T G C T A C C T T G C T A G C A A C C A T C C T T C G T A C C A A C C T T C C A T C G T T G C A A G C T T G C T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +168 A C C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T A C C A A G G A T C C T T G C T T G G T T C G A T G C A T G G T A G C A T C G A T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T T C C T T G C T A C C A A C G A A G C T T G G A A C G T T G C A A C C T T C G T A C C T T G C T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G G A T C G A A G C T T C G T A G C T T G C A A G C T A G C T T G C T A C C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T A C C A T G G T A G G T T C G T A G C A T G G A A C G A A G G T T G C A A C G A A G G T A G G T A C G A A C C T T G C A A C C A A G C T A C C A T C G T A C G T A G C T T C G T A G G T T G C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C C T A G G T A C C T T G G A A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A C C T T G G T T G G T T C G A T C C T A G C T A G G T A C C T A G C A A G C T A C C A T G C T A C C A T C C T T C C A T G C A A C C A T G C T T C C A T G C A T G G T T G C A T C C A A C C A A G C T T G C A T G G T A C G T A G C A A C G A A C G T A G G A A G C A T G G A A G G T A C C T T G C T T C G A A C G T A C G T T C C A A G G T A C G T A C C A A C C A T C C T A C C T A G C A A G G A A G C T A C C T T G C A A C C A A G C T A C C T A C G A A C C A T G C T T C G A A G C A A C G A A C C A T G C T T C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A T G G T T G C T A G G T T G C T T G G T A C G T T C G T A G C A T C G A T G C T A C C T T G C A T C C T A C C A A C C T T G C T T G C A A G G A T G C T T C C A T C C A T C G A A G G T A G G A A C C T A G C T A C C T T C C A A C C A T G C A A G G T T G G A T G G T A G G A T C C T A G C T T C G T A G G T A C G T T G C T T G C A A C G T T G G A A G C A A G G T T C G T T G C A A G C A A C G T T G C T A C G A A C C T A G G T A C G A T G C A A G C T T G C A A G G A A C C T T C C T T C G T T G C A A C G T A C C A A G C A T G G A T C G A T G C T T G G A T G C T A C C A T G G T A G C T A G G T A G G A A G C T A C C A T C C T T G G A A G C T T C C T A G C T A C C A A C C T T G C T A C G T T G G A A G G T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +169 A G C T T G G A T G C T T C C T A C C T T G C T A G G T A G C T A G C A A G G T T G C T T G C T T G G A A C G A T C C T A G G T A G C A T G G T T G C A A C C T T G C T A G C A A G C A T G G T A G G T T G G T A C G T A C G T T G C T A G G A A G C T T G G A A C C T T G C A A C C T T C G T A G G T T G C T A C C A T C C T A G C A T G G A T C C A T C G A A G G A A G G A A C G T A G G T T G G T A G C T A C G A T G C A A G G T A G C A A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T A G G T T G G T T C C T A G G A T G G A A C G A A G G T T C C A A C G A A G G T T G G A T G C A A C G T T G G A A G C A T G C T A C G A A C G T T G G A T G C T T C G A A G C T A C C A A C C T A G G A A G G A A C G A T G C A T C C T A G G T T C G T T C G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A T G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C C T T G G T A C C A A G C T A G C A T G G T A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G G A A C C A A G G T A G G A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C T A C C A A G C A T G C T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G C T A G C A A C C A A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A C G A T C G T A G C A T G C A T G G T A C G A T G G T A G G T A C G T A C C A T C C T A C C T T C C T A G C T A G G T T G C T T G C A T C C T A C G A A G G T T G C A A C G A T C C A A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T G G T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C C T T C C T A C G T T G C A T G G T T C G T T C C A T C G T T C G T A G G A A G C T A G C A A G G T T G G T A G C A T C C A A C G T T C C T T G G T T G G T A G G A A C C A T C G T T G G T A G G A A C G T T G C T T G C A A C G T T G G A A C C T A G C A T C C T T G G T T G C T A C G T A G C T A G G T T C G T A G G T A G C T T C G A A G C A T G C A A G G A A C C T A C C T T C G T T G C A A C G T A C C T A C C A T C C A T C C A T G C A T C G A T C G T A G C A T G C T A G C T A C G T A G C T T G C T A C G A T G C T A G G A A G G A A C C T A G C A A C C A T C G T T G C T T G G T T G C A A G G T T G G T T G C T T G C T A C G T A G C A A C C A A C G T T C C T A G C A T G G A A C C T A G C T +170 A C C T A G G T T C G T T G C A A C C T A G C T A G G T A G C T A G G A A G G T T G G T T C C T T G G T T C G A T G C T T G G T A G C A T C C A A G C T T G C T T G G T A G C A T C C A T G G A T C C T T G C A A G G T T C G T A C C T A C G T A C C A T C C A T C C T T G C A A C C T T C C T A G G T T G C T T C C A T C C T A G C A T C C A A C C T T C C T T G G A A G C T A C G A A G C T T C G T T G G T A G G A A C C T A G G T T G C T A G C T A C C A A G C T T G C A A G C T A G C T A C G T T G G T A C C A T G G T T G C T A C G T A G C T T G G A A C C A A G C T T C C A A C C A T G G T A G G T T G C T A G C T T G C A T C C A T G C A A C C A A G G A T C C T A G G A A C C T A G G T A C C A A C C T A G G A T C G A A C G A T G C A A C G T A G G T A C C A A G G A T C C A T C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G C A A C C A A G G A A G C T A G C T A C C T T G G T A G C A A G G T A C G A T G G T A C C T T G C T T C G T T G C A A C G T A G G T T G G A A G C T T C G T A G G T T C C A A G C T T C G T T G C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A G C T A G G T A C G T A G C A A G C T A C C A T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G C A A G C T T C C A T G C A A C C T A C G T T G C T T G G T T C C T T C G A A C G A A C G A T C C A T C C A T G G A T C C A A C C T T G G T A C G A T G G T A C G T A C C T A G C T A C G T T C C T A C G A T G C T A C C T A G C A T G C A A G C T T C C T T G C A A C G A A G C A T C C A A C C A A C C A T G C T A C G A A G C T A G G T A G G A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A C C T T C C T A C C T A C G A T C G T A G G T A G C A A C G A T C G A T G G A T G C T T G G T A C G T T G C T T G G A T G G A T G C A T G G T A G G A T G G T A C G T T G G A T G C T A G C A A C G T T C C T T G C A T C G T A G C A A C C T T G C T A G C T T G G A T G C T T C C A T C C T T G G A A G G A A G G A A C C A T G C T A C C T T G C A A C C A T G C T T G G T T G G A A G G T A G G A T G C T T G G A T G G A A G C A A C G T T G C T T C C T A C C T T C C T A C C T A G C A T C C T T G G A A G C T T C C T A G C T A G G T T C G T T C C T T G C T A G C A A G C A T G C T A G G A A G C T A C C A T G G T A C C A A G C T A C C T A C C A T C G A T C G A T C C T A C G T T G C A A G C A T G G A T C G T A C G A A G C T T C C A A G C A A G C A T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A C C A A C C T T C C T A G G T A G G T A G C A A C G T +171 A C C T T G G A T G C T T G C A A C C T A G C T A G G T A G C T A G G A A G G T T G G T T C C T T G G T T C G A T C C T T G G T A G C A T C C A A G C T T G C T T G G T A G C A T G C A T G G T T C G T T G G T A C C A T C G T A C C A A G G T A C C A T C C A T C C T T G C A A C C T T C G T A G G T T G C T T G C A T C C T A G C A T C C A A C C T T C C T T G G A A G C T A C G A A G C T T C G T T G G T A G G A A C C T A G G T T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T A G G T T G G T T C C T A G G A T G G A A C G A A G G T T C C A A C G A A G G T T G G A T G C A A C G T T G G T A C C A T G C T A C G A A C G T T G C T A G C T T C G A A G G A T G G A A C C T A G G A T C G A A C G A T G C A T C C T A G G T T C C A A G G A T C C A T C C T T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T G C A T G G T A C G T A G C A T G C T A G G T A G G T T G G A A G G T A G G T T G C A A G G T T G C A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G C A A G C A A C G A A G G A A G C A A G G T T C C A A C C A T C G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G G A A G G A A G C T T G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C C A A G C A A G C T A G C T T G G T T C C A T C G A A C G A A C G A T C C A T C C A T G G A T C C A A C C T T G G T A G C A A C C A A C C T T G C T T G C T A C G T T C C T A C G A T G C T A C G T A C G A T C G T A G C A T G C A T G G T A C G A T G G T A G G T A G C A A G C A A C C T A C G A A G G A A G C T A G G T T G C T T G C A A G C T A C G A A G G T T G C A A C G A T C C A A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T T G C A A G G T T C C T A C G A T G G A T C G T A G C A T G C T T C G A A C C T T C G T A C C T T C G T A G G T T G C T T G G A T G G T A C C T A G G T A G C T A G G T A C G T T C G T A G C T A G C A A C G T T C C T T G C A T C G T A G C T A C C T T G C T A G C T T G G A T G C T T C C A T C C T T C G T T G G A A G C T A G C A A G G T T G G T A G C A T C C A A C G T T C C T T G G A T G G T A G G A T G C A A C G T T G G T A G G A A C G T T G C T T C C T A G C T T C C T A G G T T G C T T G C A A G C T T C G T T C C T A C C T T G C T T C C T T G C T A C G T T G C A A G C T A G C A A G G A A G C T A C C A T C G T A C C A A G C T A C C T A C C A T C G A T C G A A G C A T C G A T C G T A G G A A G G A T C G T A C G A T G C T T C C A A G C A A G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C C T T G C T A G G T T G C T T C C T A G C A T C G T A G C T A G C T A G C A A G C A A G C T A G C A A C C T A G C T +172 A C C T A G G T T C G T A G C T A C C T T G C A A G G T A C G A T C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C T T G C T T G C T A G C A T C G A T G G T A G C T T G C A A G G T T C G A A C C T A C G T A G G A T C G A T C C T T G C T A G G T T C G A A G C T T G C T T C C A T C C T A G C A A G G A T G G T T C C T T G G T A G C T A C G A A G C T T C G T A C C A A G C A T G G T A G G T T G C T A C C T A G C A A C G T A C C T A G C T A G G A A G G T T G G T A G G T A G G T A G G T A C G A T G C T T G G A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A G G T A C C A A G C T A C C T T C G A A C G A T C C A A C C A A G C T T C G A A G G T A G C A A C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G T A C C A T G G T T C G A A G G A A C C T A G C T A G C A T C G A A G G T A C C T T G G T A C G T T C G A A G C A A G C A T G G A A G G T T G G A T C G T T C G A T G C A A G C T T C G T T C G T A G C A T G G T T G G A T C C T T G G T T C G T T C G T A C C A T G G T T G C A A G C A A C G A A C G A A C C A A G C T A C C T A G C A T G G T T G C T A G G A A C G T A G C A T C G T A G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A G C T T G C A T G C A T C G T T G C A T G G T A G C A T G G T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T C C T T G C T T C G T T G C A T C G T A C G A A G C A A G C A T G G A A G G T A G C T T G C T A C G A A G C T T C C T A C C T A G G T A C G T T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A C C A T G C T A C C T T C C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A C C T A C C T A C C T A C G A T C G T A G G T A G C A A C G A T C G A T G G A T G C T T G G T A C G T T G C T T G G A T G G A T G C A T G G T A G G A T G G A A C G T T G G A T G C A T G C A A G G A A C C T T G G A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G A A C G A A G G T A C C T A G C T T G C T T G C T A C C A T G C A A G G T T G C A T G G T A C G A T C C A T G G A A C G A A G G T A C G T T C C T T G C A A C G T T G G T A C C T A G C A T C C T T G G T A G C T T C C T A G C T A G G T T C G T T C C T A G C T A G C A A G C A T G C T A G G A T G G A A C C A T C G T A C C T A G C A A C C T A G C A T C C A A C G A T C C T A G G T T G C A A G C A T G G A T C G A A C G A A G G T A C C T A G C A A G C A T G G T A G C A A C C T T G C T T C C T A C G T A G C A A C G T T G C A A G C T T G G T T C C T A G C A A C G T A G C T A C C A A C C T T C C T A G G T A G G T A G C A A C G T +173 A C C A A G G T A C G T T G C T A G C T A G C T A G G T A C G T A C C A A G G T T C C T T G C T T G G T T C G A A G C A A G G T A G C A T G C T T C C T T G C A T G G T A G C T T C G A T G G T T C C T T G C T A C C A A C G T T C G T A G G A A C C A T C C A T C C T T G C A A C C T A C G T A G C T T C G A T C C A T G C T A G C A A G G A T C C A T C C T T G G A T G C T A G C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A C C A T G C T A G C T A G C A A G G T T G G T A G G T T G G A T G G T A C C A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C C T A C G T A C C A A G C A T G G T A G G T A C G A T C C A T C G T A G C T T C G T T C G A A G G A A G G T T C G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G G T A G G A A G C A A G G A A G G T T C C A T G G A T C G T T C G A T G G T A C C T T G G A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G G T T C C A A G C T T C G T T C C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C A T G G A T C C T A G C T A G C T T G C T A G G A A G G A A G G T T G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A A C G A T C C A A G C T T G C A A G G T A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G G A A G G A T G C T A C G A T G G T T G C T T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A G G T A C G T A C C A T C C T T C G A A C G A A G G T A G C T T C C T T G C T A G C A T C G A T G C A T G C A T G G A T G G A A G G A A G G A A C C T T G G A T C G T A G G T T C C T T G C A T G G T T G G A A C C T A G C T T C G T T G G A A G C T T C C T A G C T T C G A A C C T T G G T A G C T T G C A A G C T A G G A A G C A A G C T T C C T T C G T A C C T A G C A A C C T A C C T T C C A T C C A T G C T T G G A T G C A A G G A T G G A A G C T A C G T A G G T A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C G T T G C A A G G T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +174 A C G T A G G T T C C T T C C T A C C T T C G A A G G T T G C A A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C G T A C C T T G G T A G C A A C C A T G G A A C C T T G C A A G C A T C C T A G C T A G G A A G C T T G C A T C G T T G C T A G C T T C C A A G C T T G G T T G C A T C C T A G C A T C C A T C C T T C C A T G G T A G C A A G C A A G G T T G G T A G G A T G C T A C G A A G G T T G C T A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A T C C A T G C T A C C A A C G T T G G T A C C T A C C T A C G A T G C A A G C T A G G T A C G T A C G A T G C T A G C T A C G T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T T G C T T C G T A C C A T G G A T G G A T G G T A G G T T C G A A C C A A C C A A G C T A C C A A C C T A G C A T C G A A G C A A C C A A C G T T C C A T C G A A G G T A G C A T C C A T G G T A C G T T G G A A G G T A G G A A C G T A G C A A G G A T G G A T G G A T C G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A C C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T T G C T T C G A T C C T A G C T A G C T T G C T T G C A A G C T A C C T T G C A T G C A T C G T T G C A T G G T A G C A T G G T A C C A T G G A A G C T A C C A T C C A A G G A A C C T A C C A A G G T T C G A T G C T A C G A A C G T T G C T A G C T T G C T A G G T A C C T T G C T A C G A A C C T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G T A G C T T G G T A C C T T G C T T G C A T C C A A C G T A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G T A G G T A G G A A C G A A C C T T C C T A C G A T G C T T C G T A G C A T C G T A C G A T C G A T G G A A G C A T G G A A G G A T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T T G G T A C C A T C C A T C G A T G C A A G C T A G C T A G C T A C C T T G G A A C C A T G C T T C C T T G G T T G G T A G G A T C C T A G G T T G G T A G G A T G G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C G A A G C A T C C A A C G A A G C A T C G T T G C A A G G A A G G A T C G A A C G A T G G T A C C T A G C A A G C A T G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A T G C A T C C T A G C A T G C A A C C A A C G T +175 A G C T A G G A T G C T T C C T A C C T T C C A A G G A A C C T A C C A A G G A T G C T T G C T T G G A A C G T T G C T A G G T A G C T A C C T T G C A A C C T T G G T T C C T T G C A T G G T T G G T T G G T A G C A T C G T T C C T A G G T A G C A T G G A T C G T T G C A A C C T T C G T T G G T T G C T A G C A T C G T A G C T T C C A T C C T T C C A T G G A A G G A A C G T A G G T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C A A C C T T G C T A G G T A G C T A G G T T G G T T G C T T G G T A G G T A G C A T G C T A C G A A C G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G A T C G A T G C T T C G A A G C T A G G A A C G T A G G A T C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A T C G T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G T A C G A T G C A T C G T T G G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T C C A T G C A A C G T T C C A T G C T T G G T A C C A A C G A T G G T A C G T T G C A A C G T A G G A A C G A A G C A A G G T T C C A T G G A A G G T A C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C C T T G C T A C C A A G G A T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A A G G T A G G A A C C T A G G A A G C A T C G T A G G T T C G A T C C T A G C T A G G T T G C T T G C T T G C A A G C T A C C A T G C A T C C A T C C A T G G T A C C A T G G A A C C T A C G A A G G A T G C A T C G A A G C A A G C T T C C T A G C T T C G A T C G A A C C T A C G T T G G A T G C A T G G A A G G T A C C T T G G T A C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T C C T T G C A A C G A T C G A T C C T A G C A A C C A A C G A A C G T T C G A A G C T A C G T T G C T T C G T A C C T A C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C C A A G G T T C C T A G G A A C C T T C G T A G C A T C G T T G G A T C G A T C C A A C C A A G G A A C C T T G C T A G G T T G G T T G C T A G G T A G C T A G G T A C G A T C G T A C G T A C C A T G C T A C C A T G C A T C G T A C C T T G C T A C G T T G C T A C C T A C G T A C C A T C C A T C G A T C G A A G C T A G C T A C C T T G G T A G C A A C C A T G C A T C C T T G C A T C G A A G G A A G G A A C C T T C G T A G G T T C C A T G C T T C C A A G C A T G C T A G C T A G G T T G G A T G C A A G C T T C C T A G C T T C G A A C C T A G G T T G C A T G C A A G C A T G C A A G G T T C C T A C C T T C G T T G C T A G G T T C C T A C G A T G G A T C G A A G C T T G G T T G C A A G G A T G C T T C C T A C C A A G C T A C C A A C C A T G G T T G G A A G C A A C C T T C C A A C C A T C C T T G C T A C G T T G C A T G C T T G C T T C C T T G C T A C G T A G C A A C C A A C G T T C C T A G C A T G G A A C C T A G C T +176 A C C T A G G A T G C T T C C A A C C T T C G A A G G T A G G T A C C A A G G T T G C T T G C T T G G A A G G A A C C T T G G T A G C A A C C T T C C A A C C T T G G T A G C A A G C A T C G A A G G A T G G T A C C A A G G T A C C A A G G T T G C A T G C A T C G A T G C A A G C T T C C T A C C T T G C T A C C A T C C A A G C T T C C A T G C A T C C A T G G T A G G A T C G A T C G T T C G T A G G T A G C A T G C A A G G T T G C A A C C T A G C T A C C T T G C T T G C T T G C T A G G T T G G T A G G T T G G T T G G T A C C T T G C T A G C A A C C A A G G T T G C A A C G A A C G T T G G A T G C A A C C T T G G T A C C T T G G T T C C T A G G A A C G A A G C T T C G T A G G T A G C A A G C A T G G T A G G T A C C A T G C T T C C T A G G A A G C T A C G T A G C A A C C T T G C T A C G A A G C T T G C A T G G T T G G T T C G T T C G A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T C C A A C C T A G G T A G C T T C C A T G G A A G G A A G C A A G C T T C G A A C G T A C G T T G G A T C G T T G C T A C G T T G G A T C C T T C C A T C C T T C G T A C C A A G G A T G G A T G C A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G A A G C T A C G T A C C T T G G A T C G T T G G T A G G T T C C T T G C A T G C A T G C A T C G T A G G T T C C T T C C A A G G T A G G T T G C A A G C A T C G A T G G A T G C A T C C A A C C A A G C T A G C A A C C T T C C A T C G T A C C T T C C A T C C A T C C A T G G A A G G T T C C A A G C T A C G A A C C A A C C T T G G A A G G T A C C A T C C A A C C T A C C A A G C T A C C T T C G T A G G A A C C A T G G T A C G A T G C T T C C T A C G T A G C A A G C T T G G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G A T C G T A G G A A G C A T G C A T C G A T C G T A G C T A G G A A C G A T G C T T G C A A C G T T G C T A G G T A G G A T C G T A C G T A C G T A C C A T G C T A C C T T C C T T G C A T C C T A C C A A C C T T G C T T G C A T C G T T G C T T C G A A C C T A G C A T G C A A G G A A C C T A G C A A C C T T C C A T C G A T G C A A G G T T G C A A G G T A G G A A G C T T G C T T C G A T C G T A C C T T G C T T C C T A C G T A G G A A G C A T G C T A G G A T G C A A C G T T C C A A G G T T C G A A C C T A G G T T G C T A G G T A G C T A C C A A G C A A C G A T C C T T G C T T G C T A G C A T C C T A C G T T C G A T C G A T G C T A G G T T C C A A G G A T G C T T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C A T C C T A G C T A C C A A C C T A G C T T G G T T G C A A G C T T G G T T G C T T G C A A C G T A G G T T G C A A C C T T C C T A G G T A G G T A G C A A C G T +177 A G C A A C G T A C G T T G C T A G C T A G C T A G C T A C G T A C C A A C G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A G C T T G G T T G C A T G G A A C G A A G C T T G C T T C C A T C C A A G C T A G G A A G C A T C G A T C G T A G C A A G C T T C G T A G C T T G C T A C C A T C C T A G C T T C C A T C C A T C G A T C G T T G C T A C G A A G C T T C G T A G C A A G C A A G C T A G C T T G C T A C C T A G C A A C G T A C C T A G C T A G C T A G G T T G G T A G G T T G G T T G G T A C C T T G C T A G C A A C C A A G G T T G C A A C G A A C G T T G G A T G C A A C C T T G G T A C C T T G G T T C C T A G G A A C G A A G C T T C G T A G G A T G C A A G C T A G G A A C G T A C G A T G C T A G C T A C C T T C G T A C G T A G G A A C C T T C G T A C G T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A C C A T G G T A C G T A G C T T C C T A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G G T A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G G A T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T G C T A C C T A G G A A G C T A C G T A C C T T G G A T C G T T G G T A G G T T C C T T G G A T G C A T G C A T C G T A G C T T C C T T C C A A G G T A G G T T G C A A G C A T C G A T G G A T G C A T C C A A C C A A G C T A G C A A C C T T C C A T C G T A C C T T C G A T C G A T G C A T G G A A G G T T C C A A G C T A C G A T C C A A C C T T G G A A G G T A C C A T C C A A C G A T G C T A C G T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C A A C G A A G C T T G G T A C C T T G C T T G C A T C C T A C G T A C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T A C G A T C G A T C G T A G C T T C G A A G C T T G C T A G G A T G G T T G C T A G G T A G C T A G G T A C G A T C G T A C G T A C C A A G C T A C C T T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T T C G A A C C T A G C A T G C A A G G A A C C A A G C A A C C T T G G T A C C A A C G T T C C T T G G T T G G T A C G A A G G A T G G T T C G T A C G A A C G T A G C T T C C T A G C A T C C A A C C T A G G T T G G A T G C A A G C T T C C T A C G T T C G T T C C T A G G T A C G A T G G T A G C T A G C A A G G A A C C T A C C T T G G T T G C T A G C A A C C A A C G T T G C A T C G A T G C A T C G T T C C A T G G T T C G T T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C A A C C T A G C A A C C A T C C T A G C T T G G T T G C A A G C T T G G T T G C T T G C A A C G T A G G T T G C A A C C T T C C T A G G T A G G T A G C A A C G T +178 A G C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T T C C A A C G A A G G A A G C A A C G A A C G A A C G T T G G T A G C A A G C A T G C A A C C T T G G T T G C A A C C A T G G T T C C T T G C T A G C A T C G T A C C T A C G T A G G A T C C A T C G T T G C A A C C T T C G A T G G T A G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G G T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C A A C C T T G C T A G G T A G C T A G G T T G G T T G C T A G G A T G C T A C C T A G C T T G G A A C G A A G G T T C C A A C G A A G G T A G G A T G G T T G C T T G C A A C C A T G C A A C C A A C G T A C G T A C G T A C G A A C C T A G C A A C C A T G G T A G G T A C C A T G C T T C C T A G G A A G C T A C G T A G C A A C C T T G C T A C G A A G C T T G C A T G G T T G G T T C G T T C G A A G G A A G G A T G C A T C G T T G G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T C C A T G C A A C G T T C C A T G C T T G G T A C C A A C G A T G G T A C G T T G C A A C G T A G G A A C G A A C C A A G G T T C C A T G G A A G G T T C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C C T T C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G C T T C G A T C C T A C G T A G G T T C C A T G C A A G C T A C C A T G C T T G C T T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G A A G C A T C G A A G C A A G C T T G C T T C C T T C G A A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A C G A A C C A A C C T T C C T A G C T A C G T T C C T A C C T A C C A A G C T A C C A T C G A A G C A T C C T T G C A A C G A T C G A T C C T A G C A A G C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T G G T T G C A A G G A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C G T T G G T A C C A T C C T T C C T A C G A T G G A T C G T A G G A T C G T T G G A T C G A T C C A A C C A A G G A A C C T T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T G G T A C C A A G C T A C G T T G C A T C G T A C C T A G G A T C G A T C G A A C G A A G C T A C C T A G C A A C C T T C C A A C C A T G C A A G G T T G C A T C G A A G G A A G C T T G C T T C G A T C G T A C C T T G C T T C C T A C G T A G G A A G C A T G G T T G G A T G C A A G C T A C G T A G C T A C G A A C C T T C C T T C G A T C G T A G C T A G C T T C C A A G C T T C G T T C G T T G C T T C G A T C C T A G C A T C G A A C G A A G C T A G C A T G C A A G G A T G C T T C C T A C C T A G C T T G C T A C C A A G C A T G G A T G C A T C C A T C C A A G G T A G G T T G C A A C G A A C C T A G C T T G C T T C C A A G G A A C G T A G C T T G C A A G C A T C G T T G C A A G C A A C C T A G C A +179 A C C T A G G T T C C T T G C A A C C T A G C T A G G T A G C T A G G A A G G T T G G T T C C T T G G T T C G A T G C T T G G T A G C A T C C A A C C T T G C T A G G T A G C A T G C A T G G T T C C T T G C T A C C A T C G A A C C T A C G T A G C A T C C A T C C T T G C A A C C T T C G A A G G T T G C T T C C A T C C T A G C A T C C A A C C T T C C T T G G A A G C T A C C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A G C T T G C T A G C T A G C T A G G T T G G T A G G T A G G A A G G T A G C A T G C T A C G A A C G T A G C T A C C A A C G A A G G T T G G A T G C A A C G T T G G A A G C A T G C T A C G A A C G T T G C T A G C T T C G A A G G T A G G A A C C T A G G A T C G A A C G A T G C A T C C T A G G T T C C A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A T G G T A C C T T G G T A C C T A G G A A G C T A G C A A C C T T G G T A G C A A G C T T C G A T G G T A C G T T G C A T C G A A C C T A C G T T G G A T C C T T C C A T C C T T C G T A C C A A G C T T G C A A G C A A C G A A G G A A C C A A G G T T C C T T G C A T G G T T G G A A C C T A G G T T G G A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G C A A G G A A G C A T G C A A C C T A C C T T G G A A C C T T C G A T C G A A C G A A C C A A G C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G A A C C T A G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C T T G G T T C C A A C G A A G G T T C C T A C G A A C C A A G C T A C G A A G C T A G C T A C G A T G C A T C G A A C C T A C G T T G C T T G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T T G G T A G C A A G C T T C G T A G C A T G C A T C G T A G G A T G C A A G G A T C C T T C G T A C C T A G G A A G G T T G C T A C C T T G G T T G C T T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A C G T A G C T A C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G C T T C C T T G G A A C G A T G C A T G C A A G G A A G G A A G G A A C C T A G C T T C G T A G G A T G G T T C C T T C C T A C G T A C C A A G C A T G G T T C G A T C C A T G C T A C C T A G C T A G G T T C C T T G G T A C G T T C G A A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A G C T T C G A T C G A A G C A T C G A T G C A A G G A A G G A T C C A A C G A A G C T T G C T A C G A T G C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C A A G C A T C C T T G C A T G G A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +180 A C C T A C G T A C G T T G C T A G G A T G C T A G G T A C G A T C C A A G G T T C C T T G C T T G C A A C G A T C C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A T G C A T G G T A G G T A G G A A G G T T G C T A C C T A G G T A C C A T G C A A C C T T G C A A G C T T C C T A G G T T G C T A G C A T C G T A G C A A G C A T C C T T C C A T G G A T G C T A C G A A G C T T C G T T G G T A G G A A C C T A G G T T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T A G G T T G G T T C C T A G G A T G G A A C G A A G G T T C C A A C C A A G G T A G G T T G C A A G G T T G C A A G C A T G C T A C G A A C G T A G G T A G G A A C C T A G G T A C C A A C G T A G G A A C G T A C G A T G C T A G C T A C C T T C C A A G G A T C C A T C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C G T A G G T T C C A A G C T T C G T T G G A T C C A A G C A A G C A A G C T A C C T A G C A T G G T T C C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T A C G T A G G T A C G T A C C T T G G A A C C A T G G T T G C A T C C T T G G A T G G T T G G A A G C A A C C A T C G A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C C A T C C A A C G A A C C A T C G A T G G A T G G A A G G T A G C T T G C T A G G A T G G A A C C T T C C T A G G A A C G T A G G T T G C T T G C T A G C T A G C A T C G A A G C T A G C A T G G T T C C A A G G T A C C T T G G T A G C A A G C T A C G A A C C A A G C T A C G T T G C T T G C A A C C T A C G A T G G T T G C T A C G A T C C T T C C A A C G T T C C T T C G A A C C A T G G A A G G T T G G T A C G T A G C T A G C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T C G A A G C T A C G T A G C T T G C T T G C T A C G T T G C T A C C T A G C T T G G T A C G T A C G T A G C T A C C A T C C T T C C T T G C A T C G T A C C A A G C T A C G T T G C A A G G T T G C T A C C A T C C T T C G A A G C A A G C T T C C A A G C T A C C T A G G A A C C A T G C A A G C A T G C A T G G T A G G A T G C T A G G T T G G A A G G A A G G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C G T A C C T T C C A T C C A T G C A T C G A T C G T A G G A T G G T T C C T A C G A A G C T T G C T A C C A T G C T A G G A A G C T A C C T T C C T A C C T A C G T A G C A A C C T T C C T A G C T T G C T T C C T A G C A T C G T A G C T A C C T A G C T T C G A A G C T A C C A A G G T A C C T +181 A G G A A C G T A C C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T G C T T G C T A G G T T C G A T C C A A C C T A G C A T G C A T C C T A C C T T G C T A G C T T G C T T G G A T C C T A G C T A C C A T C C T A C G T A G G A A G C A T G C A A C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C G A A G G A A G C T A C C A T C G A T C G T A G C A A C C A A C C A A C G T T G C A A C C T A G C A A C G T T G C T A G C T A G G T A G C T T G G T A G C T A G G A A G G T A G C A T G C T A C G A A C G T A G C T A C C T A C C A T G G T A G G T T G G T T C C T T G C A T C C A T G C A A C G A A G G T A G C T A G G A T C G A A C G A T G C A A G C A T G G A A C G A A C G A T C C A A C G T A G G T T C G A A G G A T C C T T C G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A T C G A A G G A T C G A T G G T A G C A T C C A A G G T A C G T T G C A A C C T A G G T T G C T T C G T T G G A T C C A A G G A A G C T T C G A T G G T A C G T T G C T T C G T T G C A A C G T A G G T T G G A A G C T T C C T T G G T A C C A A G C T A G G A A G C T T C C T A G G A A G C A A G G T T C C T A G C A A G G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G C A A G C T A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G A T C G A T G C T T C C T T G C T T G G T A G C T T C G A A G C A A G G T A C C A A C C A A G C T A G C A T G C T T C C T T G C T A C G A A C C T A C G T A G G T T C C T T C C A T G G T T G C T T G C T A C G A T G C T T C C A A G C T T C C A T G G T A C G A T G C T A G G T A G G T T G C A T G C T A C G T T C G A A G G T A G G A T G C A T C G A T C C T T C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C A A G C A T C C A T G G A A G C T A G G T A C C T A G C A A G C T A C C T A C G A T C G T T C G T T G C A A G G A A C G A T C G T A C C T A G G A A G G A A G C T A C G T A C G T A C C A T G G T T G C T A G G T A C G T T G G A T G C T A G C A T G C A A C C T T G C A T G G T T G C T A C C T T G C T T G C A A C C T A C G T A C C A T C C T T C G A T G G A A G G A A C C T A G G T T C C T T G C A A C C A T G C A T G G T T G G T T C G T A G G A T G C T T G G A T C G T T C G T A C C T T C C T T G C A A G G T T G G T A G G T T G C T T G C A A G C T T C G T T C C T A C C T T G C T T C C T T G C T A C G T T G C A A G C T A G C A A G G A T G G A A C C A T C G T A G C T A C C T A C C T A G G A T C G A T C G A A G C A T G C A T G C T A G G A A G G A T C G A A C G A T G C T T C C A A C G A T G C T A G G A A C C A T C C T A G G T A C C A A G G T T G C T A C G T T G C A A G C T T G C T T C C T A C C A A C G T A G C T A C C A A G C A T G C A T G G T A G G A A G C T A C G T +182 A C C T A G G A T G G T T C C T A C C T A G C A A G G A A C G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T T G G T A G C A T G C T T G C A A C C T T G C T A G C A T C C T T G G T A G G T T G G T A G C A T C G T A C C T A C G A T G G A T G G A T C C A T G G A A C C T T C G T T G G T T G G T T C C A T C C T A G C A A G G A A C C A T C C T T G G T A G C T A G C A T C G T T C G T A G C A T G C A A G C A A G G A T G C A A C C T A G C A A C G T A C C T T G C T T G C T A C G T T C C T A G C T T C C A T G C T A G G T A G C T T C C A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C T A C G A A C G T A G G T A C G A A C G A A C C T A G G A A C G T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A G G A A G C A A G G A T G C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G G A A G C T A G C T A C C T T G G T A G C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T T G G T A G G T T C C A T C C T A G C T A G G T A C G T A G G A A G C T A G C A T C C T A C G A T C C T T G G T T G G T T G G T T G C A A G C T A C G A A G G A A C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A A C G T A G C A A G C A T C C A A G C A A C C T T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T G C T T G G A T G G A T G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G T A C C T A C G T A C G A A C G A A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G T A C G T A G G T A G C A A C C A A G C T T G G A T C C A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A C G A T G C T A G C T T G G T T G C T A G G T T G C T A G G A A C G T T C C T A C C T A G C A T G G A A C C T T C G A T C G A A C G A T G C T A C G T A G C A A G G T T C G T T C G A T C G T T C G T A G C T T G C T T C C A T C G T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A C G A T G C A A C G T A C G A A G G T A C G A T C C T T C C T A G G T A C C T A C C T A G C T T C C T T G G T A G C T A C C T A G C T A G G T T C G T A C C T A G C T T G G T A G C T A G G A A G G A A G G T T C C A T C G T A C C A A G C A A C C T A G C A T C C A A C G A A G C T T G G T T G C A A G G A A G G A T C G A A C G A T G C T T C C A A C G A T G C T A G G A A C C A T C C T A G G T A C C A A G G T A C C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C A A C C A A C G T T C C T A G C T A G C A A G C A A C G T +183 A G C T A G G A T G C T T C C T A C C T T C G A A G G T A C G T A C C A A G G A T G C T T G C T T G G A A C G T A G C T A G G T A C C A A G C A T G G A A C C T T G C T A G C A T C G A T G G T T C C A T C G T A C G A T C C T A C G T A C G A T G C A T C C T T C G A T G C A A C C T T C G T A G G T T G C T A C C A T C C A A G C A A G G A A C C T T C G A A G G T A G C T T G G A A G C T T C G T A C C A A G C A T G G T A G G T T G C T A C C T A G C A A C G A T G C A A G C A A C G T A G G T T G G T A G G T A G G T A G G T A C G A T G C T A C G A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C T A C C A T G C T A C G A A C G T A G G T A C G T A C C T A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C G T T C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C T A C G T A G C T T C C T A G G T A G C T T C C A A G G T A C G T A G G T A C C T A G G T A C G T A G C A T C G A T C C T A G C A T C G T A C C T A G G T A C C T T C G T A C C T T G C A A G G T A C C T T G C T T C C T T C G T T G C T T C C A T G C T A G G A T G G T T C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G A T C C T T G G T A G G A T G G A T G C T T G C T A G G T A C G T A G G A A G G T T G C A T G C T A C G A T C G T T G G T T G G T T G G T T G C A A G C A T C G A T C G A T G C T T G C A A C C T A C C T T G G A A C C A A G G T A C C T T C C T T C G A T C C A A G C A T G G A A G G T T C C T T G C T A C G A T G G A A C C T T C C T A G G A A G C A T C C A A C C A T C C T A G C A T G C A T C G A A G C A T C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T A C G T A G C T T C G A A C C T T G C T T G G T T G G T T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C A T G G T T C C A T G C A T C C T A C C A A C C T T G C T T G C A T C G A A C C T A C C A T C C T T C G A T G G A A G G A A C C A A G C A A C C T T G C A A C G A T G C A A G G T A G C A T G C T T G C A A C C T A C G A T C G T T C G T T C C T T G C T T C C T A G G T A G C T T G C A T G G T T G G T T G C A A G C A A C G T T G C T A C G A A C C T A G G T T G C T A C G A A G C T A G C A A G C T T C G A T C C A T C G A A G C T A C G T T C C T A G G A T C C A T C C A A G C A T C G A T C G T A G G A T C G T T C G A A C G A A G C T T G C A A G C A T G C T A G C A A G C A A C C T A G C A A C C A A C C T T G C T A C C T T C C T A G G T T G G T T C C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +184 A G C T A C G T A C C T A G C A T G C T A G C T A G G T A G C A T C C A A G G A T G C T T G C T A C G T T C G A T G C T T G G T A G C A T C G A T C C T A C C T T G C T A G C T T G C T T G G A T C C T A G G T A G C A T C G T A C G T A G G A A C C A T G G A T C G A T G C A A G C T T C C T A G G T T G C T T G C A T C C T A G C T T G C A T G G T T C C T T G G T A G C T A C G A A G C T T C G T T G G A A G C A A G C A A G G A T G C T A G C T A G C A A C G T A C C T A G C T A G G A A G G T T G G T A C C T A G G T A C G T A C C T T C C A T G G A A C G A A G G T A G C A A C G A T G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A A G G A A C G A A G G T A C C A A C G A A G G A T C C A A C G A T G C T A C G T A G C T T C G T A C G T T C G A A G G T T G G T T G G A A G C T T G C A T G G T A G C T T C C T A G C A T G G A A G G A T C C A A G G A T G G A A C C T A C C T A C C A A C C A A C G T A C G A T G G T A C C A T G C A A C G T T G G A T C C A A G G A T C C T T G G T A G G T A C C T T G G A A G C T A G G A A G G T T C G T A G G A A G G T A C C A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A G G A A G G T T G G A A G C T T C G T T C G T A C C A A G G A T G C A A C C A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C A A G G T A G C T T G G A T G G T T G G A T G C T A C C T A G G T T G C T T G C A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A T C G A T G C A T G C A A C C A A C G T T G C T T G C T T C C A T C G A A C G A A C G A T C G A T G G A T G G A T G G T T C C T T G G A A C G A A G G T A G G T A C C T A G G T A G C A T C C T A G C T T G C T A G C T A G G A T C G T A G C A T G C A T G G T A C C A A G G T A G G T A G G T A G C A A C G T A C G A A G G A A G C T A C G T T G C T T G C A A C C T A C G A A G G T T G C T A C G A A C C T A G G A T G C T T C C T T C C T T C G T A G G A A C G T A G G T A C G A T G C T A C G T A C G A T G C A T C G T A G G T A G C A T G G A T C C T A C G A T C C T A G G A A C G A T G C T T G C A A C G T A C C A T G G T A G G A T G G T A C G A A C C T A C G T A G C T A C C T T C C A T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G G A T G G A A G G A A G C A T G G T T G G A T C G T T G G T T C C T T C G T A C G T T C G A A C C T A G C A A G G A T G G A A G C A A G G A A G G A A G C T T C C T A G C A A C C T A G G T A G C T A G C A A G G A A G C T T C C A T C G T T G C T T C C T A C C T A C G A T C C A T C G A A G C A T G G T T C C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T A G C T T G G T T G G A A G C T T G C T T C G T A G C A T C G T A G C T A G C T A G C A A G C A A G C T A G C A A C C T A G C T +185 A C C T T G G A T G C T T C C T A C C T T C G A A G G A A C G T A G G A A G G T T G C T T G C T T G G A A G G A T C C T T G G T A G C A T G C A T G C T A C C T T G C T A G C T T G C T T G G A T C C T A G C A A G C A T C G T A C G T A C G A T G G A T G C A A C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A T C C A T C G A A G G A A G C T A C C A T C G A T C G T A G C A A C C A A C C A A C G T T G C A A C C T A G C A A C G T T G C T A G C T A G G T A G C T T G G T A G C T A G G A A G G T A G G T A G C T T C C A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T C C T T G C A A G C A T G C T A C G A A C G T A G C T A G G A T C G A A G G T A C C A A C C T A G G A T C G A A C G A T G C A T C C T A G G T T C C A A G G A T C C A T C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A C G T A C C T T G G T A C C T A G G A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C A T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G A A C C A A C C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C C T T C C T A G G T A C C A T G G T T G C T T G C T A C G A T G C T T C C A A G C T T G C T T G G A T C C A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G T A C C T A C G T A C G A A C G A A C G A T C C T T C C A A C G T T G C A T G C T T C C A T G G A A G C T A G G T A C C T A G C A A G C T A C C T A C G A T C G T A G G A T C G T T C G A A C G A T C G T A C C T A G G A A C G A A G C T A C C T T G G T T G C T A G G T T G C T T G G T A C G T T G G A T G C T A G C A T G G A T C C A A G C A T C C T T G C A A C C T T G C T A G C A A G G T T C G T T C C A T C G T T C G A T G G A A G G A A C C T T C G T T G G T A G G A A C C A A C G T T C C T T G C T T G G T A C G A T G C A A C C T T C G T A C G A A C G T T G C T T G C A A G G T T G G T A C C T A G G T T G G A T G C A A G C T A C C T A G C T A G G T T C G T T G C T A G C T T G G T A G C T A G G A A G G A A C G A A C C A T C G T A C C T A G C T A C C A A G C A T C C A A C G A A G C A T C G T T G C T A G G A A G G A T C G A A C G A T G C T T G C T A C G A T G C T T C G A A G C A A C G T T G G T A C C A T C G T T C C T A C C T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G A A C C T T G C T A G C T A G C A A C G T A C C T +186 A C C A A C G T A C C T T G C T A G C T A G C T A G G T A C G T A G G A A G G T T G C T T G C T T G G A A C G A T G C A A C C T A G C T A C C T T G C A A C C T T G G T T G C A A G C T T G G T A G G T T G C T A C C A T C C T A C G T A G G A T G G A T G G A T C C A T G C A A C C T A C G T A G G T T G G T T C C A T C C T A G C A A G G A T C C A T C C A T G G A T G C T A C G A A G C T T C G T T G G T A G G A A C C T A G G T T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T A G G T T G G T T C C T A G G A T G G A A C G A A G G T T C C A A C G A A G G T T G G T T G C A A C G T T G G A A C C A T G C T A C G A A G G T T G C T A G C T T C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A G G A A G C A A G G A T G C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C G T A G G T T C C A A G C T T C G T T G C T T C C T A G G A A G C A A G G T T C C T A G C A T G G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G C A A G C T A G C A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G A T C G A T G C T T C C T T G C T T G G T A G C T T C G A A G C A A G G T A C G T A G C A A G C T A G C A T G C T T C C T T G C T A C G A A C G T A C G T A G G T T C C T T C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C T A G C A T G G T T G G A T G G T A C C T T G G T A C C A A G C T A C G A A G C T A G G T A C C A A C C T T G C A T G C T T C G A T C G A A G C T A C G A A C C T A G G A T C C T A C G T T G C A T C C A T G G A A C C T A G G T A C G A A C C T A C C T A C G T A C C A T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T A G G A A G C T T G G T T G G T A C C T A G G T T G C T A G G A A C G T T C C T A C C T A G C A T G G A A C C T T C G A T C G A A C G A A C C T T G C T T G C A T G G T T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G G T T C C T T G C A A C C A T G C A A G C A T G C A T G G A A G G A T C C A A G G T A C G A A G G T A C G T T C C T T G C A A C G T T G G A A G G T T G C T T G C T A G C T T C G T T C C T A C C T T G C T T C C T T G C T A C G T T G C A A G C T A G C A A G G A T G C T A C C A T G G A T G C A A G C A A C C T A G C A T C C A T C C A T G C T A G G T T C C A A G G A A G G A T C G A A C G A T G C T T C C A A C G A T G C T A G G A A C C A T C C T A G C A A C C A A G C T T G C T A C C T T G G A A G C T T G C T T C C T A G C A A C G T A G C A A C C A A C G T T C C T A G C T A G C A A G C A A C G T +187 T G G T T G G A T G C T T C C T A C C T T G C T A G G T T G G T A C C A A G G T A G G A T G C T A C G T T C C T A C G T T G G T A G C A T G C A T C C T A G C A T G G A A C C A T C C A T G G T T C G T T G C T A G C A T G C T A C C A A C G A A C C A T C G A T C G A T G C A A G C A T C G A A G G T T G C T T C C A T C C T A G C A T C C A T C G T T C C A T G G A A G C T A C G T T C G T T C G T A G C T T G C A A C C A A G G T T G C T A C C T A C C A A C G A T G C T A G C T A G C T A G G T T G C T A G C T A G G T T G C T A C G T T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C C T A C G T A G C A A G C A T G C T A G G T A C G A T G C A A C G T A G C T T C G A A C C A T G G A A C G T A C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A C C A A C C A A G G A A G G A T C G A A C C A A C C T A G G T T G G A A G G A T C G A T G G T A C C A A C C A A C G T T C C A T C G A A G G T A G C A T C C A A G G T A C G A T G G T A C G T A G G A A G G A A C C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G A A C C A A G C A A G C T A G G T T C G A T G C T T G C A T C G T T G G A A C G A A G G T T C G A A C G T A G G T T C G A A C C T A G C T A G C A T G C T A G C T T G C A A G C T A G C T A C C T T C C A T G G T T G G T T C G A A G C A A G C A T C G A A G C T T C C A T C C A A C C A A G C T T C C T T G G T T C C A T C G T T C C T A C G A T C C A T C C A T G G A T G C T A G C A T G G T A G C A T C C A A C G A A C C T A G C A A G C A A G G T T G C T T G C A A G C T A C G A T C G T A G C A T G C A T G G T A C C A A G G T A G G T A G G T A G C A A C G T A C G A A G G A A G C T A G G A A G C T T G C A A C C T A G G A T G G T T G C T A G C A A C C T A G G A T C G T T G C T T C G A A C C A T G G T A C C T T G G T A C C A A G G T T C C T A G G A A G C A T C G T A G G A T G C T A G G A A C C T T C G T T G C T T C G T A G G T T G C T T G G T T G G T T G C T A G G T T G C T A G G T A C G T T C C A A G C A A G C T A G C T A C C T A G C A T G G T A C C A A G C T A C G T T G C A T C G T A G G T T C C A A C G T T C G T A G G A A G G A A C C A T G G T T G G T A G G A A G C A T G C A A G C T T G G T T G G T A G G A A G C T A C C T T G G A A G G A A C G T T G C T T C C A A G C A T C C T A C C T A G C A T C C T T G G T T G C T T C C A A C C T A G C A A C C T A G G T A C G A T G G A A G C T A C C A A G G A A G C T T C C A T C G A T G C T A C C T A C G A T G G A T G G A T C C A T C C T A G G T A C C A T G G T T G C T A G C T A G G T A G C T T G C A A C C T T G C T T G G A A C C A A C C T T C C A A C C A T C C T T G C T A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A C C T A G G A A C C T A G C T A C C A A C C T A G C A +188 T G G T T G G A T G C T T C C T A C C T T G C T A G G T T G G T A C C A A G G T A G G A T G C T A C G T T C C T A C G T T G G T A G C A T G C A T C C T A G C A T G G A A C C A T C C A T G G T T C G T T G C T A G C A T G C T A C C A A C G A A C C A T C G A T C G A T G C A A G C A T C G A A G G T T G C T T C C A T C C T A G C A T C C A T C G T T C C A T G G A A G C T A C G T T C G T T C G T A G C T T G C A A C C A A G G A T G C T A G C T A C C A A G C T A C C T A G C T T G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A T G G T A G G T A C C A A C G A T G G T A G G T A C C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C T T C G A A C C T A G G A A G G T A G G A A C G T A C G A T G C T A G C A A G C T A C G A A G G A T C C A T C G A T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T T G C A T G C A A G C A T C C T T G G A A G G T A G C A T G G T A G C T A G G T A G C A A C C A T G G T A G G T A G C A T C G T A C C A T G G T A C G T T G C T A C G T T G C T A C G T A G G T T G G A A G C A T C C T T G G T A C C A A G C T A G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C T T C G A T C C T T G G T A C C T A C C T A C C A A G G T A G C A A G C T A C C A T C G T T C C A T G G T T G G A A G G A A G C A T G C A T C G A T G C A T C G A A G C A A G C T A G G T A G C T T C G T T G C T T C C T A C G T A C C T T C C A T G G T A G G T A G C T T G G T A C G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A C C T A C G A A G C T A G G T A C C A T C C T T G C A A G C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G G A A C G T A G G A A C G A A G G T T C G T A C C T A C G A T C G T T C G A T G G T A C G A T C G A T C G A T C C T A C G A A C C T T G C T A G G A T G G A T G C A A G G T T G C T T G G T A C C T A C C A T G C T A C C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C A T C G A A G C A A C C T A G C A A G C T T G G T A G G A A C C A A C G T A G G T T G C A T G G A A G G A A G C T T G C T T C G A A G G T A G G A T C C T T G C A A C G T T C G A A G C T A G C A A G G A T G C A A G C T A C C T A G G T T C G T T C G T A C C T A G C T A G G A A G C T A G C A A G C T T C C T T C C T T C G T T G C A A C G T T C C A A C G T T C C A T C C A T G C T T G G A T C G A A C G T A G G T T C C T A C C A A G G A A C C T A G C A T C G T T G G A A C C A T G C T T C C T T C C A T C G T T C C T A C G T T G C A A G C T T G C A T G C T A G C A A C G T A G C A T G C A A G C A A C G T A G G T A G G T T G C T A G G T +189 A C C T A G G T T C C T A G C T A C C T T G C T A G G T T G G T T C C A A G G T T G C T T G C T T G G T T G G A A G C T T G G T A G C A A C C T T G C A A C C T T G G T A G C A A C C A T C G T A G C T T C C T A C C T T C G T A C C A A G G A A G C A T G G A A C G T T G C A A C C T T C G A A G G T T G C T A C C A T C C A A G C A A G G A A C C T T C C T T G G T A G C A A G C T A G G A T C G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C G T T C C A A G C T A G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A A C G A A G C T T C C T A C C A T G G T T G G T T G C T T C C T T G C A A C C A T G C T A C C A A C G T A G G T T G C T T C G A A G C T A G G A A C G T A G G A A C G T A C G A T G C T A C G T T C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C C T A G C T T C C T A G G T A G C A T C G A A C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T T G G T A C C A A G C A T G G A T G C T T C C T A C G A A G C A A G G T T C C T A G C A T C G T T C C T A C G A A G G A A G C T T G G T T G G T T C C A T C C T A G G A A G G T A C C T A G G A A G C A T G C T T G G T A C C A T C C A T C C A T G G T A G G A A G G A A G C A T C G A A G C T A G C T T C G A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C G T T C C A T C C A T G G A T G C T A G C A A G G T T C G A A C G T A G G T A C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A C G T A G C A A G C T A G G A A G C T A G C T A G G T T G C T A C G A T C C T T C G A A G G T T G C A A G G A T C C T A G G A T C C T A G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G A A G C T A G G A A G G A T G C T A G G A T G G A A C C T A G G T T G C T T C G A A C C T T C C T A G G T A G C T A C C T T C C A T G C A T G G T A C C A A G C A A C G T T G C A T C G T A C C T T C C A T C C T T C G T T G G A A G G A A C C A T G C T A C C T T G C A A C C A T G C A A G G T T G G A T G C T T G C A A C C A T C G A T C G T T C G T A C G A T C C T A G C A A G G T A C G A T G C T T G C A A G G A T G C A A G C A A C C A A G C T A C G T T C C T A G C T T G C T T G C T A G C T T G G A A C G A A C C T T C C A T C G T A G C T T C C T T C C T A C C T T C G A T C G A T C C T A G C T T C G A A G C A T G G T A G C T A C G T T C C A T C C T A G C T T G C T T G C A A G G A A C C T A G C T A C C A A G C T T G C T T C G A A G C A A G C T T G C T T C C T A G C A A C C T A G G T T G C A A G C A A C C A T G C A A G C A A C C T A G C A +190 A G C T A G G T T C G T A G C T A C C T T G C A A G G A A C G T T C C A A G G T T G G T T G C A A C G A A G G A A C C A T G G T A G C A T G C T T C C A A C C T A G G T A G C A T C C A T G G A T C G A T C G T A C C A T C G T A C G T A G G A A G C A T G C T T C G A T G C A A C C T T C G T T G G T T G C T A G C A T C C T A G C A T C C A T C C T T C C A T G G A A G C T A C C A A G G A T C G T A G C T T G C A A G C A A G G A T G C T A G C T A G C A A C G T T C C T A G C T A C C T A G G T T C C T A G G A A G G A A G G T A C C T A G C A A G C A A C C T A G C T A C C A A C G A A G G T T G G A T G G T T G C A T G C T T C C A T G C A A C C A A G G T A C G A T G C T A C G T A G G T A C C A A C G T T C C A T C G T A C G A T G C A A G C T A C C A T C C A A G G A T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G A A G C A A G C T A G G A A G G T A C C A A G C T A C C A T C C A A G G T T G G A T G G T T G C T A G G T A C C T T G C T A G C A T C C T T G G T A C C A T G G T T G G A T G G T T C G A A G G A A G C A A G C T A C C T T G C A T G G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T A G C T A G C A A C G T A G C A A G G T A C C T T G C A T G C A T C G T T G G A T G C A A G C A T G G T T C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A T C G A A C C T A C G T T C G T A G C A T C G T A G C A A C C A T G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G C A A G C A T G G T T C C A A C G A T G G T T C G T A G C A A C C A A C G T A C G A A G G A T C G T A C C T T G C T T C G A A G C T T C G A T G G T T C G A A G G A T C C T T C C A A C G T T G C A A G C A T C C A T C G A A C G T T G G A T G C A A G G T A C C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T A G C T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C A T G G A T C C T A C C A A C C T A C G T T G C A A G G T T G C T A G C A T C C A T G C T A G C T T G G A A C C A A G C A A C G T A G C A A C G A T G C A A G C A A G G A T G G A A G G A A C C T A G C T T C G T A G G A T G G A T C C T T G C A A C G T T G C T A G C T A G G T T G C A A G C A A C G T T C C T A G C T A G G T T C G T A G C T A C C T A G C A A G C A T G C A A G G A T C G A A C G A T C G T T G C A A C C T A C G T T G C T T G C A T C C A A G C A T C G T T G C T A G G A T G G A T C C T A C G A T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C T A G G T T G C T T C C T A G C A T G C T A G C T A C C A A C C A A C C T A G G T A G G T A G C A A C G T +191 T C C T A C G T A C G T T G C T A C C T T G C T A G G T A G G T A C G A A G G T T G C T T G C T T G G A A C G A A C C T A G G T A G C A T G C T T G C T A G C A T G G T A G C A A C C A T G G A A C G T T G C T A C C T T G C T A G C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A A C C T T C C A A C G A A G C T A G C A T C G T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G G A A C C T T C C T T G C T A G C A A G G T T G G T A G G T A G G A A G G T A G C A T G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A C G T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A T C C A A C C A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T A C G T A G G T A C G T A G C A A G G A A G C A T G C T T G C A T C C T T C C T A G G A A C G A A G C T A C C A T G C A T C G A T G C A T C C A A C C A A C C T A G C T A G G T T C G A T G C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G G T T C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G G T T C G T A C G A T G G A T C G T A G G T A G C A A G G A T C C T T C G T A G C T A C G T A G C T T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A G C A T G C A A C C A T G G A T C C T A C G A A C C T T G C T T G C A A G G T T G C T T C C A T C C T T C G A A C G A A G C T A C C T T G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C A A C G T T G G T T C G T A C C T T C C T T G C A A G G T A G C T A G C A T C G A T G C T A G C A A C G T T C C T A C C T A C G T A C C T T G G A A G C T A G G A A G C T A C C A A G G T T C G T A C C A T C G T T G C T T C G A A C C T A C C A A C C A T C G A T C C T A G G T A C C A A G G A T G G T T C C T A C G T A G G A T C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C G T T G G T A G C T T G C T T C C T T G C T A C G A T G C T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +192 A C C T A G G T T C C T T G C T A C C T T G C T A G G A A G C T A C G A A G G T T G C T T G C T T G G T T C G T A C C T A G G T A C C A T G C T T G G T A C C T T G C T A G C A T C G A T G G T T G G T T G G T T C C T T G C T A C C A A C G A A G C T T G C A A C C T T G C A A C C T T C G A A G G T T G G A T C C A T C C T A G C A T C C A A C C T T C C T T C G A A G C T A C G A A G C T T C G T T G C T A G C T A G C A A G G A T G C A A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T C C A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A C C A T C C A A G G A A C G A A C G T T G C A T C G T A G G T A C C A A C G T T G G T A C G T A C G A T C C A T C G T A G C A A G C T A C G T A G C A A G G T T G G A T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T A G G A A C C T A G C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A G G A A G G T A G G A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G C A A G C A A C G A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T A C C A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G C T A G G T A C G T A G C A A C C T A C G T A G C T T G G T A C G T T G C T T C G A T C C T T G G A A C G T T G C T A C G A A C C A A G G A T G C T T C C T T C G A A C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T A C C T A G G A A C G A T G C T A C C T T G G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G T T G G T T C C A T C C T A G C A A G C T T G C T A C C T A G C T T G C T T G C A A C C A T G C T A G G T T G C A T G G T A C G A A G C A T G G T A C C A A G G T A C G T T G C T T C C A A G C A T C C T A C C T A G C T T G C T T G G A A G C T A C C T T G C T A C G T T C C T T G G T T G C T T G C A A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T G C T A G C A A C G T A G G T T G G A A C G T T C C T A G C T A G C A A C G T A C C T +193 A G C T A G G A T G C T A G C T A C C T T C G A A G G T A G G T A C C A A G G T T C C T T G C T T G G A A C G A A G C T T G G T A G C T T G C A T C G T A G C T T G G T A G C A T G C T T G G A T C C T T G C T A G C A T C C T A C G T A G G A T G C A T G C A A C G T T G C A A G C A T C C T T G G T T G C T A C C A T C C T A G C A A G G A T C C A T C G A A C G A T G C T A C G A A G C T T C G T T G C A A G G A A C C A A G G T A G C T A G C T A C C A A C C T A C C T T G C T T G C T A G G T T G G T A G C T A G G A T G C T A C G T A G C T T G G A A C C A A G G T A C C A A C C A T G G T A G G T T G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C C A T G C A A G G T T C C T A C G A A C G A T C C A A C G T A G C T A C C A A C G A A G G A A C G T T G G A A C G A A G C T T G C A T G C T T G C T T C G A A C C A A C C A A G C A A C C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C G A A G G T A G C T T G C A A G G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T G G A T G C A A C G A A G G A A C C A A G C T A G C T T G C A A G G T T G C T A C G A A G G T A G C T T G G T T G C A T G G A T G C T A C C T A G C T A C C T A G C A A G G A A C C T T G C A T C C A T C C T T C G T T G G T A G G A T G G A A G C A T C G A T C G A T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T T C G A A C G T A C G A A G C A T C G A A G G T A C C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A T C C A A G G T A C C T T G G T A C C A A G C T T C G T T C G A A G G T A C C A T G C A T C C A A C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T A G C A T C C A T G G A A C G T T G G T T G C A A C C A A G G T T G C A T G G A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A G C T T G C T A G C T T G G T A C C A T G G T T G C T A G G A A C G A T C C T A G C T A G C A T G G T A C C T T G C A T C G A A C G A A C C T T G C T A G C T A G G A T G C T T C C A T C C A T G G A A G C A A G G A A G C T A G C T T G C A A G C A A C C A T G C A A G C T A G G T T G G T A G G A T G G A T C G T T C G T A G G A A C G T T C C T T G C A A C G T T G C A A G C T A G G T T G G A A G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T A G G T A G C A T C C A A G G A T G G A A C C A T C G T T G C A A G C A A C C T A G G A T G C A T C G A A G C T T G G T T G C A A G G A A G C T T C C T A C C T A G G A T G C T A C C T A G C T T G G A A C C A T C C T T C C A A C C A A C C T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C G T A G C T T G C A A G G A T C C T A G C T A G G A A G C T A G C T +194 A G C T A G G T A C G T T G C T A C C T T C C T A G G T A G G T A C G A A G G T T C C T T G C T T G G A T G G A T G C T A G G T A G C A T G C A A G C T T G C A T G G T T G C A T G G A A C G A T C C T T C C T A C C A A G G T A G C T A C G T A G C A T C G A T C C T T G C A A C C A T C G T A G G T T G C T T C C A T C C A A C C T T C C A T C C A T C C A A C G T A G G A A C C T A G G T T G G T A G C T T G C A A G C A A G C T T G C T A C C T A C C A A C G T T G G A A G G T A C G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C G A T G C T A C G A A C G T A G G T A G G A A C G A A C C T A C C A A G C A T G G A A G G T A C G A T G C T T C G T A G C T T C G A A G G A T C C A T C G A T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A G G T A C C A A G G A T C G T T C C A A C G A T C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C A T G G A T C C T A C C T A G G T A C C T A G C A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C T A C G A T G C A A G G A T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C G A A C C T A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C C T A C G T A G C A A C C T A G G A A G G A A G G T A C C A T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A A G C A T G C A A G G T A C C T A G G T A C G T T G G A T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A G G A A G G A A C C A A G C T T G G T A G G A A C C A A C G T T C C T T G G T T G G T A G G A A G G A T G C A T G G T A G G A T G G T T C C T T C G T A C G T A G C T A G C A T G G T T G G A T G C A A G C T A C G T T G C T A C G T T C C T T G G T A G C T T C G T A G C T A C C A A G G A A G C T A C C A T C G T T G C A A C C T A C C T A C G A T C G A T C G A A G C A A G G T A C C A T G C A T G G A T C G T A C G A T G C T T G C T A C C A T G C T T G C A A C C A T C C T A G C T T C C A A G C T T G C T T C C T T C C A A G G T T G C T T C C A A G G A T C G A T G C T A G C T A G C T A C G T A G G T A G G A A G G T A C C T +195 A C G T A C G T A C G T A G C A A G G T T C C T T G G T T G G T A C C A A G G T T G C T T G C T A C G A A C G A A C C T A G G T A G C A T G C T T C C T T G C A T G G T A G C T T C C A T G G A A G G A T G G T A G C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C G A A G C T A C C A A C G A A G G A A C C T A G G T T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T A G G T T G G T T C C T T G C A T G G A A C G T A G C T T C C A A C G A A G G A A G G A T G C T T C C T T G C A A C G A T G C A A C G A A C G A A C G A A G G A A C G A A G G T A G C A A C G T T C C T T C G T T G G A T G C T T C G T T C C T T C G A A G G A A G G A A G G T T G G A T C G A A C C T A G C A T G G T A G C T T C G T A C C A A C C A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T A G G T A G C A A C C A T C G T A C C T T G G T A C G T T C G A A G C A A G C A T G G T A C C T A C C A T C C T T C G A T G G T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T G G T T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G C A A C C A A G G T T C G T A G C A T C G T T C C T A C G T A G G A A C C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G G T A C C T A G C A T G C A T C C T T G G A T G C A A C G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T A C G A T C C A T C C A T G G A T G G T T C C T A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C A T C G A T C C T A G G A T G C T T G C T T C C T T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A A G G T A C C A T G G T A C C T T G G T A C G T T G G A T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G A A G C A A G C T T G G T A G G A A C C A T G C A A G G T A G C A T G G A A G G A A G G A T G G T T C G T A G G A T G G T T C C T T C C A A C G T T G G T A C C A A G G T T G G A T G C A A G C T A C G T A G C T T C G T T C C T A G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A T C G T A C C A T C C A T G C T T G G A T G G T A G C A T G C T A G C T A C G T A G C T T G C T A C C T T G C T T G C A A C C A T C C T T G C T A C C A A C C T T C C A T C G T T G C T A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +196 A C G T A C C T A C G A T G C T A C G T T G C T A G G T A G C A T C C A A G G A T G C T T G C T A C G A T C G A T C C T T G G T A C C T A C C T T G C T T G C T T G G T A C C T T C C A T C G T T C C T T G C A A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G C T T C C A T C G A A C C T A G G T A G C T A G C A A G C T T G C T A C C T A C C A A C G T T G C A A G C A A C G T A G C T T C C T A G G T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T A G G A T G G T T G C T T G C A A C C A T G C A A G G A A C G A A C G T T G C A T C G T A G G T A C C A A C G T T G G T A G G T A C G A T C C A T C G T A G C T T C G T T C G A A G G A A C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G C T A C G T A G C T T C C T T G G T A G C A A C C A A G G T A C C T T G G A A C C T A G G T A G G T T C G T T G C T A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A G G A A G C A T G C A A G C A A C C A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G G T A C C T A G G A A G G T A C C T A G C A T G C A T C C T T C C T T G G T A G G A A G G A A G C A T C G A A G G A T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A T C G A A C G T A C G A A G C A T G G A A G G T A C C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G C T T C C T A C G T A C C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T A C C T A C G T A G C T A G C T A C G T A G G A T G C A A G G T T G C T A G G T A C G T T C G T T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C A A G G A T G C T T C C A T C C A T C G A A G G A A G C T A G C T T G C T A C C T T G G A A C G A T G C A A G C T A G G T T G G T A G G A T G C T A C G T T G G A A G G A A G G T T C C T T G C A A C G T A G C T A G C A T G C T T G G A T G C T T C G T T C C T A G C T A G G T T C C T A G G T T G C T A G G T A G C T A C G A A G G A T G G A A C C T T C G T T G C T A G C A A C C T A G G A T G C A T C G A A G C A A G G T A C C A T G C A T G C T T C C T A C C T T G C T T G C T A G C T T C C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +197 A G G A A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T T C C T T C G T A G G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G G T T G G T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G G A T G G T A G G T T G G T A G C T T G C A A G C T A G G T A G C T A G C T A G G A A C G T T C C T A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A C G A A G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C C T A C G T A G G A A C G T T G G A A C G A A C G A T C C A T C G T A G C T A C C A A G G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A G G A T G G T A C G T A G C T T C C T A G G T A G C T T G G A A G G T A C C T T G G T A C C T A G C A A G G T T C G A A G G A A G G T A C C A A G G A T G C A A G G T A C G T T G C A A C G T A G G A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C G T T G C A A G C T A G C A T G C T A G C T T C C T T C C A A G G T A G G T T G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G A A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T C C T T G G A A C C A T G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T A G C T T G G T A G C T A C C A A G G A A G C T A C C A T C G T T G C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C A T G C T T G G A A C C T A C C T A G C T A C C A T C G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +198 A C C T A C G T A C C T T G C A T G C T T G C T A G G T A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T A C C T T G G T A G C T T G G T A C C T T C C A T C G A A G C T T G C T T C C A T C C A A G G T A G G A T G C A T G G A A C G T T G C A A G C A T C C T T G G T T G C A A C C A T C C T T G G A A G G A A C C T T C C A T G G A A G G A T C G A A G C T T C G T A G C T T G C T A G C A A G G T A G C T A G C T A G C A A C C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G A A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A C G T A G G T A C C T A C G A A G G T T G G A A G C T A G G A A C G T A C G A T G C A A C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G T T G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T G G A A C G A A G G T A C C A T C G A T G C T T G G A T G C T A C G T A G G T A C G T T G G A T G C T A G C T A C G A T C C T T C G T T C C T T G C A A G C A T G G T A C C A T G G A A G G T T G C A T G C T T C C A A G C T T G C T T G C T T C G A A G C A A C C T T C C T T C G A T G G T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A G C T A G C T T C G T A G C A A C G T T C C T T C C T A G C A T C C T A G C T T G G T T C G T T G G A T G C T A C G T T G C T A C G T T C C T A G G T T G C A T G C A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A G C A A C C A A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C T T G C T A G G A A G G A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +199 T G C T A G G A T G C T T C G A T G G A T G C T A G G T T G G T A C C A A G G A T C C T T G C T T G G T T C G A A C C T T G G T A C C A T C C T T C C T A C C T T G G T A G C T T C C A T G G A T G G T T G G T A G C A T C G A A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C T A G G T T G G T A C C T T C C T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C T A G G A A C G T T G G A A C G A A C G A T C C A A C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T C G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G C T A C C A A C G T A G G T A C C A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C T T G G A T G C T T G G A T G C T A C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A A C C A A G G T A C G T T G C T T C C A A G C A T G C T A C C T A G C A T C C T T G C T T G C T A C G T A G C T A G G T T C G T A C G T A G C T A G G T A G C T A G C A A G G A A G C T A C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C T T C C T T G C T T C G T T G C A A G C T T G G T T G C T T G C T A C C T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +200 A C C T A G G T A C G T T G C T A G C A T G C T A G G A A G C T A C C A A G G A T G C T T G C A A C G A T G G A T G C A T G G T A G C A T C C T T G C A A C C T T G C T A G C A T C C A T G G A A C G T T G C T A C C T T G C T A C C A A C C A A G C T T G G A A C G A T G C A A G C T T C G T A G G T T G G T T C C A T C C T A G C A T C C A T C C T T G C T T G G T A G G A A C C A T G G T T C G T A G C T A G C A A G C A A G G A T G C A A G C T A G C A A C G T T C C T A G C T A C C A A G G T T G G T A C C T T C C T A G G T A C C T A G C T T G G A A C C A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C C A A G G A T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T G C A A C G T A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G T A G C T A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A G C T A C G A A C C A T G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C C T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A G G A T G C T A C C T T G G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T A G G A A C C A T G C A T G C A T G G A T G G A A G G A A G C A T G G T T C G T A G G A A C G T T C C T T C C A A G C A T C C T A G C T A G C A T G G A T G C A A G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A C C A T G C T T C G T A C G A A G G T T C C A A C C T T G C T A G G A A G C A A C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G C A A C C A A G G A T C C T A G C T A G G A A G C T A G C T +201 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C T T G C T T G C T A C C T T G C A T G G T A C C T T G G T A C C A T G C T A C C A A G G T A C G A T G C T T C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A C C A A G C T T G G T A C G T A C C A A C G A A G G T T G C T A C C T A G G A T G C T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T C G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A C C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C T T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A G G A A G C A T G C A A G C A A C G A A G G A A C C A A G G T T C G T A G G A A G G T T G G A A C C T A G G A A G C T T G G T T G G A T G G A T G C T A G C T A G G T A C C T A G G A A G C A A C C T A G C A A C C A A C C T T G G A T G C A A G G A A G C A A G C A T C G A T C G A T G C A T G C A A C C A A C C T T G G A A C C A A G G T A G C A A G G T A C G T T G G A A C C T A G C A T G G T T C C T T G G T A C G A A C C A A C C T T G C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T C C A T G G T A C G A T G C T A G G T A G G T T G C A T G C T A C G T T C G A A G C T A C C T T G C T T C G A A C C T T C G T T G C T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T T G C T A C G A A G G T T G C T T G G T T G G A T G C A T C C T T G C T T G G T A C G A A C G T A G C T A G C T T G G T A C C A T G C A T C C T A C C A A C C T A C G T A G C T T C G A A C G T A C C A T C C T T G G A A G C A A G C T A G C A A G C A A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A G C T T C G T A C G A A C G T T C G T T C C T A G C A T C C T A G C T A G G T T G G T T G C A A G C T A C C T A G C T A G G T T C G T A G C T A G C A T G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G G A T C C A T C C A A G C A T C G T T G C T A G G A T G G A T C C T A C G A T G C T T G C A A C C T T G C T A G G A A G C T A C C T A G C T A C C A A G G T T C C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T C C T A G G T A C C T A G C T A G C A A C G T A C C T +202 A C C T A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T T C C T T C G T A G G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A C C T T C G T T G G T T G C T A G C A T C G T A G C A A G G A T C C A T C G A A G G T A G G A T C G A A G C T T C G T T G C A T G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T T C C A T C G T A C G A T G C A A G C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C T T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G C T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G C T A G G T T G C A A G C T A C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C A T G C T A G G A A C C T T C G A T C G A A C G A T C C T T G C T A G C A T G G T T G C T A C G A T C G T T C G A A C G A A G G T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G A A G G A A C G A A C C T T G G T A C G A A C G T T G C T T C C T A C G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C C T A C G T T G C A T C G A T C C T A G G T T C G A A C G A T G C T A G C T A C G T A G G A T G C T A C C A T G C T T G C A A G C A A C C T T G C T A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A C G A A G G A T C C T A G C T A G C A A G C T A C G T +203 A G G A A C G T A C C T A G G A T G G A T G C T T G G T A C C A A C G A A G G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A T C C A A G C A A C C T A G C T A G C A A G C A T G G A T C C T T G C T T C C T T G C T A C C A A C G T A G C T T G C T A C G T T G C A A C C T A C G A T G G T T G C T T G C A T C G T A G C A A G G A T C C T T C C A T C G A A G G A T C G A T C G A T C G T A C C T A G C A A G C A A G G T A G C T A G C T A G G A A C C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A A G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A C G T A G G T A C C T A C G A A G G T T G G A A G C T A G G A A C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A G G A T G G T A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A A G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A C C A T C G A T G C T T G G A T G C T A C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G A T G C A A C C A A G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T G G T T C C A T G G A A C C T A G C A A G C A A G C A A G C T A C G A T G G A A C C T T C C T A G G T A G C A T C C A A C C A T C C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G A T C C T A G C A T G G T T G C A A G G A T C C A A G G A T G C T T C C T T C C T T C C A T G G T T G G A T G G T A C C A A G G T T C C T A C G A T G C A T C G T A G G T A G C A A C G A T C G A T C G T A G C A T C G A A G C T T G C T A G C T A C G T A C C A A C C A T G C T T G G T A C G T T G G A T G C A T G C T T G C A A C C A T G G A T C C T T G C A A C C T T G C T T G C A A G G T T G C T T C C A T C C T A G C A A G C T T G C T A C C T T G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G A A G G A A C G A A C C T T C G T T C G T A C G A T C C T T C C T A G G T T C C T A G C T A G C A T C C T T G G A A G C T A C C T T G C T A C G T T C C T T G G T T G C T T G C A A G C T A G G A A G G A A G C T T C C A T C G T A G C A A C C T A C C T A C C A T C G A A G G A A G C T A G G T T G C A A G G T T C G T T C G A A C G A A C C A T G C T A C C T T G C T A G G A A C C A T C C T T G C T A C G A A G C T T G G T T C C T T C C T A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +204 A G C T A C G T A C C T T C C T A C G T T G C T A G C T T C G A A C C A A G G T T G C T T G C A T G G T T C G A A C C T T G G T A C C A T G C A T G C T A G C T T G G T A G C A T G C A T G G T T C G A T G G T A G C A T C C T A C C T A G G T T G C A T C C T T C G A T G C A A G C T T C C A A G C T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G G A A C C T T G C A A G G T T G G T A G G T T G G T A G G T T C C A T G C T A G G A T G C T T G G A T G G A A G G T A C C A A C G A T G C T A C G A A G C T T C G T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C G T A C G A T G C A A G G T A G G A A C G T A C G A T G C A T C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T G C T A G C A T C C T T G G A A G G T A C G T T G G T A C G T T G G T A C G T A G G A A C C T A G G T A C C A A G C T T C C A T C C A A G C T T G C A T C G T T G C A A G G T T G G T T G C T T C C T T C G T T G G T A G G A A G C A T G C A A G C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T T G G A A C G T A G C A T C G A T G G T T G G A T C C T A G C T A G C T A C C T T G G A T G C T A G C T T C G A T G C T T C C A T C C A A G G T A G G T T G C A A C C A T G G A T C G A T C C A T C C A A G C A A G C T T C C T T G C T T C C A T G C A T C G T A C C T A G C A A G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G T A C C A A G G T A G C T T C C T T G C A T G C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A C C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G C T T C G T A C G A T G G A T C G T A G G T A G C A A G G A T C C T T C G T A G C T A G G A A C G A T G C T A C C T T G G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A C C T A C G T A C C A T C C T T C G A A G C A A G G T A G C T A G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C A A C G T T G G T T C G T A C C T T C C T T G C A A G G T A G C T A G C A T G C T T G G T T C C A A G C A A G G T A C C A A G C T T C C T A G G T T G C A T G C T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C G A A G G A T C C A A G G T A C C A T C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C C A T C C T T C C A T G G T T G C A A G C T T G C T T C C T A G C A A C G T T G C T A G G A A G C A A C G T T G C A A G C A A C C T A G C A +205 A G G T T G G A T G C T T C C T A C C T T C G A A G G T A G G T A G G A A G G T T G C T T G C T A G G T T C G A A C C T A G G T A C C A T G C A T G C T A G C A T G G T A G C A T C C T T C G A A G G A T G G T A C C A T C C T A C C A A G G A A G C A T C C T T C G A T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C A T G G T A C C A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C G A T G C A A G C T T G G A A G G T A C G A T G C A A C C T A G C T T C G T T C G A A C G A A C G T A C G T T G G A T C C T T G C A T G G T T C C A T G G A A G C A T C G A A G G A T G G T T C G T A G G A A C C T A C C T A G C T A C C A A G C T A G G A T G G T A G C A T G C A A C C T T C C A T G C A T G G T A G C A A C G T A G G T A C C T T G G T A C C A A G C A A G C T A G C A T G G A T G G T A C C A T C G T A C G A T G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A C C A A C G A A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A C C A T G G A T C C T A C G T A G C A A C G T A G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G A A C C A T G G A A G G A A C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C C T A C G A T C G A A G C T T G C A A G G T A C C T T G C T A C G A A G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G C T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T G C T A C C T T G C A T C C A T G G T A C G T T G G T T G C A A G G T A C C T A C G A T G G A T C G T A G C A T G C T T C G A A C C T T C G T A C C T A G C T T G G A T G C T T G C T T G G T T G C T T C C T T G C T A G G T A C G T T G G A T G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A G G A A G C T A G C T A G C A A C C T T G C A A C C A T G C A T C C T T G G A T G G T A G G A A G G A A G C T T C G T A G G A A C G T T G C T T C C A A G C A T G C T A C C T A G C A T C C T T G C T T G C T A C G T A G C T A G G T T C G T A C G T A G C T T G G T A G C T A G G A A G C A A C C T A C C T T C G T T G C A T C C T A C C A A C G A T C C A T C G A A G C T T G G A T G C T A C C A T G C T A C C T A C G A A G G A A C C A A C C T T G C T A G G A A G C A T C C T T G C T A C C T T C C T T G C T T C G T T G C A A G C T T G G T T G C T T G C T A C C T A G G T T C C T A G G T T C C T A G G T A G G T A G C A A C G T +206 A C C A A G G T A C G T T G C T A C C T T C G T A G G T A C G T A C G A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T G C A A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G T A G G A A C C A A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A C C A T G C T A G C T A G C A A G G T T G G T A G G T T G G T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A G G A T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C T A C G T T C C T T C G A A G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T C G A A C C A T C G T A G G A A G G A A G C A T G G A T C G T A C C A T G C A T C G A A G G A T C G T T G C A T C C T T G G T A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G T A G G T A C C A A G C T A C C A T C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T T G G T T C G A T C C T A G C T A G C A T G C T T G C A A C C T A C C A T G G T A G C A T C G T A G G A T G G T A G G A A G C T A C C A T G C A A G G A A G C A T C C A A G C A A C C T A C C T T G G T T C G A A G C T T C G A T C C A T G G A A G C T T G C T A G G T A C C A A C C T A C G A A C G T T C C T A C C T A G G T A C C T A G C T T G C T T G C A A G C T T G C A T C G A A G C T T C C T T G G T A C G A A G G T A G G T A G G T A C C A T G C T A C G A A G C T T G G T A C G T T G C T T C G A T C C T A G G A A C G A A G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A C C A T G G A T G G T A G G A T G C T A C G A T C C T T C G T T C C T T C G T A G G T T G C T T G G T T G G A A C C T A G G T A C C T A G G T A C G T A C C T A G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C A A G G A A C C A T G C A A G G T T G C A T G G T A C G A A G C A T G G T A C C A A G G T A C G A T C C T T C C T A C G T T G C A A C C T T G C A T G G A T G C A A G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C G A A C G A T G G T T G C T A C C A T C C T A G G A A G C A A C C T A G C T A C C T A G C T T G C A T C G T T G C A A G C T T G G T T G C T T G C A A C G T A G C A A G C A A C C A A C C T A G G T A G G T A G C T A G C A +207 A G C T A C G T A C G T T G C T A C C T T G C T A G G A A C G T A C G A A G G T T G C T T G C T T G G T T C G A T G C A A C C T A G C A T C C A A G C T A C C T T G G T T G C A A C C A T G G T T C G T T G C T A G C A T C G T A C C T A C G T T C C A T G C T A C G A T G C A A G C T T C C A A G C T T G G T T G C A T C C T A G C A T C C A T C C T T G C T T G G A T G C T A C G A T C G A T C G T T G G T A G G A A G C A T C G A A G G A T C C A A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T T G G A T G G A A G G T A C C A A C G A T G G A A G G A T G C T T C C T T G C A T C C A T G C T A C C A A C G T T G G T A C C T A C G A A G G T T G G A A G C T A G G A A C G A A C G A T C C A T C G A T G C T T C G A A G G A T G G T T C G T T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G G A A G C T A C C T A G G T A C G T A G C A A C C A T G G T A G G A T G G T A C G T A G C T T G C T A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T A C C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T C C T A C C T A G G A T C C A T C G A T G C T T G G A T G C T T G C T A G C A T G C T T G C A A G G A A G C T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T G G T T C C A T G G A A C C T A G C A A G G T A G C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G A A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C T T G G T T G C A A C C A T G C T T G G T A C G T T G G A T G C A T G C T T G G A A C C T T C G A T C C T A C C A A C C T A C G T A G C A T G G T T G C T A C C A T C C T T G G A A G C A A G C T A G C A A G C T A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A C G A T C G T A G G A A C C A T C C T T G C A T G C A T G C A A G G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C A T G C A A G G A A C G A A C C T T C G T A G C T A C C T A C C T A C G A T C C A T C C A T G C T A G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C A T G C T T C C A A G C T T C G A T C G A A C C A A C G T A C C T A C G T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A C G A A G G A A C C T A G C T A G C A A C G T A C C T +208 A C C T A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T A G G A A G C A A C G A T G G A T G C A A G G T A G C A T C C A A G C A A C C T T G C T A G C T T G C A T C G T T C G A T C C T A C C T T C C A T C C T A C G A T G C A T G C A A C G T T G C A A C C T T C G A A G G T T G C T T G C A T C G T A G C A T G C A T G C T T C C T T G G T A G G A T G G T A G C T T G G T A G C T T G C A A G C A A G G T A G C T A G C T A G G A A C C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A C G A A G G T T G G T T G C A A G C A T G C T A C C A A C G T A G G T A C C A A C G T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A T C C A T C C T T G C A A C G T T C C T A G C A T G G T A G C T T C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T G C T A G C A T C C T T G G A A G G T A C G A T G G A A C C T T G G A A C G T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C A A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A G C T T G G T A G C T T C G A T C C T A C G T A G G T A C G T A G G A T G C T A G C T T C G T T G C T T C C T T C C A A G G T A G G T T G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C T A C C A T G C T T G C T A G G T A C C A A G C T A C G A T G G A A C C T T C C T A G G T A G C T T C C T T G C A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G A T C C T A G C A T G G T T G C T A G G A T C C A A G G A T G C T T C C T T C C T T C C A T G G T T G G A T G G T A C C A A G C T T C C T A C G A T G C A T C G T A G G T A G C A A C G A T C G A T C G T A G C A T C G A A G C T T G C T A G C A A C G T A C C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T G C T T G G T A C G A A C G T T G C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T G C A A G C T A C G A T G C A T C C A T C G A A G C A T C G T T G C A A G G A T G G T T G C T A C G A A G C T A C C A A C C T T G C T A G G A A G C T A C C T T G C T A C C A A C C T T G C T T C G T T G G A A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +209 T G C T A C G T A C G T T G C T A C C T T C G T A G G T A C G T A C C A A G G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G T T G C T T G C A A G C A T C G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A T C C A T C G A A C G A A G G A A C C A A G C T T G G T A G C T T G C A A G C A A G G T T G C A A G C T A G C T A C C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C A T G C A A G C T T G G A A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A T G G T A C G T T G C T T C C T T G G T A G C A A C G T A C G T A G C A T G G T A G G T A G G A A G C A A G C T A G G A A G G T A C C A A G G A T C C A A C C T A C G T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A A G C A T C G A T G G A T G G A T C C T T G C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G C A A C G A T G G T A C C A A C G A A C C A T G C T A C G A A G C A A G G T A G G A T G C A T C G A T C C T A G G A A G G T T G C A T C G A A C C T A G G A T C G T T G C T T C C T T C C A T G G T A C G T A G G T T G C A A G C A A G C T T G G A T G G A T C G T A G G A T C G T T C G A A C C T T C C A T C C T A G C T T G G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T T C G A T C C T T C G T T C C A A G G A A C G A A G C A A C C T T G G A A C C A T G C A T G G T T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T G G T T C C A A G C A T C C T A C C T A G G T T G G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C A T G C A A G G A A G C T T C C A T C G T T C C A A C C T A C C A A G C A T C G A T C G A T G C T T G G A T G C T A C G A A G G A T C G A A C G A T G C T T G C A A C C T T G C T A G G A A C C A T C C T A G G T A C C A T C C T T G C T A C G T T G C A A G C T T G C T T G C T A G C T A C G T A G C T T C G A A G G A A C C T A G G T A G G T A G C A A C G T +210 A C C A A G G T A C G T T G C T A C C T T C G A A G G T A C G T A G G A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T C G T A C C A T G C T A C C A A G G A A G C A T C C T T C G A T G C A A G C T T C G T T G G T T G C T T C C A T C C T A G C A T G C A T G C T T C C T T G G T A G C T A C C A T C G T T C G T A G G A A G C A T G C A A G G T A G C A A G C T A G C A A C C A T G C A A G C T A G C A A G G T T G G T A G G T T G G A T G G T A C C A T G C T T G G A A C G A A G G T A C C A T C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C C T T C G A A G C T A G C A A G C T A G G A A C G T A C G A T G C T A C C T A C C T T C C A A G G A T C C A T C G T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G G T A G C A T C C A A G G T A C G A T G G A A G G T A G G A A G G T T C G A A G G A A G G T A C C A T C G T T C G A T G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A T C C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T T G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C G A T G C T T G C A T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G T T G C A T G C T A C C T A G G T T C G T T C G T A C C T A G C T T G C T A G C T A C C A A G G A A G C T T C C T T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A A C C T A C G A A G C T T C C A A C G A T G C T T G G T A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A G C A T C C T A G C T A G G A A G C T A G C T +211 A C C T A G G A T C C T A G C T A C C T T C G A A G G T A C G A A C G A A G G T T G C T T G C T T G G T T G G A T G C A T G G T A G C A T C C A A G C T A C C T T G C T A G C A T C G A T G G T A C G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A A C G A A G C T A C G A A G C T T C G T T G C A A G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C C A T C C A A G G A A C G A A C G T T G C A T C G T A G G T T G G A A G C T A G G A A C G T A C G A T G C A A C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C T A G G A T G C T A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A C G T A G C A T G G A T G C T T G G A T G C T A C G T A G G T A C G T T G G A T G C T A G C T T C G A T C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T G G T T C C A T G G A A C C T A G C A A G G T A G C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G A A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C T T G G T T G C A A C C A T G C T T G G T A C G T T G G A T G C A T G C T T G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A C C T A C G T A C C A T C C T T C G A A G C A A G G T A G C T A G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G A A G G A A C G A A C C T T C G T A G G A A C G T T C C T T C C A A G C A T C C T A G C T T G C T T C G T T C C A A G C A A G G T A C C A A G C T T C C T A G G T T G C A T G C T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +212 A C C T A C G T A C C T T G C T A G C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T A C C T T C G T A G G T T G G T T C C T T G C T A G C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A A C C T T C C A T G G T A G C T T G C A T C G T T G G T A G C T T G C T A G C A A G G A T G C A A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T C C A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T A C C T A C G A A C C T A G G A A C G T T G G A A C G A A C G A T C C A T C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A G G A T G G T A C G T A G C T T G C T A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C A A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A C C A T C G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G A A G C T T G C T A G C T T C C T T C C A A G G T A G G T T G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C T A C C A T G C T T G C T A G G T A C C A A G C T A C G A T G G A A C C T T C C T A G G T A G C T T C C T T G C A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G A T C C T A G C A T G G T T G C T A G G A T C C A A G G A T G C T T C C T T C C T T C C A T G G T T G G A T G G T A C C A A G C T T C C T A C G A T G C A T C G T A G G T A G C A A C G A T C G A T C G T A G C A T C G A A G C T T G C T A G C A A C G T A C C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T T C G T A C G A T C C T T C C T A G G T T G C T A G C T A G C A T G G A T G C A A G C T A C C T A G C T A G G T T C G T A C G T A G C T A G G T A G C T A G G A A G G A A G C T T C C A T C G T A G C A A C C T A C C T A C C A T C G A A G G A A G C T A G G T A C C A A G G T T C G T T C G A A C G A A C C A T G C T A C C T T G C T A G G A A C C A T C C T T G C T A C G A A G C T T G G T T C C T T C C T A G G T T G G T T C C A A G C A A C C T T G C T A G G A A G C A A C G T T G C A A G C A A C C T A G C A +213 A G C T T G G A T G C T T C C T A C C T T C G A A G G T A G G T A G G A A G G T T G C T T G C T A G G T T C G A A C C T A G G T A C C A T G C A T G C T A G C A T G G T A G C A T C C T T C G A A G G A T G G T A C C A T C C T A G C T A G G A A G C T T G G A T C G A T G C A A G C T T C G T T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C G T T C C T A G C T A G C T A G G T T G G T A G G T T C C T A G G T A G G T T G C T A C C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A G G A T C G A A G G A A C G A A G G T A G G A A C G T T G G T A G G T A C G A T C C T T C G T A G C T T C G A A G G A A C G A A G G T T C G T T C G T T G C T T G C A T G G T T C C A T G G A A G C A A C G A A G G A T G G T T C G T A G G A A C C T A C C T A G C T A C C A A G C T A G G A T G G T A C C A T G G T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G T A C G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A C C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C C T T C G T T G C A A C C A T G G A A C C A T G C A A G C T T G C A T C C A A C C T A G C T T G C A T G G T T C G A A G G A T C G T A C C A T C G A A G C A T G G A A G G T A C C A A C G T A C G A A C G T T C C T A C G T A G G T A C C A T C C A A C C A T C G T A G G T A G C A T C G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G T A G G T T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A G C T A C G T A C G A T G G A T C C T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A G G A T G C T A C C T T G G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T T G G T A C C A T G C A T G C A A G G A T G G A A G G A A G C T A C C T T G G T A G C A A C C A T C C T T C C T A G C T T C C T A G C A A G C T T C G T T C C A A G C T A C G T A G C T A C G A A C C T T G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A C G A T C G A T C G A A G C A T C G A T C G T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G C A A C G A T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T C C T A G G A A C C T A G G T A G G T A G C T A G C A +214 A G G T A C G T A C G T A G C T A C C T T G G A A G G T T G G T A C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G A A C G A T G C T A G C A T C G T A C C T A G G A A C C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T A G C T T G C A A C C T T G G T T C C A T C G T T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T G G A A G C T T G G T T G C T A G C A A G G A A G G T A G G A A G G T A C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G C T T C C T T C G T T G G T A C C A A G G A T G C A A G C T A C C A A G G A A C C A A G G T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T C G A T G C T T C G A T C C T A C C T A G G T A C C T T C C A A G C T A C C A T G C T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A G C T A C G A A C C A T G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A G G T T G C A A C C A A G G T A G C A T G G A A C G T A G G A T C G T A G G A T C C T T C G T T G C T T C G A A C G A T G G T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T G C A A G C A A C C A A C C T T G C T T G C T T G G A T G C T T C C A T C C T T C G T A G G A A G C T A G C A A G C T T G G T A G C A A C C A T G C A A G G T T G G A T G G A T G C A A C G A A C G T T G G A A G G A T G G A T C C T T C C A A G C A T G C T A C C T A G C T T G C T T G G A A G C T T C C T A G C T A G G T T C C T T G G T A C G A T G C A A G C T T G G A A G G T A C C T T C C T T C G T T G C A A C G T A C C A A G C A T G G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T A C C T A G C T A C C A T C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G C A A C G T A C C T A G C T A G C A A C G T A C C T +215 A G G T T G G A T G C T T G C T A C C T A G C T A C G T T G C T T G C A T C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T A C G A T C G T A G C A T C C T A C C T A C G T A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C A A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A C G A A G C T T C G T T G C A A G C A T G C T A C C A A C G T A G G T A C C T A C G A A G G T T G G A A G C T A G G A A C G T A C G A T G C A T C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A G G A T G G T A C G T A G C T T G C T A G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T A G C T A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T T G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C A A C G A A G C T A C C A T G C A T C G A T G C A T C C A A C C A A C C T A G C T A G G T T C G A T G C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C A T C G A T C C T A G G A T G C T T G C T T C C T T C G T A G G A T C C T A G G T T G C A A C C A A G C T T G G A T C G T T C G T A G G A T C G T T C G A A C C T T C C T A G C T T C G T A G G T T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C T T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A C C A T C C T A C G T A C G T A G C T T C C A A G G T T G G A T G C A T G C T A C C T A G C T A G G T T C G T A G C A A G G T A G C A A G C A T G C A A G G A T G C T T C C A T C G T T G C A A C C A T C C T A G C A T G C A T C C A T G C A A G G A T G C A A G C A T G G A T C G A A C G A T G C T T G C T A C G A T G C A T G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A G G T A G C A A C G T +216 A G G A A C G T A C C T A G G A T G G A T G C T T G G T T C C A A C C A A G G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A T C C A A G C A A C C T T G C T A G C A A G C A T G G T T C G T T G C T A C C A A C G T T C G T A G G A T G C A T G C T A C G T T G C A A G C T T C C A A G C T T G G T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G G A T G G T A G C T T G G T A G C T T G C A A G C A A G G T A G C T A G C T A G G A A C C T T C C T T G C T T G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C A A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C T A G G T A C C A A G C A A G G A A G G A A C G A T C C T T C C T T G G A A C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C G T A G C A A G G A A G C A T G C T T G C A T C C T T C C T A G G T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G C A T C C T A C G T T C C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A A G C A T C G A A C C T T C G T A G C T A G C T T G G A T G C T A C C T T G G T T G C T A G G T T G C T A G G T A C G T T C C A A G C T A C C A T G C T A C C A A G C A T G G T T G C A A C C A A C G T T G C A T G G T T G G T A G C A T C C T T C G T A G G A A G G A A C C A T G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G A A G G A T G C A A G C T T G G T A G G A T G G T T C C T T C C A A G C A T C C T A C C T A G G T T G G T T C C A A G C T T C C T T G G T T C G T T C G T T C C T A G C T T C G A A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C T A G C A T C G A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G G T T C C T T G C A A G C A A C G T A G G T A C C A A C C A A C C T A G G T A G G T A G C A A C G T +217 A G G T T G G A T G C T T C C T A C C T T C G A A G G T A G G T A G G A A G G T T G C T T G C T A G G T T C G A A C C T A G G T A C C A T G C T T G C T A G C T T G G T T C C T T C C T T C G A A G G A T G G T A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C T A G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A G G A A C G A T G C T A C C T A C G T A C C A A C G T A G G T A G G T A C C A T C C T A C G T A C G A A G C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T C G T A C G T A G G A A G C A A G G T T C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A G C T A C G A A C C A T G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C C T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A G G A T G C T A C C T T G G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T A G G A A C C A T G C A T G C A T G G A T G G A A G G A A G C T A C C T T G G T A G C A A C C A T C C T T C C T A G C A T C C T A C C T A G C T T C C T T G G A A G C T A C C T A G C T A G G T T C G T A C G T A G C T A G G T A G C T A G C A A G G T A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G A T G C T T G C T A C G A T G C T T G G A A C G A A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C G T A G C A T G C A A G G A T C C T A G C T A G G A A G C T A G C T +218 T G G T T G G A T G C T A G C T A C C T T G C T A G G T A G G T A C C T A G G T T G C T T G C T T G G T T C G A T G C A T G G T A G C A T G C A T C C T T G C A T G G T A G C A T G C A T G G T T G G T T G C T T C C T T C C A A C C T A C G A A G C A T G C A A C G T T G C A A C C T T C C A A G G T T G C T T C C A T C C T A G C A T C C A T C G T T C C T T G C A A G G A A C G A A G C T T C G T A C C A A G C A T G G A A G G T A G C T A C C T A G C A A C G T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C C A A G G A T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G T A C G T T G G A A C G T T C G T A G G A A G C T T G C A T G C T A G C T T C G T T C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C A T C G A A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T C C A T C C A A G C A A C C T A G C T T G G T T C G A T G C A T C C T T C C A A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A T C G T T C C T T C C A A G C A T G C T A G C T A G C A T G G A T G C A A G C T T C C T A G C T A G G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A C G A T G G A T C G A A G C A T C G A T C G T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G C A A C C A T C C T A G C T A C C A T C C T T G C T A C C T T G C A A G C T T G G T T G C T A G G A A C G T A G C T T G C A A G C A T C G A A G C T A C C A A G G T A C C T +219 A G G T T G G A T G C T T G C T A C C T A G C T A G G T A G G A T G C A A G G T A G C T T G C T A C G T T C G A A G C T T G G T T C C A T G G T T G G T T G C A T G C T A G C A T C C A T C G A A C G T T G G T A C C A T C G T A C C T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G G T T G C T A G C A T C G T A G C A A G G A T C C T T C C A T G G T A G C T T G C A A G C T T C G T T G G A A G C A A G C A A G G T T G C T A G C T T C G A A G C T A C C A A G C A A C G T A G G A T C C T A G G T A G G T A G G T A G C T T C C T T G C A A C G A A G G T T G C T A C G A T G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A G G A T G G T A C G T T C G T T G C T A G C A A G C T A G G A A C G A A C G A T G C T A G C A A C C T T C G T T C G A A G C A A G G T T G G T A C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A A G C A T C G A A C C T A C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G A T G C A A C C T A G G T T G C T T C C A T G G T T C C A T G G A T C G T A C G A T C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T T G C A A C C T A C G A A G C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T A G C T A G C A A C G T A G C A A G G T A G C T T G C A T G C A T C C T T G G A A G G T A G C A T G G A A C C A T G C A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C G T T G C A A C C T A C G T A G C A A G C T T G G A A G G T A C C T T G C T A C G A A C G T T C C T A C C T T G G T A C G T T G C T T C C A T G C A A G G T A G C A A G G A A G C T A C C T T G C A A C G A A G C A T C C A A C G A A C C A T G C T A C G A A G C A A C G T A C G A T G C T T C G A T C C T A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G G T T C G T A C G A T G G A T C G T A G G T A G C A A G G A T C C T T C G T A G C T A C G T A C G A T G C T T G G A T G G A T G C A T G G T A G C T T G G T A C G T T G G A T G C A A G C A T G G A A C C A A G C A T C C T A C C A A C C T A G G T A G C A A G G T T G C T T C C A T C G T T G G A A G G A A G G T A C C T T C C T T G C A T G C A A C C A T G C A T C C T T C C A T G G T A G G A T G C A A G G T T C G T T C G T A C C T T C C T T G C A A G G T A G C T A G C A A G C A T G C T T G G A A G C T A C C T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G T A G C T A C C T T C G T A G C A T C C A A C C T A C C A T G C A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C G T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +220 A G G T T G G A T G C T T G C T A C C T A G C T A G G T A G G A T G C A A G G T A G C T T G C T A C G T T C G A A G C T T G G T T C C A T G G T T G G T T G C A T G C T A G C A T C C A T C G A A C G T T G C A A G C A T G G T A G C T A G G A T G C A T G C A A C C T T G C A A G C A T C C T A G G T T C G A T G C A T C C T A G C A T C C A T G C A T C G A A G G A A G C T A G C A A G C T T C G T A G C A A G C A A C C A T G G A T G C A A G C T A G C T A C C T T C C A A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G G T A G C T T C C A A G G T A G G T A C C A A C G A T G C T A G G A T G C T T C G T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C C T A C G T A C C A A G C A A G G T A G C T A C C T T C C A A C G T A C G T T C G T T C G A A G C A A G G T T G G T A C G A A G C T T G C A T G G T T G C T T C G T T C C A A C G T A G C A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T A C C A T G C A A C G T T G C A T G C A A G G T A G C T T G C A A G G T A C G A T G G A A G C T A G C T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T T C C A A G C T T C G T T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A G G T A G G T A C G T A G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A C C A T G G T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T A C G A T G G T A C C T A C C A A G G T A G C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C A T G G T A C G A A G C T A G G T A C G T A G C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C A T G G T A C G T A G G T A G C A A G C T A C C T A C C A T C G T T C G T A G G A T C G T T C G A A C C T T C G T A G C T A G G A A G G A T G C T A C C T T G G T A C C A T G G T A G C T A G G T A C G T T G G A T G C A T G C A T G C T A C C A T G G A T C C T T G C A A C C T T G C T T G C A A G G T A C G T T C C A T C C T A G C A A G C T T G C T A G C T A G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C A A C G T T G G T A G C A T G G T T C C T T G C A A C G T A C C T A G C A T G G T T G G A T C C A A G C A A C G T T G C T T C G A A C C T T G G T T G C T A G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C G A A G G A T C C A A G G T T G C A T C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C C A T C C T T C C A T G G T T G C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A G G T A G C A A C G T +221 A C C T A G G T A C G T T G C T A C C T T G C T A G C T A G C T A C G T A G G T T G C T T G C T T G G A T C G A T C C T A C C T A C C T T C G T T G G T A G C T T G C T A G C A T C G A T G G T A C G T T G G T A G C A T C G T A G G T A G G T A C C A T C G A A C C T T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A C C A A C G T T G C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A A C C A T C C A A G G A A C G A A C G T T G C A T C G T A G G T A G G A A G C T A G G A A C G T A C G A T G C T A G C T A C C T T C G T A C G T T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A C G A A G C T A G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T T G C T A G G T A C G T A G C A A G G A A G C A T G C T T G C A T C C T T C C T T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T C C T T C C A A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G A T C C T A G G A T C C T A G C T T C C T T C G T A G G A T C C T A G G T T G C A A C C A A G C T T G G A T C G A T C G T A G G A T C G T T C G A A C C T T C G T A C C T T G G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C A A G C T A C C A T G C T A C C T A G C A T G G T T G C A A C C A A C G T T G C A T G G T T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G A A G G A T C C T A G G A A C C T A G C A A C C A T C C T T G C A T G C A T G C A A G C A A G G T T G G A T C C A A G C T T C C T T G C T A G G T T C G T T G C A A G G T A G C A A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C A T C C T A C C A T G C A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T A C G T T G G A A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +222 A G C T A G G T T C C T T G C T A C C T T G C T A G C T A G C T A C G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A C C A T G C A T C G T A C C T T G C T A G C A A G C T T G G T A C C T T G G T T C C T T G C T A G C A A G G A A G C T T G G A A C G T T G C A A G C T T C G A T G G T A G G T T C G A T C C T A G C A A G G A A C C T T C C A A C G A A G C T A G C A T C G T T G G T A G C T A G C T A G C A A G G A T G C A A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T C C A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G T A C C A A C G T T G G T A C G T A C G A T C C A T C G T A G C A A G C T A C G T A G G A T C C T T G C T A C C T T C C A T C G T T C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G A A G G T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A G G A A G G A T G G A T G C T A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A C G T A G C A T G G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T T C C A A G G A A C G A A G C T A C C A T G C A T C G A T G C A T C C A A C C A A C C T A G C T A G G T T C G A T G C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C A T C G T A G C A A G G A T G C T T G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G T T C G T A G C A A G C A T C G A A C C T T C G T A G C T A G C T T G G A T G C T A C C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G G T A G C A T C C T T C G T A G G A A G G A A C C A T G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G A A G G A T G C A A G C T T G G T A G G A T G C T T C C T T C G T A C G T A C C T T C G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A T C G A A C C T T C G A A G C T A C C T A C C T A G C A T C C A T C G A T G C T A G G A T G C A A C C A T G G T T G C T A C G A A G C T A C C A A C C A T G C T T C C A A G C T T C G A T C G A A C C A A C C T A G C T T C C T T C C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A G G T A G C A A C G T +223 T G C T A G G A T C C T T G C T A G C T T C G A A G G T A C G A A C G A A G G T T G C T T G C T T G G T T C G A A C C T T G G T A C C A T C C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T G C A A C C T A G C A T G C A T C C T A C G A A G C T A G C T T C G T A G C T T G G T T C G A T C C T A G C A A G G A T C C T T C C A A C G A A G C T A G C T A G C T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A C C T T C C T A G C T A G G T A G C T T C G T A C G T T G G A A G G T A C C A T G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C T A G G A A C G T T G G A A C G A A C G A T G C T A G C T A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A A C C A A C G T T G C A T G C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C A A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G G A T C C A T C C T A C G A A G C A A G G T T C C T A G C A T C G T T C C A A G G A A G G T A G C T T G G A T G G A T C G A T C C T A C G T A G C T A C C T A G G A A G C T A G C T T G C T T C C A T C C T A C G T T C G A A G C A T G G A A C C T A C G A T C G A T C G A T G C T T C C T T G C T A G C A A C C T T C G A A G C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C A T C G T A G C A A G G A T G C T T G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G T T C G T A G C A A G C A T C G A A C C T T C G T A G C T A G C T T G G A T G C T A C C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A T C C T T C G T A G G A A G G A A C C A T G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G A A G G A T G C A A G C T T G G T A G G A T G G T T C C T T C G T A C G T A C C T T G C A A G G T T G G A T C C A A G C T T C C T T G C T A G G T T C G T T C C T A G C T A G G T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +224 A C C T A G G A T G C T T C G A T G G A T G C T A G G T T G G T A C C A A G G A T C C T T G C A A C G T T G G A T C C A T G G T A G C A T C C A A C C A A C C T T G C T A G C A T C C A T G G A T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C T T G G T T G G T T C C A T C C T A G C A T C C A T C C T T G C T T G G T A G G A A C C A T G G T T C G T A C C T A G C A A G C A A G G A T G C A A G C T A G C A A C G T A C C T A G C T A C C T A G G T T G G T A C C T T C C T A G G T A G G T A G C T T G G A A C C A A G C T T C C A A C G A A G G T A G G T T G C T A C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C C T T C C A A C G T A G G T T C G A A C G A A C C T T C G T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T G C A A G G A T C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G T A G C T A C G A T G C T T G G A T G C T A C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G A T C C T A G G A T C C T A G C T T C C T T C G T A G G A T C C T A G G T T G C A A C C A A G C T T G G A T C G A T C G T A G G A T C G T T C G A A C C T T C G T A C C T T G G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C A A G C T A C C A T G C T A C C T A G C A T G G T T G C A A C C A A C G T T G C A T G G T T G G T A G C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C C T T C C T T C C A A G C A T C C T A C C T A G C A T G G A T G C A A G C T A C C T A G C T A G G T T C G T A G G A A G G T A G C A A G C A T G C A A G G A T G C T T C C A T C G T T G C A A C C A T C C T A G C A T G C A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A G G T A G C A A C G T +225 A G G T T G G A T G C T A G C T A C C T T G C T A G G T A G C T A C C T A G G T T G C T T G C T T G G T T C G A T G C A T G G T A G C A T C C A A C C T T G C T T G G T T C C T T G C A T G G T T C C T A G C T A C C A T C G T A C C A A C C A A G C A T G C A A C G T T G C A A C C T T C G A A G G T T G C T T C C A T C C T A G C A T C C A T C G T T C C T T G C A T G C T A C G A A G C T T C G T A C G A T G C A A G C A A G G T T G C T A C C T A G C A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T A C G T A C C T A G C A T C G A A C G A A G G T A G G A A G C T T G G T T G C A A C C A T C C A A C C A A G G A A C G A A G G A A C G A A G G T A C C A A G C A T C G A A G G T A C G T T G C A T C G T A G C T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T T G C A T G G A A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T T G G T A G C A A C C A A G G T A C G A T G G A A G G T A G G A A G C A A G G A T G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C A T C G A A C C T A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A A C G A T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G G T T C C T T G G A A C C A A G C A A G G T T G G A T G G T A G G A T C C T A C C T T G G T A G G A A C G T T C C T T C G T A C G T A G C T A G C T A G C A T G G A T G C A A G C T A C C T A G C T A G G T T C G T A G C T A G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A G C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C T T G C T T G G A A C C A A C C T A G C T A C C T A G C T T G C A T C G T T G C A A G C T T G G T T G C T T G C A A C G T A G G T T G C A A C C T T C C T A G G T A G G T A G C A A C G T +226 T G G T T G G A T C C T A G C T A C C T T C G A A G G T A G G T A C C A A G G T T G C T T G C T T G G T T C G A T C C A T G G T A G C A T G C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T T C C T T G C A A C G T A G G A A C C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T G G A T C C A T C C T T C G T A G G A A C G A A G C T T C G T A G C T A G C A T G G A A G G T A G C T A C C T A G C A A C G T T C C A A G C T A G C A A G G T T C G T A G C T A G G A A G G T A C G T A G C T T G G A A C G A T G G A T C C A T G G A T G C T A G G A T G C A A C G T T G C A A G C A T G C T A C C A A G G A A C G A T G C T A C C T A C G T A C C A A C G T A G G T A G G T A C C A T C C T A C G T A C G A A G C T A C G T T G G A A C C T T G G A T C G A A G C T T G C A T G C T A G C T T C G T T C C A T G G A A C C A A G G A A G G A T G G A A C C A T C G T A G G A A G G A A G C A T G G A T C G T A G C A T G C A T C G T T G C A T C G A A G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G A A G C A A G G T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A T C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T T G G T T G C T T G C A A G C A T G C A T C C A A G C T T C C A T C G T T G C A A C C A T C G T A C G A T C G A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C A T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +227 T G C T A G G A T G C T T C G A T G G A T G C T A G G T T G G T A C C A A G G A T C C T T G C T A C G T T C G A A C C T T G G T A C C A T C C T T C C A A C C T T G C T A G C A T G C A T G G A T C G T T G C A A G C A T C G T A G C T A G G A T G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A A G G A A C C T T C C A T G G T A G C T A C G A A G C T T C G T A G C A A G C A A G C A A G G T T G C A A C C T A G C T A C C T T C C A A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G G T A G C T T G C A A C G A A G G T T G C T A C G A T G G T T G G A T G C T T C C T T G C A A C C A T G C A A C C A A C G T T G G T A C G A T C G A A C C T A G G A A G C A T G C T A C G T T G G A T C C T T C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T G C T A G G T A G C A A C C A T C G T A C C T T G G A A G C T A G G T T G C A A C G T A G G A A G G T A C C A T C G T A C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G G A T G G A T G C A A C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A G G A A G G T A G C A T C G A T G C T T G G A T C C T A G C T A G C T T G C T A G G A A G G A A G C T T G C A T G C A T C C T T G G T T C G A A C G A A G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T G G T A G G T A G C T T C C T A C C A T G C T A C C T A G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A C C A A G C A A G C T A G G T T C C T A G C T A C C A T G G A T C G A A C C T T C G A A G G T T G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T T G G T A G C A A G G T T C G T A C C A T G G A T C G T A G G A T C G T T C G A A C C T T C G T A G C T T C G A A C G A T G C A T G G A T G G A T G C A T G G T A G C T T G G T A C G T T G G A T G C A A G C A T G C T T C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G T T G C T A G C A T C G T T C G T T G G A A G C T A G C T A G C T A C C T A G G A A C C A T G C A A G G T T G C A T G G T A G G A A G G A A G C T T C G T A G G A A C G A T C C T T C C T A C G T T G C A A C C T A G C A T C C T T G G T A G C T A C G T A G C T T C G T T C G T T C C T T G C T A C G T A G C T A G C A A G C T A G C T T C C A T C G A A G C A A G C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +228 A G G T A C C T A C G A T G C T A C G T A C G T A G C A A C G T T C C A A C G T T C C T T G C A A C G T T C G A A C C T T G G T A C C A T C C T T C C A A C C T T G C T A G C A T C C A T G G T T G G T T G G A A G C A T G G T A C G T A G G A T G G A T C C T T C G T T G C A A C C T T C G A T G C T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G C T T C G T A G C A A G C A A C C A A G G A T G C A A G C T A G C A A C G T A C C T T G C T A G C A A G G T T C C T A G C T T C C A T G C T T C C T T C C A T G G A A C G A A G G T A C C A A C G A A G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A G G A T C G A A G C A T C G T T G C T A G C A A G C T T G G A A C G A A C G A T C C A A C C T A C C T T G G T T C G A A G G T T C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G C T A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G T T C C A T G G A A G G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G T T C G T T G C A T C C T A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G T A G C T A C G T T G C T T G G A T C C T T C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C C A A G G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G G T A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C G A A C G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T A G C A T C C A T G G T A C G T T G G T T G C A A G C T A C C A A G C A T G G A T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T A G G A T G C T T G C T T G G T A C C T A G G T T G C T A G G T A C G T T G G A T G C T A G C A T G G A T C C A A G C A T C G A A C G A T C C T T G G T A G C T T C G T A C C T T G G A A C C T A G C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G A A G G A T C C T A G G A A C C T A G C A A C C A T C C T T G C A T G C A T G C A A G G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C A T G C A A G G A A C G A A C C T T C G A T G C T A C C T A C C T A G C A T C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +229 A G G T A C C T A C C T T G C A T G C T T G C T A G G T A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C A T C C T T C C A A C C T T G C T A G C A T C C A T G G A T C G T T G C A A G C A T C G T A G C T A G G A T G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T T G G A A G G A A C C T T C C A T G G A A G G A A C G A A G G T T C G T A G C T T G C T A C C A A G G T A G C T A G C T A G C A A C G T T C C T A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G C T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C G T A G G A A C G T T G G A A C G A A C G A T C C A A C G T A G C T A C C A A G G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T C C T A G G T A G C A A C C A A G G T A C G A T G G A A G G T A G G A A G C A A G G T A G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G T A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T A G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G A A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A T G C A T G G A T G G A T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G A A G G A T G C T T G G A T G G A T C G A T G G A T C C T T C C T A C G T T G C T A G C A A G G T T G G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C T A G G A A C C T A G G T T G C A A C C A A C G T +230 A G G A A C G T A C G A T G C T A C G T A C G T A G C A A C G T T C C A A C G T T C C T T G C T A C G T T C G A A C C T T G G T A C C T A C C T T G G T A G C T T G G T A C C T T C C A T C G A A G C T T G C T T C C T T C C T A G G T A G G A T G C A T G G A A C G T T G C A A G C A T C C T T G G T T G C A T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C T T G C A A G C T T C G T A G C A A G C A A G C T A G G A T G C A A G C T A G C T A C C T T C C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A T C C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C C T A C G A T G C A A G C T T G G A A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G G T A C G T T G C T T C C T T G G T A G C T T G G A A G G T A C C T T G G T A C C T A G C T T G G T T C G T A G G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T G G A A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C G T A G C A A G C T A G C A T G C T A C C T T C G T T C C T T G C A A G C A T G G T A C C A T G G A A G G T T G C A T G C T T C C A A G C T T G C T T G C T T C G A A G C A A C C T T C C T T C G A T G G T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C C A T C C T T C G A A G C A A G C T A G C T A G C T T C C T T G C T A C C A T G C A A G G T T G G T T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G T T G C A T G C T A C G T A G C T A C G A A C C T A G G T T G C T T C G T A G C T A C G A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A G C A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G A T G C T T G C A A C C A T G C T T G G A A C C A A C C T A G C T T C G A A G C A T C C A T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T G C A A G C A A C C T A G C T A G G A A G C T A G C T +231 A G G A T G G A T G C T T G C T A C C T A G C T A C G T T G C T T G C A T C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T A C G T T C G T A C C A A C G T T C G T A G G A A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G G T T G C T A C G A A G G T T G G A T G C A A C G T T G G A A C C T T G G T T C C A A C G T A C G A T G C T A C G T A C C A T G C A A G C T T G G A A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G A A C G T T G C T T C C T T G G T A G C A A C C A A G G T A C G A T G G A A G G T A G G A A G C A A G G T A G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C T T C C A A C G A A G C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T C C T T C C A A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C G T T C C T T C C A A G C A T C C T A G C T A G C A T G G A T G C A A G C T A C G T A G C T A G G T T C G T A C G T A G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A G C A A C G A A G C T A C C A A G G T A C C T +232 A C C A A G G T A C G T T G C T A C C T T G G T A G G T A C G T A C G A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T G C A A C C A T C C T A C C A A G G A A G C A T C C T T C G A T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G G T A G G A A C C A A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A C C A T G C T A G C T A G C A A G G T T G G T A G G T T G G A T G G T A C C A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C T A G C A A G C A T G G T A G G T A C G A T C C A T C G T A G C T T C G T T C G A A G G A A G G T T G G A T C G A A C C T A G C A T G G T A G C T T C G T A C C A A G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C T A G G A T G C A A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A C G T A G C A T G G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T A G G T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G A T G C T T G C A A C C A T G C T T G G A A C C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G G T T G C T A G G A A C G T A G C A T G C A A G C A T C C T A G C T A G G A A G C T A G C T +233 A G C T T G G A T G C T T C C T A C C T T C G A A G G T A C G T A C G A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A G C A T C G A T G C A A C C T T G C T A G C A A G C A T G G A T C C T T G C A A C G A T C C T T G C T A G G A A G C A T C C T T C G A T G C A A G C T T C C T T G G T T G G T T C C A T C C A A G C A A G G A A C C T T C C T T G C A A G G A A C G A A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A C C T T G C T A G C T A G C A A G G T T G G T A G G T T G G A T G G T A C C A T G C T T G G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C T A G G T A C G A T G C T T C G A A C G T A C C A A G C A T G G T A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C G A A G G T A C G A T G G A A G C T A G G A A G C A A G G T A G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C T A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C A T G C T T G G A A C C A T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +234 A C C A A G G T A C G T T G C T A C C T T C G T A G G T T G G T A C G A A G G T T G G T T G C T T G G T T C G A T C C T T G G T A C C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G G T T G C T A C C A T C C T A C C A A G G A A C C A T G G T A C G T T G G A A C C A A C C T A G C T T C C T T C C A T C C T A G C A A G G A T C C A T C G A A G G T A G C T T G C A A G C T T C G T T G G A A G C A A G C A T G G T T G C T A G C T A G G A A C C A T G C A A G C T A G G T A G G T T G G T T G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C C T A C G A A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G C T A C C T A G C A T G G T T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T A G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G C A T C C T A C G T T C C A A G C T T C G A A G G A T C G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C A A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A G G A T C C T T C C A A G C T T C C T A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T C G A T G C A A G C T T G G A A G G A A C C T T C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A C G T A C C T A G C T A G C A A C G T A C C T +235 A G G A T G G A T G C T T G C T A C C T A G C T A C G T T G C T T G C A T C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T A C G T T C G T A C C A A C G T T C G T A G G A A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G G A A C G A A C C T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C C A A G G A A C C A A G G T T C C A A C C A T G G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G C T T C C T A C G T T C C A A G C T T C G T T C G A A G C T A C G T T G C T T C G A T C C T T C G A A C G A T C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T C C T T G G T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A C G T T C C T T C C T A G C A T C C T A G C T A G G T T C G T T G G A T G C T A C G T T G C T A C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A G C T A C C T T C G T T G C A A G C T A C G A A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T A G G A A G G T A C C T A G C T A C C A T C G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +236 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C A A G G T A C C A A G C A A G G A A G G A A C G A T C C T T C C T T G G T A C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T A G C T A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T A G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G C A T C C T A C G T A C C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T G C T A G C T T C G T A G C A A G G A T C C T T C C A A G C T T C C T A G C A T G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T G C A T G C A A G C T T G G A A G G A A C C T A C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C A A C G T A C C T A G C T A G C A A C G T A C C T +237 A G G A A C G T A C G T A G C T A C C T T C G A A G G A A C C A A C G A A G G T T G C T T G C T A G G T T C G A T C C T T G G T A G C A T C G A T G C T T G C T T G G T T G C A T C G A T G G T A C G T T G C T A G C A T C G T A C C T A G G A T G C A T G C A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G G A A C G A A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C C T A G C A A G C T A G C T A G G A A C C T A G C A A G G A A G G T A C C T A G C A A G C A A C C T A G C A T C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A C G T T G G T A G G A A C G A A C C T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A G G T A C G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G C A A G C A A C C A A C G A A G C A A G G T T C C A A C C A T C G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T T G C T A C C T A G C T A G G T T C G T A C C T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T T C C T A G G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +238 A G C T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T C C T T G C T T G G A A G G A A G C T T G G T A G C A T G C T T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C G A T G G T A G G T T G C A T C C T A C C T T C C A T C C T T C C A T C G A A G C T A C C T A G G T T G G T A G C T T G C T A C G A A G G T T G C T A G C T A G C T A G C T T G C T A G C T A G C T A G C T T G C T A C C T A G G A T G C T A C C T A G C T T G G A A C G A A G C T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T C C T A C G A A C G T A G G T A G C A A C C T A C C A T G C A A G C A A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C G A A G G A A C C A A G G T T C C A A C C A T G G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T T C G T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T A C G A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G G T A G G T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A A G C T A C G A A G C T T G C T T G C T T G G T T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A A C G A A G C T A G C T A C C T T G C A T G C A A C C A T G C A A G G T A G C A T G G T A G G A A C G A T C G A T C G T A C G A A C G T T C C T T G C A A C G T T G C T A G C T A G C T T G G T T G C A A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C G A A G G A T C C A A G G T T G C A T C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C C A T C C T T G C A T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +239 A C G T A C C T A C G A T G C T A C G T T G C T T G G T A G C A T C C A A G G T T G C T T G C T A C G A T C G A T C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T C G A A G G A T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C T A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C C T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G T A G C A A C C A A G G T T C G T A G C A T C G T T C C T A C G T A G G A A C C T T G G T A C C A T G G A T C C T A C C T A G G T A C G T A G C A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C T A G C A T C G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T A C C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +240 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G C T A C C T A C G T A G G A A G C A A C G A A C G A A C C T T G G T A C C T A C C T T C C T T G C T T G G T A C C T T C C A T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G C T T C C A T C G A A C C T A G G T A G C T A G C A A G C T T G C T A C C T A C C A A C G T T G C A A G C A A C G T A G C T T C C T A G G T A G G T T G G T T C C T T G C A T G G A A C G A A G C T T C C A A C G A A G G T A G G A T G C T T G C T T G C A A C C A T G C A A G G A A C G A A C G T T G C A T C G T A G G T A G C A A C G T T C C T T C G T T G G A T G C T T C G T T C C T T C G A A G G A A G G A A C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G A A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G G T A C G T A G C T T C C T T G G T A G C A A C C A A G G T A C C T T G G A A C C T A G G T A G G T T C G T T G C T A G G T A C C A T C G T T C G A T G G T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T G G T T C C T T G G T A C C A A G C A T G G A T G C A A C C A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T T C G T A G C A A C C T A G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G G A T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A T C G A A C G T A C G A A G C A T G G A A G G T A C C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A A G G T A C C A T G G T A C C T A G G T A C G T T G G A T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A G G A A G G A A G C A A G C T T G G T A G G A A C C A T G C A A G C T A G G T T G G T A G G A A G G A T C G T T C G T A G G A T G G T T C C T T G C A A C G T A G C T A G C A T G G T T G G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T A G G T A G C T A C C A A G G A T G G A A C C A T C G T T G C A A C C A A C C T A G G A T G C A T C G A A G C A A G G T A C C A T G C A T G C T T C C T A C C T T G C T T G C T A G C T T C C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C T A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +241 A G C A A C G T A C C T T C C T A C C T T C G A A G G A A C G A A C C A A G G T T G C T T G C T T G G T T G G A A G C A A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C T T G G T T C G A T G G T A C C A T G C T A C C A A C G A A G C T T G C A A C G T T G C A A C C T T C G A T G G A T G G T T G C A T C G T A G C A A G G A T C C T T C C A T G G A T G G A A C G A T C G T T C G T A G C A A G G A A G C T A G G A T G C A A C C T A G C T A C C T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G C A T G C T A C G A A C G T A G G T T C C A A G G A A G G T A G G T T G C A A G G A A G G A A C C A T C C T T C C A A G G T T G G T A C G T A C G T A C G A T G C A A G C A A G G T A G C T T C C A T G C A A C G T A G C T T C G T T C G A A G G A A G G T T G G A T C G A A C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G G A A G C A A G C T A G G A T G G T A C C A T G G T A C G A A G G A T C C T A G C T A G G T T G G A A G G T A G G T T G C A A C G T T G G T T G C A A C C A T G G A A G G T A G C A A G C T A C C A T C C A A G C T T G C A T G G T T G C T A C G T A G G T T G G A A G C A T C C T T C G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G T A G G A T G C T A C G T T G G A T C G T T G C T A G G A A C C T A C G T A C G A T G C A A G C T A C C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T G C A T C C A A G C A A C C T A C C T A G G T T C G A T G C A T C G T A C C T A C C A A G C A T G G A A G G T A C C T T G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C C A A G C T A C C A A C G A A C C A A G C T A G G A A G G A T C G T A C C A T G C T T C G A T C C T T C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A C C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T G G A T G C A T G C A T G C A A C C T T C G A T C G A A C G T A C C T T G C T T G C A T G G T T G C T A C G A T C G T T C G T A G G A A G C T T C C A A G C T T G G T A G C T A C C A T G C A T G G T T G G A T G G T A C G A A G C T A C C T T G G T A C G A A G G T T G C T T G C A A G G T A G C T A G C A A C C T A G G A T G C A T G C A T C G T A C C A A G C T T C C T A G C A A G G T A G C A A G C T T G C A A G G A A C G T A C C T T C G T A G C T A C C T A C C T A C G A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C G T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T A C C A A G C A A C C T A G C A T G C A A C C A A C G T +242 A C C T A G G T A C G T T G C T A G C A T C C T A G C T A G G A A G C A A G G A A G G T T C G T A G G A T G G A T G G T T G G T A C C A T G G T T G C T A G C T T G G T T G C T T C C T T G G T T G G T T G G A A G C A T G G T A C G T A G G A T G G A T C C T T C G T T G C A A C C T T C G A A G C T T G G T T C C A T C C T A G C A A G G A A C C T T C C T T G G T A G C A A C G A A G C T T G G T A G C A A G C A A G C A A G G T T G C A A G C T A G C T A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C G T T C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A C C T A G C A A G C A T C G T A C C T T G G T A C G T T G G A A G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T G C T A C C T A G C T T G C T A G C A A G G A A G C A T G C T T C C T T C C T A C G T T C G A A G C A T G G A A C C A T G G A A G C T T G C A T G C A A C C A A C G T T G C T T G C T T C C A T C G A A C G A A C G A T C G A T G G A T G G A T G C T T C C A A C C T A C G A T C C T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C T A C C T T G C A A C G A A G C A T C C A A C G T A G C A A C C T A C G T T C G A A G G T A C C A T G C T T C G A T G C T T C G A T C G A A G C T A C G A A C C A A G G A T G C T T G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G G A T G C T T G G A T C C T T C G T T C C T A G G A A G G T A G C T A C G T T G G T T G C T T G G T T G C T A G G T A C G T T C G A T G C T T G C T T G C T A C C A A G C A T G G T A C C A A C C T A C G T A G C T A C C T A C G T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C A A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G C T A G C A A C C A T C C T T C C A A G C T T C C T A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T C G A T C G T A G C T A G G A A G G A A C C T A C C A T C G T T G C A A C G T A C C A A G C A T G C A T C G A T C C T A G G A T G C A A G C A T G G A T C C T A C G A A G G A T G C T A C C A A G C T T G G A A C C A T C C T T C C A A C C A A G C T T G C T T C C T T C C A A G G T T G C T T C C T A G G A A C G T A G C T T G C A A C G T A C C T A G C T A G C A A C G T A C C T +243 A G C T A C G T A C G T A G C T A C C T T G G A A G G T T G G T A C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C T T G C T T G C T A G C T T G C A T G G T A C C T T G G T A C C A T G C T A C C A A G G T A C C A T G C T T C G T T G C A A C C T T C G T T G G T T G C T A G C A T C G T A G C A A G G A T C C A T C G A A G G T A G G A A C C A A G C T T G G T A C G T A C C A A C G A A G G T T G C T A C C T A G G A T G C T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G C A A C C T A C G A T G C A A G C T T C C A T C G T A C G A T G C A A G C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C T T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A G G A A G C A T G C A A G C A A C G A A G G A A C C A A G G T T C G T A G G A A G G T T G G A A C C T A G G A A G C T T G G T A G G A T G G A T G C T T G C T A G G T A C G T A G C A A G C T A C C T T G C A T G C A T C C T T G G A T G C A A G G A A G C A A G C A T C G A T C G A T C C A T C C A A G C A A C C T A C C A A G G T T C G A T G C A T C G A A C G T A C G A A G C A T G G A A G G T A C C T T G C T A C G A A C C A A C C T T G C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T A C C A A G C T T C G T T C G A A G C T A C C T T G C T T C G A A C C T T C G T A C G A T C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C C T A G G T T G C A A G C T A C C T A C G A T G C A T G G T A G G A T G C T T G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T T G G T A C G A A C G T A G C A T G C T A G G A A C C T T C G A T C G A A C G A T C C T T G C T A G C T T C G A A C G T A C C A T C C T T C G A A C G A A G G T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G A A G G A A C G A A C C T T C G T A C G A A C G T T C G T T C C T A C C A T C C T A G C T A G G T T G G T T G C A A G C T A C C T A G C T A G G T T C G T A G C T A G C A T G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C C T A C G T T G C A T C G A T C C T A G G T T C G A A C G A T G G A T C C T A C G A T G C T T G C A A C C T T G C T A G C A A G C A A C C T A G C T A C C A A G C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +244 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A C C T T C C T T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T C G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G A A C G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C C T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T T C C A T G G A T C C T A C G T A G C A A C C T A G G A A G C A A C C T A G C A A C C A A C C T T C C T T G C A A G C A T G G A A C C A T G G A A G C T A G C A T G C A A C G A A C C T T G G A A C C A A G G T A G C A A G G T A C G T T G G A A C C T A G C A T G G T T C C T T G G T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A T G C T A G G T A G G T T G C A T G C T A C G T T C G A A G C T A C G T T G C T T C G A T C C T T C G A T G C T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A A G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C G A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G C A T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T C C T A G G T T C C T A G C T A G C A A G C T A C G T +245 T G G T T G G A T G C T A G C T A C C T T G C T A G G T A G G T A C C T A G G T T G C T T G C T A G G T T C G A T G G T T G G T A G C A T G C T T C C T A G C T T G G T T G C A T G C A T G G T A G G A T G C T T C C T T C C A A C C T A G G A A G C A T G C A A C G T T G C A A C C T T C C A A C C T T G C T A G C A T C G T A G C A A G G A T C C A T C C A A G G A A G G A A C C T A G C T T C G T A C C T A G C A A G C A T G G A A G G A A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A T G C A A C G T T G G A A C C T T G G T T C C A A G G A A C G A T G C T A C C T A C G T A C C A A C G T A G G T A G G T A C C A T C C T T C G T A G C T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G C T A G C T T C G T T C C A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G C A T G G A A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C T A G G A T G C T A C C A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A T G G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T C C T T C C T A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C G T T C C T T C C T A C G T T G G A A G C A T G C A T G G A T G C A A G C T T C C T T G C T A C G T T C C T T G G T T G C T A G G T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G A T G C T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C T A G C T A G C A T C G T T G C A A G C T T G G T T G C T A G G A A C G T A G C T A C C A A G C T T C C T A G C T A G C A A C G T A C C T +246 A G C T A G G T A C G T T G C T A C C T T G C T A G C T A G C T A C G T A G G T T G C T T G C T T G G T T C G A T G C A A G G T A G C A T G C T T C C T T G C T T G G T T C C T T G C A T G G T T G G T T G C A A G C A T C G T A C C A A C G T A G C A T C C A T C C T T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A T C C A T G G T T C C T T G C A A G C T A C G A A G C T T C G T A C C A A G G A T G G A A G G T A G C T A C G T A G C A A C G T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T A C G T A C C T A G C A T C G A A C G A T G C T A G G A T G C T T C G T T G C A A G C A T G C T A C C A A C G T A C G A T G C T A C G T A C C T A G C A A G C A T G G T A G G T A C G A T C C A A C G T A C G A A G G T T C G A T G G A A G G T T G G A T C G A A C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C A T C G A A G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G A A G C A A G G T T C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A T G C A T C G A A C C A A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A A C G A T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G G T T C C T T G G A A C C A A G C A A G C A A G G A T G G T A G G A T G C T T G G A T G G T A G G A A C G T T C C T T C C A A G C A T C C T A G C T A G C A T G G A T G C T T G C T A C C T A G C T A G G T T C G T A C G T A G C T T G C A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A C G T A C C A A C C A T C G A T C G A T C C T A G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C T A C G A T G C T T G G A A C C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G G A T G C T A G C A A C G T A G C A T G C A A G C A A C G A A G C T A C C A A G G T A C C T +247 A G G A T G G A T G C T T G C T A C C T A G C T A C G T T G C T T G C A T C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T A C G T T C G T A C C A A C G T T C G T A G G A A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C C T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A G G A A C C A A G G T T C C A A C C A T G G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C A T C C T A C G T T C C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +248 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C A A G G T A C C A A G C A A G G A A G G A A C G A T C C T T C C T T G G T A C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T A G C A A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T T G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A G G A T C C T T C C A A G C T T C C T A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T C G A T G C A A G C T T G G A A G G A A C C T T C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T G C A A C G T A C C T A G C T A G C A A C G T A C C T +249 A C G A T G G A T G C T T G C T A C C T A G C T A C G T T G C T T G C A A C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T A C G T T C G T A C C A A C G T T C G T A G G A A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A G C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C A A G G T A C C A A G C A A G G A A G G A A C G A T C C T T C C T T G G T A C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T A G C A A G G A T C C T A G C A A G C T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T T G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T A C G A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G C T A G G T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A A G C T A C G A A G C T T G C T T G C T T G G T T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C A T G G A A G G A A G C T A C C A A G C A A C C T T G G A A C C A T G C A A G C T T G G T T G G T A G G A A G C A A C C T T G G T A C G A A C G T T G C T T C C A A G C A T G C T A C C T A G G T T G G T T G C A T G C T A C C T A G G T T C G T T C G T T C C T A G C T T C G A A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C T A G C A T C G A T C C A T G C A A G G A T G C A A G G A T G G A T C G A A C G A T G C T T G C T A C G A T G C T A G G A A G C T A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G G T T C C T T G C T A G C T A C G T A G C T A C G A A C G A A C C T A G C T A G C A A C G T A C C T +250 A G C T A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T T C C T T C G T A G G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T T C G A A G C T T C G T T G C A T G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A C C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T T C C T T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G C T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A G C T A C G A A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C T A G C T T G G T A C C T T G C A T C C T A C C A A C C T A C G T A G C A T G G T T G C T A C G A T C C T T G G A A G C A A G C T A G C A A G C T T G C T T G C A A G C A A C G T T C C T T G G T T G G T A G G A A G G A T G G A T G G T A G G A A C G T T C C T A C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G G A T C C A T C C A A G C A T C G T T G C T A G C A T G C T A G C T A C G T A G G A T G C T A C C T T G C A T G G A A G C A T C C T T G C T A C C A A C G T T C C T T C G T T G C A A G C T T G C T T C C A A G C A A C G T A G G T A C C A A G C A A C C T A G G T A G G T A G C A A C G T +251 A C C T A G G T A C G T T G C T A G C A T G C T A G C T A G G A A G C A A G G A A G C T T C G T A G G T T G G A A G G T T G G T A C C A T G G T T G C T A G C T T G G T A G C T T C C T T G G T T G G T T G G A A G C A T G G T A C G T A G G A T G G A T C C T T C G T T G C A A C C T T C G A T G C T T G G T T C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A C G A A G C T T C G T T G C A A G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C A A G G T A C G T A C G A T G C T A C G T T C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T G C T A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A C G T A G C A T G G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T C C T T C C A A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T G C T T C C T T C C T T C C T A G G T A G G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T G C T T G G T A C G A A C G T T G C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T T G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C C T A C C A T C G A A G G A A G C T A G G T A C C A A G G T T C G T T C G A A C G A A G C T T G C T A C G A T G C A A G G A A C C A T C C T T G G T A C G A A G C T T G G T T C C T T C C T A G G T T G G T T C C A A G C A A C C T T G C T A G G A A G C A A C G T T G C A A G C A A C C T A G C A +252 A C C T A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T T C C T T C G T A G G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G T A G G A T C G A A G C T T C G T A G C A T G C A A G C A A G G T T G C A A C C T A G C T A C C T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A A G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A C C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C A T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G C T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T T G C T A C G A A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C T A G C T T G G T A C C T T G C A T C C T A C C A A C C T A C G T A G C A T G G T T G C T A C C A T C C T T G G A A G C A A G C T A G C A A G C T A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A C G A T C G T A G C A T G G T T C C T T C C T A G C T T C C A A G C A A G G T T C G A T G C T T G C T A C C T A G C T A G G T T C G T A G C T A G C T T C G A A G C T A G G A A G C T A G C T T C C A T C G T T G C A A G C A A C C T A C C A T C G A T C G A A G C T T G G A T G C T A G C A T G C T A G C T A C G T T C C A T G C T A C C T T G C T A G G A A G C T T C C T A G C T A C C A A G G T T G C T T C G T T G C A A G C T T G C T T G C T A G C A A C G T A G C A T C C A A G C A A C G T A G C T A G C A A C G T A G C T +253 A C C T A G G T T C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T A C C T T C G T A G G T T G G T T C C T T G C T A G C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A A C C T T C C A A C G A A G C T A C G A A G C T T C G T T G C A A G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C C A T C C A A G G A A C G A A C G T T G C A T C G T A G G T A C C A A C G T T G G T A C G T A C G A T C C A T C G T A G C A A G C T A C G T T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G A A G G T A G G A A G C T A G C A A C G T T G G T A G C A A G G A T C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G C T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G A A G G A T C C T A G G A A C C T A G C A A C C A T C C T T G C A T G C A T G C A A G G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A A C G A A C C T T C G T A G C T A C C T A C C T A C G A T C C A T C C A T G C T A G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C A T G C T T C C A A G C T T C G A T C G A A C C A A C G T A C C T A C G T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A C G A A G G A A C C T A G C T A G C A A C G T A C C T +254 A C C T A C G T A C C T T G C T A C C T T G C T A G G T A G C T A C G A A G G T T G C T T G C T T G G A A C G A A C C T A G G T A C C A T G C T T G G T A G C T T G C T A G C A T C G A T G G T A C G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T T G C A T C G T T G G T A G C T T G C T A G C A A G G A T G C A A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T C C A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A C C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C T T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G A T G C T T C G A T C C T T G C T A G G T A C G T A G C A A G G A A G C T T G C T A C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T C C T T C C A A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T T G C T A C G A A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C T A G C T T G G T A C C T T G C A T C C T A C C A A C C T A C G T A G C A T G G T T G C T A C G A T C C T T G G A A G C A A G C T A G C A A G C T A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A G C T T G G T A C G A A C G T T G C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T G C A A G C T A C G A T G C A T C C A T C G A A G C A T C G T T G C A A G G A T G G T T G C T A C G A A G C T A C C A A C C T T G C T A G G A A G C T A C C T T G C T A C C A A C C T T G C T T C G T T G G A A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +255 A G C T T G G A T G C T T C C T A C C T T C G A A G G T A C G A A G G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A G C A T G C A T G C T A G C T T G G T T G C A T C G A T G G T A C G T T G C T A G C A T C G T A C C T A G G A T G G A T G C A A C G T T G C A A G C T T C G A T G G T A G G T T G C A T C C T A C C T T C C A T C C T T C C A T C G A A G C T A C C T A G G T T G G T A G C T T G C T A C G A A G G T T G C T A G C T A G C A A C C T A G C A A G C T A G C T A G G A A C C T A G C A A G G A A G G T A C C T A G C A A G C A A C C T A G C A T C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A G G A T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T G G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G G A A G C T T C G T T G G T A C G A A G C T A G C A A G C A A C G A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T A C G T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A C C T A C G A A C C A T G C T A C G A A G C A T G G T A C G T T G C T T C G A T C C T T G G A A C G A A G C T A G G A T C C T A G G A T C C T A C C T T G C A T C C A T G G T A C G T T G G T T G C A A C C A A G G T A G C A T G G A T G G T A G G A T G C T A C G A T C C T T C G T A C C T A G C T T G G A T G C T T G C T T G G T A C C T A G G T A C C T A G G T A C G T T C C T A G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T G C A T G C A A C C A T G C A T C C T A G G A T G G T A C G A A G C A T G G A A C C A A G G T A C G T T C C T T G C A A C G T T G C T A G C T A G C T T G G T T G C A T G C T A C C T A G C T A G G T T C G T A C C T T G C T T G C T A G C T A G G A A G G A T C C T T C C A T C G T T G C A A C C A A C C A A G C T T C C A T C C A T G C T T G G A T G G T A C C A A G C T T C G A A C G A T G C T T C C A A C C T T G C T A G G A A G C A A C C T T C C A A C C A T C C T T G C T T C G T T G C A A G C T T G G T T G C T T G C T A C C T A G C A A C C T A G G A A C C T A G G T A G G T A G C T A G C A +256 A G G T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T G C T T G C T A G G T T C G A A C C T A G G T A C C A T G C T T G C T T G C A T G G T A G C A T C C T T C G A A G G A T G G T A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A G C A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A C G T A C G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T A C G A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G C T A G G T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A C C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A A G C T A C G A A G C T T G C T T G C T T G G A T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A A C G A A G C T A C C T A C C T T G C A T G C A A C C A T G C A A G G T T G C A T G G T A G G A A C G A T C G T T C G T A C G A A C G T T G C T T C C A A G C A T G C T A C C T A G C A T C C T T G C T T G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C G A T C C A T C C A T G C T T G G A T G C A A C C A T G G A T C G T A C G A A G G T T G C T A C G T T G C T T G G A A C C A T C C T T G C T A C C T A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +257 A C C A A G G T A C G T T G C T A C C T T G G T A G G T A C G T A C G A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T G C T A C C A T C C T A G C T A G G A A G C T T G C A A C G T T G C A A G C T T C G T T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C T A G C A A G C T T C G T A G C A A G C A A C C A A G G A T G C A A G C T A G C T A C C T T C C A A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G C A T C C T T G C A A C G A A G G T T G C T A C G A T G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A G C A T C G A A G C T T G G T A G G T A G C A A C C T T G G A A C G A A C G A T C C A A C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A T C G T T C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G G T T C C A A G G A A G G T T C G A T G C T T G C A T C G T T C C T A C G A A G G T A G C T A C G A T G C T T C G A T G C T T C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C C A A G G T T G G T A G G T A G G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T T G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G A A C G A T G C T T G G A T G G A T G C A T G G T A G C T A G G T A C G T T G G A T G C A A G C A T G C T T C C T T G C A T G G T A C C A A G C T A C G T T G C A T C G T A C C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G A A G G A T C C T A G G A A C C T A G C A A C C A T C C T T G C A T G C A T G C A A G G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A A C G A A C C T T C G A A G C T A C C T A C C T A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +258 A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G C A A G C A T C G T A G C T A G G A T G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C G T T C C T A G C T A G C T A G G T T G C T A G C T T C C A T G C T A C C T T C C A T G G A A C G T A G G T A G C A T G G A A G G A A G G T T G G T T G C T T G C A A C C A T C C A T C C A A G G T T G G T A C G T T C G T T G C T A G C A A G C A T G G T A G G T A C G A T C C A A C G T A G C T T C C T A C C A T C G A A C G T T C G T A C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G A T G G A A C C A T C C T A G C T A C C A A C G A T G C A T C G T T C C A T G C T A C G T T G G A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C A A C G A A C G T T G G A T C C A T G G A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T G G A T G C A T C C T A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G A T G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C T T C C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T A C C T T G G T A C G A A G C T T C C T A C C A A G C A A G C T A G G T T C G A A C G T A C C A T G C A T C G A A C C T A C G A T G C T T G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T T C G T A G C A T G G A T C G T A G G A T C G T T C G A A C C T T C G T T G C T T C G T A G G T T G C A T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +259 T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G T T C C T A G G A T G C T T G C T T G G A A C G T A G C T A G G T A G C T T C C A T C G A A C C T T G G T A G C A A G C A T C G T A G C T T G C T A G C A T C C T A G C T A G G A A C C A T C C T T C G A T G C T A G C T T C G T T G G T T G C T T C C A T C C T A G C T T C C A T C C A T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G C T A C C A A C G A A G G T A G G T T G C T A C C T T G C T T C C A T G C A A C C A A G G T T G G T A C G T A C G A A G G A T G G A A G C A T G G T A G G T A C G A T C C A A C G T A G C T T C C T A C C A T C G A A C G T T C G T A C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G A T G G A A C C A T C C T A G C T A C C A A C G A T G C A T C G T T C C A T G C T A C G T T G G A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C A A C G A A C G T T G G A T C C A T G G A T C G T T C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G G T A C C A A G G A A G C A A C G A T G C T T G C T T G C A T C C T A C G A A G G A T G C T T G G A T G C T T C G A T G C T A C C T A G G T A C G T A G C A A G C A A C C T T G C A T C C A T C C T T C C A T G G T T G C A A C G T T C C A T C G A A G G T T G C A T C G A A G C A A G C T A G C A A C C T T C C T A G C A T C C T T C G A T C G A T G C A T G G T A G C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G T A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G G A A G C A T C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G T A G G T T G C A A C C T T C C T T G G A T C C T T C C T A G G A T G C A A G G A T C C T T C C T A G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C G T A C G T A C G T T G C T A G C T T G C A A G C T T G C T T C C T T G C T T C G T T G G A T C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C C T T G C A T G C T A C C A A C G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +260 A C G T A G G T A C G T T G C T A G C T T G C T A G G T A G G T A C G A A G G T T G C T T G C T T G G T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G A A C G A T G G T T C C T T G C T A C C A A C G A A G C T T G G A A C G T T G C A A G C T T C C T T G G T T G G T T G C A T C C T A G C A T C C A A C C T T C C T T G G T A G C T A G C A T C G T T C C A A G C T A C C A A G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G G T T G C T A G C T T C C A T G C T A C C A T C C A T G G A A C G T A G G T A G C A T G G A A G G A A G G T T G G T T G C T T G C A A C C A T C C A T C C A A G C T A C G A A G C T T G G T A G G T A G C A A C C T A C C T T C G A A C G A T C C A A C G T A G C T T C G A A G C A T G G A A C G T A C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G G A A G C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G G T A C C A T G G T A C G A A G G A T C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G C A A G C T A G C T A C C T T G G A A G C A A G G T T C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G G T T C C T T C C T T C G T A C C A A G G A T G C A T G G A T C C A A G G A A G G T T C G A T G C T T G C A T C G T T C C T A C G T A G G A A G C T T G G T T G C A T C G A T C C T T C G T A G G T A C G T T G C T T C C A T G C A T C G T A C C A T C C T T C C T T G C A A C C A A G C A A C C T A C G T A G C T A G C A T C G A A G C A A G C T T C C T T G C T T G G T T C G A A C C T A C G T A C C A T C C T T G G A T G C T T C C A A C G T A C G A A C C A A C G A A C G A A G G T A C C A A C C A A G C A T G C T A G C T A C G T T C G T A G G A A C C A T G G T A C G A T G G T A C C T A G G T A G C A T G C T T C G A A G C A A G G T A G G A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C A T G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T A C C T A G G T A C C A T G G T T G C T A G G A A C G T T C C T A G C T A G C A T G G T A C C T T G C A T C G A A C G A T C C T A G C T T G C A T G G A T G C T A C C A T C G A T C G A A G G A A G C T A G C A A G C T T G C T T G G A A C C A T G C A A G C A T G C A T G G A A C G A A C C T A C C T T C G T A C G A A C G T T G C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G T A C G T A C C A A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T A G C A A G C A T C G T A G G T A G G T A G C T A C G T +261 A C C T A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T T C C T T C G T A G G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C G T T G G T T G C T A G C A T C G T A G C A A G G A T C C T T C C A T C G A T G C T A C C A T G G T T C G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A C G T T G C T A G C T A G G T A G C T T C G T A C C T T C C A T G C T A C G A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C A T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A C C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C G A A C C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T G C A A G G A T C C T T C C A A G G T A G C T T G G A A G C T T G G A T G C T A G G T A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C T T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G G T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G G T T G G T T G C A A G C T T C G T A C G A T G C T T C G T A G G A T C G T T G G A A G C T T C G T T G C T A C G A A G G T T G C T A C G A T G G T T G C A T C C T T G C T T G G T A C G T T C G T A G C A T G C T A G G A A C C T T G C A T C G A A C G A T C C T A C G T A G C T A C G T A C G T A C C A T C C A T G G A A G G A A G C T A G C A A G C T T G G T T G C T A C C A T G C A A G G T T G C A T G G T A G G A A G G A A G C T T G G T A C G A A C C T T C C T T C C T A C G T T G G A A G G T T G C T T G G A A G G A T G C A A C G T T C C A A G C T T G C T A G C A A G C T T C G T A G C A T G C A A G G A A C C T A C C T T C G T T G C T T C C A A C C T A C G A T C C A T C C A A G C A T C G T T G C T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G C A A C C T A C C T A G C T A C C A T C G T T C C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T G C A A G G A T C C T A G C T A G G A A G C T A G C T +262 A C C A A C G T A C C T T C C T A C C T T C G A A G G T A C G T A G G A A G G T T G C T T G C T A C G T T C G A T G C A T G G T A G C A T G C T T G C A A C C T T G C T A G C A A G C A T G G T T G G T A G G T A G C A T C G T A C C A A C G A A G C A T G G A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T T C G A A G C T T C G T T G C A A G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T T G G T A C G T A C G A A G C A A G G T A C G T A C G A T C C A A C G T T G C T T C G T A C G T A G C A A G G T T G G T T G G T T C C T T G C T T G G T A G C T T C G T T C C A T G G A A G C A A G G A A G G A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A T C G A T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G G A A G C A A C C A A C G A A C C T A G C T A C C T A G C A A G G T T G C T A G G A A G G T A G C A T C G T T C C A T G G A T C C T A G C T A G G A T G C T T G C A A G C T A G C T T G C A T G C A T C C T T G G A T G G T A G G A A C G T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C A T G C T T C G A T C G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T G G T A G G A T G C T A G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C T A G C T T G G T A C C A T G C A T C C T A C C A A C C T A C G T A G C A T G G T T G C T A C G A T C C T T G G A A G C A A G C T A G C A A G C A A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A G C T T G G T A C G A A C G T T G C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G C A T G C A T C C A A G C A T C G A T C G T A G G A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G G A A C C T T G C T A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A C G A A G G A A C C T A G C T A G C A A C G T A C C T +263 T G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G A A C G A T G C A A G C A T G C T A G C T A G G A A G C T T G C A A C G T T G C A A G C T T C G A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C T A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C C T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G A T G G A A C C A T C C T A G C T A C C A A C G A T G C A T C G T T C C A T G C T A C G T T G G A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C A A C G A A C G T T G G A T C C A T G G A T C G T T C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G G T A C C A A G G A A G G T T C G A T G C T T G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T T C G T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G T T G C T T C C A T C G T A C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +264 A C C T A C G T A C G T T G C T A C C T T G C T A G G A A G G T A C G A A G G T T G C T T G C T T G G T T C G T A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G G T A G C A T C G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C T T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C G T T C C T A G C T A G C T A G G T T G C T A G C T T C C A T G C T A C C A T C C A T G G A A C G A A G G T A G C A T G G A A G G A A G G T T G G T T G C T T G C A A C C A T C C A T C C A A G C T T C G A A G C T T G G T A G G T A G C A A C C A T G G T A G G T A C G A T C C A A C G T A G C T T C C T A C C A T C G A A C G T T C G T A C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T A C C A T G G A T C C T A C C T A G G T A C G T A G C T T C C A T G C A T C G T A C C A T C C T T C C T T G G T T G C A A C G T T C C A T C G A A G G T A G C A T C G A A G C A A G C T T C C T T G C T T G G T T C G A T C C T T C G A T C G A T G C A T G G T A G C A A C C A T G C T T C G A T C G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C A T G G A A G G A A G C T A G C A A G C T T G C T T G C A A G C A A C G T T C C T T G G T T G G T A G G A A G C A T G G A T C G T A G G A T G G T T C C T T G C A A C G T A G C T A G C A T G G T T G G A T C C A A G C A A C G T T G C T T C G A A C C T A G G T T G C T A C G A A G C T A C C A A G G A A G C T A C C T T C G T T G C A T C C T T C C T A C C A T G G A A G G A A G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T T G C A A C C T A G C T A G C A A C G T A C C T +265 A G C T A G G A T G C T A G C T A C C T T C G A A G G T A G G T A G G A A G G T T G C T T G C T T G G A T G G A T G C T A G G T A G C A T G C A A C G T T G C A T G G T T C C A A C C T T G G T T G G T T G C A A G C A T C G T A G C T A G G A T G C A T G G A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A A C G A T G C T A C G A A G C T T C G T T G C A A G G A A G C A A G C T T G C T A C C T A C C A A C G T T G G A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A C C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T A C C A A G G A T G G A T G C A A C G A T C G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C A T G G A T G C T A C C T A G C T A C C T A G C A A G G A A C C T T G C A T C C A T C C T T C G T T G G T A G G A T G G A A C G A T G C A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T C C T A G C T T G C A T C C T A G G A A G G T T G G A T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A G G T T G G T A C G T A G G A T G C A T G G T A G C T A G G T A C G T T G G A T G C T A G C A T G C T A C C T T G C A T C C T A C C A A C C T A C G T A G C T T C G T A C C T A C C A T C C T T C G T A G G A A G C T A G C A A G G T T G G T A G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A G C T T G G T A C G A A C C A T C C T T C C T A G G T T C C A T G C A T G C T A G G A T G C T T G C T T C C T T G C T A G C T T C C T T G G T T G C A T G C A A G C A T G C A A G G A A C G A A C C A T G G T A G C T A C C T T C C A A C G A T C C A T C G A A G C T T G G T T G C A A G G A A G G A T C G A A C G A T G C T T G C T A C G A T G C T A G G A A G C T T C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G C T A C C T A G G T A G G T A C C T T C C T A G C A T G C A A C C A A C G T +266 A C C T A G G T A C G T T G C T A G C T A G C T A G G T T G G T A C C A A G G T T C C T T G C T T G G A A G G A A C C T A G G T A G C T A C C T T G C T T G C T T G C T A G C A T G C T T G G A T C G T T C G T A G C A A C G T A C G T A C G T T G C A T G C T T C G T T G C A A G C A T C C T T G G T T G C T T C C A T C C A A C C T T C C A T C C A T C C A T G G T A G C T T C G A A G C T T C G T T G C A T G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G A T G G A A G G T A C G A T G C T T C G T A G C T T C G A A C G A A C C A T C G A T G G A A C G A A G C T T G C A T G C T T G C T T C G A A C C A A C C A A G C A A C C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G T A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C A T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G C T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A T C G A T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T A C G A T C G T A G G A A G C A T C G T A G C A A C C A A G G T T C G A T C C T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G T A G G A A C C A T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G T A G G T A G C A A G G A T G C T T C C T T C C T T C C T A G G T A C G T A G G T A G C A A G G T T C G T A C G A T G G T T C G T A G G T A G C A A C G A T C G A T C G T T G C T A C G A A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C T A G C T T G G A A G C A T G C A T C C T A C G T A C C T A C G T A G C A A G G T T G C T T C G A T C C T T G G A A G C A A G C T A G C A A G C A A C C T T G G A T C G T T G C A A G G T T G G T T C G T A G G A T G C A A G G T A C C A T C G A T G G T T G C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G G A T C C A T C C A A G C T A G G T A C C A A G G T T C G T T C G A A C G A A C C A T G C T A C C T T G C T A G G A A C C A T C C T T C G T A C G A A G C T T G G T T C C T T C C T A G G T T G G T T C C A A G C A A C G T T G C T A C G A T G C A A C C T A G C A A C C A A C C T A G C A +267 A G G T A C C T A C G A T G C T A C G T A C G T A G G T A C G T A G G A A G G T T G C T T G C T A G G T T C G A A G C A A G G T A G C A T G C A T G C T A G C T T G C T A G C A A G C A T C G T A G G A T G G T A G C A T C G T A C C A A C G A A G C A T G G A A C G T T G C A A G C A A C C T T G C T T C G T T G C A T C G T A G C T T G C A T C C T T C C A T C G A T G C T A C C A T G G T T C G T A C C T A G C A A G C A A G C T T G C T A G C T A G C A A C G T A C C T A G C T A G C T A G G T T G G T A C C T T C C A T G C T A G G A T G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A A C G T T C C A A C G A A C G T T C G T T G C T T G G A A G G T A C G T A G G T A C C T A G G T T C G A T C C A A C G T A G C A A G G A A G G T A G C A A G G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G C A A G G A A G C A T C G A A C C T A C C A A G G A A C G A A G C A T C G A T G G T A C C A A C C A A C G T T G C A T G C A A G G T A C C T T C C A A G G T A C C T T G G T A C C T A G G A A G G T T C G T T C G A A G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A A G C A A C C A A C G A A C C T A G C T A C C T A G C A A G G T T G C T A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G G T A C C T A G G A A G C T A C C T T G C A T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T C C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T A G G A A C C T T C G T T G C T T C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T T G C A A G G A A C C T T G C A T C G A A C G A A C C T A C G T A G C T A C G T A C G T A C G A T C C A T G G A T G G A A G C T T C C A A G C T T G C T T G C T A C C A T G C A A G G T T G C A A G G T A G G A A G G A A G C T T G G A T C G A A C C A T C G T T C C T A C G T T G G A A G C T A G G T T C G T T C C A A G C T A C G A A G C T A G C T T G G T A G G T A C C A T G G A A C C T A G C A A G G A A C C T T C C A T C G A A G C T A C G A A C C T A C C A T G C A T C C A A G C A T C G T T G C A A C G A A G G A T C G A A C G T T C C T T G G T T C C A T C G T A G C A A G G A A C C T A G C T A C C A T C C T T C C T A C C T T G C A A G C T T G G T T G C T A G C T A C G T A G C T T G C A A G G A T C C T A G C T A G G A A G C T A G C T +268 A C C A A C G T A C C T T C C T A C C T T C G A A G G A A C C T T C C A A G G T T C C T T G C A A C G T T C G A T G G T T G G T A G C A A C C T T G C A A C C T T G G A T C C A A G C T T G G T T G G T A G C T A C G A T C C T T G C T A G G A A C C A T G G T A C G T T G G A A C C T T C G T A G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A G C A T C G T T C G T A G C T A G C A A G C A A G G A T G C A A G C T A G C A A C C T T G C T A G C T A G G T A G C T T C G T A C C T T G G A T G C T A C G A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C A T G C T T G C A T C C A T C C A A C C A A C G A A C G A T G C T A C C T A C G T A C G A A G C A A G G T A C G T A C G A T C C A A C C T T G C T T C G T A C G T A G C A A G G T T G G T T G G T T C C T T G C T T G G T A G C T T C G T T C C A T G G A A G C A A G G A A G G A T C G A A C C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T T C G T T G C A T G C A A G C A T C C T T C C A A G G T A G C T T G G A A G C T T G G T T G C T A G C A T C G A T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A C C A T G G A T C C T A G C T A G G A T G C T T G C A A G C T A G C T T G C A T G C A T C C T T G G A T G G T A G G A A C G T T C C A T G G A A G C T A G C A T C C A A C C A A G C T T C C T A G G T T C G A T C G T A C G A A C C A T G C A A G C A T C C A A G C A A G C T T G C T A C G A A C G T A C C A A C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A G C A A C C T A C G T T C C A A G G T A C C A A G C A T C G A T C G A A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G G A A C C T T G G T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A C G A T G C T A C G A T G G T A C C T A G G T T G C T T G G T A C G T T C G T A G C A T G C T A G G A A C C A T G C A T C G A A C G A T C C T A C G T T G G A T C G T T G G T T C C T T C G A T G G A A G G A A G C T A G C A A G C T T G G T T G G T A C C A A C G T T C C T T G C A T G C T T G C A A C G A T G G A T C G T A C G A A C C T T C C T T C C T A C G T T G G A A G G T T G C T T G G A A G G A T G C A A G G T T C C A A G C T T G C T A G C A A G C T T C G T A G C A T G C A A G G A A C C T A C C T T C G T T G C T T C C A A C C T A C C A T G C A T C C A A G C A T C G A T C G T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G G A A C C A T C C A T G C A A C C A A G C T T G C T T C C T T G C T A G C T T G C T T C C T A G C A T C C T A G C T A G C A A G C A A C C A A G C T A C C A A G G T A C C T +269 A G C T A G G A T G C T T C C T A C C T T C G A A G G T A C G T A C C A A G G A T G C T T G C T T G G A A G G A T G C T T G G T A G C A A C C T T G C A A C C T T G G T T C C T T G C A T G G T T G G T T G G T A G C A A G G T A C C A A G G T A G C A T G G A T C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G T A G G A A C G T A G G T T G G T A G C T T G C A A G C A A G G T T G C T A G C T A C C A A C C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T A C G A A G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A T C C A T G C A A C C A A G G A T G G T A C G T A C G A A C C T A G G A A C G T T G G A A G G T A C G A T G C T A G C A A G C T T C C A A G G A T C C A T C G A T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A G G A A G C A A G C A A C C A T C G A A C C A T C C T A G G T T G G A A G C A A C C A T G G T A C C A A C C A A C G T T G C A T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G G T A G C A A C C A A G G T A G G A T G G A A G C T A C C A T G G T A C C T T G C A T C G T A G C A A G G T A G G T T G G T T C C A T C C T T G G T A C C A A G C A T G G A A G G A A C G T A G C T A G C A A G C T A C C T A G C A A G G T A C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C C T T C C T T C C T A C C T T G C A T G C A T C C T A C G T T G G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C T A C G A A C G T T G G A A C C T T G G T A G C T A G C A A G G T T C G A T C C T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T T G C A T C G A A G C A T C C T T G G A T C G A T G G T A C C T T G C A A C C A A G C T T C G A A G G A A C G A A C C A T G C T T C G A A C C T T C G A A C G T T G C T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T A C G T A C C T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C T A C G A T C C T T C G A T C C T A G G A A C G A T G C T A C G T T G G T A C C T A G G T T G C T T G G T A C G T T G G A T C C T A C C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C T T G G T T G C T A C C A T C C T A G C A A G G A A G C T T C C A A G C T T G G T A G C A A C G A T G C A A G C A A G C A A G G T A G G A T G C A T G C T T C G T T C G T A G C T T C C T T C C T A G G T A G C T A G C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T A G G T A G C T T C G T A G C A T G C A A G G A A C G A A C G A T C G T T G G T A G C A A C C T A C C A T C C A T C C A T G C T A G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C T A C C A T G C T T G G A A G G A T C G A T C G A A C C A A C C T A G C T T C G T T C C T A G C T T G C T T G C T A G C A A C C T A G G T A G C A A G C A T C G A A G C T A C C A A G G T A C C T +270 A C C T A G G T A C G T T G C T A G C A T C C T A G C T A G C A A C C A A G G A T G C T T G C A A C G A T G G A T G C T T G G T A G C A T C C A A C G T A C C T A G C T A G C A A G C A T C G T A G C T T G G T T C C T T G C T A C C A A G C A A C C A T G C T T C G A T G C A A G C T T C G T T G C T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C G T A G G T T G G T A G C T T G C A A G C T A G G A T G C T A C C T A G C T A C C T T G C A A G C T A G C A A G G T T G G T A G C T A G G T T G C T A C C T A G C T A G G A A C C A A G C T T C C A A C G A A G C T A G G A T G C T T G G T T G C A A G C A T G C T A C G A A C G T A C G A T G C T T C G T A G G T A G G A A C C T A G G A A C G A A C G A T G C A A G C A T G C T A C G A A C G A T C C A A C C A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A G G A T G C A A G G T A G G A A G G A A C C T A G G T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G G A T G G A T G C T T G C T A G G T A C G T A G G A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A G C A A G G A A C C T A C G A T C G A T G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C A T C C T T G G A T C G A T G G T A C C T A G G T A G C A T C C T A G G A A C G A A G G T A C C A T G C T T C G A T C C T A C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T T C G T T G C A A G G A A C C T T C G T A C C T A C G A T G G T T G C T A G G A A C G T T C C A T C C T T G C T A G G A A C G A A C C T A C C T T G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A A G G A T G C T A C C A T C C A T G G A A G G A A G C T A C C T T G C A A C C T A G C T A C C A T G C A T G G T T G G A T G G T A G G A A G G A A C G A T C G T A G G A A G G A T C C T T G C T A C G T T C G A A G G T T G C T T G G A A G G A T G C A A C G T T C C A A G C T T G C T A G C A A C G T T G C A A G C T A G C A A G G A T G G A A C C A T C G T T G C A A C G A A C C A A C G A T C C A T C G A T G C T A G G A T G C A A C G T T G G A T C C T A C C A T C G A T G C T A C C T A G C A T C C A A G C T A C C T T C C T A C C T A G C T A G C A T C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +271 T G C A A C G T A C C T A G G A T G G A A C G A A G G T A C G T T C C T A G G A T C C T T G C A T G G A T C C T A C G T T G G T A G C T T C C A T C G A A C C T T G C T A G C A T C C A T G G T A C C T T G G T A G C T T G C T A C C A A C G A A C C A T C C T T C G A T G C A A G C A T C C T T G G T T G C T T C G A T C C T A G C A A G G A A C C A T C C T T G G T A G G A A C C A T C G T T C C A A G C T A C C A A G C A A G C T T G C T A C C T A C C A A G C T T G C A A G C A A C G T A G G T T G G T A G C T T C C A A G G T A G G T T G C T T G G A A G G A A G C T T C C A A C C A T G G T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G T A C C T A G C T T C G A A G G A T G G A A G C T A C C T T C G A A C G A T C C A A C G T A G C T T C G A A G G T A G C A A C C T T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T T G G A A G C A A G G A A G G T A G G T A G C T T C C T A G G A A G C A A G C T A G G A T G G T A C C A T G C T A C G T T G C A T G C T A G G T A G C A T C G A A G G T A C G T A C G T A C G T A G G A A G C T T C C T T C G A T C C T A G C T A G C T T C G A T G G T A C G T T G C T T C G T T G C A A C G T A G G T T G G A A G C T T C C T T G G T A C C A A G C T A G G A T G C A A C C A A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T T G G T A G G A T C C A T G C T A C G T A G C T A C C T A G G A A G G A A G C T T G C A A C C A T C C T T C C A T G C A A C C A A G C A A C C T A C G T A G C T T G C A T C G A A G C A A G C T A G C A A C C T T C C T A G C A A C C T A C G T A C C A T C C T T G G A T G C T T C C T T G C T A C G T A C C A A C G A A C G A A G G T A C C A A C C A A G C A T G C T A G C T A C G T T C G T A G G A A C G T T C C A T G G A A G G T T C G T A G G T A G C A A G C T T C G A A G G A A G G A A G G T T G C T T G G A A C C T A C G A T G G T T G C T A G G A T C C T A G G A T C C T A C C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C C T A C G A T G G T T C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T T G C T A C C T A G G T A C C T A G G T A G C T A G G A A C G A A C G T A G C T A C C A T G C T A C C T A G C A T G G T T G C A A C C A A C G T T G C A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A T G C T A C C T T G G A A C C A T G C A A G C A T G C A T G G A A G G A A G C A T G G A T C C T A G G A T G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G G T T C C T T G C T T C G T T C C T T G G T T G C A T C G T A G C A T G C A A C G T A C C T T C C A T C G T T G C T T C G T A C C T A C G A T C C A T C G A T C C T T G G A T G C T A C C A T G G A A C C A A C G T A G C T A C C T A C C A T C C T A G G A A G C A A C C T T C G T A C C A A C C T T G C T A C C T T G C A T G C T T G G A T G C T A G C A A C G T A G G T A G C A A C C T T C G T A G G T A G G T A G C T A C G T +272 A G G T A G G T A C G T T G C T A G C T T G C T A G G T A G G T A C C A A G G A T G C T T G C T T G G A A C G A A G C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T G G T T C C T T G C T A C C A A G C A A C C A T G G T T C G A T G C T A G C T T C C T T G G T T G C T T C C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A G C T A G C T T C G T A C G T A G C A A C C A A G G A T G C T A G C T A C G A A C G T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G G T A C C A A C G A A G G T A G G T T G C T A G C T T G C T T C C A T G C A A C C A A G G T A G G T A C G T A C C T A G G T A C C A A C C T T G G T A G G T A C G A T C C A A C C A A G C T T C G A A G C A T G G A A C G T A C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G G T T C G A A G C A T C C A T G G T A C C A T G G T A C G A A G G A T C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G A A G C A A G G T T C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G G T T C C T T C C T T C G T A C C A A G G A T G C A A G G A A C C A A G G A A G C A A C G A T G C T T G C T T G C A T C C T A C G T A G G A A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C G T A G C A A G C T A C C T T G C A T C C A T C G T T C C A T G G T A G C A A G G A A C C A T G C A T G C T T G G A T C C A A G C A A C C T A G C T T G G T T C G A T G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A C G T T C G A A G G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G C T T G C A A G C A A G C A T C C A T G G T A C G A T G G T A C C T A G C A A C C A T G C T T C G T A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G A A G C A T C G A A C C A A G G A A C G T A C C T A G C A T C C A T G G T A C G A T G G T A G C A A C C T T C C T T G G A T C C A T C G T A G G A T C G T T G G A T C C T T C C A A G C A A G G A A C G A T G C T A C C A A C G T A C C A T C C A T G C T A G G A A C G T T C C T A G C T A G C A T G G T A C C A T G C A T C G A A C G A T C C T A G C T T G C A T G G A T G C T A C C A T C C T T C G T A G G A A G C T A G C A A G C T T G C T T G C A T C G T T G C A A G G T T G G A T G C T T G C A A C C T A C C T T G G T A C G A A C G T T G C T T C G T A C G T A C G T T G C T A G C T T G C A A G C T T G C T T C C T T G C T T C G T T G G A A C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C C T T G C A T G C T A C C A A G C A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G T A C C T T C C A T C G T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T T G C A A G C A A C C T A G C T A C C A A C C T A G C A +273 A C C T A C G T A C G T T G C T A C C T T G C T A G C T A G G T A C G A A G G T T G C T T G C T A C G A A G G A A G C T T G G T A G C A T G C A T G C T A G C T T G C T A G C T T G C A T G G T T C C T T C G T A C C A T G C T A C C A A C G A A G C T T G C A A C G T T G C A A C C T T C G A T G G T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G G T T G G T A G C T T G C T A C G A A G G T A G C T A G C T A G C A A C G A T C C A A G C T A G C T T G G T T C C T A G G T T G G A A G G T A G G T A G C T T G G A A G G T A G G T T C G A A C G A T G C T A C G A A G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G A A C G T A C C T A C G A T G C A A C G T A G G A A C G A A C G A T C C A A C G T T G G T A C C A A G G A T C C A T C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C C A T C G A A C G T T C C A T G C A T C G A A C C T A C C T A G G A A G G A A C G A T G C A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A T G C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C T T C G T T G C A T G G A T C C T A C C T A G G T A C C T A G C A A G C T A C C T T G C A T C C A T C C T A C G T T C G A A C G A A G C T T C C A T G C A T C G A T G C A T C C A A G C T A C C T T G C A A G G T T C G A T C C T T C G A T C G T A G C T T G C A T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A G C A T C C T A C G A A G G A A G C T A C G T T G C A T C G A T C C T A C G A T G C T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A G G T T G C A A G C T A C C A A G C A T C G T T C C T A G G A T G C A A G G A T C C T T C G T T C C T A G G A A G G A A G C T A C G T T G G T T G C A A G G T A G C T A G G T A C G T T C G A A G C T A G C A T G C T T C C T T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A A G G T T C G A A G C T T G G T A G G A A C C A T C G T T C C T A C G T A G C T A G C A A G C A T G C T T G C T T G C T T C C T A G C T A G G T T C C T A G G T A G G T T G C A A G C T A G C A A G G A A C G A T C C T T C G T T G C A A C C A T C C T A C C A T C G A T C G A T G C A T C G A T C G T A G C A A G C T A G C T A C G T A G G A T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G G A A C G T A G C T A C C A A G C A A G C T A G G T A G G T A G C A A C G T +274 A C C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T A C G A A G G T T G G T A G C A A C G A A G G A A C C A T G G T A G C A T G G T T G C T T G C T T G G T A C C T T C C A T G G T T G G T T G G T A G C A T G C T T C C T A C G A A C C A T G C A T C G A T G C A A G C T T C G A A G G T T G C A T C C A T C C T A G C A A G G A T C C A T C C A T G G A T G C T A G G A T C G T T C G T A G C T A G C A A G C A A G G T A G C T A G C T A G C A A C G A T G C A A G G T A G G T A G G T T C C T A G C T T C C A T G C T A C C A T G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C T T C C A T C C T A C G A A C G T T G G A A G C A A C C T A C G A T G C A A C G A A G G T A G G T A C G A T G C A T C G T T G G A A G G A A G G T A G C A A G G T T G G A T C G T T G C T T G C A T G G T T G C T T C C T A G G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T T G C T T C C T A G G T A G C T T G G A A G G T A C C T A C C A A C C T A G G T A G C T T G C T T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A A G G A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T G C T T G G A A G G T A G C A A C G T A G C A T G G A T C C T T C C T A G G T A C C T A G C A A G C T A C C T T G C A T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T G C A T C C A A G C A A C C T A C C T T G C T T C G T T C G A A C C T A C G T A C G A A G C A T C G T A G C A T C C T T G G T T C G A T G G T A C C T A C C A A G G T A G C T A G C T T G C T T C C A A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A A G C A T C G A A C C T A G G A T G G A A G C A T C G A A C C A A G G A A C G T A C C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A G G T A C G A T C C T A G G A T G C T A C G A T C C T T C G T A C C T T G G A A G G T A G C T A C G T A C G A T G C A T G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G A A C C T T C G A T C G A A C G A A C C T T G C T A G C T A C C T A C G T A C C A T C C T T C G A T G G A A G C T A C C T A G C T T G G T A G C A T C C A A C G T T C C T T G G A T G G T A G G A A G C A A G C T T C G T A G G A A C C T T C C T T G C A A C G T T G C A A G C T A G C T T G G A T G C T T C G T T C C T A G G A A G C T T C C T A G G T A G G T A C G T A G G T A G G A A G C A A G G A T C G T T G C A A C C T A C C A A C C T A G C A T C G A T C G A T G C T T G G A T C G A A G C A T G G A T C C T A C G A T G C T T G C A A C C T T G C T T C G T A C C A A C C T T C C T T C G T A G G T T C C T A C G T T G C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A C C A A C C T A G C A +275 A G C T T G G A T G C T T C C T A C C T T G G T A G G T T G G T A C C A A G G A T C C T T G C T T G G A A C G A A C C T A G G T A G C A T G C A T G C T A G C T T G G T T G C A T C G A T G G T A C G A T G G T A G C A T C G T A C C T A G G A A C C A T G G A T C G A T G C T A G C A T C C A T G C T T C C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A A G G A T G C A T C G T T C G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A G G A T C C T T G C T T G C T A C G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C C A A G C T T C C A T C G A T G G T A G G A T G C T T G C T T G C A T C C A T G C A A C C A A C G T A C G T A C C T A C C T A C G T A C C A A C G T T G G T A G G T A C G A T C C A T C G T A G C T T C G T T C G T A G G A A C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G C T A C G T A G C T T C C T A G G T A G C A A G C A T C G T A C C T T G G T A C G T T G G T A G C T A G C T A G G A A G G T A C C A A G G T T C C A T G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G A T C C A A G C A T G G A T G G A T C C T A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T A C G T A G G T T C C A T G C T A C G T A G G T A G C T T G C T T G C A A G C T T G C A T G C A T C C A T C C A T G G T A C C A T G G A A C C T A C G A A G C T A G C T T C C A A G C A A G C T T C C T T G C A A G G T A C G T T C C T A C G T T C C A T C C A T G G A T G C T T C C A T G G T A C G A T G G T A C G T A C G A A G G T A C C T A C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G C A A C G A A G G T A C C T A C G T A G C A A G C T A C G T T C G A A G G T A C C T T G C A T C G A A G C T T C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C G T A G G A T G G T T C G T A G G A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T A C C T A G G T T G C T A G G T A C G T T G G A T G C A T G C T A G G A A C C A T C G A T C G A A C G A T C C T A C G T T G C A T C G T A G G T A C C A T C G A T C G A A C G A A G G T A C C T A G C T T G C A T G C A A C C A T G C A A G G T A G C A T G G A A G G A A G C T A C C T T G G T A C G T T G G T A G C T T C C T A G C A T G C T A C C T A G C A T G G A T G G A A G C T A C C T A G C T A G G T T C G T A C G T A G C T T G G T A G C T A G G A A C G A A C G A A C G A T C G T T G G T A G C T A C G A T G C A T G C A T C G A T C C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +276 A C C T A G G A T G C T T C C T A C C T T C G A A G G A A C C T A C C A A G G T T C C T A G C A A C G A A G G A A C C A T G G T A G C T A C C T T G C A A C C T T G G T T G C A A G C T T G G T T C C T T G C T A C C A T G C T A C C T A G C T A C C A T G C T T C G A T G C T A G C T T C G A A G C T T G G T T C C A T C C A A G C A T C C A T C G T T C G A T G G T A G C T A C G A A G C T T G G T A G C A A G G A A G G A T C G A A G C T A G C T A G G A A C C T T C C A A G G T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T G C T T C C A A C G A A G G T A C C A T C G A T G G T A G G A A G G T T G C T T G C A A C C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A C C A T C G T A C C A T G C T A C G T T G G A T C C T A G C A T C C T T G G A A G G T A C C T T G G T A C C T A G G T A G C T A G C A A C G T T G G T A G C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G T A G G A A G C T A G G T A C C T A G G A T G C T T G C T A G G A A G G T A G C T T G G T A G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A C C T A C C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T G C A T C C A A G C A A C C T T C C T T G C T T C C A T C C A A C G A A C C T T G G T A G C A T G G T A G C A A G C A A G G T A G C A A C C A A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G C T A G C A T C C A A G C A T C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A G G A A G G A A C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C T T C G A T C G A A G G T A C C T A G C T T C C T T G G A A C C A T G C A A G G T T G C A T G G T A G G A A G C A A G C A T G G A A G C T A G C T T C C T T C C T A C G T T G C A A C G A T G G T T C G T T G G T T G C T A C G T A G C T A G G T T C G T T G G T A G C T T G C A A G C T A C C A A G G A A G C T A C C A T G G A T G C A A C C A A C G T A C G A T C C A T C C A A G C A T G C T A C C T A C G A A G G A T C G A A C G A A G G T T G C T A C G A T G C T T G G A A G C A A C C T A G C T A G C A T C G T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A C C A A G C A T C C T A G C T A C C A A C C T A G C A +277 A G C T A G G T T C G T A G C T A C C T T G C T A G G T T G G T A C C T A G G A T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A G C T A G G T A C C A A C C T T G G T T G G T T G G A A G C A T G C T A C C A A C G A A G C A T C C T T C G A T G C A A G C T T C C T T G C T T G C A T G C A T C C T A G C A T G C A T G G T T C C T T C G A A G C T A C C A A G C T T G G T A G G A A G C A T C C T A G G T A G C T A G C T A C C A A C C T T G G A A C G T A C G T A G G A T C C T A G G T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G T T G C A A G G A A G G A A C C A T C C T T C C A A G G T T G G T A C G T A C C T A C G A T G C A A G C T A C C A T C G A A C G A T G C A T C G T A G G A A C G T A C G T A G G A A C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A A C G T A G G T A G C A T G G A A G C T A G G A A C G A A C C A T G G A A G G T A C C A T C G T A C C T A G G T A C C T T G C A T C G T A G C A T G G T A C C T T G G T A G C T T C G T A G G T A C C A A G C A T G G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A A G G T T G C T A G G A A G G T A G C A A C G A T C C A T C G T T G C T T G G A A C C A T G C T T G G A A G C T A G C T T G C A T G C A T C G T T C G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C A T G C T T C G A T C G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G G T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A C C A T G G A T C G T A G G A T G C T T G G A T C C T T C G T A G C T A C G T A G G T T G C T T G G T T G G A T G C A T G G T A G G A A G G A A C C A A C C T A G C T A G C T A C C T T C C T T G C A T G G T T G C A A C C T T G C T T G C T T C G T T C C T A G C A T G G T T C G T A G C A A G C T A G G T T G G A A C C T T G C A A C G A T G C A A G G T T G G A T G G T A G G A T G C T A C C T T C G T A G G A T G G T T C C T T G C A A G G T T C C T A G C A A G G T T C G A T G C A A G C T T C C A T G G T A G G T T G G A A C C T T G C T A G C A A G C T T G C A A G C A A C G A A C C T A C C T A C C A A C C T A C C T A C G A T C G A A G G A T C C A T G C T A C C T A C G A A G C T T C C T A C G A A G C T T G C T A G C A A G C A T G G T A G C T T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A A C C A A C C T A G C T A G G T A G C A A C G T +278 A G G T A C C T A C G A T G C T A C G T A C G A A G C T A C G T A C G A A G G T T C C T T G C A A G G T T C G A T C G T A G G T A G C T A C C T T C C A A C C T T G C T A G C A T C G A T G G T T C C T T G C T A C C A T C G T A C G T A G G T A G C A T C C T T C G T T G C A A C C T A C G A A G G T T G C T A C C A T C C T A G C T T C C A T G G T T C C T A C G A A G C T A C C A T G G T T C G T A C G T A G C A A C G A A G G T A G C T A G C T A C C A A C G A T G C T A G C T T G C T A G G T T G G T A C C A T G G T T G C T A C C T A G C T T C G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A C G T A C G T A C G T A C C T A C G T T G G A A G C A T C C A A C G A A C G A T C C A A C C A A C C T T C C A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C A T C G A A G G T A G C A T C C T A G G T A G G A T G G A A G G T A G G A A G C A A G G A T C G A T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G G A A G G T A C C A A G C T A G G T T C G A T G C T A C C A A G G T T C C T A C G T A G G A A G C T T C G T T G C A T G G A T C C T T G C T A G G T A C G T A C G A T G G T A C C A T G G T A G C A T C C T T G G A T G G T A G G A A C G T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C C A T C C A A C G A A C G T T G G A A G C A T C G A A G C A A C C A T G G T T C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T A G G A T G G T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T A C C T T G G A A G G T T G C A A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G A A C C T T C G A T C C T A C C A A G C T T G C T T G C A T G G T T G C T A C C A T C C T T C G T A G C A A G C T A G C T A G C T T C G A T G C T A C G A T G C A A G G T T G G A T G C T T G C A A C C A T C G A T C G T T C G T T C G T T C C T T C C T A C G T T C G A A G G T T G G A A G C T A G C A A G C T A C C T A G G A A G G T T G G A A C C T T G C T A G C A A G C T T G C A A G C A A C G A A C C T T C G T A C C T A G C A T C C T A C C A T G G A A G G A A G C T T G G A T G C T A G C A T G C T A C G A A C G A A G G T A C C A A G C T T G C T T G G A T G C A T C G T T G C A A C C T A G C T A G C A T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A C C A A G C A T G C T A G G T A G G A A G G T A C C T +279 A G G T T G G A T G C T T C C T A C C T T C G A A G G T A C G A A C G T A G G T T G C T T C C T T G G T T G G A A G C T T G G T A G C A T G C A A G C T T G C T A G G T A G C A T C C A T G G A A G C T T G C T T C C T T G C T A C C A A C G T A C G A T G C T T C G T T G C A A G C T T C G A T G G T A G G T T G C A T C C T A G C T T C C A T G C A T C C A T G G T A G C T A G C T A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A C G A T G C T T G C A A C C T A G C A T C C A A C G A A G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A C G T T G G T A G C A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G T T C C A A G G T A G G T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A G G T A C G T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G C A A G C A A C G A A G G A A G G T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A T G C A T C G A T C C T T G G A A G C A T G G T A G G T A C C A A C G T A C G A A C G T A G G T A C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G C T A G G T A G C A A G C A A G C T A G G A A C G A A G C T A C C T T G C T T G C A T C C T A C G T A G G T T G C A A G G A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C C T A G G A A C G T A G G T A C C T T C C A T G C A T C G T A G G A A C G A T G C A T C C T T C C T A G C T A C G T A G G T T G C T T G G T T G G T T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A A C G A A G G T A G C T A C C T T G C A T G C A A C C A T G C A A G G T A G C A T G G T A G G A T G G A T G G A T C G T A C G A A C G T T C C T T C C T A G G T A C C T A C C T A G C T T C G T T G G A A G C T T C C T A G C T A C G T T C C T A G C T A G C T T G G T A G C T A G G A A G G A T C C T T C C A T C G A A C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T A G C T A G G T T G C A A G C T T G G T T G C T A G G A A C G T A G C T T C C A A G C A A C C T A G G T A G C T A C G T A C G T +280 A G C T A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C C A A G G A T G C T T G C T A G G A A G G A A G C T A G G T A G C A T G C T T G C T T G C T T G G T T G C A T C G A T G G T A C G T T G C T A G C A T C G T A C C T A G G A T G G A T G C A A C G T T G C A A C C T T C G A T G C T T G G T T G C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C A T C G T T C G T A G C T T G C T A C G A A G G T T G C T A G C T A G G A T G C T A G C A A G C T A G C T A G G A A C C T A G C A A G G A A G G T A C C T A G C A A C G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G T T C G T A G G T A C C A A G C A A G G A A C G T A C G A T C C A A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G T A G G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G A T G G A T C C A A C C A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T T C G T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A T C C T T C G A A G C T T G C T T G C T T G G T T G C T T C C T T G C T A G G T A C G T A G G A T G C T A G C A A G G A A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C T T C G A T C G A A G C T A C C T A C C T T G C A A G C A A C C A T G C A T G G T T G C A T G G T A G G A A C C T A C G T T G G A A G G A A G G T T C C T T G C A A C G T T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T A C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T T G C T T G C A A C C T T G C T T G G A A G C T T C C T A G C A A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T diff --git a/inst/bta12_cgu.thap b/inst/bta12_cgu.thap new file mode 100644 index 0000000..839bbcc --- /dev/null +++ b/inst/bta12_cgu.thap @@ -0,0 +1,1424 @@ +A A T A A A T A A A A A A A A T A A A A A A T A A A T T T A T A A A A A A T A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A T A T A A A T A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A T A T T T A A A A A A T T A T A A A A A A A A T A A A A A A T A A A T A A A T A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A T T A A T A A A A A A A T A A A A A A A A A T A A A A A A A A T A A A A T A A T T A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A T A A A A A A A T A A A A A A A A A +G G G C G C G G G C C C C C G G G G C C C C G G G G C G G G G C C G C C G G G G G G G C C C G G G C G G C G G G C C G C G G C C C C G G G C G C G G G C C G G G C C G G G G G C C C G C G G C C G C G G C G C G C G C C C G G G G C C G G G G G G G G C G C G G G G G G G C G G G G C G G C G C C G C C C C G C G C G G G C G C C C G C G G G C G C C C C C G C G G C C G C G G C C G G C G C C G G C C G C G C G C G G G C G C G C C C G G G G G G G G C G G C G G G G G G G C G C G G G G C G G C G G G G G G C G C C C C G G C G G C C C G C G C G C G C G G C C G C G G G G +G G C C C C C G C C C C C C G C C G G C G C C G C C C G C C G C G C G C G C G G C G G C C C C C G C C C C G G G C C G C C G C C C C C G G C C C C G C C C C C G G G C C C C G G C C C C C C C C G C G G G G C G G G G C C C G G G C G C C C C C C C G G G C G C C G C G C C C G C G C C G C C C C C C C C C G C C C C G G C C C C C C C G G G C C C C C C G C C C C C C G C C C C C G G C C C C C C G G G C C C G C G C G C C C C C C C C G G G G G 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A T A A A A A A A A A T A T A A A A A A A A A A A A A T A T T A A A A A A A A A A A A A A A A T A A A A A A A T A T A T T T T A A A A T T A A A A T A T A T A A A A A A A A A T A T A T A A A A A T A A A A A A A A A A A A A A A A A A A T A A A T A +G C C G C C G C G G G C C G C C G G C G G G C C C C G G C G G G C G G G G C G G G G C G G C C G C C C C G C C G G C C G G C G C C C G C C G C G G C C G G C C C C G G G C G C G G G G G C C G G G G C C C G G G C C C G G C C C G C G G G G C C C G G G G G G G C C C G C G G G G G G G G G G G G G G G C G G G G G G C C C G C G C C G G C C G G G G G G G G G C G G C C G G C G C G G G G C G G G C C C C G G G C C C G G C C C G G C G C G C G G G G G G G G G G G C C C G G G G G G C G C G C G C G G G G G G C G C G C G G G G C G C C G C G G C C G G C G C G G G G C G G +G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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A T A T A T T A A T A A T A A A A T A A A T A A A T A A A A A T A A A A T T A A A A A A A A A T A A A A T T A T A T A A A T T A A A T T T A A A A T A A A T A A T T T A A A T T A A A T T A A A T A A T T T T T T T A T A T T T A A A T T A A T A A A T A T A A A A A A A T T T T A T T T A A T A A T T A T A T T T T A T T A A A A A T A T A A A T A A A A A T A T A T A T T T T A T T T T T T A A A T A T A T T A T A T A A A T T A T T T A A A T A T T A T A A A A T A T A A A T A A A A A T T T A T A +G C C C C C G C G G C C C C C C C G C C C C C C C C G G C G G C C C C C G C G C G G C C C C C C C C C C G C C C C C C C C C C C C C G C C C C C G C C C C C C C C C G C C C C C G C G C G C C C G G C C C G C G C C C C C C C C G C C C C C C C C G G C C C G C C C C G C C C G G G G G G C G C C G G C C C G C C C C C C C G C C C C C C C C C G C G C C C G G C C C C C G G C G C G G C C C C G C C C C C G C G C C C G C C C C C C C G C G C G G G G C C C G G C G C C C G C G C G G C G C G C C C G G C G G G C C C C C G G C G C C C C G C G C C C G C C C C C G G C C G C +C G G C G C C G C C C G C G C C G C G C G G C C C C G C G C C G C G G G C G C G C C G G C C C G C C C C C G G G C C G G C C G G C C C G C G G G C G C G G C C C G G C G C G C G G G C G C C G G C C C C G C C C G C G G G C G G C C G G G G G G G G C G G G C G G C G C C G G C C C G C C G C G G C C G G G C C G G G C G C C C G C C G G C C G C G C G G C C C G G C G C G C C C C C C C G G C C G G G C C C G C C C C C G G C G G C C C G C C C C C C G C C C C C C G C G C G C G C C G C G C C G G C C G C C C C G C C C C C G C G G C C C G C G G C C G C G G G C C G G C G +T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A A T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T +T A T A T T A T T T T T T T A T A A T A T T A T T T T T T T T T T T T T T T A T T T T T A T T A T T A T T T T T A T T T A A A T T T T A T A T A T A A T T T A T A T T T A T T A T T T T A T T T A T T T A A T A A T A T A A A A T A T A T A T T T T T T T T T T A T T T T T A A T A T T T T T T A A A T T T T A T T A T A T T T T T A T T A T T T T T A T T T T T T T T T T T A T T T T A A T T A T A T A T T T A A A T T T T A T T A T T A T A T A T T T T T T A A T T T T T T T T T A A T T A T T A A A T T A T A T A A T T T T A T T A T A T A T T T T T A T T T T T A T T T +C G G G G C G G C G G G G G G C G G G G G G G C G C C C G C C G G G G G C G G G C C G G G G C G C G G C C G G G G C G G G G G G G G C G C G G G C G G G G C G G G G C G G G C G C G C G G C G G G C C G G G G G G G G G G G G G C G G G C G G G G C C G G G G C G G G C C 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T T A T T T A T A T T T A T T A T T T T T T T T A A T A A A T A A A A T T T T T T A T T T T T T T T T T T T T T T T T T A T T A T A T T T T T T T T A T T T T T T T T T T T T T A T A T T T T T T A A T T T T A T T A T T T T A T T T T T T T T T T A T T A A T A T A T T T T T T T T T T T T A T T T T T T T A T T A T A T T T T T T A T T T A T T T A T T T A T T T T T T T T T A T T T T A T T T T T T T A T T T T T T T T T +A A A A A A A A A A A A A A T A A T A A A A T A A A A A A A A A T A A A A A T A A A A A A A A A A A T A A A A A A A A A A T A A A A A T A A A A A A T A A A T A A A A A T A A T A A A A A A A A T T T T A A A T A T A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A T A A A A A A A A T A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T T A T A T A A A A A A A A A A A A T A A A A A A A T A A T A T A A A A A A T A A A T A A A T A A A T A A A A A A A A A T A A A A T A A A A A A A T A A A A A A A A A +C C C C C C C C C G G C G G G C C G C C G G G C C C C C C C C G G G G G C C G G C C C G C G G C C G G C C C C G C C C G C G G C G G C G C G C C C C G G G C G C G G C C G C C G C G C G C C G G G G G G C G C G G G G G C C C C C G G C C C C C C C C G G G C C C C C C C G C G C G C C C G C G C C G G C G C C G G C C C C C C C C G G G C C G C C C C G C C C G G C G C C C G C G C C C C C C C C G C C G G G G C G C C C C C C C C G C C C G C C C C C C G G C C G C G C C C C C C G C C C G C G C G C C C G C C G C C C C C C G C G C C G C C G C C C G G G C G C C C C C G +C C C C C C C C C C G C G C C C C C G C C C G C C G C C C C C C C C C C C C C C C C G C C G G C C G G C C G G C C C G C C G C G G G C G C C C C C G G C C C G C G C C C G C C G C C C C C C C C C C C C G G C C G C G C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C G C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C G G C C G C C C G G C C C C C C C C C C C G C C C C C C C G C C G G C G C 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A T A T T T A T A T T A T A T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T A A T T T T T T T A T A A T T T A A T T T A T T T A T T A A A T T T T T T T T A T T T T A T T A A T T T A T T T T T T A T A +C G C G G G C G C G G G G G G G G G G C C C C C C G G C G G C G G G C G C G G C C G G G G G G G G G G C C C C C G C C G C G G C G G G G G G G G G G C C G C C C C C G G C C C C C C G G C C G G G G G G G G G G G G C C G G C C C G G G C G G G G G C G G G G C G G G C G G G G C G G C G C C G C G G G G G G G G G G G G C G G G C C G C G G G G G G G G C C C G G G G C G C G C G G G G G G G C C C G G G G G G G G G C C G G C C C G C G G G C G G G G G C G G C G C G C G G C C G G C C G G C C G G G G G G G G G G G G C C G G C G G C G G C G C C C C C G G G G C G C C G +G C C C C G G C G C C C C C C C C C C C G C G G G G C C G C C C C C G C G C C G G C C C C C C C G C C G G C C C C G C C G C C G C C G C G C C C G C G C C G G G C G G C G C G C C C C C G G C C C G C C C C C C C C C C C G G G C C C C G C C C C C G C C C C G C C C G C C C C G C C G G G G C G C C C C C C C C C C G C C C C C G G C G C C C C C C C C G C G C C C C G C G C G C C C C C C C G C C C C C C C C C C C G G C C G G G C G G C C G C C C C C G C C G C G C G C G G G C C G G C C G C G C C C C C C C C C C C G G G C G C C G C C G C G G G C G C C C G G C G G C +A A A T T T A T A T T T T T T T A T T A A T A A A A A A T T A T T T A T A T T A A T A T T T T T T T T A A T T T T A T T A T A A T T A T A T T A A T A T T A A A T A T T A T A T A T T T A A T T T T T T T T T T T T T T A A A A A T T A A A T T T A A T T T T A T T T A T T A T A T A A A A A T A T T T T T T T T T T A T A T T T A A T A T T T T T T A T A A A T T T T A A A T A T T T T A T T A T T T T T T T T T T T A T T T T A A T A A T T A T T T T T A T T A T T T T T T A T T T A A T T A T A T T T T T T T T T T T A A T T A T T A T T A T T A A T A T T T T A T A A T +A A A A A A A A A A A A A A T A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A A A A 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G G G G G G G G G G G G +G G G G G G G G G C G G G G G G G G G G G C C G C G G G G G G G G C G G G G C G G G G G G G C G G G C G G G G C G G G G G G G G G G G G C C G G G G C G G G C C G G G C G G G G G C G C G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G C C G G G G G G C C G G G G G G G G G G G G G C G C G G G G G G G G G C G G G G G G G C G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C C G G G G G C G C G G G G G G G G G G G C G G G C G G G G C G G G G G G G G G G G G G G G G G G C G G C C G G G C G G +T T A A T A A T A T T T T T T T T T T A T T T T T A A A T A A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T A T T T T T T T T T A T T T T A T T A T T A T T T T T A A A T T T A T T T T A T A T T T A T T T T T T T T T T A T A T T T A T T T A A T T T A T T T A T T T T T T T T A T T T T T T T A T T T T T T A T T A T T T T A T A T T T T T T T A T T T T T T A 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T T A T T T T T T T T T T T T A T T T T T A T T T T T A T T T A T T T T T T T T A T T T T T T T A T T T T T T T T T A T T T A A T T T T T A T A T T T T T T A T T A T T T T A T A T T T T T A T T T A T T T T T T T T T T T A T T T T T T A A T T T T T T A T T T T A T T A A T T A T T T T T T T T T T T T T A T A T A A T T T T T T T T A T T T A T T T T T T T T T T T T T T A T T T T T T T T A T +T A A T A A A A A A T A T A T T T A A A A A T A T A A A A A A A T A A A A A T A A A A A T T A A A A A A A A A A A A A A A A A T T T A A A A T A A A T A A A A T A A A A T A A A A A A A A A A A A A T T A T A A T T A A T A A A A A A A A A A A A A A A A A T A A A A A A A T T A T A A A T A A A A A T A A A A A A T A A A A A A A A A A A A A A A A T A A A A A T A T A A A T A A A A T T A A A A A T A T A A A A A A A A A A A A A A A A T A A A T T A A A A A A A T T T T A A A T A A A T A A A A A A A T A T A A A A A A A A A T A A A A A A A A T A A T A A A A A A A A A +C C C C C C C C C C C G C C C C C C G C G C C G 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G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +A A T A T T T T T T A T A T A A A T T A T T T T A A T A A T T T A T T T T A A T A T T T T T T T T A T T T T T T T T T T T T T T A A T T T T A T T A A T A T T A T A T T A T T A T T T T T T T T T T A A A A T T A A A A A T T T T T T A A T A A A A T T T T A T A A A T T A T A A A A T T A T T T A T T A T T T A T T T A T A T T T T T A T T A T T T A T T A T T A T T A T A A T T T T T T T T T T T A T A A A A T T T T T T T A T T T T A A T T T T T T T T A T T A T A T A T T T A T T A T T T A A T T T A T A T A T T T T A T T A T T T T T T T T T A A A A T T A T A T T A +T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T A T T A T T T T A T T T T T A T T T T T T T T T A T T A T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T A T T T T T T T T A A T T T T T T T T T T T T T T A T T T T A T T T T T T T A T T A A T T T T T T T T T T T T T T T A T T T A T A T A T T T A T T A T T T T T T A T T T T A T T T T T T T T T T T T T T T T T +C G G C G C C C G G C C C G G G C G G G C C G G G G G G G G G G C G G G G G C G G G G G G C G G G C G C G G G C C G C G G G G G C C G G G G C G G C G C G G G G G C G G G G G G G G G C G G G G G G G C G C G G C C G C C G C C G C G G C G G G G G C G G G G G G G G G G G C G C G G G C G G G G C G C C G G G G G G G G G G C G G C G G G G C G G G C C G G G G G G C G G G G G G G G G G G G C C G G G C C G C G G G G G G G C G G G G C G G G G G G G G G C G G C C C C G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G C G C G G C G G G C C G C G G +C G C C C C C C C C C C C C G G C C G C C C C C C C C C C C C C C G C C G C C C C G C G G C C C C C C C C C C C C C C C G C G G C C C C G C C C C C G C C C C C C C C C G C C G C G C C G C C C G G C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C C C C C G C C C G G C C C C C C C C C C C C G C C G C C C C G C C C G G C C C C C C G G C C C C C C C G G C G C C C C C C C C C C C C G C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C G C G C C C G C G C G C C C G C C C C C C C C C G C C C C G C C C C C C C C C C G C C C C C C +T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T A T A A T T T T A T T T T T A T T T T T T T T T A T T A T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T A T T T T T T T T A A T T T T T T T T T T T T T T A T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T A T T T A T T T A T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T +T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T A T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T A T T T A T T T A T T T T T T T T T A T T T T A T T T T T T T T T T A T A T T T T +G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G G G C G G G G G G G C G G G G G G G C G G G G G G G C G G G G G G G C G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C C G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G C G C C G G G G G C C G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G +C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T T T T A T T T T T T T T T T T A T T T A T T A T T T T T T T T A T T A T A T T A T T A T T A T T T A T T T T T T A T T T T T T T T T T T T T A A A A T T T T T T T T A T T A T A T A T T T T T T T T T T T A T T T T T A T T T A T T A T T T T T A T T T T T T T T A T T A T A T T T A A T T A T T T A T T T T T T T T A A A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T A T T A A T T T A T T T T T T T A T T T T T T T A T T T A T T T T T T T A T T T A T T T A T T T A T T T T T T T T T A T T T T A T T T T A T A A T T A T A T A T T +T T T T T T T T T T A T A A A A A A T A T A T T A T T A A A A A T T T T A A T T T A T A T T T T T T T T T T T T T T A A A T T A A A A A A T T T A T A A T T T T T A A A A T T A T A T A T T T T A A T A A T T A T T A T T A T T T A T A T A A A A T A T T T A T A A A A T T A T A T T T T T T A A T T A T T T T T T T T T A A T T T T A A A T T T T T A T A T T T A T T A T T A T T A A T A T T T T A A A T T A A A A T A T T A A T T A A A A A A T A A T T T A T T A A T A A T T T A A A T A A T A A A A T A A A A A A A T A A T A T T A A A T T T A A T A T T A A T A T A T A +G G G G G G G G G G C G C C C C C G G G G G G G C G G G C G G C G G G G C C G G G C G C G G G G G G G G G G G G G G G C C G G C C C C C C G G G C G C G G G G G G C G G C G G G G C G C G G G G G G G C C G G C G G C G G G G G G G G G G G C C C G C G G G C G C C C C G G G G G G G G G G G C C G G C G G G G G G G G G C C G G G G C G C G G G G G C G C G G G C G G G G G C G G C C G C G G G G C C G G G C C G C G G G G C C G G G G C C C G G C C G G G C G G C C G C C G G G C C G G C C G G C C G G C C C G G G G G G G G C G G G C C G G G G C G C G G C C G C G G G G +C G G G G G G G G G C G C G G G C G G G G G G G C G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C C G G G G C G G C G G G G G G G G G G G G C G C G G G G G G G G C C G G C G G C C G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G C G G C G G G G G G G C G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +A A A A A A T A T T T T T A T T T T T A A T T A T A T T A T T A A A A T A A A T A A A A A A T A T A A A A A T A T A A A T A T T T T T A T T A T A T A A A A T A A T T T A T A A T A A A T A A A T T A A T A A A A A T A T A T T T T T A A A A A A T A T T T T T A A A A A T A A A A A T A A A A A A A A A A T A A T A A T A T A T A A A A A T T A T T T T A A A A A T A T A A T A A T T T A A T A A A A A A T A T A A T T T T A T T T A T T T A T T T T A A T T T T T T A T T T T T T A T A A A T A T A T T T A T A T A A A A T T A A T A T A T A A T T A A A A A A A A A T T A +T A A A A A T T T T T T T A T T T T T A A T T A T A T T A T T A T A A T T A T T A T A A A A T A T T A A A A T A T A A A T A T T T T T T T T T T T T T A A A T A A T T T T T A A T A A A T A A A T T T T T T A A T T T A T T T T T T T A A A A A A T A T T T T T T A A T A T T A A A A T T T A A T A A A A A T A T T T A T T T A T A A A A T T T A T T T T A A A A A T A T A A T A A T T T A A T A T A T A T T T T A T T T T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T A T A T A T T T A T T T A T A T A A A A T T A A T A T A T T A T T A T T A A A A A A T T A +C C G G C G G G G C C C C G C C C C C C C C C G C C C C G C C G C C G C C C C G C C G G C C C C C G C C G G C G C G C G C G C G C C C C G C C C C G G C G G C C C C C G G G C G G G C C C G C C C G C C C C C C C C C C C C C C C C C G C G C C G C G C C G C C C C C C G G G G G G G C C G G G C C G G C G C C G G G G C G C C C C C G G C G C C C C C C G C G G C C C C G C C G C C C G G C C C G C C G C C G C G C C C C C G C C G G C C C C C C C C C G C G C C C C C C C C C C C C C G C C G G C C C C C C C G G G G C G C C C C C G C C C G G C C G G C C G G C G G C G G +G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G +A A A A A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A T T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A T A A A A A A A A A +T A T A A A A T A T T A T A A A T A T A T T T A T A T T T T T A T A A T T T A A T T A A T A T A A T A T A A T A T A A A T A T T T T T A T T A T T A T T A A T T A T T T T T T A A A A A T A A A A A T A T T A A T T T A T T T T T A T A A A T T A T A T T T T T T T T T A T A A A T A T A A A A T A A A A A T A T A A A T T A A T T T A A T A T T T T T A A T A A A T T T A A T T T A A A A A A A T A T A T A T T A T A A A T T T A T A A T T T A T A A T A A T T T A A T A T A A T T A T A T A A T T A T T T A T A A A A A A A A A A T A T T A T A A T T T A A A A A A A T A A +C G G C C G C G G G C G C C G C C G G G C C G C G C G G G G G C C C C G G G C G G G C C G C G C C G C C C G C C C G G C G G G G C C C G G G C C G G C C C C C G C C G G C C G G G C C G G C C C C G C G G C G C C C C C C C C C C G G G C G G G G G C G G G C C G G G G G G G C G G C G C C C C G C G G C C G C G G G C G C C G C C C C G G C G C G C C G C G C C C G C C C G G C G C C G C C C G G C C G C C G C G G C C C G G C C G G C C C G C G G G C C C C G C C C C C C C C C C C C G C C G G C C G G C C C G G G G C G C C C G C G G C C G C G G G G C G G C C C C C G G +G G C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C G C G C C C C C C C C G G C C C C C C C C C C C C C C G C G G C G G G C C G G C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C G G C C C C C C C C C C C C G C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C G G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C G C C G C G G C C G C C G C C C C C C G C C C C C G C C C G C C G C C C C C C G C C +T T T T A T T T T A T A T A T T T T A T T A T T T T T T T T T A T T T A A T T T A A T A T T T T T T T T T A T T T T T A T T A T T T A A T A T T A T T A T T T T T T T T T A T T T A T T T T A A T T T T T T T T T T T T T T A T T T A T T T T T T A A A A T T A T T T A A T T T T T T T T T T A A T A A T T A T A T T A T T T T A T T A A T T A T T T T A A T T T T T T A T T T T A T T T A T T T T T T T T T A T T A T T T A A T T A T T T T A T A T T T T T A A A T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T A T T T T A T T T T T T A T A T T T T +T T T A A T A A T T A A A A A T A T T A A A A A A A A A T T A A T T A A A A T T T A A A T T A A T A A A A A T A A T T A T A T T A A A A T A A T T A A A A A A A A A A T A A A T T A A A A A A A A T T A T T A T T T T A A A T T A A A T T T A A A A T A A T A T A A A A A T T T T T T A T T T A A A A A T A T A A T T A T A A A A T A A A T A T A T T A A A A T A T T T A T A T T A T T T T A A T A A T T T T T A T A T A A A A A A T T A A A A A T T T A A T T T T T T T T A A A T A T T T T T A T A T T A A T A T T T T A T A A T A A T T A T A A A T T T T A T T A T A A T A +G G G G C G G G G G G C C G C G C G G G G C G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G C G G G G G G G G G G C C C C G G G G G G G C G G G G G C G G C G C G G G G C G G C C C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G C G G C C G G G G G G G G G G G C G C C G G G G G G G C G C G G C G G G C G G G G G G C G G G G G G G G C G G G G C G G G G G G G G G G G G G G C G C G G G C G C G G G G C C C G G G G C G G G G G G G G G C G G G C G G G G G G G C G G G C G C G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G +G G G G C G G G G G G C C G C G C G G G G C G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G C G G G G G G G G G G C C C C G G G G G G G C G G G G G C G G C G C G G G G C G G C C C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G C G G C C G G G G G G G G G G G C G C C G G G G G G G C G C G G C G G G C G G G G G G C G G G G G G G G C G G G G C G G G G G G G G G G G G G G C G C G G G C G C G G G G C C C G G G G C G G G G G G G G G C G G G C G G G G G G G C G G G C G C G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G +T T T T T T T T T T T A A T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A A A T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T T T +A A T A A A A A A A A T T A T A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T T T A A A A A A A A A A A A A T A T A A A A A A A A A A A A T A A A T A A A A A A A T A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A A T A A A A T T A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A A A A +G G G G C G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G G G G C G C G C G C G G G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G C C G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G C G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G C C G C G G C G C C G G G G G G C C G G G C G C C C C C G G G C C G C G G G C G G G G G C G C G G G G G G G C C C C C G C G G G G C G G G G G G G G G G G G G G G G G G G +C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +A A A A T T A T A A T T T A A A T A A A A T A T T T A A A T A A T T A A A A T T A A A A T T A A A A A A A A A A A A A A T A A T T T T A A A A T A A A T A A T T A T A T A A T T T A A A A A T T A A T A T T T A T T A A A A A A A A A T T T A A A A A A A T T A A A A A A T T A A T A A A T A A A T T T T A A A A A A T A A T A A A A A T T A A A A A T A A T A A A A T A A A A A T A A A A A A T A A T T T A A T T A A A T A A T T A T A T T A A A A A T A A A A A A A A T T T A T T A A A A T T A T A A A T A T T A T T A A A T A T T T A T A A T A A A A T T A A A T A T A A +T T A T A T T T A T A A A T T T A T T T A A T A A A T T T A T T A T T A T T A A T T T T T A T A T T A T T T T T T T T T A T T A A A A T T T T A T T A A A T A A T A T A T T A A A T T T T T A A A T T T T A A T A T T T A T T T T T T A T T T T T T T A A A A T T T T T T A T T T A T A A A A T T A A A A T T T T T T A T A A A T T T T A A T T T T T A T T A A T A T A T T A T T A T T A T T T T T T A A A T T A A T T T A T T A A T A T A A T T T T T T T T T T T T T T A A A T A A T T T T A A T A T T T A T A A T A A T T T A T T A A T A T T A T A A T T A T T T A T A T T +C G C G C C C G C G C C C C C G C G C C C C G C C C C G C C C C C C G G C C C C C C C C C C C C C G C G C G C C G C G C C G G C C C C C C C G C C G C C C G C C G C G C G C C C C G C C G G C C G G C G G C C G C G C G C C C C G C G G G C C C G C G G G C C G C C C C C C C G G C G G C C G C C C C C C G G G G C C C C C C C C G G C C C G C G C C C G C C C G G C C G G G C G C G G C G G G G G G C C C C C C C C G G C C C C C C C G C C C G G G G C G C C C G C C C C C C C C C G C G G C C G C G G G C G C C G C C G G G C G C C C G C G G C G C C C C C G G G C G C G G +C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C G C C C G C C C C G C C G C C C C G C C C C C C G C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C G C C C C C C C G G C C C C C C G C C C G G C C C G C C C C C C C G G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C G C C C G G C C C C G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G G C C C C C C C C C C C G C C C G C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C +T T A A T A A T T T T T T A A A T T T T T T T T T T A T T T T A T A T A A T T T A A A A A T A T A T T T A T A A T T T A T A T T T T T A T A T T T T T T T A T T T T T T T A T T T A A A T T T T A T A T T T T A T T A T T A A A A T A A A A T T T T A A A T T A A T T A A T T A A T A A T T A A A T T T A A T T T A T T T T T T A A T A T T T A T A A T T A T T A A A T A T A A A T A A T T T T A A T T T T T T T T A A A T A A T T A T A T T A T A T T T A T A A T T T T T T T A T T A A T A T T T T A T T T A T T T T T T A T T A A T T T T A A T A T T A A T A T A T A T A T +T T T T T T A T T T T T T T T T T T T T T T T T T T A T T A T T T T T T A T T T T A T T T T T T T T T T A T A T T T T T T A T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T A A T T A T T A A T T A T A T T T T T T T T A A T T A T T A T T T T T T T T A A T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T A T T T A A T T A T T T T A T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T A T +C C G C G C C G G G G G G C G C G G G G C C C C C C G G C G G C G C G G C G G G C G C G C C C G C G G G G G C G G G C C G G G G G G C G G G G G C C C G G C C C C G C G G C C C G G G G C C G G C G C G G G G C G G C G G G G G G G C G C C G G G G G G G G G C G G G C C G G C C G C G G G C C C G G C G C C G G G G G C G G C G G G C C G G G G G G G C C G C C G C G C G G C G G C C G C G G C G C G G G C G G G G G G G G G G G G G G G G G G C G G G C G C C G C C C G G G G G G C G G C C G G G C C C G C G G G G G G G G G C C G G G G C C G G G G C C G G G G G C C G G +C C C C C C G C C C C G C C C C C C C C C G C C C C G C C C C C G C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C C C C C C G C G C G C C C G C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C G G C C C C G C C C C C C C C C C C C C C C C G C C C G G G G C C C C C C C G G C C C G C C C C C C C C C C C G C G C C C C G C C C C G C C C C C G C C C C G G C C C C C C C C C +A T A T T T T T A T T A A T T T T T A T T T T T T A T T T T T T T T A T T T T A A T T T T T T T T T T T T T T T T T T A T T A A A A T A A T T T T T T A T T T T T T T A T T T A T T T T A T A A T T T A T A A T T T T T T T T T T T T A A T T T T A T T T T A T T A T T T T A A A A T T T A T T T A T T T T T T T T T A T A T T T T T T T A T T A T T T T T A A T A T T T A A T T A T T A A T T T T T T T T T A T T A T T A T A A A T T T A A A T T T T T T T A T T A A A T A A A A A T T T T T A T T T T T A T A T T T T T T T A T A A T A A T T T T A A T A A T T T A T A T T +A A A A A A A T A A A A A T A A A A A T A A A A A A A A A A A T A A A A A A A A A A T A A T A A A T T A A T A A T T T A T A A A A A A A A A A A T A A A A A A A T A A A A A T A T A T A A T A A A A A A A A A A A A A T T T A A A T A A A A A A A A A A A T A A A A A A T A A A A A A A A A T A A A T T A A T A T A A A T A A T T A A T A A T A A T T T T A A A A A T T A A A A A A A A A A A A A T T T T A A A T T A A A A A A A A A T A A A A A T T T A A A A T A A A A A A A A A A A T A A T A A T A A T A A A T A T T A A T A A A A T A A A T T A A A A A A A T A A A A T T +C G C C C C G G C C G C C G C G C G C G C C G C C C C C G G C G C G C C C C G C C C G C C G C G C G G G C G C C G G G C G C C C C C C C C C G C G C C C G G C C G C G C G C G C G G G G C G C C C G C C G C C G G G C G G G G G C G C C C C C C C C G C C G C C C C C C G G C C C C C C C C G C C C G G G C G G G C C C G C G G G C G G G C G C C G G G G C C C G C G G C C C C C C G G C C G C G G G G G G C C G G C G G C C C C C C G G C C C G G G G G C C C G C C C C G C C C C C G G G G G C G G G G G C G C G G G G G G G C G C C G C C G G G G C C C C C G G G C G C G G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T T A T T A T T T T T T A T T A A T T T T T T T T T T T A T A T T T T T T T T T T A T T A T T T A T T T A T A T T A T A T T T T T A T T T A T A A T T T T T T A T A T A T T T T T A A T T T T T A T T T T T T T T T A T A T T T T T T T T T T T T T T T A T T T A T T T A A T T T T T A T T T T T T A T T T T T T A T A T T A T T A A T T T T T T T T A T T T T T T T T T T T T T A A T T A T T A A T T T T T T T T T A T T T T T T T A T T T T A A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T +T T T A T A T T T T T T A T T T T T T T T A T A T T T T A T T T A T T T A T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T A T A T T T A A T T T A T T T A T A A T T T A T T T T T T A T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T A T T T T T T A T A T A A T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T A T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +C C G G G G G G C C G C C G G C G G C C G C G C G G G C C G C G G G C C G C G C C C G G G G C C G G C G G G G G G C G G G G C G G G G C C C G G G G C G G G C G G G C C G C G C G G G G C C G G C C G C G G G G G G C G G G G G C G G C G G C C C C G C G G C G C G G G G C G G G G C G C C G C G G G G G G G C G G G G G G G C G C G G G G C C C G G C G G G G G G G G C C C C C G G G G G G C G G G G G G G C C G C G G G G C G G C G G G C C G G C C C C C C G C C C C G C G C G C G G G G G G G C G G G C G C G G G G C G G G G G G G C G G G C C G G C C G C G G G G C G G +T T A A T T T T T T T T T T T T A T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T A T A T T T A A T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T A T A A T T T T T T T A T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T +A A T T A A T A A T T A A A A A T A A A T A A A T A A A A A A A A T A A A T A A A A A A A A A T A A T T A T A T T A A A T A A T T T T A A A A A A T A T T A A T T A A A T A A A A A A T A A T T A A T A T A A A T A A A A A T T A A A A A A T T T A T A T A A A T T T A T A T A A T A A A A A A A T T A T A T A A A T A T T T A A A A A T T A T A A A A A A T A T T A A A A A A A T A A A A A A A T A A T A A A A T A A A A T A T A A T A T A A T A A A A A T A T T A A A A A A A A A A T T A A A T A A T T A A A T A T T A T A A A A T T A T A T A A T T A A A A A T T A A A T +G G C C C G G G G C G G G G G G C G G G C G G G C G G G G C G G G G G G G C G G G G G G G G G G G G C G G G G C G G G G G G G G G G C G G G G G G C G C G G G C C G C G G G G G G G G G G C C C G G G G C G G G G G G G G G G G G G G G G G C C C G G G G G G G C C G G C C C G G C G G G G G G G G C G C G C G G G C G C C G G G G C G C C G C G G G G G G C G G G G G G G G G G G C C G G G G G G G C C C G G C C G G G G G G G G G C G G G G C G G G G G C G C C G G G C G G G G G G G G G C G G G C G C G G G C G C C G G G G G G G C G G G C G G C C G G G G C G G C G G G +C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T T T T T T T T T T T T A A T T T T A A A T T T A T T T A T A T A T T T T T T T T T A T A T T T T T T A T T T A A T T T T T T T A T T A A T T T T A T A T A T T T T T T T A T T A T A T T T T T T T T T T T A T T A A T T A T A T T T A T T T T T A A T T A T T T T T A A A T T T T T T A T T T T T T T T T T T A T T T A T A T T A T T A T A A T A T A T T T A A T T T +G C C C G G G G C C C C G C G G C G C G C G G C G G G C C C C C C G G C G C C G G G C C G G G C C C G C G C C C C G C G C G C G C C C C G G G C C G C C G G G C C G G C G C G C C G C G G C C C C C C G C C C C G C G C C C C C G C C G C C C C C C C G C C C C C C C G C G C C G C C G G C G C C C C G C G G C C C G G G C C C G G C C C C C C G C G C C C G G G C G G G C C G G G C C C C C C G G C C C C C C G C G G C G C G C G C C C C C G C G C C C G C C G C G C C C C G G G C C C C C C G C G C G G C C C C C C C C C C G C G C C G C C C G G G G G C G G C C G C C C C +C G C C C C C C G C G G C C C C C C G C C C C C C C C C G G C C C G C C C C C C C C C C C C C G C C C G C C C C G C C C C C G C G G C C C C C C G C C C G C C C C C C G C C C G C C C C C C C C G G C C C G C C G G C C C C G G C G C C C C C C C C G C G C G C C G C C G C C C C C G C C G C G C G C C G C C G C C C C C C G G C C G C C C G C C C C G G C C C G C C C C C G C C C C C C C C G C G C C C C C C C C C C C C C C G C G C C G G C C C C C G C C C C C C C C C G C C C G C G G C C C C C C C C G C G C C C C G G C C C C G C C G C C C C C C C C C C C G C C G C G +T A A A A T T A A T A A A A A T A A A T A T T T T A A A T T A A A A A T T T A T A T A A A A A A A A A A T A T T A T A A A A A A A A A A A A T A A A A A A T T T A T T A A A A A A T A A A A A A T A T A A A A T A A T A A A A A A A T T T A T T T T A T A A A A T A A T A A A T T A A A A A T A A A T A A T A A A A T A T T A A A T A A A A A T A A A A A A A A A A A A T T A T T T A A A A A A T A A A T A A A A T A A T A A A A A A T T A A A T A A A A T T A A T A A A A A A A A A T A A T A T T A T A A A T A T T T T A A T A T A A T A A T T T A T A A A A A A A T T A A A +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G C G G C G G G G G G G C G G G G C G G G G G G C C G G G G G G G C G G G G C G G G G G G G G C G G G C G G G G G G G G G G G G G G G G C G G C G G G G C G C G G G G G G G G G G G C G G G G G G G C G G C G C C G G G G C C C G C G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G C G G G G G G C G C C G G G G G C C G G G G G G G G G C C G G G G G G G G G G G C G G G G C G C C C G G G C G G C C G C G C G C C G G G C G C C G G G G G G G G G C G C G C G G G C C G G G G G G G G G G C G C C G G C C G C G C G G G G G C G G C G C G G G G G G G G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T A A A T A A T T T T A T A A A A T T A A T T T T T A A A T A A T A A T A T T T T A A T T T A T T A T T A A T A T A A A T T A T A A A T T A A T A T T A T T T T A T T A T A A T T T T A T T A A T T T A T A T T A T A T A A T T A T A A A T T T T T A T T T T T T T T A A T A A A T T A T T T T T T T T A T T T A A A T A A T T T A A A A A A T T A T T T A T A A T T T A T T A A T T T T A A T A A A T T A A A T T A T A T T T T T T T A A T T A T A A T T T A T T A T A A T T A T T T T T A T T T T T T T T T T T T T T T T A T T T A T T A T T A T T T T T T T T T T T T A T +T A A A T A A T T T T A A A T T A A T A A A A T A A T T T T A T T A A T T T A T T T A T T T T T T A T T T T T A T T A T T T A T A A A T T T T T A T A A A T A A A T T T T A T T A T T A A T A A A T T T T A T T A T T T T A T T A T T T T T T T T A A T A T A T T T T T A T A T T T A T A T A T T T T T A T T A A A A A A A T T A T A A A A T T A T T A T A T A A T T A T A T T T A T T A T A T T T A T A A T A A A T T A A T T T A A A A A A T A T A A A A T T T T T T T A A A T A A T A T A T T T A T A T A T A A T A A A A A A T A A A T A T T T A T T A A A T T A T T T A A +C C C C G G C G C G C C C C C C G G G C C G G G G G C G C C C G C C G G C G G C C C C C C C G C G G G C C C G G C C C C C C C G C C C C G C C G G C G C G G G G C C C C C C C C C C C G G C C C C C G G G G C G G C C G G G C C G C G C C C G G G G C G G C C C G C C C G G C C C G C C G C C C C C G G G C C G C G C G C G C G G C C C G C C G G C C G C C G G G C C G C G C C C G C C G C C G C C G C G G G C C G C C G G C C G G C G G C C C G G C C C C G G C G C G C G C G C G C G C C G G C G C G G G C G C G G G G C C G G G G C G G C G G C G G G G C G C G C C G C G C +G G G G C G G G G G G G G C C C G G G G C G C G G C C G C C C G G C G G G G C C G C C C G G G G G G G G C C G C G C C C G C G G G G G C G C C G G C G C C G G G G C G C C G C G G C C G G G G G G G G G G C G G G G C G G C G G G G G C C G G G G G G G G C G C G G G C G G G C C G G C C G G G C C G G G G G G C G G C G C G G C C G C G G C G G C G C C C G G C C C G C G C C C G G G C G G G C C G C G C G G C G C G G C G G C C G G G G G G G G G G G C G G C G G G G C G C C G G G G G G G G G C G G G G G G G G G G G G G C G C G G G G G G G G G G C C C C G G C G C C G +T T T A T T A T T T T A T T T T A A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T A T T T T T A T T T T T T T T T T T T A A T T T A A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A A T T T T T T T T T A T T T T T T A T T T T T T A T T T T A T T T T T T T T A A T T A T T T T A A A T A T T T T T T T T T T T T T T T T T T T T T A T A T T T A T T T T T T T T T T A T T T A T T A T T T A T T T T T T T A T T T T T +T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T A T T T A T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T +G G G G G G C G G G G C G G G G G C G G G G C G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G C G C G G G G G G G G G G G G C C G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G C C G G G C G G G G G G G G G G G G G C G C G G G G C G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G +C C C C C G C C C G C G C C C C C G G C C G G G G G C G C G C G G C C G C G G G G C C C C G C C C C C C G C G C C C C G C C G G G G C C G C C C G G G C C G G G C C C C C G C G C C C G G C G G C G G C G C G G G G G C C C C C G C G G G G G G G G G G C C G C G C C C C G G G G G G C G C G G G C G G G C C G C C G G G G C C G C G C C C C G G C G C C 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T A A A A A A T A +T T T T T T A T T T T A T T T T T A T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T A T A T T T T T T T A T A T T A A T T T A T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T A T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T +C G G C C G C C G C C C G C C C C C C G G G G C C G C G C C C G C G G C G C G G C G C C G C G C G C C C C G G G C G C C C G C C C C C G C C G G C G G G C G G C C G C C C C G C C C G C G C C C C C C C C C G G C C C C G G G G C G C G C C C C C C G G G G C G C C G G C C C C G C C C G C C C C G C C C C C G G C C G C C C C C C G C G G G G C C C C C C C G C C C G C C C C C C G G C C G G C G C G C C C G G C G C C C C C C G 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A A T T T T T T A T T T T T A T T T T T T T A T T T T A T A T T T T T T T T T T T T T T T T T T A A T T T T T T T T A T T T T T T T T T A T T T T A T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A A A A A A A A A A T A A A A T A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A A A A A A T A A A A A A A T A T A T T A A A A A A T A A A A A A A A A A T A T A A A T A T A A T T T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A T A A A A T A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A A T A A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A A A A A A A A A A A A T A T A T A A A A A A A A A A A T A T A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A A +C G G C C C G C C C C G C C C C G C C G C C G C C C C C C C C C C C G G G G C C C C G C C C G C C C G C G C C C C C C C C C G C G G C C C G C C C C G C C C G C C C G C C C G C 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T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G C G C G G C G G G C G G C G G G G C C G C G G G C G G G G G G G G G C G G G G G G G G G G G G G G C G G G G C G C G G G C C G G G G G G G G C G G C C G C G G G G G G G C G G G G C C C G G G G C C G G G G C G G G G G G G G G G G G G C G G G G G C G G G G G C G G C G G C G G G G G G C G C C G C G G G G G G G G G C G G C G G G C C C G G C C C C G G G C C C G G G C G G G C C G G G G G C G G G G G G G G G C C G G G G C G G G G G G G G G G C G C G G G G C G G G C C G G G G G G G G C G G G C G G G G C G G G G G G G C G G G G G G G G G G G C G G G G G C C G G +C C C C G G C G C C C C C G C C G C G C G C C C C G C G C C C G C C G C C C C C C G C C C C G C C C C C G G G C G G C C C G G C C C C G G C C C G C C C C C C C G G C C C C C C C G C G C C C C C G C G C C G G G C G G C C G G C C G C C G C C C C G C C G C C C C C C C C C C C G C C C C G C C G C C G C G C G C G C C C C G G C C C C C C G G C C G C C G C G C C C C G C G C G G G G C G C C G G G C G G G C C C C C G C C G C C G G C C C G C C C G G C G C C C C C G C C C G C G C G G G C C C G C C C G C C C C G C C G C C C G C G C G G C G G G C C G C C G C C C C C +T A A T A T T A T T A A A A A A A T A T A T T T T T A A T T A A A T A T T A T T A A A A A A A T A T T A A A A T A A A A A A A A A T T A A A A T A A T T A T T T A A T A A A T A T A T T T T A A A A T A A A A A A A A A T A A A A A A T T T A A A A A T T A A T A T T A T A A T T A A T T T A T T A A T A A A A A T T T T T A A A A 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C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +G G G G G G G G G G G G G G G G C G G G G C G G G G G C G G G C C C G G G C C G G G G G G C G C G G C G G G G G G G G G C G C G G C G G G G G C G G G G G G G G G C G G G C G G C G C C G G C C C C C G C G G G G G G G C G C C G G G G G G C C C G G G G G G G C C G G C G G G G G G G G G G G G G G G G C C G G G G G C G G G C C G G C C G G C C C C C G G G G G C C G C G G G C G G G G C C G C G C G G G G G G G G G G G G C G G C G G G G G G G C C G G G G G G G G G G G G G G G C G G C G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T T T T A T T A A T T A A T T A T T T A A A T T T T T A T T T A T A T T T A A A T T T T A A T T A T T T T A T T A A T T T T A A A T A T T A T T A A A A A T A T A T T T T T A A A A A A T T T A A T T T T T T T T A A T T T T T T A T T T T A T T A T A T T T A T T T T A A A A T A A A T T A A T A A T T T T A T T T T T A T A T A T T T T T T T T T T T A T T T T A A A A A A A A T A T T T T A T T T T A T T T A A A A T T A T T A T T T A T T T T T A T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T A A A T A A A A T T T +A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T A T T T T A T A T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T A T T T A T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G C C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G G G G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C G G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C 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A A A A A A A A A A A T A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +C C C G C G G C C G G G C G G G C G C G C C C G G G G G G G G G G G C G C C G G G G G G G G G C C C C C G G C C G G G G C G C G G C G C G G C C C C C G C G G G G C G C C C G C G G C G G C G G C G C G C C G G G C G G C C G G G G C G C G C C C G G G C C C C C C C C C C G G G G G G G G G G C C C G G C G C C G C C C G C G C C G G G G G C C C C G C G C G G C C G G C C G G C G G C C G C G C G G G G G G G C C G G G G C G G G G G G C G G C G G G G G G C G G C G G C G G C C G G G G G C C C G C C C G C G C G G G G G G G G G G G G G G G G C G G G G C G G G G C G C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T T T A A T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T A A T T A T T T A T T A T T T T T A T T A T T T T T T T T T A A T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A A T T T T T T T T A T T T T A T T T A A A T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T +C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T A A T T T T T T T A A A T T A T T T T T T T T T T A A T T A A T T T T T T A A T A T T T A T T A T T A T T A T T T A A T A A T A A T A A T A A A T A T T T A T T T T T T T A T T T T T T T T T A A A A T A A A +A A A T A A T A T T T T A A T A A A T A A T A T A A A T T A A T A T T A T A T A A T A T A T A A A A A A T A A A A A A T T T A T T T T A A T T A A A A A T T A A T T A T T A T T T T T A T T T T A A A A A A A A A A A T A T T T A T T A A T T A T T A T A A A A T A A A A T T A T T T T A T T A A T T T A A T A T T A A A T T A A T A A T A A A A A A A A A T A A T A A T T A A T A A A A T T A T A T T T T T A T T T A T T A A T T T T T T A A T A T A T T A T A T T T T T A T T A A A T T A T T A T A A A A A A T T T T T T T T T T T T T A T T T T A T T T T T A T A T A T T +G G G G C G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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C C G C C G C C C C C C C C C C C C +C C C C C C G G C C C C C C C C C C C C C C C C C C C C G C C C C C G C G G G C C C G C C C C C C C G C C C C C C C C C C C C C G C C G C C C C C G C C C C C C C C C G C C G C C G C G C G C C C G C G C G G C C G C C C C C C C C G C C C G C C G G C C C G C G G G G C C C C C C C C C G C C C C C C C C C C C C C C G C C C G G G C G C C C G C C C C C C C G C C C G C G C G C C C C C C C G C C C C C C C C G C C G C C C G C C C G C C C C C C G G C C C C C C G C G C G C G C G C C G C C C G G C C C G C C C C C C C C G G G C C C G G C C C C C C C G C C C G C C C C +A A A A A A A A T T T A A T T T A A T A T T A T T A A A A T A A T A A A A A A A T T A A A A T T T A A T T A A T T T A A A A T A A T A A T T T T A A A T T A T A A T T A A A A A A A A A A A A A A A A A T A A A A A A A A T A A A T A A A A A A A A A A T A A T A A A A T T A A A A T A A A A A A T T A A T A T A A A A A T T A A A A A A A T T A T T T T A A A A T T A A T A T A A A A T A A T A A A A T A A T A 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G G G G G C G G G G C G G G G G G G G C G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G C C C C G G G G G G G G C G G G G G C G C G G G G G G G G G G C C G G C G G G G G G G G G G G C G G G G G G G G G G G G G G C G C G G G G G C G G G C G C G G G G G G G G G C C G C +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G C G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G G G G C G G G G G C G C G C G G G G G G G G G G C C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +A A T A A A T T T A A A A T A A A A T A T T A T A A A A A A A A A A T T T A T A T T A A T A A T T A T A T A A A A A A A T T T A A A A T T T T A A A A T T A A 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C C G C G C G C C C C C C G C C C C C C C C C C C C C C C C G C G C C C G C C C C C +T T T T A A T T T T T T T T T T T T T T T A T A T T A T T T T T T T T A A T A T T T T T A T T T A T T T T T T T T T T T T A T T T T T T T A T T T T T A A T T T T A T T T T A T T A T T T T T T A A A T T A T T A T T T T T A A A T T A A T A A A A T A T A A T A T T A T T T T T T T T A A T T T T T T T T T A T T A T T T A T A T T A T T T A A T T T T A A A T T T T T T T T T T T T A T T T T A T T A A T A T A A T T A T A A T T T A T T A T A T T A T T A T A T A A T T A A T T T A T T T A A A T A T T T T T T A T T T T T A A T T T T A T T T T A T A T T T A T T T T T +A A A A A A A A A T A A T A A A A A A A A T A A A A A T T A A T A A A T A A A A A A A A A T A A T A A A A A A A A A A A A T A A A A A A A T A A A A A A A T A A A T A T A A A A A A T A A A A A A T A A A T A A T A A A A A A A A A A T A A A A A A A T A A T A A A A T A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A A A A T A A A A A A A A A A A A T T T A A A T T A A A A T A A A T A A A T A A T A A A A A A A A A A T A A A T A A A A A T A A A A A A A A A T A T A T A A A A A A A T A A A T A A A A A A A A T A A A A A +C C G C G C G C C G C C C C C C C C G C G G C G C C C C G C G C C C G G G C C C G C C G G C C G C C G C G C C C G C G G C G G C C G C G G G G C C C G G G C C C C G C G C C G C C C C C C G C C G G G C C G C C G G G C C C C C G C G G G G G G C G C G C C C C G C C C C G G C G C G G G C G C C C C C C G G C G C G G C C C G C C G C C C G C C C C C G G C C C G C C C G G C C C C C G C G C C C C C G C C C C C C G C C C G C C C G G C C G C C G G G G G C C C C G C G C C C G C C C C C C C C C C C C C C C C C C C G C C G G G G C C C G C C C G C C C G G G G C C C G C +G C G G C C C G C C C C G C G C C G C G C G C C C C G C C C C C C C C G C G C G C G C C C C C C G C C C C G G G G G C C G C C G C C G C C G C G G C C C C C C C G G C C G C C G C G C C C C G G C C C G G C G C G C C G G C G G C C C C G C C G G C G C C G G C C C G G C C C G C G C C C G C G G G G C G G C G C C C C G G G C G C C G G G C G G G G G C C G G G C C G C C G G C G G G C C C G G C G C G G C C C G G C C C G G C C G C C C C G C G C C C C C C G G G C G C C C G C C G G C G C G G C G C G C G C G G G G C C C C C C C C G G C G G C C G G C C C G C G C C C C +A A A A T A T A A T A A A T A A A T A A T A A T T T A A A A T A A A A A A A T A A A A T T A A T A T T A A A A A A A T T A A A A A A A T T A A A T A A T T A A T A A A T A A A A T A T A T T A A T A A T A T A A A A A T A T A A T A A A A A A A A A A A A T T A A A A T A A A A T A A T T T T A T A A A A A A A A A T T A A A A T A T A A A T A T A A A T A T A A T T A A A A A A A T T T A A A A T A A T A A A A A A T A A A T A A A A A A A T A A A A A A T A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A T A A A A A A A A A A A A A T T A T T A A A A A T A +T T A A A A A A T T T A A A A T T A T A A T A A A A A T T T A T A T T T A A A A A A T A A A T A A A A A T A A T A A A A T A A A T A A A A A A A A T A A A T A A A T T T A T T A A A T T A A A A A A T T T T A A T T T A A A A A A T A T A A A A A A A T T A A T A A A A A A T T A T T A A T A T A A A T A T T A T T A A A A T T A T A A A A A A A A A A A A A T A A A A T T A A T A T T A A T A A A A T A A T T A A T A T A T A A T A T A T T A T A A A A T A T A A A A A A T A A A T A A A A T T A A A A A T A T A A A A T A T A A A T T A A A A A T T A A T A A T T A A T A T +C C G G G G G G C C C G G G G C C C G G G C G G G G G C C C G C G C C C G G G G G G C G G G C G G G G G C G G G G G G G G G G G C G G G G G G G G C G G G C G G G C C C G G G G C G C G G G G G G G C C G C G G C C C G G G G G G C G C G G G G C G G C C G G C G G G G G G C G G C C G G C G G G G G C G C C G C G G G G G C C G C G G G G G G G G G G G G G C G G G G C C G G C G C C G G C G G G G C G G G G G G C G G G C G G C G C G G C G G G G G G C G G G G G G G G C G G G C G G G G C C G G G G G C G C G G G G C G G G G G C G G G G G G G C G G C G G C C G G G G C +G G G C C C C C G G G C C C C G G C G C C G C G C C C G G G G G C G G G G C C C C C G G C C G C C C C C G C C G C C C C C C C C G C G G C C C C C G C C G G C C G G G C C G G C G C G G C C C C C C G G G G C G G G G G C C C C C G C G C C G C G G C G G G C G G C C C C C G G G G G G C G G G G C C G C G G C G G C G C C G G G G G C C C C C G C C C C G G G C G C C G G C C G C G G G G G C C G C G G C G G C C G C G C G C C G C G G G G C G C C C G G C G C C C C G C G C C C G C C G C G G C C C C C G C G C C C C G G G C G G G G C C G C C G G G G G C G G G C C G G G +A T T T T T T T T T T T T T T T A T T T T T T A T T T A T A T A T A T A T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T A T T T T T T T T T T T T T T T T T T A T T T A T T T A A T T T T T A T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +T T T T T T A T T A T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C C G C G C C C C C C C G G G C C G C G G C C C G C G C C C G C C C C C G C C C C C C G G C C G G G G C C G G C G C G G C C G C C C G G G C C C G C C G C C C C G C C G G C G C C C C C G G C C G C C C C C C C C C C G C G G G G C C C C C G C C G C C C C G C G C C G C C C C G C C G C C G C G G C C G C G C C C G G C C C C G C G C C C G C G C C C G G G C C G G C C C C C C C C C C C G C C G C C G C C C G C C G C G C G G C C G G C C G C C C C G G G C C C C C C C C G G C C C G G C C C G G C C C C C C C C C C G G C C G G C C C C G C C C C G G C C G C C G G C G C +G G G G G G C G C G C C G G G C G G C G G G G G G C G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G C G G G G G G G G C G G G C G C G G G G G C G G G G C C G G G G G G G C G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G C G G G G G C G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G C G G G G G G G G G +T T T T T T A T A T A A T T T A T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A A T T A T T T T T T T T T T T T T T A T T T T T A T T T T A A 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T T A A A A A A A T T T T A A A T A A A A T A A A T A A A T A A A A T A A A A A +T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A A A A A T A A A A A A A A A A A T T A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T A A T T T A A A A T A T A A T A A A A A A A A A A A A A A T A T A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T +G G C C G C G G C C C C C G C C C C C C G C C C C C C C G G C C G C C G G G G G G C C C G C G C G C C C C C C C C C C C G G C C C C G G G C C C C C G C C C C C G G C G C C C C G C C C C C C C G C C C C G C C C C C C G C G G C C G C G C C G G G C C C G G C G G G G G C C C C C C C G C C C C C G G C C C C G C G G C G G G C G G C C C C C G G G C C C C C C C G G C C C C C G C G C C C C C C G C C C C C G C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C C C G C G C C C C C C C C C C C C C C C C C C C C C C C C C G C C C G C C C C G +G C G C C G C C C G G C C C G C C C G C C C G G G G G G G C C G C C G C G G G C C G G C C G C G G C C G C G G C G G G G C G G G G G C C C G C G G G G C G G G G C G G C G G G C G G G C G C G G C G G G C C G C C G G G C C C C G C C G C G G G G G G G G C G G G C G G G G C C C C C C G G C C C G G G G C G C C G C C C C G C G C C G C G C G C C C G C C C C G C C C G G G G G C G C G G C C C G C G G C G G C C C C G C G C C C C C G G G C G G C C G C C G C G C G G C G C C C G G C C G G C C C G G G G G G C C C C C C G C G C G G C G G G C G C C C C G G G G C C G C C +A T T T T A T T T T T T T T T T A A T A T T T A T T T T T T T T A T A T A A T T T T T T T T T T A T T T T T T A T T T T A A T T A T T T T T T T A T A T A T T T T T T T T T T T T A T T T T A A A A T T T T T T T T T T T T T T T T A A T A T A A A T A A T A A A T A A A T T A A T T T T T T T T T A A T T A T T T T A T T A T T T T T A A T T T T T T A T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T A A T T A T T T T A T T T T T T T T T T T T T T T A A T A A T T T T T T T T T A T A T A T T T T T T T T T T T T T T T T T T T T T T T A A A T T A T T +T T T T T T T T T T T T T T T T T T T T A A T T A T T T T T T T T T T A T T T T T A T T T T A T T T T A T T T T T A T A T T T T T T T T T T T A T A T A T T A T A T T T T T A T A T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T A T T T A T A T T T T T A T T T T T A T T T T A T T T T A T A T T T A T T T T A T T T T T A T T T T T A T T T T T T T T A T T A T A T T T T A T T T A T T T T T T T T A T T T T T T T T T T T T T T T T T A A T T T T T T T T T T A T T T T T T T T T T T T A +C G C G G G G C G C C G C G C G C G C C C C C C C C C C C G G C C G C C C C C C G C G G G C C G C G G C G C C C C C G C G C C C G G G G G C G C G C C C G C C C C C G G G C C G C C C G C G G G G G G C C C G C C C C C G G G G C G C G G C C C C C C G G G C G C C C C G C G G G G G G C G G G C C C G C C C G C C G G G C C C G G G C G G G C G G G C G G G G C G G G G C G C G G G C C C C G C G G G C C C C C G C G C G C C C G G G C C G C C G C C G G C C G C C C C C G G G G G G G G G G C G G C C G G G G G G C G G G C C C G C G G G C G G C G C G G C C G C C G G C G +C C C C C C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C G C C C C G C C C C G C C C C C C C C G C G G C C C C C C C C C C G C C C G C C C C C C G C C C C C C C C C C G G C C C C C C G C C C C C G C C C C C C G G C C C C C C C G C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C G C G C C C C C C C C G C C C C C G C C C C C C C G G C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C G G C C G C C C G C C C G G G C C C C C C C C C C C C C G C G C C C C C C C C C C C G C C C +T A T A T A A T A T T A A T T A A A T A T T T A T T A T T A A T A A A T T T T A T T T A A T T T T A T T T T T T T T A A A A T T A T T T T T A A A T T T A A T T T T A A T T A A T A T T T A A A T A A T T T A T T T A T A A T T T T A A A T T T T T T A A T T A T A T T A T A A T A A A T A A A T T T A T A T A T T T T A A T T A T A A A A A T A A A T T A T T T T T A T T A T T A T T A T T A T A A A T T T T T A T A T T T T T A A A T T A T T A A A T A T T A A A T T A A T T A A A A T A A T A A T T A A A A A A T A A A T A T A T T A A T A A T T T A A T A A T A A T T A +A A T A A A A T A A A A A A A A A A T A T A A A A T A T A A A T T A A T T T T A A A A A A A T A T A A A A A A A T A A A T T A T T A A A A T A A A A T A A A A A T T A A A T A A A A A A T A A A A A A T A A A A A T A T A T A A T A A T A T A T T T A A A A T A T A T T A A A T T A A A A A T A A A T A A A A A A A A A A A T T A A A A A A A T A A A A A A A T A A A A A T A A A A A A A A T A T A A A A T A A A A T A A A T T A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G C G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G +C G C C G G C C C C G C C G C C G C C G C C C C C C G C G G G C C C G C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C G C C G C G C C C C C C C C C C G C C G C C G C G C C G G C C G C C C C C C C G C G C C C C C G C G C G C C C C G C C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C G C C C C C C G C C C C C G C G C C G G C C G C G C C C C C G C C C C C C C G G C G C C C C G C G C C C C C C G C C C C C C C C G C C C C C C G C G G C C C C C C C C C C C C C C C C C C C G G C G C C C G C C C C G C C G G C C C C C C C G C G G C C C +T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T A T T T T T T A T T T T T T T T T A T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T A T T T T T T A T A T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T +A A A A A A A T A A A A A A A A T A T T T A A A A A A A T A A T T A A T T T T A A A A T A A T A T A A A T A A A A A A A A T A T A A A T A T T A A A T A A A A A T T A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A T T A A T A T T T T A A A A T A T A T T A A A A T A A T A A T A A A T A A A A A A T A A A A T T A A T A A A A T A A A A A T A T A A A A A T A A A A A T A A A A T A A A T T T A A T T T T A T T A A T A A T A T T A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A T T A T A A T A A A A A T A A T T A A T A A A A A T A A T A A +G G G G G C G G G C G G G G G G G G G G G G G G G C G G G C G G G G G G G G G C G G G G G G G G G C G G G G G G G G G C C G C G G G G G G G G C G G G G G G C G G G G C G G G G C G G G G G G G G C G G G C C G G G G G C G G G G G G C G C G G G G G G G G G G G C G G C G G G G G G G C G G G G G G C G C G G G G G G G C G G G G G G C G C G C G C G G G G G G G G C G G C G G C G G G C G G G C C C G G G C G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G C G G C C G G C G G G G C G G G G G G G G G G G G G G C G G G G G G G C G G G G G C G G G +C C C C C G C C C G G C C C C G G G C G C G C G C G C C G G G C C G C C C C C G G C G G C C C G C C G C G C C C C C G G G C C C C G C G C C G G C C C C G G G C C C G G C C C C G C C G C G C C C G C C C G G G C C C C G C C C C C C G G G G C C C C G C C C C C G C C G C G C C G G G G G C G C C C G C G C G C C C G C G C C G C G C G C C C G C G G C G C C C C C G G C G G G G C C C C C G C G G G G C C C G G C G C C C C C C G G C C C C C G G C G G G C G C C C C G C C C G C G C C G G G G G G C G C G C G G G G G C C C C G C G G G C G G C G C C G G C G C C G C C C +T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T A T T T T T T T A T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A A T T T T T T T T T T A T T T T T T A T T T T T T T T A T T T T A A T T T A T T T A A T A T T T T T T T T A T A T T T A A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A +G G C G G G G G C G G G G G G G G C G G C G G G G G G G G G G G C C C G G G G G G C G G G G C G G G G G G G G G G G G G G G G C G G G G G G G G G C G G C G G G C G G G G G C G G G C G G G G G C G G G C G G G C G G G G G G G C G G G G G G G G G G G G C G G G C G G G G G C C G G G G G G G G G G G C G G G G G G G G G G C G C G G G G G G G C G G G G G G G G G G G C G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G +G G G G G G G G G G G G G G G G G G G C C G C G G G G G G G G G C C G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G C G G G G G G G G G G C G G C G G G G G G C G G G C G G G G G C C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G +T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T A +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A +G C C G G G G G C C G C G G G G G C G C C G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G C C G G C C G G G G G G G G G G C G G G G G G C G G G C C C G C G G C G G C G G G G C C G G G G G C G G G C G C G G C G G G G C G G G G G G C G G C G G C C G G G G G G G G G G C G G G G G G G G G C G G G G G C G C G G G G G G G G G G G G G G G C G G G G G C C C G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G C G G C G C G G G G G G G C C G C C G G C G G G G C G G G G G G C G G G G G C G C G G G G C G G G G C C G G C G G C +G C C G G G G G C C G C G G C G G C G G G G C G G C G G G C G G G G G G C C G G G G G G G G G G C G G C G C G G C G G C C G G C C C G G G G G C G G G G G G C G G G C C G C C G C G G G G C G G C C G C G G G G G C G C C C C C C G C G G C G C C C G G G G C G C C C C C G C C C G G G G G C G G G G C G G C G G G G G G C C G G G G G G C G G C G C G G G G G G G G C G C G G G C C C C C G G G G C C G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G C G G G G G G G G C C G C G G G G C G G G G G G G G G C G G C G C G G G C G G G G G G G G C C G G C G G C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T A T T T T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T +A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A T A T A A A A A A A A A A A A A A A A A A A T A T T A A A A A A A A A A A A A A A A A A A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A 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C C C G G G C G G C G C C C G C C C C C C G G G C G C G G G C C G G G G C G C G G G G G G C G C C G G G G G G C G C G C G G C G G G C C C C C G G G C G C G C C C G G G G G C C G C G C C G C C G G C C G C C G G C G G G C G C +T A T T T T T T T T T T T T T T A T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A A A T A T T T T T T T T T T T T T T T T T T T A T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T A T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T A A A T A T T T A T T T A A A T T T T T A T T T T T T T A T T T T T T T T T T T T T T A T A +T T T T T T T T T T T A A T T T T T T T T T T A T T T T T T T T T T T T T T T T T A A T A T T T T T T A T T T T T T T A A T T T A T T T A T T A T A T T A T A T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T A A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T A T A A T A T T T T A T T A T A A T T T T T A A A A T A A A A A T T A A T A T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T A A A A A T T A T T T T A T T T T T T A T T T T T T T A T T T T T T A T T T T T T T T T A +G C C G C C G G C C G G G G C G G C G C G G C G G C G G G G G G C C G G G G C C G G G G G C G G G G G G G C C G C C G G G G G C G C G G G G G G G G G G G C G G G G C G G C G G C C G G C G G G C C C C C C G G C C G C G C G G C G C G G C G G G G C G G G G G G G G G C G C C C G G G C C C G G G G G G G C G G C C G G G G G G G G C C G G G G G G G G G G G G G G G G C G G G G G C C G G C G G G G G G C C G G G C C G G G G G G C C C G G C G G G G C G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G C G C G C C G G C G G C G G G C G G C G G G G G G +G C C G C C G G C C G G G G C G G C G C G G C G G C G G G G G G C C G G G G C C G G G G G C 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A A T T A T A A T T T T T A +A T T A T A T A T T A A T A A A A T T T A A T A T T A A A T A A T T A A T T A T A T A A A T A T T A T T T A T A A A A T A A A T A T A T A A A T A T A A A T T A A A T T A A T T A A T A T A A A T T T T T A A A T T A T T T T T T A T A A T A T T T T A T T A T T A T A T A A A A A T A A T T A A A A T T A A T A A A A A T T A A T A T A A A A T T T A T A A T T T A T A T A A A T T T T A A A T A T T A A A A A A A T T A T A A T A A A A A T A A A A A A A A A A A T A A T T T A T A A T A T A A A A T A T A T A A A A A A A A T A T T A A T A A T T A T A A A T A A T T A A +G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G +G C C G G G G G C G G G C G G G G C C C G G C G C G G G G G G G C C G G G G G C G C G G G C G C G C G C G G C G G G G G G G C C G G G C C G G G G G G G G C G G G G G G G G G G G G G G G G G G C C G C C G G G C C G C G G C C C G G G G G G G G C C G G C G G G G G G G G G G G G C G G C C G G G G G C G C G G G G G G G G G G C G C G G C G G C G G G G G G G C G G G C G G G G C C C G G C C G G G G G G G G G G C G G G G G G G C G G G G G G G G G C G G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G C G G G C G C C G G C G G C C G C G G G C G G G C G G +T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A T T A T A A A A A A A A T A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G C G G C G C G G C G C C G G G C C C G C G G G C C G G G C G G G C C G C C G C C C G G G C C C C C C C C G C G C G G C C G C G C C G C C G G C G C G G G G C G G C C C G C C C C G C G C C G G G C C C C C C G C C G C C C C C G G C G G C G C C C C G C C C C C C C C C G C G C G C G G C C G G G G C C G C C C C G C G C C C G C G C C C C C C C C C C G G C C C G C G G C C G C C G G C G C C G C C G G C C G G G G C C C G G C G C G C G C C G G G G C C G G C G C G G C C C G C C C C C C G G C G C G C C C G G G G C C C G C G C C G C C G G G C G C G G G C G C C C C C +C C G G G G C C G G G C C G G G C G G G C G G C G G G G G G G G G G C G G G G G G G G G C C C C G C C C G G G G G G G C C G G G C G C C C G G C G C G G C G C G G C G G G G G G G G C G C G G G G C C G G G C G G G G G G C C C G C C G G C G G G G G G G G C G G C G C C G C G C C G G G C G G G G G C G G C G G G G C C G G C G G G C G C C G C G C G C G C C C C C C C G G C G C G G G C C C G G C G G C G C G G C G C G G C G C G C G G C G G G C G G C C G G G G C C G G C C G G C C C C C C G C G G G G C G G G G G C C G C C G C G G C C G G G G G C G G G C G C G C G C +A T A A T T A A A T A A A T T A T A T T A A 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A T T T T A T A A T A A A A T T T T T A A T A A T T T A T T A T T T T A T A +G C G G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G G G G C G G G C G G G G C G G C G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G C C G C G G G C G G G G G G G G G G G G G G G G +C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A A T T T T T T T T T T A T T T T T T T T T T T T T T T A T T A T T A A A T T T A T A A T T T T T T A T T T T A T T A T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A A T A A T A T T T T T T T T A T T T A T A T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A A T A A T T A T T T T A T T T T T T A T T A T A T T A A T T T T T T T T T T T T T T T A +T A T T A T T T T T T T T T A T T T T T A T T A A T T A T A T T T T A T A A T T T T T T A T A A A A T A A A A T T A T T T A A T T T T T A A A T T A T T T T T A A T T A T T T T T T A T A T T T T T T T A T A T T A T T A T T T T T T T T T T A 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C G G C G C C C C C G G C G C G C C C C C C C G C G C C C C C G G G G C C G C C G C C G C C G G G C G C G G G G C C C G C G +G G G G C G G G G G G G G G C G C G C C G G G G G G G C G C C G G G G G G C G G G G G G G G G G C G G G C G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G C G G G C G G G G G C G G G G G G G G G G C C G G G C G G G C G G G C G G G G G G G G G G G G G G C G G G C G G G G G G G G G C G C G C G G G C G G G G G C C G G G G G G G G G G G G C G G C G G C G G G C G G G G G G G G G G G G G G G C C G G G G G G C C G G G G G C G G G C C C G C G G G C G C C C C C G G G G G C G G G G G G G C G G G G G G C G G G G C G C G C G +A A T T T T T T T A T T T T T A A A A A A T T A T T T A T T A T T A A A A T A A T A T T A T A T T A A T T T A T A T A A T A A T T A A A A T T A T A T T T A T T A T T T T T T A A A A A A T T T T A A T A T A T A T T A T A A A T T A A A A A T T A A A T T A T T A A A A T A T A T T T A T A T T A T A A A T T T T T T T A A A T A T T T T A A A A A A T T T A A A T A T T A A T A T T A T T A A T T T T A T A T T T A T T A T T A T A T T T A T T A T T A T A T A A A T T T T T T T A T A T A T T A T T T T A T T T T T A T T A T T T A T T A T T T A T A A T T T A A T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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T T A T T T T T T T T T A A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A A T T T T T A T A T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T A A T T T T T T T T T T A T T T T T T T A A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T A T A T +A T T A T A T A A A A A A A T T T A T A T A A T A A A A A T A A A T T A T T T T A A A A T A T T T T T T T A T A T A A T A T T A A A A A T A A T A A A A A T A A T A T T A A A T T T A A T A T T A T A T T A T A T A A T T T T T A T T A A T A T T T A T T A A T T T T A T A A A A A A A T T A T A A A T T T A T A A A A A T T T A T A T T T T T T T T A A A A T T T A T A A A A A T A A T A A T A A T T A A A T A A A A A A A A A A A T A A A T T A T A A T A T T T T A A A T A A A T T T T T T T A T A T T T T T A A A A T T A T A A A T A T A A A A T A T T A T A T A T A T A +C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C C G G C C C C G C C C C C C C C C C C C C G C C G C C C C C C G C C G C C C C G C C C C C C C C C C C C C C G C G C C C C C C C C C C C C C G G C C G C C C C C C C G G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C C C C C G C C C G C C C C G C C C C C C C C C C C G G C C C C C C C G G C G C C C G C C C C C C C C C C C C C C C C +C C G C G C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C C G C C C C C C C C C G G C C G G C C C C C C C C C C C C C C C C C C C C G C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C G G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C G C C C +A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A T A A A A A A A A A A A A A A A A T A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A T A A A T A A A A T A A A A A A A A A A A T T A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A A A A T A A A T A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A T A A A A A T T A T A A A T A A A A A A A T A A 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G G G G G G G G G C G G G G G G C G G G G G G G G G G C G G G G C G C C G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G C C G C G G C G G C G G G G G G G G G C C G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G +A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A A A T A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A +T A T T A T T T T T A A A T T A T T T T T A T A T T T A T A T T T T T T A A T T T A T T A A T A A A A T A T A A A T T A A A T T A A T A T T T A T A T A A T T T T A A A T A T A T A T T A A A A T A A T T T A A A T A A T T T T T A T T T T T A A T T T A A T A A A T A A T T T A T T A T T T A T T T A A T A A A T T T T A T A T T T A A A T A A T A T T A A A A A A A T T T T T A T T T A T A T T A A T T T A T T A T T T T T T T T A T T T A T T T T A A A A A T T A T T A T T T A A T T A A A T A T A T A A A T T A T A T T T A A A T T A A T T A T T A T A T A T T A T A T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G C G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T A T T T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A T A A T A A A A A T A A A A T A T T A A A A A A A A T T A A A T T A T A A A A A A A A A A A A A A A A A A A A A T A A A T A A T A A A A A T A A A A T T A A T A T A T A T A A T T A A A A T T A A T A T T A A A A A A A T A A T T A A A A A A A A A A A A A A T A A A T A A A A A T T A A A A A A A A A T A T A A A A T T A T A A A A A A T A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T T A A T A A A T A A A T A A A T A T A T A A A A A A A A A T A A A T A T A A A A T A A A A A A A A T A A A +G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G 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G G G C G G C C C G C C C C G G C C C C C G G C G G G C C G C C C C G C G C C C C C C G C C G G G C G C G C C C G C C C C C C C C C C C G C G G G +T T T T T T T T T T T T T T T T T T T T T A T A T T T T T A T T T T A T T A T T T T T T A T T A T T A T A T T T T T T A A T T T A T A T T T T A T T T T A T T T A T T A T A T A T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T A T A T T A T T A T A T T A T T T T T T T T T T T T T T A T T T A T T T T T T A T T T T T T A T A A T A T T T T A A T A A T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T A T T T T A T T T T A T T T A T T A A T T T T T T T T T T T A T T T T T T A T T T T T T T T A T T T +T T T T A T T T T T T T T T T T A T A T T A T T T T T T T A T T T T T T T A T T T T T T A T T T T A A T A T A T T T T A A T T T A T A T T T T A T T T A T T T T T T T A T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T A T A T T A T T A A A T T A T T T T T T T T T T T T T 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G G G G C C C G C C C C G C G G C C C C G C C C +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G C G G G G G G G G G G G G G G G G +A A A T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T A T T T T A T A T T T A T T T T T T T T A T T T T T T T T A T T T A T T T T T A T T T T T T A T T A T T T T T A T A A T T T T T T T T T T T T T T T T T T T T A T T A T A T T T A A T T T T T T T T T T A T T A T T T A A T T T T T T T A T T T T A T T T A T T T T A A A T T T T T T A T T T T T T T A T T A A T T T A T T T T T A T T T T A T A T T T A A A T A T T T A A T A T T T T T T A T T T A A T T A T A T A T T T T T A T A T A T T T T T A T T T T A A T T T T T T T T T T T +A T A A A A A T T T T T T A A T T A T A A T T A T A A A T A A T T T T A T A A T T A T A A T A T A A A A A T T T T A A A A A A A A T A A A A A A T A A A T A A A T T T T T T T A T A A A A A A A A A T A A A A T T A T T A A A A T T A T T A A T A T A T A A A A A T A A A T A A A A T T T A A T T A A A T A A A T A A A A T A T A T T A A A A A T T T A T T T A A A T A A A A A A T T A A A A A A A A A A A A T A A A A A T T A A T A A T T A A A T T T A A A A A A T T A A A A A T A A T A A A T A A A A A A A A A A A A A T T T T T A A A A T A A T A T A A A A T A T T A T A +G C C G G G C G G C G G G G G G G C C C G G C G G G G G G C G G G G G C G G C C G G G G C G C G C C C C G G C C G G G C C G C G C G C G C C G C G C G C G C G C G G G C G G G C C C C G G C C C G C G G G C C G G G G G G C G G G G C C C C C G G G C C C G C C C G G G C C C G G C G G C G C G C G C C G G G C C G G G G G G G C G G G C C G C G C G G G G C C C C G G G G G C G G G G G C G C G G C C G G G C G G G G G C G G G G C G C C G C C C G G C G G G C C G C G G C G C G C C G G C C G G C G C C C C C G G G C G C G C G G C G C C C G G C C G C C G G G C G G C G G +G C G G G G C G C C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G C G G G C G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G C G G G G G G G G G G G C G G G G C C G G G G G G G C G C G G G C C G G G G G G G G G G G G G C G G G G G C G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G +T T T T T T T T T T T T T T T T T A A A T T T T T A T T T T T T T T T T T T A T T T T T A T A T A T A A T T T T T T T T T T A T A T A T A A T A T T T A T A T A T T T T T T T A T T A T T T T T T A T A T T A T T T T T T T T T T A A T T A T T T A A T A A T A A T T T A T A T T T T T T T A T T T T A T T T T T T T T T T T T A T T A T A T T A T T T T T A A A T T T T T T A T T T T T A T T T T A T T T T T T T T T T T T T T T T T A T T A A T T T T T T T A A T A T T A T A T A A T T A T T T A A A A A A A T T T T T T T A T T A T A A A T T T A T A T T A A T T T T T T +A A T A A A A A A A A A A T A A A T T A A A A A A A A A A A A A A A A A A A T A A A A A T A A A T T A T A A A A A A A A A A T A A A A A T A A T A A A T A A A A A A A A A A A T A A T T A A A A A T A T A A A A A A A A A A A A A A A A A A A A A A T A T A A T T A A A T A T A A A A A A A T A A A A A T A A A A A A A T A A A T A A A T T A A T A A A A A T A A A A A A A A A A A A A T T A T A A A T A A T A A A A A T A A A T A T A A A A T T A A A T A T A A T A A T A T T T A A T A A A T A A A A T T A T T A A A T A A A A A A A A T A A A A T T A T A A A A A A A A A A +G G G C C C G C G G C C C G C C C G G G C C G C G G G C C C C C C G C C C C G G C C C C G G G C G G G G C C C G C C G G G C G C G C G C G G G G C C C G C C G G G C C C G C C G G C G G C G G G C G C G C G G C C C C C G G G G C G G C C G C C C G G C G G G G G C C G G G G G C G C C G G G C G C G G G C C G G C C C G C C C G C C G G G C G G G G C C C G G G C G G G C C G G G C C G G C G C G G G C C G G C C C C G G C C G C G C G G C G G G C C G C G C G G C G G C G G G C G G G G G G C C G C G G G G G C C C G C G G G C C G C G G G C C G G C G G C C G C C C C G C +C C C G G G C G C C G G G C G G G C C G G G C G C C G G G G C G C C G G G G C C G G G C C G G G C G G C G G C C G G G C C G C G C G C C C C C C G G G C G G C C C G G G C G G C C C C C G G C C C C G C G C C G G G C G G C G G G C C G G C G G G C C G C G G C C G G G C C C C G C C G C C C G C C C C C G G C C G G G C C G G C G C C C C G C C G C G G C C C C G C G G G G G G C G C C C G C C G G C C C C C C C C C C C C C C C C C G C C C C C G G C G C G G C G C C C C C C C G C G C G C G G C G C C G C C C G C C C C C C G G C C C G C C C C C G C C G G C C G G G C G +T T A T A A T A T T A A T T A A T T T A A T T T A T A T A T T T A A T T T T T T T T T T T A A T T A A T T T T T A A A T T T T T T A T T T T T T T T A T T T T T T T T T T T T A T T A T A A T T A T T A A T A A T A A A A T A A T T T T T T T T A A T T T A A T T T T A T T T T T T T T T A T A T T T T A A A A T T T A T T T T T A T T T T T T T A T T T T T T T T T A A A T A A T T T T T A A A A A A T T T T A A T T T T T A T T A T A T T T T T T T A A T A A T A A T T T T T T A T A A A A T A A A T T A T T A A A A A T A T T T T A T A T A A T T T T T T T A T T T T A T +T T T A A A A A T T A A A T A A A T T A A A T A A T A A A T A A A A A A A A T T A A A A T A A A T A A A A A A A A A A A A A T A A A T A T T T T A A A A A A T T T A A A A A A T T A T T A T A A A A A T T T A T T A A A A A A A A T A A A A A A A A T A A A T A T A A T T T A T A T A A T A A A A A T T T A A A T A A A A A A A A A A T T A A T T A T A A A T T T A T A T A A A T T A T T A A T A A A T A A T A A A A A T A A A T T T A A A A A A A T A T A T A A A T T T A A T T A A A A A A T A A A A A A A A A A A A T A A A T T A T A T A T A A T A A T T A A A A A A A A T +G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C G C G C C G C C C C C C C C C C C C C +G G G C C C C C C G C G C G C G C G G G C G G C C G C C C G C C C G G G G C G C C G C G G G G G C G G C C C C G C C G C G C G C G G G C G G G G C C C G G C C G G G C G C C C G G C C G C G C C G C C G C G G G G G C G G C G G C G G G G G G G G C G G C G G C G G G G G G C G G G C C G C C C C C G G G C G C G C C C G C G G G C C C C C C G G C G C C C G G G G G C G G C G G C C G G G C G C G G G C G G C C C G G G C G G G G G G G C G C C C G C G C G C G C G G G C G G G G G C G C G G G C C G C G G C C C C C G C C C G G G G C G G G C C G C G G G C C C C G C C C G +T A A T T T T T T A T A T T T A T A A A T A A T T T T T T A T T T T A A A T A T T A T A T A A A T A A T T T T A T T A T A T A T T A A A A T T A T T T T A T T T A A T T T T T A A T T A T T T T A T T A T A A T T A T A A A A A T A T A A A A A A T A A A A A T T A A A T T T A T A T T A T T T T T T T A T A T T T T T A T T A A A T T T T T T A T A T T T A T T A A T A A T A A T T A A T T T T A A T T A A T T T A T A T A T A A T A A T A T T T T T T T A T A T A T A T T A A A A A A T A T T T T A T T A A A T T T T T T T T T A T T T A T T T A T A T A T T T T A T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A +G G G C C C C C G G C G C C C G C C C G C C C G C C C C C C C C C G C C C C G G C G C C G G G C C G G C C C G C C C G G G C G C G G G G G G G C C C C G C C C G C C C G C C C G G C C C C G G G G G G G G G G G G G C G C G C C C G G C C C C C C C G C G G G G G C C G C G C C C G C C G G C C C C G G C C C C G C C C G C C C G G C G G C C G G G G G C C G G G C G G C C C G G C C C G G C G C C G G C G C C C C G C C C G C C G G C G C G G C C G C G C C C G C C G C C C C C C C G C C G G C C C G C C G G G C C C G C C C G G G G C C G G C C G C C G G G C C C C C C C G +G C G G G G G G G G G G G G G G G C C G G C C G G G G G G G G G G G C C C G C G G G G C G C G C C G G G G G G C G G G C G G G G G G C G G G G G G G G G C G G G C C G G G G G G C G C C G G C C G G G G G C G G G C G G C G C C C G G C C C C C C C C C G G G G G C C G C G G G G G G G G G G G G G G G C G C G C G G G C C C C C G G G G C G G C G G G G G C G G C G G G C C G G G G C C G G G C C G G G G C G G G G G G G G G C C G C G G G G G G C G G G C G G G C C G G C C G G C G C C G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G C G G G G G G C G G G G +T A T T A A T T T T A T A T T T A T T T A T T T A T A T A A T T A A T T T T T T A T T T T T T T T T T A T A T T A A T A T A T T T T T T T T T T A A A T T A T T T T A A A T A T T A T T A T A A T T A T T T T T A T A A T A T T T T T T T T T T T A T T T T T T T T T T T T A A A T T A T T T A A T T T T A A A T A A A T T A T T T T T T T A T T T A T T A T T A T T T A T T T T A T T T T A T A T T T T T T A A A T A A A T A A T T T T A T T T A T T T T T A T T T T T A A T T A T T T A T T A A A T T T T T T A A A T A A A T T A T A T T T A A T T T T A T A A T T A T A T +A T A T T T A A A A T A T A A A T A A A T A A A T A T A T T A A T T A A A A A A T A A A A A A A A A A T A T A A T T A T A T A A A A A A A A T A T T T A A T A A A A T T T T T A A T A A T A T T A A T A A A A A T A T T A T A A A A T A A A A A A T A A A A A A A A A A A A T T T A A T T A A T T A T A A T T T A T T T A A T A A A A A A A T T A A T A A T A A T A A A T A A A A T A A A A T A T A A A A T A T T T T T T T T T T A T A A T T A A T A A A A A T A A A A A T T A A T A A A T A A T T T A A A A A A T T T A T T T A A T A T A A A T T A A A A T A T T A A T T T A +G G G G G G C C C C G C G G C C G G G G G G G C G C G C G G C C G G G C G C G C G C C G G G G C C C C G C G G G G G C G C G G C G C G G G G G G G G G G G G C C G G G G G G G G G G C G G G C C G C G G C G G G G C G G C C C C G C G C C C C G C G G C C C G C C G G G G G G G G G C G G C C G G C G G G G C G C G G G G C G G G C C G C C G G C C G C C G G G G G G C G G C C C G G G G C G C G C G C G G G G G G G G G G G G G G G G G G G C C G G C G C G G C C G G G G G G C G C C C G G G G G G G C G G C C G G G C G G G G G G G G C G G G G C C G G G C G G C C G G G C +C C G C C C C C C C C C C G C C C G G G C G G C C G C G C G G C C C G C G C G C G C C G C G G C G C C C C C G G C C C G C C C C G C G C C C C C C G C G G G G C G C C C C C G G G C C G C G C C G C C C C C G C C C C C C C C C G C G C C C C G C C G C G C G C C C G C G C C C C G C C C C C C C C C C G C C C C C C C C C C G G C C C C G C C C C G C C C G C C C G C C G C C C C C G G C C C C C C C G G G C C C G C C C G C C C G G G C G C C C C C G C G C C C G C G C C C C C C C C C G C C C C G C C G C C C C C C C C C C C G C C G G C C C G G G G G C C C C C C G C C +A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A T A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A T A A A T A A A A T A A A A A T A A A A A A T A A A A A A A A A A A A A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A T A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +C G C G G C G G C C G G G G G C C C C G G G C C G C G C G C G C G G G C G C C C G C G C G C C G C C C C C C G C C C G C G G G C G G C C G G G C C C G G C C C C G G C G C C C G C G C G G C G G G C C C G C G G C G G C G C G G G G C C C C C G C G C C G C G C C C C G C G C C C C C G C G C G C G C G G G G G G G C C C C G G C C G G C C C C C C C G G G C G G C C C G C C C C G G G C C C C G G C C C G C G G G G G G G G G G G G C C G G G C G G G G C C G G C G G C G G G G G G G G G G C G C G G C G G G G G G G C G G G C G G C G G G C G G G G C C G C C C C C G G G G +G C G G C G C C G C C C C C C G G G G C C C G G C G C G C G C G C C C G C G C G C G C G G G G C G G G G G G C G G C C G C C C G C C G C C C C G G C C C G G G G C C G C G G C C G C G G C G C C C G C G C C C C C C C C C G C C C C G G G G G C G C G G G G G G G G G C G C G G G C G C C C G C C C G C C C C C C C G G C G C C C G C G G G G G C C C C C C G C C C C G C G G G C C C G G G G G G C G G G C G C C G C G C C C G C C C G G C C C G C C C C G G C C G C C G C C C C C C C C C C G C G C C G C C C C G C G G G C C C C C C G C C C G G G C G C C C G G G G C C C C +A A T T T T T T T T A A A A T T T T T A T T T A A T A T T T A T T A T T T T T T T T A T T T T T T T T T T T A T T T A T A A T T A A T T T T T T T T T T A T T T T T T T T T T T T T T T T T A A A A T T A T A A T T T T T T T T T A T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T A T A A A A T T T T T T T A T T T A T T T T T T T T T A T T A T A T T A T T A T A A T T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T A T A T T T T A A T T A T A A T A T T A T A A A A T A T T T T A T A A T T A A A T A T A T T T T T A T T T A T A +A A T A A A A T T A A T A A A A A T T T A A A T A A A A A A A A A A A A A A A T A A A T A A A A T A A A A A A A A A T A A A A A A T A A A A A T A A A A A A T A A A A A A A A T A A T A A A T T T A A A T A T A A A A T T A A A A T T A A A A A A A A A A A A T A A T A T T A A A A T A T A T A A A A T T A T A A A A A A A A A A A T A A A A A A A A A T A A T A T A A T A A A A A T A A T A T T T T T T A T A A T A A T A A A T A A T T A A A A A A A A T T A T A T T T T T T T A A A A A T T A A T T A T T A A A A A T A A A T T T A A A T T A T A A T A A T A A T A A T A A +C G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G C G C G G G G G C G G G G G C G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G C G G C G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C C G G C C G G C G G G G G G G G G G G G C G G C G G G C G G G C G G G G G C C G G +C G C G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C C G G G G G G G G C G G G G G G G G G G G G G G C G C G G G G G C G C G G G C G G G C G G G G G C G G G G G C C G G G G G G C G G C C G G G G C G G G G G G G G G G G G G G C G G C C G C G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G C G G G G G G C G G G C G G G G G C C G G +T A T A A A A A T A A A A A A A A A A A A A T T A A A A A A T A A T A A A A A T A T A T A A A T T A A A A A A A A A A A T A T A T A A A A T A A A A A A T A T A A A A A A A A A A A A T A A A A A A T T T A A T A T A T T T A A A A A A A A A A A A A A T T T A A A A A T T A A A A T A T A T A A T A T T T A A A A A A A T T A A A T T A T A A A A A T T T A T A T A A A A A A A A T A A A A T T A T T A A A A A A A A A A A A A A A A T A A A T A A T A T A A A T T A A A A T T A A A A A A T T A A A T T A A A A T A T A A A A T T T A T A T A A T T A A T T A T T A A A A A +A A A A A T A A A T A A A A A A T A A A A A A A A A A A A T A A A A A A A A T A A T A A A A T A A T T A A A A A T A A A A A 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G G G G G G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C C G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +A A T T T T T A T A T T T T T T T T T T T T A T T A T A T T T A A T T T T A A T T A T A T T A A T A A T T T T T T T T T T T T A A A T A T A T T T A T T T T A T T T T T T T A T T T A T A A T T T A T T T T T T T T T A A T T T T A A T T T T T T T A T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T A T A T A T A T T T T T A A A A T T A T T T A T A T T A A T T T T T T T A T T T A T A T T T T T T T A T T T T A T T T A T T A T T T A T T T T A A T T T T T T A T T T T T T T T T T T A A T T T T T T T A T T A T T T T T T T T T A A T A T T T A A T T +A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A T A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A +C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G C G C G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +A T A A T A A A A A A T A A A A A A A T A A A A A T A T A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A T A A A T A T A T A A A A A A A A A A A A A A A A A A T A A T A A T A A 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C C G C G C G G C C G G C G G G G G G G C G G G G C C G C C G C G G G C G G C G C G C G G G G C C G G G C G G C C C G G G G G G G C G G G C C C G G G G G G G G G C G G C G C G C G G G C G G G G G G G G G C G G G G G G G C C G C G G G G C G C G C G C G G G G G G G G C C G C G G G G G C G G G G G G G G G G C C G G C C G C G G G G G G G C G G G G C C G G C C G G C G C G C G C C C C G G C G G G C G C G G G G G G C C G C C G G G C G G C C C C C G C G C G G C C G G C C C G C G G C G C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G G C G C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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A A A A A A T A A T A A A A T T A T T A A A A A T A A T A T A A A A T A A A T A A T T A A A T T A T T T A A A T A A A A A A A A A T A A T A A A A A A A T T A T A A A +C C C C G C C C C C C C G C C G G C G C C C C C C C C C C G G C C C C C C C C C C C G C G G C C C C C C G C G C G C C C G C G C C C C C C C C C G C G C C G C C C C C C C C C C G G C C C C C C C C C C C G C C G C C C C C C C C C C G C C C C C C C C C G C C C C C C C C G G G G C G C G C G G G C C C C G C G G G C C C C G C C C G G C G C C C C C C G C C G C C G C G C C C G C G C G G C C C C C C C C G C G G C C G C C C C C C C G C C C G G C G C G C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C G G C C C C C C C C G C +G G C C C C C G C C C G C C G C C C C G C C G G C C C G C C C G G C C C C G C C C G C G C C G C C C G C C C C C C C C C C C C C G C C C C C C G C G C C G C G C C C G C C G G G C C G G G G G G G G C G G C C C C C C G G G C C C G C C C C C C C G C C C C C G G C C G G C C C 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T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T A T T T T T T A T T A T T T +T T T A T T T T T T T T T T A T T T T T T T T A T T T T A T T T A T T T T A T T T T T T T A T T T T T T T T T A T T T T T A T A T T T T T T T A T A T A A T T T T T T T T A T A T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T A T T A T A T T T T A T T A T A T A T T T T T T A A T T T T T T T T T T T T A T T T T A T T T A T T T T T A T A T T T T T T T T T A T T T A A T T T A T T T T T T T T T T T T T T T T T T A A T T T T A T T T A T T A T T T T T T A T T T T T T T T T A T A A T T T A T T T T T T T T T T T T T A T T A T T A A T T A T T T +C C G C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C G C G G C C C G C C G C G C C C C C C C C C G C G C C C C C C C C C C C C C C C G C C C C C C C C C G C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C G C G C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C G C C C C C C G C C C C C C +G C G G C C C C C C C G G C G C G G G G C G G G G C C G G C G G G C G G G G G G C G G G C G G C G C G G C C C G G G G G C G C C G C G C G C C G G C G G G C G G G C G C C C G G G C G C G G G G G G G G G G C G G G G G G G G G G C C G C C C G C G G C G G G G G C G G C G C C G C G C G G G G C G G C G G G G C G C G G C C G G G G G G G C C G C C G G G C C G C C C G C C G C C G G G C C C C G G G C C G C C G C C G C G C G C C G G C C G C G G G G C G G G C G G C G G G G G G G G G C G G G C C G G C G G G G G C G C G G C C G G G C C G G G G C G G G C G G C G C G G +A A T A A A A T A A A T A A T A T T A T A T T A A A A A T A T A T A A A A A A T A A T A A A T A T A T T A A T T A A A A A A A A A A A A A A A A T A A T A A T A A A A A A A A A T A A T A T T T T A A T T A T A A A A A T A A A 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C G G C C G G G G G G G G G G G G G G G G C G G C G G C G G G G G G G G C C G G C G C C C C G G C C G C G G G G G C G G G G G G G G G G G G C C G G C C G C G G C C C G G C G G C G G C G G C G C G C C G G G G G G G G G G C C C G C G G C G G G C C G C C C G G G G G C G G C G G G G C C G G C G G G G G C G G C C G G G G G G G G G C G C C C C C G C C C G C G G G C G G G C G G C G C G G C C C C C C C G C C C G G G C C G C C C C C C G C G C G G G G C G C G G G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G C G G G G G G G G G G C C C G G C C G G G G G G G C G G G G G G G G +A A A T A A A T A A A T A A T A T A A T A A T T T A A A A A T A T A A A A A A A A T T A A T A A T A T A A A T A T A A A A T A A T A A A T A A T T A A A T A T T A A T A A A A A A A A T A T T T A T A A A A T A A A A A T A A A T T A T A A A A A T A A A T T T T A A T T A A T T A T T T A A T A T A T A A A A A T A A A A A A A A A T A A A A A A A T A T A T T T A A A A A T A A A A A A A T A A A A A A A A A T A A A T A A A A A A A A A T A T A A T T A A T T A A A A A A A A A T A A T A A A A T T A T T T T A T T T A A A A A A T T T A T A T T A A T A A T T A T A T A +A A A T T T T A T T A A A A A T A A A A T A A A A T A T A T A T A T T T T T T A T A A T T T A T A T T A T T A A A T T T T T T T A T T T T T T A A A T A A A A A T T T T T A T T A T T A A A A A A A T A A T A T T T T T A T T T A T T T T T T T T A T T T A A A A T T A A A T T T T T A T T A T T A T A T A A T T T T A T T T T T T A A T A T T T T T A A A T A A A T T T T T T T T T T T T T A A T A A T T T T T A T T A T T T T T T T A T T A T T A A T A T A A T T A T T T A T T T A T T A A A T T A A T A A A A T A T A T T T T T T A A A T A A A A T T A T T A A T A T T T +G G G C C C C G C C G G G G G C G G C G C G G G G C G C G C G C G C C C C C G G C G G C C C G C C C C G C C G G G C C C C C C C C C C C C C C G G G C G G G G G C C C C C G C C G C C C C G G G C C C G G C G C C C C C G C C C G C C G C C C C C G C C C G G G G C C G G G C C C C C G G C C C C G C G C G C C C C C G C C C C C C G G C G C C C C C G G G C G G G C C C C C C C C G C C C C G G C G G C C C C C G C C C C G C C C C C C C C G C G G G C G C C G G C G C C C G C C C G C C G G G C C G G G G G G G C G C G C C C C C G G G G C G C G G C C G G C G G C G C C C +G C G C C C C C C C C G C C G C G G G G C C G C G C C C C C G C G C C C C C G G C C G C C C G C G C C G C C G C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C G C C C C C G G G G G C G C C G C G C C C C C C C C C G C C G C C C C C C C C C C C C G C C C C G C C C C C C G C C C C G C C C 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A T T A A A A A A A T A A T A T T T T T A T T T A T T T T T T T T A A T T A A A T T T A A A T T T T A A A T T A T A T A T T T T T A T A T A T T T T A A T A T T T T T A A A T A A A T T T T T A T T A T T T T A A T A A T T T T T A T T A T T T T T T T A T T A T A A A T T T T A A T T T T T A T T T A T T A A A T T A A A A A A A T A T A T T T A A A A A A A A T A A T A A A T A A T A T A T +C C C C C C C G C C G C G G C C C C G C C G C G G C G C C C C C C C C C C G C C C C C C C C C C C C C G C C C G G C C C C C C C G C C C C C C G C G C G G G C G C C C C C C C C G C C G G C C C C G C C G C C C C C C C G C C C C C C C C C C C C G G C C G G G C C C G C G C C C C C C C C C C C C C C C C C C C G C G C C C C C C G C C C C C C C C C G C C C C C C C C C C G C C C C C C C G C C G C C C C C C C C C C C C C C C C C G C C C C C G G C C C C C C C C C C C G C C C C C C C C G C C C C G C C C C C C C C C C C C C C C G C C C C G G C C C C C G C C C C G C +C C G C C G G G G C G G G G G C G C G C C G G G G C G G G G G G G G G G G G G G G C G G G C G G G C G G C C G G G G C C C G G C G C G G G C C G C G C G G G G G G C G C G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G C G G C G C G G G C G G G G C G G G G C G G G C G G C G C G C C C C G G G C C C G C G G G G C G G G G G G G G G G G C G G C C G C G G G G C G G G G G C G G C G G G G C G G G C G G C G G G G G G G G G C G G G C C G G C G G G G G G G C G G G G G G G C G G G G G G C C G G G G G G G G G +T T T T T T T T T T T A T T A T T T T T T T T T T T T A T T T A T A A A A T T T T T T T A T T T T T A T T T T T T T T T T T A T T T A T T T T T T T T T T T T T A T T T T T A A T T A T T T T T T T A T T A T T A A A T T A A A T T T T T T T A T T T T T T T T T T A T T T T A A A T A T T T A T T T T A T T A T T T T A A T A A T T T T T T T T T T T T T T T T T A T T T T T T T T A A A T T T A T T T T A T T A T T T A T T A T T A T T T T T T T T T T A T T T A T T A A T A A A T A A T T T A T T T T T T T A A A T A T A A T T T A T T T A A T T A A T T A T T T T A T A +A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A A T T T T T A T T T T T T T A T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A A T T T T T T T T T A T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T A A T T T T T T T T T T A T T T T T T A T T T T A T T T T T T A T +C C C G G G G C G G G G G G G G G G C G G G G G G G G G C G C G C G G G G C C C G G C G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G C G G C G G C G G G G G G G G G C G G C G G G G G G C G G G G G G G G G G G G G G G G G C G G G G C G G G C G G G G G G G G G G G G C C G G G G G C G C C C G G C G G C G G G G C G C G G G G G G G G G G G G G G G G G C G G G G G G G C G G C G C G G G G G G C G G C G G G G G G G C G G C G G G G C C G C C C G G G G G G G G C C C G G C C G G G G G G G C G G G G G G G G +G G G C C C G G C G G C G G G G G C G C C G G G G G G C G G G C G G G G G G G G C C G G C C G C G C G G C C C G G C C C G C G C G C G C C G C G G G C G G G G G C C G C C C C C G C C G G G G G G G G G G C G C C G C G G C C C G G C G C C C G C G G C C G G G G C G G G C C G G C C G G G C G C G C C G G C C C G C G G G G C G G G G C G C C G G C G G G C C G C C G G C C G G C G C C G C G G C G G G C C C C G C C G G C C C C C C G C C G C G G G C C C C G G C G G C C G G C C G C G G G G C C G G G G G G G C G C G C G C G G G G G G G G G G G C G C G G G C C C C G G +T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T A T T T T T A T T T T T A A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A A T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T +A T T T T T T A T T A T A T T A T T T T T T T T T A T T A T A T A T T T T A A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T A T T T T T T T A T T T A T A T T T T T T T A T T T T T A T A T T T T A A T A A A T A A A T A T T T T A T A T T T T T A T T T A T T T T T T T T T T A T T T T T T T T T A A A T A T T A T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T A A A T T T A T A T T T T T A T T T T T T T T +C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C C C C G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C G C G C C C C C C G C C C C C C C C C C G C C C C C C C C G C C G G C C C C C C C C C C C C G C C C C C G C C C C C C C C C C C C +G G G G G C C G C G G G G C C G G G G G G G G G C G C C G G G C G G G G G G G G C G G G G G C G G G G C G G G G C C G G G C G C G G C C G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G C G G G G G G C G C G G G G G C C G C C C G C G G C G G G G G C G G G G C G G C C C G G C C C G G G C G G G G G C G C G C G C G G G C G G C G G G G G G G G G G G G G C C G G C G C G G C G G C G C G C G G G G G C G G C G G G C G G G C G G G G G C C G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G C C G G C G C C C G G G +A T T T T T T A T A A T A T T T A T T T T A T T T T T T T T A T T T T T T T A T T T A A T T T T A T A T T A T A T T T T A T T T A T T T T T T A A A T A T A T T T T T T T T T T T T T A T T T T T A T A A T T T T T T T T T T T T T T A T T T T T A T T A T T A A T T A T A T A A T T T T T T T T A T A T T T T T T T A T T T T T T T A T A A T T A T A T A T A T A T A A T T A A T A T T T T A A T A T T T T T T T T T A T T T T T T T T T T A T A A A T T T T A A T T T T T A T T T A T T T T A T T T A A T A A T T T T T T T T T T A T T T T T A T T T T T A T T T T T T T T +A T T T T T T A T A A T A T T T A T T T T A T T T T T T T T A T A T T T T T A T T T A A T T T T A T T T T A T A T T T T A T T T A T T T T T T A A A T A T A T T T T T T T T T T T T T A T T T T T A T A A T T T T T T T T T T T T T T A T T T T T A T T A A A A A T T A T A T A A T T T T T T T T A T A T T T T T T T A T T T T T T T A T A A T T A T A T A T A T A T A A T T A A T A T T T T A A T A T T T T T T T T T T T T T T T T T T T T A T A A A T T T T A A T T T T T A T T T A T T T T A T T T A A T A A T T T T T T T T T T A T T T T T A A T T T T A T T T T T T T T +G C C C C C C G C G G C G C C C G C G C C G C G C C C C C C G C C C C C C C G C C C G G C C C C G C G C C G C G C C C C G C C C G C C C C G C G G G C G G G C C C C C C C C C C C C C G G G C C G G C G G C G C C C C C C C C C G C C G C C C C C G C C G G G G G C C G C G C G G C C C C G C C C G C G C C C C C C C G C C C C C G C G C G G C G G C G G G C G C G C G G C C G G C G C C C C G G C C C G C C C C C C C C C C C C C C C G C C G C G G G C C C C G G C C G C C C C C C G C C G C C C C G G C G G G C C C C C C C C G G G C C G G C G G C C C C G C G C C C C C C +C C C C C C C C C C C C C G C G C G C G C C C C G G G G G C C G C C C C C G C C C G C C C C C C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C G C C G C C G G C G C G G G C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C G C C C C C 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T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T A A A T A T T T T T T T T T T A T T T T T T T T T T T A T A T T T T T T T A T T A T T A T T A A A T T A A T T T A T T A A T A A T A T A T T T A T T T A T T T T A T T T T T T T T A A T T T A T T T T A T T T A T A T T T T T T T T T T T T T T T T T T T T T A T +G G G C C G C G G G G G G C G C G C G C C G C G C C C G C C G G G C C C C C G G G C G G G C C C G C G C G G G G G G C C G G C G G C C G C G C G G G C G G G C C G C C C G C C G C G G G G G C C G G C G G C G C C C C C C C C C G C G G G G G C G G C G G G G G G G C G G G G G G C G G G G G G G G C G G G C G G G G G C C C C C G G G G G G G G G C G G G C G G G G G G G G G G G G C G C G G G G G C G G G G C C G G G C C G C C G G G G G G G G G G G C G C G G G G G C C G C C C G C C G C G G C G G G G G G C G C G C G C G G G G C G G G C G G G C G C G G G G G G C G C +C C C G G C G C C C C C C G C G C G C G G C G C G G G C G G C C C G G G G G C C C G C C C G G G C G C G C C C G C C G G C C G C C G G C G C G C C C G C C C G G C G G G C G G C G C C C C C G G C C G C C G C G G G G G G G G G C G C C C C C G C C G C C C C C C C G C C C C C C G C C C C C C C C G C C C G C C C C C G G G G G C C C C C C C C C G C C C G C C C C C C C C C C C C G C G C C C C C G C C C C G G C C C G G C G G C C C C C C C C C C C G C G C C C C C G G C G G G C G G C G C C G C C C C C C G C G C G C G C C C C G C C C G C C C G C G C C C C C C G C G +A A A T T A T A A A A A A T A T A T A T T A T A T T T A T T A A A T T T T T A A A T A A A T T T A T A T A A A T A A T T A A T A A T T A T T T A T A T A A A T T A T T T A T T A T A A A A T T T A A T A A T A T T T T T T T T T A T A A A A A T A A T A A A A A A A T A A A A A A T A A A T A A A A T A A A T A A A A A T T T T T T A A A A A A T A T A T A T A A A A A A A A A A A A T A T A A A A A T T A A A T T A A A T T A T T A A A A A A A A A A A T A T A A A A T T T A T T T A T T A T A A T A A A A A A T A T A T A T A A A A T T A A T A A T T A T A A A A A A T A T +T T T A T T T T T T T T T A T A T A T A A T A T A A A T T T T T T T A A A A T T T A T T T A T A T A T A T T T T T T A T T T T T T T A T T T A T T T T T T T A A T A T A T T T T A T T T T T A A T T A T T T T T T A T A T A T T T T T T T T T A T T A T T T T T T T A T T T T T T A T T T T T T T T A T T T A T T T T T A T T A A T T T T T T T T T A T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T A A T A T T T T T T T T T T T T T T A T T T T T A A T A A T T A T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T A T T T T T T A T A +G G G C C G C G G G G G G C G C G C G C C G C G C C C G C C G G G C C C C C G G G C G G G C C C G C G C G G G C G G C C G G C G G C C G C G C G G G C G G G C C G C C C G C C G C G G G G G C C G G C G G C G C C C C C C C C C G C G G G G G C G G C G G G G G G G C G G G G G G C G G G G G G G G C G G G C G G G G G C C C C C G G G G G G G G G C G G G C G G G G G G G G G G G G C G C G G G G G C G G G G C C G G G C C G C C G G G G G G G G G G G C G C G G G G G C C G C C C G C C G C G G C G G G G G G C G C G C G C G G G G C G G G C G G G C G C G G G G G G C G C +G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C C C G G G G G G G G G G G G G C G G G G G G G G C G G G G G G G G G G G G C G G G G G G C G C G G G G G G G C G G G G C G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G C G G G G G G G G G G C G G G G C C G C G G G G G G G G G G C C C G G C C G C C G G G G C G G G G G G G G +T T A T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T A A A T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T A T T A T T T T T T T T T T A A T T T A A T T A T T T T T T T T T T T T T +T T A T T A T T A T A A A T A T A T T T T A T T T T T T T T T A T T T T T T A A A T A A A T T T T T T T A A A T A A T T A A T A A T T A T A T A T A T A T A T T A T T T A T T A T A A T T A T T T T T T T T T T T T T T T T T T T T A T A A A T A A T A T A A A T A T A A T A A A T A A A A A A A A T T A A T A A A A A T T T T T A A T A T A A A A T A A T T T A T A A A A A A A A A T A T A A T A A T A A A A T T A A T T T A T T A A T A A T A A A T A T A T T A A A A T T A T T T T T T T T A A T T A A T T T T A T A T A T A T T A T A T T T T A A T A T A A T A A A T A T +C C C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G 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A A A A T T T T T A T A T A A T A A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T A A T T T A T T T A T A T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T A T T T T T T T A T T A T T T T T A T T A T T T T T T T T T T A T T A T T T T A T T A A A A T A T A T T T A A T A T A A A T A T T T T T T T T T T T T T +T T T A A T A T T T T T T A T A T A T A A T A T A A A T A A T T T A A A A A T T T A T T T A A A T A T A T T T A T T A A T T A T T A A T A T A T T T A T T T A A T A A A T A A T A T T T T T A A T T A T T A T A A A A A A A A A T A T T T T T A T T A T T T T T T T A T T T T T T A T T T T T T T T A T T T A T T T T T A A A A A T T T T T T T T T A T T T A T T T T T T T T T T T T A T A T T T T T A T T T T A A T T T A A T A A T T T T T T T T T T T A T A T T T T T A A T A A A T A A T A T T A T T T T T T A T A T A T A T T T T A T T T A T T T A T A T T T T T T A T A +C C C C C C C G C G G C G C C C C C G C C C C C C C C G C C G C G C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C G C C C C C C C C G C C C C C C C C C C G C C G C C C C G C C G G G C C C C C C C C G G C C C G G C C G C C C C C C C C C C C C C +G G G G G C G G C G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G C G G G C G C G G G C G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G C C C G C C G C G G G C G C G C C G C G G G C C G G C G C G G G C G G G G G C G G G G G G G G G G G G C G G G G G G G G C G G G G C C C G C G G G G C G G C G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G C C G G G C G G G G G G G G G G G G G G G G C G G C C C C C G G G +T T T T T T T A T A A T A T T T T T A T A A T T T T T A T T A T A T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T A T T T T T T A T T T A T T T T T A T T T T T T T T T T A T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A A T T A T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T A A T T A A T T A T T A T A T A T T T A A T A T A A A A T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A 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G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C G C C C C C C C C C C C C G C C C C G C C C C C G C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C G C C C G C C C C C C +A A A A T A T A A A A A A T A T A A A T T A T A A T T A A A A A A A T T T T A A T T A A A T A T A T A T A A A A T A T A T A A A A A T T A A T A T A T T A A T T A A A T A A A A T A A A A A T T A A T A A A A A A T A T A T A A A A A A A A A T A A T A A A A A A A T A A A T A A T T A A A A A T A T A T A T A A A T A T A A T T A A A A A T T A A T A A A T A T A A A A T T A A T A T A A T A A T A T A T A A T A T A A T T A T A A T A A T A A A A A A T A T A A A A A T T A T T A A T A A T T A T A A A A A A A A A T A A T A A A A A A A A A A A A T A T A A A T A T T A T +A T A A A T A T A A A T A A A T A A A A A T A T A A A T A T T T T A A A A T A A T T T T T A A A A A T A T T T A A A A A A A A A A A A T A A A T A T A A T T A A T T A A A A A T A T T T A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A T A A A A A T T T A A A A A A A T T A T T A A T T T T T A T A A A T T T A T A T T A T A A T A A A A T A T A A T A A A A T A A T A T A A T A T T T T A T T A A A A A T A A T A T T T T A A A T A T T T A T A A A A A A T A A A A A T T A A T A T T T T T A T T A T A A A T T A A T A A T A A T A T A A A T A T A +C G C C C C C C C G G G G C C C G C C C C G C C G C C G C C C G G C C C C C G C C C C G G C C C G C G C C C G C C C C C C C C C G C C C C C C G C G C C C G C C G G C C C C C G C G G G C C C C C C C G G C G C C C C C C C C C C C C C C C C C C G C C G G G G G C C G C G C G G C C C C C C C C G C G C C C G C G C G C C C C C C C G C G C C C G C G C G C G C G G G G G C G G G C C C C C G C C C C C C G C G G C G C C C C C G G C 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T A A A T T T A A A A A A A A A A A T A T A A A T A T A A A A A A A A A T A A A A A A A A A A T A A T T A T T A A A T A A A A A T A A A A A A T A T T A A T A A A A A T A T A A T A A A A A A T A A A T A A A A T T A A T A A T A A T T T A T T T T T T T A T A A T T T A T A T T T A A A A A A A T A A T A A T A +C G G C C C C G G G G G G C C C G C C C C G C G C C G C C G C G G C C C C C G G C C C G G C C C C C G C C C G C C G C C C C C C C C C C C C C G C C C C G G C C G G C C C C C G C G G C C C C C C C C G C C G C C C C C G C C C G C C G C C C C C G C C G C G G G C C G C G C G G C C C G C C C C G C C C G C G C G C G C C C C C C C G C G C C C G C G C G C C C C G G G G C G G G G C C C C G C C G C C C G C G G C C C C C C C C G C C C C C C C G C C C G C C G G G C C C G G C C C C C C C C G G C C G C C C G G G C G C C G C C G G G C C G C G G C C G C G C C C C C G C +G G G C C C C G G C G G G C C C G C C C C G C C C C G C C G C G G C C C C G G G C C C C G G C C C G G C C C G C C G C C C C C C G C 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T T T T T T T T T T T T T T T T A T T T T A T T T T A A T T T T A A A T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T A T T T T T A T T T A T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T A T T A T T T T T A T A T T T A A T T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T A T T T T T T T A T T T T A T T T T T T A T T T T T T T T T T T T A T T T T T T T A T T A T T T T T T T T T T T A T T T T T T T A T T A T T T T A T T A A A T T T T T T T T T T A T T T A T T T T T T A T T T T A T T T T +G C G G G G G C C C G G G C G G C G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G C G G G G C G G C C G G G G G G G G G G G G C G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G C G C G C G G G G G C G G G G C G C G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G C G G G G G G 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T A A A A A T A T A A A A A A A A A +C C C C C C C C C C C C C C C C G C C C C G C C C C G C C C C G G C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C G C C C C C C C C C C C C C C C C C G G C C C C C C C G C C C G G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C G C C C C C C G G C C G C C G C C C C C C C C C C C C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C G C C G C C C C C C C C C C C C C C C C C C C C C C C 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A A A A A +G G C G G G G G G C G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G C G C G C G G G G G C G G G G G G G G G G G G G G G G G G C G C C G G G G G C G G C G G G G G G G G G C G G G G G C G G G C G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G C G G G C G G G G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C G C C G C C C C C G C C G C C C C C C C C C C C C C C G C C G G C C C C C C G C 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T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G G G G G G G G C C G G G G G G C C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G G G C C G G G C G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G C C G G G G G G G G C C G G G C G G G G G G G G G G G G C G G G G +G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G C C G G G G C C G G G G G G G G G G G G G G G G G C C C G G G G G C G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T A T A T A A A A T A A A T A A T T A T A A T T A T A A A A A A T A T T A A T T T A A A A A A A A A T A A T A A A A A A A T A A T T A A A A A A A A A A T A T T A A T A T T T T T A A T A A T T T A A T T A T T A T T T T A A A A A A T A A A T A A A A T A T A T A A A T A A A A A A A T A T A A T A T A T A A A A A A A A A A A T A A A T T A T A A T A A T A T T A A A A A T A A T A A A A T A A A A T T A A A T T A T T T A T A A T T A T T A A A T A A A A A T A T T T A T A T A T T A T A T A A T A A T T T T A T A T A T A T T T A T T T T A T A T A T T T A A T A A T A +A A A A T A A T T A A T T A A T A A A A T T T A A T T A A A T T A T A A A A A A A A T A T T T A A A A A A A T A A T A A A T T T A T A A A T A A T A A T A A T T T T A A A T A A T T A A T T T T A A T A A A A A A A A A A T A A A A A A A A A A A T A A A T A T A A A T T T A T T A A A A T A T A A A T A A T T A A T A A A T T A A T T T A A A A A T A T A T A A T T A T A A A A A A A A T T A A T T T A A T A T A A A A A A T A T T A A A A A T A A A T T T T T A T A A T T A A T A A A A A T A T T A A T A A A A T A T A A A T T T A A A T A A T A A A A A A A T T A A A A A +C C C G C G G C C C G G G C G C C C G C C C C G G C G G G G G C C C C C G G C G G G C C G C C G G G C G G C G G G G G G G G C C C C G G G C G C C G G C G G C C G C C G C C C C C C G C G G C C C C C C C G C C G C C C C G G G G C G C G G G C G C G G G G C C G G G C C C G C C G G C G G G G G C G C G C C G G G C G G G C C G C C C C C C G C C G C C G C G C C G C G C G C C C C G G G G C G C C C G C G G G G G G G C G G C G G G C G G C G G C C G G C G G G G G C C C G G C G C C G C C C G G C G G C C C G G 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G G G G G G G G C G G C G G G G G G G G G C G C G G G G C G G G C G C G G G G C G G G G C G C G G G G G G G G G G C G G G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C C G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G C G C C G G G G G G G G C C +G C C G C C C C C G G C G C G C G C C C G G C C G C G C G G G G C C C C G G G C C G C G C C C G G G C G G C G C G C C G G C C G C G G C C C C G C G G G C G C G G C C G C C C C C G C C C G C C C G G G G G C C G G G G G G G G G C G C G G G C G G G G C C G G C G G G C G C C C C G C C G G G G C G C C C C G C G C C G C C C G C C C C G C G C G G G G C C C G C C G C G C C G G C G G G G C G G G C G C G G C C G G C C G G G G C G G G G C G G G C C G C G G C G C C G G G G C G C C G C G G C C C G G C C C C C C G C G C G C C G G C C C G C C G C C C G C G C C G C C C +T A A T A A A T A T T A T A T A T A A A T T A A T A T A T T T T A T A A T T T A A T A T A T T T T T A T T A T A T A A T T A T T T T T A A T T T T T T T A T A T T A A T T A A A A T A A A T A A A T T T T T A T T T T T T T T T T A T T T T T A T T T T A A T T A T T T A T A T T A T T A T T T T A T A A A A T A T T A T A T T T A A A A T A T A T T T T A A A T A A T A T T A T T A T T T T A T T T T T A T T A A T T A A T T T T A T T T T A T T T A A T A T T A T A A T A T T A T A A T T T T A A T A T T A A A A A T A T A T T T T T A T T T A A T A A T T A T T T T A A A +T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T T A A A A A A A A A A A A A A A T A A A A A A T T T T A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A T A A A A A A A A A A A A A A T A A A T T A A A A A A A A A T A T A A A A A A A T T T A A T T A A A A A A A A A A A A A A A A A A A T A A A A A A A A A T A A T A A A A A A T A A A A A A A A A T A A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +G G G G G G G G G G G G G G G G G C G C G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G C G G G G G G G G G G G G G G C C G G G G C C G G C G G G G G G G G G G G G G G G G G G G G G G G G G C C G C C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T A A A T T A A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T A T T T T T T T T T T T T T T T T A T T T T A T T T T T T A A T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T +A T T T T A A T T A A T A T A T A T A T A A T T A T A T T T A A T A T T A T A T A A A A T T T A A T T A T T T T T T T A T T T A T T A T A T T A T T A A T T T A A T T T T T T T T A T A T T T T T T A T T A T T A T T T T A T T A T A T A A A T A A A T T T T A T A A A T A A T T T A T T T A A A T A T A T T A T A T A A T T T A A A T T A T A A A A A A T T T A T T A A A A T A A T T A A A T A A A A A T A A T T T A T A A A T A T A T A A A A A A T T A T A A T A T T T T A A T T A T T T A A T T T A A T A A T T T A T A T A T T A T T T T A T T T T T T A T T A T A A T T +G G C G G G G G G G G G G G G G G C G C G C G C G C G G G G G C C G G G G G G G G G G G G G G G G G C G G C G C G G G G G G G G G C G G G G G G G G G C C G G G G G C G G G G G G C C G G G G G G C C G G G G G G G C G G G G G G G G G G G G G G C G G G G G C G G G C C G G G G G G G G G G G G G G C G C G G G G G G G G G C G G G G G G G G G G G G G C C G G C G G G G G G G G C G G G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G C G G G G G G G C G G G C G G G G G G C G G G G G G G +G G C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C G G C C C C C C C C C C C C G G G G C C C G C C C C C C C G G C C C C G C G C C C C C C C G C C C C C C C C C C G C G C C C C C C G G C C G C C C C C C C C C C C C C C C C C C C C C C C G G C C C C G C G C C C C C C C G G G C G G G C C C C C C C C C C C C C C C C C C C G C C C C C C C C C G C C G C C C C C C C C C C C C C C C C G C C C C G C C C C C C G G C C C C C C C C G G G C C G C C C C C C C C G C C C G C C C C +A A A A T T T A A T T T T A T T A A A A T T T A T A T T A A T T A A A A T A A A A T T A T A A A T A A A A A T A A T A A T T A T A A A A T A A A A A T T A A T T T T A A A A A A T T A A T T T T A A T A A T A A T A A A A T A A T A T A T T T A T T T A T T A T A T T T A A T A A A A A A A A T T A T A T A A T A T A T T A A A A T T A A A A T T A A A T A A A T A T A A A T A A A A A T T T A A T T T T A T T A A A T A A T T T T A T A T T A T A A A A T A T T A T A A T T T T T A A A A A T A A A A T A A A A A A A T A T A T A A A A A A A T A A A A A A A A T T A T A A A +A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T A T A T T T T T T T A T A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C G G C C C C C C C C C C G C C C G C G C G C G C C C C C C C G G G G G C C C G G C C C C C C C C G G C C C C C C C C C C C C C G G C G C C C C C C C G G C C C C C G C G G C C C G C G C C C C C C G C C C C C C C G C C C C C C G C C C C C G C C C C C C C C C C C C G C C G G C C C C G C C C C C G C G G C C C C C C C C C C C C C G C G C C C G C C C G C C G C C C C C C C C C G C C C G C C C C C G C C G G G G G C G G C C G G C C G G C C C G G C G C C C G C C C C C C C C G G C C C C G G C C C C G G G G G C G C G C G G C G G G C C G G G G C G C G C C C C C G C +C C C C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C C C C C C C C G G C C C C G C C C C C C C C C C C C C C C G C G C C C C G C C C C C G C C C C C G C C C C C C G C C C C C G C C C C C C G C C C C G C C C C C G C G C G C C C C C C C C C C G C C C C G C G G C C C C C C C C C G C C C C C C G C C C C C G C C C C C C C G C G +T T T T T T T A A T T T T T T T T T A T T T T T T T T T T A T T A A T T T A T T T T T T T A A T T A T T T T T A T T T T T T A T A T T A T A T T A A T T T A T T T T T T T A T A T T T A T T T T A A T T T T T A T T T T A T T T T A T T T T T T T T T A T T T T A T T T T T T T T A T T A T T T T A T T T T A A A T A T T A A T T T T T T T T T T T T T T A T A T T T T A T T A T T A A T T T T A T T T T T T A A T T T A T T T T T A T A T T A T A T A A T A A T A T A T T T T T T T A T T A T T A A A T A A A A T A T T T T T A T T T A T T A T T A A T A T T T T T T T A T A +A T T A A A A A A A T T T A A T T T A T A A A A A T A A A A A A A A A A T A A A A A A A T A A T A A T T T T T T A T A A T T A T A T T A A A A A A A A A T A A A A T T A A A A T A A A T T A A A A A A A A A A A A A A A A T A A T A A A A A A A A A T A A T T A T A A A T T A A A A T A A A T T A A T T A T A A A A A A A A A T T T A T T T A A T A A A A A T A A T T A T A A A A A A A A A T A A A A T A A A A A A A A T T A A T A A A A A A T A A A A A T A A T A A A A T T A A T A T A A A T A A A A A A A T T A A A T A A A A T T A A A T A A A A A A A A A A A A A A A A A +G G C G C G G G G G G C C G G G C G G C G G C G G G G C G G G G G G G G G G G G G G G G G G G C G G G C C G C G G G G G G G G G G G C C G G G G G G G G G G C G G G G G G G G G C G C G G G C C G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G C G G G G G G G G G G G G G C C G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G C G G G G G G G G C C G G G G G G G G G G G G G G G G G G G C C G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G +G G C G C G G G G C G C C C G G C G G C C C C G G G G C C G G C C C G G C G C G C G C G G G G C G G G C C C C G C G C C G G G G C G C C G G G G G G G C G G C G C G G C C C G C C C C G G G C C G G C C C C C G C C G C G C C C C G C C C C C G G C C G G G C G C C G C G C G C C G C G G G C C G G C G G G G G G G G G G G G G C C C C G C G G C G G C C G G G G G G G G C G G G G G C G G C G G C G G G G G G C G G C G C G C G G G C G G G G G G G G C C G G G G G G G G G C G G C G G C G G C C C G C G G G G G C G C G G G G G G C G G G G C G G C C G G C G G G C G G G G +T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T A A A T T A T A T T T T T T T A A A A T T T T A T A T A T T T T T A T T T T T T T T T T A T A T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T A T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A A T T T T T T A T T T T +A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A T A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A T A A A A A A T T T A A T A T A A A A A A A T T T T A A A A T A T A T A A A A A T A A A A A A A A A A T A T A A A A A A A A A T A A A A T A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A T A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A T T A A A A A A T A A A A +G C G G G G G G G G G G G G G G G G G G G C G G G G G G C G G C C G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C C C G G C G C G G G G G G G C C C C G G G G C G C G C G G G G G C G G G G G G G G G G C G C G G G C G G G G G C G G G G C G G G C G C G G G C G G G G G C G G G G G G G G G G G G G G C G G C G G G G G C G G G C G G G G G G G G G G C G G G G C G C G C G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G C C C G G G G G G C G G G G +G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G G C C C C C C C C G C G C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C +T T A A A T A A A A T A A A A A A T T A A T A T A T A A T A A T A T T T A A T A A T A T A A A A T A T A A A A T A A A A A A A A A T A A A A A T A T A T T A A T A T T T T A A T A T A A T T A A A T T T T A T A A T A A A T A A A T A T A A A T A A A A A A T A T A A A A A A A A A A A A A A A A T A A A T A A A T A T A A A T A A A A A A T A A T T A A A A A A A A T A T T T T T A T A A A T T A A A T A T A A A A T A T A T A A A A A T A A T A T T A A A A A A A A A T A A A A A A T A A A T A A A A A A A A A A A A A T T A T T T T A T A A A T T T A A T T T A T A A T A +T T A T A T T A A A T A A T T A A T T A A T A T T T T A T T T T A T T T A T T A T T A T A A A A T T T A A T A T A A T A T T A A A T A T T A T T A T T T T T A T A T T T T T T T A T A A T T A A T T T T T T T T T T A A A T A A A T A T A A A T A A A T T A T A T A A A A A T T T T T T T A A T T T A A T T A T T T A T T T A T A A A A T A T T A T T T A T A T A A A T T T T T T T T T T T A T T A A A T A T T A T A T A T A T A T A A T T T A T A T T A A A T A A A T A T A A T A A T T A T A T A A T A A T T T T A T A T T T T T T T T T T T A T T T T T T T T T A T A T T T +G G C C C C C C C C G C C C C C C G C C C G G G C G C C G C C G C C C C C C G C C C C G C C C C G G G C C C C G C C C C C C C C C G C C C C G G C C C G G C G G C G G G C C C G G G C C G G C C C C G G G C G C C G C C C G C C G G C G C C C C C C C C C C G G G C C C C C C C C C G C C C C C C C C C C G C C C G C C C C C G C C C C G C C C C G G C C C C C C C C G C G C G G G C G C C C C G C C C G C G C C C C G C G C G C C C C C G C C G C G G C C C C C C C C C G C C C C C C C C C C G G C C C C C C C C C C C C G C C G G G C C G C C C C C G C C G G G G G C C C C +G G C C C C G C C C G C C G G C C G C C C G C G G G C C G C C G G C C C C C G C G C C G C C C C G C G C C C C G C C G C C C C C C G C G G C G G C C C G G C C G C G G G C G C G C G C C G G C C C C G G G C G C C G C G C G C C C C C G C C C C C C C C C C G C G C C C G C G G G C G C C C C C G C C G G G C C C G C C C C C G C C G C G C C C C G G G C C G C C G C G C G C G G G C G G C C C C C C C G C G C C C C G G G C G G C C C C G C C G C G C C C C C C C C C C G C C G C C C C C C C G C C C C C C C C C C C C C G C C G G G C C G C C C C C G C G G G G C G G C C C +A A A T A A T A A A A A A A T A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T T A A A A A A A T A A A A A A A A A A T A A A A T A A A A A A A A A A A A A A A A A A T A T A A A A A T A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A T T A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A +A A T A A A A T T T A A A A A T T A A T T A A A A A A T A A A A A A A A T A A T A A T A T T T T A A A T T A T A T T A T A A T T T A T A A T A A T A A A A A A A T A A A A A A A A A T A A A A A A T A A A A A A A A T A T A T T T A T A T T T A T T T A A A A T A T T T T A A A A A A A A T A A A A T T A A T A A A T A A A T A T T A T A A A A T A A A T T T A T T T A A A A A A A A A A A T A A T T A A T A A T A T A A A T A A A T T A A A T A T A A T T T A A T T A A A A T A T T A A T A A A T T A T T A A A A T A T A A A A A A A A A A A T A A A A A A A A A T A A A A A +G G C G G G C C C C G G G G C C C G G C C C G G G G G C G G G C G G G G C G C C G G C G G C C G C G G G C G C G G C G C G G C C C G G G C C G C C G C C G G G G C G G C G G G C G C C G G G G G G C C G G G G G G G C G C G C C C G C G C C C G C C C G G G G C C C C C G G G G G G C C G C C G G G G G C G C G G G C G G G C G C G G C G G G G C G G G C G G G C G G G G C G G C G G G C G C G G C C G G C G G C G C G G G C G C G C C G G G C G C G G C C C G G C C G G G G C G C C G G C G G G C C G C C G G G G C G C G G G G G G C G G G G C G G G C G G C G G C G G G G G +G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G G C C C C G C C C G C C C G C G G G G C C C C C G C C G C C C C G C C C C C C C C C G C C C C C G G C C C C G C C G C C C C C C G C C G C C C C C C C C C C C C G G C C C C C C C C C G G C C G G C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C C C C G C C C C C C C C C G G G C C C C C C G C 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T T A T T T T T T T T T T A T T T T T T T A A A A T T A A A A A T T A T A T T A A A A A T T T T T T A T T A T T T T A T T T A A T T T T T T T T T T T T T T T T T A T T T T T T T T T T A A T A T T T T T T T T T T T A T T T T T A A A T T T T A T T T A A T T T T A T T T A T A T A T T A T T T T T T T T T T T A A A T A T A T T T A A T T A A T T A T T T A T T T T T T A A T A +T T T T T A T T T T T T T T T T T T T T T T T A T A T T T T T T T T T A T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T A A T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T A T T T T A T +G G G G G G G G G G G G G G G G G C G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G C G G G G G G +G G G G G G G G G G G G G C G G G G G G G G C C G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G C G C G G G G G C G C G G G G G G G G C G G G C G G G G C G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G C G G C C G G G G G G G G G C G G G G G G G G G G G G C C G G G G G G G G C C G G G C C G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G +T A T A A T T T T T A A A A T T A T A T T T A A A A A T T A A T A A T A A A T A A T T T T T T A T A A T T A A A T T A T A A T T T A A A A T A T T T T T A A A A T A T T A A A A A T T A A T A A A T T A A T T A T A T A A A T T T A A A A A A A T A A A A A T T A T A T A T T A A T T T A A T A A A A A T T T A T T T T T A T A A A A T A A T A T A A T T A A A T A T T A T T A T T T T T T T A T T T A T T T A T A T T T T T A T A T T T A T T T T A A T A T A A T A A A T A T A T T T T T A A A T T A T T A T T A T A A A T T A T T T A A T A T A T A T A T T T A T T A A T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A 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G G G G G G G C C C C C C C C G C C C C C G C C C G C C C C C G G C C C C G C G G G G G C C G C G C C C C C G G C C G G G C C G C C C C C G C C G C G C C G G C G C C G C G C C C G G C C G G C C G C G G C G C G G C C C G G G C G G C G G C G C G C C G C C C C C C C C C C C C C G G C G C G C C G G G +T T T A A T T T T T T A A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T A A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T A T T T T A T T A T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T +T A A A A A A A A T A A A A A A T T T A T A A A T A A T T A T A A A A A A T A A A T A T A A A A T T A A A T A A A A T A A A A A A A A T A A A A A A A A A T A T T A T A A T T A A A A A A T A A A A A A A A A A A A A A A A A A T T A A A A A A T A A T T A T A A A A T A A A A A A A A A A A A A A A T A A T A A T A A A T A A A A A T A T A A T A T T A A A A A A A T A A A A A T A A A A A A A T T A A T T A T T A T A T T T A A T T T T A T A T A A T A T A A A A A A A A T A A A A A A A A T T T A T A A A A T T T A T T A A T T A T T T A T T A T A A A A T A T A A A A A +C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G C G G G G G G G C G G G G G C G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G +G C C G G G G C G G G G G G G G G C G G G G G G G G G G G G G C G G C G G G C G G C G G C G C G G G G C C G G G G G G G G G C C C G G G G C G C C G C G G G G G G G G C G G G G G C G G G G G G G C G G G G C C G G G G G G C C G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G G G C G G G C G G G G G C G C G G G G G G G G G G G G G G C G G G G G G G G G C G G G G C G G C G G G G G G G G G G G G G G G G G G G C C C G G C G G G G G G G G C G G G G G G G G +A T T A A A A A A T A A A A T T T A A A T A T T T A A A A T A A A A A A A A T A A A A A A A A A T A A A A A A A A T T T A A A A T A A A A A T A A A A T T A A T A A A A A A T A A A T A A A A A A A A T T T T A T T A A T T A A T A T A A A A A T A A A T A T T A A A T A A A A A A T A T A T A A A A A T T A A A T T A A A A A A A A T A A A A A A A A A A A T T A A A T A T A A A A T A A A A A A A T A T T A T T A T A A A A A A A T T T T A A T T T T A A A A A T A A T A T A T A T A A A T T A T A T A A T T T T T A T T A A A A A A T A A A T A T T A A A A T T T A A A A +A A A A A A A T A A A A A A T A T A T A T A A A T A A A A T A T A T T A A A T A A A A A A A T A T A A T T A T A A T T T A A T T A A A A A T A A T A T T A A A T A A A T A T A A A T T A A A A A A A T A A T T A T A T A A A T T A A A A A A A A A A A A T A A A T A A A A A A A A A A A T A A A A A A A T A A A A T A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A T A A A T A A A T A A A A T T A A T A A A A A A A A A A T T A A A T T A A A A A A A T A A T A A A A T A A T A A T A A A A A A A A T A T A T T A A A A A T T A A A T A T A A A T A A A A A A A A +G G G G G G G G G G G G G G G G G C G G G G G G G C G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G C G G C G G G G G C G G G G G G G G G G G G G C G G C G G G G G G G G G C G G G C G C G G G G G G G C C G G C G G G G C G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C C G G G G G G G G C C G G G C G G G G G G G G G G G G G C G G G +C C C C C G C C C C G G C C C C C G C G C C C C G G C G C C C C C C C C C G C G G C C C C C C C C G C C C G G G C C C C C C C C C G C G G C C C C G C C C G G C C G C C G C G C C C C G C C C C C G C G G C C G C G C C G G C C G C C C C C C C C C C G C C G C C C C C G G C C C G C C C G C C C C G C C G C C C C C G G C C G C C C G G G G G C C C C C G G C C G C C C C G G C C G C C C C C C C C G G C C C C C C G C C C G C G C C C C G C C C C C C C C C C C C C C G C C C C C G C C C G C C C C C C C G G C C C C C C C C G G C C C G C C C G C C G C C C C C C G C C C +A A T T T T T T A T T T T T T T T T T T T T A T T T T T A T T T T T T A T T T A T A A A T T T T A T T T T T T T T T T T A A T T A T T T T T T T T T T T T T A T T T A T T T A T A T T A A A A A T T T A A T T T T A T T T T T T T A T A T T A T T T T T A A T T T T T T A A T T T A A A A A T A A T A T T T T T T A T T A T T T T T A A T T A T A T A A A T A T T A T A T T T T T A A A T A T A T T A T T T A T T A T T T A T T A T T T A T T T A A T T T T T T A A A T A T A T A T T T A T T T A T T T T A T T T A T A T A A A T A A T T A A T T A T T A A T T A T T T A A T A +A A A A A T A A A A T T A A T A A A A T A A A T A A A A A A A A A T T A A A A A T A A A A A A A A T A A A A T T A A A A A A A A A T A T A A T A A T A A T A A A A T A A T T A A A A A A A A A A A T A A A A A T A A A A T A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A T A A A A A A A A A T A A A A A A A A T T A T A A A A A A A T A A A A T A A T A A A A A A A A A A A T T A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A T A A A A A A +G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G C C G G G G C C G G G G G G G G C G G G C C C G G G G G G G G C C G C G G C G G C G G G G G G G G G G C C C G G G G C G G G G G C G C C G G C G C G G C G G G G G G G G G G G G G G G C G G G C G G G C C G C G C G G G C G G G C C G G C G G G C G C C G G G G G G C C C C C G G G G G G G C G C G G C G G C G G C C G G G G G G G C C G C G G C G G G G G G G C G G C G G G G C C G G G G G G G C G G C G G G G G G G G G C C G G G G G G G G C G C G C C G G C C G G C C G G C C G C C C G G G G G C G G G +C C C C C G C C C C C C C C C C C C C C C C C C G G C G C C C C C C G C C C C G G C C C C C C C C G C C C G G G C C C C C C C C G C C C G C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C G C C C C C C C C C C C C C C C C G C C G G C C C C C C C C C G C C C C C C C C G C C G C C C C G C C C C C C C G C C G C C C C C C C C C C C G G C C C C G C G C C C C C G C C C C C C G C C C C C C C G G G C G G G C G C C C C C C G C C C C C G C C C G C G C G C C C G G C G G G C C G G C C C C C C C C C C G C C +A T A T T A T T T T A A A A A A T A T A A A T T T A A A A T A A T A T A T T T A A A A A A A A T T A T A T A A A A A T A T A A A T A T T T T A T A A A A T T T A A A A T T A A T A T A A T A A A A A T T A A T A T A A T T A T A A T T A A T A A A T T T A T A A A T T T A A T A T T A T A A A A A T A A A A A T T A T A A T A A A T T A A A A A A T T A A A A A A A A A T T A T T A T A A T T T A T A T A A A T A A A A A A A A T A T A A A T T T A A T A T T T A T T T T T T T T T T T A A T T A A A T T T T A A A A A A A A A T T T T T A T T T T T A A T T T A T T A A A T A +T A T A A A A A A A A A T A A A A T A A A A T T A T A T T A A A A A A A A A A A A A A T T A A A A A A A A A T A A A A A A A A A T T A A T A T A A A A A T A T A A A T A A A T A T A A T A T T T A T A T T A A T A T A A A A A A T A A T A A A A A A A A A A A A T A A A A A A A A A A A T A A T T A A A A T A A A T A A A A A A A A A T A T A A T A A T A A A T A A A T T A T A A T A T A A A A A A T T A A T A A A A A T T A A A A A A T A A A T T T A A A A A T A A A A A A A A A A A A A A T T A A A A T A A A A A A A A T A A T T A A T T A A A T T A A T A T T A A T T A A +G G C C G G C C G C C C C C C C C C C C C C G G G G C G G C C C G G C C C C C G G C G G C C C G C G G C C G C G G C C C C C C C C C G G C C G C C G C C G C G G C C G C C G G C G C C G G G G G C C C C C C G G C C G C C G C C C C C G C C C C C C C C C G G C C C C C G G C G C G G C G G C C C G G C C G C G C G C G G C C G C G G G G C G G G C C G G G G G C G C G G C C G C G C G C G C C C C G G G C G G C C C C G G C C G G C C G G G C C G G C C C C G G C G G G G G C G C C G C C G G G C C G C C G G G C C C C C G C G G G C C C G G C C C C G G C C G G G C G C C C +G G G C G G C C G C C C G C C C C G C C C C G G G G C G G C C C G G C C C C C G G C G G G C G G C G G C C G C G G C C C C C C C G G G G G C C C C G C C G C G G C C G C G G G C G C C G G G G G C G C G G C G G C G G C G G C C G C C G C C C C C C C C G G G C G C C C G G C G C G G C G G C G G G G C C G C G C G C G G C G G C G G G G G G G G C C G G G G G C G C G G C G G C G C G C G C C C C G C G C G G C G C C G G C C G G C C G G G C C G G C C C C G G C G G G G G C G C C G C C G C G C C G C C G G G G C G G G G C G G G C G G G G C G G G G G G C G G G G G G C C +A A A T A A T T T T T T A T A T T A T T A T A A A T T A A T T T A A T T T T T T A T T A A T T A T A A T T A T A A T T T T T T T T A A A A T A T T A T A A T T A T T A T T A A T T T T A A A T T T A T A A T A T T A A T T T T T A T T A T T T T T T T T A T A T A T T T T T T T T T A T T T T A A A T T T A T A T A T A T T T A T A T A A T A A A T T A T A T A T T T A A T A A T A T T T A T T T T T T A T A A T A T T A T T T A A T T A A A T T A T T T T T A A T A T A A A T A T T A T T A T A T T A T T A A A A T A T A A T A A A T A A A A T A A A T T A T A A A T A A T T +T A A T A A T T T T T T A A T T T T T T A T A A A A A T T T T A A A T A T T T T A T T A T T T A T A A T T A T A A T T T T T T T T A A A A T T T T A T A A T A A T T T T A A T T A T T T A A A A T T T A A T A T T A A T A A T T A T T T T T A T T T T T A T T T T T T T T T A A T A A T A T T A T A T T T T T A T A T A A T T T T A T T A A A A T T T A T T T A T T T T T T T A T T T A T A T T T T A A A T A A T A T A T A T T A A T T A A T T T A T T T T T A A T A T A A A T A T T T T T A A A T T A T T A T T A T A T A A T A T T T A T T A T A A T A T T T A A A T A T T T +C G G G G G G G C G G G G G C G G C G G G G G G G G G C C G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G C G G G G C G G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G G G C C G C G G G C G G G G G G G G C G G G G C G G C G G G G G G G G G C G G C C G G G G C G G G C G C G G C G C C G C G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G C G G G G G G G C G G G G G G G G G G G C C G G G G G G G G C C G G G C G G G G G G G C G G G G G G G G G +C G G G G G G G C G G G G G C G G C G G G G G G G G G C C G G G G G G G G G G C G G C G G G G G G G G G G G G G G C C G G G G G G G G G G G C G G G G G G G G G G G C G G G C G G G C C G G G G G C G G C G G G G C G G G G G G G G G C G G G G G G G G G C C G C G G G C G G G G G G G G C G G G G C G G C G G G G G G G G G C G G C C G G G G C G G G C G C G G C G C C G C G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G C G G G G G G G C G G G G G G G G G G G C C G G G G G G G G C C G G G C G G G G G G G C G G G G G G G G G +T T T T T T T T A T T T T T T A T T T T T T T T T T T A A T T T T A T T T A A A T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T A A T T T T T A T T A T T A A T A A A T A T T A T T A A T T T T T A A A A A A A A T A A A T A A T A A A T T T T T T T A A T T T T A T A A T T A A T T T T T A T T A T T A T T A T T T A A A A T A T A A T T T T A T T T T T T T T T T T T A T T A T T T T T T T T T T A T T T T A A T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T A T A T A A T T A A A A T A T T A T T A T T A T T T T T T A T +T A A A A A A A T A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A T A A T T A A A A A A A A A A A A A T T A A A A A A T A A T A A A A A A A A A A A A A T A T A A A T A A T A A T T A T A A A T A A T A A A A A A A A A A T A A A A A A A A T T A A T A A A T A A A A A A A T T A A A A T A A A A A A T A A A A A T A A T A A A A A T A A T T T T A A T A T A A A A A T A A A A A A A A A A A A T A A T A A A A A A A A A A T A A A A T T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A T A T T A A T T A T A T A A T A A T A A A A A A A A A A A +G C C G C C C G G G G G G C G G G G G G C G C C C C C G G C G C C G G C G G G G C G G G G G G C G C C G G C G C C G G G G G G G G G C C G G G G G C G C C G C C G G G G G C G G G G G G C C G G G G G G G G C C G G C G G C G G C G G G G G G G G G G G G G G G G G G G G G C C G C C G G G G G G C G C G G G C G G G C C G G G G C G G C G C C G G G G G G G G G G G G G G G C G G G G G C G G G G C C C G G C G G G C C C G G C C G G G G G G G G G G G G G C C G C G C C C G C G G G G G C C G G G C G G C G G G G G G G G G C G G G G G G C G G C G G G G G C C C G C G G G +G C C C C C C C G C C C C C C C C G C C C C C C C C C G G C C C C G C C C C C G C C G G C C C C C C C C C C C C C C C C C C C C C G C C G C C C C C C C C C C C C C G C G C G C G C C G C C G G C G C C C C C C C C C C G C C C C C C G C C C C C C C C G G C C G C C C G C C C C C C C G G C C C C G C C G C C C G C C C C C G C C G C C G C C G C C G G G G C C G C G G C C C C G C C C C C C C C C C C C G C C G C C C C C C C C C C G G C C C G G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C G C G G C C G G C G C G C C G C C G C C C C C C C C C C C +T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A 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G G G G G G C G C C G C G G C G G C G C C G G G G C C G G G G G G C C G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G C G G G G G G G G G C G G C G G C G G G G G C G G G G G G G C C G G G G G C C C G G C G G G C C C G G G G G G G G C C G G G C G G G G G G C C G G G G G G G G C G G G G C G G G G G G G G C G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G C G G G C G G G C G G G G G C C G G C G G G +C G G C C G G C G G G G C C G G C C G C C G G G G G G C C C G G G G G C G G G G G G G G G C G C G G C G G G C G C G G G G G C C G G C G G C C G C G C G G G G G C G C G C G C G G G G G G G G G C C G C G C G C C G G G G G C C G G G C G G G G G G G G C G G G C G G G G G C G G C G G C G C G G C G G G C G C G C G G G G G C G C G G G G G G C G G G G G G C G G C C C C G G C C G G C C G G G G C G G G C C G C G C G C G G G G G G C G G G C C G G G G G C G C G G G G G G G G C G G C C G C G G C G C C G C C G C G C C G G C G G C G G C G C G G C G C G G G G C G G G G +A T T T T A T T A A A A T T T A T T A T A A T T T T A T T T A A T T A T A A T T T A A T A T A T T T T A A T T A T A A A A A T T A T T A T T T A T T T A T A T T A A T A T A T A T A A T T T T T A T A T A T A T T A T A T T T T A A A T A A A A A A A A T T T A T A A A T A T T A T A A T T T A A T A T A T A T A T A A A A A T T T A T T T A T T T A T T A T T A T T T T T T T T T A T T T A A T A T T A A T T A T A T T T A A A T A A T T T A T T T A A A A T T T T T T A T A T A T T A T T T T A A T A T T T T T A T A T T A T T T T T A T T A T T A T A T T T T T T T A A A +T A A T A T A T T T T T T T A T T T T T T T A A A A T T A A T T A A T T T T T A A T T T T T T A T A A T T A T T A T T T T T T T T A A T A T T T T T T T A T A A T T A T T T A T A T T A A A A A T A T T T T T A T T A T T A T T T T T A T T T T T T T T A A T T A T T T T T T T T T T T A A T T T A T T T T T A T A T T T T T A A A T A A A T A A A T T T T A T T T T A T T A A T A T A T A T T A T T A T T A A T A T T A A T T T T T T A A T T T A A T T T T A T T A A T T T T T T T T T T T T A T T T T T T T T A T A T A A T T A T T A T T T T A A T A T T T A A T T A T T T +C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C C C C C C G C C C G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C G C C C C C C C C C C C C C G C C C C C C G C C C C G C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C G G C C C C G C C C G C C C C G C C C G C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C +C C G C G C G C C C C C G C C C C G C C C C C C G G C G C G C C C G C C C C G G G C C G G C C G G G G C C G C C G C C C C C C C C G G C G C G C C C C C C C G C C C C C C C C C C C C C C C G G C G C G C G C G G C C C G G C C C C C C C C C C C C C C C G G C G C C C G C C G C G C C C G C C C G C G C G C C C C C C C C C G G G C C C C C G C G C G G C G G C G G C G C C G C C C C C C G C G C G G C C C G C C C C G C C C C G C C C G G C C C G C G C C G G C G G G C G C G C C G C C C G C C C C C C C G G C C C G C C C G G G G C C G C C C G C C C G G C C C C C C C C +A A A A A A A A A A A A A A T A A A A A A A T T A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A T A A T A A T A A A T A T A A T A T A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A A A A A A A A A T A A T A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A T A A A +A A T A T A T A A A A A T A A A A T A A A A A A T T A T A T A A A T A T A A T T T A A T T A A T T T T A A T A A T A A A A A A A A T T A T A T A A T A A A A T A A A A A A A A A A A A A T A T T A T A T A T A T T A A A T T A A A A A A A A A A A A A A T T T A T A A A T A T T A T A A T T A A A T A T A T A A A T A A A A A T T T A T T A A T A T A T T A T A A T T A T A A T A A A T A T T A T A T T A A T T A T A T T T A A A T A A T T T A A T T A T A A T T A T T T A T A T A A T A A A T T A A A A A A T T T A T T T T A T T T T T A T A A T T A T A T T A A T A A A A A +C C G G G C G G C C C C G C G G G G C G C C G G G G C G G G G C G G C C C C C G G C C G G G C G G G G C C G G G G G C C C C G G C C G C G G G C G C G C G C G G C C G G G C G C G G C G G G C C C G G G C G G G G C G C C G G G G C C G C C C C C C C C G G G C G C C C G C C G C G G C G C G C C G C G C G C G C G C C C C C G G G C C C G C G G G C G G C G C C G G G G C G G C G C G G C G C G C G G G C G G C G C C G C C C C G C C G G G C G G C C G C C G G G C G G G G C G C G G C G C G C C C C C G C G G G C G G G G C G G G G G C G C C G G C G C G G G G G C G C C C +C G G G G C G G C C C C G C G G G G C G C C G G G G C G C G G C G G C C C C C G G C C C G G C G G G G C C G G G G G C C C C G G C C G C G G G C G C G C G C G G C C C G G C G C G G C C G G C C C G G C C C G G C C G C G G G G G C C C C C C C C C C C G G C C C C C C G C C G C G G C G C G C C G C G C G C C C G C C C C C G G G C G C G C G C G C C G C G G C G G C G C G G C C C G G C G C G C G G G C G G C G C C G C C C C G C C G G C C G G C C G C C G G G C G G G G C G C G C C G C G C C C C C G C C C G C G G G G C G G G G G C G C C G G C G C G G G G G C G C C C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T A T A T T A T T T T T T T T T T T T T T T T T T T T T A T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C C G C G C C G C C C C C C C C C C C C C C C C C C C C C G C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C G C C C C 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T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T A T T T T A T T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T A T T T T T T T T T T T T T T T T T +T T T T T T T T A T T T T A T T T T A T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T A T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T +G C C G G G C G G G G G G G C G G G G G G G C C G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G C G G G G G G C G C G G G G C G G G G G C G C G G C G C G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G C G G C G G C G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G C C G G G G G G +C G G C C C G C C C C C C C G C C C C C C C G G C C C C G C C C G C C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C G C C G C C C G C G C C C C G C C C C C G C G C C G C G C G G C C C C C G C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C G C C C G C C C C C C C G C C C G C C C C G C C G G C G G C G C G C C G C C G C C C G G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C G C G C C C G C C C G C C C C C G G C C C C C C +T T A A A A A T T T T T A T A T T T T T A A A T T A T T A A A T A T A T T T T T T A T T A T T A A A A T T A T T A A T T T T T T T T A T T T A A T T T A A T T A A A A A A T T T A A T A T A T T A A T A T A T T A T A T A A T T T T T A T T T T A T T T A A T A T T T A A T T A T A T T T T T T T A T A T T A A T T A T T T T A T A T A T A A A A T A T A T A A T A A A T T T T T A T T T A A A A T T A A T T A T A T A T T T A A T T A T T T A T T T T A T A A A T T A A T A T A T T T A T T T A T T T T T T T T A T A A A T A A A A T A T A T T A A T A T T T A A T T A T T A +A T T T T T T T A A A A T A T A T T A T T T T T A T T T T T T T T A T T A A A A A T A T T A A T T T T A A T T A T T A A A A A A A T T T A T T T A T T T T A T T T T T T T T T A T T A T A T A A T T A T A T A A T A T A T T A A A A A T A A A A T A A A T T T T T A A T T A T T A T A T T A T A A T T T A T A T A A T T T A A T T T A T T T T T T T T T T A T T T T T T T A A A A T A A T T T T T A T T A A A T A T A T A A A A T T A A A A T T T A A A T A A T T T A T T A T A T T A T T A A T T A A A A T A T T T A T T T A T T T T A T A T A A T T A T A T A T T T A T A A T +C C G C G G G C C C C C C C G C C C C C G G G C C G C C C G G C G C G C C C C C C G C C C C C G G G G C C G C C G G C C C C C C C C G C C C G C C C C G G C C G G G C G C C C C G G C C C G C C G G C G C G C C G C G C C G C C C C C C C C C C G C C C C G C G C C C G G C C C C C C C G C C C C G C G C C C C C C G C C C C C C G C C C C G G C C G C G C G C C G C C C C C C C C C C C G G G G C C G C C C G C C C C C C C C C C C C C C C G C C C C G C C G C C C G C C C C C C C C G C C C G C C C C C C C C C C C G C C G C G C C C C C C C C G C C C C C G G C C C C C G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T A T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A T T T T T T T A A A A T A T T T T A T T T T T A T T T A T T T T A T T A A A T A T A A A A A T T T T A A T T A T T A A A A A A A T T T A T T T A T T T T A T T T T A T A T A A T T A T T T A A T T A T A T A A T A T A T T A A A A A A A A A A T A A A T T T T T A A T T A T T A T A T T A T A A T T T A T A A A T T T T A A A T T A A T T T T A T T A T A T T T T A A T A T A A A A T T T T T T A T T A A T T T T A T A A A A A T A A T T T T T T A A T A A T A T A T A A A A A T A T T A A T T A T A A T A T T T A T T T T T A T A T T A A A A T T A A A T T T T T A A A A T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G C G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +C C C C G G C C C C C C C C C C C C C C G G C C C C C C C G G C C C G C C C C C C G C C C C C G G G G C C G C G G C C C C C C C C C G C C C G C C C C G C C C C G G C G C C C C C G C C C C C C G G G C C C G C C C C C C C C C G C C C C C C C G C C C C G C G C C C G C C C C C C C C G C C C C C C C C C C C C C G C C C C C C G C C C C G G C C G C G C C C C C C C C C C C C C C C C C C G G C C G G C C G G C C C C C C C C C C C C C C C C C C C C C C G C C C G C G C C C C C C G C C C C C G C C C C C C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C C G +A A T T A A A A A A A A A A T T A T A A A A T A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A T A A T T T A A A A A T A T A A T A T A A T A A A A A A A A A A A A A A T A A A A A A A T A A A A A A A A A A A A A A T A T A A A T A A A A A A A A A T A T A A A A A A A A T T A T T A A A A A A A A T A T T A A A A A A A T A A T A A A A A A T A A A T A A T A T A A T A A A T A A A T A T A T A A A A A A A T A A A A A A A A T A T T T T A A A A A T A A A A T T A A A A A T T A A A A A A +A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A T A T A A A A A A A A A A A A A A T A A T A A A A A A A T A A A A A T A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A +C G G C G C G G C C C C G C G C G G C G C C G C G G G C C G G G G C G G C C C C G G C G C C C G G G G C C G G C G G C C C C C C C C G G C G C G C G G C G C C G C C C G G G G C G G C C C G C C C G C G C G C C G C G C C G C C C C C C C C C C C C C C C G C C C C C C G C G G C G G G G C G C C C G G C C C C C C C G G C C G G C C G C C C G C C G G G C G C G G C C C C G G C C C C G G G G G C C G C C C G G C C G C C C C G G C C C C C G G C C C G C C G G G C G G C G C G G C C G C C C C C G C C G C C C C C C G C C G G G G C C C G C C C G C G C C C G G G C G C C G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T A T A T A T T T T T T T T T T A T T T A T T T T T T T T T T A T T T A T A T T T T T T T T T T T T A T T T T T T T T T T T T T A A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T A T T T T T T T T +A A T T T A A T A A A A T A T A T A A T A A A T A T T A A T A T A A T T A A A A A A A T T A A T A A T A A A T A T A A A A A A A A T T T A T A T A A T A A A T T A A A A A T A A A A A T A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A T T T A T A A A A A A T A A A T A A T A A A T A A A A A A A A T T A A A T A A T A T A A A A A T A A A T T A T A A A A A A A A A T A T A T A T T A A A T T T A T A A A A A T A A A A T T T A A A T A A T A T A T A A A A A T A T A A A T A A T A A T A T T T A T T T A A A T A A T A A A A T T A A A A A A A T A A A A A +G G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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C C C C C C C C C C C C C C C G G C G C C G C G C C C C C C C C C C C C C C G G C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C G G C C C G C C C C G C C G C C C C C G C C C G C C G C C C C C C C C C C C C C C C C C C C G C C C G C C C G C C C C C G G C C G C C C C G G C C G C C C C C C C C C G C G C C C C G C C C C C G G G C C C C C G G C C G C C C C C G C C C C C C G C G C C C C C C C C C C C C G C C C C C C C C G C C C G C C C C C C C G C C C C C C C C C C C G G G C G C G C C G G G G G C G C C G C C C C C G C G C C C G C C +C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C G C C C C C G C G G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C G C G C C C C G C C C G C C C C C C C C C 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T T T T A T T T A T A T T A T T T A T T A T T A T T T A T T T T T T T T A A A A T T T T T T T T A T A T T T T T T T T T T A A T T T T A T T T T T T T A A T T T T T T T A A T A T A T T T T T A T T T T A T T A A T T A T T T T T T A A A T T T T A T A T A A T T T A T T T T A A T T T T T A T T T A T T T T T T T A T T A T T A T A T T A T A A T A T T T A A T T T A T T T T T T A T T T A T A T A T T T T T T A T T A A T T T T T T T T T T T A T T T T T A T A T T A T A T T T A T T T A A A T +C G G C G G C G G G C G G G C G G G G C C G G C C C G G C G C G G G C G G G G G C C G G C G G G G C G G G G G G G G G G G G C C C G G G G C G G G G G G G G C C C C C C G G G C G C C C C G G G G C G G G G G G G G G G G G G G C G G G G G G G C G G G C G C G C G G C C G G G G G G C G G G G G G G C C G C C G G G G G G G G G G G G G C G C G G C G G G G C C G G G G G C C G G C G C G C C G G C G C G G C G C C G G G G C G G G C G G G C G G C G C G C C G G G C G G G G G G G G C G C G C G G G G G G G G C G C C C C G C C 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T T T T T T T A A T T T T A T T T A T T T T A T A T T T T T T T T T A T T T A T T T A T T T A T A T A A T A T T T T T T T A T T T T A T T T A T A T A T T T T T T T T +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T +C G G C G G C C G G G G G G G G G C G G G G G C C C C G C G G C C G C G G G G C C G G G C G C G G C G G G G G G G C C G G G G G G G C C G G G G G C G G G G C C G C C C G C C C C G G C C G G G C C C G C C G G C C C G C G C C C G G G G G G G C G G G C G C C C G G C G C G G 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A T T T T T T T T T T T T T T T T T T T T T T T T A T A T T A T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T A T T T T A A T T T A T T T T T A T A T T T T A T T T T T A T T T A T T T T T T T A T T T T T T T T A T A T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T +A A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T T A A A T A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A T A A A A A A T A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A A A A T A A A A A T A A A A A A A A A A A A A T A A A A A A A A T A A A A A A +C C G G C C C C G C C C C G 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A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G C G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G C G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T A T T T A T T T T A T T T T T T T T T T T T T A T T T T A A T T T T T T A T T T T T A A T T T T T T T T T T A T T T T T T T T A A T T T T T A T T T T T A T T T T T A A T A T T A A T T T A A T T T T T T T T A T A T T T T T T T T T T T T T T T A T T T A T T T A A T T T T T T T T T T T T T A T T T T T T T A A T T T A T T A A A T T T T T T T T A A A T T T T A A T T T T T A T T T T T A T T T T T A A T T T T A T A A T T T T A T T T T T T T T T T A T T A T A T A A T A T T A T A T A T T T T A A A T A T A T T T A A A A T A T T A T T T T A A T T A T T A T T +A A A A A A A A T T A A T A A T T A T A A A A A A A A A A A A A A A A A A T A A A T T A A T A A A A A A A A A T A A A A A A A A T A T A A A A A A A A A A T A A A A A A A T T A T A A A A A A A T A A A A A A A A A A A A A A A A T A A A A A A A A T A T A A A A A A A A A A A A A T T A A T A A T A A A A A A A A A T T A A A A A A T A T A A A A T A A A A A A A T A A A T A A A T A A A A A A A A A A A A A A T A A A A T A A T A A A A A A A A A A A A A A A T A A T A T A T A A A A A A A T A A A A A A A A T A T A T A A A T T A T A T A A T A A A A A A A A A A A A A A +G G G C G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G C G C G G G G G G C G G G G G G G G G C C C G G G C G G G C G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G C G C G G G G C G G G G G G G G G C G G G C G G G G G G C C G G C G G G G C G G G C G G C G C C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C C G C C C C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T A A T T T T T A A T A T A T A A T A T T A A T T T T A T T T T A T T A T A A T T A A T T A A T A T T T A A T A T T T T A A T T T T A A T T A T A T T A A A T T T T T A A A A T A T T T T T T T A T T A T T T A T T A A T A T T T A T T T T T T T T A A T T T T T T T T T A A A A A A T A A A A A T T T A A T T T T T T A A A T A A T T T T A T A T A A T T A T T T A T T T T T T T A A T T T T T T T A T A T T T T A A A T A T A T A A T T T T T A T A T A T T A A A T A T A A A T T T T T T T T A T T A A T T T T A T T T T T T T T T T A T T T T A A T A T T T A T T A T T T +A A T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T A T T T T T T A A T T T T T T T T A T A T T T A T T T T T T A A T A T A T T A A T T T A T T A T T T A T T A A T A T T T T T T T T T T T T T T T T T T A T T T A A T A A T T T T A T T T T T A T A T T T T T T T A A T A T T A T T A T A T T T T T T A A T A T T T T T T T A A T T T T T T T T T T T A T T T T A T T T T T T T T T A T T A T A T T T A A T T A T T T T T A T A T T T T A A T T T A T A A T T T T T T T A T T T T T T T T T T A T A T T T A A T A T T T +C C C G G G G C C C C C G C C C C C C C G C C G G G G C G G C G C G G C G C C G G C C G G C C G C C G G C C G C G C G G C C C C G C C C G C C C C G G C C C G G G G G C C C C G C C G C C G G G C C C C G C G C C G C C G C C C C C G G G G G G G G C C G G G G C G G G C C G C C G C G C C C C C G G C C C G G G G G G C C C G C C G C C G C G C G C C G G C C C G C G C G G G G C C C G C G G G G G C G C G C G G C C C G C G C G G C G C C G G C C C G G G C C C C C C G C G C C C C C G G G C C G G G C C C C G G G G G G G C G G G G C G G G G C C G C G G C C C G C C G G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T A T T A T T A T T A T T A A T A A T T T T T T T T T T A A T T A T A T A T A T A T T T T A T T T A A T T A T T T T T T T A A T A A T A A T T T A T T T A T T T T T T T A A T A A A T T T A A A T T T T T A T T T T T T T T T T A T T T T T T T T A A T T T T T T T T T T A T T A T T T T T T T T A T A T T A T A T T A T T A T A T T T T T T T A A T T T T T T A T T A T T A T A T T T A T A T T T T A A A T T T A A T T A T A T A A T A A A T T A T A A A A T A A T A A A A A A T A T T T T T T T T A T T A A T A T T A T T A T A T T T T T T T T T T T T A T T T T A T A T +A T T T A T T A T A A T A T T T A T T T T T A T T T A T T T A A A T T T T T T T T T A T T A T T T A T T T T T T A A T T A T T T A T T T T T T T T T T T A T T T T A T A T T A A A A T A T T T T T A T A A T T T T A T A A T T T T T A T T T T T A T T T T T T A A T T T A T T T A T T A T T T T A T T A T A A T T T A T T A T T T T T A T A T T T T T A T T A A A T T T T A A T T T A A T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T A T T T A T A A T T A A A T T T T +C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C C G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G G G C C G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G C G G G G G G G G G G C G G G G G G C G C G G G C G G G G G G G G C G G C +C C G C C C C G G C C G C C G G G C G C C C C G G C C C G G C C C G C G C C C C G G C C G G G C C G G G C C G C C G G C C C G G C G G C G G C C C C C C C G G C C C G G G G C C C C C C C C G G C G G C C C G C C C C C G C C C C G C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C G C G G G G C G C C G C C G C G C C G C G G C G G C C C G C C C C C G G G G C G G C G G C C C C C C C C C C G C C G C G C C G C C G C C G C C C G C C G G C C G C C G C G G G G C G C C C C G C G C G C C G G C G C C C C C C C C C C C C C C C C C C G G C C C G C C C G C +A A A T T T T T T A T T A A T T A A T A A A A A A T A A A A T A A T T T T T A T A T A T T T T A A T A T T A A A T T A A A A T T A T A A A T A A A T T A A T A A A T T A A T A T A T A T A T A A T T T A A A T T A A A A T T T T A T T T T T T T T A T T A T A A T A T A T A T A A T A T T A A A A A A T A A A A A T A T A A A T A T T A A A A T A T T A A T T T T T A T T T A T A T T T T T A T A A A A T T T A A T T T A T T T A A T T A T A T A A T A T T A T A A T T A T A T A A T A T A A A A A A A T A T A A T T T T T A A T T T A T A T A A T A A A A A T A A T A A A T A +T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A +C G C C G C G C G G G G C G G G C G G G G G G G G G G G C C G G G G G G G G G C G G G C G C G G G C C G G G C G C G G G G G G G G C G G C G G G G C G G G G G G G G C G C G G G G G G G G C C C C C G G G G C C G G G G C C C C G G G G G G G G G G G G G C G G G G G G G G C G G C G G G G G G G G C G G G C C G G C C G G G G G G C C C G G C G G G G G C C G G C G G G C G G G G C C C G G C G G G G C G G G G C G G G C G C G G G G G C C C G G G G C G C G G G G G G C G G G C C C C G G G C G G G G G C C C C G C C C G G C G C C C G C G G C G G G G C C G G C G C G G G +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G C G C G G G G G G G G G C C G G G G G C G G G G G G G G G G G G G G G C G G G C G G G G C +A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A T +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C C C C C C C C G C C C C C C C G C C C C C C G G C C C C C C C C C C C C G C G G C C C C G C C C C C C C C C C C C G C C C C C C C G C C C C C C G C C C C G C C C C G C C C C C C C C C C C C C G C G G G C C G G C C G G C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C G C C C C G G C G C G C C C G C C C G C C C G C C C C C C C C G C C C C C C C C C G C G C C C C G G G C C C C G G C C C C C C C G C G C C C C C G C C C C G G C C C G C G C C C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A T T T A T T A T A T T A T A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T T A A T A T A A T T A T A T T T T A A T T A T A A A A A A A A A A A T T A T T A T A T T T A A T T A A T A A A A T A T A T T A T A T T T A A A T A A A T T A T T T T A T A A A A T A A T A T A A A T T A T A A A A A A T A A A A A A A A A A A A A A A A A A T T A A A A A T A A A A T A A A A A A A A A A A A A A A A A A T A T A A A A A T A A A A A T A A A A A A T A A A A A A A A A T A T A A T A A A A T T A A A A T A A T T A T A A T A A A A A A T A A A T A A T T A T +C C C G G G C G C C G G G C G C G C C C G C C G G G G C G G G C C C G G C C G C G G C G C C C C C C C C G C C C G C G C G C G G C G C C C G C G G C C C C C G C G G G G G C G G C G C G C G C C G C G G G C G G C G C C C C G G G C G C C C C C C C G C G G C G C C C C G C G C C G G G G G G C C C C G C G C G C C G G C C C C C G G C G C G G C G G C G G G G G C C C G G G C C G G G G G C G C C C C G C C C G G C G C G G C G C C G C C G G C C G G G G C C C C G C C G C G C G G G G C C C G C G C G C G G G G G G G G C C C C C C G G C C C G C G C G C G C C C C G G C C +G C C C C C C C C C C C C C C C G C C C C C G C G C C C G C C C C C G C C G C G C C C C G G C C C C G C C C G C C G C C C G C C G C G C G C C C C G C C C G C C C C C C C C C G G C C G C C G G C C C C C C C C C C C C G G C C C C C C C C C C C C C G C C C C C G C C G C C C C C C C G C C C C C G G C C G G C C C C C C C C C C C C C C C C C C C C C C C G G G C G C C C C C C C G G C G C C C C C C G G C C C G C G C C G C C G C C C G C C C C G C C G G C C C G C C C C C G C G C G C G G C C G C C C G G C C C C C G C G C C G C C G C C C C C C C G C C C G C G C C G +T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T A T T T T A T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A T A T A A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G +G G G C C G G G C G C C C C C C G G G C G C G G G G G C G G C C C G C G G G C G G G C G G G G C G G C C C C C G G G G G G G C C G C G G G C C C C G C G C G G G C C G G C C C G C C G G G G C C G G G C C C G C C C G G G G G G G G G G G G G G G G C G C G G G G G G G G G C C C G C C G C G C G G C G C G C G C C C G G C C C G G C C C C G G C G G G C C G G G G C G G G G G C G C C G C G G C G G G G G G C G G G C C C C G C C G C C G G G C C C G G C C G C C C G C G C C C G G G G G G C C C G C C C G G G G C G G G G C G G G G G G G G C G G G G G C G G G G G C G C G +T T T A A T T T T T T A A T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T A T T T T T T A T T A T T T T A T T T T T T T T T A A A T A A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T A A A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T A T T T +T A A A A A A A T A A A T T A T A A A T A T T A T A A A A T A A T A A A A T T A A A T A A A A T A A A T T T A A T A A A A A A A A T A A A A T A T A T A T T A A T A A A T A A A A A A T A T A A T A A A T A A T A T A A A A T T A A A A A A A A A A T A T A A A A A A A T A A T A A T A A T A T A A T T T A A A T T T A A T T T A A T A A A A A T A A A T T T T T T T A A A A T T A T A A A A T A A A A A A A T A A A A A T T A T T A T T A A A T T A A A T A A T T T A T A T T T A T A T T A A A T A A T T T A A A T A A A T T A A A A A T T A A A A T A A A A A A A A T A T T +G C C C C C C C G C C C G G C G C C C G C G C C G C C C C G C C G C C G C G G C C C G C C C C G C C C G G G C C G C C C C C C C C G C C C C G C G C G C G C C C G C C C G C C C C C C C C G C C C C C C C C C G C C C C C C G G C C C C C C C C C C G C G C C C C C C C C C C G C C G C C G C G C C G C G C C C G G G C C G G G C C G C C C C C G C C C G G G C C C G C C C C G G C G C C C C G C C C C C C C G C C C C C G G C G G C G G C C C G G C C C G C C G G G C G C G G G C G C G G C C C G C C G G G C C C G C C C G G C C C C C G G C C C C G C C C C C C G C G C G G +G G G G G C G C C G C G C C G C C G G C G C C G C G G C C C G C C C C C G G C G G G C G G G G C G G C C C C C G C G G G C G G G G C G G G C C C C C C G C C G G C G C G C C C G G G G C G C C C C G G G C G G C G C C G G G C C G G G G G G G G G G C G C C G G G G G G C G C C C C C C G C G C G G C C C G C C C C C C C C C C G G C G G C C C C G G G C C C C C C C G G G G C C G C C C G G C C C G C G G G C C C G C G C C G C C G C C C G G C C G G G C C G C C C G C G C C C G C G C C G C G C G C C C C G G C C C C G C C G G G G C C C G C C C C C G C G C C C G C G C C +T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +T A A A A A A T A A A A T A A A A A A A T A T T T T A A T T A A A A A T A T A T T A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A T T A A T T A T A T T T A A A A A A T A A A A T A A A A T T T T A A A A A T T A A A A A A A A A A A T T A A A A A A A T A A A A A A A A A T A A A A T A A A T A A T A T A A A A A A A A A A A A A A A A T T T T T A A A A A T A A A A A A A T A A A A T T A A A A A T A T T A A A T A A T A A A A A A A A A A A A A A A A A A A A T A T T A A A A A A A A T A A A A A A A T A A A A T A T T A A A A T T A A A A A T A T A A T +G G G G C G C G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G C G G G G G G G C G G G C G G G G C G G G G G G C C G G G G G G G G G G G G G C G G G G C G G G C G C G C G G C G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G C G G G C G G G G G G G G G G C G G G G G G G G G C G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G C G G +G G G C G G G C G C C C C C C C C G C G C G C C C C G G G C G G G G G C C G G C G G C C G C C G C G G G C C G G G G G C C G C C G G G C C G C G G G C C C C C C C G G C C G G C G G C G C C G G C G C G C G C C G C G G C G C C C G G C C C C C C G G C C G G G C G C G C G G C G C C G G C C G C C C C C C G G G C C G C G C G C G C C C G C C G C G C G C C C G C C C C G G C C C C C G C C C C C C G C G G C G C G G C C C G C C G C C C C C G C C C C C G G G C G G C C C C C C C C C C C C G C C G C G C C C C C C C C C C G C C C G C C C C C G C C G G C C C C C G G G C +T A T A A A A A A A A A A A A A A A A A A A A T A T A A A T A A A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A T A A A A T A A A A A T A A A T A A A A A A T T A A A A T A A T T T A A T T A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A T A A A T A A A A A A T A A A A A A T A T A A A A A A A A T A A A A T A A A A A A T A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T T A A A A T A T T A A T A T A A T A A A A A T A A A A A +T A A A A A T A A A A A A A A A A A A A A A A T A T A A T T A A A T A A A A A A A A A A T A A A A T A A A T A A A T A A A A A A T A T A T A A A A T A A A A A T A A A T A A A A A A T T A A A A T T A A T A A A A T A T A T A A A A A A A A A A A A A A A T A A A A A A A T A A A T A A A A A A A T A T A T A A A A A A T A A A A A A T A A A A A A A A A A T T T A A T A A A A A A T A A A A A A A A A A T T A A T T T A A A T A A T A A A A A A A A A A A A T A A A T A A A A A A A A A A A A T A A A A A A A A T A T T A A A T T A T T A A T A T A A T A A A A A T A A T A A +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C C C C C C G G G G G G G C G C G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G C G G G G C G G G G G G G G G G G +C G C C C G G G G C G G C G G G C G C G C C C C C C G G G C G G C G G C C C G C G C G G G G C C C G C C G C C G G G G C C G G G G G G C C G G G C C C C G C C C C G G C C G G C C G C G C C C C C G G G C G C C G C G G C G C C G G G C C C C C C G G C C C G G C G C G C C G G G C C G G C C G C C G C G G C C G C G G C C C G C C G G C C G C G C G C G C C C C C G G C C G G G C C G C G G C G G G G C C G C C C G C C C G C G G C G C C C G G C G C G G C G G G G G G C G G G C C C C C G C C G C C G G C C C C G C C G C C G C C C C C C C G C C C C G G C C C C C C G G C +A A A T T A T A A T A T T A T T A A T A T T T A T A A A T A A A T T A T T A A A T T A A A A T T T T T T T A T A T T A T T T T T T A T T A A A A T A T T A T T A T T T A T A A A A A A T T A T T A T A T A T T T T A A T T T T T T A T T T T T T T A A A T A A T T T T A T A A A A T T A A T T A A A T A T A T A T T A A T T T A T A A A T T A T A T A T A T A A A T T A T T T T T T A T A T A T A T T T T T T T A A T T T T A T T A T A T T T A T T T T A A T T T T A T T T A T T T T T T T T T A A T A A T T T T A A A A A T T T T A A A T T A A A T T T T A T T T A T T T T T +A A A A A A A A A A A A A A A A A A A A A A A T A T A A A A A A A A A A A T A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A T A A A A A T A A A A A A A T T A T A A T A A T A A A T A A A A T A A A A A A A A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A A A T A T A T A T A A A A A A A A A A A T A A A A A A A A A A A T T A A A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A +C G G G G C C C G G G C G G G G G G C G G C G G C G G C C C G C G C C C C G G C C C G G C G G C G C G G C G G G C C G C G G G G C G C C G C G C C G C G G G G G C G C C C G C G G C G G G G G G G C G C G G G C G G G C C C G G C G C C C C C C C G C G C C G C C G C G C G C G C C C C G G C G C G C G C G C G C C G C C C G G C G G G G G C C G C G G G C G G G C C C G G G C C G G G G C G C C C C C G G C C C C C G C C G G C G G G C C C G C C G C G G G C C C G C C G G C C C G C G C C G G G C C G C G C C C G C C G C C C G C G C G G G C C C G C C G C C C G C G C C C +C G C G G C G C C G C C C C C C G G C G C C C C C C C C C C C C G C C C C C C C C C G C C C G C G C C G C C C G C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C G G C G C C C C C C C G C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C G C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C G C C C C C C G C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C +T A T T T T T T T T T T T T T T T A T A A T A A T A T T A T T T T A T T A A T T T A T T T T T T T T T T T T T A T A T A T T T T A T A T A T T T T A A A T A A A T T T T A T T A T T T T A A T T A T T T A T A A T A A A T A T T T A A A A A A A A A T A T T A T A T A A A A T T T T T T T T T T T A T A T T T T T A T T T T T T T T T T T T T A T A T T T T T A A A T A A A A T A A T A T T A T T T T T A T A A T T A T T A T T T A T T A A T A T A T T A T T A T T T A T A T T T T T T T T T T T A T T T T T T T T T T T T T A A T T A T T T A T T T T T T T T T T T T T A T T +T T T T T A T T T T T T T T T T A T T T T T T T T T T A T A T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T A T A A T A T T T T T T T T T T T T T T T T T T T T A T A T A T T T T A T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T A A T T T T T A A A T A T T A A T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T A T A T T A T A T T A T T T A A A T A A T T T T T T T A T T T T A T T T A T T T T T A T T T T +G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G C G G G G G G G C C G G G G C G G C G G G C G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C C C G G G G C G G G G G G G G G G G G G G G C G G G G G C G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G C G G G G +C C C G C C G G C C C C C C C C G C C C C C C C C C C C G C C C C G C C C C C C C C C C G C C C C G C C C C C C C G C C C C C C G C G C C C C C C C C C C C C C C C C C G C C G C C C C C C G G G G C C C C C G C C C G C G C C G C G C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C G G C G C G C C C C C C C C C C C G G C C C C C C C C C C G G C C G C C C C C C C C G C C C C C C C C G G C C C G G C G C G C C G C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C G C C C C C C C C C C C C C G C C +A T A T A A T T T A A A A T A T T T T T T A T T T T T A T A T T A T A A A A A A A T A A T T A T A T T A A A T T T T A T A A A A T T T T T T T T A A T T T T T T A A A A T T A T T A T A T T T T T T A A T A T T A T T T A T A A T T T A A A A A A T A A A A T A A A A T T T A T A A A A A A A T A T A T A A T T A A T A A A A T A T A A A A A T A A A A A A A T T T A T T T T A A T T T T A T A A A A A T A T A A A T A A T A T A T A T A T A T A A A A T T T T A A A T A T T A A A A A A A A A A T A A T A A A A A T A A T A A T A A T A A A T A A A A A A A A A A A T A T A A +A T T A T T A T T T T T T A T T T T T T A T A A A A T T A A T A T A T T A A T T T T T T T T T T T A T T T T T T T A T T T T T T T T A T A T T A T T A T T A A A T T T A A T T A A A A T A A T T A A T T A T A A T A T A T A T T T T A A A A A A A T T A T A T T A T A T T A T A T T T T T T T A T A T A T T T A T T T T T T T A T T T T T T T A T T T T T T T A A T T T T A A T T T A A A T T T T T T T A T A T A A A T T A T T T A T A T T T T T T T T T A T A T T T A T A A T T T T T T T T T T T T A A T T T T A A A A A T T A T T A A T T A T A T T T T A T T T T T T A T T +G C C C G G G G C G C G G C G C G G G C C G C C C C C G G C C C G G G G C C C G G G G C G C G C G G C G C C C C G G G G G C G G C C G C C C C C G G C C C C C C G G G C G C C C C G C C C C G G C G C C C C C G C C C G G G G G C C G C C C C C C C G C G C C G C C C C G G G C G G G C C G G C C C G G G G C C G G C G G G G C G C C G C C C C G G G G C G G G G G G G C C C G G C C C C G G G C G G G G C G G C C G G G G G G G C C G G G G G G G G G G C C G G G G G G C C G G G G G G G G G G C G C C G G G G C C C C C G G G G C C C G G C C C C G G G C C C C G C G G G G +C C C C C C C C C C C C C C C C C C C C C C C G C G C C C 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T A T T A A A T A A A T A A A A T A A A A A A A A A A A A A A +T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A A A A A A T T T T T T T A A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +C G G C G C C C C G C G C C C C C G G C C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C G G C C C G C G C C C C C C C C C C C C C C C C C C C C C C C G C G C G C C G C C C C C C C C C C C C C G C C C C G C C C G C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C G C C C G C C C C C G C C C C C C C C C C C C G C G C C C C C C C C G C C C C G C G C G C C C C C G C C C C C C C G C C G C C C C C C C G C C C C C C C G G C C G G C G G C C C C G C C C C C C C G C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C G C G G +T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T A T A T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A A T T T T T T T A T T T T A T T T T T T T T A T T T T T +A T T T T T T T T T A T T A A A T T T A A T A T T A A T T T A A T A T T T T T T T A T A T T T T T T T A T T A A T T T T T A A A T T T T T A A A T T T A A A A T T T T T A A T T A T T T A T A A T T T T T T T T T T A A T T T T A A T T T T T T T A T T T T A T T T T A A T T A T A T T A T T A T T T T T A A T T A A T T T T A T A A T T A A T A T T T A T T T T A T T A T T T T A T T T T T T T T T T T T T A T T T T T A A T T A T T T A T T T A T T T T A T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T A T T T T T T T T T T T A T A T T T A A T A T T T T +C G C G G C G C C G C C C C C C C G G C C C C G G C C G G C C C C C C C C C C G C C G C G G G C C G G G C C C C G C G G G C C C C C 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T T T T T A A T A A A A T A T A T A A T T T T T T A A A T T T A A A A A T T T A A T A T A A T A T T A A T A A T T A A A A A A A T T T T T T A A A A A A A A T T A T T T T T A T A A A T A T A T T T A A T T A A T T A A T A T T A A A A T T A A T A A A T A A A T A T T T T T T T A T T T T T T T A T A A A T T T A T A T T A T A T T A T A T T T T T T T A T T A A A A T A T T A T T T A A A T T A T T A T T T A A T T T A A T T T A T T T T T T T T T T T T +T T A A T T T A A A T A T T T A T A A A A T A A A A A T A T T A T A A T T A A A T A T T T T A A T A T A T T A T T T A A A A T T A A T T T T T T T A T T A A A A A A T T T A T A A T T A T A T T T T T T T T T T T T T T T A T T T A T T T T A T T T A A A T T T T T T T T T A A A T A A A A A T A A T T A T A T T A T T A A A T T A T T T T T A A T T A T T T T T T A T A A T T A A T A T T A T A A T A A T A A T T T A T T T A A A T A T A A T A A A A A A T A A A A A A T A A A T T T T T T A A T A T A A T T T T A T T A A T A T T A T A T T T A A T T A A A A A T T A T T T +C C G C C C C G C G C G C C C G C G G G G C G G G G G G G C C G C C G C C G C G C G G C C C G G C G G G C C G C C C G G C G C C G G C C C G C G C G C C G G G G G G C C C G C G G C C G C G G G C G G C G C C C C G C C C G C C G G C C C C G C C G G G G C G C C C C C G C G G G G G G G G G C G C G C G C C C G G C C G G G C C G G C C G G G G C C G C G G C C C G C C G C C C G C C C C G G C C C C C C C G G C G G C G G C C G G C C G G C G C G G C G C C C C G C C C C C C C C C C G C C C C C G C C C C G C C C C C G G C C C C C G C C C G G G G G C G G C C G G G G G +G C C C G C G C C C C C C C C C C C C C C G G C G C C G G G C C C G C C C C C C G C C C G G C C G C C C G C C G G G C C C C C C C C G G C G C G G C G G G C C G C C G G G C C C C C C C C G G G G C G G G G G G G G C G C C G G G C C C C C C G C G C C C C G G C C C G G G C C C G C C C C C C G C G G G C C G G C G G C C C C G C C C C C G G C C C C C C G C G C C G C C C G C C C C C G C G G C C G C G C C G C G C G G G C C C G C G C C C C C C C C C G C C C C C C G C C C C G C G G G G C G G G C C G C G C C C C C C G C G G C C C G G C G C C G C C C C G C G C G G G +A A A A T A A A A T A A A A A A A T T A A A A T A A A A A A A A A A A A A T A A A T T A A A A A A A A A A A A A A A T T A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A T A A A A A A A T A A A T A A A A A A A A A T A T T A A A A A A A A A A T A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T T A A A A A A A T A A A T A A A A A A A T A A T A A A A +A A A T T T T A T A T A T A T A T A A A A A A T A A A A A T T A T A A T T A T A T A A T T A T A T A T A A A A A A A A A A A T T A A T T T A A A A A A A A T A A A A T T A A T A A A T T T A A A T A A T A T A T T A T A T A T T A A T T T T A T T A A A A A A T T T T T A T A A A A A A A A A A A A A T A T T T A A T A T A A T T A A T T A A A A T T A A A T T T A T T A A A T T A T T T A A A A A T A T T T A A A A A A A A T T A A T A A A T A T A A T A T T A T A T T T T T T T T T T A T A A T A A T A T T A A T A A T A A T T T T A A T T A A A A A A T A T A T A A A A A +G G G C G C G G C G C G G G C G C G G G G G G G G G G G G C G G C G G C C G C G G G G C G G G G G G G G G G G G G G G G G G C C G G G G C G G G G G G G G G G G G G C G G G C G G G C G C G G G G G G G G G G G G G C G C G G G G G C C C C G G C G G G G G G G C C C G G G G G G C G G G G G G G G G G G C C G G G G G G G G G G G G C C G G G G C C G G G G C G G G G G G G G G G C C C G G G G G C G C G C G C G C G G G C G C G C G G G G C G G G G G G G C G C G C C G G C C C G C G G G G G G G C G G G C G G G G G G G G C G G C G G G G G G G G C G C G G G C G G G G G +C C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C G C G G C C C G C G G C C C C C C C G C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C G C C G C C C C C G C C C C C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C G C C C G G G G C G C C G C C C C G G C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C +A A T T A A A A T T A A T A A T A T T T T A A A A T A A A A T A A T T A A T T T A T T A A A A T A T A T A T T A A A T T A A A A T A A A A A A A T T A A A A T A T T A A A A A T A A A A A A A A A A A A A A T T A A A A A T A A A T A A A A A A A A T T T A A A A A A A A T T T T T T A A T T A T A A T T A T A A T A T A T A A A T T A A T A A T A A A T T A A A A A A T A A A A T A A A A T A A A A A T T T T T A T A T T T T T T T T A T T A T T T T T T A T A T T T T T T T T A A A A A A A A A A T T A A A A A T A A T T A T A A T A A A A A A T A T T T T A A A A A A A A +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T A T A T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G G G G G G G C G G G C G G G G G G G G G G C G C G C C C G G C G C G G G G G G G G G G G G G G G G G G C G G C G G G G G C G G G G G G G G G G G G G G C G G C G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G C G G G G G G G G G G G G C C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G C G G G G G C G G C C G G +C G C G G G G C G C G C C G G C C C C C C G G G G C C G G C C C G G C G G C G C G C C G G G G C G C G C G C C G G G C C G C G G C G G G G G G G C C G G G G C G G C C G G C G C G G G G G G G G G G C G C G C G G C G G G C G G G C G G G G G G G G C C C G G G G G G G G C C C C G C C C C C G G G G C C G G G G C G C G C G G G C C C G C G G C G G G C C G G G G G G C C G G G C G G G G C G G G G G G G G C C G C G C C C C G C C C G C C G C C G C C C G G G G C G G G C G G G G G G G G G G G G C C G G G G G C G G C C G G G G G G C G G G G C C G C G C C G G G C G G G +A A T A T A A T A T A T A A A T A T T T A A A T A T T A T A A A A T T A A T A T A T T A A A A T A T A A A A A A A A T T A T A A T T A A A T A T A T A A A T A A A A A A A T A T A A A A A T T T A A A A A A A A A A A A T T A A A A A A A A A A A A T T T T A A A A A A A T A T T A T A T T A A T A A T T A A A T T T A A A A A A T T A A T A A T A A A A T A A A T A A A A A A A A A T A T T T A A A A A A A T A T A A A T A T A T A T A T T T T T A T T T A A A A T A A A T A A T A T A T A A A A A A T A A T T T T T T T T T A A T A T T A T T T T A T T A T T T A T T A T T +A A A A A A A A T A T A A A T A A A A A A A A A A A A A A T A A T A A T A A T A T A A T A A A A A A A T T A T A A A A A A A T T A A A T A A A A T A A A A A A A A A T A A A T A A A A A A A A A A A A A T T A A T A T A A A T T A A A A A A A T A A A A A A A T A A A T A A A A A A A A A A A A A A A A A T T T A A A A A T A A T A A T A A A A A T T A A A A A A A A A T A A T A T T A T A A A A A T A A A T A T A A A A A A A A A A A A A A A A A A A A A T T A A A T A A A A A A T A T A T A A T A T A A T A A A A A A A A A T T A T A A T A A A A A A A T A A A T A A A A A +G G G G G G C G G G C G G G C G G G G G G G G G G G G G G C G G G G G G C G G G G G G C G G G G C G G G G G G G G G G G G G C C G G C G C G G G C G G G G G G G G G C C G G G G G G G G G G G G C G G C G G G C G G G G G G C C G G C C C C G G C G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G C C G C C G C G C G C G G G G G G G C G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G +G G C C C G C C C C C C G G C C C G G C C G C C C C C C C C G C C C G C C C C C G C G C G G G C C C G G G G G G G G G C G C C C C C C G C G G G C G G G C C C C G C C C G C C C G C C G C C G G C C C C G G G C G C C G C C C C C C C C C C G C C C G C C C C C C C C G G G G C C G C C C C C G C G G G G C G G G C G G G G G G G C G G C G G G C C C G G G G G G C G G C C G G G C C G C C C G G G G G C C G C G C C G G G G G C C G G G C C C C G G C G C G G G C C G C C G C C C C C C G C G G C G G G G C C G C G C C G C G G C C C C C C C C C C C C C C C C C C C C C G G +T T A T A T A A T A A A T T A A T T T A A T A A A A A A A A T A T A T T A A T A T A T A T T T A A A T T T T T T T T T A T A A A A A A T A T T T A T T T A A A A T A A A T A T A T A T T T A T T A T A A T T T A T A T T T A A A A A A A A A T T A A T A A A A T A T A T T T T A T T A A A A A T A T T T T T T T T A T T T T T T T A T T T T T T A A A T T T T T T A T T T A T T T T T T T A A T T T T T A A T A T A A T T T T T A A T T T A A T A T T A T A T T T A A T A A T A A T A T A T A T T T T T T T A T T A T A A T A T T A A T A A A A A A A A T A T A A A T A A A T T +A T A T A A T A T A A T A A A A T T T T A A A T A A A A A A A A A A A A T A T A T A A A A A A A A A A T T A T A A A T A A A A A A A A T T A A A A T A A A T A A A A A A A T T A A A T A T A A A A T A A A A A T A A A A A A A A A A T T T T A A T A A A A A A A T T T T T A A A A A T A A A A A A A T A A T A T A A A A A T A A T A A T T A A A A A A A A A A T T A A A T A T T A T A A A A A A A A T A T T A A T A A A A A A A T A A A A A A A A A A A A A T A A T A A T T A T T A A A A A A A A T A T A A A A A A A A A A A A A A A T A A A A A A A A A A T A A T T A A A A A +G C C C G G C C C C G C G C G C C C C C G C G C G C C C C G C C G C C G C C C C C C C C G C C C C C C C C G C C C C C C C C G G C C C C C G G G C C C C G C G G C G G C C C C G G C G G C G C C C C C C C C C C C C G G C C G G G C C C C C G G C C C C C G C G C C C C C C G C G G C G C C G G C G C C C C C C C C G G G C C G C C C G C C C C C C C G G C C C C G G G C C C C G C G G G C C G C C C C C C C C C G G G C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C G C G G G C C C C C C C G C G G C G G C C G C G G C G C G C G C C G G C C C C C C G C C C G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T A A T T T T A A T T A T T T T A T T T T T A A A A T A T T T A A A A T A A A T A T T T T T A T A A T T A T A T T T A T A T T A A T T T A A A T T T T T A T A T T T T T T T A A A T T T A A A T T T T T T T T T T A T T A T T T A T T T T T A T A A A A A A A T T T T A A T A A T T T A A T A A T A A A A T T A A T T T T A A T A T T T T T T A T T T A T T A A A T T T T T T T T A T A A A A T T T T T T T A T A A T T A T A T A T A A A A T A T T A T A T T T T A T T T T T T T T T T A T T T A T T T T T T A A T A A T A A T T T A A A T A A A A T A A T A A T A A A A A A +T T T A T T T T A T T T T T T T T A T T T T T A A T A T A T T T A T A A T A A A T T T T T T T A T A A T T A T A T T T A T T T T T T T T T A T A T T T T T A T A T T T T T T T A T T A T A A A A T T A T T T T T T A A T T T T T T T T T T T T A T T A A A A T A T T T T A A T T A T T T T A T T T T A A A A A A A T T T T A A T T A T T T T T T A T T T A T T A A A T T T T T T T T T T A T A A T T A T T T A T T A A T T A T A T T T A A T A T T T T A T A A A T T A A T T T T T T T T T A T T T A T T T T T T A A T A A T T A A T T A A T T T A A T T A T T A T T T A T T A A +G G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G C G G G C G G G C G G G G C G C C G G G G C G G G G G G G G G G G G G C G C G G C G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G G G G C C G C G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G C G G C G G G G G G G C G G G C G G G G G C G C G G G G G C G G G G G C G G G G G G G G C G G C G G G G G G G G G G G C G G G G G G C G +C C G C G G G C G G G G C C G C C C C G C C C G G C G C G G C C G C G G G G G G G G C G C C C G C C G C G G C G C C C G C G G G C C G G G G C G C G C C C G C G C C G C C G C G C C C C C G G G C G C C C C C G C C G C C C C C C C G G G G C G G C G G G C C G G G G G C C C G G C G C C G C C C C C C C C G C G G G C C C C C G C C G G C G C C G G C G C G C C C C C C C C G C C G G G G G G C C C C G G G G G C C C C C C C G C C C G G C C G C C G C C C G C G G G G G C G G C C C C G C C G C C G C C C C G C C C C C G G G C C G C C C C C G C C G G C G G G G G C G G G +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T A T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A T A T A T A A T A T T A A T T A A T A A A T T A T T T A A T T A A T A T A T A T A A A A A A A A A A A T A A T A T T A T A A T T A A A T T T A T A A A T A T A A A A T T A T T T A A A T A A A T A A A A A A A A T A A T A A A A A A A A A T A A A T T A A T A T A A A A A T T A T A T T A T T A A A A A T A A T A A A A A T A A A A T A T T A A A A T A A A A A A A A T A A A A A A T T T T A A A A A A A T A A A A A A A A A T A A A T A A T A A A A A A A A A T A A A A A A A A A A T A A T A A A A A A A T A A A A A T T A A A A A T A T A T T A T T A T T T A A T T A T +G C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C C C G C G C C G C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C G C G C C C C G C C C C C G C C C C G C G G C C G G G G C C G C C C C G C C G G G G C C C C C C C C C C C C C C C C C G C G C C G C C G C C C G C C G C C C G C G C C C C C C C C G C C C C C C G C C C C C C C G C G G G C C G C C C C C C G C C C C C G G C C C C C G G G C G C G G G C G G G C G G C G C C C C C C C G G C G C G G C C C G G G C G C G C G C 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G C C C C C C C C G C C G C C G G C C G C C G C C G C G G C G C C C G G C C G G G C C C C G G G G C C G C C C G C C G G G C C G C C C G C G C C G C C G C C C C C C G C C C C C C C G C C G C G G C C G C C C C G C C C C C G G C C C C C C C C C C C C C G C G G G G C C G C G +G C G G C C G C C G C G G C C G G C G G G C C G G G C C G C C G C C G G C G C G G G C C G G G C G C C G C G G C C G G G C G C C G G C C C G G G G C G G C G C G G C C C G G C G G G G G G G G G G C C C G G G C G C C C C C C C C G C C C C C G C G G G G C C G C C C C C G C G C C G C G G C G G C C C C C C C G G C C G C G G G C C C C C G G C G C C G C G C C C G G C G G G G G C C G G G G G G C G C C G G C C G G G G G G C G G G G G C C G G G G G C C G G C G C C C G C C C G C C G C G G C C G G G C C G C G C C G G G C C C C C G C G C C G G C G C G G G G C G G G G +T T A T T A T A T T A T T T A T T A T T A T T T T T T T T A T T T T T T A T A T T T T T A A T A T A A T A T T A A T T T T T A A T T A A A T T T T A T A T T T T T T A T T T T A T T T T T T T T T A A A T T T A T A T A T A T T T T A A A A T T A T T T T A T T A T A A A T T T T T T T T T T T T T A T T A A A T T T T T T T T T T T A T T T T A T A T T T T A A A T A T T A T T T A T T T T T T T A T A A T T A A A T T T T A A T T A T T A T T T T T T A A T T A T A A A T A A T T T T T T T T T A T T T T T T A T A A T T T A T T A A T T T A T T T T T A T T T T A T T T T +A A A T A A A A A A A A A A A A A A T A A T T A A A A A A A T A A A T A A A A A A A T A A A A A T A A A A A A A A T A A T T A A A A A A A A A A A A A A T A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A T A A A T A A A T A A A A A A T T A A T A T T A T A A T A A A A A A A A A A A A A A A A A T A A A A A A A T A A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A T A A A A A A T A A A A A T A A A A A A A A A A A A A A A T A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C G G C C C C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C G C C G G C C C C C C C C C C G C C C C C C C C C C C C C C C G G C G G G C G G C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C +C C C C G C C C G C C C C C C C G C C G G C C C C G G C G C G G G G C G C C G C C C C G G C C C C C C G C C C C C C C G C C C C C C C C C G C C C C C G C C G C C C C C C C G C C C C G C G G G C C G C C C C G C G G C C G G G C C C C C C C C C C C C G C C C C G C C C C C C G C C C C C C C C C C C C C G C G C G G G G C C G G G C C G C G C G C C C G G C C C G C G C C G C G G G G G C C C G C C G G G C C C C G C C G C G C G C C C C G C G C C G C C G G G C G G G G G G G C G G C G C C G C C G G G G C C G C C G C C G G G G C C G C C C C C G C G C C C G C C C G C +A T T T A A T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T A T A T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T A T T T T A T A T T T T T T T T T T T T A T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T A T T A T T T T T T T T T +A A T A A A T T A A A T T T A T A T A T T A A T T T T T T A A T A A A T T T A T A A A T A T A T A T A T A T A A T A T T A A A A T T A A A A T A T T T T A T T T A A A T T T A T T T T T T T T T T T T A T A T T T A A A A A A A A T T T T T A T T T T T A T A T T T T T T A A T T A T A A T A T T A T T A T T T T T A A T A A T T A T A T T T T T A T A T T T T T T A T A T T A T A A A A T T A A T T A T T A T T T T A T A A T T T A T A T T A T A A A A T T A T T T T T T A T T A A A A A A A T T T A A T A A A T A T T A T A T A A A T T A T T T T A T T A T T A A T T T A T +C C C G C C C G C C G C C C G C C C C C C C C C C C C C C G C C C C C C G C C C C G G C G C G G C G G G G C G G G C C C C C G G C C C G G C C C C C C C C C C C C C G G C C C C C C C C C C C C C G G G C G C G C G C G C C C C C C G G G G C C G C C C C G C C G C G G G C G C C G C C C C C C G C G G C G G G C C C C C C G C C C C C C C C C C C G C C C C G G C C C G C C C C G C C C C C C C C G C G G C C G G C C C C C C G C C C C C G C C C C C C G G C C G G C G G C G G C C C C C C C C C G C C C C C C G C G G C C C G C C C G C C C G C C C C C C C C C C C C C C C +C C C G C G G G C C G G C C G C C C C C G C C G G C G C G G C C C C C C G G G C C G G C G C C G C G C G G C G C G C C G C G G G C C C G G C C C C C G G C G G C C C G G C G C C C C C C C G C C C G G G C G C G C G C G C C C C C C G G G G C G G C C G G G C G G C G G G C C G C C G C C G C C C C G C C G G G C G C C C C C C G C G G G G C C G C C C G C C G G C C C G C C C C G C C C G G C C C G C G G C G C G C C C C C C G C C C G G G C G C C C C G G C C G G C G G C G G C C C C G C C C G C C C C C C G G C G G C G G G C C G G G C G G G C G G C G G G C G G G G C G +T A T T T A A A T A T A A A T A A T A A A T A A A A A A A T A A A A A A T A A A T T A T T T T T T T T T A A T A A A A A A A T T A A A T A A A A A T A A A A A A T T T T T A T T A A T T T A A A T T T A T T A T T A A T A T A A A A T T T T A A T A A A A A A A T A T T T A T A A T A A A A A A T A A A A A T A A A A T T A T A A A A A A T A A A T T T A A A A A T T T T A T T T T T T A A A A A A A A T T A A A A T A A T A T T A A T T A A T A A T A A A A A A T T A T T A T T T A T A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A +A A A T T A A A T A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A A T T A A T A T A A A A 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G +G G G C C G G G C G G G G G G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G C G C G G G G G G G G G G G G C C G G G G G G G G G G G G C G G G G C G G G G G G G G G G C C C G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C C G G G G G G C G G C G G G G C C C G G G G G G G G C C G G G G G G G G G G C G G G G G G C G G G G G G G G G C G G C C G C C C G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G C G C C C C C C G C C C G C C C G C C C C C C C C C C C C C C C C C C G C C C G C C C C G C G C C G C G C G C C C C C G C C C C C G G C C C C C G C C C C C C C C C G C C C G C C C G G C C C C C C C C C C C C C C C G C C C C C G G G G C C G C C C C C C C G C G G C C C C C C C C C C C C C G C G G C G C C C C C C C C C C C C G C C G C C C C C C C C C C C C C C C G G C C G C C C C C C C C C C C G C C C G G C C G G C C G G C C C C C G C G G C C G C C G C C C G C C C C C C C C C C C C C G C C C C C G C C G C C G C C C C C C C C C C C C C C C C G C C C C C C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G G C G C C C C C C G G C C G C C C C G C C G C C C C C C C C C C C C C C C C C G C C C C C C C C C G C C C C C C G C C C C C G C C C C C C C C C G C C C G G C C G G G G C C G C C C C C C C G C G G C C G C C G C C C C C C G G C C C C C C C C G C G G C C C C C C C C C G C G G G C C C C C G G G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C G C G C C C C C C C G C C C C C C C C C G C G C C C G C C C C C C C C C C C C C C C C C +A A A A A A T T A T A T T A A T A A A T T A A T T A T T T A A T T T T A T T A T A A T T T T A T A A T A T T A T T T A T A T A A A A T T T T T T T T T T A T T T A A A T A T A T T T T A A T A A T A A A A A T A A A T A A A T T A T T T T T T T T T A T T A T T T T T T A T T T T T T A T T A T T T A A A A A T A T T A T T A T T T T T T T A T T T T T T T T A A T T T A T A A A T A A A T T T A A A A A A T T T A A T T T T T A T T T A T A A T T T A T A A T A A T T A A T A A A A A T T T A T T T A T A T A T A T A A T T T T T T A A T T T A T T T T T A T T T T T T T A T +A T A T T A T T T A A T T A A T T T T T T T T T T T T T T A A T T T T A A T A T T A T T A T A A T T T A T T A T T T T T T T A A A A A T A T T T T A T T T T T T A T A A T T T T T T T T T T T T T T T A T A T T T A T A T A T T A T A A A A T T A T A T A A T T A T A A A T T T T T T A T T A T T A T T T A A T T T T T A T A T T T T T T T T A T T T T T T T T T T A A T T T T T A A T T T T A A T A A T T T T T A T T T A T T T T T T T T A T T T T A T A A T T T T T T T T T T T A T T A T A T T T A T T T T A A T A A T T A T T T A A T T T A T T T T T A A A A A T A T A T +G C C G C C C G C G C C C C C C C G G C G C C C C G C C C C G C G G C C G C C C C C C G G C G G G G G C C C C G C C G C G C C C C C G C C C C C C G C G C C C C G C C G G C C C C C C C C C C C C G G G G C C G G G G C C C G G C C G G G G C C G C C C C G C C G C G G G C G C C G C C C C C C G G C G G C G C G C G C G G G C C C C C C C C C C C C G C C C C C C G G G C C C G G G C G C C C C G G C G G C C C G C C C G C C G C C C C C G C C C G C C G G C G G C C G G C G G C C C G C G C C C C C C G G C C G C G G C C C G C G C G C G C G C C C C C C C C G C C C C C G +G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C G C G C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C G C C C C C C C C C C C C C G G C G C C G G C C C C C C C C C G G G G C C G C C C C G C C G C G G C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C G C G C C C C C C C G C G G C C C G C C C C C C G C C C C C G C C C C C C G G C C G C C G G C G G C C C C C C C C C C C C C C C C G C G G C C C C C C C G C C C G C C C C C C C C C C C C C C C +T T A T T A T T T T A T T T A A A T T T T T T T T T T T T A T T T T T A T T A T T A T T T A T T T T T A A T A T T T T T T T A A A A T T T T T T T T T T T T T T T T A T T T T T T T T A A T A A A T T T T A T T T T T A T A T T A T T T T T T T T T A T T T T T T T T T T A T T T T T A T T A T T T A T T A T A T T T T T T T T T T T A T A T A T T T T T T T A A T T T T T A T T T T T T T T A T T T T T T T T T T A T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T A T T T A T T T T T T T T T T A T T T T T T T A T +T T A T T A A T T T A A A T A A A A A A T T A A A T A A A A T A T T A A T A A A A A A T T A T T T T T A A A A T A A A A T A A A A A T T A A A A A T A T A A A A T T A T T A T T A A A A A A A A A T T T T A A T T T T A T A T T A A T T T T A A T A A A A T A A T A T T T A T A A T A A A A A A T T A T T A T A T A T T T T T A A A A A A A T A A A A T A A A A A A T T T A A A T T T T T A A A T T T T T T T A A T A T A T T T T A T T A A T T A T T A T T T T T T A A T T T T T T T T T A T T A A A T T T T T A T T T T T A A T A T A T A T A T A A A A A A A A T A A A A A T +G G G G C C C C C G C C C G C G G C C C G C C C C C G C C C G C G G C C G C G C C C C C G G G G C G G G C C G C C G C C G C C C C C G G C C C C C G C G C C C C C C C G C C C G C C C C C C C C C G G G C C C G C G G C G C G G C C G G G G C C G C C C C G C C G C G G G C C C C C C C C C C C C G C C C C G G C C G C G G G C C C C G C G G C C C C C C C C C C C G G G C C G G G G C C C C C G C G G G G C C C G C G C G C G G C C G C C G C C C C C C G G C C G C C G G C G G C G C G C G G C C C G C C G C C G C G G C C C G C G G G C G C G C C C C C G C C G C C C C C C +C C C C C C C C C C G C C C G C C G G C C C C C C C C C C G C C C C G C C C C C C G C C C C C C C C C C C C C C C C G C C C G G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C G G C C G C C G C G C C C C C C C C C C C C C C C C C C C C C C C 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T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T A A T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G C G C C C G G C C G G G G G G G G G G C C G G G G C G G G C C C C G C G G G G G G G G G G G G G G G G C G G C G G G G C G G G C C G G G G G G G G G C G G G G G C G G G G C G G G G C C G C C C G G G G G G G G G C G C G C C C G G G G G G G G G C G G G G G G G G G G C G G G G G C G G C G G G C G G C G G G G C C C C G G G G G G G G G C G G G G G G G C G C C G G G C G G C G C G G G C C G G C G G G G G G C G G G G G G G G G C G G C G G G C G G G G G G G G G G G G G C C C C C C C G G G C G G C C C G G G G G G C C G C G G G C G G G G G G G G G G C G G G G C G +C C C C C C G G C C C 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C C G G G G C G C G C G G G C C G G C G G C C C G C G G G G G G C C G G G C G G G C G G G G G G G C G G G G C G C G G G G G G G C G C C C C G G G C G C C G C G G G G G G C C G C G G G C G G G G G G G G G G G G G G G C C +C C C C C C G G C G C G G C C G G C C G C C G G G C C G G C C C C C G C C G C C C C G C G C C C C C C G C C C C G C C G C G C C C C C C C G C G C G G C G G C G C C C G C G C C G G C C C G C C G C C C C C C C C C C C C C C C C C C C C C C G C C C G C C C G C C C C C C C G G C G C G C C G C C C C C C C G C G C C C C C G G C G C G C C C G C G C G C G C G C C C G G C C G C C C C G G C C C C C C C C G G C C C C C C C C C C C G G C C G C G C C C C C C C C G C C C C C C C C C C C C G C G C C C C C C C C C C C G C C G C C C G C G C G G G G G C C G G G C G G C C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +T A A T A A A A A A A A A A A A A T T A T A A A A T A A A A A A A T A T T A A T A A A T T A T T T T T A T A T T A A T A A A A A T T A A A A A A A T A T A A A A T A A A A A A A A A T T T A T T T A A T T A A A T T A A T A A A T A T T T T T A T A T A A A A A T A T T T A T T A T A T A A T A T T A A A A A T T A T A A A T A A A A T A A A A A A A T A A A A A A A A T A T A T A A A T A A T T T A T A A T A A A A A A T T A A A T A A A A A A T A T T A A T T A A A A A T A A A T A A T A T A A A T T T A A T A T A A T A T A A T A A A A A A A A A T A A T A A A A T A T T +G G C G C C G G C G G G G G G C C G G G G C G G G G G G G G G G G G C G G G C G G G G G G G G G 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T A T T T T T T A T T A T T T T T T A T A A A T A A A T A T T T T T A T T T T T A T T T T T T T T T A T T T T T T T T A T T A T A A A T T T A T T +C G G C G G G G G G G G G C G C C C C G C G G G G C C G G G C C G G C C C G C C C G G G C C C C G C C C C C C C G C C G C G G G G G C C C G G G G C C C G G G G C G G C C G G C G G C C C G C C C G G C G G C G C G G G C G C C C C C C C C C G C C C G G C C G C G C C C C G C C C G C G C C G C C G C G G C C C G G G C C C G G C G C G C C G C G C C G C C C G C C C C C C C C C C G C G G C C C C C G G C G C C G C C C C G G C C G C G C C G C G C C C C C C G C G G G C G G C C C C C C C G G C C C C C C C C C C C C G C C G C C C C C C C C G C C G C G G G G C C G C C +G C C G C G C C C G C G C G C G G G G G G C G C C G G G C C G G G C G G G G G G G C G C G G G G G G G G G C G G G G G G G G C C C C G G C G C C C C G G G C G C G C C G G C C G C C G G G C G G C C C G C C C C G C G C G C G G G C G G G G G G G C G G G G C G G C G G G G G G G G G G G G G C G G 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T T T A T A T A A T A T A T T A A T A A T T +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C G C G G C G C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C G G C C C G G G C C C C C C C C C C C C G C C G C C C C C G C C C C C C G C C C C C C C C G C C G C G C C G G C G C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C G C G C G C C C C C C C C G C C G C C C C G C C C G C C C C C C G C C G C C G C C C C C C G C C C C C C C C C C G C C G C C C C G G G G G C C C C C C G C C C G C C C C C C C C C G C C C C C +C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T A T A A T T A T A T T A T A A T A A A A A A A T A A A A A A A A A A A A A T A T A A T A A A A T A A T T T T A A A A A T T T T T A T A A T A A T T A T T A T T T A T T A A T A T T A A T T T T T T T A T A A T T T T T A T A T T T T T T T T A A A A T T A T T T T A T A A A A A T A T A A T +C G C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C G C C C C C C C C C C G C C C C C C C C C C C C C C C C G G C C C C C C G C G C C G C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C G C G C C C C C C G C G G C C C C C C C C G C G C C C C C C C C G C C C C G C C C C C C C C C G G C C G C G G C C G C C C G C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C G C C G C G G C G C C C C C G C C C G C C C C C C C C G C G C G C C +G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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C C G C G G G C C G G G C G C G G G G G C C G G G G G G G G G G G G C C G G G G G G G G G C +G G G G G G G C G G C G C G C G G G G G G G C C C C G G C C G G C G C G C G G G G C C C G G C G C G G C G G G G G G C C G G C C G G G G G C G G G G C G C C G C G G C C G G G G G G G G G G G G G G G C G G G G G G C G G G G C G C C G G G G G G G C G C G G G G C G G G C G G G G C G C G G G G G G G G G G G G G G G G G G C C G C G G G G G G C G C G G G G G G C G G G C G G G G G G G G G G C G G G G G G C G G G C G G G G G G G G G G G G G C G G G G G C G G C G G G G G G G G C G C G C G G C G C G C G G G G G G G G C C G C G G C G G G G C G G G G C G G G G G G G +T T T T A T T T T T T A T A T T A T A T A A T T T T A T T T T A T T T T T T T A T T T T T A T A T T T T T T T T T T T T T A T T T T T A T T T A T T T A T T A T T A T T T A A A A T T T T T A A T T T T T T A T T T T T A A T T A T T T T T T T T A T T T T T T T T T T T T A T A A T T T T A T T T T T T A A A T T T T T A T T T T T T A T T A T T T T T 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G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G C C G G G G G G G C G G G C G G G G G G G C G C G G G G G +A A A A A A A T A A A A A A A A T A A A A A A A T A A A A A A A T A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A A A A A T A A A A A A T A A A A A A T A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T A A A T A T A A A A T T A A T T A A A A A A A T A A A A A A A A A T A A A T A A A A A T A A T A A A A A A A A A T A T A A A A A A A A A A A A A A +T A A T T A A A A A A T T T T A A T T T T T T T A T A A T A A A T A T A T A A T T T T T T A T T T A A T T A A T A A T T T T T A T T A A A T A A A T A T T T A T T T A T A T A A A A A A A A A A A T A A A A T A T A A T A A A T A A T A A A A T A A T A T T T A A A A A T T A A A A T A T A A A A A T T T 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C C C C C C C G G G G G G C G C C G G C G C G C C C G C C C C C G C C C C C G C C C C G C G C C C C G G C G C C C C G C C C C C C C G C C G C C C C C C G G C G C C G C C C G C C G G C C C C C G G C C C G C C C C C C G G G C C C C C G G C C C G C C G G C G C C C C G C C G C C C C G C C G G C C C C C G C C C C +C C C G C C C C C C C C C C G C C G C G G G G C C G C G C G G G C G C C C G G C C G C G G C C C C C C C C C C C C G C G G G G C G G G C C G C C G G G G C C C G C G G C G C C C C G C C G C C C C C C C C C C C C C C C C G G C C C C G G G G G G C C C C G G G G C G G C C C C C C C C C C C C C C C C C C C C G C G C G C C C C G C C C G G G C C C C G C C C C C C G G C G C G C G G C G C C G C C G C G C G G C C C C C C C G G C C G G C C G C C C C C C C G G C C C G C G G C C C C C C G C C C G C G C C C C C C C C C C C C G C C G C C C C G C C C C G G G G C G C C C +T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A T A T A A T A T A T A A T A T T A A A T T A A A A A T A A A T A A A T A A A A A A A A T A A A A A T A T T T T T A A A T T A T A A T A A A A T A T T T T A T A T T A A T A T T T A T T T T T T T A T A T T A T A T A A T T A A T A A A A A T T A A T T A T T T A A A A A A T T T T A T A T T T T T A A A T A T A A T A T T A A A A A A A A T T T A T A A A A A A A T T A A A T T A T T A T T T T A T T T A A A T T T T A A A T T A A T A T T A A A A T A T T A A A T A T A A A A A T A A A A T A T T T A A A A A T T A T A A A A T A A T T A A A T T A T T A A T A T T T A A A +C C C C C C C G G C C G G G C G C C C C G G C G G C C G G G G G G C C G G G C G G C G C C C G G G G G G C C G C G C C C G G C C C C G C C C C G G C G G G G C C G G G G G G C C G C C C C C G G G C G G G G G C C G G C C G G G G G G G G G G G G C G G G G G G C G G G C G G G C G G C G G G C G C G C C G G G C C G C G C G G G C G C C C G G G G G G C C C C C C G C C C C C G C G G G G G C G G G G G G G C G C C G C G G C G G G C C G G C C G G G G G G G C G G G G G G G G C G C G C G G G G G G G C C G C C C G C G C C G G C G C G G G G C C G C G C C G C G G G G C C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T A A T A T T T A T T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T T T T A T A T T A T T T T T T T T T T T T T T T T A T A A T T A A T T T T T A T T T T A T T T T T T T T T T A T T T T T A A T T T T T T T T T T T T T T T T T A T T T T A T T T A T A T T T T T A T A A A T T T T T T T A T T T A T T A A T T A T T A T A A T T T T T A T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T +A T T T A A T T T T T T T A T A T T A T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A A T T A T A T T T T T T T A T T A A A A T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T A A T T T A T A T T T T T A T A T T T T A T A T T T T T T A A T A T T T T T T T A A A T A T T T A T T T T T T A T T T T T T T T T T T T T T T A T T T T T T A A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T A T T T T A T A T +G C G G G G C G C G C G G G G G C G G G G G G G G G C G G G C G G G G C G C G G G C G G C C G G G G G G C C G C G C G G G G G C G G G C G G G C G G G G G G G G G G G G G G G G G G G C G G G G G C G G C C G G G G G C G G G G C G G C G G G G G C G C G G G G G G G G C G C G C C G C G G G C G C G C G G G C G G G G G G G G G G G G G G G G G G G G G G C C C G G C G G G C G G C G G G G C G G C G G G C G G C C G G G C C C G C C G G C C G C G G C C C C G G G G G G C G G C G C G C G G G C G G C G C G C C C C C C G C G G G G C G G G G C G G C G G G G C G G G G G C +C G C C C C C C G C C C C C C C C C C C C C C C C C G C C C G C C C C C C G C C C G C C G G C C C C C C G G C G C G C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C G C C G 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T A T T A A T T T T T T A A T A T A T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T A A T T T T T A T T T T A T T A T T T T T A T T T T T T T T T T A T A T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A A A T T A T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T A T A T T T T T T T T A T A T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T A +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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C G G G G G G G C G C C G G C C G G C C G G G C G C C G G C C G C C G C G G G C C C C G C C G G G G G C G C G C G C G G C C G G C C C C C C G G C G G G G G C G G G G G G G C G G C G G C G G G G C G C C C G G G G G C G G C G C C G G C G C G G C G G G G G C C G C G G G C G G G G C G C C G G C G G C C C C C +A A A A A A A A A A A T T A A T A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A T T A A A A A A T T A T T A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A T A A A A A A A A A A A T A A A A A A A A A A A T A T A A A A A A A A T A A A T T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A T A A A A +T T T T T T T T A T T A A T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T A T T T T T T T T T T A T T A A T T A T T T T T A A T T A A A T T A T A A T T A T T T T T T T T T T T T T T T T A T T T T A T T T T T T A T A T T T T T T T T T A A T T A T T T A T T T T A T T T T T T A T T T T T T A T T A T A T A T T A T T T T T A T T T A A A A T T T A T A A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T A T T T A T A T T T T T T T T T T T T T T T A T T T T A A T A T T T A T A T A T T +G C G G G G G G C G G C C G G C G C G G C C G G G G G G G G G G C C G G C G C C G G C C C G G G G C G G C G G G C C C G C G G G G G G G C G G C C G G C G G G G C C C G G C C C C C C G C G G G C G G C G G G C G C C G G G G G G C C G G G C G G G G G G C G C G G G G G G G C G C C G C C C G G C G G G G C G G G G G G C G G C C C C C G C C C C G C C G C G G G G G C C G G C C G C C G G C G C C C C G G G G G G G G G G G G G G G G G C G G G G C C G G C C G G G C G G G G G C G G G G C G G G C G C G G G G G G G G G G G G C G G C G G G G C C C C G C C C G C G C G G +G C C C G G G C C G G G G G G G G C G G G G G G C G G G G G G G C G G C G G C G G C G G C C G G C G C G G G G G G G G C G G G G G G G G C G G C G G G G G G G G G G G G G C G G G G C C C G G G G G G C G G G G G C C C G G G C G G G G G G G C G C C C G C C G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G G C G G G G G C G G G G G G G C C G G G C G G C G C G C C G G G G G G G G G G G G G G C C G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G C C C G G G C G G G G C C G G G G G G C C G C C C G C C G G G C G G G C G G G G G G C C +A T A A A T T A A A A A A A A A T T A T A A A T A T A A T A A A T T A T A T T A A T T T T A T T A T T T A T A T T A T A T T A A A A A A A A A A A T A A A A T A A A A T A T A A T A A A T A A A A A T T A A A A A T T A A A T A A A A T T T A A T A T T A A A A T T T T T A A A A A A A T A A A T A T T T A A T A A A T A A T A T A T T A T T A T A A A T T T A T A A T A A A A A A A A T T A A A A A A A T A A T A A A A A A A A T A A A A T T A A A T A T T A A T A A A T A T T T A T A A A A A A A A A A T A A T T A T A A A A A T A T A A A T T A T A A T A T A T A A A A A +T A T T T A T T T T T T T T T T T T T T T T T A T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T A A A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G C C C G G C C C C C C C C C C C C C G C C C C G C C G G C C C C C C C C C C C C C C G C G C G G G C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C C G C C C C C G C C C C G C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C G C G G C C C C C G C C C G G C G C G C G C G C C C C C C C C C C G C C C C C C C C G G C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G G C C C G C C C C G G C C C C C G G G C C G C G G G C C C G C C C C C C C C C C C G +C G G G G G G G G G G C G G G C G G G G G G C G G G G G G G G G G C G G G G G C C G G G G G G C G G G C G G C G G G G G G G G G G G C G G G G G G G G G G C G G G G C G C G G G G C G G G G G G G G C G G C G G G G C G G G G G G C G G G G G G G G G G C G G G G G G G G G G C G G G G G G C G G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G G G C G C G C C G G G G G G +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A +G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G +G G G G G G C G G G C G G G C G C G G G G G G G G G G G G C G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G C G C G G G C G G G G G G C G G G G G G G G C C G G G G G C G G C C G C G G G G G G G G G G G G G G G G G G G G G C G G G G G C G C G G G C G G G G C G C G G G C C G G G G G G G C G G C G C G G G G G G G G C G C G G G G C G C G G G G G G G G 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T A A T T T A T T T A T T T A T T A T T A A T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T A T T T T T T T T T A T T T T T T T T T T T T A A +G C C G G G G C C C C G G C C G C G G G G C G C G C C G G G G C G G G C G C G G G G C G G G C C G G C G C C G C G C G G G C G C C C G C G C C G C C G C C G C C G G G G C C G G G G C G G C G G G G G C C G G G C C G G C G C G C G G C C C G G C G C C G G G G C G C C C G C G C G C C G G G C G C C C G G C G G C G G G G C G G G G C C C G C G G G G G C C G C C G G G C G G C G G G G G G C C C C C G C C G C G G G G G C G C C C G G C C G G C G C C G G C G C C G G C C C C C G C G G G C G G G G C G C G G C C C C C G G G C G G C G G G C G G G G G G C G G C G G C C G +C G G C C C G G G G G C G G G C G C C C C G C G C G G C C C C G G C C G C G C C C C G C C C G G C C G C G G C G C G C C C G C G G G C G C G G C G G C G G C G G C C C C G G C C C C G C C C C C C C C G G C C C G G C C G C G C G C C G G G C G G C G G C G G C G C G G G C G C G C G G 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T A T T T A T T T T A T A A A T T T T A T T T A T A A A A T A T A T T T T T T T T T A A A A T T T T A T T T T T A T A T A A T A A A T T T T T T A A T T T T T T A A A A T T A A T A A T A T A T T A T A T A T A T T T A A A T A T T T T T T T T A T A A A T A T A T T T A A A T T A T A T T T T T T T T T T T T T T T T T A A A T A T T A T T T A A T T T T T A A A T A A T A A A T A A A A A A T A A T T T T T A +C C G G C G G G G G G C G G C G C C G G G G G C G C G G G C G G G G G C G G G G G G C G G G G C G G G C G G G G G G G G C C G C G G C G C G G G G G C G C G C C G G G G G G G G G C G C C C G G G G G C G G C G G C G C C C G G G G G G G G G G G C C C G G G G G G G G G G G C G G G C G G C C C C C G G C G C C G C G C G C G G G G G G C G G G C C C C C G G C G G G G C G G C C G C G G G G C G G G G G C C G G C G C C C C C G C C C G C C C C G C C C C C G G C C G G C G G C G C G C G G G G G G C G C G C G G C G C C C G C G G G G G G G C G C C G G G G C C G G G G C +G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C C G C G G G C C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A 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C C C C C C C C C C C C C C G C G G G C G C C G C C C C C C C C G C C C C C C C C C C C C C C C G C C C G C G G C C C C C C G C C C C C C C C C G G C G C C C C C C C G C C C G C C C C C C C C C C C C G C C +G C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C G C C C C G C C C C C C C C C G C C C C G C G C C C C C C C C C C C G G C C C G G G C C C C C C C C C C C G C G C G C C C C C C C C C C C G G G C C C C C C C C G C C C C C G G C C C G G C C G C C G G C C C C C G C C C C C C G G C C C G C G C G G G G G C C G C C C G C C G C C C G C C C G C C C C C C G C C C C G C C C G C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C G C C G C C C C C C G C C C C C C C C C G C C C C C C C C C C C C C G +T T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T A T T T T A T T T T T T T T T A T T T T A T A T T T T T T T T T T T A A T T T A A A T T T T T T T T T T T T T A T A T T T T T T T T T T T A A A T T T T T T T T A T T T T T A A T T T A A T T A T T A A T T T T T A T T T T T T A A T T T A T A T A A A A A T T A T T T A T T A T T T A T T T A T T T T T T A T T T T A T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T A T T A T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T A +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C C G C C G C C C C C C C C C C C C C G C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C G C C C G G C C C G C C C C C C G C C C C C C C C G G C C C G C G C G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +C G G G G C G G G G G G G G G G G G G C C G C C C G C G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G C G G G G C G C G C C C G G G C C C G G C G C G G G G G G G C G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G C G G G G G G G C G G G G G C C C G G G G C G C C C G G G G G G C G G G G G G G G G C G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G C G G G G G G G G C C C C G C G G G C G G C C C G G G G G G G G C G C C G G C C G G G G G G G C G G G C G G C G +A T A T T T A T A T T T T T A T T A T T T T A T T T T T T T T T T T T A T T T T T T T A A A T T A T T T T T T T T T T T T T A T T T T T A A T A A T T T T A T T T T T T T A A A A T T T T A T T A A T T T A T T T T T A T A T T T T T T T T T A T T A A A A A T T T T T A T T A T T T A T T T A A T T A T T T T T T T T T A T T T T T T A A T T T A T A T A A T T A T A T T T A T T T A A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T A T T A T T T T T T T A +T A T T T T A A T A T A A T A T A T T T A A T A T T A T T A A T A T A T A A A A A A T T T A A A T T A A A A A A T T T A A A A A A A A A A T A T T A A A A A T A A A T A T T A A A T A T A A T T A T T A A A A A A A T T A T A A A A A A A A A A A A T T A A A A A A A A A A A T A A A A A A T A A A A A T T A A A A A T A A A T A A T T T A T A A T A T A A A A A A A A A A A T A A T T A T A A A A A A A A A A T T A A A T A A T A A A A T A A A A A A A A A A T A A A A A A A A A A A A A A A T T A T A T A A A A A T A T A A A T A A T T A A A T T A T A T A T A A A A A A T +C G C C G C G G G C G G G G G G G C G C G C G G G G C G C C C G C G C C C C C G G G G C C G C G G G C G C G G G G G G G C G G C G G G G G G C G C C C C G G G C C G C G G G C C G G C G C G G G G C G C C G C C C C G G G C C G C G C C C C C G C C C C G G G C C C C C C C C C C C C G G C G G G C G C C G C C G G C C G C G G G G G G C C G C G G C G C G C G G C C G C G G C C C G C G C G C G C C C C C C G G G G G C C C G C C C G G G G G G C G G C G G C C C G C C C C C C G G G G G G C G C G G C C G G G G C G C G C G G G G G G G G G C G G G C C G G C C C G G C G C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T T T T T A T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A A T A T T T T T T T T T T T T T A A A T T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T T A T T T T T T T A T T T T T T T A A T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T +A A A T A A T T T A A A A T T A T A A A T A T A T A A T A T A A A A A A T T A A T A T A A A T A T A A A A A A A A A A A A A T A A A T A T A T A A T A T A A T A T T A A A T A A A A T T A A A A A A A A T A T A A A A T A A T T T A T T T T A A T A A A A A A A T A T T A T T A A T A A T A A A A A A A A A A A A A T A T A A A A T T A A A T A T T T T A T A A T A A A A A T A A A T A A A A A A A A A T T A A A A T A A T A T A T A T A T T A A A A A T A A T A T T A T T A T T A T A T A T A A A T A A A A T A A A A A A A A T T A T A A T T A A T A A A A A A T A T A A A T +G C G C G G G C C G C C C C G C C G C G C C C G C C G C G G G C G C G G C C G C C G C G G C C C G C G C C C G C C C C C G G G G G G C C C G C C C C C C C G C G C C G C C G G G G C G C C C C C C C C G C G C G G C C G C C C C C C C C C C C C C G G G C C C C C G C C G C C G C C C C C G C C C C C G G G C G C C C G C G C C C C C C C G C C C G C G G G G G C G G C G C C G G G C C G G C G C C C C C C G C C C C G G C G C G C G C C C C G C G C G G G G G G C C G C C G C C C C C C C C C C G C C G G C C C C G C G C G C C C C C C C C C G C C C G C C G G G G C C C C C +C G G G C G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G G C G G G G G G C G G G G G C C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G +T A A T T A A A A A T T A T A T T A T A T A T A T T T T A A T T A T A A A A T T A A T A A T A T T T A T T T A T T T T A T A A A A A T A A A A A A A T A A A T A A T A T T A A A A T A T A A T T T A T A A A A T A T T T T A A T A T A A A A A T T A A A A A T A A A A A A A A A A A A T T T T A A A T A A T T A A T T A T A T T T T T T A A T A T T T T A A A A A A A T A T A A A T T A A A T A T A A T A A A A A T A A T T A A T A A A A A T T A A T A A T T A A A A T A A A A A T T T T A T A T A T T A A T T A A A A A A T A A T T T A T T T A A T A A A T A A A A T T A T A +T A A A A A A A A A A A A A A A A A A A A T T A T A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A A A T A A A T A A A A A A T A A A A A T T A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A A A A T A A +G G G G G C G G G G G G G G G G G C G C G G G C G G G G C G G G G G G G C G G G C G G C G C G G G G C G G G G G G G G C G G G G C C G G G G G G G G G G C C G G C G C G G C C C C G C G C G G G G G G G G C C G G C G C G C G G G G C G G G G G C G G G G G G G G C G G C G G C G G G G G G G G G G G C C G G G G G G C G C G G G G G G G G G G G C G C G G C C G C G G G C C C C G G C G C G C G G G G C G G G G G G C G G G G G G G G G C G G G G C G G G G G C G C G C G G G G G G G G G G G G G G G G C G G G G G G G G G G C G G G G G G G G G G C C G G C G G G G G G G G +G C C G G G G G G G C C G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G C G G G C G G G G C G G G C G G G G G G G G C C C G G C C G C G G G G G G G G C C G C C C G C G C G G G G G C G G G G G C G C G G G G G G C G G G G C G C G G G C C G C G G G G C G G G G G C C G G C C C G G C G G C G G G G G G C C G G G G C C G C G G G G G G G C G C C G C G G C G G G G C G G C G C G G C G G G G G C C G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G C G G G G G G C G G G G G C G G G G C G G G G G G G G G G G G C +A T T T A A A T A A T T A T A T T A T A T T T A T T A T A A A T A T T A A T A T A T T A T A T T T T A T A T A A T T A A A A T A A A T T T A T T T T T T A A T A T T A T T A T T T T T T T T T T T A T T T A A A T A T T A A T T T T A T T T T T T T A A T T T T T A T T T T T A T T T T T A T T T T A T A A T T A T T A T T T T A T T T T A T T T T T T A A T A T T T T A A T A A A T T A A T A T T T T A T A A T T T A A T A T A T A T A A T A A A A A T A A T A T A A A T A T T A T A T T T T T T T T A A A T T T A T A T A T A T T T T T T T T T T A A T T A A T A T T T T T +T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T A A T T A T T A A T T T T T T T A T T T A A A A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A A T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T A A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T A T T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G C C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C G C C C C C C C C C C G G C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C G G G C C C C C C G C C C C C C C C C G G C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C +T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T A T T T T +A T A T T T A T A A T A A T A T T T A T T A T A T T A T T A A T A A A T T T A A A T T A T A A T T T T A T A A T T T A T A T A A A A A T A A A A A T A T T A T T A T T A T A A A T T T T T A T T T A A A A A T T A T A T T T T T A A T T T T T T A T T T T T T T T T T T A A A A A A T A T A A T A T A A T T A A A A T T T A T T A T T A T A T A T T T T A T A T A T A T A A T T A T T A A A T A A A A A T T T A T T A A T T T A T T T A A T A A A T T A T A A T T T T T T T T T T A T A T T T A A A T T T T A T T T T T T T T T T T T A A T T T A T T A A A A A A A T T T T T T +C G G G G G G G C G G G C G G G G G G G G G G G G G C G G C C G G G C G G G C G C G G C G C C G G G G C G C C G G G C G C G C G C C G G G C C C G G G G G G G G G G G G G G C C G G G G G C G G G C G C C G G G C G G G G G G G C G G G G G G G C G G G G G G G G G G G C G C C G C G C G G G G C G G G G G C C C C G G G C G G G G G C G C G G G G G G C G G G G G C G C G G G C G G G G G G C G G G C G G G C G G G C G G G G G G G G C G G C C G G C G C C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C C G G G C G G C C G C C C C G G G G G G +C C C G G C G C C C G C G G G C G C C C G G G C G G C G C G C G C C G C G C C C G C G G C C C G G G G G G C C G G G G G C C G C C C C C C C C C C C G G G C G C C G C C C C G G C G C G C G G G C C C G G C G C G C C G G G C G C C G C C C G G G C C C C C G C C G C C G C G C C G G G G C C G C C C G C G G G G C G C G G G G C G G G C G G G G G G G G G G C G C C C G C G C C G G G G C C C C G G G G C C C G G C C C G C C C C C C C G C C C C G C C C C C C C G C G C C C C C G C G C G G C G G G C C C G C G C G C G C C G G G C G G G G G G G G G G C C G G C G G G G C +T A A T T A A A A A T T A T A A T A T A T A T A T A T T A T T T T T T A T T T T T T T A A T T T A T T T T T T A T A A T T A T T T T T A A A T A A T A T T A T A A T A T A A A A A T A T A A T T A T T T T A T A A A T A T A T T T T T T T T T T T T A A A A T A T T T T A T T T T A A T T T T A T T A A A T T T A T A A T T T T T T T A A A T A T A A A A T T A A A T T T T T A T T T A A T A T T A A T T T A T T T T T T T T A A T T A T T A T T A A T T A A T A T A T A T A T T A T A T T T A T T T T A A A T T T A T A T T T A T T T A T T T T T T A T A T A T T A T T A T T +T A A T T A T A A A T T T T A A T T T A T A A A A A A T A A T T T T A A T T A T T T T A A A A T T T A A T A T T T T T T T A A T T T T A A A T A T T A A T A T A A T A T T A A A A T A T T T T T A A T A A A T T A A T T T T T T T T T T T T T T T T A A A A T A T T T T T T T A T T A T T T T T A A A T A T A A T T T A T T T A A T T A A T T T T T T T T T T A T A T A A T T A T T T T T T T T T A A A T T T T T T A T T T T A A T T A T T A T T T T T T T T T A T T T T T T T T A T A T T T A T T T T T A A T T T T T T T T T T T T A T T T T A T T T T A A A T A T T T A T T +G C C G G C G C G C G G G G C C G G G C G G C C C G C G C C G G G G G C G G G G G G G G C C C G G G C G G G G G G G G G G G G G G G G C C C G C G G G C G C G C C G C G G C C C G G C G G G G G C C G G G C G G C G G G G G G G G G G G G G G G G G C C C C G C G G G G G G G C G G G G G G G G G C G G C G G G G G G C G G G C C G G C C G G G G G G G G G G C G C G C C G G C G G G G G G G G G G G G G G G G G G C G G G G C C G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G C G C G C G G G G G G +G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T T A T T A A A A A T A T A T A A T T T T A T A T T T T T T A A A T A T T A T T T A T T A A T A T A A T T T A A T T T T A T T T A T A T A T T A T T T A T T T T T A T A T T A A T A A T A A T T A A A A A A T A A A T A T A A A A T T T T T T T T T A A A T T T T T T A A T A T A A T A T A T T T T T A A A T A T T T T A A T A T T T T A T A A T A T T T T T T T T T T T T T T T A A A T T T A T A T T T A A A T T T A T T T T T T A A T T A T A T T T T T T T A T A T T T T T T T A T A T A T A A T T T A T A T A T A T A A A A T T A A T A A A T T T T T T A T T A T T T +T T T T T A T T T T T T A T T T A T T A A A A T A T A A A T A T T T T A T T A T T T T T T T T T T T T T T A A T T T A T A A T T T T T A T A T A A T A A T T T A A A A T T T A A T T A T T T T T A T T T T T A A T T T T T A T T T T T A T T A A T T A A T T T A T T T T T T T T T A T T A T T T A A A T A T T T T T A A A T T T A T A T T T T T T T A T T A T T T A T T A T T A T A T T A T T A A T A T A T T T T T A A T A T A A T T A T T A T T T T A T T T T A T T A T A T T T A A A T T T A T T T T T A A T T T T T T T A T T T T A T T T A T T T A A T A A T T A A T T T T +G G G G G C G C G C G G C G G C C C G C C C C C C G C C C G C G G G G C G G C G C G G G G G G G G G G G G C C G G G C G C C G G G G G C C C G C C G C C G C G C C C C G G C C C G G C G G G G G C G G G G C C C G G G G G C G G G G G C G G C C G G C C C C C C G G G G G G G C G C G G C G G G C C C G C G G G G C C C C G G G C G C G G G G G G G C G G C G G G C G G C G C C G C G G C G G C C G C G C G G C G G C C G C G C C G G C C G C G C G G C G G G G C G G C G C G G G C C C G C G C G G G G G C C G C G G G G G C C G G G C G G G C G G G C C C C C G G C C G G C G +C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T A T T A T T A A A A A A A T A A A A T A A A A A A A T T A A T A A A T A T A A A T T T T T A A A A A A A A A A A A T A T A A T T T A T A T A T T A T A T A A A A A T A A A A A T A T A A A A A T T A A A A A T A A A A T T T A A A A T T T A A T T T T A A A A T T T T T A A A A T A A A A T A A A T T T A A A A A T T A A A A A A A T T A A T A A T A T A T T T T T T A T A A T T T A T A A A A A A A A T A A A A A A T T A A T T A A A A T T A A A A T A A T T T A T T A A T T T A T A A A A A T A A A T T A A A A A A A T A A A A A A A A A A A A T T A T A A A T A A A A T +A A A T T T A T A T T A A A A T T T T A T T A T A T T A A A T T T T T A T A T T T A A T A A T T T T T T A T A A T T A A A T T A A A A A T A T A A T A T A T A T T T A A T T T T A T A T T T T T A A T T T T T A T A T T A A A T T T T A A A T T A A A A T T T T A A A A A T T T T A T T T T A T T T A A T T A T T T A T T T T T T T T A T T T A T T A T T T A A A A T A T A T T A A A A A T T T T A T A T A T T T T A T T A A T A A A T T T A A T T T T A T T A A A T A A T T A A A T A T T T T T T T T T A A T T T T T T T A T T T T T T T T T T T T A A T A T A T A T T A T T +G G C C C G G G G G C G G G G G G G G G C G C G C G G G G G G C C C C G G G G G G G G G C G C C G C G C G G G G C G G G G G C G G G G G G C C C G C G G G G G C G C G G G G C G G C G G G G C C G G C C C G C G G G C G G G G C C C G G G G G G G G G G G G G G G G G G G C C C C G C G G C G G G G G G G C G G G G G G C C C C G G G G C G C G G G G G C C G G G G C C G G G G G G G G G C G G G G G G C G G G C C C G C G C G G G C G G C G G G G G G G G G G G G G G G C G G G G C G C G C G C G C C G G G C G C G C G C G G G C C G C C C C G C C G G C G C G G G C G G G C +G G C C C G G G G G C G G G G G G G G G C G C G C G G G G G G C C C C G G G G G G G G G C G C C G C G C G G G G C G G G G G C G G G G G G C C C G C G G G G G C G C G G G G C G G C G G G G C C G G C C C G C G G G C G G G G C C C G G G G G G G G G G G G G G G G G G G C C C C G C G G C G G G G G G G C G G G G G G C C C C G G G G C G C G G G G G C C G G G G C C G G G G G G G G G C G G G G G G C G G G C C C G C G C G G G C G G C G G G G G G G G G G G G G G G C G G G G C G C G C G C G C C G G G C G C G C G C G G G C C G C C C C G C C G G C G C G G G C G G G C +T T A T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T +A T T T T T T A T T T A A T A T A A T A T A T A T A A A A A A T T T T A T T T T A A T T A A T T A T A T T A A T T A T T T A T T T T A A T T T T T T T A A A T T A T A T T A A A A T A A T T T T A A T A T A T A T T T A A A T T T T T A T T A A A T A A T T T A T T T T A T T T T T T A T T T A T A A A T T T A T A A T A T T T T T T A T T T T T A A A T T A A A A T A T T A A T T T T T T T A T A A T T T T T T T T A T A T T A T T T T T A T T T A A T T T T A T A T T T T T T A T A T A T A T T T T T A A T A T T T T T A A A T T T T T T T A T T T T T A T A T T T A T A T +G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G +C C C C C C C G C C C C C C G G G G C G C C C G C G C G G C C C C C C G C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C C G G C C C C C G C C G C C C C G C C C C C G C G C C C C C G G C C C G C C C C C G G C C C C C C G C C C C C C G G G G G C C C C C C C C C C C C G C C C G C C C C C C C C C G C C C C C C C C C G C C C C C G C G C C C G C G C C C C G G C C C C C C C C C C C C C C C G C C C C C C C C G C C C G C C C G C C C C C C C G C C C C C C C C C C C C G C C C C C C C G C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C G C G C +T T A T T T T T T T T T T T T A A T T A T T T T T A T A A T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T A A T T T T T A T T T T T T T A T T T T T A T A T A T T T A A T T T T T T T T T A A T T T T T T A T T T T T T A A A A A T T T T T T T T T T T T A T T T A T T T T T T T T T A T T T T T T T T T A T A T T T A T A T T T A T A T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T A T T T A T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T +T A A A A T A A A A A T T T A T A A A T A T T A T T T A T A T A A A T T A A A A A A T A T T A A T A A A T T T T A A T T T T T T T T T T T A A A A A T A T A A T T A T A A T A T T A T A T A A A T T A A T A A A T A A T T A A A A T A T A T T T T A T T T T T T A A A A A A A A A T T T A A T T A A A A T A A T A T A A T A A A A A T T A A A T A T A T A A A T A T A T A A A T T A A T T A A T A A T A A A A T T A T T A A T A T A T A T A A A T A T A A A A A T A T A A A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A T A A A A A A T T A A A A A A A A A A A +C G G G G C G G G G G G G G G G C C G C G G C G C G G G C G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G C G G G G C G G G G G G G G C G G G G G G G C G G G G G G G G G G C G C C C G G C G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +T T T T A A T T T A T T T T T A T A A T T T A T A A T T T T T A T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T A A T A T T T T T T T A T T T T T A A A T A T T T A T T T T T T T T T T A T T T T T T A T T T T T T A A T T T T A A A A T T T T T T T A T T T A A T T T A T T T A A T T T A A A T T T T T A T T T T A T A T T A T T T T T T T T T A T T T A T T A A T T A T T T T T T A T T T T T T T T T T T T A A T T A T T T T T T T T T T T T T T T T T T T A T A T T T T A T T T A T T T T T T T T T A A A T T A T T T A T T A A A T T T T A 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T T T T T T T T T T A T T T T T T T T A T A T T T T T T A T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T A T T T +A T A A T T T T A T T T T T T T A T T A T A T A T A T T A T T T T T T A T T T T A T T A A A T T T T A T T A A T T T T A T A T T T T T A T T T T T T A A T A T T T T A T A T A A A T A A T A T T A T T T T A T T A T T T T A T T T T T A T A T T A T T T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T A T A T A T T A A T T T A T T T T T T T T T T T T A A T T T A T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T A T T A T T A A T A T A T A T T T T T A T T T A T T T A A T T T T T A T A A +C C G C C G C C C C C G G G C G C G G C C C C C C C G G C G G C G C G C C C C C C G G C C C C C G C C C C C C C C C C C G C C G G G G C G G C G C C C C C C C C C C C C C G C C C C C C C C 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T A T T A T T A A A T A A A A T A T A A A A A T T T T T T A A A A A A T T A A A T A T A T A T A A A A A A A A A A A A A T A T T A T T A A A T T T A A T A T T T A A A T A A A A T A A A A T T A A T T A T T T T T A A A T T T T A A T T A A A A A A A A A A A A A T A A T A A T T A T A A A T T T A T A A +G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G C C G G G G C G C G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G C G G G G G C G G G G G C G G G G C G G C G G G G G G G G G G G C G G G G G G C G C G G C G G G G G G G C G G G G G G G G G G C G G G G G G G G C G G G C G G G C G C G G C C C C G G G G G G C G G G G G G G G G G G G G C G G G G G C G C G G G G G G G G G G G G G G G C G C G G G G G G G G G +C C C C C C C C C C C C C C C C G C G C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C G C C C C C G G C C C C C C C G C C 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A A A T A A A A T T T T A A A T A T A T T T T T T T T T T A T A A T T T A T T T A A T A A A A A T A A T T T A A A A T A A T A T T A A A A T A T T T A A A T A A A A A T A A A A T T T T A T T A T T T A A T A T T T T T T T T A T T A A A A T T A T T A T T A A T A A A A A A T A A T T A T A T A T A A T T T T A T T A A T T A A A A A T T A A T A T T T T A T T A T A A T T T T T A T T T A T A T T T T T T T T T T A A T T A T T T T T T T T T T T T T T T T T T T A T A T T T A A T T T A T T T T T T T T T A A T A T A T T T A A A A T T T T A T A T T A +C G G C C G G G G G G C G C G C C G G G G G G G G G G C G G G G G G G G C G G G C G C C C C G G G G C G G G C G G G G G G G G C C C C G G G G G G G G G G G G G G G G C G G G G G C G G G C G G C G G G G G G G C G G G G C G C G G C G G G G G C G G G C C C G G G G G G G G C G G G G G G C G G G G G G C G G G C G C G G G G G G C C G C G G G C C G G G G C G G G C G G G C G G G G C G G G G G G G G G G C G G G G G G G G G G G G C G G G C G G G G G G G G G G G G 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A T T A A T T T T T A T A A T T A A T A T A A T T T T T T T T T T A A A T T A T T T A T T A T T T T A T T T T T T T T A T T T T T T T T T A T T A T A T T T T T A T T T T T T A T T T T A T T T T A A A T T T T T A A T T A A A +T T A T T A T A T A A T A T T T T A T T A A A T T A A T T A A A T A T T A T A A T T T T T T A A T A T A A A A A A T A A A T A T T T T T T T A T A A T A A T A A T A T T A A A A A T T A A T T T T A A A T T A A T A A A A A A T A A A T T T A A T T A A T T T A T A T T A A A T A A T A A T T T A A A A A T A A A T A T A A A A A A T T A T A A A T T A A A A T A T A T A A T T T A A A T A A A A A A A A A T T A A A A A A A T T A A T T A A A T T A A A T T A T A T T A A T A A A A A T A T A A A A T T T A T A A T A T A A A T T T A A A T A A A A A T A A A T A A A T A A A +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C 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T A T T A T T T T A T A T T A A A T T T T T A A A A A T T T T T T A A T T T A A T A T A T A A T A A A A A T T A T T T A A T T A A T A A A T A T A A A A T T T T T A A T A A T A A T A A T T T T T A A T A T T T T A T T T T A T T A T T A A T T A T T T T T T T A T T T T T T T A A A T T A A A A A T T T T T A T T A T A T T T T T T A T T T T T A T T A A T T T T T A A A A T T A A A T A T A T T T A T A T T A T A T T T T T T A T A A T T A T A T A T A T A T A T T A T T T A T +T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T A T T A T A T T T T T T T T T T T A T T T T A T T T T T T T A T A A A A A A A A T T T T T T T T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T A T T A T T T A T T T T T T T T T A T T T A T T T T T T A T T T T T T A T T T T T T T T T T T T T T A T T T T T T T A T +G G G G G G G C G G C G G G G G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G C G G C G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G C G G G G G G G G G G G G G G G G G C C G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G C G G C G G G C G G G C C G G G G C G G C G G G C G G G G G G G C C G C G G G G C G C C C C G G G C G G G G G G G G G G G G G G G G G G C G G G G C G G G G C C G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C C C G C G G +C C C C C C C G C C G C C C C C C G C C G C C C C C G C C G C G C C C C C C C C C C C C C C G C C G C G C C C C G C C C C C C C C C C C C C C C C G C C G C C C C G C C G C C C C C C C C C C C C C C C C C G G C C C G G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C G G C C G C C G C C C G C C G G G C C C C G C C G C C C G C C C G G C C G G C G C C C C G G G G 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T A T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C G G C C G C C C G C G G G C C C C C C G C G G G G C C C G C C C C C C C C C G C C C C C C G C C C C G G C G C C G G G C C G G G G G G C C C C C G C G C G G G G G C C C G G G G G C G C C G G C C C G G C G G C G C C C G C G C G C C C C C C G C G G C C C C C C C C C C C C G C C C G G G C C G C G G C G C G C C C G C G C G C G C C G G C C C C C C G C C C G C C G C C C C C G C G C C G C G G G G C C C C C C C G G C C C C C C C G G G C C C C G C C G C C G C C G C C C G G G G C G G C G C G C C G G C C C C C C G C G G G C C C G C C C C C C G G C C C C G G C C G +G G C G C G C G C G G G G G C G G C C G G G G C C G C G C G C G C G C C C C G G G C G C G G G G G C C G C G G G C C C C C G G G G G G G C C G C G G G C G C G G G G C G G G G G G C G G C G C C G G G G C C G G C G C G G C G C G G C C C C G G G C G G C C C G C G C C G G G C G G C G G G G C G C G G G C C C G C G C G C G G G G C G G G G C G G G G G G G C G G G G G G C G C G G C G C C G G G G C G G C C C G C G G G C C C G G C C C G G C C C C G C C G C G G G G G C G G G G G C C C G G G G C C C C G C C C C C C G C G C C G G C C G C C G G C G G G C G G G G C C G +T T A A T T T A T T A T T T T A T T T A T T T A A T T A T T T A T A T T T T A T T T A T T T T A T T T T A T T A T A A A T A T T T T T T T T A T A T T A A A T T T T T A A T T T T A T T T T A A T A A T A T T T T T T A A A A A A T T T T T A A T T T T T T T A T A T T T A A T T A T A T T T T A A T T T T A T T T A T T T T A T A A A A T T T A T T A A T T T T T A T T A T T T A T T T T T T A T T A T A T T T A T A T T T T T A A T T A T T T T T T T T T T T A T A A T T A A T T T A T A T A T A A T T A T T T T T T T T T T A A A A T A A T T A A T T T A T A A T T T T T +A T A A A T A A A A A T T T A A A T A A T A A T T A T A A T T A A A A A A A A T A A A A A A T A A A A T A A T A A A A A T A T T T T T A A A A A A T A A A T A T T T A A A A A T A A A A T A A A A A A A T A T T A T A A A T A T A T A A A A A A T A T T A A A A A A A A A A A A A A A A T A T A A A A T T A A A A A A A A A T A T A T A A A A A A A A A A T A A A A A A T A A A T A A T A A A T A T T A T A A A A A T A T T A A A A A A A A T T A A A T T A A T A A A A A T A A A T T T T T T T A A A T A A T T T A A A A A T T A T T A A A T A A A A A A A T A A A A T T A T T +C G C C C G C C C C C G G G C C C G C C G C C C G C G C C G G C C C C C C C C G C C C C C C G C C C C G C C G C C C C C G C G G G G G C C C C C C G C C C C C G G G C C C C C G C C C C G C C C C C C C C C G G C C C C C C C C C G C C C C C C G C G G C C C C C C C C C C C C C C C C G C G C C C C G G C C C C C C C C C G C G C C C C C C C C G G C C G C C C C C C G C C C G C C G C C C G C G G C G C C C C C G C G G C C C C C C C C G G C C C G G C C G C C C C C G C C C G G G C G C G C C C C C C C G G C C C C C G G C C C C C C C C C C C C C C G C C C C G G C G G +C C C G C C C G C C G C C C C G C C C G C C C C C C C G C C C G G G C C C C G C C C G C C C C C C C C C C C C G C C C C C G C C C C C C C C C C G C C C G C C C C C C G G C C C C C C C C C C C C G G G C C C C C G C G G C G C C C C C C C G G C C C C G G G G C G C C C C C C C C G G C G C G G C C C C C C G G G G C C C C C C C C G G G C C C C C G G C C C C C G C C G C C C G C C C C G C G C C C C G C G C G C G C C C C C G G C G C C C G C C C C C C C C G C G G C C G G C C C C C C C G C G C C C C C C C C C C C C C C C C G G C C G C G G G C C C G C G G C C C C C +A A A A A T T A A A T T T T T T A A T A T A A A A A A A T T A A A A A T A T A T A A A A A A T T A A A T A A A A T A A A A A T T T T T A T T T T T T A A T A A A A T T A A A A A A A A A T A A A A A A T A A T T A A A A T A T A T A A T T T A A A T T A T T T A T A T T T T T A A T T A T A T T A A T A T A A T T T A T A A T A T T A A A A A A T A T A A T T A T A A A T A A T A A A A A A A A A T T A T T T T A A A A T T A T T T A T T A A A T T A A A T T A T T A A T T T T T A T A A A A T T A A A T T A A A A T A T A T A A A A A A A A A A T A A A A A A T A A T A A A T +A A A T A A A T A A T T T T A A A A T T A A A A A A A T T A A T A T A T A T T A A A T A T A A T A A A A A A A T A A A A A T A A A A T A A A T A A A A A A A A A A A T T T A A A A A T A A A A A A T T A A A A A T T A T A A A A T A A T A T T T A A A T A A A T A T A A T T T A A T A A A A A A T A T A A A A A A A A A A A A A T T A T T A A A T A A T T A T A T A T A A T A T A A A A A A A A A A A A A A A A A T A T A A A A T A T A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A A T A A T A A A A A A A A A A A A A T T A A T A A A T A A A T A A T A A A A A +G C C C C C C C C G C C G C C C G C C C C G G C C G C C C C C C C C C C C C C C C C C C G G C C C C C C C G C C C C C C C C C C C C C G C C C C C C G G C C G C C C C C C G G C G C C G C C C C G C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C G C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C G C G G C G C G C G C C G C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C G C C +C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T A T T T A T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T +T A T A T T A A T A A A A A A A T T T A T A A A T A T A T T T A A A T T T A A T T A A T A T T A T T T T T A T A A T T T T A A A A A A A A A A A T T A A A A A A A T T T T A A A A T A A T A T T A A A T A T T T T A T A A T T T A T A T A T A A T A T A T T T A A T A A A A A T A A T A T A A T A T A A T T A T T T T A T A T T A A T A A T A T A T T A A T A T A A A A T A T A T T A A A A T T T T T T T T T T A T T A T T A T T T A T T T A A T T A T A T T A T T A T T T T T T A T A T A T T T A T T T T T A A A T A T A T A A T T A A A T A A A A A T A A A A T A T T T A T +G C G G G G C C G C G C C C C C G G G G G C C C G C G G G G G G C G G G G C G G G C G G C G G C G G G G G C G G G G G G G G C C C C C C C C C C G G C C C C C C C G G G G C C C C G C C G C G G C C G G C G G G G G G G G G G G C G C G C G G G G C G G G G G G C G C C C C C G C C G G G C C G G G C C G G G G G G G G G C G G C C G G G G G G C G G G G G C G C C C C G C G C G G C C C C G G G G G G G G G G C G G G G G C G G G G G G G C C G G G G C G G C G G C G G G G G G C G C G C G G G C G G G G G C C C G C G C G C C G G G C C G G C C C C G C C G C G C G G G C G +G G C G C C G G C G G G G G G G G C C G C G G G C G C G C C C G G G C C C G C C C C G C G C C G C C C C C G G G G C C C C G G C C C G G G G G G C C G C G G G G G C C G C G G G G C G G C C C C G G G C G C C C C G C G G C C C G C G C G C G G C G C G C C C G G G G G C G G C G G C G C C C C G C C G C C G C C C C G C G C C G G C G G G G C G C C G G C G C C G G G C G C C C C G G G G C C C C C C C C C C G C C G C C G C C C G C C C G G C C G C G C C G C C G G C C C C C G C G C G C C C G C C C C C G G G C G C G C G G C C C G G C G G G G G C G G C G C G C C C G C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +A A T A A T A A A T A A T A A A A T T T T T T T T T T A T T T A A A A T T A T T A T A A T T T T A A T T T T T A A A T T T A T A A A A T A A T A T T A T A T T T T T T T A T T T T A T T T T A A T A A T T A T T T A A A A T T T T T T T A T A A T A T A T T T A A A A A T T T A T T T A T T A T A T T A T A A T T T A A T T T T T T T A A A A T T A A A A T T T T T A T T A T T A T T T T T T T A T T T T T T T A A T A T T A T T T A T T T A T T T A T T T T T T T T A T T T T T A T A T T T T T A A T T T T A T A T A T A T T T T T T A A T A A A A T A T T T A A T T T T T T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G C G G G G G C G G G C C G G G G G G G C G G G G G G G G G G G G G C G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G +G C G C C C C C C C C C C C C C G C G C C C C C C C C C G C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C +A T A T A A A T A A T T A T A A T A A A A A A A T A A T A A A T T T A A A A A A A A T A A A A A A A T A A A A T T T T T T T A T A A T A A A A A A A A A T A A A A A A A T A A A A T A A A A T T A T T T A A A A A T T T T A A A A A A A A A T T T A A T A A A T A T A A A A A T A A A T A A A A T A A T A A T A A A A T A A A A A A A T T T T A A T T T T A T A A A T A A A A A A A A A A A A A T A A A A A T A T A A T A A A T A A T T A T T A A T A A A T T A A A A T A A T A A T A T A A A A A T T A T A A T A A T A T A A A A A A A T A A T T A T A T A A A A T A A T A A A +T A T A A A A A A T A A A A A A T A T T A A A T A T A A T A A A T A A T A A T A A T A T T A A T A A T A A A T A A A T A A A A A A A A T A A T A A A A T T T T A T A T T T T A T A A A T A A A A A T T T T A A A A A T T T T A T T A A A A T A A T A A A T T T A A A A A T T T T T A T A A T A T A A T A A A A A A T T A A T A A A T T T A T A A T T T A A A A T T T A A A A T T A T T T T A A A A A A A A A A T T T A A A A T A T A A A T T A T T A A A T A A T T A T T A A A A A A A A T T T A T A T T A T T A T T A T A T A T T T T T A T T A T A A T T A T T A A T A T T T A +G C G C G G G G G G G G G C G G C G G G G G G C G G C C G G G C G C G G G G G G G C C G C G G G G G G G G G G C C C C G G C G C G G G C G G G G G G G C C C G G C G G G C G G G G C G G G C C C G G G G C G G G C C G G C G G G G G G G G G C C G G G G C C C C G C G G C G G G G G G C G G G C C G C G G G C G G C G C G G G G C G C C C G C G G G G C G G C C C C C G C G C C G G C G C G G G G G G G G G G C C G G C G G G G G G C G C G G G C G G G G G G G G G G C G G G G G G G G G G G G G C C G G G G G G G G G G G G G C G G G C G G C C G C C G G G G G C C G C G G G +G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G C G G G G C G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G +A A T T T A T T T A T T T T T T T A A T A T A T A A A T A A T T T T T A A T A A T T T A T A T T T T T T A T A T T T T A T T T A T T T T T T T T T A T T T A A A T A A T A A A A A T A T T T T T A A T A T T T A T T T T T A A T T T T A T A T T A T T T T T T T T A T T T T T T T A T T A T T T T T T T A T T A T T A T A T A T T T A T T T T A T A A T T T T T T T T T T T A T T T T T T T T T A A A A A A A T A T T T A A T A A A T A T A T T T A T T T A A T A A T T A T A A A T A T T T T A T T A T A A T T T T A T A T A T T T T A T T T T T T T T T A A A T T T A T T T A +T T A A T T T T T A T T T A T T A A A T T T A A A A A A A T A A T A A A T T T T T A A T A A A T A T T A T T A A A T A T A A T T T T T A T T T T A T T T A A A A T T A T A A T A A T A T T T T T T A T T A A A T T A T T A T T T T T T T T A A A T T A A A A A A T T T T T T T T T T T A T A T A A T T T T T A T A A T A T T T A A T A T T T A T T T T A A T A T T A A T A T A T T T A T A T T T T T T T T T T A A T T A T T T T A T A T A T T T A T T A T T T T A T T A T A T T T T T T T T T T T A A T T A T T T T T T T T T T A T T T A T T A A T A T T T A T T A A T T T T T +G G G G G C C C G C C C C C C G C G G G C G G C G G C C G C C C G C C G G C G C G C G G C C C G C C G C G G C C C G C G G G G G G G C C C G G C C C G C C C G G C C G G C C G G G G C G G C G G G G G G C C C C G C G G C G C G G G G G C G C C G C C C C C C C C G C C G G G G G G G C G C G C C G G G C G C G C C G C C G G C C C G G G G C G C G G C C G C G G C C G C C C G C G G G C G G G G C C G C C G C C G G C C C G G G C C G C G G G C G G C G G G G G C G C C C G C C G C G G G G C G C C G G G G G G G G G G G C G C G G G C G G C C G C G G G G G C C G C C G G C +C G G G G G C G C G G C G G C G C C G C G C G C G G G G G G G G G G G G C C C G C G G C C C G C G G G G C C G G G C G C C G G C G G G G C G G G G G C C C G G G C G G C G G C G G C C C C C C C C C G C C G G G G G G G G G G C C G C C C G G G C C G G C C C G C C C C C C C C C C C G G G C G G C C C G G G C G C G G G C C G G G C C G G G C G C C G G G G C C C G C G G C C G C G C C C C G C G G C G G C C G C C G G G C C G G G C C C C G C C C G C G C G G G C C G G C G G C G C C C C G C G G C C G C C C C C C C C G C C C C C G C C G C C G G C C G C C G G G C C C G +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T 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C G C C C G C G C C G G C C G C C G C C C C C C C C C C C G C C G C C C C C G C C G C G C C C C C G C C G C C C C C C C C C C G C C G G G C C G C C G G C G C C C C C C C C G C C C C C C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C G C C C G C C C G C C C C C C C C C C G C C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G G C G G C G G C C C C C C C C C C C C C C C C C G C C C C C C G C C C G C C C C C C C C C C C C C G C C C C C G C C C +G C C C G C G C G C C C C C C C G C C C C C C C C C C C C C C C C C C G G C C C G G C G C C C C C G C G C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C G C C C C C C C C C G C C G C C C C C C C C C C C C C C C G C C G C G C C C C C C C C C C C C C C G C C C C C G C C C G C C C G G C G C C C C G C C C C C C G C C C C C C C C C C C C C G G G C C C G C G C C C C C C C C C C C C C C C C C G C C C C C G G C C C C C G C C C C C G C C C C C C G C C C C C G C G C C C C G G C C C C C G C G G C G G C C G C C C C G C C C G G C C C C C C C C C C C C C +A A T A A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A T A A A A A A T A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T A A A A T A A T A A A A A A A A A A T T A A A T A A A A T A A A A T A A A A A A A +T T T T A T A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T A T T T A T T A T T T T A T T T T T T T T T T T T T T T T T T T T A A T T T T T T A T T A T T T T T T T T T T T A T T T T T T T T A T T T A T T T T T A T T A T T A T T T A T T A T T T T T T T T T T T T T A T T T T T A T A T T T A T T T T T T T T T T T T T T T T T T T T T T T +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C G C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C +C C C C C C C C C C C C C C C C C G C C C C C C G C C G G C C C C C C C C C G C C G C C C C C C C G C C C C C C C C C C C C C G C C C C C G G C C C C C C G C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C G C C C C C C G C C G C G C C G C C C C C C C G C C C C C C C C C C C C C C G G C G G C C C G C C C C C C C C G C C C G C C G C G C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C G C C C C C G C G C C C C C C C C C C C C C G C C G C G C C C C C C C C C C C C C G C C C C C C C G C C G C C C G C G C C C +A A T T T A T T T A T T A T A T T A A T A A T T T T T A A A A A A T T T T A A A T T T T T T A T T T A T A A T A T A A T T T A A A A T T A T T A A A A T T T T T A A A T T A T T T A A A T A A A A A T T T T T A A A A T T T A A A T T T A T T T A A T T T T T T A T A A T T A T A A T A T A T A T A T A A T A T T T T A T T A T T T T T T A T A T T T T T A A T T A A T T T T T T T T A T A T T A A A A A A T T T T T T A A T T T A T T T T A T T T T T T T T T A A T T A T T A A A A A A T A A T A T A T A A A A T T T T T A T T A A A A T A A T T A A T A A T A T A T T T T T +T T A T A T A T T T T T T T T A A T T T T T T T A T T T T T T T T T T T T T T T A T T A A T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T A T T T A T T T A T T A T T T T A T T T T T T T T T T T T T T T T T T T T A A T T T T T T A T T T T T T T A T T T T T T A T T T A T T T T A T T T A T T T T T A T A A T T A T T T A T T A T T T T T T T T T T T T T A T T T T T A T A T T T A T T T T T T T T T T T A T T T T T T T T T T T +C C C G G C G C C C C C G C C G C C C C C G C C G C C G C C G C C C C C C C C C C C C G G C C C C C C G G C C C C C C C C G G C G G C C C C C C C C G C C C C C C C C C C C C C C C G G C G C C C G C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C C C G G C G C G C C C C C G G G G C C G C C C C G C G C C C G C G C C C C C C G C C C C C G G C C C C C C C C C C C C G C G G C C C C C C C G C G C C C G C C C C C C C C C C C G G C C C C C C C G C C C C C C C C C C C C C C C C C C C C G G C G C G C C C C C C G G C G C G G G G G C C C C C C C C C C +C G C G C G C G G G G G C G G C C C G G G C G G C G G G G G G G G G G G G G G G C G G C C G G G G C G C C G C G G G G G G G G G G G G G G G G G G C C G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G C G C G G C G G G C G G G C G G G G G G G C G G G G G G G C G C G G G G G G G G G G C C G G G G G G C G G G G G C G C G G G G G G C G G G C G G G G C G G G C G G G G G C G C C G G C G G G C G G C G G G G G G G G G G G G G C G G G G G C G C G G G C G G G G G G G G G G G C G G G G G G G G G G G +T A T A A A T T A A A A T A T A T T A A A T T T A T A A A A A A A A A T A T A A T T A T A A A A A T A T T A T A T T A T A A A A A A A A T A A A T T T T T T A T T A A T A A T T T T A A A A T T A T A T A T A A T A A T T T A T A A A A T T A A A T A A A A A A T T T T A A A A A A T A A A T A A A A A A A A T A A A A A T A A A T T T T A T A T A T A A A A A A A A A A T A T A A T A T T A A A A A A A A T A A A A A A A A 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+C G C G C C C C G C C C C C C C C C C C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C G C C C C C C C C C C C C C C C G C C C C C G C C C C C G C C C C C C C C C C C G G C C C C C C C C G C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C G C C C C C C C G C G C C C C C C C C C G G C C G G G C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C G G C C G C C G G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C +T T T T T T T T T T T T A T T T T T T T T A T T T T T T T T T A T T T A T A T T T A T T A T T T T T A T A T T T A T T T T T T T T T T T T T A T T T A A T T T T A T T T T T T T T T T T A A T T T T T T T T T T A T T T T T T T T T T T A A A A T A T T T T T T A A A A T A T A T T T T T T T T T T A T T A T T T T A T T T T T T T T T T T T T T T T T T T T A A A T T T T A T T T T T T A T T T T T T T T T T A T T T A T T T A T T T T T T T T T T 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C G C C G G G G C G C C C C C C G G G C C C C C C C C C G G C G C C C C C C G C C G C C G C C C G C C C C C C G C C C C C G C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C G C C G G C C G C C G C C C C G G C C +A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A T A T T A T A A A A A A T A T T A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A A A A +T T A T T T A A T T A A T T T T A A T T T T T A T T T T T A T T T T T T T T T T A T T T T T T T T T A T T T T T T T A T T T T T T T A A A T A A T A T T A A T T T T A T T T A T A T T T T A T T T T T T T T T T T A T T A A A T A A T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T A T T A T T T T T A T T T A T T T T T T T A T A T A T T T T T A T T T T T T A A T T A T T A T T A T T T A A T T T T A T T T A T A T A T T T T T A T A A T T A A A T A A T A A A T T T T T T T T T T T A A T T T A A T A T T T A T T T T T T A T T T A T T T T T A T T T T T T +G G C G G G C C G G C C G C G G G C C G G G G G G G G G G G G C G C G G G G G G C C G G G G G G C G C G G G G G G G C G G G G G G G C C C G G C G C G G G C G G G G G G G G C G C G G G G C G G G G C C G G G G C C C G C C G G C G G G G G G G C G G G G G G G G G G G C G G G G G G C G G C C G C G G C G G G G C C G G C C G G G G G G G C G C G C G G G G G C G G G G G G C C G G C G G C G G C G G G G C G G G G C G G G C G G G C G G G G G C G C C G G C G G G C G G C G G G G G G G G G G G G G C G G G G C C G C G G G C G G G G G G C G G G C G G G G G C G G G G G G +C C G C C C G G C C G G C G C C C G G C C C C C C C C C C C C G C G C C C C C C G C C C C C C C G C G C C C C C C C G C C C C C C C G G G C C G C C C C C C C C C C C C C C G C G C C C C G C C C C G G C C C C G G G C G C C C G C C C C C C C G C C C G G G C C C C C G C C C C C C C C C G C C G C C G C C C C G G C C G G C C C C C C C G C G C G C C C C C G C C C C C C G G C C G C C G C C G C C C C G C C C C G C C C G C C C G C C C C C G C G G C C G C C C G C C G C C C C C C C C C C C C C G C C C C G G C G C C C G C C C C C C G C C C G C C C C C G C C C C C C +A A T A A A T T T A T T A T A T A T T A A A A A A A A T A A T T A T A A A A A A T A A A A A A A T A T A A A A A A A T A A A T A T T T T A A A A A T A A A T A A A A A A A T T A T A A A A T A A A A T T A A A A T A T A A T A A T A A A A A A A T A T A T T T A A A A A T A A A A A A A A A T A A T A A T A A A A A T A A T T A A T A A A A T A T T T A A T A A T A A A A A A T T A A T A A T T A T A A A A T A A A A T A A A T A A A T A A A A A T A T T A A T A A A T A A T A A A A A A A A A A A A A T A A A A T T A T A A A T A A A A A A T A A A T A A A A A T A A A A A A +A A T T T A T T T T T T A T A A T T T A A A A A A A T A A A A T T T A A A A T A T A T A A A T T T A T T T A T A A T T T T T A A A A T T A A A A T T A A A T A A A A A T A T T A T T A A A T T T A A T T A T A T T A T T A T A T T A A A A A A A T A T A T T T A A A A A T A A A A T T A T T T A T T A A T T A A A T T A A T T A A T A A A T T A T T T A T T T A T A T A T A A T T A A A A A T A A T A A A A T T A T A T T A A T T A A T T A A T T T T T T T T T A A A T A A T A A A A A T A T A T A T T T A T A A T T A T A T A T T T A A A T T A A A T A T A A T T A A A A A T +G G C G G G C C C G G C G C G G G C C G G G G G G G G G G G G C C C G G G G G G C G G G G G C G C G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G C G G G G C C G G G C C G C G G G G G C G G G G G G G C G G G C C C G G G G G C G G G G G G G G G C G C C G G G G G G G G G G G C G G G G G G G G C G C G C G G C C G C G G G G G G C C G G G G G C G G C G G G G C G G G G C C G G C G G G C G G G G G C C C C G G C G G G C G G C G G G G G G G G G G G G G C G G G G C C G C G C G C G G G G G G C G G G C G G G G G C G G G G G G +G C C G G G C C G G G C G C G G G C C G C C G G G G G G C G G C C G G C C G C C C G G G C C C G C C C G C C G G C G C G G G G G G G G G G G G G C G C C G G G C G C G G C G C G C G G G C C G G G G G C C G G C C G G G G G C C C G C G G C G G C G G G C C C C G G G G C G C C G C C G C C C G C C G C G G G G C C G G G C G G C G G G G C C G C G C G C C C G C G C C G C G C C C C G G C C G C C G C C C C C C G C C C G C C G C C C C G C G C C C C C G G C G C G C C G C C C C C C C G C C G C G C C C C C C C C C C C C G C C C C G C C C C G G C C G C G C C G G G G G G +T A T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T A A T A A T T T T A A T T T A T T A T T T T T A T T T T T T T T T T T T T T T A A T T T A T A T T A T T T T T T T A T T T T A T T A T T T T T T T T T A T T T A T T A T T T T T T T T T A T T T T T T T A T T A T A A T T T T T A T T T T A A T T T T T T A T T T T A T T T T T T A T T T T T A A T A T T T A T T T A T T T T T T A A T A T T A T T T T T T A A T A T A T A T T T T T T T T A T T A T T A A A A A T T T T T A T T T A T A T T T T T T T T T T T A T T T T T T T T A T A T T T T T T T T T +T T T T T T T T T T T T A T T T T T T A T A T T T T T T A T T T T T A A T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T A T T T T A T T T T T T A T T T T T T T T T A T T A T T T T T T A A A T T T T T T T T A T T T T T A T T T T T T T T A T T A T T A T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T A T T A T A A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T A T T T T T T T T A T T T T T T T T T T T T T A T T T T T A T T T A T +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G C C G G G G G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +G C G C C C C G G G G G C G C C C G G C C G G G C G C C C G C C C C C G C G G C C G G G G C G G G C G C G G G G G G G G C G C G C C G G C G G C G G C G G G G C G C G C C G G C G G C G C C G G C C C G C G G G C C C C C G C G C C C G G C G G G G G C G G G C G G G G C G G C C C G G G C G G C G C C C G C G G G C G C G G C C G G G G G G G G G G C G G C C G C G C G C C G C C G C G G G C G G C G C C C G G G C G G C G C C C C C G G C C G C C G C C C C G C C C C G C C C C C C G C G G G C G G C G G C G G C G C G G C C G G C C G G G G G C C C G C G G G C C G G C C +A A T A T A A A T A A T A A A A A A A A A A A A A A A A A A A T A A A A A T A A A T A A A A T A A A A A A T A A T A A T A A A T A A A A A T T A A A A A A A A A T A A A A T A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T T A T T A T A A A A A A T A T T A T A A A A A T A A A T A T A A A A A T A A A T T T A A A T A T T A T A T A A A A T A A T A A A T A A A T A T A A A T A T T A T A A A A T A A T A A T A A A A A A A A A A A A T A A A A A A A A A T A A A A A A A A A T A A A A A A A A T T A T A T A A A A A A A T A T T T A A A A A A A A A A A A A A +T T T T T A T T T T T T T T A T T T T T T T T T T T A T A T T T T A T A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T A T T T T T A T T T T T T A T T A T T T T T T A T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T A A T T T T T T T T A T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T +G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G C G C G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G C G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G +G G G G G G C G G G G G G G G C G G G G G G G C G G G C G G C G G G G G G G G G C G G C G G G G G G G G G G G G C G G C G G C G C C G G G C G C C G G G C G G G G G G G G G G G G G C C G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G C G G G G G G G G C G G G C G G G G G C G G G G G C G G G G G G C G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G G G G G C G G G C G G G G G C G G +T T T T T T T T T T T T T T A T T T A T T T T T T T T T A T T A T A T A T T A T T T T T T A T A A T T T A T T T A T A T T T T T T T T A A T T T T A A T T A T T T T T T A T A T T T T T A T T T T A T A A T A T T A A A T A T A T A T A T A T T A T T T T T T T T T T T T A T A A T T T T A T T T T A A T T T A T A T T T T T T A T T T T T T T T T T T A T A T T A A T T T T A T A T A T A T T T T A T T T T A T A A T T T T T T T A T A A A A A T T T A A A T T T T A A T T T T A A T A T A T T A A A T T A A T T T T A T T T A A A A T T A T T T T T T T A T A T A T T T T T +A A A A A A T A A A A A A A A T A A A A A A A T A A A T A A T A A A A A A A A A T A A T A A A A A A A A A A A A A A A T A A T A T T A T A T A T T A A A T A A A A A T A A A A A A A T T A A A A A A A A A A A A A A A A T A A T A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A A A A A T A A A A A A A A T A A A T A T T A A T A A A A A T A A A A A A T A A T T A T A T A A T A T T A T T A A T A A A A A A T T A A A T A A A A T A A A T A A A A A T A A +C C G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G C G G G C G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G C C C C G G G G G G G G G G G G C G G G G C G G G G C G G C G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G +C G G G G G C G G G G G G G G C G C G C G G G C G G C C G G C G G G G G G G G G C G G C G G G G G G C G G G G G G G G C G G C G C C G C G C G C C G G G C G G G G G C G G G G G G G C G G G G G G G G G G G G G C G G G C G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G C G G G G G G G G C G G G C G C C G G C G G G G G C G G G G G G C G G C C G C G C G G C G C C G C C G G C G G G G G G C C G G G C G G G G C G G G C G G G G G C G G +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A +T T A A T A A T T T T A T A T A A A A A A T T A T T A A A T A T A A T A T A A T A A A A A A A A A A A T T A T T A A A A T A A T A A T A T T T T T T T T A T T T T A A A A A A A A T A T A T A A T A A A A T A T T A A A A T A A T T A A A T A A A A A T A A A T A T A A T A A A T A A T A T A T A A A A A A T T T A A T T T A A A A A T A T A T A T T T A T A A A A A T T T A A T T A A A A A A T A A T A A A A A A A A A A A A A A A A A A A T A A T A T T T A T A A T T A A A A A A T A A A A A A A A A T A A A A A A T A A A T A A A A A A A A T A A T A A A T A A A T A T A +C C C G C G C C G G G G G G C C G G G C G G C C C G G C C C C C G G C C G G G C C G G G C G G G C G G G G G G C C G G C G G C G C C G C C G G G G G C G C G C C G G G C C G C G G C G G C G G G G G G G G G G G G G G G G G C C C G C G G C G G G G G C G G G C G G G G C G G C C G G G G C C G G G G C C G G G G G G G G G G C C G G G G G G C C G G C G C G G G G C G G G C G G C G G C C G G G G G G C G C G G C C G G G G C C C C C G C C G G C G G C G G C C C G C G C C C C C C G C C C G G C C C C G C C G G C G C G G C C C C C G G C G G G G C G G G C C G G G G C G C +G C G G C C C G C C C C C G C C C G C C G C C C C C G C C G C C G G G C C C G C C C C C C C C G G G C C C G C C C G C C C G C C C C C G G C C G C G G C C C C C C G G C G C G C C C G C G G C C C C C G C C C C C G G G C C C G C C C G C G C C C C C C C C C C C C C C C C C C G C C C G G C C C C C G C C C C C C C C C C C C G C C C C C G C C C C C G C G C G C C C C C C C C C C C C C C C G G G C C C C C G G G C G C G C C C G C C G G C C C C C C C C C C C G C C C C C C G G C G G G G C G G G C C G G C G C G C G C G C G G C G G G C G C G G C G C C G C C C C C G C +A T A A A A A A A T T T T A T T A A A A A A T A T T A T T A A T A A A T A A A T A A A T T A A A A A A T T A T A T A T T A A T T T T T A A T T A A A A A A A T T T A A T A T A T A T A A A A T T T A T A T T A T A A A A A T T A T T A A A A A A A A A T A A A T A T A A T T A A A A A T A A T A A A T A A A A T T A A A A A A A A A A A A T A T A T A A A T A T A T T T T A T A A A T T A T A A A A A T T T A A A A A A A A A A T T A A T A A A T A A A T A A A T T A T T T A T T A A T A A A A T A A A A T A A A A A A T A A A T A A T A A A A A A A A A A A T A A T A T A A T +T T A T A A T A A T T A A T A T T A A T T A T T T T T T A A T A A T A A A A T A T T T A A A A A A A A T A T T A A T T A A T T T T T A A T A T T T A A A T A T A T T A A T A A A T A A T A T A A T A T T A A T T A T T T A A A A A T A A A A A A T A A A T T T A A A A A A T A A A T T A T T A T A A T A T A A A T T T A A A T A T A A T A A T A T T A T A A A T T T A A T A A T A A A T T A A T T T T A A A T T A A A A A T A T A A A T A A A A A T A A A A A T A A A A T A T A A A A A A T A T A A A A T T A A A T T A A A T T A A A A A A A T A A A T T A T A A A A A A T T A +G G C G G G C C C C G C C G G G G G G G G G G C G G G G G C G C C G C G C C G C C G G G G C C G C C G G C G G C C G G C C G C G G G C G G G G G G C C G C C G C G C G G G C C C C C G G G G C C G G G G C C G G C G G G C G G G C G C C C C C C G C C G G G G G C C C C G G C G G G G G G G C G C G G G G G G G G G G G G C G C G C C G C G G G C G C G C G C G G G G G G C C G C G C G C G C G C G G C G G C G G C C C G G C G G G C C C C G G C C G C G G G C C G G G G G C G G G G G G C G C C G C G C G G G C G G C G G G C G G G C G G G G G G G G G C G C G G C G C C G C +C G G G C C G C G G G C G G G G G G C C G G G G G G C G C C C C G C C C G G C C G G G G C G G C C C C G C C C C C C G C C G G G G G C G G G G G G G C G G G G C G G C C G C C C G C C G G G C C G C G G C G G G C G G G G G C G G G G C G C G G C G G C G G G G G C G G C G G C C C G C C G C C G G C G G C G G G G G C C C G C G C G G C G C C G G G G C G C C G C C G G G G G C G C C G C G G G C G G C C G G C C C G C G G C C C C G C G G C C G G G G C C G C C C G G C G C C G G C G G G G C G C G G G G G C G C G G C G G G G G C C C G G C G C G C G G C C C C C C G G G +T A T A A A A T T A A T T T A A A A T A T T T A T A T T T T T T A T T T T T A T A A A T T T T T T T T T T A T T T A A T T T A A A A T T A A A A A T T T A T T T A T T T T T T T A T T A T A T T A T A A T T T A T T T T T A T T T A A T T T T T T T T T T T T T T T T T T T A T A A T T A A T T T T T T A A T T A T A A A T A T T T T A T T A T T A T A T T T T T T T T A T A T T T T T A T T T T A T T T T A T T T T T T T A T T T T A T T T T T A T T A T T A T T T A A T A T T T T T T A T T T T T T A A T T T A T A A T A T A T T T T T T A T T T A T A A T T T T A T A A T +T A T T T T T T T T A T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A A A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A A T T T T T T T T T T T A T T T T T T A T T T T T T T T T A T T T A T T T T T A T T T T T T A T T T T T T A T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T A T A T T T T T T T T A T T T T T T T T T T T T T T +G C C C G G C G G C C C G C C C C C G G C G G C G G C C C G C G G G G C G G G C C C C G C C C G C G C C G G C C G G G G C C C C C C C G C C C G C G C G C G G G C G C C G G G G G G C C C C G G G C G G G G G C G G G G G C C G G G C G G G G G G G G C G G G G G C G G C G C G C G G C G C C C C C C G G G G C C G G G G G C C G C G C C G G C G G G C G G C C C C C G C C C G C C G C C C G C C G C G C C C C C G C G C C C G C C C C G G G G G C C G C G G C G C C C G C C C C G G C G C G C G G C G C G G G G G G C C G C C C G G C G G G C G C G C C C C G G C G G C C C G +G C G C G G G G G G C G G G C C G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C C G C G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G C G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G C G G G G G G G G G G C G C G C G G G G G G G G C G G G G C G G G G G G G G G +A A T A T A T T T A A T A T T A T A T A A A T T T A T T T T T T A T T T T T T T T T T A T T A A T A A A A T A T T T T A T A T A A A T T A T A T T A T A T T T T A A T T A T T T T T A A A T T T A T A A T A A A T A T A A T T A T T T A T T T T T T T T T T A T T T T T T A T T T T A T T T T T T A A T T T A A A T A T A T A T A T A T A A T T T A T A A T T A T A T A T A T A T A A A T T T A T T T A T T A T T T T T T A T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T A T A T T T T A T T A T T T T T T T A T T A A T T T A T T A A T T T T T T T T A T T T A +T A T A A T A A T A A A A A A A T A A A A T A A A T A T A A T A A A A A A A A A T A A T A T A T A T A A A A T A A A A T A A T A A A A A A A A A A A A A A A A A T T A A A A A A A A T A A A A A A A A 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A A T T A T T T T T T A A A A T T T A T A T A T T A A A A T A T T T T T T T A T T T T T T A T T T T T A A A T T T T T T T T T T T T A T T A A T T T T A A A A T A T T T A T T T T T A A A T T T T A T A A T A T T A T A T T A A T T T T A T T T A A A T T T A T A T A T T A A T A T T T T T T T +T T T T T T T T T T T T T T T A T T T T T T T A T A A T T T A T T T T T T T T T T T T T T T T A T T T A T T T T A T T T T T T T T T T T A T A T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T +C C C C C C C C C C C C G C C G C C C C C C C C C G C C G C G C C C C G C C G C G C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C 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T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +T T A T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G G G C C C G G C C G C C G G C G G C C G G C C C G C G C C C C C C G G G C C C G C C C C C C C C C C C C G G C C G G C C C C G G G C C C C G C C C G G C G C C C G C G G G G C G G G C C G G G C G C C C C C C C C C C G C C C G G G G C G C C C C G C C C C C C C C C C G C C G C C G C G G G C G C C C G C C C C G C C C C C G C C C C C G G G C C G G C C C C C C C G C C C G G C G G G G C G C C G C C C C C C C G C C G C C C C C C C C C C C G G G C C C C C C G C C C C C C C C C G C G G C C C C C C C C C C C G C G C G C C C C C C G C C C C C G G C C G C C G C C G +C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C G C C G C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C G C G C C C C C C C C G C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T T A T T T T T +A A A T T T A T T T T T A T T T T T A T T A A T T T T T T T T T A T T T T T A T T A A T A T T T T T A T A A T A A T T T A T T T T T T T T T T T T T A A A A A T T T A T T T T A A T T T T T A A T A A T A T T T T A T A A A T T A T A T T T T T T T T T T T A T T T T T T A A A T A A T T T T T A A T T T T T T T T T T T A T T T T T T A A T T T T T T T A T A T A A A T A A T T T T T A T A T T A T A T T T T T A T A T T T A T T T T T T A T T T A A T A A T A T T T T T T T T T T T T T T A A T T T T T T T T A A T T A T T T T A T T A T A T A T T A T T A A T T T T T A T +G C G C G C G G C C G C G C G C G C G G G G G C G C C G G G G C C G G G G G C G G G C C C C G G C G G G C C G G C C G C G C C G G G C C C C C G C C C G C C G G G G G G C G C G C C G C C G C C C G C C C G G G C G C C G C C G C G G G C G G G G C G G C C C C C C C G C G C G G G G G G G G G C G C C G G G C C G G C G C G C G C C G G G G G G C C G G G G G C G C G G C G C G G C C C G G C G G G G C C G C C G C G G G G G C C C G C G G C C G G C G C C C G C G G G C C C C C C C G G G G G C C G G C G C G G G C G G G G G G C G G G G G C G G G G C G C G G G G C C C G +C G C G G G C C C C C C C C G C C C C C C C G C G C C G C G C C C G C G G C G G C C C C C C C C G C C C C C C G C G G C C C C C C C C C C C C C C C G C G G C C G C C G C C G C C C C G C C C C G C C C C G G C C C C G C G C C G G C C C C G G C C C C C C C C C G C C C C G C C C C C G G C C G G C C G C C G C G C G C C G C C G C G C C C G G C C G G C C G C G C C G C C G G G C G G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C G C G C C C C C G G C G C G C C C C C G C C +A A A A T A T T T T A A T A A T A T A T T T T T A T T A T T T T T T A A A T T T T T T A A T T T A T T T T T T A T A A T T A T A A A T A T A T A A A A T T T T T A T T A T A A A A T T A T A A A A A A T T T T T A A A A A A T T A A T T T A A A T T T T T T T T T A T A T T A A A T T A T T T A T T T T T A T A T A A A T T A T T A A A T T A A A T T T A T T A A A A T T T T A T A T A A T T T A T T T T T T T T T T T T A A T T T T T T T T T T T T T A T T T T T A A T T T T T T T T T T T T T T T T A T T T T T T A A T T T A T T T A T T T A T A A T A A T T A T A T A T T +T A A T A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A T A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A T A T A A A T A A A A A A A T T A T A A A T A A A A A A A A A A A A A A A A A A A A A A T T A A A A A A A T A A A A A A T A A A A A A T A A T A A A A T A A A A A A A A A A A A A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A A T A A A A A A A A +G C G G C G G C G G G C G C C C G G G C G G G G G G C C G C C G C C G C G C G C C G C G G G C C C G G C C C C G G G C G G G G G G G G C C G C G G G G G G G G G G G G C C G G G G G C G G G G G G G C C C C C G C G G G G G G G G C G G C G C C G C G G C C C C C G C C G G C G G C G G C G C G G G C G C G C G G G G G C C G C C G G G C G C G C C G C C G G G C G G G G C G C C G C G G G G C G G C G G G C G G G G G C C G G C G G G G C C C C G G G G C G C G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G C C G G C G +C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C G C G G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C G C C C C G C C C C C C C C C C G C C C C C C C C C G C C G C C C C C C C C C C C G C C C G C G C G C G G C C C C C C C C C C C C C C C C C C C G C C C G C C C G C C C C C C G C G C C C C C G C G C C +T T A T T A A T A T T T A T T A T T T T T A A T T T T T A T T T T T T A T T A T A A T T T A T T T T T T T T T A A T T T A A T T T T A T T T T T T T T T A A T T T A A A T T A A A T T T T T A A T A T T T T T A T T T T T T T T T T A A T T T T T T T T T T T T T A T T T A T T T T A T T A T T T T T A T T A A T A T A T T T T T T T T T A T A T T T T T A T A T A A A T T A T T T T T T T A T T A A A T T T T T A T A T T T A T T T T A T A T T T A A A T A T T T T T A T T T T A T A T T T A A A T T A T T A T A A A T A T T T T T T T A T A A A T T T T T T A T T A A T T T +T A T A A A T A T A A A T A A T T A T A A A T T T T A A A A A A A A T T A A A A A A A A T A A A A A A A A A A A T T A A T A T A A A A A A A A A A A A A T T T A A A A A A A A T T A A A A A T T A A A A A A A A T T T T A T T A A A T A A T A A A A A A A A A A A A A A A T A T A A A A A T A A A A A T A A A T A T A A A A A A A A A A A A A A A A T A A A A T A T T A T A T A A T A A T A T A A T A T T T A A A A A T A T A A A T T A A A A A A A A T A A A A A T A A A T A T T A A T A A A T A A A A T A A A A A A A A A A A A A A A T A A T T A A T A T A A A A A T A T A A +C G G G G G C G G G G G G C G G C G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G C G C G G G G G G G G G C G G G G G C C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G +C C G G G G G C C C G C G C C C C C C C G G G G C G G C C C G C G C C C C C C C C G C C C G C C C C C C C C C G G C C C C G C G G G G C C G C G G G C G C G G C G G C C G G G G C G G G G C G G G C C G C C C G C G G C C C C C C C C G C C C C C C C C C C C C C G C C G G C C C C G C C C C C C G G G G G C C C C G G C G C C C G G C C G C G C C C C C G G C G G G G C C G C G C C C C G G C G G G C C G C C G G C C C C G G G C C C C C G G C C C G G G G C C C C G G C C C C G G G C C C G C G G C C C C G G G G G G G C C G C C C C G C G C G G C C C G C C C C G G G C C +T T T T T T A T T T T A A T A T T T T T T T T T A T T A A T T A T A T A T T T T A T T T T T A T A T T T T T T T T T A A T T T T T T T A T T T T T T A T T T T A T T A A T A T T T T T T T T T T T A T T T T A T T T T T T T T A A A T A T T T T T T T T T T T T T T T T T T A T A T A T A T T T A T T T T T T T A A T T A T T T A T T T T A T T A A T A T A T T T T T A T T T A T T A A A T A T T T T T T T A A T A A T A A A A T T T A T T T T T A A T T A T A A T A A T T A T T T T T A T A T T T T A A A A T T A A T A A T A A A T A T A A T T A T T T T T T A T A T T A T A +T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T +C G G C G C G G G G G G C C G G G C G G G G G C G C C C C G G C G C G G G G G C G G C G G C C C C G C C C G C G C G C G G C G G G G C G C G C C G C G G C G C G G C G C G G G G G G C G G G G G G G C G C G C G G G G G G G C C G C G G C G G G C C G G C C G C C C C G C G G G G C C G C G C G C G C C G G G G G G G C C G G C G C C G G C C C C C G C C C G G G G C C G C G G G G C G G G G G G G G G C C C G G C C G C G G C G C C G C G G G C G G G G G G G G C C G G C G C C C C C C G C G G C G C G G C C G C C C G C G C G C G C G C C G G C C G C G G G G G G C C G C C +G G G G G G C G G G C G G G G C G G G G G G C G C G C C C G G C C C C G G G C C G G G G G G C G C G G G G G C G G G C G G G G C C C G G G C C G G G G G C C G G G G C C G C C G G G G G G C G G G C G C C G C G G G G G G G G C G C G C G C G G C G G G G G G G G G G G G G G G G G G G G C C G G C G G G C G G G G C G G G G G G G G G G G G G C C C C G G G G G G G G C C G G G C C G G C C C G G G G G G C G G G C G C G C G G G G G G C G G C G C G G C G G G G C C G G G G G G G G C G C G G G G C G G C G G G G G C G G C C C C C G G C G G G G G G G C C C G G G G C G C +T A A T A T T A A A A A T T A T A A A A A T T T A T T T T A A T A T T A A T A T T T T A A A T A T T T A T T T A T A T A A T A A A A T A T T T T A T A T T T T A A T T T A T T A A A T A T T A A A T T A T A T T A T A T A A A T A T A T T T A A T T T A T T A T T T T A T A A A A T T A T T T A T A T T A A A A A A A T T T A A A T T A T T T T T T A T T T A A A A A T A T T A A T T A A A T T A A A A A T T A T T T T T A T T A T T A T T A T T A T A A T A A A A T T A T A A A T T T T T T A A T T T A A T T T T T A T T T T T T A T A T T A A T T A T A A A T A A T A T T T +T T T T T T A T T T A T T T T A T T T T T T A T T T T T T T T T A T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T A A A T T T A T T T T T T T A T T T T T T T A A T T T T T T A T T T T T A T T T T T A A A T A T T T T T A T A T T T T T T T T T T T T T T T T T A T T T T T A T T T A T T T A T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T A T T T T A T T T A A T A T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T A T A T T T T T T A T A A A T T T T T A T T +G G C G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G C C C G C G G G C G G G C G G G G C G G G G G G G G G G G G G G C G G G G G C G G G G G G C C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G C G G C G G G G G G G G G G G C G G C G G C G G G G G G G C G G G G C C G G G G G G G G G G G G G G G G G G G G G C G C G G G C G G C G C G G C G G G C C G C G G G G G G G G G G C G C G G G G G C G G G G G C G C C G G C G G G G G G G C G C G C C G G G G G G G G G G G G G +C C C G C C C C G C C C C G C G C C G C C C C G G G G G G C C G C G G C C G C G G C G C C C C C G C C C G C G C G C G C C C C C C C C C G C G C C C C C G C G C C C C G G C C C C C C C C C C C C C C C G C C C C C C G C C C G C G C C G G C C G G G C G G G G G C G C G C C G C G C G G C G C C C G C C C C C C C C C C C G C G G C C C C G C G G C G G C C C C C C C C G C G C C G C C C C G C C C C C G C C C C G C C C C C C C C C C G C C G C G C C C C C C C G C C C C C C C G C G C G C C C C G C C G C C C C C C C C C C G C G G C G C C C C G G G C C C C G G C C G G +A A A A T A A A A A T A A A A A A A A T T A A A A A A T T T A A T T A A T A T A A A A A A A A A T A A T A A T A A A T A A A A T T T A A A T T T T A T A T A A A T A T T A T A A A A A A T A A A T T T T A T T A T A A A A A T T T A A A A A T T A A T A A A A A A A A T T A T A T A A T A A T T A T T A T T A T T A T A A A A A A A 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C G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G C G G G G G C G G G G C G G G G C G G G G C G G G C C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G +G G C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C G C C C C C C C C C C C C G C C C C C C C G C C C C C C G C C C C C C C C G C G G C G C C G C C C C C C C C C C C C C C G C C C C C C G C G C C C C C C C C C C G C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C G C G C C G C C C C C C C C C G C C C C C G C C C C G C C C C G C C C C G C C C G G C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C C C C +T T A T T T T T T A T A A T T T T T A A T T T T T T T T T T T T T T T T T T T T A A T A T T T T T T T T T T T T T T T A T A A A A A A T T T T T T A T T T T T T T T A T A T T A A T T T T A A A T A T T T T T T T T T A A A T T T T A T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T A A T T T T A T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T A T T T T T T T T T T T T T A T A T T T T A A T T T T T A T T T T T T T T T T T T A T T A T T T A T A T T T T T T T T T T +T T A A A A A A A A T A T T A A T T A A A A A A A T A A T A A T T A A A A A T A T A T A A T A A A A A T A T A T T A T A T T A A A A T T A T A T T A T A A A A A A A A A A A A A A A T T A A A A T A T T A T A A A T T A T A A A T A A T T T A A T T A T T T T T T A A A A T A A A T T A T A A T A T A A A T T T A T T A A A A A A A A A A A A A A T T T T A T T T A A A T A A A A T T A A T T A A A A T A A A A A A A A A A A A A A A A A T A T A T A A T A T A A A A A A A A A A T A T A A A A T T A A T A A T A A A A A A A A A A T A A A A A T A A A T A T T T T A A T A T A +C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C C G C C C C C C G C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C +G G G G C G G C C G C G C C G C C C G G C C C G G C C G C C C C C C C G G C C C C G C G C C C C C G C C G C C C C G C G C C G G G G C C G G G C G G C C C G C C C G G C G G G G G G C G C G G G C G C C G C G G C C C G C G G C C G G C C C G G C C C C C C C C C C C G C C G G G C G G C C G C C C C G G C C C C C C C C C C C G C G G G C G G G C C C C C C C C G C C C C G G C C C C C C C C G G G C G G G G C C C G G G G C G C G C G C C C C C C G C G C C C G G G G G G G G C G C C C C G G C C C C C C C C C C C G C C G G C C C G C C G C C G G C G C C C C C G C C C C +A A T T T T T T T T T T T T T A A A T T T T T A A T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T A T T T T T T T A A A T T T T T T A T T T A A T T T T T T T T A T T T T A A T T T T T T T A A T A T T T T T T T T A T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T A T T T T T T T A T T A T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T A T T T +A A T T A T T A A A A T A A A A A A A A A A A T A A A T A A A A T A A T T A T A A T A A T A A A A A A T T A A A A T A T A A A T T T A A A A A A T A A A A T A A A A A A T T T T A T T A T T A A T A T T T A A T A A A T A T A A A A T T A T T T A A A A A A A A A A A T A T A T A A A A A A A A A T A T T T A T A T T A A A A T T A A A A A A T A A A A A A A A A A A A A A T A A A A A A A A T A T A A A T A T A A T A A T T A A A A A A A A T A A T T T T T A A A A T A A A A A A T A A A A A A A A A T A A A A A T A T A A T T A T A T A A T T A A T A T T T A A A A T A A A +C C G G G G G G G C G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G C G G G G G G C G G G G G G G G G G C C G G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G C G G G G G G G G G G G G G G G G G G G G G G C C G G G G G C G G G G G C G G G C G G G G C C G G G C G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G C G C G G G G G G G G G G +C C G G G C G G C G C G G C C G G C G C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G G C C C G C G C G C G G C G G G G C C G G G C C C C C C C C C C C G C C G G G G C G C G G C C G G C C G C C C C G G C G C C G C G G G C G C C C G C C G G C G G G G C C G C C C G C C G C G C C C G G C G C C C C C C G C C C C C C C C C C C C C C C C C C G G C C C C C C G C C C G C C C C C C C C C C C C C C C C C C G C C G C C C C C G C C C C C G C C C C C G C C C C C C C C C G G C C C C G C C G C G C C C G C C C G G C G C C G C C C C C G C C C C G C C G G C G +T T T A T T A T T A T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T A T T T T A T T T T T T A A T T A T T T T T T T T T T T A A A A T T A T T T T T T T T T T T T T T T A T A T T T A T T T T T T T T T T T T T T T A T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T T A T T T A T T T T T T T T T T A T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T A T T T A T T T A T T T T T T A T A T T T A T T T A T T +A T T A T T A A A A A T A A T A T A A A A A A A A A A T A A A A T A A A A A T A A A A A A A T A T T A A T T T T A A A T T T A T T T T A T A A T A A T A A A A A A A T A T A A A A T A A T A T T T T A T T A A A A A A A A A T T A A T T A T A A A T A A T T A T T A T A A T T A T T T A T A A A A T T T T T A A A A T T T T A A A A A A A A T A A A T A T A T T T A A A T A A A A T A T A A A A T A T A T A A A A A A A A A A A T T A A A A A T A A A T A A A A A T T A T A A T T T A T A T T T A T A T A A T T T A A A A A A A A T T T A A T T A A A A T A T T A A A A A A A T +G C C G C C G C G G G C G G C C G G G G G G G G G G G C G G G G C G G C C G C G G C G G G G C G C C G G C C G C G G G C C C G C C C C G C G G C C G G G G G G G G G C G C G G G G C C G C C C C C C G C C G C C G C C G G G C C G G C C C C C C G C G G C C G C C G C C G C G G G C C G C G G G G C C C C C G G G C C C C C G G C G G G C G C C G G G G C G C C C C G G G G C G G G G C C G C C C C C G C C G C G G C G G C G G C C G G C G G C G G C C G G G G G C C G C C G C C C C C G C C C G C G C C G C C C G G G G G G C G C C C G G C C G G G G C G C C G G G G G G C C +G G G C G G C G G C G G C G G G G C C G G G G G C G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G C G G G G C G G G G G G C C G G C C G G G G G G C G G G C C G C G G C G G G G G G G G G G G G G G G C G C G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G C G G G G G G G G G G C C G G G G G G C G G G G G G G G G C G G C G C C G G G G G G G G G G G G G G G G C G G C G G G C G G G G G G G G G G C G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G C G G G C G G G C G G G C G C C G C G G G C G G G G G G +A T A T T A T T T T T T T T A T T T T T T T T T T T T A T T A T T T T A A T T T T A T T T T T T T A T T A T T T T T T T A A T T T T A T T T T A A T T T T T T T T T T T T T T T T A T T T A T T T T T T A T A T T T T T T T T T T T T T T T A A T T T T T T T T T T T A T T T T T T A T T T T A A T T A A T T T T T T T T T T T A T T T T A T A T T T T A A A A T A T A T T A T T T A T T T T T T T T T T T T T T A T T T T T A T T T T A T T T T T T A T T T T T T T T T A T T T A T A T T T T T A T T T T T A T A A T T A T T T T T T T A T A T A T T T T T T T T T T T T T T +A T A T T A T T T T T T T T A T T T T T T T T T T T T A T T A T T T T A A T T T T A T T T T T T T A T T A T T T T T T T A A T T T T A T T T T A A T T T T T T T T T T T T T T T T A T T T A T T T T T T A T A T T T T T T T T T T T T T T T A A T T T T T T T T T T T A T T T T T T A T T T T A A T T A A T T T T T T T T T T T A T T T T A T A T T T T A A A A T A T A T T A T T T A T T T A T T T T T T T T T T A T T T T T A T T T T A T T T T T T A T T T T T T T T T A T T T A T A T T T T T A T T T T T A T A A T T A T T T T T T T A T A T A T T T T T T T T T T T T T T +C G C C C C C C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C C G C C C C C C G C C C C C G C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G G C C C C G C C C C C C C C C C G C C C C C C C C G G C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C G C C C C C G C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C G G C G C G C C C C G G C C +C G C C G C C C C C G C C C C G G C C G G C G G C G G C G G C G C G G C C G G G C C G C C C G C C C C G C C G C G C G C C C C C C C C G G C C C C C C G G G G G C G G G C C C G C C C C C C C C C C G C C C C C G C C C G C C G G C C C C C C C C C C G C C G C C G C C G G G C G C C G C G C C C G G C C C C C G C C G G C G C C G G C C C C C G G C G C C C C C C C C C G C C G C C G C G C C C C C C C C G C G C C C G C C C C G C G C C G G G C C C G C G G G C G C C C G C C C C C G G G C C C G G C G G C G C C G C C G C C G G G C C G C C C G C C C C G C C G G G G C G +T A T T T T A T T A T T T T T T A T A T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T A T T A A A A T T T T T T T T T A T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T A T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T A T T T T T T T T T T T T A T T T T A A T T +T A T A T T A A A T A T T T T T A A T T A T A A A A T A A A A T T T A A A T T T A A A A T A T A T A T A A T T A T A A T A T T A T T A A T A A T A A A A A A A T T A A T A A A A A T A A A T A A A A A T A T A T T A A A A A A T A T A A A A A A T A A T T T T A A A A A T A T A A T A A T T T A A A A A A T T A T T T A T T T A A A A T T A T A A T T T T A A A A T T A T A A A T T A A A A T T A T A A A A A T A A T A A T A A A A A A T T A T A T T T T T T A A T T A A A A A A A A A A T T A A A A T T A T A T A A A T A A T T T T T A A T A T A A A A A T A A A A T A A A A +G C G G C G C G G C G G G G G G C G C C C G C C G C C G G C C C G C C G G G C G G G C G G G C G G G G C G G C C C C G G G G C G G G G G G G G G G G G C G C G C G G G C G C C C C G G G C G G G C G G C G G G G C G C G C C G C G C G G G G G G G G G G G G G G G C G G C C C G C G G C G C C G C C C G G G G G C G G C C G C G G G G G C C G G G C G C G C G G G C G C G C G G G G G C G G G G G G G G G G C G G C G G C G C C G C G C G G G C C G G G G C C G G G C C G G C G G G G G C C C G G G G C G C C G C C C G C C C G C C C C G C C G G C G G G G G C G G C G C C G C +C C G C C G C G G C C G G G G C C G C C G G G C G C C G C C G C G C C G G C C C G G C G G C C G G G G C G G C C C C C G G G C G G G G C C G G G G C G C C C G C G G C C G C C C C G C C C G G G C G G C G G G G C C C C C G G C G C G G C G G G G G G C G G G G G C G G C C C G G G G C C C C G G C C G G G G G C G G C C G C G G G G G C G G G G C C C G G G G G C G G C C G C C C G C C C G G G G G G G G G G C G G G G G C G G C G G G G C C G G G G C C C G C G C C G G G G G G G G C C C G C G C C G G C G C G G C C G C G C C C C C G C G G G G C G C G C G G G G C C C C +T A T A T T A T T A T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T A T T T T T A T T T T A T T T T T A T T T T T A T T T T T T T T T T A A T A T T A T T T T A T T T T T T T T T T A T A T T T A T T A T T T T T T T T T T T T T T T T T A T T T T A T T A T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T A T T T T T A A T A T T T A T T T T T T T T T T T T A T T T T T T T T T T T A T T T A T T T A T T T T T T A T A T T T T T T T T T T +T A T A T A A A A A T T A A A A A T A A A T A A A A T T A T T T T T T T T T T T T T A T A A T A T T A A T T A T T A T T T A A T T T T T A T T T T A A A A A A A T A A T T A A T A T T A A T A A A T T T T A T T A A A A T A T T A A T T A A T T A A T A A A A A A T A T A A A A A A A A T T A A T T A A T T T T A A A T T T T A T A A T T T T A A T A A A T T T A T A T A A T A A A A A T A A T T A T T A T A T A T T T A T A T T A T A T A A A A T T T A A A A A T T A T T A T T T A T T T T T A T A T T A T T A T T A A T T T A T T T A T T T T T A A A A T T A A A A T T A T +G C G C G C G G G G G G G G G G C G G G G G G G C G G G G C G G G G G G G G G G G G G G C G G C G G C C G G C G G G G G C C G G G G G C G G G G G G G G G G G G G C G G G G G G G G G C C G G G C G G G G G G G G C G G G G G G C G G G C C G G C C G G C C C G C G C G G G G G G C C G C G G C G G G C G G G G G G C G G G G C G G C G C G G C G G C G G G G G C C C G C G G C G C C G G C G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G C C G G G G G G C G G G G G C G G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G +C G C C C G G C C G C C G G C G G C G C C C C C C C G C G G G C C C C C C C C C C C C C G C C G C C G G C C G C C G C C G G G C C C C G G C C C C G C C C C C C C C G C G G G C G C C G G C G G G C C G C C C C C C C C C C C C C G C C G G C C G C C G G G G C G C G C G C C C C G G G G C G G G C C C C C C C C C G C C C C G C G C C C G C G C C G C C G C C G G G G G C C C C G G C C C C C C C C C C C C C C G C C C C G G C C C C C G G C C C C C G G C G C C C G C C C C C G G C C C C C G G C C C C C G C G G C G G C C G C C C C G C C C G C C C G C C G G C C C C C C +A T T T T A T A T T T T T T T T T T T T T T T T A T T T T A T T T A T T T T T T T T T T T T T T T A T T A T A T T T T T T T T T T T T T T A A T T A T T T T T T T A A T T T T T T T T T A A T T A T T A T T T T T A A T A T T T T T T T T A T T A A T T A A A T A T A T A T A T T A A T A T T A T T T A T A T A T T A A T A T A T T A T A T T A T T T T T T A T A A T T T T T T T T A T T T T T T T T T T A T T A T T A T T T T T T A T T A T T T T T T T T T T T T T T T T T T T A A A T T T T T A A T T T T A T T T T T T T T T T T T T T T T A T A T T T A T T T T T T T T T +T T T A A T A T T A T T A A T A T T A A T T T T T A T A T T A T T T T T T A A A A T T A T T A T T T T T T A T T T A A T A T A T T T T T A T T A T T A T T T T T T T T T A A A A A A A T A A T T T A A T T T T T T T T T T T T A T A A A T T T T T T T A T T T T T T T T T A T T T T T A T A A T A A T T A T T T A T T T A T T T T A T A T A T T T A T A T A T A T T T A T T A A T T T A T A A T A T T A T T A T T A T T T T A A T T T A T T A T A T T A A A A A T T A A T T T A T T T T T A A A A T T A A T A T T A A T A A T T A A A A T A A A T A T T T T T A T A T T A A T A +G G C G G G G G G G G C C G C G C G G G G C G G G G G G C G G G C G C C C G G G G C G G C C G C C G C C G G C C C G C C G G G G G G C C G C C G C G G G C G C G C G G G G G G G G G G C G G C C C G C C C C C C G G G C G C G G C G G C G G C C G G G G G G G C G G G C G C G C G G G G C G G G G G C G G C C G G C G C G C C G C G G G G G C G C G G G G G G G G C C G G G C G G G G G G G G G G C C G G G G C G G G G G C G G G G G G C G G C G C C G G G G G C G C G G C G G G G G G G G G G G C G G G G G G C G G C G G G C G G G G C G G C G G G C C G C G G C G G G G G G +G C G G G G C C C C C G G G G C G C C C G G G G G G C G G C C C G C G G G G G G G G G G G G G G G C G G C G G G G C G G C G C C C C G G C G G G G C G G G G G G G G C G C C C C C G G G G C G G G G G G G G G G C C C G G G C G G C G G G G G G G G C G G G G G G C G G C G C G C C G C G G C G C G G C G G G C G G G G G G G G G C G G C C G C G C C C C C C G G G G C C G G G G C G G C C G C G G G G G C G G C C C C G G C C C C C G G C C G G G G C C C G C G C G C C G C G C C G C C G G G C G C G G C G C G C C G C C C G C G G G G C G G C C G G G C G G C G G C C C G G +T A T A A A A A A A A T T T T A T T A T T T T T T T T T T A A T T A T T T A A A A T T A A T T T T A T A A A T T T A A T A T A A A A T T A T T A A A T T T T T T T A A T A A A A A T A T A A T T A A T A A T T T A T T T A T A T T A A A T T T T T T A A T T A T T A T T T T T T T A A A T A A A A A T T A T T A T T T A A A A T A A A T T A A A A A A A A A A T T T A A A T A T T A A A T A A A T T T T T A T T A A A T T T A A A T T T T A A A T T A A A A T A T A T A A T A T A A T A A T T T A T A T T A T A A A A A A A T T A T A T T A T A A A A T T A T A A T T A A A T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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A T T T A A A T T T T T T T A T T T T T A T T T T T A T T T T T T T T T T T A T T A T T T T T A A A T A A T A A T T T T A T T A A T T A A T T A A A T A A T T +T A T A A A T A A A T T T A A T A T A T T A A T A A A T A A T T T T A A A A T A A T T T A A A A A T A T A A A A A T T A A A A T T T T A A T T T T T T A T T A T T T T T A T A A A A A A A A T T A A T T T T A T T A T A T T T T A A A A A A A A A A T A A A A T A T A A T A T A A T A T A A A T T T A T T T T A T T T A T A A A A A T T T T T T A A A A T T A T A T A T A T T T A A T T T A A T A A T A A T A A T T T T A A A T T T T T T T T A T T A T T A T T T T T A T T T T T T A A T T T A A A T T T T T T A T T T A T T A A T T T A T T A A T T A A A T T T T A A A A T T +C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T T A A A T A T T T A T T T T T T T T T T T T T A T T T A T T T T A T T T T T T A T T A T T T T A T T T T T T T T T T T T T A T T T T T T T T T T T A T T T A T T T T T A T A T A T T T T T T A T T A A A T +G G G G G G G G G C G G G C G G G G G G G G G G C G C G G G C C G G G G G C C G G G C C G G G G G G G G G G G G G G G C G G C G G G G G G G C G G C G G G C G G G G G G G G G G C G G C G C G G G G G G C G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G G G G G G G G G C G C G G G C C C C C G G G G G C G C G G C G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G C C G G C G G G G G G G G G G C G C G G C G G G G G G G G G G C G G C C C C +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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A T T T A T T T A T T T T T T T T T T T A T T T T T A T T T T T A T T T A T T T T A T T T T T T T T T T T T A T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T +G C C C C C G C C C G C C C G C C C C C C C C C C C G C C C G C G G G C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C G C C C C C C C C C C C C C G C C G G C C C C G G C C C C C G G G C C C C G C G C C C C C C C C C G C G C C G C C G G G C G G G C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C G C C C C C C G C G C C C C C C C C C G C C G C C G C C G C C C C C G C C C C C C C C C C C G G C C G G C G C C G C C C C C C C C C C C C C C C G C G G C C C C C C C C C C C C C C C C C C G C G C C G G C C C C C C G C C G C C +C C C G C G C C C G C C G C C G G C C G G C G C C C C C C G C C C G G C C G C G C G C C G G C C C G C C C C C G C G C G C C C C G C C G C G C G C G C C G G G C G C G G G G C C G C G C C G C C G G G C C C C C C G C C C G C C G G C G C C C C G G C C G G G G G 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T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T A T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T A T A T T T T T T T T T T T T T T T T T A T T T A T T T T T A T A T T T A T T T A T T A T T T T T T T T T T T T T T T T T A A T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A T T T T T T T T T T T T A A T T +C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C G C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C G C C C C C C C C C C C G C C C C C C G C C C C G C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G G C C C C C C C G C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C G G C C +G C G G G G G 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G G G C G C G G G G G G G G G G G G G G C G C G C G G G G G G G G G G C G C G G G G G G G G G G G C G G C C C G G C G G G G G G G G G G G G G C G G G C C G G C G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G C G G G +G C C C C C C C C C C C C C C C C G G C C C C C C C C C G C C C C C C C C C C C C C C G C C C G C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C +A T T T A A A T T A T T A T A A A T T A A A A T T T A T T T A A T T T A A T T T A A T A A T T A T A A A T T T T T T T A T A T T T T T T A A T A T T T T T A T T A A T T A T T T T T T T A A T T T A A T T T T T T A A T T A A T A A T T A T A T T T A A T T T T T A A T A T A T A T T T T T T A T A A A A A T T T T A A A T A A A T T T A A T T A T A T T A T T A T A A A T A A A T T T T A T A T A T A T A T T A T T A T T T A T A T T A A A A T A A A A T T A A T T T A T A T A A T A T A T A A T T T T T T A A A T T T A T T T T T T A A T T T T A A T T T T A T T A A T T T +A T T A T T A T T T A A T T T T T A A T T T T T T A T T A T T T A A A T T A A T T T T T T T T T A T T T T T A T T T T T A T A A A A T A T T T T A T T T A T T T T T A A T T A T A T T A T T T T T A A A T T T T T T T T A A A T T T T A T T T T A T A T T T T T T T T T T T A T A T T T A A A T T A T T T T T T T T T T T A A T T A A T T T T T T A T A T T T A T A T T T T T T T A A T A T A T T A T A T A T T T A A A T T A T T A T A T T A T T T T A T A T T A T T T A T A T A T T T T A T A T A A T T A T T A T A T A T T T T T T T T T T T T A T T A A T T T T T T T T T T +G G G G G G G G G C G G C G C C C G G C C C C G G G C G G G C C G G G C C G G G G C G C C G G C G C C C G G G G G G G C G G G G G G G G C C G C G G G G G C G G C C G G C G G G G G G G C C G G G G G G G G G G G G G G G G G G C C G G C G C G G G G C G G G G G C C G G G G G G G G G G G G C G G G G G G G G G G G G C G G C C G G G C C G G C C C G G C G G C G C C G G C G C G G G G C G C G G G G G G G G C G G G G G G C G G G G C C G G G C G G G G G G G G G G G G G G G C G C G G G G C G G G G G G C G C G G G C G G G G G G C C G G G G C C G G G G C G G G G G G G +G G C C G G G G G G C G G G G G G G C G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G C G G G G G C G G G G G G G G C G G G G G G G G G G G G G C C C G G G G G G G G G G G G C C G G C C G G G G G G G G G G G C G G G G C G C G G G G G G G G G G G G G C G C C G C G G G G G G C G G G G G G G G C G G G G G G G G G G G G C G G C G G G G G G G C G G G G G G G G C G G G G G G G G G G G C G G G G G C G G C G C G G C C G G G C G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C C G G G +T A T T T T T A A T T A A A A T T A A T A T A T T A T A T A T A T A A T T A A A T A A T A A A T A A T T A A A A A A T A T T A A T A A T A A A A A T T A A A A T T T T A T A A A A A A T A A A A A A A T A A A A A A A A A A A A A T A A T A T A A A A T A A A T A A T A A A A A A A A A T A A A A A T A T T T A A A T T A A A T T T T A A T A A A T A T A T T T T A A A A T A T T T T A T T T T T T A T A A A A T T T T A A A T A A A T A T A T A A T T T A A T A A A A A A A A A T A T A T A T T A T A A A A T A T T A A T A A A A A A T A A A T T T A A A A A A A T T T A A A +T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T A T A T T T T T T T A T T T T T T T A T T T A T T A T A T T A T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T T A A T T T +C G G C C G C G G G C G C G G G G G G G G G C C C G G C C G G C C G G G G G G G C C C G C G G G G C G G G G G G G G G C C C G G C G G C G G G G G C C C G C G C G G C G G G G G G G G C G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G C G C C G G C G G C C G G G G G C C C G G G C G C G G G G C C G G C G G C C G C C C C G C G G C G C G G C G G C G C G G G G G G C C C G G C C C C G C G C C G G C C G G G C G G G G G G G C G G C G C G G G G G C G G G G G C G G G G C G G G C G C G G G G C C C C C G G G +G C C C C C C C C C C C G C G C C C C C C C G G G C C G C C C G G C C C C C C C C G G C G C C C C G C C C C C C G C C G C C C C C C C C G C C C C G G G C G C G C C C C C C C C C C C G C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C C C C G C C C G G C C C G G C C C C C G G C C C G C G C C C C C C C C G C C G C C C C G G C C C C C G C C C G C C G C C C C C C C C G C G C C C G G C C C C G C C C G G C C C G C C C C C C C C C C G C G C C C C C C C C C G C G C C C C G C C C C C G C C C C G G G C C C C C +T T A A T T A T T T A T T T T T T A T A T T T A A T T A A T A A A A A T T A A T T T T T T T T A T T A A T T T T A T A T A T T A A T T A T A T A A A A A A T T A T A A A A T A T A T T A A A T T T A A A T T T T T A A T A T A T T T T A A T A T A T A A T T T A T A T T T T T T A T T T A A T T T A T T A T A T A T A T T T A T A A A T T A T T T A T A A A A A A A A T T A T T T A A A A T A T A A T A T A A T T A A A T T T A T A A A T T A T A T T A T A A T A T A A A T A A A T T T T A T A T A A T A T T T A T A T T A T A A T T T T T T T A A A T T A T T T A A T T T T T +A T T A A A T A A A A A A A A A A A A A A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T A A A T A 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C G G G G G G G C C G G G G G G G C C C G G G C G G C G G G G G C G G C G C G G G G G C G G C C C C C C G G G G C G C G G G C C G C G C G C C C C G C C C C G C C C C C C G G C C C G C G C C C G C G C C C G G C C C G G C G C C C G G G G C G C G G C C G G C C G G C G C G C C C G C C G G C G C G C C C G C G G G G G G G G G G G G G G G G C G G G G C C C C G G C G G G G C C C G G G G G G G C G G G G G G C G G G C G G G C G G G G C G C G C C G C G C G G C G G C G C C G C C G C C C G G C C G G G G G G C C C C G G G C C C +A A A A A A A A A A A A A A A A A A A A A A A T T T A A A A A A T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A T T A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A T A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A T T A A A A A A A A A A T A A A T A A A A A A A T T A A A A T A A A A A T A A A T T A A A T A A A A A A A A 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G G G C G G G G G G G G G G G G G G C C G G G C G G G G G G C C C G G G G C G G G G G C G C G C C C G C C C G G G G G G G G G G G C G G G G G C G G G G G C G G G G G G G G C G G G G G G G G G G G G G G +C G G G C C C C C G G G G C C G G G G G G G G C C G G G C C G G G G G G G C G C G G G C G G C G G G G G G G G C C C G G C G G G G G G G C G G G G C G C G G C C G G C G G C G C G G C G G G C C G G G G C C C C C G G C G C G C G C C G G C G C C C G G C C C G G C G C C G G G G G G G G G G G C G G C C G G C G C G C G G G G C G C G G G G G C G G G G G C C G C G G G G G G G G C G G G G G C G C C C G G C G C G G C C C G G G G G G G G G G G G G G G G G G C G G G C G G G G C G C G C C G G G C G G C G G C G C C G C G G C C C G C C C G G G G G G G C C G C G C C C C +T T T A T T T T T A T A A T T A A T T A A A T T T T A A T T A A A A A A A T A T A T A T T A T A A T A A A A T T T T A T T A T A T T A A T A T A A T A T T T T T A A T A A T T T A T T T T T T T T A A A T T T T T A A T A T A T T T T A A T A T T T A A T T T A A T A T T A A A A A T A A A A A T A A T T T A T T T T T A T A A T A T T A A A T T A A A A A T T T T A T A A T A A A T T T A T A T A T T T A T T A T T A T T T T A A T T A A A A T A A A A T T A A T T T A T A T A A T A T A T T A A A T T A T A A T T T T T T A T T T T A T T T A T A A A A A T T A T A T T T T +T T T T A A T A A A T T T T A T T T A T A T T A A T T T T A T T T T T A A T T A T T T A T T A T T T T T A A T T T A T T T T T T T T T A A T A T T A T A A T A A T T T T T A T A A T A T T T T T A T T T T A A T A T T T T A T A T A T T A A A A T T T T T T T T T T A T T A T T T T A T T T T T A T T T A T T A T A T A T A T T A T A T T T A A A T T T A T T T T T T T T T T T T T A T A T T T T T A T A T T T T A T T A T A T T A T T T T T T T T T T T T T T T A T T T A T T T T A T A T A T T T T A T T A T T A T A A T T T T A A A T A A A T T T T T T A A A T A T T A A A +C C G C G G C G G C C C C C G C C C G C G C C G G C C C C G C C C C C C C C C G C C C G C C G C C C C C G C C G C G C C C C C C C C C G G C G C C G C G G C G G C C C C C G C G G C G C C C C C C C C G G G G C G C C C C G C G C G C C C G C G C C C C C C C C C C C C G G C G C G G C G C C C G C C G G C C G C G C G C G C G G C G C C C C G G C C C G C C C C C C C C C C C C C G C G C C C C C G C G C C C C G C C C C G G C C C C C C C C C C C C C G C C C G C C C G C C C C G C G C G C C C C G C C G C C G C G G G C C C G G G C G G G C C C C C C C G G C G C C C G G +C C C C C C C C C G C G G C C G G C C G C G G C C C G C C C C C C G C C C C C C G G G C C G C G G C G G C G C C G C G G C G C C C G G C C G C G G C C C C G C C G G C C G C C C C C C C G C C C C C G C C C C G C G G G C C G C G C C C C C C C C C G G C C C C C C C C C C G C C C C G C C G C C G G C C G G C C C G C G C G C C G C C C C C C C G G G C G C G G C C C G G G C G G C C C C C C C G C C C G C G C C G G C G C C G C C G G C G G C G G G G C C G G C C C G C G C G C C C C G C C G C C C C G C C G C G C C C G G C C C C G C C C G G G G G C C C C C C G C G C C +T T T T T T T T T A T T A T T A A T T A T A A T T T T T T T T A T A T T T T T T A A A T T A T A A T A A T T T T A T A A T A T T T A T T T A T A T T T T T A T T A A T T A T T T T T T T T T A A T T A T A T T T T A A A T T A T A T T T T T T T T T T T T T T T T T T T T T A A T A T A T T A T T A A T T A A T T T A T T T A T T T T T A T T T T T T A T A T A A T A T A A A T A A T T T T T T T T T T T A T T T T A A T A T T A T T A A T A A T A A A A T T A A T T T A T A T A T T T T A T T T T T T T A T T A T A T T T A T T T T T A T T T A A A A A T A T T T T A T A T T +A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A 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G G G G G G C G G G G G G G G G G G G C G G C G G G G G G G G G C G G G G C G G C G G G G G G G C G G G G G G G G G G G C G G C C C G G C G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G +T T T A T A A A A A T A A A A A A A A A T A A T T A A A T T A A T A A A A T T T T A A T A A T A A A A A T A A A A A A A T A T T T A A T A A T A A T A T A A T T A A T T A T A T A T T A A A A A T A A T A T A A T T T A T T A T T T T A A T A T T A T A A A A A A T A A T T A A A A T A T A A A T A A T T A A T T T A A A A A A T T T A A A T T T A A A T A A A A T A A A A A A A A T A T A T A T A T T T A T A A T A T A A T A A A T A A A A T A A T T T A T T A T T T A A A A A A T A T T T T A A A T A A T A A T A T T A A A T T T T A T T T A A T A A A T T T A T A A A T T +A A A A T T A T A T T T A A A T A A A A A T A A A T T T A A A T A T A A T A A A T A A A A A A A T A A A A T A T T A T A A A T A T A T A T T A T A A T A A A A A T A A A A A A A T A A A A A 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T T T T T T T T T T T A T T A T T A T T T T T A T T A A A T T T A T T T T T A A T T T A T T T T T A A A T T A A T T T T T T T T T T A T A A T T T A T T A A A T T A T T T T A T T T A T T A T T T T A T A A T T T T T T T T T A T T T T T T T T T T A A T T T T T A T T T T T T A T T T T T A T T T A T A +A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A +C C G G G C C C C C G C C C C C C G C C C C C C C G C C G G C C C C C C C G G G C C G G C C C C C C C G C C C C C G G G C C G G G C C C C C 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T T T A A A T A T A A T A A A A T A A A A A A A A A A A A A T A A T A A A A T A A T T A A T A A T T A T A T A T T A T T T T A A T A T A A T A T T A A A A T T T A A A T T A A T T A A T A T A A T T A T T T A A T A A A A A A A A A A A A A A A A A A T T A A T A A A A A A A T A A T A A A T A T A A A A T A T A A A A A T A A A A A A A A A A A A A A A A A A A T A T T A A T A T T A T A T T A T T T A A T T A A T T A A T A T T T T A A T T A A A A A A A A A T A T T T T A A T A A A T A A T A T A T T T A T T T T T T T A T A T A T A T A T A A A T T T +A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T A T T T A T T T T T T T T T T A T A T T T T T T A A T T T T T T T T T T T A A A T A T T T A T T T T T T T T T T T T T A A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T A T A T T T T A A T T T T T A T T T T T T T T T T T T T T T T T T T T T A T T T T T T A T T T +G G G G G G C G G C G G G G G G G G G G G G G G G G G G G C G G G G C G G G G G G G C G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G C G G G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C G C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T T A T T A T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T A T T T T T T T T T A T T T T A T A T T T T T T T T T T A A A A T T A T T T A T T T T T T T A T A A T A A A A T A A T T A A T T A T A A A A T T A T T T T T T T T T T A T A A A T T T A T T T A T A T A A T A A T T T T A A A T T A A A A T T A A T T T T T T A T +G G G C G G G C G G G G G G G G G G G G G G G G G C G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G C G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G C G G G C G G G G G G +C G G G G G G G G G C G G G G G G G G G G G G G G C G C G G C G G G G G G G G G C G G G G G 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T T T T T T T T T A T T T T T T T T A T A T T T T T T T T A T T T T T T T A A T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T A T T T T A T T T T T T A T A T T A T T T A T T T T T T T T T T T T T T T T T T T A T T A T T T T T T T A T T T T A T T T T A T A T T T A T T T T A T T T T T T T A T T T A A T T T T T T T T T T A T T T T T A T T T T T T T A T T A T T T T T T T A A A T A A A A T A T T T T T T T A T T T T T A T A T T T T T A T T A T T T A T T T T T T T T T T T T T T A A T T T T T T T A T T T +T T T A T T A A T A A A A A A T A A A A A A A A A T A A A T A A T T T A A A T A T A A T T A T A T T T T A A A T A A A T T A A T A T A A T T A T T T T A A A A A A T T T A A T A T T T A T T A A T T T T T A T A T T T T A T A A A T A A A A A A A A T A A A A T A A A T A A T T T T A T T T T T T A T A A T A T T A T A T T T A A A A T A A T A A T T T T T T A A T A T A A A A T A T T A T T A T A T A A A T T A T T T T A T T A A T T A A T T T A T T T T T T A A T T A A A T A A A A A T A A A T 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G C C G C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C G C C C C C C G C C C C C G C C G C G C C C C C C C C C +T A A T T T A A A T T T A A T A T A T T T T T T T A T T T T T A A A T T T T T T A T A T T T T A T T T A T T T A A T T A A T T T T T T T T T T T T T T T T T T T T A T A T T A T T A A T T T T T T A T A T A T T T T T T T A T T T A T A T T T T T T T T T T T T T A T T T T T T A T T T T A T T T T T T A A T T T T T A A A T T A A A T T A T T A T T T T A A T A A A T T T A T T A A T T A T A A T T A T T T T T T T T T T A T T T T T A T A A A T A T A A T A T T T T T T T A A T T A T T T A A A T T T A T A A T T T A T A T T T T T T T T T T T T A A T T T T T T T A A T A +A A A A T A A A A A A A T T A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A T T A A A T A T A A A T A A A A A A A A A A A T A T A T A T A T A T A T A A T A A A A A A A A A A T A A A A A A A A A A A A T A T A A A A T A A A A A A A A A A T T A A A T A A A A A A A A A A T T T A A A A A A A A A A A A A A A T A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A A A T A A A A A A A A T A T A A A A A A +C C C C C C C C C C C C C C C C C G C C C C C C C G C C C G C G C C C C C C C C G C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C G C G C C G C C C C C C C C C C C G G C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C +C C C C G C C C C C C C C C C G C C C C C C C C C G G C C G C C C G C C C C C C C C C C C C G C C C G C C C C C C G C C C C C C C G C C G G G G C C C C C C C C C C C G C C C G C C G C C G C C C C C C C C G C G C G C C C C C C C G C C C C C C C C C C C G C C C C G G G C C C C C C C G G C G C C G C C C C C C G C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C C G C C C C C C +T A A T T T A A A A A A A A T A A T A A A A A A A T T T A A T A A A T T T A A A A A A A T A A A A T A A T A T A A T A A A A A A A A A A T A T A A A A A A A A A A A A A A T A A A A A A A A T T A A A A A A T A A A A A A A A A A A A A T T T T A T A A T T T A T T A T T A T A A A A T A T T T A T T T A A A A A A T A A A A T A A A A A A A A A A A T A A A A A T A T A A A A A A A A A A A A A A A A A T T A A A A A T T A A A T A A A A A A A A A A A A A A T A A A T A T A A T A A A A A A A A A A T A A A A A A A A A A T A A A A A A A T A A A A A T A A A T A A A T A A +A A T A A A A A A A T A T T A A A A A A A T T A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T T A T T A T T A T A A T A A A A A T T T A A A T A A A A A A A A A A A A A A A A T A T A T A A T A A A A A T A A A T A A A A A A A A T T A A A A A A A A A A A T A T A A A A A A A A A A A T A A A A A A T T A A A T A T A A A A T T T A A T T A T A A A A A A A T A T T A T A T A A A A T A T A A A A T T A A A T A A A T T T T T T T T T A A T A A A A A A A T T A T T A T A A T A A A A T A T T A A A A A T A A A A A T A A A A A T A A A A T A A T T T A A A +G C C G G G C C G C C C C C G G G G G C C C C C C G G G C C G G G G C G G C G C G C G G C C G C G G G G G C G C C C C C G C C G C G C C C G C G G C C C C C C C C G C G C G C G C G G C G G G G C C C G C C G C G C G C C C C C C C G C G G G G C G C C G G G C G G C G G G G C C C G C G G G G G G G G C C C C C C G C C C G G G C G C C G C C C C C C G C C C C G G C G G C C C G C C G C G C C G C G C G C C G C G C C G C C C G C G C C C C C C C C C C C C G C C C G G G C C G C C C C C G C G G C G C C C C C G G C C C G C C C C C C C G C G C G C G C C C G C C C G C C +G C G C G G C C G C C C C G C C C C C C C G G C G G C C C C C C C C G C C C C C C C C C G C G C C C G C G C C C C C C G C G C C C C C C C C C C C G G G C C C G C C C C C C C C G C C C G C C C G G G C G C C C C C C C C G C C C G C C C G G C C C G G C C C C C C C C G C C G C G C C C G G C C C C G C G C C C C G C C G G G C G C G C C C C G G G G C G C C C G C G G G C C G C C G C G C C C C C C G C C C G C C C C C G C C C C C C C G G G C G C G C C G C C C C C C C G C C G C C C C C C C C C C G C C G G C G G C C C C C C C G C C C C C C C C C C G C G G G G C C C +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T A T T A T T A T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +T A T A T T T T A T T T T T A T T T T T A T T T T T A A T T A T T T T A T T T A T T T T A A T T T A T T A T A T T A T T T T T T T T T T T A T T T T T T T T A T A T T T A A T T T T A T T T T T T T T T T T T T T A T T T T T A T T T T T T T T T T T T T T T T T T T T A T A T A T T A T T T A T A A A T T T T A A T T T T T A T T T T T T T T T T T A T T T A A T T A T A T A T T T T T T T T T T T T T A T A T T T T T T A T T A A T T T T T T T T T T A A T T A A A A T A T T A T T T T T T T T T T A T T T T T T T A T T T A A A A T T A A T T T T A A T A T T T T T A A T +C C G G G G G G C G G G C G G G G G G G C C C G C G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G G G G G G C G G G G G C G G G G G C G C G G C C C G G G C G G G G G G G G G G G G C G G G G G C G C G G G G G C G G G G G G G G G G G C G G C G G G C G G G G G G G G G G G G G G G G G G G G C C C G G G G C G G G G G G G C G G G G G G G G G G G G G G C G G C G G C G G G G G G C G G G G C C G G C G G C G G G C G G G G G G G G C G G C G G C C C G C G G G G G G C G G G G G G G G G G G G C G G C G G G C C C G C G C G G G C G G G G G G C C G G G G G +C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C C C C C C C G C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C G C C C C C C C C C C C C C C +T T A T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T A T T A T T T T A A T T T T T T A T T T T T T T T A T T A T T T T T T T T A T T T T T T T T A T T T T T T T T A T T T T T T T T T A T T A T T T T T A T T T T T T T T T T T T T T T T T T T A T T T T A T T T T A T A T A T T A T T T T A T T T T T T T A T T A T T T A T T T T A A T T T T A T A T T T T T T T T T T A T T T A T T T T T T T T A T A T T T T T T T T T T T T T A T T T T A T T T T A T T T T T T T A T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T A T T +A T T T A A T T A T A A T T T T A A A A A A A A A A T T T T T T T T T A T T A T T A T A A T T A T T A T T A T A A A T T A A A A A T A T A T A A A A T A A A A A A T T T A T T T A T A T A T A A T A T A T A T T T T T T A T A A A T T A T A A T T T T T T T A T T T A T A T T A T A T A A A A T A T A T A T T T T A A T T T A A T T T A T T T A T A A A A T A T T A T A A T A T A A A A T T A A T T T T A T T T T A T T T T A T A T T T A A T T T A T T A T T T T A T T T T T T A T A A A T A T A T A A T T A A T T T T A T T T T A A T T A A T T T A T T T A T T A A A T T A A +C C C G C C C C C C C G G G C C C C C C G G G C G C G G C C G G C C C G G C C G G C G C G C C C C G C G G C G G C G C C C G G C C G C C C C C C C C G G C C G G G G C C G G C C G C C C C C C C C C C C C C C C C C C G C C G G C C C C G G G G C G G C G G C G G C C G G C C C C C G C C C C C C G C G C C C C C G C C G C C C G G C C C G C C G C C C C C C G G C G C C C C G C C C C C C C C C C C G G G C C C C C G C C C C C G C C C C C C C C C G C C C C C G C C G C G C C G G C G G G G C C G C C C G C C C C C C C C C C G G G C C G G C C C C C C C G C C G C C C G G +G C C G C G C G G G C G G G C C C G C G G G G C G G G G G C G G G C C G G C C G G C G G G C C C C G C G G G G G C G C C G G G C C C G G C C G C G G G G G C G G G G C G G G C G G C G C C G C C G G C C G C C G G C G G G C G G G C C C G G G G C G C C G G G G G G G G G C G C C G G G C C G G G G G G G C G G C G G G G C C G G G C G C G G G G G C G G C G G G G G C G C C G C C G G G C G G C C G G G G G C C G C G G G G G G G C C G C C C C C C G G C C C G G C C G C G C G G G G G G G G G C G C G C G G C G C G G G G C C G G G C G G G G C C C G G C G G G G C C C G G +T T T T T T T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +T T T T T A T T T T T T T T T T T A T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T A T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +G G G G G C C G G G G G G G C C C G C G G G G C G C G G G C G G G C C G G G C G G C G G G C G G G G G G C G G G G C C C G G G G G C G C G C G G C G G G G C G G G G C G G G G C G C G C C G G G G G C G G G G G C C C G C C G G G C G G G G G G G G C C G G G G G C G G G C G G C G G G C C G G G G G G G G G G C G G G G C G G G G G G C G G G G G G G G C G G G C G C G G C G G G G G G C G G C C G G G G G C G G C G G G G G G G C C G G C C C G C G G C C C G G C C G G G C G G G G G G G G G C G G G C G G C G C G G G G C C G G G G G G G G C G G C G G G G G G G C G G G +C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C G C C C C C C C C C C C G C C C G C C C C C C C C C C C C C C G C C C C C C C C 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T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T +T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T +C C C G G C G C G C G G G G C C C C C C G G G C G C G C C G G C G C C G G C C G G C C G G G G G C G C G C G G C C G C C C G G C G C G G C C C G G G G G C C G G G C C G G G G G G C C G C C C C C G C C G C C G C G G G C C G G C G C C G G G G C G C G G G G G G C C G G C G C G C G G G C G G C G G G C C C G G G G C G C G G G C C G C C G G G C C C G C C G G C G C C C C C G C G G C C C G C C C G G G G G C C C C G G C C G G G C C C G G C G C G C G G G G G G G G C G G C G G C C G G C C C G C G G G C G C C G C C G C G G G G C C G G C C G C G G G G C G G C C C G G +C C C C C C C C C C C C C C C C C C C C C C C G C C G C C C G C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C G C C C C C C C C C 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A A A A A A A A T A A A A T T A A A T A A A T A A A A A T T T A T A A A A A A A A A A A T A A A A A A A T A A A A A T T A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A +C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G C G G G G G C G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G +C C C C G C C C C C C C C C G G G C G C C C C C C G G C C C G C C G G C C C C C C C C C G C C C G C C C G C C C G C C C G C C C C C C C C G C C C C C C C C C C C C C C C 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T A A A A A A T A T A A A A A A A T A A A A T A A A T T A A A T A T A A A A A A A A A A A T A A A T A T A T A T T T A A T A A A A T A A A A A A A A T A A A A A A A A A T T A T A A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A T T A A A A T A T T A T A A A A A T A A A A A A A A T A A A T A A A A A T A A A T T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A A A A A A A A A A A A A T A T T A A A T A A A A T A A A A A A T A A A A A +C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C G C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C 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T T T T T T T A T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T +T A A A T A A A A A A A A A T T A A A A A A A A A A A A A T A A A T A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A T A A A T A A A A A A A A A A A T A A A A A T A T T T T A A A A A T A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A A A A A A A A A A A T A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A T T A A A A A A A A T A A A A A A A T A A A A A A A A A A A A A A A A A A A A A A A A A A A T A A A A A A A A A A T A A A A T A A A A A A A A A T A A A A A A A A A A A A A A +G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C G G G G G G G G G G G G G G G G G C G G G G G G G C G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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G C G G C C C G G C C G C C G G C G G C C G G C G G G G G C C C G C C G G G C C C G G C C C G C G C C G C G G G G G C C C C G C C C C C G G C C G C G C C C C C G G C G C G G G G C G C G C C C G G C C G C C G C C C G G C G C G C C C G G C C G C G G G G G G G C C G G C G G G G G C C G G G C C G C C C C G C G C C C G G G C C C C C C C G G G +T T T T A T A T T T T T T T A T T T T T T T T T T T T T A T T T A T T T T A T T T A A T T T T A T A A T A T T T T T A A A T T T T T T T T T A T T A T T A T T T T A T A T T A A T A T A T A T T A A T T T A A T T T T T T A T T T T T T T T T T A T T A T T T T T A T T T T T T T T T A A T T T T T T T A A A T T T A A T A T T T T A T T T T T T A T A T A T A A T T T T A T T T A T T T A T T T T A T T T T T T T T T A T T T A T T T T T A A T T T A T A T A A T T T A T T T T T T T T T T A A T T T T T T T T A T T T T T A T T T T T T T T A T T T T T T T A T T T A T T T +T A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A A +G C C G C C C C C C C C C C C C G G G C G G G G G G C C C C C C C C G C C C C C G C C C C C G C C C C G C C C C C C C C C G C C C G C G C C C C C C C G C G C G G C C C G C C C C C C C C C C C C C C C C C C G C C C C C C C G C C C G G C C G C C G C C C G C C C C C C G C C C C C C C C C G G C C C C C C C C G C C C C C G G C C C C C C C G C G C C C G C C G C C C C C G C C G G G C C C G C C C C C C G C C C G C G C C C G C G G C C C G C C C C C C C C G C C C G C G C C C C C C C C C C C C C C C C C C G G C C G C C G G C G C G C C G G C C C C G C G G G C C C C +G C C G G C G G G G G C G C G C C C C G G G G C G C C G G G C C G G C C C G C G C G G C C C C G C G G C G G C G G G G G G C C C C C G C C C G C C G G G G C C G G G G G G G G G C G C G C G C C G G G C C G G C C C C C C G C G C C G G C C C C G C C G C C C C C C G C C C C C C C C G G G C C C C C C G G G C C G G G C G C C C C G C C C C C C G C G C G C G G C C C G G C C C G C G C G C C C C G C C C C C C G C C G C C C G C C C C C G G C C C G C G C G G G C C G C C C C C C C C C C G G C C G C C C C C G C C C C C G C G G G C C G C G C C C C C G C G C G C G C G C +T T T T T T T T T T T T T T T T A A A T T T T T T A T T T T T T T T T T T T T T T T T T T T A T T T T A T T T T T T T T T A T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T T T T T T T T A T T T T T T T T T T T T T T A T T T T T T T T T T T T T T T T T A T T T T T T T T A T A T T T T T T T T T T T T T T A T A T T T T T A A T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T A T T T A T T T T T T T T T T A T T T T T A T A T A T T T T diff --git a/inst/bta12_hapguess_switch.out b/inst/bta12_hapguess_switch.out index 97d6d61..80d1495 100644 --- a/inst/bta12_hapguess_switch.out +++ b/inst/bta12_hapguess_switch.out @@ -19,948 +19,948 @@ END DESCRIBE_TASKS BEGIN GENOTYPES ANG_000001 # subpop. label: 1 (internally 1) -1 2 2 1 2 1 1 2 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 2 2 2 1 2 2 1 2 1 1 1 2 1 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 2 2 2 1 2 1 1 1 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 2 1 2 2 1 2 1 1 1 1 1 1 1 1 2 2 1 2 1 1 2 1 2 1 1 2 1 2 1 1 2 1 2 2 1 2 2 1 1 1 2 1 1 1 2 2 2 1 1 1 1 1 2 2 1 2 1 2 2 1 2 2 2 2 2 1 2 1 2 2 1 2 2 2 1 1 1 2 1 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 2 1 2 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 1 1 1 2 1 1 1 2 2 2 1 2 2 2 1 1 2 1 1 2 2 1 1 2 1 2 1 2 1 2 1 2 2 1 1 1 2 2 1 1 2 2 2 1 2 2 2 1 2 1 2 1 1 2 2 2 1 2 2 2 2 1 2 1 2 2 2 2 1 2 2 2 2 2 1 1 2 1 1 2 1 1 1 2 2 1 2 1 1 1 1 1 2 1 1 2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 1 1 2 1 2 1 1 1 1 1 2 1 2 1 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 2 2 1 2 2 2 1 2 2 2 2 1 1 2 1 2 1 1 1 1 2 1 1 1 1 1 2 2 2 1 1 2 2 2 2 2 1 1 1 2 2 1 1 2 2 2 1 1 2 1 1 2 2 1 1 2 1 2 1 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 2 2 2 2 1 1 1 1 2 1 2 2 2 1 2 1 2 2 1 1 1 2 2 2 1 1 1 2 1 2 2 1 2 2 2 2 1 2 1 2 1 1 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 1 1 2 2 2 1 1 1 2 1 2 1 1 1 1 2 1 2 2 1 1 1 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 1 2 2 1 2 1 1 2 1 2 2 1 1 2 2 1 2 1 1 1 1 1 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 1 2 1 1 2 1 2 1 1 2 2 1 1 1 1 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 2 2 2 1 1 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 2 1 1 1 2 1 2 1 2 2 1 2 1 1 1 1 1 2 2 1 1 1 1 2 1 1 2 2 2 1 2 1 2 1 1 2 2 2 1 1 2 1 1 2 2 2 2 1 1 1 1 1 1 1 2 1 2 1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 1 2 2 1 1 1 1 1 2 2 1 2 1 1 1 2 1 2 1 2 1 1 2 2 1 1 2 1 2 1 1 2 1 1 2 1 1 1 1 1 1 1 1 2 2 2 1 1 2 1 2 2 2 2 1 2 2 2 1 2 2 2 1 1 1 2 1 1 1 2 2 1 2 2 2 1 1 1 1 1 1 1 1 2 1 2 1 2 1 1 1 2 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2 1 1 1 2 2 1 2 1 1 2 2 1 2 1 1 2 2 1 2 1 1 1 2 1 1 2 1 1 1 1 2 2 2 1 2 1 2 2 2 2 2 1 1 2 2 2 2 1 1 2 2 1 2 1 2 2 1 2 2 2 1 +T G C A A C G T A C C T A G G T A C C A T G C T A G G T A C C A T C C A A G G A A G G A A G C T T G C A T C G T T C C T A C C A T C C T A C C T T G C T T G C A T G G T A C C A T C G A T C G T A C C A T G G T T C C A A C G T T G C A A G G A T G G A T G C T T C G A T G C A A C C T T G C T A G G T T G C A A G C A T C C A A G C T T C C A T G C A T C C T T G G A A G C T A C C A A G C T T C G A A C G A A G C A A G C A T G G A A G G A A C C A A C C A A G G A T G C A T G C T T G C T T G G T T C C T A C C T A G G T T G C T A C C T A G C A T G G A A C G A A G G T T C G A T G G A A G G T A G G A T G C T T C C T T C C A A C G A T C C A A C G A A C G T A C G T A G C T A C C T A G G T A G G T A G C A T G G T T C G A A C G A T C C T A C G T A G C T T C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G T T G G A A C G T A G G A T C G T A C C A T G C T T C G T T G G A T C C A A G G A T C C T T G G T A G G T A C G T T G C A A C G T T G C A T G C A A C G A T C C A A G G T A C C A T C G T A C C A T G G T T C C T T C G A T G G T T G C T A G G T A C C T T G C T A G C A T G G A A G G T A G G A A C G T A G C A A G G A T C C A A C G A A C C A A G G T T C G A T G C A T C G T T C C T A C C A A C G T A G G A A C G T A G C A T C G A T C C A A C C T A G C A A C G T A G C T T C C A T G C A T C G T A C G A T C C T T G G A T G G T T G G A A G G A A C C A T G G A A C G A T C G A T G C T T C C A A G C T T G C T T G C T T C G T T C G T A C C T A C G A T C G A T G G T T G G A T G C T T C G T T G C T A G C A A G G T A C C T T C C T A G G T A C C T A C C A A G C T T G C T A C G A T G C T T C G T A G C T T C C T T G G T A C G A T G G T T G C T A G C A A C C A A G C T T G G A A G C T A G G A A C C A A C C T T C G A A C C T A G G T A G G T T C G A A G G A T C C T A C C A T G C T T C C T T C G A T C C A T G G T A C G T T C C T A C C A A G G T A C G T A C G A T G C A T G G T T G G T A G C A A C G A T C G T T C G A T C C T A G G A A C G A A C C T A G C A A C G T A C C A A G G T A G G T A G G A A C G A T C G A T G C A T G C A T C C T T C C T T G C A T C G T T G C A A C C T T G C T T G C A A G G A A G G T A C C A T C C T A C C T A G G A A G C T A G C T A G C T T G C T T G G A A C G A T G C A A G C A A C C T T G G T A C G A T G C T T G C T T C G A T C G T A C G T T C C A A G C A A C G T T C C T A G C T A G C T T C G A T G C A A G C A T C C A A G C T A G C T T C C T A G C A A C C A T C G A A G C T A G C A A G G A A C C T T G C T T C G T A C C A A G C A A C C A A G C A A C C A T C G A A G C A T C C A T G C A T G C A A G C T T C C T A C C A A G C T A G G T A C G T A G C A T G C A A G C A T C C A A C C T A C G A A G C T T G C T T C G T T C G A A C C T T C C T T C C A A G C A A C C T T G C T T C C T A G G A A G C T A G G T A G G T A G C A A C G T +T G C A A C G T A C C T T C C T A C C T A G C T A C C T A G C A A G C A A G G T T G C T T G C T T G C A T C C T T C G T T G G T A C C A A G C A T G C A A C C A T G G T T G C T T G C T T G G T T G C A T G G T T G C A A C G T T G C A A G G A T G G A T G C A A C C T T G C A A G C A T G C A A G C A T G C T T C G A T C C T A C C A A G G A T G C A T C C A T C G A A G C T A C G A A G C T T C G T T G G T A G C A A C C A A G G T T G C T A G C T A C G A A G G A T G C A T G C T T G C T T C G T T C C T A C G T A G G T T G G A A C G A T G C T A C G A A C G A A G G A T G C A A C G A T G C T A G G T A G C T T G G A A G G A A C C T T G C A A C G A A C G T A C G A A C C T T G G A A G G T T C C T A C G T A G C T A G G T A C G A T C C T A C G T T G G T T G G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A G G T T G G T T G G T T G G A T C C T A G C A T G C A A C G A A G G T A C G T T C G T A C G T T G G A A C G T A G C A T G G A T C C A A G G T A G C T A C C A T G G T A C G T T G C A T C G A A C C T A G G T T G G A T C C T T C C T T C C T T C G T A C C A T G G T T G C A A G G A A C C T A C G T A G C A A G C T A C G T T G C A T C G T T C C T A C G T A G G A A C C T T G G A T G C T T C G A T G C T A G G A T C C T T G G T T C C T T G C A A C C T T G G T A C C T T C G T T C C T T G G T T G G T T G C A T C C A T C G A A G C T A G C A T C C A A G C A A G C T T G C T T G G A A G G T A C G T A C G A A C G T T G G A A G C A T C G A A G G T A C C A A C G T A G C A A C C A A C C T T C C T A G G A A G C T T C C A A G C T T G C T A G C T A C G A T C G T A G C T T G G T T C C A A C G A A G C A T C C T A C G T A C C A T G C A A C G A A G C T A G C T A C G T T G G A T G C T A C C T A C G A T G G T T C G T A C G A A C C T T C C A A C G T T G C A T G C T T C C A T G G A T C G A T G G T T G C A A C G T A C G T A C G A T G G A T C G T A G G T A G C A T G G A A C C T T C G T T C C T A G C T A G 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A A C G T A C C T T C G T A G G T A G C T A C C T T C C T A G C T T G C T T C C T A G G A A C G T A G G T A C C A A G C A T C C T A G G T A G G A A G G T A C C T +T G G A A C G T A C C T T C C T A C G T T C G A A C G T A C C T A C C A A G G A T G C T T C G T A C G T T G G A A G C T T G G T A G C T A C C T T G C A A C C T T G G T T C C A A C C A T G G T T G C T T G C T T G C T T C C A T G C T A G G A A G G A T G G A A C C T T C G T A C C A T C C T A C G T T C C A T C C A T C C T A G C A T C C A T C G T T C C T T G C A T G C T A C C A A G C T T C G T T G G T A G C A A C C A T G G A A G G A A C C A A C G A A G G A T G C A T G C T T G C T T C G A T C G A A C C A T C C T T G C A A C G T T G C T A C G A A C G A A G C T A C C A A C G A T G G T A G G A A G C T T G C T T G C A A C C A T G G T T C C A T C G A A C G A A G C T A C G A A G G T T C C T A C G T A G C T A G G A A C G A T C C T A C G T A G C T T C G T A C G A A G G A A C C A A G G A T C G T T C C T T G C A T G C A A C C T T C G T A G C 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A T C C T T G G T T G G T A G G A A C C T T G C A T C C T T G G A A G G T A G G A T G G T A C G T A G C T T G C A T G C A T C C T A G G T A C C A T C G T A C C T A G C T A C G T T G C T T C G T T G C A A G G T A G G T T G G A A G C A T C G T A C G T A C C A T G C T T C C A A G G A A C C A A G G A A G C A A G G T T C G T T G C A A G G T T G G A A C C T A G G A A G C A T C G A T G G T T G G A T G C T T G C T A G C A A C G T A C G A T G C A A C C T A G C A T G C A T C C T T G G A T G C A A C C A T G C T T C C A T C G A A G C T A C C A T C C A A C C T A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C C A T G G T A G C T A C G T T G C T A G C A A G G A A C C T T C C T A G G A A G C A T G G T T G C T T G C T A C G A T G C A A G C A A G G A T G G T T C C A A C G A T G G T A C C A A C G T A C C T A C G T A C G A A G G A A G C T A G C T T G C T T C C A A C C T A C G T A C G T T C G A A C G A A C C T A G G A T G C T A C C T A G C A T C C A T G G T A C G T T G G A A C G A T G G 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T G C T T C C A T C G A T G C A A G C A A G G A A C C T A C G A A G C T A G C A T G C A A C C A A C C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C G T T G C T A G C A A G G A A C C T T C C T A G G A A G C A T G G T T G C T T G C T A C G A T G C A A G C A A G G A T G G T T C C A A C G A T G G T A C C A A C G T A C C T A C G T A C G A A G G A A G C T A G C T T G C T T C C A A C C T A C G T A C G T T C G A A C G A A C C T A G G A T G C T A C C T A G C A T C C A T G G T A C G T T G G T A C G A A G G T A C C T A C G A T G G A T C G T A G G T A G C A T G G A A C C T T G C A A G C A A G G T A C C T T G C T A C G T T G G T T G C T A G G T T G C T A G G A A C G T A C C T A C C T T G C T T C C T T C C T T G C A T C G T A C C A A C C T A C G T T G C A T G G A T G C T A G G A A C C T A C C T A G C A A G G A A C G T A G C T A C C T T G C A T C G A T G C A A G G T T G G A T G G A A G G A T G C T A C G T T G G A A G G T A C G T T C C T T C C T A C C A A C C T 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A A G C A T G C T A C C T A G C A T C G A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T G G A A C C A A G C T A C G A A G C T T G C A A C C T A C G A T G G T T C C T A G C A A C G T T C C A A C G T T G C T T C G A A C C A T G G A A G G T A G G T A C C A A C C T A C C T A C G A T G G A T G G T A G C A T C G T T G G A A G G A A G C A T C C T A C G A A G C T T G C T A G G A T G G A T G C A T C C A A G G A A G G A A C G T A C C T A G G T A G G A T G G T A C C T T G C A T G G T A C C A A C C T T G C T A G G A A G G A A C C T A C C A T C C T A C C T A G G A T G C T A C C T A G C A A C G T A G C A T C G A T G C T A G G T T G C A A G G T A G G A T G C A A C C T T G G T A G C A A C C A T C C T T C G T A G G T A G C T A G C A T C C T A G G A T G C T T G C A A C G A A G G T A C G T T G G T A G C T A C C A T G C A A G C T A C G A A G G T T C G A T C C A T C G A T G C T T C C T A C C A A G C A T C C A T C G A T C C T A G G A T G C A A C C A A G C T T C C T A C C T T C C A A G G T A C G T A G C T T G C A T G C A T C C A A G C A A C C A A G C T A G C A A C G A A C C T A G G T T C C T T C C T T G G A A C G A T G C T T G G T A G G A A C G A A G C T A G G T A G C A A C G T AUB_9066 # subpop. label: 2 (internally 2) -2 2 1 1 2 1 1 2 2 1 1 1 1 2 2 1 2 1 1 2 2 1 1 1 1 2 1 2 1 1 2 2 1 1 2 1 2 2 1 2 1 2 2 2 1 2 2 1 2 1 1 1 2 2 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 2 1 2 2 1 1 2 2 2 1 2 2 2 1 1 1 2 2 2 2 1 1 2 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 1 1 2 2 1 2 1 1 2 2 1 1 1 1 2 2 1 2 1 1 2 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 1 1 1 2 2 2 2 1 2 2 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 1 2 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 2 1 1 2 2 1 2 2 2 1 1 1 2 2 2 1 2 2 1 1 1 2 1 1 1 2 2 1 2 1 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 2 1 1 1 2 1 1 1 2 1 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 2 2 1 1 2 2 2 2 2 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C C T T C C A A G G T T G C T T G C A A C G A A G G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A A G G T T G C A T C G T A C C T T G G T A C G T A G G T A G G A T G C T A C G T T G C A A G C T T G C A A G C A T G C T A C G A T C C T T G G A A G G A T C C T T G G A A G G T A G C T T G C A A G C T T C G T A G C A A G C A A G C A A G G A T G C T A G C T A G C A A C G A A G C A A G C T A G C T A G G T T G G T A C C T T C C T T G C T T C G T A G G T A C G A A C G A A G G T T G C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G T T G C A T C C T A C C T A G G T A C G T T G G T T C G A T C G A T G C A T C G A A G G A A G C T A C G T A G C A A C C T T G C T A C G A A G C T T G C A T G G T T G G T T C G T T C G A T G G A A G C A A G G A A G C A T C G A A C C T A C G T T C G T A C G A A G C T A C C A T C G T A C C A T G C T A C G T T G G A T C C A A G G A T C C T T G G T A G G T A C C T T G G A A G C T A G G A A G C T T G G A T G G A T C C A T G G A A G C T A C C A T G G T A C G T T G C T A C G T T G C T A C G T T G G A T C C T T C C A T C C T T G C T A C C A T G C A T G G A T G C A A C C A A G G T A G C A A C G A T G C T A G C A T G G T T C C T A C C T A G G A T C G A A C C A T G C T T C G A T G C T T G C T A G G T T C C T T G C A A G C T A G C T T G C T A G C A T C C T T C C T T G G T T G C A A G C A A C C A T C G A T C G A T G C A T C C A A C C A A C C T T G G A A C C A A G G T A G C A A G G T A C G A T G G A A C C T A G C A T G C T T C C T T G C T A C G A T C C T A C C T T C C T A G G A A C G T T C C A A C C A T C C T A G C T A C C T A G C A A G C A A C C A T G G T A C G A A G C T T C C T T G C T A G C A T G C T A C C T T C C T A C G A A C G T T G C T A C G A T C C T A C G A T G G T T C G T A C G A A C C T A G G A T G C T T C C A T C G A A C C A T G G T A G G T T G G T A C C A A C C T A C C T A C G A T G C A A C G T A G G T A G C A T G G A A G C T A C G A A G C T A C G A A C C T T G C T T G C A A C G T T G C A A G G T A G G A T C G A A C C A A C C T A G G T A G C A T G C T T C C T T G C A T C C T A C C A A C C T T G C T A G G A T G G A T C C T T C C A A C C T T G C A T G G A T G C T A C G T A G C T A C C T T G C A T C G T T G C A T G G T T G G A T G G A A G G A A G C A A C C T T C C A A G G T A G G A T C C T T C C T A C C A T G C A A G C T T G C T T G C T A C C A T G C T A C G T T G G T T C G T T G G A A C C A A G G T T G C A A G C T A G C A T C G A T C G A T C C A T G G T T G C T T C C A A C C T A G C A T C G A A C C A A G C T A G G T A C C A T C G A A G G T T C C T A C G A A G C T T C C T A C G A T G C A T G G A A G C T T C G A T C C A A C C A A G C T T G C A T G G T T G C T A G C T T G C T T C C A A G C T A C G A T G G T A C C A A G C A A G C T A G G T A G G T A G G T A C C T +A G G A A G G T T C C T A G C T A C C T A G G A A G G T T C G T T C C A A G G T T C C T T G C A A G G T T C G A T C C T A C C A T C C T A C C T T G C T T G C A T G G T T G G A T C C T T G G T A C G T T G G T A 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C C T A C C T A G C A A G C T A G C T A G C T A C C T T G G A A C C T T G C A A G G T T G G A T G G A A G G A T G C T A C G T T C G T T C G T A C C T T C C T T C C T A C G T T C C A A C C T A C C T T G G A T G C T A G C T A G G A A C G T T G C T T G C T A C C T T C G A T C G T A G C T T G G A A G G T T C G A T C C A T C G A T G C T T C C T A C C T A C G T T G C A T C G A A G C A T C G T A C C A A C G T T G G T T C G A A C G A A G C T T C C T A C G A T G C A T G G A A G C A T C C T T G C T A C G A A G C T A G C A A C G A A C C T A G G T T C C T T G C A A G C A A C G T A G G T T C C A A G C A A C C A T G C T A G C A A G G T A C C T AUB_9067 # subpop. label: 2 (internally 2) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 1 2 2 2 2 2 1 2 1 2 1 1 1 2 1 1 2 1 2 2 1 1 2 2 2 2 1 2 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 1 2 1 1 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 2 2 2 2 2 2 2 1 1 1 1 1 2 1 1 2 1 1 1 1 2 1 2 2 1 2 2 1 2 2 2 2 1 2 2 2 2 1 2 2 2 1 1 1 2 2 2 2 1 2 2 1 1 1 2 1 1 1 1 1 1 1 1 2 2 2 2 1 2 2 2 2 1 2 1 1 1 2 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T T C C T A C G A A G G A A G G T T C C A T C C T T G G A A G G A T C C T T G C T A C C A T C C T T G G T T C G A A C C T A G C T T G C T T C C T A G C A A C C T A G C A A C C A A G C A A G C T T G C T A C C T A G G T A C C T +A G G A A C G T A C G A T G C A A C G T A C G A A G G T T G G A T C C A A G G A A G G A A G C A T G G A A C G A A G G T A C C T T G C T A C C T A G C T T G C A T G G T T C C T A C C A T G G A A C C T T G C A A G C A T C G T A C G T A G G T A C C A T G C T T C G T T G C A A C C T T C G T A G G T T G C T T C C A T C C A A G C A T C C A A C C T T C C A T G G A T G G A A G C A A G C T A C G T T G G A A G C A A G C A A G C T T G C T A G C T A G C A T C G A T G C A A G G T A G C A A G G A T G C T A C C T A G G T A C G A A C G A A G G A T G G T A C G A A G C T T G C A T G G A A G G T T G G T A C C T A C C T T G C A A C G A T G C T A C C A A G G A A G G A T G C T A C C T A G G T A G C A T C G T A G C A T G G T A C G T T G C A T C G T A G C T T C C A A G G T A G G A A C G 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A A G C T A C G A A G C T T G C A A C C T A G G T A C G A T C G A A G G A T C C T T C C A A C G T T C C T T C G A A G C A T G G T A C G T T G G T A C C A A G G T T C C T T G G A T G G A T G G T A G C A T C G T T G G A A G G A T G C A T C C T A C G A A G C T T G C T T G C A A C G T T G C T A G G T A G G A T C G T A C G T A C C T A C C A A G G A T C C T T C C A T G C A T G G T T G C A A C C T A C G T T G C A T G G A A C C T T C C T T C G A T C G T T G C A A G G A A C C T A G C T T G G T A G C A A C C A T G C A T G C A A G G T T G G T A G G A A G C T T G G T T C G A A G C A A C G T T C C T T G C A A G G T A G C T A C C T A G C T T C G T T G C A A G C A T C C T T G C T T C G T T G G A A C C A A G G T A G C A A G C T A G G A A G G A A C C T T C G T T C G T T G C T A C C A A C C T A C G T T G C A T G G A A G C T A G G T A C C T A G C A T G G A T C C T A C G A A G G A A C C T A G C T T G C T T G C A T G C T A C G T A G G A A C C A A G C T T G G T T C G A A C C T A G G T T C C T T C C T A G C 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C C T A G C T T C C A A C G T T C C A A G G A T G C T A C G A T G G T T C G T A G C A A G G A A G C A T G G A A G G T A G C T A C G A A C G A A G G A A G C A A C G T A G G T T C C T A C C T A G G T A G G T A C C T A G C T T G G A A C G T A G G T T G C T A C G A A G G T T G G T A G C T T C G A T G C A T C C T T G G T T C G A A C G A A G G A T G C T A C C T A G G T A C C T A G C A A C C T A C G A T C G A T G C A A C G T A G C T T C G T T C G A T G G A A C C T T C G A T C G T T G C T T G C A T G C A A G C T T C C T A G C A A G G A A G G A T G G T T G C T A G G A A C C A T C C T A G C T A G G A A G C A T G C A T G G T A C C A T G G T A C G A A C C A T C C T A G C A T C C T T C G A A G G T A G C T T G G T T G C T A G C T A C G T A C C A A G G A T C C T T G G T A G C T A C G A T G C T A C G T T G C T A C G T T G C T A C G T T G G A T C C T T G G T T C C T T G C T A C C A T G G A T C C A A G C T A C C T A G C T A G C A A G G T T C C T A G C A T C G T T G G A A C C A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G G T A C G T T G G T A G C T T G C A T C G T A G G A T C G T T G G A T G C T A C G A A G C T A G C A T C G A A G C T T G C A T C C A A C C A A G C T A G C A A C C T T C G T T C G A A C G A T C G T T C C A A G C A T G G A A C C A A G C A A G G T A G C A A C C T A C C T T G G T T G C T A G C A T G C T T C C A T G C T A C G T A C G A T C G A A G C T T G C T T G G A T C C A T C G A T C C T A G G T T C C A A G C T T G G A A C G A A G C T A C C T T G G A T G C A T C C T A G C A T C G T T G G A A C G A A C C T T C C A A C G T T G C T T C G A A C C A T G G A A G G T A G G A T G C A A G G T T C C T T C C A T G G A T G G T A G G A T C G T A C G A T C C T T G C A A C G T A C G A A G C T A G C T A C C A A C G T A C C A T G G T A G C A A G C T T G C A A C G T A G G T A G C T T C C T A C C A T G C A T G C A A C C A A C C T A C G T T G C A T G G A A G C T A C C A A C G T A C G A A G C A A G G A A C C A A G C T T G G T A G C A A C C A T G C A T G C A A G G T T G G T A G G A A G C A T G G T T C G T A G C A A C C A T C C T T C G T A G G T A C C T A C C T T G C T T G G A T G C A A G C A T C C A A G G T T C G T T G G A A C C A A G G T A G C A A G C A T G G A A G G A A C G A T G C A T C G T T G C T A G C T A C C T A C G T T G C A T C G A A G C T A G G T A C C A T C G A A G G T T C C T A C G A A G C T T C C T A C G A T G C A T G G A T G C T A C G T A G G A A C C A T C C T T G G T T C G A A C C T A G C T T G C T T C C T A G C A A C C T A G C A A G C T A G C T T G C A A G C T A C C A A G G T A C C T +A G C T A C C T A C G A T G C T A C G T A C G T A G G T A G C T T C C A A C G A T G C T T G G A T G G A A G G A T C C T A G G T A G C A T G G T T G G A A C C T T G G T T G G A T C G A T C G T A G C T T G C T A G C T T C C A A C C A A G G A T G G A T G G T A G C T T C G T T C C T A C C A A G C T T C C A A C C A T C C T A G C A A G C A T G C A T C C T T G G T A G C T A C C A A G C T A C G T A G C T A G C A A G C A A G G A T G C T A G C T A C G A A C C T T G G A A C G T A C G T A G G T T G G T A C C A T G G T T G C T T C G T A G G T A C G T A C G A A G G T T C C A T G G A A G G T A G G A T G C T T C G A A G G A A C G A T G C T A C G A A C G A A C G A T G C T A C C T A G G T A C C A A C C A T G G A A C C A T C G A T C C T A C C T A G C T T C G T T C G T T C C A T C G T T G G A T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G C A A G G A A G C A T C G A A C C T A C G T T C G T T G G A A G C T A C C A T G G T T C C A T G G T A C C T T G G A T C C A A G G A T C C T T G G T A G G T A C G A T G G T A C G T T G C A A C G T A G G A T G G A T C C A T G G A A G C T A C C T A G C T A C G T T G C A T C G T A G C A T G G T A C C T T G G T A G G T T C C T T C G T A C C A A G C A T G C A A G C A A C C A A G G A A C C A A G G T A G C T T G C A A G G T A G G A A C C T A G G A A C C T A C G T A G C A T G G A T C C T T G C T A C C T T G C T T G G T T C C T A C C T T G C T A G C T T C C T T C C A T G G T T G C A A G C A A G C A T C G A T C G A T G C A T G C A A C C A A G C T T G C T T G C T T C G T T C G T A C G A A C G T T G G A A G C A T G G A T C C A A C C A A G G T A G C A A C G T A C G T A C G T A G G T A G C A T C C A A G C T A G C T A C G T A C C A T C G A A G C A T G G T T C C A A C G A A G C T A C C T A G G T A C C A A G C T A C C T T C C T A G C T A C G A A G C T T G C A A C C T T G G T A C G A T C G A A G G A T C C T T C C T T G C A A C C T T C G A A C C A T G G A A G G T A G G T A C C A A C C T A C C T A C G A T G G A T C G T A G G T A C C T T G G A A G G A T G C A T C C T A C G A A G C T T G C T A C C A A C G T T G C T A G G T A G G A T C G T A C G T A C C T A G G T A G G A T C C T T C C A T G C A T G G T T G C A A C C T A C G T T G C T A G G A A C C T T C C A A C C T A G C T T G G A A G G A A C C T A G C T T G G T A G C A A C C A T G C A T G C T T G G A T G G T A G G A A C G A A C C T T G C A A G C A A C G A T C C T T C G T A G G T T C G T A G G T T G C A T G G A T G C A A C G T T C C T T G C T A G G T T G G A A G G T T G C A T G C T A C C T A G C A A G G A T C G A T C C A T C G T T G C T T C C T A C C A A G C A T C C A T C G A T G C T A G G T A C C A T C G T A G G T T C C T A C G A A G G A A G G T A G C T T G C T T G C A T G C T A C G T A C C A A C G A A G C T A G C A A C G A A G C A A G C T T G C T T C C T A G C T A C G A T G G T A C C A A G C A A C C T A G C T A C C A A G C T A C G T AUB_9072 # subpop. label: 2 (internally 2) -2 2 1 1 2 1 1 2 2 1 2 1 1 2 2 1 2 1 2 2 2 1 1 1 2 1 1 2 2 1 2 2 1 2 2 1 2 2 1 2 1 1 2 2 1 1 1 2 2 1 1 1 1 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 1 2 2 1 1 1 1 2 2 2 2 1 2 1 1 2 2 1 2 2 2 1 1 2 2 2 2 2 1 2 2 2 2 1 1 2 1 1 1 2 1 2 2 2 1 1 2 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 1 2 2 2 1 2 1 2 1 1 2 2 1 1 1 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 1 2 1 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 1 1 2 2 1 1 1 2 1 1 1 2 2 1 1 2 2 2 1 2 1 1 2 2 2 1 2 1 1 2 2 2 1 2 2 2 2 1 2 1 2 1 2 2 1 2 2 1 1 2 1 1 2 1 1 2 1 1 1 2 2 2 1 1 1 2 1 2 1 1 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2 2 1 2 2 1 2 2 1 2 2 2 2 1 2 2 2 1 1 2 2 2 2 2 2 2 1 1 1 1 2 1 2 2 1 2 1 2 2 2 1 2 1 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 1 2 +A G G A A C G T A C C A T G C A A C C T A C G A A C G T A C C T T G C A A G G T T C C T T C G T A C G A T C G T T G C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T T G C A T C G T A G C A A C G T A C C T A C G T A G C T T G C T A C G T T C G T T G C T T C C T A G G T T G C T T C C A T C C A A G C A A C C A T G C A T C C T T G G T A G C T T G C A A G C T A C G T T G G A A G G A A C C T A G G T A G C T A C G T A C G A A C G A A G G A A G C A A C G T A G G T T C C T A C C T A G G T T G G T A C C T T C C A T G G A A C G A A G C A T C C A A C G A A G G A A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A T G C T A C C T A G G T A C C A A C C A T G C T A G G A A C G A T G C T T C C T A G C T T C G T A C G A T G C A A G G T T G G T T G G A A G C T T G C A T G G T A G C A T G G A A C C A T G G A A G G A T C C T T C G T A G G A A C C T A G C A A G C T A C G A A G C A A G G A T C G T A C C A T G C A A C G T T G G A T C C A A G G T A C C T T G G A A G G T A G C T T C C T A C G T T G C A T G C A T G C A T C G A T C C T A G G A A G C T T C G A T G G T A C C A T G G T T C G T T G C T A C C T T G G T T G G A A G C T A C G T T G G T T C C A A G G T T G C A A G C A T G C A A G G A A G G T T C G A T G G T A G C A T C G T T G G A A C C A A G G T T C G A A C G A T G C T T G G A T C G T T G G A A G G T A C C T A G C A T G C A T G C A T C G T A G G T T C C T T C C T T G G T T G C A A G G A A G C A T C G A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C C A A G C T T C C T A C G T A G G A A G G T T G G A T G G T A G C A T G G T A G C A T C C A A G G T T C C T A G G A A C C T A G G T T G C T T G C T A C G A T G G A T C G T A G G A A C C T T G G A T G G A A G G T A G G T A G C A A G C A A C C T A G G A A G C T T G G T A C G T T G C T T G C A T C C T A G G A T G G T T G C T A G C A A C C T A G G A T C G T T G C T T C G A A C C A T G G A A C G A T G G T A C C T A G G T T C C T A G G A T G C A A C G T A G G T A G C A A C G A T C G A T G G A T C C T A G G A A G C T T G C T A G C A A C G T T G C T A C C T A G C T T G G T A C G A A C C T A G G T A G C A T G C T T C C A T G C T T C G T A C C T T G C T A C C T T G C A T G G A A C C T A C G A A C G T T C C T T G G A A G C T A G C T A G C T A C C T T G C A T C G T T G C A T G G T T G C A T G G T T G C A A C G A T C G A T C G T T C G T A C C T T G C T T C C T A C G T A C G A A G C T A C C A A G C A T G C A A G C A A C G T T G G T T C G T T C C T T C C T T C G A T C G A A C C T A G C A T C G A A G C T T C G A T G G T T G C T T C G A A C C T A C G A T G C A T C G A A G C A T C G T T C C T A G C A T G G T T C C T A C G T A G C T A G G T A C C A A G C A T C G A A C C A T C C A T G C T T C C A A G G T T G G T A C G A A C C T A G G T T G G T T C C T A G C A A C C T A G C A A C C A A G C A T C C T A G C T A G C A A G C T A C G T +A G C A A C G T A C G A T G G A T G G A A C C T A G G T A G C T T C C A A G G A A G C T T G C A A C G T T G G A A G C T A C C T A C C T A C C T T G C T A G C T T G G T T C C A A C C A T G G T T C C T T G C T T C C A T C C T A C C T A G C A A C C A T G C T A C G A T G C A A C C T T C G A A G G T T C C T T C C A T C C A A G C A A G G A A C C A T C G A T G G T A G G A T G C A A G C T A C G T A C C T A G C A A G C T A G G T T G C T A C C T A G C A A C G T T G G A A G C A A C G T A G G T T G G T A G C T A G G T A G G T A C C T T G C T A G C A A C C A A G G T T G C A T G G A A G G T T G G A A G C T A G G T T G G T A C G A T G C T A C G A A C G A A C G A T G C A T C C A A G G T A G C A T C G A A G C A A C G T T G G A T G C T A C G T A G G A A G G T A C G A T G G A A C G T A G G T T C G A A G C T T G C A T G G T A G C T T C C T A C C A A G G A A G G A T G G A A G C A T C G T A G C T A G C A A G C T A C G A A G G A T C G A T G C T A C C A T G G A A C C T T G G A T G C T T G G T A G C T T C G A A C G A T C G T T G G T A G C T A G G A A G G T A C C A T G G A T C C T A G G A T C G T A C G A T G G T A C G T T G C T A C G T T G C T A C G T T G G A T C C T A C C A T C C T T C G T A C C A A G G A T G C A A G G A A C C A A G G T A G C A A C G A T G C T A G C A T C G T T C C T A C G A A G C A A G C T A C G T T G C T T G G A T G C T T C G T A G G T A C G T A C G A A G C A T G C A T C G T A G C T T C C T T G G A T G C A A G C A T G G A A C C A T C G A A G C T A G C A T C C A A C C A A G C A A G C A T G C T T C G A T C C T T C C T T C G A T C C A T C C A T G G A A G C T T C C T T G C T A G C A A C C T A G G T T C C T A G G A A C C A T C C A A C C T T G C A A G C T A C G A T C G A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T G G A A C C A A G C T A C G A A G C T T G C A A C C T A C G A A G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G A A C G T A C C T A G C A A C C T A C C T A C G A T G G A T G G T A G C A T C G T T G G A A C G A T C G A A C C A T G G A A G C T T G C T A G G A T G G A T G C A A G G T T G C T T G G T A C C A T C C T A C C A A G C T A C C T T C C A T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T T C C A A C G T A G C A A G C T T G C T T C C T T G C T T C C T T G C T A C G A T G C A A G G T T G G T T G G T A G G A T C G A A C C T A G G T A G G A A C C A T C C T T C C T A C G T T C C T A G C T A G C T A G G A T G C A A C G T T C G A A G G T A G C T T C C T A G C T A C C A A G G A A G C T A C G A A G G A A C G A T C C A T G G T T G C T T C C A T C C A A G G A T C C A A C C A A G C T A G G T A C C A A C G T T G G T T C G A A C C T T C G T A G C T A G C T T G C T T G G A A C C A T C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C T A C G A T G G T A C C A A G C A A C C T A G C T A C C A A G C T A C G T AUB_9073 # subpop. label: 2 (internally 2) -2 2 1 1 2 1 2 2 2 1 1 1 1 2 2 2 2 1 1 2 2 1 1 2 2 2 1 2 2 2 2 2 1 1 2 1 2 1 1 1 1 2 2 2 1 2 1 1 1 2 1 2 1 2 1 1 1 2 1 2 1 2 1 2 2 1 2 1 2 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T A C C T T C C T T G C A T G G T T C G A T C C A T C G T T G C T T G C T A G C T T G G T A C C T A G G T A G C A T G C T T C G T T G C T A G C T T C G T A G C T T G C T A C C A T C C T A G C T T C C A A C C T T C G A T G G T A G C T A C G A A G C T T C G T A G C T A G C A A G C A T C G A A G G A T C C T A G C A A G G T T G G A A G C T A G C A A G G T T C C T A G G A A G G A T G C T A C G T A G G A T G G A A C G A A G G T A C C A A C C A T G G T A G G A T G C T T C C T T G C A A C G A T G C T A C G A A C G T A C C T A G C T A C C T A G G T A C C A A G C A T G C T A C C A A C G A A G C T T C C T A G C T T C C A A G G T A G G A A C G A A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G G A T G G A A G C A T C G T A G C T A G C A A G C T A C G A A C C T A C C A T G C T T G C A T G C A A C G T T G G A T C C A A G G T A G C T T G G T A G G T A C C T T G G T A G C T A G G A A C G T A G G A T C G A A G G T A G C A A G C T T C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A G G A A G G T T C C A A C G A A C C A A G G T A G C A A C G A T G C T A G C A T G G T T C C T A C C T A G G A T C G A A C C A A G G A T C G A T C C T A G C T A G G T A C G T T C C T T C C T A G C A T C C T A C C A T C C T T G G T T G G T T G C A A G C A A C C A T C G A A C G A T C C A T C C A A G C A A C C A A G C A T G C T T C G T T G C T A C G A T C C A T C G A T G G A T G G A A C C A A C C T A G G T A G C A T C C T A C C T T C C T A G G T A C G T T C C A A C C A T C C T A G C T A C G A T C G T A G C A A C C A T G G T A C C A A G G T A G G T A G G T A G C A A G C T A C G A A G G A A C G T A C G T T G C T T G C A A C C T A C G A T G G T T C C T A G C A A C G T T C C A A C G T T G C T T C G A A C C A T G G A A G G T T G G T A C C A A C C T A C C T A C G A A C G A T G G T T G C A T C G T T G G A A G G A A G C A T C C T A G G A A C G A T G C T T G C A A C G T A C C A T G G T A G G A A G G A A C G T A C G T A G C T A G C T A C G T T C C T A G C T T C G T A C C A A G C T T G C T T G C A A G G A A C C T A C G A T C G T T C G A T G G A A G G A A C C A A G G T T G C T T G C A A G C A T G C A A G G T T G C A T C G A A G G A A G C T T G G A A C C A T C G T A C C T T C C T T C C T A G G T A G C A A G C T A G G T T G G A T G C A T C G T A G G A A G C T A G C T T C C T T G G A A C C T T G C A A G C T A G C A T C G A A C G A T C C A T C G T T G C T T C C T A C C A A G C A T C C A T C G A T C C T A G G T T C G T A G G A A G G A T C C T A C G A A G C T T G G T T C C A T G C T T G G A A G G A A C C A T G C A A C G A A G G T T G C A A C G T T G C T A G G T T G C T T C C A A G C T A C G A T G G T A C C A A G C A A C C A A G C T A C C A A G G T A C C T +A C G A A C G T A C C A T G C A A C C T A C G A T G G T A G C A T C C A A C G A T G C T T G G A T G G T T C G A T G C A T G G T A G C A A C C T T G G T A C C T T G C T A G C A T C G A A G G T T G C A T G G T A G C A T C C T A C C T A C G T A G C A T C G T A C C A T G C T A G C T T C G T T G C T T C C A A C C A T C C T A G C A T G G A T G C T T C G A T C G T A G G A A C C A A G C T A C G T T G G A A G G A A G C A A G G T T G C T A C C T T C G A A G G T T G C T A G C T A G C T A G G T T G C T A G C A A G G T T G G A A C G A T C C T A G G A A C G T A G C T T G C A T G G A A G G T A G G A T G C T T C G A A G G A A C C A T C C A T C C A A G G T A G G T A G C A T C C A A G G T A C C A A C G T A G C T A G G T A C G T T G C A T C G T A C C A A G C A A G G T A G G A T G G T T G G T T C G A A G C T T G C A T G C A A G C A T C G T A G C A A G G A A G C A A G G A A G G T T G G A A C C A T C C T A G G A A C C A A C G A T G C A T G C T A C C A T G G T A C C T T C C A T C C T A G C A T C C T T G G T A G G T A C C T T G G T T G C T A G C T T G C A A C G A T G G A A G G T A C C A T C G T T C G A T G G T A C G T T C G T T C G T T G C A A C G T T G G A T C C T T G G T T C C T T C G T A C C A A G C A T G C A A G C A T G C A A G C T A G C A A C G A T G C T T G C A T C G T T C C T A C G T A G G A T G C T A C G T T G G A T C C A T C C T A G G A A G G T A C G T A C G T T G G T A G C A T G G T A C C A T C C A T C C T T G G T A G G T T G C A A C C A T C G A T C G A T G C A T G C A T C C A A G C A A G C A T G C T T C G A T C C T T C C T T C G A T C C A T C C A T G G A A G C T T C C T T G G T T G C A T C C T A C C T T C C T A G G T A C G T T C C A A C C A T C C T A G G T A G C T A G C A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T C G A A G C T T G G T A C C A T G C T T C G A T G C T T G C A T G G A T C G A A G G A T C C T A G G T T G C A A C C A T C G A A C C A T G G A A G G T T G G T A C C A A C C T A C C T A C G A T G G A T G G T A G C A T C G T T G C A T C C T T C G T A G C T A C G A A C C T T G C T T G C A A C G T T G C T A C C T A C G T A G G A A C G A T C C T A C C T A G C A T C C T T C C A T G C A A G C A T G C A A C C T A C G T T G C T T C G T T G G T A C C A T C C T T C G A A G C A A G C T A G C T A C G T T C C T T G G A A C C A A G C A A G G T T C G A T G G T A G G A A G C T T G G A A C C A A C G A A C G T T G C T T C C T A C G T T C G A A G C A T C C T A G G A T G C A T G C T T C C A A C C T T C G T T C C T T C C T A C G A T G C T A G C T T G C A A G C A A C C T T G C A T G G T T G C T T C G T A C C T A G G A T C C A T C G A T C C T A G G A T G C T A G C A T G G A T C C T A C G T T C G T A G G T A C G T A G C A T C C A A G C A A C G T A G G A A G C A A G C T T G G T T C G A A C C T A G G T T C C T T C C T A G C A A C G A A G C A A G C A A G C A A G C T A G G T A G G T A G C A A C G T AUB_9079 # subpop. label: 2 (internally 2) -2 1 1 2 1 2 1 1 1 1 1 1 1 2 2 2 2 1 1 2 2 2 1 1 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 1 1 2 2 2 1 2 2 1 2 2 1 2 1 1 1 1 1 1 1 2 2 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 2 1 2 2 1 2 1 2 1 1 2 1 1 2 1 1 2 1 1 2 1 2 2 2 1 2 1 2 2 1 2 1 1 1 2 1 2 1 1 1 2 2 2 1 1 2 1 1 1 2 2 2 1 1 2 1 1 2 2 1 2 2 2 2 1 1 2 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 2 1 2 2 1 1 1 1 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 1 2 2 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G G T T C C A A C G A A G C T A C C T A C G T A G C A A C G A A C G A A G G A A C G T A C G T T G C T T G C A A C C T A C G A T G G T T C C A A G G A T C C T T C C T T G C A T C C T T C G A A C C A T G C T A C C T A G G T A C C T A G C T A C C T A C G A T G C T T G G T A G C A T C G T T G G A T C C T T G C A A C G T A G G A A C G A T G C T A C G A T G G A T G C A T G G T A G G A A G G T A C G A T C C T A G G T A G G A T G G T A C C T T G C A T G G T A C C A A C C T T G C T A G C T T C G T T G G T T C C T T C G A T C G T T G C A A G G A A C C T A G C T T G G T A G C A A C C A T G C A T G C A A G G T T G G A A C C A T G C T T G G A T C G T T C G T A C C T T G C T T C C T A G C A T G C T A G C T T G C T T C G A T G C T T G C T A C G T T G G T T C G T T G G A T C C T T C G A T C G T A G C T T G C A A G G A A G C T T G C A T G G T T C C A A G C A A C C T A C C A T G C A T G G A A G C A T C G T T G C T A G G A T C G T T C C T A C C T T C C A A G G T A G C T T G C T T G G A A G G T T C C T A 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C C T A G G T T G C A A C C A T C G A A C C A T G G T A C G T T G G T A C G T A G G T A C C T A G C A T G C A A C G T A G G T A C C T T G G A T C G A A C C A T C C T A C G A A G C T T G C T A G C A T G G T T G C A T C C A T G C A A G G T A C G A T C C T A G C T A C C T A C G A T C C A A G C T T C G T A C C A A C C T A C G T T G C A T G G A T C C T A G C A T C C T T C G A A G G A T G G A A C C A A G C T T G C T T G C T A C C A A C G A A G G T T G G A T G G T A G G A A C C T A C G A T C G T T C G A A C C A T C C T T G C A A C G T T C G A A G C T A C G T T G G A T G C A A G C T A G G A A C C T T C G T T G G A T C C T T G C T T C G A A G C T T G C A T C G A A G C T A C C T T C G A A G C T A C C A A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C G A A C G A A G C T T G G T A C C T A G C A T G G A A G G A T G G T A G C A A G C A A G G T T G C T T C G T T C C T A G C T T C C T T C C T A G G A A C G T A G G T T C C A A G C A A C C T A G G T A G G A A G G T A C C T 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G T A G C A A C G A T G C A A G G T A G C A T G G A A C G A T C G A A G C T T C G T A G G A A C C A T C C T T C C T A G G T T G G A A G C T A G C T T G G A T G C A T G C A T C G T A C C A T C G T T G G A A C C A A C C T A G G T A G G A T G C A A G C T T C G A T C C A T C G T T G C T T C C T A C C T A C G A T C C A T C G A A G C T A G G T A C C A T C G A T G G A T C C T A C C T A G C A A G G T A G C T T G C A T G G A A G C A T C C A T C C T A C C A A G C T T G G T T C G A A C C T A G C T T G C T T C C T A G C A A C G T A G C A A C C T A G C A A C G T A G C A T G C A A C C A A C G T +A G C T A C G T A C G T A G G A T G G A T G C T A G G T A G G T A C C A A G G T T C C T T G C A A G G A A G G A T G G T A G G T A G C A T G G T T C C T T G C A T G G A T C C A T G G A A G G T T G C T T C G T A C C T T C C A T C G T A G G A A G C A T G C T T C G T T C C T T G C T T C G A A G G A T G C A T C C A T C C A A G C A T C C A A C C T T C C A A G G T T G C T A C C A A G C T A C G T T G G T A G C A A G C A A G G T T G C T A C C A A G G A A C G A T G C A A G C T A G C T A G G T T C C T A C C T A G G T T G G A A C C A A G C T A C G A A G G T A G G T T G C A A C G A A G C T A G G A T G C A A C C A T G C A T C C A T C C A A C C A A G G A A G G A A G C A A C C A A G G T A G G T A G C A T C C T A C G A T C G A T G C A A C G T A G C T T C G T T C G A T G G A A C C T T C G A T C G T T G C T T G C A T G C A A G C T T C C T A G C A A G G A A G G A T G G A T G C A T C G A A C C T A C G T A G G T A C C A A G C T A G G A T G C T A C C A T G C A A C G T T G G A T C C A T G C A T G C A T C G A A C C T T G C T T C C A A C G T T C G A A C C A A C C A T G G T A G G A T G G A A G G T A C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T T C C A T C C T T G G T A C C A A G G T T C C A A C G A A C C A A G C T A G G T T C G A T G C T A G C A A G G T T C C T A C G T A G G A T G G A T C G T A G C T T G G A T C C T A C C T A G G T A C C T A G C T T G G T A G C A A G C T A C C A A G C A T G G T T G G T T G G A T C C A A C C A T C G A T C G A T G C A T G C A A C C A A C G T T G C T T G G T T C G A T C G T T G G T A C G A T G G A A C C T A G C A T G G T A C C T T G G T T C G A T C G T A C C T T C C T A G G T A C G T T C C A A C C A T C C T A G C T A C G A T C G T A G C A T G C A T G C A A C G T A G G T T C C T A C G T A G C A T G C T A C C T T C C T A G C T A C G A A G C T T G C A A C C T A G G T A C G A T G C T A C G A A C C T A G G A T C G T T G C T T C G A A C C A T G G A A G G T A G G A A C G A T G G T A C C T T G C A T G G A T C G T A G G A T G C T T G G A T C C T T C G T A C G T A G G A A C C T A G C T A C C A A C G T A C C T A G G T A G G A A G C T A C G T A C C T A G C T T G C A A C C T T C C A T G C T T C G T A C C A A C C T T G G T A G C T T C G T T G C T A C C A T C G T T C G A A G C A A G C T T C G A A G C A A C G T A G C T A C C A T G C A T G C T T G G A T G G T A G G A T C G A A G C A T G G A A G G A A C G A T C C T T C G T A G G T T C G T A C C A A G G T T G C A T C C A T G C T T C C A A G C T T C G T T G G A A C C A A G C T A G C T A C C T A G C A A G G A T C G A T C C A T C G T T C C T T C C T A C C A A G C A T C C A T C G A T C C T A G G T T C G A A C G A A G G A T C G A A C G A A G C T T G G T T C C T T G C T T C C A T G C T A C G T A G G A A C C A T C G T T G G T A C G A A C C T A G G T T C C T T C C T A G C T A C C T A G C A A C C T A G C A A C C T A G G T A G C A T G C T A G G T AUB_9208 # subpop. label: 2 (internally 2) -2 2 2 2 2 1 2 2 2 1 1 1 1 2 2 2 2 1 1 2 2 1 2 2 2 2 1 2 1 1 1 1 2 2 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 2 1 2 1 2 1 2 2 2 2 1 2 1 2 1 1 2 2 2 1 2 2 2 1 2 1 2 2 1 2 1 1 2 1 1 2 1 1 1 2 2 2 2 1 1 2 2 2 1 2 1 1 1 2 1 2 1 1 2 2 1 1 2 2 1 2 1 1 2 2 2 1 1 1 2 1 1 1 1 2 1 2 2 2 1 2 2 2 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 1 1 1 1 1 1 1 2 2 2 2 2 2 1 1 1 1 2 1 1 1 2 2 2 2 2 2 2 1 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 2 2 2 1 1 1 2 1 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 2 1 2 2 2 1 2 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T G G T A C C A A G G A A G C A A G G A A G C T A G G A A C C T T C G A A G C T A C G A A G C A A G C A A G C T T C C A A C C A A C G T T G G A T C C T A G G T A G C T T G G A A G G T A C C T T G G T A G C T A G G A A G G A A C C A T G G A T C G T T G G A A G C T A C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T T C C A T C C T T G G T A C C A A G G T T C C A A C G A A C C A A G C T A G G T T C G A T G C T T G C A A G G T A G C T A C G A A G G T A G C T T G G T A G C A T C G A A C C T A G C T A G C A T G C T T C C T T G C A T G C A T C C T A C G A T C G T T G G A T G C T A C G A A G C T A G C A T C G A T G C T T G C T T G C A A C C A A G G T T G C T T G C T T C G T T G C T A C G A T C G A T C G A T G G A T G G A A G C T T C C T T G G T A G C A A C C T A C C T T G G T T G C T A G C A T G C T T C C A T G C T A C G T A C G A T C G A A G C T T G G T T C C A T C C A T C G A T C C T A G G T A G C A A C G T A C G A A G G A A G C T A C G A A G C T T G C A A C C T A G G T A C G A T C G A A G G A T C C T T C C A A C G T T C C T T C G A A C G T A G G T A C C T T G G T A C G T A G G T A C C T T C G A T G G A T G G T A G G A T C G T A C G A T C C T T C G A T C C T A G G A A G G A T G C T T G C A A C G T T G C T A G G T A G G A A G G T A C G A A C C T A G G T A G G A T C C T A C C A T G C A T G C A T C C A A C C T A C G T T G C A T G G A A C C T T C G A A C C T A C G A T G C A A G C T A C G T A G C T A C C T T G C A A C C A T C G T T C C T T G G T T G G T A G G A A C G A A C C T T G G A A G C A A G G A T G C T T C C T A C G T T G C T A G C T A G G T T C G T T G C A A C G T A G G A A C C A A C G T T C C T A G C T T G C A A G C T A G C T T G C A A G C A A C C T T G C A T G G T T C C T A G C A T C C T A C C A T G G A T C G A T C C T A G G A T G C A A G C A T G G A T C C T A C G A A G C T T C C T A C G A T G C A T G G A A C C A T C C T A G C A A C G A A G C T T G G A T G G T T C C A A G C T T G C T T C C T T G G A A C G A T G C T A G C A A G C A A G C T A G G T A G G A T G C T A G G T +A G G T A C C T A C G A T G C A T G G T T G C T A G G A A G C A T C C A A C G A T G C T T G C A A G G A T C G A T G G T A G G T A G C A A C C T T G G T T G C T T G C T A G C A T G C T T G G A A C G T T G C T A C C A T C C A A C C T A C G T A G G A T G C T T C C A T G C A A G C T T C C T A G C T T G C A T G C A T C C T A G C A T C C A T C C A T C G A A C G A T G G A A G G A A C C T T C G T A G C T A G G A A C C A A G G T A G C T A C G T A G C A A C G T T G G T T G C T T G C T A G G T T G C T A G C T T G G T T G C T T C G T A G C T A C G T A C G A A G G T T C C A T G G A T G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A T G C T T C G A A G G T A G C A A C G T A G C A A C C A T G G A T G C A T C C T A G C T T C G T A G C T T C G A A G G T T C G T T G G T A G C T A G C A T G G T A G G T T C G T A G C A A G G A A C C A A G G A A G C A T C G A A C C T A C C T A G C T A G G A A G C A A G G A T C G A A C C A T G C A T C G A A G G A T G C A T G G T T C C T T G G A A G G T A C G T T G C T A G C T A G G A A C G T A C C A T G G A A G G T A G C A T C G T A G C A A G G T T C C T T G C T A C C T T G C A A G G T A C C T T G C T T C C T T C G T T G G T A C C A A G G T A G C A T C C A T C C T A G C T A G C A A G G T T C C T A G G A T G G T A C C T A C G T A G C A A C C T T G G T T G C A T C G A T C C T A C C T A G G T A C G T A C G A A G G T T G C A T G C T A C G A T C C A T G G T T G G T T G G A A G C A A C C A T C G A A G C T A G C A T C C A A C C A A G C T T G C T T G C T T C G T T C G T A C G A A C G T T G C A A G C A T G G A T C C A A G C A A G C T A C C A A C C T A C C T T G G A A G G T A C C A T C C A A C C A T C C T A C G A T G G A T C G T T G G A T G C T T G G A T G G A A G G T T C C T A C G T T C C A A G C T T G G A A C G A A G C T A C C T T G C T T G C A A C C T A C G A A G G T T G C A A C G A T C C T T C C A A C G T T G C A T G C T T C C A T G G A A G G T A G G A T G C A A C C T A C C T A C G A T G G A A C G T A G G T A G C A T G G A A G G A T G C A T C C T A C G A A G C T T G C T T G C A A C G T T G C T A C C T T G C T T C G A A C G T A C G T T G C T T G C A T C C T T C C A T G C A T G G T T G C A A C C T T G C T A G C A T C G T T G G T T C C A A C C T A G C T T G C A A G G A A C C A A G C T T G G T A G C A A C C A T G C A T G C A A G G T T G G T A G G A T C G A A G C T T C G A T C G T A C G A T C C T T C G T A C G T T C G A A G C A T G C A T G G A T G C A A G C A T C C T T G C T T C G T T C C T A C C T T G C T A G C A A G C T A G C A A G G A A G C T T C G T T C G T T G C T T C G A A C C T A C G T T G C A T C C A A G C T A G G A T G C T A G G T A G G T T C C T A C G A A G G T T G C T A G C A T G C A T G G A A C C A T C C A T C C A A G C A A G G T T G G T T C G A A C C T A G C T T G C T T C C A A G C T A C G T A G C T T C C A A G C A A C G T A G C A T G C A A G G T A C C T AUB_9211 # subpop. label: 2 (internally 2) -2 2 2 2 2 1 2 2 2 1 1 1 1 2 2 1 1 2 1 2 1 2 2 2 2 2 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 2 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2 2 2 1 2 1 2 2 2 2 1 2 2 2 1 1 2 2 1 2 2 1 2 2 +T G C A A C G T A C C T T C C T A C C T A G C T T G G T T C G T T C C A A C G A A G G A T G C A A C G A T G G A T G G T A C C T T G C T T C C T A C C T T G C T T G G T T C C A T C G A T G G T T C C T T G G T A G C A A C G T A C C T A C G T A G C A T G C T A C G T T G C A A C C T A C C T A G C T T C C A A C C A T C C T A G C T T C C A A C G T T C C A T G G A T G G A A G C A A G C T A C G T T G C A A G C A A G C A A G G T T G C T A C C T A G C A T C G A T C C A A G C T A G C A A G G T T C C T A G C T T G G A A C G A A C G T T G G A T G G T A C G A A G C T T C C A A C G A A G G A A G G A T G G A T G G T T G G T A C G A T G C T A C G A A C G A A C C A A G C T A C G A A G G T A C C A A C C A T G C T A C C A A C G A A G C T T C C T A G C T T C G T A C G T A C C T T G G T T G G T T C G A A G C T T G C A T G C A A G C A T C G T T C G A T G G A A G G A T G G A A G G T A G G T A G C T A C C T A G G A A C G A A G C T A C C A T C G T T C C A T G G T 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C A A C C T A G C T A G G A A C G A A G C T T C C T A C G T T G G T T G G A T G C T A G C A T G C A T C C A T G C A A C C T A G C T A C G T A G C T T G C T A C C T A G G T A C G T T G G A A G G T A C G A T C G T A C G T A C C A A G C T A C G T A C C A A G G T T G G A T C G T A G C T T G C A T G G T T C G T T C G T T C G A A G G A A G G A T C C T T C G T A G G A A C C T A G C A A G C T A C G A A G C A A G G A T C G T T C C A A C C A A C G T T G G A T G C A A G C T A G C A A C G A A G G T A G C A T G G T T G C T T G C T A G C A A C C A T G G A T C C T T G G T A G C T A C G A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A T G G A A C C A A G G T A G C A A C G A T G C T A G C A T G G T T C C T A C G T A G G A T C G A A C G A T G C T T C G A T C C T T C G T A G G T A C G T A C G A A G G T T G C A T G G T A G C A T C C T T C C A A G G T A G G T T G C A A G C A T G G A T C G A T G C A T C C A A C C A A G C T T C C T T G C T T C G T T C G T T C C T T C G A T C C A T C C A T G G A A G C T T C C T T G G T T G C A T C C T A C C A T C G T A G G T A C C T T C C A A G C T A G C A A G C T A C C T T C G T A G C A A G G T T C C A A C G A T G G T A G C T A C G T A G C A A C G T A C G A A G G A A G C T A C G A A G C T T G C A A C C T A C G A T G G T T C C T A C G A A C C T T C C A A C G T A C C A T G C T T C C T A G G T A C C T T G G A A C G A A G G T T C C T A C G T A C G A T G G T A G G T A G C A T G G A T C C T T C G A A G C A T G G A A C G A T G C T T G C T A C G T T G C T A G G T A G G A T G G A A C G T A C G T A G C T A G C T A C G T T C C T A G C T T C G T A C C A A C C A T G C T T G C A A G G T T C G T A C C A T C C A T C G A T G C A A G G A A C C T A G C T T G G T A G C A T C G T T G C A T G G T T G G A T G G T A C G A T G C T T G G A T C C A T G G A T G G T T C C T T C G T A C G T A G C T A C C T T G C T A G G A T G C T T G C A T C C A A G G A A G C T T C C T A G C T T G C A T G C T A G C T T G C A A G G A A C C T A C C A T G G T T G C T T C G A A C C T A G C A T C C A T C G A T G C T A G G A T G C T A G G A A G G T T C C T A C C A A G C T A G G T A G C T T G C T T G G A A G C T A C C T A G C T A C C A T C G T T G C T T C C T T G C T A G C T T G C T T C C T A G G A A C G A T G C T A G C A A G C A A C G T A G C A T G C A A G G T A C C T +A C C T A C G T A C G T A G C T A C C T A G C T T G G T A C C T T C C A A G G T T C C T T G C A A G G T T C G A T C C T A C C T A C C A T G G T T G C T A G C T T G G T T C C A A C C A T G G T T C C T T G C T T C C A T C C T A C C T A G C A A C C A T G C T T C G A T C C T T G C T T C G A A G G A T G C A A C C A T C C T A G C T T C C A A C C T T C G A A G G T T G C T A C C A A C C T T C G T A G G A A G G A A G C T A G G T T G C T A C C T T C G A A C G T T G C A A G C T A G C A A G G T T G C T A G C T T G G T T G G A A C G A T C C A T G G A A C G A A G G T T G C A T G G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A T G C T A C C A A G G T A G G T A G G T A G C A A C C A T G G A T G C A T C C T A G C A A G C A A G G T A G G A A C G T T C G T A C G T T C C T T G C A T G G T A C C T T C C T A G C A A G G A A G C A A G G A A G G T T G G A A C C A T C G T T C G T A C C A A C G T A C C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C T T G G T A C G T T G G T A C G T T G C A A C G T A C C A A G G A A G G A T G G A T C G T A G C A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C A T G G T A G C T T C C A A G C T T C C A T G G T T C C A A C G T A G G T T C G A T G C A A C C A A G G T T G G A A C C T A G G A T C C A A C C A T G C T T G G A T G C T T G G A A G G A A C C T A G G T T G G T A G C A T G G T A C G A T C C A T C C T T G G T A G G T T G C A A C C A T C G A T C G A T C C A T C C A A G C A A C C T A G G T A G C T T C G T T G C T T C C T T C G A T C C A T C C A T G G A A G G T A C C T T G C T A G C A T C C T A C C T T C C T A G G T A C G T T C C A A C C A T C C T A G C T A C G A T C G T A G C T T G G T T C C A A C G A A G C A T C C T T G G T A C C A A G C T T C G A A G G A A G G T A C G T T G C T A G C A A C C T A C G A T C G T T C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G T A G G A A C C A A C C T A C C T A C G A T G G A T G G T A G C A T C G T T G G A A G G A T C G A T C C T A C G A A G C T T G C T A G C A A C G T A C C A T G G T A C G T A G G A A C G T A C C T T G C A T G G A T G G T T C C A T G C A T C C T A C C A A C C T T G C T A G C A T G G T T G G T T C G A T C C A T G C T T C C A A G G A A C C A A G C T T G G T A G C A T C C T T G C A A G G T T G G T T G G T A G G A A G C A A G C T T C G T T C G T T C C T T C C T T C C T A C G T T G C A A G C T A G G T T G C T A G G A A G C T A C G T T G G T T C G A A C C T A G G T T G G T T G C A A G C T A G C A A G G A T C G A T C C A T C G T T G C T T C C T A C C A A G G A T C C A T C G A A G C T A G G T T C C A T G G A T G G A T G G A A C G A A G G A A C C T A G C T T G C T T G G A A C C A T C C A T C C A A G C A A G C T A G C A A C G T T G C T A G G T T G G T T G C T A G C A T C G T A G G T A C C A A G C A A C G T A G C A T G C A A C C A A C G T AUB_9215 # subpop. label: 2 (internally 2) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 1 2 2 2 2 2 2 1 1 2 2 1 1 1 1 1 2 2 2 2 1 1 1 2 2 2 1 2 2 1 2 2 1 2 1 1 1 1 1 2 1 2 1 2 1 2 2 1 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 1 2 1 1 2 1 2 2 2 1 1 2 1 1 1 2 1 2 1 2 2 2 1 1 2 2 2 1 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 2 1 2 2 1 1 1 1 1 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 1 1 2 1 2 1 2 2 2 2 1 2 1 1 1 1 2 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 2 1 2 1 2 2 2 2 2 2 2 1 2 1 1 1 2 2 2 1 1 1 2 2 2 2 1 2 1 1 1 2 1 1 1 2 2 1 2 1 1 2 1 1 2 1 1 2 2 1 2 1 2 1 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 1 2 2 2 1 2 2 1 2 2 2 2 1 2 2 1 1 2 1 2 1 1 1 1 2 2 2 2 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 2 1 2 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T G C T T G C A A G G T T C G A T G G T T G G T A C C T A C C T T G G A A C C T T G C T A G C A T C G A T G G A A C G T T G C T T C C A T C C A A C C T A C G T A G G A T G C T T C G A T G C A A G C A T C C T A G C T T G C T A C C A T C C T A G C T T C C A A C C T T C G A T G C A A G C T A C C A A G C T A C G T T G G T A G C A A C G A T G G T T G C T A C C T A G G A A C G A T G C A A G C A A C G T A G G T T G C T A G C T T G G A T G C T T C G T A G C A A C G A A C G A A G G T T C C A T G G A A G G T T G G A T G C A A C C T T G C A A C G A T G C T A C C T A G G A A G G T T G C T A C G A A G G T A G G T A G G T A C C T A G G T A C G T T G G A T C C T A G C T T C G A A G G T A G G T T G G T T C G T A C G A A G C T T G C A T G G T A G C T T C G T A C C A A G G A A G G A T G G T T G G A T C G A A C C T A C C T A G G A A C G A A G C T A C C A T C G T A C C A T G C T A C G T T G G A T C C A T G C A T C C T T G C A T G G T A C C T T G G T T G C T A G C A T G C T T C C A T G G A A G G A T G G A T C G T A C C A T C C T A C G T T G C T A C G T T G C T A G G T A G G T T C C T T G G A T C C T T G C T A C C A T G G A T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A T G G T T G G A A C C T A G G A A G G A A C G A A G G A T C G A T G C T A G G A A G G T A C G T A G C A A G C T A C C A T G G T A G C A T C C T T C C T T G G T A G G T T G C A A C C A T C G A A C G A T G C A T C C A A C C A A C C A A G C A T G C T T C G A T C C T T C C T T C G A T C C A T C C T A G C A A C C A A C C T T C G T A G C A T C C T A C C T A G G T T G C T A G G T T G G T A G C T A G C A A C C T A C C A T C G A A G C A T G G T T C C A A C G A A G G T T C C T A C G T A G C A A C G T A C G A A G G A A G C T A C G T T G C T T G C A A C C T A C G A A G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G T A C G T A G G T A C C A A C C T A C C T A C G A T G G A T C G T A G G T A C C T T G G A A G G A A C G A T C C T A C G T A G C T T G C T A G C A A C G T T G C T A C C T A G C T T G G T A C G A A C C T A C G T A G C T T C C T T C C A T G C A T C G T A C C T T G C T A C C T T G C A T C G A T C C T T C C A T C C T T C G A A G C A A G G A A C C A T G C A A C C T A G C A T C G T T G C A A G G T T G G A T G G A A G G A A C G A T C G A T G G A T C G T A C C A T C C T T G C A A C G T T C C A A G C T T G C T T G G A T G C A A G C T T C G A A G C T A G C T T C C T A G C T A C C A T G C A A G C T A G C A T C G A A G C T A C C T T C G A A G C T A C G A A C C A A G G A T G C A T C G A T C C T A G G T A C C A T C G T T G G T T C C T A C G A A G G T A G G T A G C T T G C T T G G A A G C A T C C T T C C T A C C A A G C T T G G T T C G A A C C T A G C T T G C T T C C T A G C A A C C T A G C A A G C T A G G T A C C T T G C T A C C T A G G T A C C T +A G C T A C C T A C G A T G C T A C G T A G G A T G G T A C G T T C C A A G G A T G C T A G C T T G C T T G G A T G C T A C C A T G C A A C C T A G C T A G C A T C G T T G C A T C G A A C G T T G C A T G G T A G C A A C G T A C G T A C G T T G C A T G G A T C G A T C C T T C C T T C C T T G C T T G C T T G C A T C C T A G C A A G G A A C C T T C C A T G G T A G C T T G C A A G G T T C G T T G C A A G C A A G C A T G G T T G C T A C C T A G G A A C G A T G C A A G C T A G C T A C G A T C C T A C C T A G G T A G G T A C C T T C C A A G G A A C G A A G C A T C C A A C G A A C G T A G G T T G C A A G C T T G C A A C G A T G C A T C C A A G G T A G G T A G C T A C C T A G G T A C C A A G C A A C C T A C G A T C G A T G C T A C G T A G G A A G C A A G G T A G G A A C G A A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G G A T G G A A G C A T C G A A C C T A C C A A G C T A C G A A G C T A G C A T G G T A C C A A C C A A C G T T G G A T C C A T G C A T G C A T C C A A G G T A C C T T G G T A C G T A G C T T G C A T G C A T G G A T C C A T G G A T C G T A C G A T G G T A C C T T G G A T C G T T G C A A G G T T G G A T C C T T G G T T C G A A G C T A C C A A G C A T G C A A G C A T G C A A G C T A G C A A G G T T C C T T C C A A G G T A G G A A C G A A G G T A G C T T C G A T G C T T G G A T C C T A C C T A G G T T C C T T G C A T G C A A G C A T C G T A G C A T C C T T C C T T G G T T G C A A G C T A C C A T G G A A C G A T G C A T G C A A C C T A C C A A G C A T G C A A G G T A G C A A G G T A C G A T C G A T G G A T G G A A G C T T C C T T G G T T G C A T C C T A C C T T C C T A G G T A C G T T C C A A C C A T C C T A C C T T G C A T G G A A G C A T G G T T C C A T C G A A G C A T C C T A C G T A G C A A G C T A C C T T C C T A G C T A C G A T G C T T C G T A C C T A C G A T G G T T C C T A C G A A C C T T C C A A C G T A C C A T G C T T C C A T G G T A C G A T G G T A C G A A G G T T C G T A G C A T G C A T G G T T G C A T C C T T G G A T C C A T C G A A C C A T G G A A G C T T G C T A G C A A C G T T G C T A G G T A G G A A G G T A C G A T C G T A C G T A C C T A C G A A G C T T G C A T C C T A C C A A C C T T G C T T G C A T G G A A G G T T C C A A C G T T C G T T G G A A G C T A C G T A G G T T G G T A G C A T C C A A C G T T C C T T G G T T G G A A C C A A G C A T C G A T G G A A C G T A C C T T G C T T G C A A G G T A G C A T G C T T C C T T G G A T G G A A G C A A C G T T G C T A G C T T C C T A G C A A C C T A G G A A G C T A G G A T C G A A G C T T C C T T C G T T G C T A C G A A C C A A G C A T C C A T C G A T G C A T C C A T G C A T C G A A G G T T C C T A C G A A G G A A C C T A G C T A G C A T G G A T G C T A C G T A G G A A C C A T C C T T G G T T C G A A C C T A G C T T G C T T G C T T G G A A C G T A G C T T G C A A G G A A G C T T G G T A G G T A G C A A C G T AUB_9230 # subpop. label: 2 (internally 2) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 1 1 2 1 1 1 2 2 2 2 2 2 2 2 2 2 2 1 1 2 1 2 2 1 2 1 2 1 1 1 2 2 2 2 1 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 2 1 2 1 2 2 1 2 2 1 2 1 2 1 1 2 2 2 1 2 1 1 2 1 1 2 1 2 2 1 2 2 1 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 2 1 2 2 1 2 2 1 1 2 1 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C T T G C A A C C T A C G A T G G T T C C T A G C A A C G T T C C A A C G T T G C T T C G A A C C A T G G A A G G T A G G T A C C A A C C T A C C T A C G A T G G A T C G T A G G T A G C A A C G A T C G A T C G A T C C T A G G A A G C T T G C T T G G A A G C A A C C T A G G T T G G T T G G T A C G A A C C T A G G T A G C T A C G T T C C T A G C T T C G T A C C A A C C T A C G T T G C A A G G A T G C T T C G A T C C T T C G A A G G A T G C T A C C A A G C T T G G T A G C A T C C A A C G T T C C T T G G T T G G A A C C A A G C T T G C T T C C A A G G A A C C T T G G T T G C A A C G T T C C A A G C T A C C T T C G T T C C A A G C T T C C A A G C T T C G A A C C T A G C T T G C A T G C T A G C T A G C A A G C A A G C T A C C T A C G A A G C T A C C T A C C T A G C A T C C A T C C A T C C T A G G T A C C A T C G A T G G A T C C T A C C T A G C A T G C T A G C A T C C T T G G A A G C A T C C A T C C T T C C A T C G T T G C T T G G T T G G A T G G T T C C T T C C T T G G A T C C T A G C A T C 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C A T C C A T G G A A G G A T C C A T C G A T C G T A C G A A G C A A G C T A G G T T G C T A C C T A G C A A G C T A C C T A G C T T G C T A G G T T G C T A G C T T C C A T G G A A C G T A G C T A C G A A G G A A G G T A C C A A C G A A G G T A G G A T G G T T G G T T G C A A C C A T G C T A C C A A G G T T C C T A G C A T C C A A G G T A G C A A C C T A G G A A C G A A C G T T C C A A C G T A C G T A C C T A C G T A G G A A G G T T G G A A C G T T C C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A T C G T A G G A A C C T A C C T A G G A A G G A A G C A A G C A T G G T A C C A T G C T A C G T A G C A T G C A A G C T A G C A T C C A A G G T A G C T T G G A A C G T A G G A A G G A A C G T T C G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A T G C T A C C A A G G A A G G T A G G T T C G T A G G A T G G A T G C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A C C T A G G T A C C T A C C A A G C T A C C T T G C A T G C A T C C T T G G A T G G T A G C A T G G T A C C A T C C A A G G T T G C A T C G A A G C A A G C A A G C T T G C T T C C A T C G A A C G A A C G A A G C A A G C A T G G A A G G T A C C A A G C T A C G A A C G T T C C T A C G A A G G T A C C T T G C T T C C T T C C T A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A T C C T A C G T T C G A A C G T A C G A T G C T T C G A A C C T A C G A A C G A A G C A A G C A A C C A A G G A T G C T T G C T T G C A T C C A T G G T T C G T A G G T T G C A A G C T T C C T T G G A T C C A T C G T A G C A T G C T T G G A A G C T T C G T A G C T A C G A A G G A T G C T A C C A A G C A A C C A T G G T A G C T A G G T A C G T T G G T A C C A T C C A T G G T T C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G A T G C T T C C A T C C T T C G A A G G A A G C T A C C A A G G T A C C T A G C A A C C A T C G T T C C T T G G A T G G T A G G A T C C T T G G A T G G A A G G A A G G A T C C T T G C A T G G T A C C T A G C A A G G T T C G T T G C A A C G T T C G T T G C T A C G T T C C T T G G T T G C T A G C T A G C A A C C A A G C A A G C T T C C A T C G T T G C A A G G T A C C A A C G A T C G A T C G A T G C A T C G T T G C A A G G A A G G A T C G T A C G A T G C T T G C T A C C A T G C T T G G A A G G A T C C T A G C A A C C T A C C T T G C T A C C T T G C A A G C T T G C T T G C T A G C A A C G T A G C T T C C T A C G A A C C T A G C T A G C A A G C T A C G T +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C C A A C C A A G G T T C C T T G C A T G G A A C G A A G C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A T C C A T G G T T C G A T G G T A G C A T C G T A C C T A G G A A C C A T G C T T C G A T G C A A G C T T C G T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C C A T C G A A G C T A C C A T C G A T C C T A G C A A C C A A G C A A G G T A G C T A G C T A C C A A C C T A C C T A G C T T G C T A G G T T G G T A C C T T C C A T G G T A C G T A G C T T G G A A C C A A G G T A C C T A C G T T G G T A G G T T G C T T G C T T G C A T C C A T G C A A C C A A G G A T C C T A G C A A C G A A G C T T G C A A C G T T C C A A C G T A C G A T G C A T C C T A G C T T C G A A G G T T G G A A C G T A C G T A G G A A G C T T G C T T G G T A G C A T G G A A C G A A G G A A C C A A G G A A G G T T C C A A C C T A C C T A G G A A G G A A G C A A G G A T C G A A C C A T G C T A C G T T G C A T G C T A G C T A G C T T C C A A G G T A C G A T G C A A C G T A G G A A G C T T G G T T C G T A G G T A C C A T C G T A G C A A G G T T C C T T G C T T C G T T G C A A G G A A G G T T G G A A G C T T C C T T G G T A C C A T G C T A G G A T G C A T C C T A G G A A G G T A G G T T C C T A G C A T C G T T G C T A C C T A G G A T G G T T C G A T G C T T G G A T C C T A G C T A G G T A G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G A A G G T A G G A T G C T A C C A T G G A A G G A A C C A T C C A A G C A A C C T T G G T A G C T T C C A T C C A T C G T A C G A A G C A A G C A T G G A A G G T A C C T T G C T A C G T A G G T A C G T A C C A A G G T A G C T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T G C T T G G A A C G A A G C T A C C T A C G T A C C A T C C T A G G T A C G A A G C T A C G T T G C T T C G A A G C T T C G A T G G A A G C A A C G A T C C T A G G A T G C T T G C T T G C A T C C A T G G T A G G T A G G T A G C A A G C T A C G T A C G A T C C A T C G T A C G A T G C T T G G A A G C T T C G T A C C T A G C T A G G A T G C T A C C T T G G T T G C A A G G T T G C T T G G T A C G T T C G A A G C T A C C A T G G A A C C T T G C A T G G T T G C A A C C T T G C T T G C A A G G A T G G T T C C A T C C A T C G A A G G A A G C T A C C A A C C A T G C T T G C A A C C A T G G T T C C T T G G A T G G T A C G A A C C A A C C T T G G T A G G A T G G T T C C T T G C A T C G T A C G T A G C T T G G T T C G T T C C A A G C A A C G T T G C T A C G T T C C T T G G T A G C T T G G T A G C T A C C A A G G A A G C T T G C A T G G A T G C A A C C A T C C A A C G A T C G A T C G A T G C A T C G T T C C T A G G A T G G T A G C T A C G A T G C T T G C T A C G A T G C T T G G A A C C A T C C T A C C A A C C A A C C T T G C T A C C T T G G A A G C T T G G A T G C T A G C A A C G T A G C T T C C T A C G A A C C T A G C T A G C A A G C T A C G T BAO_226 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 1 2 1 2 1 2 2 1 2 1 1 2 2 1 2 2 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 2 1 1 2 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 2 1 2 2 1 2 1 2 2 1 1 2 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 1 1 1 1 1 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 1 1 2 2 2 1 1 2 1 2 1 1 1 1 1 1 1 1 2 2 2 1 1 1 2 2 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 1 2 2 1 2 2 2 2 2 2 2 1 1 1 2 2 1 1 2 2 1 2 2 1 2 2 2 1 1 1 2 2 1 2 2 2 1 2 1 2 2 2 1 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2 2 1 1 2 2 2 2 2 2 1 2 1 1 2 2 2 1 1 1 1 2 1 2 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 2 1 2 2 2 2 1 2 +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G A A C C A A G G T T C C T T G C A T G G A A G G A A G C T A G G T A C C A T G C T T G C T T G C T T G G T A G C A A C C T T G G T A C G T T G G T A C C A T C G T A C C T A G G A T G G A T C G A A C G A T G C A A G C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C C T T C G T A G G A A C C A T C G A T C G T A G G A T G C T A C C A A G G T A G C T A G C T A C C A A G C T A C C T A G C T T G C T A G G T T G C T A G C T T G G T T G G T A C C T A G C T A C G A A G G A A G G T A C C T A C G A A G G T A G G T T G C T T G C T T G C A T C C A T G C A A C C A A G G A T C C T A G C T T C G A A C C T T G C A A C C T A C G A A C G A A C G A T G C A A C G T A C G T T C C T A C G T A G G A A G G T T G G A A C G T T C C T A G C A T G G T T G C A T G G A A C C A T G G A A G C A A G G A A G C T A G G A A C C T A G C T A G G A A G G A A G C A A C C A A G G T A C C A A C C A A C G A A G C A T G C A A G G T A G C A T C C A A G G T A G C A T G G T A C G T A G G A A G C T T G C T T G G T T C C T A C C A T C G T A C C A T G G T T C G T T G C T T C G T T G C A A G G A A G G T T G G A A G C T T C C T T G G T A C C A A G G A T G C A A G C T T C C A A C G A A G G T A G C T T C C T A G C A T C G T T G G A A C G A A C G T T G C T T G G A A G C T T G G A T C C T A C C T A G G T A C C T T G C T T C C T A C C A T G C T A G C A T C C T T G G A T G G T A G C A T G G A A C C A T G C A A G G A A C C A T C C A A G C A A C C T T G G T A G C T T C G A A C G A A C C T A C G T T C C T A G C A T G G T A G C A A G C T T G G T A C G A A G G T A C C T T G C T A G G T A G C A A C C A A G C T T C C A A G C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T T C C T A C G T A C C A T C C T A C G T T C G A T C G T A C C A T G C T T C G A T C C T T C G A A C G T T G C A A C G A T C C T T C C T T G C A A C C T A G C A T C C A T G G T A C G T A G G T T G C A A G C T T C C T A C G A T G G T T C G T A G C A T G C T T G G A A G C T T C G T A C C T A G C T A G G T A G C T A G G T T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C A A C C T A C C T A C C A A G C A A G C A A C C A A C C T T G C T T G C T A G G A T G C T A C C A T C C T T G G A T G C A A G C T A G G A A G C T T C C T T G C A A C C A A G C T T C C T A G G A A G C T T G C A A G G A T G G A T C G A A G G T A C G T T C C T T G C A T G G T A C G A A G C T A G G T T G G T T G C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G G A T G C A T C G T T G C A A G G A A C C T A G C A T C G A T C G A A G C A T C G A T C G T A G G A A G G A T C G A A C G A T G C T T G C A A C G A T G C T T G G A A G G A T C C T A G C T A C C A T C C T A C C T T C G T T G G A A G C T T G C T T C C T A G C A A C G T A G C A T C C A A G C A T C C T A G C T A G C A A G C T A C G T +T G C T T G G A T G C T A G C A A G G T T G C T A G G T A C G T A C G A A G G T T G C T T G C T T G G A A G G A T G C T A G G T A G C A T C C A A G C A A C C T T G G T T G C A A G C A T G G T A C G T T G C T A C C A T C C T A C G T A G G T T G C A A G C T A C G A T G C A A C C T T C C T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C C A T C G A A G G A T C G A T C G A T C G T A C G T A G C A A G C T A G G T T G C T A G G T A C G A A G C T A C C T A G C T T G C T A G G T T C C T A G C T T C C A T G C T A C G T A G C T T G G A A C G A A G G T T C C A A C G A A G G T A G G A T G G T T G G T T G C A T C C A T G C A A C C A A G G A T C C T A C C A T C C A A G G T A G G A A C C T A G G A A C G A A C G T T C C A A C G T A C G T A C G T A C G T A G G A A C G T T C G A A C G A A G C T T G C A T G G T T G C A T G G A A C G A A G G A A C C A A G G A A G G A T C C A A C C T A G C T A G G A A G G A A G C A A C C A T G G T A C C A T G C T A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T T G G T A C C T A G G T A G G A A G G T T C G A A G G T A C C A T C G T A C G A T G G T A C C T T G C A T C G T T G C A A G G A A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A A G C T A C C T A G C T A G G T A G G T T C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A G C T A G G T T G C T T C C A A G G T A C C A T G G T A G C A T C G T T C C A A G G T A G G A T G C A T C C A T C G A A G C T A C C A T C C A A G C A A C C T T C C T T G C T T C G T T C G A A C G A A C C A T C C A T G C T T G C A A G G T A C C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A A G G T T C C T A C C A A G C A A G C T A G G A A G G A A C G T A C G T T G C T T C G A T C C T T C G A A C G A A G C A T C G A A C C T T C C A A C G T A C C T T G C A T C C A T G G T A C G T A G G T T G C A A C C A A G C T T G G A T G G A T C G T A G G A T C G T T G G A T C C T T C G T A C C T A C G T A C G A T G C T A C G A A G C A A C C A T G G T A G C T A G G T A C G T A C C T T G C T A G C T T G C T A C C T A G C A T C C T A C C A A C C T A C G T T G C A A G G A T G C T T C C A T C C T T C G A T G C A A G C T A G C A A C C T T C C T T G G A A C C A T G C A T G C T T G G T T G C T T G C A A G G A A C C T T G G A A G G A T C G T T C G T T C G T A C G T A G C A A G C A A G C T T G G A T G C A A G C A A C G T A G C T T C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T C C T T G G T T G C A T C G A A C C A A C C A T C G A T C G A T G C A T C G T T G C A A G G A A G G A A C G T A C G A T G C T T G C T A C G A T G C T T G G A A G C T A C G T T C G A A C C A T C C A T G C T A C C T T G C A T G C T T G C A T G C T A G C A A C G T A G G A T C C A A G C A T C C T A G C A T G C A A C C T A G G T BAO_228 # subpop. label: 3 (internally 3) -1 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 2 1 2 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 1 2 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T G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A G G A A G G A A C G T A C G T T G C T T C G A A G C T A C G A A C G T T G C A A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T T C C T A G G A T G G A T C G T A G C A A G C A T C G A A C C T T C G T A C C T A G C T T G G A T G C T T G C T T G G T T G C A A G G T T G C T A G G T A C G T T G G A T G C T A G C T A G G A A C C T T G C A T G G T T G G T A C C T T G C T T G C T A G G A T G C T T C C A T C G T T C G A A G C A A G C T A G C T A G C T T G G T A G G A A C C A T G C A T G G T T G G T T G G T A G G A T G C T A C C T T C G A A G G A T G G T T C C T T C C T A G C T T G C T A G C A T G G T T G G T T C C A T G C A A C G T T G C T A C G T T C C T A G G T A C G T A G G A A G C T A C C A A G G A A G G A T G C A T C G T T G C A A G C T A C C T A G C A T C G A T C G A T G C A T C G T T G C T A G G T T G G A T C G A A C G A A G C T T C C T A C G A T G C T T G G A A G G A T C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G G T A G G A A C G T A C C T A G C T A G C A A G C T A C G T BAO_231 # subpop. label: 3 (internally 3) -2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 1 2 2 2 2 1 1 1 2 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 2 2 1 1 1 1 1 2 2 2 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 1 1 2 1 1 1 2 1 1 1 1 2 2 2 1 1 1 1 2 1 1 2 1 2 1 1 1 2 2 1 1 1 2 2 2 1 2 1 1 1 2 2 1 1 1 2 2 2 2 2 2 2 2 1 2 1 2 1 1 2 1 1 2 2 1 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 2 1 1 2 1 2 2 1 2 2 1 2 2 2 2 2 2 1 2 1 1 2 1 2 1 2 2 1 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 1 2 1 1 2 2 2 2 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 1 1 2 1 1 2 2 2 1 1 2 1 1 2 2 2 1 1 2 1 1 1 1 2 1 1 1 2 2 1 2 1 1 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A A G G A T G C A A G C T T C C A A G C T A G G T T C G A T G C T A G C A T C G T T C C T A C G A A G G T T G G T T G G A A G C T T G G A T C C T A C C T A G G T A C C T T C C A A G G T A C C A T G C T A C C A T C C T T C G A A G G T A G G A T G G T T C C A T G G A A G G A A C C A T C C A A G C T A C C T T C C T T G C T T C C A T C G A T C G A A C G A T C C A A G C A T G C A A G G T A C C T T G C T A G C A T C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G T A C G A A G C T T G G T A C G T A G C A A G C T A G G A A G G A T C G T A C C A T G G A T C G A A C C T T C G A A G G T T G C T T C G A A C C T A G G A T C G T T C C T A G C A T C C A T G G T A C G T T G G T T G C A A G C T A C G T A G G A T C C A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A C G A T G C T A C C A A G C A A C C A A G G T A G C T T G G T A C G T T C G T T G C T A G C T T G G A A C C T T G C A T G C T T G C A A C C T A C G T T G C A A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C A A G C T A C C T A G C A A C C A A G G T T C C T T G G T T G G A A G G A A G G A T G G T T G G T A G G A T G G T T C C T T C C T A G C T T G C A A G C A T G G T T G G T T G C A A G C A A C C T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A G C T T C C T A C C A T C G A T C G A T G C A T C G T T G C A T G G A A G G A T C G T A C G A T G C T T G C A A C C A T G C T T G C A A C C A T C C T T G C T A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C T A G G T A C C T A G G T A G C A A C G T A C C T BAO_232 # subpop. label: 3 (internally 3) -2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 1 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 2 1 1 1 2 1 2 2 2 2 1 2 2 2 1 2 2 2 2 2 2 1 1 1 2 1 1 2 1 2 1 1 2 1 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 2 1 1 1 2 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 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A C G T T C G A A G G T A G G A A G G T T G G T T G G T T C C T A G C A T G G T A G C T T C G T A C C A A C G T A C C A A G G A A G G A T C C A A C C T A G C T A G G T T G G A A G C A T G G A T G G T A C C A A G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A G G A A G G T T C G A A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G C T A G G T A G G T T G C A T C C T T C C T T G G T A C C A A G C A T G C A A G G A T C C A A C G A A C C T T C G A T G C T A G C A T G G T T G C T A C G A A G G T A G G T T C G T T G C T T G G A A C C T A G C T A G G T A C G T A G C A A G G A A C C A T G G T A G C A T C G T A G G A T G G T A G G A A G C T A C C A T G C A A G G T T C C A T C C A A G C A A C C T T G G T A G C T T C C A T C C A T C G T A C C A T G C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A C G T A C G A A G G T A G C T T G C T T C C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A T C C T A C G T T C G A A C G T A C G A T G C T T C G A A C C T A C G A T G G A A G C A A G C A A C C A A G G A T G C T T G C T T G C A T C C A T G G T T C G T A G G T T G C A A G C T T C C T T G G A T C C A T C G T A G C A T G C T T G G A A G C T T C G T A G C T A G G A A G G A T G C T T G C T T G G T A C C A T C C T A C C T T G G T A C G T T C G T T G C T A G C T T G G T A C C A A G C A A G C A A C C A A C C T T G C T T G C A A G G T T G C T T C C A T C C A T G G A A G C T A G C T T C C A A G C T A C C T T G G A A C C A T G C A A G C T T G G A T G G T A G C A A C C T A C C T T G G T A G G A A G G T T C C T T C C T A C G T A G C T A G C A A G G T T C G T T G C A A C G T T C G T T G C T A C G T T C C T T G G T T G C T A G C T A G C A A C C A A G G A A G C T T G C A T G G A T G C A A C C A T C C A A C G A T C G A T C G A T G C A T C G T T G C T A G G A A G G A T C G T A C G A T G C T T G C A A C C A T G C T T G G A A G C A T C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G C T T G C T A G C A A C G T A G C T T C C T A G G A T C C T A G C T A G C A A G C T A C G T +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G A A C C A A G G T T C C T T G C A T G G A A G G A A G C T A G G T A C C A T G C T T G C T T G C T T G G T T G C A T G C A T G G T T C G T T G C T A G C A T C G T A C C T A G G A T G G A T C G A A C G A T G C A A G C T T C C T T G C T T G C T A G C A T C G T A G C A A G G A T C C A T C C A T G G A T G G A T C C A T C G A T C C A A C C A A G C A T C C T A G G A T G C T A C C T A G C A A C G T A C C T A G C T A C C A A G G T T G C T A G C T T C C A T G G A A C G T A G C T T G G A A C G A A G G T A C C T A C C A T G G T A G G T T G C T T G C T T G C T A C G A T G C A A C C A A G G T T C C T A G C A T C C A A G G T A G G A A C G T A G G A A C G A A C G A T G C A T C G T A C G T T C G T A C G T A G G A A G G T T G G A A C G T T C C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A A G G T T C C A A C C T A C C T A G G A A G G A A G C A A G G A T C G A A C C A T G C T A C G T T G C A T G C T A G C T A G C T T C C A A G G T A G C A T G C A A C G T A G G A A G C T T G G T T C G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A T G C A T C C T A G G A A G G T A G G T T C G T A G G A T G G A T G C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A G C T A G G T A G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G A A G G T A G G A T G C T A C C A T C C A A G G T T G C A T C G A A G C A A G C A A G C T T G C T T C C A T C G A A C G A A C G A A G C A A G C A T G G A A G G T A C C T T G C T A C G A A G G T A C C T A C C T T G G T A C G T T G C T T G C T A G C T A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G G T A G G T A G C A A G C A A G C T A G G A A C G T A G C T A G C A T G C T T C G A A C C T T C G A A C G T T G C A A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G T T C G T A C G A T G C T T G G A A G C T T C G T A G C T A C G A A G G A T G C T A C C A A G C A A C C A T G G T A G C T A G G T A C G T T G G T A C C A T C C A T G G T T C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G A T G G T T C C A T C C A T C G A A G G A A G C T A C C A A C C A T G C T T G C A A C C A T G G T T C C T T G G A T G G T A C G A A C C T T G C A T G G A A G G A A G G A T C C T T G C A T G G T A C G A A G C T A G G T T G G T T G C A A G C A A C G T T G C T A C G A A C C T T G G T T G C T A G C T A G C A T G C A A G G A A G C T A C C T T C G T A G C A A G C T A C C T A G G A T C C A T C G A T G C A T C G A T G C A A G G A A G G A T C G A A C G A T G C T T C C T A G C A T G C T T G G A A G C A A C G T A C C A A C C A A C C T T G C T A C C T T G C A A G C T T G G A T G C T A G C A A C G T A G G T A C G A A C G A A C C T A G C T A G C A A G C T A C G T BAO_236 # subpop. label: 3 (internally 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C T A G C A T C G T A G C A A G G A T C C A T C C A T C G A A G G A T C C A T C G A T C G T A C G A A G C A A G C T A G G T A G C T A G C T A G G A A C C T A C C T T G C T T G C T A G G T T G G T A C C T T C C T T G G T A C C T A G C T A C G A A C G A A G C T A C C A A C G A A G C T A G G A T G C T T G C T T G C A T C C A T G C A A C C A A G G A A C G A T G C A T C C T T G G T A G G A A C C T A G G A T C G A A C G A T G C T T C G T A C G T T C G T A C G T A G G A A C G T A C G T A G G A A G C T T G C A T G G T T G C A T G G A A C G A A G G A A C C A A G G A A G G A T C C A A C C T A G C T A G G A A G G A T G C A A C C A T G G T A C C A A C C A A C G A A G C A T G C A A G G T A G C T T C C A A G G T A C G A T G C A A G C T T G G A A G G A A C G A T C C A A G G T T G G A A G G T A C G A T G G T A C C T T G C T A C G T A G C A A G G T A G G T T G C T T C C T A C G T A G G T A C C A A G C T A G G A T G C A T C C A A G C T A G G T T C G A T G C T A G C A T C G T T G C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T A G C T A G G T A C G T A G C A A C C T A C C A T G C T A C C A T C C T T G G A A G G T A G G A A G C T A C C A T C C A A G G T T G C A T C G A A G C A A G C A A G C T A G C T T C C A T C G A A C C T A C G A A G C A A G C A T G G A A G G T A C C T T G C T A C G A A G G T A C G T A C G A A G G T A C C T T C C T A C C T T C C A A G C T T G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A T C C T A C G T T C G A A G C T A C G T T G C T T C G A A C C T A C G A T G G A A C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G A T C G T A G G T T G C A A G C T A C G T A G G A T C G T T C G T A G C A T G C T T G G A A G C T T C G T A C C T A G G A A G G A T G C T A C C T A C G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A G C T A C C T T C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G A T G C T A C C A T C C A T C G A A G C A A G C T A G C T A G C T A C C T T G G A A C C A T G C A A G C T T G G T T G C T T G C A A G G A A C C A T G G A A G G A T G G T T C C T T C G T A C C T T G C T A G C A T G G T T C G T T G C A A C G T T C G T T G C T A C G T T C C T T G G T T G C T A G C T A G C A A C C A A G G A A C C T T G C A T G G A T G C A A C C A T C C A A C G A T C G A T C G A T G C A T C G T T G C T A G G A A G G A T C G T A C G A T G C T T G C T A C C A T G C T T G G A A G C A T C C T A C C A A C C A A C C T T G C T A C C T T G C A A G C T T G G A T G C T A G C A A C G T A G C T T C C A A C G T A C C T A G C T A G C A A G C T A C G T +T G C T T G G A T G C T A G C A A G G T T G C T A G G T A C G A A C C A A G G T T G C T T G C T T G G A A G G A A C C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A T C C A T G G T T C G T T G G T A G C A T C G T A C C T A G G A A C C A T G C T T C G A T G C A A G C T T C G T T G G T T G C T A G C A T C G T A G C A A G G A T C C T T C C T T C G T A G G A A C C A T C G A T C C A A G C A T G C T A G G T A C G T T G C T A G G T A C G A A C G A T C C T A G C T A G C T A C C T T G G T A C C T T C C A T G G A A C G T A G C T A C G A A C G A A G C T T C C A A C C A A G G T T G G A T G C T T G G T T G C A A C C A T G C A A C C A A G G A A C C T T G C T T C G T T C C T T G G A A C G T A G G A T C G A A C G A T C C T T C G A A G C T T C G A A G G T T G C A A G G T T G G T T G G T T C C T A G C A T G G T T G C A T G G A A C C A T G G A A G C A A G G A T C G A T C G A A C C T A C C T A G G A A G G A A G C A A G G A T G C T A C C A A C C T A C G T T G C A T G C T A G G T A G C T T C C A A G G T A G C A T G G T A C C T A G G T A G G A A G G T T C G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A T G C T T C C T A G G A A G G T A G G T T C G T A G G A T G G A T G C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A G C T A G G T A G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G A T G G T A G G A T G C T A C C A T G G A A G G A A C C A T C C A A G C A A C C T T C C T T G C T T C C A T C G A A C G A A C C A T C C A A G C A T G C A A G G T A C C T T G C T A C G A T C C T A C G T A C C T A G G T A C C A T G C T T C C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A T C C T A C G T T C G A A C G T A C C A T G C T T C G A A C C T A C G A A C G T T G C A A G C A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T T C C T T G G A T C C A T C G T A G C A T G C T T G G A A G C T T C G T A G C T A C G A A G G A T G C T A C C A A G C A A C C A T G G T A G C T A G G T A C G T T G G T A C C A T C C A T G G T T C C A T G C A T G G T T G C A A C C T T G C T T G C T A G G A T G C T T C C A T C G A T C G A A G G A A G C T A C C A A C C A T G C T T G C A A C C A T G G T T C C T T G G A T G G T A C G A A C C T T G C A T G G A A G G T A G G A T C C T T G C A T C G T A C G A A G C T A G G T T G G A T G C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A G C A A C C A A C G A T C C A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G A T G C T A C C A T G C T T G G A A G G A T C C T A G C T A C C A T C C T T G C T A C G T T G C A A G C T T G C T T G C T A G C A A C G T A G C T T C C T A G G A A C C T A G C T A G C A A G C T A C G T BAO_238 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 1 2 1 2 1 2 2 1 2 1 1 2 2 1 2 2 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 2 1 1 2 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 2 1 2 1 1 2 1 2 2 1 1 2 1 2 2 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 2 2 1 1 1 2 1 2 2 2 2 2 2 2 1 2 2 2 1 2 1 2 1 2 2 2 1 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 1 1 1 2 2 1 1 2 1 2 1 1 1 1 1 1 1 1 2 2 1 1 2 2 1 2 1 2 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 1 2 2 1 2 1 1 2 1 1 2 2 1 2 2 2 2 2 2 2 1 1 1 2 2 1 1 2 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 1 1 2 2 1 2 2 1 2 2 1 2 1 2 2 2 2 1 1 2 1 1 1 2 1 1 1 1 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 2 1 1 2 1 2 1 1 2 1 1 2 1 1 1 2 1 2 1 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 1 1 2 1 2 1 2 2 1 1 2 2 2 1 2 2 1 1 1 1 1 2 1 1 1 1 2 1 2 2 2 1 2 2 2 2 1 2 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 2 2 1 2 1 2 1 2 2 1 1 1 2 1 2 2 1 1 1 2 1 2 2 1 2 2 1 2 2 1 1 2 1 2 2 1 2 2 1 2 2 1 2 1 2 2 1 1 2 2 2 1 1 2 2 2 2 1 1 2 1 1 2 1 2 2 2 1 2 2 1 2 1 1 1 1 2 2 1 1 1 1 2 1 2 2 1 2 2 1 2 2 2 2 1 1 2 2 2 2 1 2 2 1 2 2 2 1 2 1 2 2 2 1 1 2 2 1 1 1 2 1 2 2 2 2 1 2 1 2 2 2 2 2 2 1 1 2 2 2 1 1 1 2 1 2 1 1 1 2 2 1 2 2 2 1 2 1 2 2 2 1 2 2 1 1 1 1 2 1 1 2 2 2 1 1 1 2 2 1 2 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 1 1 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 2 1 2 2 2 1 1 2 1 1 1 2 2 1 1 1 1 2 2 1 2 2 2 1 1 1 2 1 2 2 1 1 1 1 1 2 1 2 2 1 2 1 2 2 1 1 1 2 1 2 1 2 1 2 2 2 2 1 1 2 2 2 2 2 2 1 1 2 1 1 1 1 1 2 1 2 2 2 1 1 2 1 1 2 2 2 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 2 2 2 1 1 1 2 2 1 2 2 1 1 2 2 2 2 2 1 2 2 2 1 1 2 1 2 1 2 2 2 2 2 1 1 1 1 1 2 2 2 1 1 1 2 1 1 2 1 2 2 1 1 1 2 2 2 2 2 1 2 2 2 1 1 2 2 2 2 1 2 2 2 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 1 2 1 2 2 2 1 1 1 1 2 2 2 2 1 1 1 1 1 2 1 1 2 2 2 1 1 1 1 1 2 1 2 2 1 1 2 2 1 2 2 1 2 2 2 2 1 2 2 1 1 1 2 2 2 2 1 2 2 1 1 2 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 2 1 2 1 1 1 1 2 1 1 1 1 2 2 2 1 1 1 1 1 2 1 2 2 1 1 1 2 2 1 1 2 2 2 2 2 2 2 1 1 1 2 2 1 1 1 2 2 2 2 1 2 1 2 2 2 1 2 1 2 1 1 2 1 2 2 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 2 2 2 2 2 2 2 2 1 2 2 2 2 1 2 2 1 2 2 1 1 1 2 2 2 1 2 1 2 1 2 2 1 2 2 2 1 2 2 2 2 2 1 1 1 2 2 2 2 1 2 1 1 1 2 2 1 1 1 1 2 2 1 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 1 1 2 1 2 1 2 1 1 2 1 1 2 2 1 2 1 2 1 2 1 1 2 2 1 1 1 2 2 2 1 2 1 2 1 2 1 1 2 2 1 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 2 2 1 1 1 2 2 2 1 1 2 1 2 1 2 1 1 1 2 2 1 2 2 2 2 2 1 1 2 2 2 2 2 2 1 1 1 1 1 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 1 2 2 1 1 2 1 1 1 2 2 1 2 2 2 2 2 1 2 1 2 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C G T T C G A A C C T A C C T A G G T T G G A T G C A A C C A T G G T A C C A A C C T T C G T T G C A T C C A A G G T A C C T T C C A A G G T A C C T T G G T A C G T A G G A A G C T T C C A T G G T A G G T A C C A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A G G T A G G T T G C T T C C T T C G T T G C T A C C A A G C T A G G A A G C A T C C A A C G A A G G T A G G T T G C T T G C A T C G T T C C T A C G A A G G T A G C T T G G A A G C T T G G A T C C T A G C T A G C A T G C T T G C T T G G T A G C T T G C T T C C A T C C T T C G A A G G T A G G A T G G T A C G A T C C A A G G T T G C A T C C A A C C A A G C T T C C T A G C T T C C A T C G A A C C T A C G T T C C T A G C A T G G T A G C A A G C T T G C T A C G A T C G T T C C T A C G A A G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T A C C T A C G T A G C A A G C T A G G A A C G A A G C T A C G T T G C T T C G A A G C T T C G A T G G A A G C A T C G A A C C T T C C T T G C A A G C T T G C A T C C T A G G T A C G T A G G T T G C A A G C T A G C T T G G A T C C A T C G T A G G A T C G T T G C A T C C T T C C T A G C T A C G A A G G A T G C T A C C A A G C A A C C A T G G T A G C T A G G T A C G T T G G A A G C T A G C T T G C T A C C T T G C A T C C T A C C A A C C T T G C T T G C T A G G A T G C T A C C A T C C T T C G A A G G A A G C T A G C T A G C T T G G T A G G A A C C A A C G T T C C T T G G T T G G A A G G A T G C T T G G T T G G A A G G A A G G A T C C T T G C A T G G T A C G A A G C A T G G T T G G A T G C A A G C T A C G T A G C T A C G A T C C T T G G T T G C T A G G T A G C T A C C A A G C A A G C T T G C A T G G A T G C A A G C T A C C A A G G A T C C A T C G A A G C T A G C T T G C A A G G T T C G A T C G A A C G A T G C T T G C A A C G A T G C T T G G A A C C A A C C T T C C A A C C A A C C T T G C T A C C T T G G A A G C T T G C A T G C T A G C A A C G T A G G A T C C A A G C A T C C T A G C A T G C A A C C T A G G T +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G A A C C A A G G T T C C T T G C A T G G A A G G A A G C T A G G T A C C A T G C T T G C T T G C T T G G T A G C A A C C A T G G T A C G T T G G T A C C A T C C T A C C T A G G A T G G A T C G A A C G A T G C A A G C T T C G T T G C T T G C T A C G A T C C T A G C A A G G A T C C A T C C A T G G A A G G A A C G A A G C T T C C A A G C A T G C A A G G A A G G A T G C T A G C T A G C A A G C T A C C T A G C A A C G T A G G T T C C T A G C T T C C A A G C T A C G T A G C T T G G A A C C A A G C T T C C A A C G A A G G T T G G T T G C T T G C T T G C T T C C A T G C A A C C A A G G T T G C T A G G T T C G T A G G T A G G A A C G T T G G T A C G A A C G A T C C A A C G T A G C A A C G T A C G T A G G A A G G T T G G T T G G T A G C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A T G C A T C C A A C C T A C C T A G G A A G G A A G C A A G C A T C G T A C C A T G C T A C G T T G C A T G C T A G G T A G C T T C G A A G G T A G C T T G C A A C G T A G G A A G G A A G C A T G G A T C C T A C C A T C G T A C C A T G G T T C G T T G C T T C G T T G C A A G G A A G G T T G G A A G C T T C C T T G G T A C C A A G G A T G C A A G C T A C C A A G G A A G G T A G G T T C G T A G G A T C G T T C C T A C C T A G G A T G G T T C G T T G C T T G G A T C C T A G C T A G G T A C G T A G C A A G G T A C C A T G C T A C C A T C G T T C C T T G C A A C C A T G G A A C C A T C G A A G G A T C C A T C C A A G C A A C C T T G C T T G C T T C C A T C G A A C G A A C C T T G G A T G C A T G C A A G G T A C C A A G C T A C G A A G G T A C G T A C C A A G G T A G C T T G C T T C C A T C C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A C C T A G G T T G C A A G C T A C G A A G G A A G C T A C G A T G G A T C G A A C C T T C G A T G G A A G C A A C G A T C C T T C C T T G C A A C C T T G C A T C C A T G G A T C G T A G G T T G C A A G C T T C C T A G G A T G G A T C G T A G G A T G C T T G G A A G C T T C G T A C C T A C G A A G G A T G C T A G G A T G G T T G C A T G G T T G C T A G G T A C G T T G G A T G C T A G C T T G C T A C C A A G C A T C C T A C C A A C C T A C G T T G C A A G G A T G C T A C C A T C C A T G G T T G G A A G C T A G C T A G C T A C C T A G G A A G C A T C G T T C C T T G G A T G G A A G G A A C C T T G C A T G G T A G G A A C G A T C C T T C G T A C G T T G C T A G C A A G G T T C G T T C C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C T T C C T T G C A A C C T A C C A A G C A T C G A T C G A A G C A T C G T T G C A A G G A T C G A A C G T A C G A T G G T T G C A A C G A T G C T T G G A A C C A A C C T T C C A A C C A A C C T T G C T A C C T T G G A A G C T T G C A T G C T A G C A A C G T A G G A T C C A A G C A T C C T A G C A T G C A A C C T A G G T BAO_240 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 2 1 2 1 2 2 1 2 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 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2 +T G C T A G G T T C C T A G C T A C C T T G G A A G G A A C C A A C C A A G G T T C C T T G C A T G G A A G G A A G C T A G G T A C C A T G G T T G C T T G C A T G C T A G C A T C C A T G G T A G C T T G C A A G C A T C C T A C C T A G G T A C C A T C C T T C G T T G C T A G C T T C G T T G C T T G C T T G C A T C C T A G C A T G C A T C C T T C C A T G G A T G G A T C C A T C G A T C G T A C G A A G C A A G C T A C G T T G C T A G C T A C G A A C G T A C C T T G C T T G C T A G G T T G C T A G C T T C C A A G G A A C C T A G C T A C G A A C C A A G C T T C C A A C G A A G G T T G G A T G C T T G C T T G C T T C C A T G C A A C C A A G G A A C C T T G C A A C G A A G G T A G C A A C C T A C G A A G G A A C G T T G C A T C G T A G C T T C C T A C G T T G G A A C G T A C G T A G G A A G C T T G C T T G G T A G C A T G G A A C G A A G G A A C C A A G G A T G G T T C G A A C C T A G C T A G G T T G G A T G C A A C C A T G G T A C C A A C C A A C G A A C C A T C C A A G G T A G C T T G G 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T T C C T A C C T A G C T T G G A T G C T A C C A T G G T A C C A T G G T A G C T A G G T A C G T T C G T A G C T A G C T A C C T T C C T T G C A T G G T T G C A A C C T T G C T A G C T A G G T T G C T A C C A T C G T T C G A A G G A A G C T A G C T A G G T A G G T A G G A A C G A T G C A A G G T T G G A T G G A A G G A A G C A A C C T T C G A A G C A T G G T T C C T T C G T A C G T A G G A A G G T T G C T T G G T T C C A T G C T A C G T T G C T A C G A A C C T T G G T A G G A T G G T A G C T A C C A A G G A A G G A T G C A T C G T A G C A A C C A A C C T A G C T T C G A T C G A A G C A T G G A T C G A T C G A A G G T T C G A A C G A T G C T T C C T A C G A T G C T A G G A A G C T T C C T A G C T A C C A A C C A T C C T A C G T T G C A A G C T T G C T T G C T A G C A A C G T A G G T A G G A A G G A A C C T A G C T A G C A A G C T A C G T +T G C T A C G T A C G T T C C T A C C T T C G A A G G A A C G T A C C A A G G A T C C T T G C T T G G A A G G A A G C T A G G T A C C T A C C T T G C 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T A C C A A C C T A C G T T G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G C T T G G T A G G A A C C A T G C T T C C T A G G A T G G T A G C A A G C T A C G A T G G T A G G A T G G T T C C T T C C T A C G T T C G A A G G T A G G T T G G T T G C A A G C A A C G T T G C T A C G T T C C T T G G T A G C T T C G A A G C T A C C A A G G A A G C T T C C A T C G T A G C A A C C A A C C A A G C A T C G A T G G A T G G T T G G T T G C T A G G A A G G A T C G A A C G A T G C T T C C T A C G A T G C T T G G A A G G A T C C T A G C T A C C A A C C T A C C T T C C T T G C A A G C T T G G T T G C T A G C A A C G T A G C A A C C A A G G A T C C T A G G T A G C A A G C T A C G T BAO_245 # subpop. label: 3 (internally 3) -1 2 2 2 1 2 1 2 1 1 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 2 2 1 2 2 1 1 1 2 1 2 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 2 1 2 1 1 2 1 1 2 2 2 1 2 1 1 1 2 1 2 1 1 1 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 1 2 1 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C A A C C A A G G T A G G T T G C T T G G T T G C A T C C A T G C A A C C A A G G A T C C T A G C A T C G A A G G T A G C A A C C T A G G A A C G A A C G T T G C A A C G T A C G T T C G A A G G T T C G A A C G T T G G A A C G T T C C T T G C A T G G T T G C A T G G A A C G A A G G A A C C A A G G A A G G T T C G A A C C T A G C T A G G A A G G A A G C A A C C A A G G T A C C A A C C A A C G A A C C A T G C T T G G T A G C A T C C A A G G T A G C A T G G A A C G T A G G T A G G A A G G T T C G T A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C A T C C T T C C T T G G T A C C A A G C A T G C A A G G A T C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A C G A A G G T A G G T T C G T T G C T T G G A T C C T A C C T A G G T A C C T T G C T T G G A A C C T A G C T A C C A T C C T T G G A T G G T A G G A A G C T A C C A T G G A A G G T T C C A T C G A A G C T A C C T T C C T T G C T T C C A T C G A A C G A A C G T T C C T A G C A T G G T A G C A A G C T T G C T A C G A T C C T A C G T A C C A A G G T A G C A T C C A A C C A T C C A A C C T T G C A T C G A A G C A T C C A T G G T A C G A T G C T A C C T A G C A A G C A A G C T A C G T T C G A T C G T A G C T T G C T T C G A A G C T A C G A A C G T T G C A A C G A T C C T T C C T T G C A A C C T T G C A T C C A T G G A A C G T T G G A T G C A A G C T T C G T A C G A T G G A T C G T A G G A T C G T T C G A A C C T A C G T A C C T A G C T A G G A T G C T A C C T A G C A A C C A T G G T A G C T A G G T A C G T T G G A T G C T A G C T A G G A A C C T T G C A T G G T T G G A A C C T A C G T T G C A A G G T T G C T T C C A T C G A T C G A T G C A A G C T A G C A A C C T T G G T A G G A A C C A T C G T T C G T T G G A T G G T A G C A A C C T A G C A T G G T A G G A A C G A T C C T T G C A T G G T A C C T A G C A T G G T T G G T T C C A A G C A A C G T T G C T A C G T T C C T T G G T A G C T A G C T A G C A T G C A A G C A A G C T T C C A T C G T T G C A A G C A A C C A A C C A T C G A T C G A A G C A T C G A T C G T A G C A T G G T A G C T A C G A A G C T T C C T A G C A T G C T T G G A A G C T T C C T A G C T A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A G G A A C G T T C C T A G C T A G C A A G C T A C G T +T G C T A G G T T C C T A G C T A C C T T C G A A G G A A C G T A C C A A G G A T C C T T G C T A C G T T G G A A G C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A T C C A T G G T T C G T T G C T T C C A T C G T A C C A A G G A A C C A T C G A A C G A T G C A A G C T T C G T T G G T T G C T T G C A T C G T A G C A T C C A T C C T T C C A T C G A A G G A T C C A T C G A T C G T A C G T A C C A A G C T A G G T T G C T A G C T A C G A A C G A T C C T A G C T A G C T A C C T T G G T A C C T T C C T T G G T A C C T A G C T A C G A A C G A A G G T A C C A A C G A A G G T T G G A T G C T T G G T T G C A T C C A T G C A A C C A A G G T T C G A T G C T A C G T A C C T A G C A A C C T T C C A T C G A A C G A T G C A T C G T A G C T A C C T A C G T A G G A A C G T T C G A A C G A A G C T T G C A T G G T T G C A T G G A A C C A A G G A A C C A A G G A A G C T A G G A A C C T A C C T A G G A A G G A T G C A A G C A T G G T A C C A T G C T A C G T T G C A T C C A A G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T T C G A A G G A A G G T A C C A A G G T A C G A T G G T A C C T T G C A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G C T A C C A A G C T T G G A A G C A T C C T A C G A A G C T T C G A T G C T A G C A T C G T T C C T A C C T A G G A T G G T T C G T T G C T T G G A A C C T A G C T A G G T A C G T A C C A A G G A A C C A T G G T A G C A T C G T A G G T T G G T A G C A A G C T A C C A T G C A A G G A A C C A T C G A A G C A A C C T T G G T A G C T T C C T A G C A T C G A A C C A A G C A A G C A T G G A A G G T A C C T T G C T A C G A A G G T A C G T A C C T A G G T A C C T T G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A A G C T A C C T A C G T A G C A A G C T A G G A A G G A A C G T A C C A T G G A T C G A A C C T T G G A A C G T T G C A A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T T G C A A C C A A G C T A G G A T G G A T C G T A G G A T G C T T G G A A G C T T C G T A C C T A G G A A G G A T G C T A C C T T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C T A G G A A C C T T G C A T C C T A C G A A C C T A C G T T G C A A C G A T G C T A C C A T C C T T C G A A G G A A G C T A C C A A G G T A G G T A G G A A C C A T G C A T G C T T G G T T G G A A G G A A G G A A G G T T G G T A G G A A C G T T C C T T G C A A G G T T G C A A G C T A G G A T G G A T G C A A G C T A C G T T G C T T C G T T C C T T G G T A G G A T C G A A G C T A C C A A G G A A G C T T C C T T C C T T G C A T G G A T C C T A G C A T C G A T C G A A G C A T G G T T G C T A G G T T C G A T C C A A C G A T G C T T G C A A G C A T G C T T G G A A G G A T C C T A G C A A C C T A C C T T G C T A C C T T G G A A G C T T G C A T G C T A G C A A C G T A G C A T G C T A G G T A C C T A G G T A G G T A G C A A C G T BAO_246 # subpop. label: 3 (internally 3) -1 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 2 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 1 2 1 2 1 1 1 1 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 1 2 2 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 1 1 2 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 2 2 2 1 2 1 1 1 2 2 1 1 1 2 2 2 2 2 2 2 2 1 2 1 2 1 1 2 1 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 2 1 2 1 2 1 2 2 1 1 2 2 2 2 2 2 1 1 1 2 2 1 1 2 2 1 2 2 1 2 1 2 1 1 1 2 2 1 2 1 2 1 2 1 2 2 2 1 2 2 2 1 2 2 2 1 1 2 1 1 2 2 1 2 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 1 1 1 2 1 1 2 2 2 2 2 1 2 1 1 2 1 1 2 1 1 1 1 1 2 1 1 1 1 2 2 1 2 1 1 2 1 2 2 1 2 1 1 2 2 1 1 2 2 2 1 1 2 1 2 2 1 1 1 1 2 1 1 2 1 1 2 2 2 2 2 1 1 2 1 2 2 2 2 2 1 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G C T A C C T T G C T T G C T T G G T A G C A T C C A T G G T T C G A T G G T A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C G T T G C T T G C T T C C A T C C T A G C A T C C A T C C T T C C A T G G A A G G A A C C A T C G A T C G A A C G A A G C A A C G A A G G A T G C T A G C T A C C A A C G T T C C T A G C T A G C T A G G T T G C T A C C T T G G T T G G T A C G T A G C T A C G A A G G A A G G T A C C A A C G A A G G T T G G T T G C T T G C T T G C T T C C A T G C A A C C T A G G T A C G T T G C T T C G T T C C T A G C A A C G T T C C A T C G A A C G A T G C A A C G T T G C A A C G T A C G T A G G A A C C T T C G A A C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A C C A A G G A A G G T T G G A A C C A T C C T A G G A A G G A T G C A A G C A T C G A A C C A A C C A A C G T A C C A T G C T A G C T A G C A T C C T A G G T A C G T T G G A A G C T A G G A A C G T A G C A T G G T A G G A T G G A A G G T A C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G G T T C C T T C G T T G G T A C C A A G C A T G G A T G C T T C C A A G C T A G G T T C G A T G C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C T T C G A T C C T A G C T A G G T A G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G A A C C T A G G A T G C T A C C A T G C A T G C T T G C A T C C A A G C A A C C T T C C T T G C T T C G A A G C A T C C T A C C A A C C A A G C A T G G A A G C A A C C T T G C T A C G A T C C T A C C T A C C A A G G T A G C A A G C T T G C T T C C A A C C T T G C A T C G A A G C T T C C T T G G A A C G A A G C T A G G T A G C A A G C A A G C T A G G A T C G A T C G T A C C A T G G A T C G A A C C T T G G A A C G T T G C A A C G A T C C A A G G A T G C T T G C T A G C A T C C A T G G A A C G T A G G A T G C A A C C A A G C T T G G A T C G A T C G T A G G A T C G T T C G A A C C T T C C T A G C T A G C T A G G A T G C T A C C A A C G T A C C A T G G T A G C T T G G T A C G T T C G A A G C T A G C T A G G T T C C T T G C A T G G T T G C A A C C T T G C T T G C T A G G A T G C T A C C A T C C A T G G A A G G A A G C T A G C T A G C A A C C T A G G A A C C A T C G T T C G T T G G A T G G A A G G A A G G A T G G A T G G T A G C A A C G A T C G T T C C T A G G T A G C A A G C T A G G T T G G T T G C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T G C T T C G T A G C A A G C A A C C A A C C A T C G A T C G A T G C A T C G A T C G T A G G A T G G A T C C A A C G A T G C T T C C T A G C T T G C A T G G A T G C A T C C T T G C T T C G A A G G T T C C T A C G T T G C A A G C T T G C T T G C T A G C A T C C T A G C A T C C A A G C T A C G A T G C T A G C A A G C T A C G T +A C C T T G G A T G C T A G C T A C C T T C G A A G G T A C G A A G C A A G G A T C C T T G C T T G G A A C G A A G C T A G G T A C C T A C C T T C C T A C C T A G C T A G C A T C C T T G G T A C G T T G G T A C C A T C G T A C C T A G G T A C C A A G G A A C G T T G C A A G C T T C C T T G G T T G C T A G C A T C G T A G C A A G G A T C C A T C C A T C G A A C C T A C G A T C G A A C G T A C G T A G C A A C G A A G C T T G C T A G C T A G C A A C C T A C C T A G C T T G C T A G G T T C C T A G C T T C C A A C G T A C C T A G C T A C G A A G G A A G G T A C C A A C G A T G C T A G G A T G C T T G C T T G C A T C C A T G C A A C C A A G G T T C C T A G C T A C G T A G G T A G C A A C C T A G G A T C G A A C G A T G C A A C G T A C G A A C G T A C G T A G G A A G G T T C G A T C G A A G C T T G C A T G G T T G C A T G G A A C G A A C G T A C C A A G G A A G G A T C G A A C C T A C C T A G G A A G G A A G C A A G G A T C G T T C C A A C C T T C G T T C C A T G C A A G G T A G C T T C C A A G G T A G C T T G G T A C G T A G G A A C G T A G G A T G G T A G G T A C C A T C G T A C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T T C C T A C G T A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G G T T C G A T G C T A G C A T G G A T G C T A C G A A G G T A G G T T G G T T G C T T G G A T C C T A G C T A G G T A C G T A C C A A C C T A C C A T G C T A C C A T C C T A G G A T G G T A G G A A G C T A C C A T G G A A G G A A C C A T C C A A G C A A C C A A G C A T C C T T C G T T C G A A C G A A C C A T C C A A G C A T G G A A G C A A G C T T G C T A G C A A C G T T C C T A C C T A G G T A C G T T C C T A G C T T C C A A G C T A G C A T C G A A G C T T C C T T G G T A C G A T G C T A G G T A C C A A G C A A G C T A C G T T C G A A G C T A C C A T G C T T C G A T C C T T C G A T G G A A G C A A C G A T C C T A G G A T C G T T C C T A G C A T C C T A G G T A C G T A G G T A G C A A G C T A C G T A G G A T C G T T C G T A G G A T C G T T G G A A G C T T C G T A G C T A G G A A C G A A G C T A C C T T G G T T G C A T G G T T G C T A G G T A C G T T C G A T G C T T C C A T G G T A C C T T G C A T C C T T G C A A C C T A C G T T G C A A C G A T G C T A C C A T C C A T G G A T G G A A G C T A G C T A G G T A C C T A G C A A G C A T G C T T C C T A G G A T G G T A G G A A G C T A C C T T C G T A G C A A C G T T C C T T C G T A C G T A G G A A G G T A G G T T G G A T G C A A G C A A C G T T G C T A C G T T C C T T G G T A G C T T C G T A G C A T G C A A G G A A G C T T G C A T G G A T G C A A G C A A C C T A G C A T C G A T C G A T G C A T C G T T C C A A G G A T C G T T C C T A C G A T G C T T G C A A C G A T G C T T G G A A G G A T C C T A G C A A C C A A C C T T G C T A C G T T G C A A G C T T G C T T G C T A G C A A C G T A G G T T G G A A C G T A C C T A G C T A G C A A G C T A C G T BAO_249 # subpop. label: 3 (internally 3) -2 1 1 2 2 2 1 1 1 2 2 2 2 2 2 2 2 2 1 2 1 2 2 1 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 2 1 2 1 2 2 2 2 1 1 1 2 1 1 2 1 2 2 1 1 2 1 2 1 2 2 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 2 1 1 2 2 1 1 2 1 2 1 1 1 1 1 1 1 1 2 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T C G A A G G T A C G T T G C A A C G T A C G T T C G A A G G T T G G A A C C T T C G T A G G A A G C T T G C T T G G T A G C A T G G A A C G A A G G A A C C A A G G A T G G T T C G A A C C T A C C T A G G A A G G A T G C A A G C A T G G T A C C A A C C A A C G T T G C A T G C A A G C T A G C A T C C A A G G T A G G A T G C A A G C T T G G A A G G A A G G A T C C A A G G T T G G A A G G T A G C A A G G T T C C T T G C A T G G T T G G A A G G A A G G T T G G A A G C T T C C T T G G T A C C A T G C A T G C A T G C T A C C T A G C T A G G T T G C T A C C T A G C A T C G T T C C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A G C T A G C T T G C A T G C A A G C T A C C T T G C A T G C A T C C T A G G T T G G T A G C A A G C T A C C A T C G A A G G T T G C A T C G A A G C T A C C T T C C T T G C T T C C A T C G A A C G A A C G A A G C A A G C A T G G A A G C A A C C T T G C T A C G A T C C T A C G T A C C A A G G T A G C A A G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C T T G G A A C G A T G G T A G G T A C C A A G C A A G C T A G G A A C G A A G C T A C C A T G C T T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T T C C T A G G A T G G A T C G T A G G T A G C A T G C A T C C T A C G T A G C T A G G A A G G A T G C T A C C A T G G T T G C A A G G T T G C T T G G T A C G T T C G T A G C T A G C T A C C T T C C A T G C A T G G T T G C T A C C T T G C T A G C T A G G A T G G T T C C A T C G T T C G A A G C A A G C T T C C A A G G A A C C T A G C A A C G A T G C T T C C T A G G A T G G T A C G A A G C T A C C T T C G A A G C A T G G T T C C T T C C A A G C T T G G A A G C T A G G T T G G T T G C A A G C T A C G T T G C T A C G T T C C T T G G T A G C T T G C T A G C T A C G A A G G A A G C T T C C T T C G T A G C A A C C A A C C T A G C A T C G A T G G A T G C A T G C T T G C T A G G A T G G A T C C T A C G A T G C T T C C T A C G A T G C T T G G A A G C A T C C T A G C T A C C A T C C T T C C T A C G T T G C A A G C T T G C T T G C T A G C T A C G T A G C T T C C T A G G T T C C T A G C T A G C A A G C T A C G T +T G C T A C G T A C C T T C C T A C C T T C G A A G G A A C G T A C C A A G G T T G C T T G C T T G G T T C G A A G C T T G G T A G C T A C C T T G C T T G C A T G G T A G C A T G C A T G G T T C G A T G G T A G C A T C G T A C C T A G G A A C C A T G C T T C G T T G C T A G C T T C G T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C C A T G G A T G G A A C C A T C G A T C G T A G C A A G C A A G C A A G G T T G C T A G C T A C G A A C G T A C C T T G C T T G C T A G G T T G C T A G C T T C C A A G G T A C C T A G C T A C G A A C G A A G G T A C C T A C G A T G G T A G G T T G C T T G C T T G C A A C C A T G C A A C C A A G G T A C G A T G C T A C G A A C C T A G G A A C G T A G G A A C G A A C G A T G C A T C G T A G C T A C G T A C G T A G G A A C G T A C G T A C G T T C C T A G C A T G G T A G C T T C G T A C C A A G G A A C C A A G G A A G G T T C G A A C C T A C C T A G G T A C G A T G C A A C C A T G G T T C C A T G C T T C G A A C C A T G C A A G G T A G C T T G G A A G G T A C C T T G G T A G G T A G G A A C G T T C C A T C G T A G G T A C C A T C G T A C C A T G G T T C G T T G C T T C G T T G C T A G G A A G G T T G G T T C C T T C G T T G C T A C C A A G C A T G C A A G C A T C C T A G C A A G G T A G C T A C C T A G C A A G G T T C C T A C G A A G G T T G C T T C G T T G C T T G G A T C C T A G C T A G G T A C G T T G C A A C C T A C C A T G C A T G C A T C C T T G G T T G C A A C C A T G G T A C C A T C G A A G G A A G C A T G C A A C C T A C C T T G C T A G C T T C G T T C G A A C G A A C G A A G C A A G C A T G G A A G C A A C C T T G G T A C G A T C C T A G G T A C G A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T T C C T A C G T A G C A T C C T A C G A A G G A A G C T A G C T T G C T T C G A T C C T T C G T A G G T T G C A A G G A T C C T A G G A T C G T T C C T A G C A T C C A T G G T A G G T A G G T A G C A A G C T A C C T A C G T A C C T T C G T A G C A T G C T T G G A A G C T T C G T A C C T A G C T T G G A T G C T A C C T T G G T A C C A T G G T A G C T A G G T A C G T T C G A A G C T A G C T T G C T A C C T T G C A T G G T A C C A A C C T T G C T A G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G G T A G G T A G G A A C C A T C G T T C C T T G G T T G G A A G G A A G C T A G G A T G G T A G G A T G G T T C C T T C C T A C G T T C G A A G G T T G C T T G G T T G C A A G C A A C G T T G C T A C G A A C C T T G G T T G C T T G G T A G C T A C C A A G G A A G G A T G C A T C G T A G C A A C C A A C C T A G C T T C C A T C G A T G C T T G G T T G C A T G G A A G G A T C G A A C G A T G C T T C C A A C C T T G C T T G G A T G C T T C C T A G C T A C C A A C C A T G C T A C G T T G G A A G C T T G G A T G C T A G C A A C G T A G G T A G G A A G G A T C C T A G G T A G C A A G C T A C G T 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T T G C A A G C A T G C T A C C A T G G A A G G T T G C A T C G A A G C A A G C T T C C T T G C T T C C A T C C A A C G T A C C T T C C T A G C A T G G T A G G T A G C T T G C T A G C A A C G T A C C T A C C T A G G T A C G T T C C T A C C T T C C A A C C T T G C A T C G A T G C A T C C T T G G A T C G A A G C T T C C T A C G T A G C A A G C T A G G A A G G A A G C T A C C T T G C T T C G A A C C T A C G A A C G A A G C A A C G A T C C T T C C T T G C T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T T C C T A C G A T G G A T C G T A G G A T C G T T G G A T C C T A C C T A C C T A G C T A G G T T G C T A C C T T G G T T G C T A G G T A G C T T G G T A C G T T C G A A G C T A C C A T G G T A C C T T G C A T G G T T G C A A C C T T G C T T G C T A G G A T G G T T C C A T C G A T C G A A G G A A G C T A C C A A C C A T G C T T G C A A C C A T C G T T C C T T G G A T G G T A G C A A C C A T C G T T G G A A G G A T G G T T C C T T G C A T G G T A C G A A G C A A G G T T C G T T G C A A G C T A C C T A G C T T C G A A C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T G C T T C G T A G C A A G C A A C C A A G C A T C G A T C G A A G C A T G G T T G C A T G G A T C G A A G C A A C G A T G C T T C C T A G C T T G C T T G G A A G C T A C C T A G C T T C G A A G G T T C C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C A T G C A A C G T A C C T A G C T A G C A A G C T A C G T BAO_260 # subpop. label: 3 (internally 3) -1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 1 1 2 2 2 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 1 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 2 1 1 2 1 2 1 1 1 1 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 2 2 2 1 1 1 2 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 1 2 2 2 1 1 1 1 2 2 2 1 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 2 2 1 2 2 2 1 2 1 2 1 1 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 1 2 2 1 2 1 1 2 1 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C C A A G C A T G G A A G G T A C C T T G C T A C G A T C C T A C G T A C C A A G G T A G C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G G T T C C T A C C A A G C A A G C T A C G T T C G A T C G T A C C A T G C T T C G A T C C T T C G A A C G T T G C A A C G A T C C T A G G A T G C T T C C T A G C A T C C A T G G T A C G T T G G T T G C A A C C A A G C T T G G A T G G T T G G T A G G A T G C T T G G A T C C T A C G T A C C T A G G A A G G A T G C T A C C T T G G T T G C A A G G T T G C T A G G T A C G T T C G A T G C T A G C T A C C T T C C A T G C A A G C A A C C A A C C T A C G T T G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G C T T G G T A G G A A C C A T C G T T C G T T G G A T G G A A G G A A G C T A G C A T G G T T C G A T C G T T C C T T G C A T G G T A C C T A G C A A G G T T G G A T G C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T T G G A A G C T A C C A A G G A A G C A T C C A T G G T A G C A A C C A A C C T A G C A T C G A T C G A T G C A T G C A T G C T A G G A T G G A T C G T A C G A A G G A T G C T A C G A T G C T T G G A A G C T A C G T T C G A A C C A T C C A T C C T A C G T T G C A A G C T T G C T T G C T A G C A T C C T A G G T A G G A A C G A A G C A T G G T A G C A A G C T A C G T BAO_262 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 2 1 1 2 2 1 2 2 1 1 2 1 1 2 1 1 1 2 2 2 2 1 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 1 2 1 2 1 1 1 1 1 2 1 2 2 2 2 1 1 1 2 2 2 1 2 1 2 2 1 1 1 2 2 1 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 2 1 1 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 1 2 1 2 2 2 1 2 1 2 1 2 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 1 2 1 1 2 1 1 2 1 1 2 2 2 2 2 2 1 1 1 2 1 2 1 2 2 1 2 1 1 2 1 2 1 1 1 2 2 1 2 1 2 1 1 1 2 2 2 1 2 2 2 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 2 1 1 1 1 2 2 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1 1 2 2 2 2 2 1 1 2 2 1 2 1 2 2 2 2 1 2 +T G C T A C G T A C G T T G C T A C C T T G G T A G G T A C G T A C G A A G G T T C C T T G C A T G G A A C G A A G C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A T C C A T G G T T C G A T G G T A G C A T C C T A C C A A G G A T G C A T G C A A C G A T G C A A G C T A C G T T G G T T G C T T G C A T C G T A G C A A G G A T C C A T C C A T C G A A G C T A C C A A G C T T C C A A G C A A C C A A C G A A G G T A G C T A G C T A G C A A C G T A C C T T G C T T G C T A G G T T G C T A G C T T C C A T G G A A C G T A G C T A C G A A C C A A G G T T C C A A C G A A G G T T G G A T G C T T G C T T G C A A C C A T G C A A C C A A G G A T C C T A G C T A C G T A G G T A G C A A C G T A G G A A C G A A C G A T G C A T C G T A C G T T C G A A G G T T G G A A C G T A C G T A C G T T C C T A G C A T G G T A G C T T C G T A C C A A G G A A C C A A G G A A G G T T C G A A C C T A C C T A G G A A G G A A G C A A G C A T G G T A C C A A C C T A C G T A G C A T G C A A G C T A G C A T C C A A G G T A G G A T G C A A C G T A G G A A G G A A C G T T C G T A G G T T G G A A G G T A G C A A G G T T C C T T G C A T G G T T G G A A G G A A G G T T G G A A G C T T C C T T G G T A C C A T G C T A G G A T G C A A C C A A G G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T T G C T T C G A T G C T T G G A T C C T A G C T A G C T T G C A A C C A A G C T A C C A T G C T A C C A T C C T T C G A A C C T A G C A T G G T A C C A T C G A A G G A A C C A T C C A A C C A A C C T T G G T A G C T T C C A T C C A T C G T A C G T A G C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T G C T T G C T T C C T A C C T A G C A T C G A A G C A T G C T T G G A A C G A A G C T A C C T A C G T A G C A A C C T A G G T A C G A A G C T A C C A T G C T T C G A A C C T A C G A T G G A A C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C A A G C T T G G A T C C A T C G T A G C A T G C T T G G A A G C T T C G T A C C T A G C T A G G A T G C T T G C T T G G T T G C A A G G T T G C T T G G T A C G T T C G A A G C T A G C T T G C T T C C T T G C A T G G T T G C A A C C T T G C T T G C T A G G A T G C T T C C A T C C T T C G A A G C A A G C T T C C A A G G T A C C T T G C A A C C A A C G T T C C T T G G A T G G T A G G A A C C A A C G T T G G T A G G A T G G A T C G T T C C T A C G T T G C A A G C T T G G T T C G T T C C A A G C A A C G T T G C T A C G T T C C T T G G T A G C T T G G A A G C T A C C A A G C A A G C T T G C T T C G T A G C A A G G T A C C T A C G A T C G A T C G A T G C A T C G T T C C A A G G A T C G T T C C T A C G A A G C T T G C T A C G A T G C T T G G A A G G A T C C T A G C T A C C T T C C T A C C T A C C T T G C A A G C T T G C T T G C T A G C A A C G T A G C T T C C T A C G A A C C T A G C T A G C A A G C T A C G T +T C G T T G G T T C C T T C C T A C C T T G G T A G G A A C C T T C C A A C G T T C C T T C C T T G G T T C G A A C C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A T C C A T G G T T C G A T G G T A G C A T C G T A C G T A G G A A C C A T G C T T C G A T G C A A C C T A C G A T G G T T G C T A G C A T C G T A G C A A G G A T C C A T C C A T G G A A G G A A C C A T C G A T C C T A G C A T G C A A G C T A G G T T G C T A C C T A G C A A G C T A C C T A G C T T G C T A G G T T G G T A C C A T G G T T G G T A C C T A G C T A C G A A G G A A G G T A C C A A C G T T G G T A G G A T G G T T G G T T G C A A C C A T G C T A C C A A G G T A C C T A G C A T C G A A G C T T G C A A C G T T C C A T C G T A C G A T G C A T C C T A G C T A C C T A C G T A G G A A G G T T C G T A G G A A G C T T G C T T G G T A G C A T G G A A C G A A G G A A C C A A G G A T C G T A G G A A C C T A C C T A G G A A G G A T G C A A G C A T G G T A C C A T G C T A C G T T G C A T G C A A G C T A G C A T C C A A G G T A C G T T G G A A G C T T G G A A G G A A C G A T C C A A G G T A C C A T C G T A C C A T G G T T C G T T G C T T C G T T G C T A G G A A G G T T G G T T C C T T C G T T G C T A C C A A G C A T G C A A G C T A C C T A G C T A G G T T G C T A C C T A G C A T C G T T C C T A C C T A G G A T G G T T C G T T G C T T G G A T C C T A C C T A G G T A C C T A G C T T G G T A C C T T G C A T G C A T C C T T G G A T G G T A G G A T G C T A C C A T G G A A G G A A C C A T C C A A G C A A C C T T G G T A G C T T C C A T C C A T C G T A C C A A G C A A G C A T G G A A G G T A C C A A G C T A C G T A C C T T C C T A C C A A G G T A G C T T G C T T G C T T C C T A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A T C C T A C G A A G G A A G C T A C G T T G C T T C G A A G C T T C G A T G G A A G C A A C G A T C C T A G G A A C G T A C C T T G C A T C C A T G G A A G G T A G G T A C C A A G C T A C G T A C G A T C C A T C G T A C G A T G C T T G G A A G C T T C G T A G C T A C G T A G G A T G C T A C C T T G G T T G C A A G G T T G C T T G G T A C G T T C G A A G C A T C C A T G G A A C C T T G C A T G G T T G C T A C C T A C G T T G C A A G G A T G G T T C C A T C C A T C G A A G G A A G C T A C C T A G C T A C C T A G G A A C C A T C G T T C C T T G G A T G G A A G G A T G G A A G G T T G G T A G G A T G G T T C C T T G C A T G G T A C C T A G C T T G G T T C G T T G C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T A G G T A G C A T G C A A G C A A G C T T C C A T C G T T G C A A C G A A C C A A G G A T C G A T C G A T G C A T C G A T C G T A G G A T G G T A G C T A C G A T G C T T G C A A C G A T G C T T G G A A C G A T C C T A G C A A C C T A C C T T G C T A C C T T G G A A G C T T G C A T G C T A G C A A C G T A G G A T C C A A G C A T C C T A G C A T G C A A C C T A G G T BAO_266 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 2 1 1 2 2 1 1 2 2 2 2 1 2 1 1 1 1 2 2 2 2 1 2 1 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 1 2 1 2 1 1 1 1 1 2 1 2 2 2 2 1 1 1 2 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1 2 1 1 2 1 2 1 1 2 2 2 2 2 2 2 1 1 2 1 1 1 2 2 1 2 2 2 2 2 1 1 2 1 2 2 2 2 1 1 2 1 1 2 2 2 2 1 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 1 2 2 2 2 1 2 2 1 1 2 1 1 1 2 2 1 2 1 2 1 1 1 2 1 2 1 1 1 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 2 1 2 2 2 2 2 1 1 2 2 1 1 1 1 1 1 2 1 1 1 1 2 2 2 1 1 2 2 2 2 2 2 1 2 2 2 1 2 1 1 2 2 2 1 2 1 2 2 2 1 2 1 2 1 2 1 2 1 2 2 1 2 2 2 2 1 2 2 1 2 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 1 2 2 2 2 2 1 1 2 1 2 2 2 2 2 2 2 2 2 1 2 2 2 2 2 1 1 2 +T G C T A C G T A C G T T G C T A C C T T G G T A G G T A C G T A C C A A G G T T C C T T C C T A G G T T C G A A G C T T G G T A G C T A C C A A G C T T G C T T G G T A G C A T C C A T G G T T C G A T G G T A G C A T C C T A C C T A G C T A C C A T G G A T C G T T G C A A G C T T C C T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C C A T C G A A G G A T C C A T C G A T C G A A G C T A G C A A G C A A G G T A G C T A G C T A C C A A G C T A C C T A G C T T G C T A G G T T G C T A G C T T C C T A G G T A C G T A G C T T G G A A C G A A G G T A C C T A C G A A G G T A G G T T G C T T G C T T G C A T C C A T G C A A C C A A G G A T C C T A G C T T C G A A C G T A G C A A C G T A G G A A C G A A C G A T C C A T C G T A G C T A C G T A C G T A G G A A C G T A G G A A C G T T C C T T G C A T G G T T G C A T G G A A C C A T G G A A C C A A G G A A G G T T C C A A C C T A C C T A G G A A G G A A G C A A G G A T C G A A C C A T G C T A C G T T G C A T G C T A G C T A G C A T C C A A G G T A G C A T G C A A C G T A G G A A G C T T G G T T C G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A T G C T T C C T A G C A A G G T A G C T A C C T A G C A A G G T T C C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A G C T A G G T A G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G A A G G T A G G A A G C T A C C A T C C A A G G T T G C A T C C A A C C A A C C T A G G T A G C T T C C A A G C A T C G T A C C A A C C A T G C T T G C A A G G T A C C A A G C T A C G A A G G T A C C T A C G A A G G T A C C T T G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C T T G G A A C G A A G C T A C C T A C G T A C C A T C C T A C G T T C G A A G C T A C G T T G C T T C G A A C C T A C G A A C G A A G C A A G C A A C C A A G G A T G C T T G C T T G C A T C C A T G G T T C G T A G G T T G C A A G C T T C C T T G G A T C C A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A G G A T G C T A C C A T G G T T G C T T G G T A G C T A G G T A C G T T G G T A C C A T C C A T G G T T C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G A T G G T T C G A T C C T T C C T A G C A A G C T A G C A A C C T T G G T A G G A A C C A T G C T T C C T T G G A T G G T A G G A A G G A T G C A T G G A A G G A A G G A T C C T T G C A T C G T A C G T A G C A A G G T T C G T T G C A A C G T T C G T T G C T A C G T T C C T T G G T T G C T A G C T A G C T A C G A A G G A A G C T T G C T T C G T A G C A A G C A A C C A A G C A T C G A T C G A A G C T T G G T T G C A T G G A T C G A A G C T A C G A T G C T T G C T A C C A T G C T T G G A A G C A T C C T A G C T T C G A A G G T T C C T T C G T T G C A A G C T T G C T T G C T A G C A A C G T A G C T T C C T A C G A A C C T A G C T A G G T A G C A A C G T +T C G T T G G A T G C T A G C A A G G T T G C T A G G T A C G T A G C A A G G T T G C T T G C T T G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C A T G G T A G C A T G C A T G G T T C G A T G G T A G C A T C C T A C C A A G G A T G G A T C G A A C G A T G C A A G C T T C G T T G C T T G C T A G C A T C G T A G C A A G G A T C C A T C C A T G G A A G G A T C G A T C G A T C G T A C G A A G C A A G C T A G G T T G C T A G C T A C C A A G C T A C C T A G C T T G C T A G G T T G C T A G C T T C C A T G C T A C G T T G C T T G G A A C C A A G C T A C C A A C G A A G G T T G G A T G C T T G C T T G C A A C C A T G C A A C C A A G G A T C C A A G C A T C C A A G G T A G C A A C C T A G G A A C G A A C G T T C C A A C G T A C G T T C G T A C G T A G G A A G G T T G G T A G G T T C C T A G C A T G G T A G C T T C G T A C C A A G G T A G C A A G G A A G G T A G C A A G C T A C C T A G G A A G G A A G C A A C C A T G G T A C C A A C C T A C G T T G C A T C C A A G G T A G C T T C C A A G G T A C C A T G G A A G G T A G G A A C G T A G G A T G G T A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G C T A G G T A G G T T G C A T C C T T C C T T G G T A C C A A G C A T G C A A G G A T C C T A G G A A G G T A G G T T C G T A G G A T G G A T G C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A G C T A G G T A C C T T G C T T G G T A C C T T G C A T G C A T C C T T C G T T G C A A C C A T G G T T C C A T C C A A G G T T G C A T C G A A G C A A G C A A G C T T G C T T C C A T C G A A C G A A C G T A G C A A G C A T G G A A G G T A C C T T G C T A C G A A G G T A C G T A C C A A G G T A G C A T C C T T C C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T T C C T A C G T A G C A T C C T A C G T T C G A A C G T A C G A T G C T T C G A T C C T T C G A A G G A A G C A A C G A T C C T T C C T T G C A A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T T C C T A G G A T G G A T C G T A G C A T G C T T G G A T C C T A C G T A G C T A C G A A G G A T G C T A C C A A G C A A C C A T G G T T G C T A G G T A C G T A C C T T G C T A G C A T G C T A C C T T G C A T G G T A C C A A C C T T G C T T G C A A G G A T G C T T C C A T C C A T C G A A G G A A G C T A C C A A C C A T G C T T G C A A C C A T G G T T C C T T G G A T G G T A C G A A C C T A G C A T C G T T C G A A G C T T C C T T G C A A C G T T G G A A G C T A G C A T G G A T G C A A G C T A C G T T G C T A C G T T C C T A G G T T G C T A G C T A G C A A C C A A G G A A G C T T G C A T G G A T G C A A C C A T C C A A C G A T C G A T C G A T G C A T C G T T G C T A G G A A G G A T C G A A C G A T G C T T C C T A G C T T G C T T G G 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G T T C C T A G C A T C G T T C C T A C C A A G G T A G C T T G G A T G C T T G G A T C C T A C C T A G G T A C G T T G C T T C G T A C C A T G C T A C C A T C C T T C G A A G G T A G G A A G C T A C C A T G G A A G G A A C C A T C G A A G C A A G C T T G C A T C C T T C G T A C G A T C G A A C C A A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C A T G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C T T G G T A C G A A G C T T G G T A C G T A G C A A G C T A C G A A G G A T C G T A G G A T G C T T C G A A C C T T C G A A C G A A G C A A G G A T C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G T A G G T A G C A A G C T T C C T A C G A T G G T T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T T G G A T G C T T G C T T G G A T G C A T G G T A G C T A G G T A C G T T C G A A G C A T C C T T G G A A C C A A G C A T C C T A C C A A C C T A C G T T G C A A C G A T G C T A C C A T C C T T C G A A G G A A G C T A G C T A G C T T C C T T G C A A C C A T G C A A G C T A C C A T G G A A G G A A G C A T G C A T G G T A G G A T G G T T C C T T G C A A G G T A G C A A G C T A G G T T G G T T G C A A C G A A C C T T G C T T C G A A C C T A G G T T G C A T C G T A G C T A C C A A G G A A G G A T G C A T C C T T G C A A G C T A C C T A G G A T C C A T C G A A G C T T G G T T G C T A G G A A G G A T C G A A C G A T G C T T C C T A C G T T C C T A G G A A G C T A C C T T C C A A C C A A G G T T G C T T C C T T G G A A G C T T G C A T G C T A G C A A C G T A G C T T G C A A G C A T C C T A G C A T G C A A C C T A G G T BAO_268 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 1 2 2 2 1 2 1 2 2 1 2 1 2 1 2 2 1 2 2 2 1 1 2 1 2 2 2 1 1 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 1 2 2 1 2 1 2 2 1 2 2 2 2 1 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 1 2 1 1 1 1 2 1 1 1 2 1 1 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T T C C T A G C A T G G T A G C A T G G A A C C A T G G A A C C A A G G A T C G A T C G A A C C T A G C T A G G A A G G A A G C A A G C A T G G T A C C A A C C A A C G A A G C A T G C A A G G T A C C T T C C A A G G T A C C T T G G A A C C T A G G T A G G A A G G T T C G A A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G G T A G G A A G G A T C G A T G C T A C C T A G C T A G G T A G G T T C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A G C T A G G T T G C T A G C T T C C T A C C A T G C T A G C A T C C T T C C A T G G T A G C A A G C T A C C A T G G A A G G A A C C A T C C A A G C A A C C T T G G T A G C T T C C A T C C A T C G T A C C T T G C A T G C T T G C A A G G T A C C T T G C T A G C A T C G T A C C T A C C A A G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T T C C T A C G T A C C A T C C T A G G A A G G A A C G T A C C A T G G A T C G A A G C T T C G A A C G T T G C A A C G A T C C A A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T T G C A A G C A A G C T T G G A T C C A T C G T A G C A T G C T T G G A A G C T T C G T A C C T A G C T A G G T T G C T T G C T T G G T T G C A A G G T T G C T T G G T A C G T T C G T A G C A T C C T T G G T A C C A A G C A T C C T A C G A A C C T A C G T T G C A A G G A A G C T A C C A T C C T T C G A T G C A A G C T A G C T A G C T A C C T A G C A A C C A T C G T T C C T T G G T T G C T T G C A A G G A A G G A T C G A A G G T T C G T T C G T T C G T A C G T A G G A A G C T A G G T T G G A T G C A A G C A A C G T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T C C T T G C T T G C A A C C A A C C T A C C T T C G A T C G A T G C A T C G A T C G T A G G A T G G A T C C T A C G A A G G A T C C T A C G A T G C T T G G A A G G A T C C T A G C T A C C A T C C T A C C T T C G T T G C A T G C T T G C A T G C T A G C A A C G T A G C T A C C T A G G A A C C T A G C T A G C A A G C T A C G T +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G A A C C A A G G A T C C T T G C T A C G T T G G A A C C T T G G T A G C T A C C T T G C A A C C T T G G T A G C A A C C A T G G T A C G T T G C T A C C A T C C T A C C T A G G A A C C A T C C T T C G T A G C T A G C T T C G T T G C T T G C T T G C A T C C T A G C A T G C A T C C A T C C A T C G A A G G A T C C A T C G T T C G T A G G A A G C A A G G A A G G T T G C T A G C T A C G A A G C T A C C T A G C A A C G T A G G T T G G T A C C T T C C T T G G T A C G T T G C T T G G A A C G A A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C A T C C A T G C A A C C A A G G A A C G A T G C A T C C T T G G T A G G A A C G T A G G A A C G T A C G A T G C A T C G T A G C T A C G T A C G T A G G A A C G T A G G T A G G T T C C T A G C A T G G T T G C A T G G A A C C A T G G A A G C A A G G A A G G A T C C A A C C T A C C T A G G A A G G A A G C A A C C A T G G T A C C A T G C T A C G T A G C A T G C T A G C T A G C T T C C A A G G T A G C A T G G T A C C T A G G T A G G A A G G T T C G A A G G T A C C A T C G T A C G A T G G T A C C T T G C A T C G T T G C A A G G A A G G T T G G A A G C T T C C T T G G T A C C A A G G A T G C A A G C A T C C T A G C A A C G T A G G T T G C T T G C A T C G T T C C T A C G A A G G T A G C T T C G A T G C T T G G A T C C T A G C T A G C A T G C T T G C T T C C T A C C A T G C T A G C A T C C T T G G T T G C A A C C A T G G A A C C A T G G A A G G A A C C A T C C A A C C A A C C T T G G T A G C T T C G A A C G A A C C T A C G T T C C T A G C A T G G T A G C A A G C T T G C T A G C A A G G T A G G T T C C A A G G T A G C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A T C C T A G G A A C G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C A A C G A T C C T T C C A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A A G G T A G C T A C G T T G G T T G C A T G G T T G C T A G G T A C G T T G G A T G C A A C C T A C C T A C C A A G C A A G C A A C C A A C C T T G C T T G C T A G G A T G C T A C C A T C C T T G G A T G C A A G C T A G G A A G C T T C C T T G C A A C C A A G C T T C C T A C C A T G C T T G C A T G C T A G C T T G G A A G G A T G G T T C C T T G C A A G C T T G C A A G C A T G C T T G G A T G C T A G C A A C C T A G C T A C G A A C C T T G G T A C G T A G G T A G C T A C C A A G G A A G G A T G C A T C G T T G C A A C G A A C C T A G C A T C G A T C G A A G C A A C G T T G C T A G G A A G G A T C G A A C G A T G C T T G C T A C G A T G C T T G G A A G G A T C C T A G C A A C C A A C C T A C C T A C G T T G G A A G C T T G C T T C C T A G C A A C G T A G C A T C C A A G C A T C C T A G G T A G G A A G C T A G C T BAO_274 # subpop. label: 3 (internally 3) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 1 1 1 2 2 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2 1 1 1 2 2 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 1 1 2 1 2 1 1 1 1 2 1 1 1 2 1 2 1 1 1 2 1 1 2 2 1 1 1 2 2 1 2 1 2 2 1 2 1 2 2 2 1 1 1 2 1 2 1 1 2 2 1 2 2 1 2 2 1 1 1 2 2 1 1 2 2 2 1 2 2 2 1 2 1 1 1 2 2 1 2 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 1 1 1 2 1 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 2 2 1 1 2 2 2 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 1 1 2 1 2 2 2 1 1 1 1 1 1 1 1 1 2 2 2 2 1 2 1 2 1 2 2 1 2 2 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 2 2 2 1 1 2 2 2 1 2 1 1 2 2 2 1 2 1 1 2 2 2 2 2 1 2 2 1 1 2 2 1 1 1 1 2 2 1 2 1 1 2 2 1 1 1 2 1 2 1 1 2 2 2 2 1 2 2 2 1 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 1 2 1 1 2 1 1 2 2 1 2 2 2 2 1 2 2 2 1 2 2 2 2 1 2 1 1 2 +T G C T A C G T A C G T T G C T A C C T T C G A A G G T A G C T A C G A A G G A T C C T T G C T A C G T T G G A A G C T T G G T A G C T A C C T T G C A A C C T T G G T A G C A T C C A T G G T T C C T T G C T A G C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A G C T T C C T T G C T T G C T T G C A T C G T A G C A T G G A T C C A T C G A T G G A A G G A A C C A T C G A T C C T A G G A A G G A A G C A A G G A T G C T A G C T A G C A A G C T A C C T T G C T T G C T A G G T T C C T A G C T T C C A A G G T A C C T A G C T T G G A A C G A A G G T A C C A A C G A A G G T T G G T T G C T T G C T T G C T T C C A T G C T A C C A A G G T A C G A A C C T A C C A A C G T T G C A A C G T T C C A T C G A A C G A T G C A T C G T A C G T T C G A A G G T T G G A A C G T T G G T T G G T T C C T A G C A T G G T A G C T T C G T A C C A A G G A A C C A A G G A A G G T T C G A A C C T A C C T A G G T A C G A A G C A T G G A T G G T A C C A T G C T A C G A T G C A T G C T A G C T A G C A T C C A A G G T A C C T T G G T A C C T T G G A A G C A A G G T T C C A A G G T A C C A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A G G T A G G T T G C A T C C T T C C T T G G T A C C A A G C A T G C A A G G A T C C A A C G A A C C T T C G A T G C T A G C A T G G T T G C T A C G A A G G T A G C T T C G T T G C T T G G A T C C T A G C T A G C T A C G T A C C A A G G A A C C A T G G T A G C A T C G T A G G A T G G T A G G A A G C T A C C A T C C A A G G T T G C A T C G A A G C A A G C T T G C T T C C T T C G T A C G A T C G A A C C A T G C A A G C A T G G A A G G T A C C T T G C T A C G T A C G T A C G T A C C A A G G T A G C A T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T A G C A A G C T A G G A A C G A A G C T A C C T T G C T T C G A A C C T T G G A T G G T T G C A A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C A A G C T T G G A T C G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A G G A T G C T A C C A A G C A A C C A T G G T T G C T A G G T A C G T T G G A A C C T A C C T A G G A A C C T T G C A T C C A A C C A A C C T T G C T T G C T A G G A T G G T T C C A T C G A T C G A A C G A A G G T A C C T A G C T T G C T T G C A A C C T T G C A T G G T T G C A T G G T A C G A T G C T A G C A T G G T A G G A T G G A T C C T T C C T A G G T T G G A A G C T A G G T T G G A T G C T T G C A A C G A T G C T A C G A A C C T T G G T T G C T A G G T A G C A T G C A A G G A A G G A T C C A T G G T A G C A A C C A A C C T A G C A T G G A T C G A A G C A T C G T T G C A A G G A T C G A T C G T A C G A T G C T T G C A A C G A T G C T T G G A A G G A A C G T A G C T A C C A A C C T T G C T A C C T T G G A A G C T T G C T T C C T A G C A A C G T A G C T T G C T A G G A A C C T A G C T A G C A A G C T A C G T +T G C T A C G T A C G T T G C T A C C T T C G A A G G T A G C T A C G A A G G A T C C T T G C T A C G T T G G A A G C T T G G T A G C T A C C T T G C A A C C T T G G T A G C A T C C A T G G T T C G T T G C T A C C A T C G T A C C A A G C T A C C A T G G A T C G A T G C A A G C T T C G A T G G T T G C T A G C A T C G T A G C A A G G A T C C T T C G A T C G T A G G A A C C A T C G T T C G T A G C A T G C T A G G A A G G T A G C T A G C T A G G A A C C A T G G T T G C T T G C T A G G T T G G T A C C T T G G A A C G T A C C T A G C T A C G A A G G A A G G T A C C A A C G A T G C T A G G A T G C T T G G T T G C A T C C A T G C A A C C A A G G A A C C T A G C T T C G A A C G T A G G A A C G T A G G A T C G A A C G A T G C A T C G T A C G T T C C T A C G T A G G A A G G T T G G T T G G T T C C T A G C A T G G T A G C T T C G T A C C A A C G T A C C A A G G A A G G A T C C A A C C T A G C T A G G T T G G A T G C A A G C A T G G T A C C A A G C A A C G T T C C A T C C T A G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A G G A A G G A A G G A A C C T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G C T A G G T A G G T T G C T T C C T T C C T T G G T A C C A A G C T T G C A A G G A T C C T A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C C T A G G A A G G T T C G T T G C T T G G A A C C T A G C T A G G T A C C T A G C A A G C T A C C A T G C T A C C A T C C T T G G A T G G T A G G A T G G A A C C A T G G A A G C T A C C A T C G A A G C A A C C T T G G T A G C T T C C A T C C A T C G T A C C T T C C T A G C A T G G T A G C A A G C T T G C T A C G A T C C T T C C T A C C T A G G T A G G T T G C T T G C T T C C A A C C T A G C A T C G A T G C A T C C A T G G T A C G A T G C T A C C T A G G T A G C A A C C T A C G T T C G A T C G T A C C A T G G A T C G A A C C T T C G A T G G A A G C A A C G A T C C T T C C A T G C T T G C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T C G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T A G G A A C G A T G C T A C G T A C G T T G C T A G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T A C C T T G C A T G G T T G C A A C C T T G C T T G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G C T T G G T A G G A A C C A T C G T T C G T T G G A T G G A A G G A T G C A A C C T T G G T A G G A T G G T T C C T T G C A A G G A T G C A T G C T T G C T T G G A T G C A A G C A A C C T A G C T A G G T T C G T T C C T A G C T T C G A A G C T A G G A A G C A A G C T T G C A T G G T T G C A A G C T T C C A A G C A T C G A T C G A A G C T T G G T T G C A A G G A T C G A T C G T A C G A T G C T T C C T A C C A T G C T T G G A A G C T A C C T T C C T T C G A A G G T T C C T T C G T T G G A A G C T T G C T T G C T A G C A A C G T A G C T T G G A A C G T A C C T A G G T A G G T A G C A A C G T BAO_275 # subpop. label: 3 (internally 3) -2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 1 1 2 1 1 1 1 1 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 1 1 1 2 2 1 1 1 1 2 1 1 1 1 1 1 1 1 2 2 1 1 1 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 1 2 1 2 2 1 2 2 1 2 2 2 2 2 2 1 2 1 1 2 1 2 1 2 2 1 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 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G G A T C G A A C C A T G C T A C G T T G C A T G C T A G C T A C C T T C C A A G G T A C G A T G C A A C G T A G G A A G C A A G G T T C G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A T G C T T C C T A G G A A G G T A G G T T C G T A G G A T G G A T G C T A C G A A G G T T G G T T C G A T G C T T G G A T C C T A G C T A G G T A G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G A A G G T A G G A T G C T A C C A T C C A A G G T T G C A T C G A A G C A A G C A A G C T A G C T T C C A T C G A A C C T A C G A T C C A A G C A T G C A A G G T A C C T T G C T A G C A A G G T A C G T A C C A A G G T A C G T T G C T T G C T T G C T A C C T T G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T A G C A T C C T A C G T T C G A A C G T A C G A T G C T T C G A A C C T A G G T A C G T T G C A A G C A A C C A A G G A T G C T T G C T T G C A T C C A T G G T T C G T A G G T T G C A A G C T A C G T A G G A T C C A T C G T A G G A T C G T T C G A A C C T T C G T A C C T A G C T A G G A T G C T A C C A A G C A A C C A T G G T A G C T A G G T A C G T T G G T A C C A T C C A T G G T T C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G A T G C T T C C A T C G A T C G A A G G A A G C T A C C A A C C A T G C T T G C A A C C A T G G T T C C T T G G A T G G T A C G A A C C T T G C A T G G A A G G A A G G A T C C T T G C A T C G T A C G A A G C A T G G T T G G T T G C A A G C T A C C T T G C T A C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G G A T G C A T G G A T G C A A C C A T C C A A C G A T C G A T C G A T G C A T C G T T G C T A G G A A G G A T C G T A C G A T G C T T G C T A C C A T G C T T G G A A G C A T C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G G T T G C T A G C A A C G T A G C T T C C T A C G T T C C T A G G T A G C A A G C T A C G T +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G A A C C A A G G T T C C T T G C A T G G A A G G A A G C T A G G T A C C A T G C T T G C T T G C T T G G T A G C A A C C A T G G T A G G A T G G T A G C A T C C T A C C T A G C T A G C A A G C T T C G T A G C T A G C T T C G T T G C T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A C G A A C C T T C C A T G G T T C G T A G G A A G C A A C G A A G G T T G C T A G C T A C C A A C G T T C C T T G C T T G C T A G G T T G G T A C C T T C C A T G C T A C G T A G C T T G G A A C G A A G G T A C C T A C G A A G G T A G G T T G C T T G C T T G C A T C C A T G C A A C C A A G G A T C C T A G C A T C C A A C G T A G G A A C C T A G G A A C G A A C G A T G C A T C G T A G C T A C C T A C G T A G G A A G G T T G G A A C G T T C C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A A G G T T C G A A C C T A G C T A G G T A C G A T G C A A G C A T G G T A C C A T G C T A C G T A G C A T G C A A G C T A G C A T C C A A G G T A G C T A C C A A C C T A G G T T G C T T C G T T C G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A A G C A T C C A A G C T A G G T T C G A T G C T A G C A T C G T T C C T A C G A A G G T T G C T T G G A A G C T T G G A T C C T A C C T A G G T A C C T T C C A A C C T A C G A T G C T A C C A T C C T T C G A A G G T A G G A T G G T A G C A T G C A A G C T T C C A T C C A A G C A A G C T T C C T T G C T T C C A T C G A A C G A A C G A A G C A A G C A T G G A A G G T A C C T T G C T A C G A T C C T T C C T A C G A A G G T A C C T T G C T T C C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A T C C T A C G T T C G A A G C T A C G T T G C A T C G A A C C T T C G A A C G A A G C A A G G A T C C T A G G A T C G T T C C T T C C T T C C A T G G T T C G T T G G T T G C A A G C T T C C T T G G A T C C A T C G T A G C A T G C T T G G A A G C T T C G T A G C T A C G A A G G A T G C T A C C A A G C A A C C A T G G T A G C T A G G T A C G T T G G A T G C T A G C A T G G T T C C A T G C A T G C T A C C A A C C T T G C T T G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C A A G C T A C C T A G G A A C C A T G C A T G C T T G G T T G G A A G G A A G G A T G G T T C G T A G G A T G G T T C C T T C C T A G C T T G C T A G C A A G G T T C G T T G C A A C G T T C G T T G C T A C G T T C C T T G G T T G C T A G C T A G C A A C C A A G G A A G C T T C C T T C G T T G C A A G C T T C C T A G C A T C G A T C G A T G C A T C G T T G C T A G G A A G G A T C G T A C G A T G C T T G C T A C C A T G C T T G G A A G C A T C C T A C C A A C C A A G G T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C T A G G A A C C T A G C T A G C A A G C T A C G T BAO_276 # subpop. label: 3 (internally 3) -2 2 2 2 1 2 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 1 2 2 1 1 2 2 1 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C A T G C A A C C A A G G A T C C T A C C A T C C A A G G T A G C A A C C T A G G A T C G A A C G T T C C A A C G T A C G T T C G A A G G T A G G A A G G T T G G A A C G T T C C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A A G G T T C C A A C C T A C C T A G G A A G G A A G C A A G G A T C G T A C C A T G C T A C G T T G C A T G C T A G C T A G C T T C C A A G G T A G C T T G G A A C G T A G G A A C G T A G C A A G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C A T C C A T C C T T G G T A C C A A G C A T G C A T G C A T C C T A G G A A G G T A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T C G A T G C T T G G A T C C T A G C T A G G T A G C T A G G A A G G T A C C T T G C A T G C A T C C T T C C T T G G T A G C A T G C A A G C A T C G A A G C T T C C A T C C A A G C A A G C T T C C T T G C T T C C A T C G A A C G A A C G T A G G A A G C A T G G A A G G T A C C T T G C T A C G A T C C T A C C T A C 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A C G A A G C A T G G A T C C A T C C T A G C A A C C A A G G T T C G T A G C A A G G T T G C A A C G A A C G T T G G T T G G T T G C T T G G A T C C T A C C T A G G T A C C T A G G A A G G T A C C T T G C A T G C A T C G T T G G T T G C A A C C A T G G A T C C A T G G A T G G A T C C A T C C A A G C A A C C T T C C T T G C T T C G A T C G A A C C T A C G T T C C T A G C T T G C T A G G T A C C T T G C T A C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C A A G C T T G C A A G G A A G C T A C C T T G C A A C G A A G G T T C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C T T C G A A C C T T G G A T G G T T G C A A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G A A C G T A G G T A G C A A G G T A C C A A G C A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T T C G T A G C T A G C A T G G T T G G A T G C T A G G T T G C T A G G T A C G T T C G T T G C A T C C T A G G A A C C A T C G A A G G T T G C T A C C T T G C T T G C A 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A C C T A G G T A C G T A C C A A G C T A C C T T G C A T G C A T C C T T C C A T G G T A G C A A G C A A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C G A A G G T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T A C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T T G C A A G G A A G C T A C C T T G C A A C G A A G G T T C C T A C G A A C C A T G C T A C G A A G C A A C G T A G G A T G C A T C G A T C C T T C G A T G G T T G C T A C G A A C C T A G G A T G C T T C C T T C G A A C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T C G A T C G T A G G T A G C A T G G A T C C T T G G T A G C T A G G A A G G A T G C T A C C A T G G A A C C T A G G T A G C T A G G T A C G T T G G T A C C T A G C A T G G A A C C A T G C A A G C A A C C A A C C T A C G T T G C A A G G T T G C T T C C A T C C T T C G A A G G A A G G A A G C T A G C T A C G A A G C A A G C A T G C A T G G T T G C A T G G A T G C A A C G A A C G T T G G A A C G A A C G T T G C T T C C A A G C A T G C T A C C T A G C A T C C T T G C A A G C T A C G T A G C T A G G T T C G T T C C T A G C T T C G T A G C T A C C A A G G A A G C T A C C T T C G T T G C A T C C A A C C A A G C A T C G A T C G A T G C A T G C A T G G T A G C A T G C T A G C T A C G A A G C T T C C T A C G T T G C T T G G A T G C T T C C T A G C T A C C A A C C T T C C T T C G T A G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C A A C C T T C C T A G C T A G C A A G C T A C G T BOR_9505 # subpop. label: 4 (internally 4) -1 2 2 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 2 2 1 1 1 1 1 1 1 2 1 1 2 1 2 1 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 1 2 1 2 2 2 1 1 1 1 1 1 2 2 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 2 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 1 1 1 1 2 1 1 1 1 1 1 1 1 2 2 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 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C A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A G C T T G G T A G C T A G C A T G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T C C A T C C A A C G A A C C A A G G T T C C T A G C A A G G A T C C T A C G A A G G A T G C T T G G T T G C A T C G A T C C T A G C T A G G T A C G T T G G A A G G T A G C A T G G T A C C A T C C T T G G T T G G T A G C A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A G C T T C C T A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G G T A C G A T G G T A G G T A G G T A G C A A C C T A C G A A G G A A G C T A G C T T G G A T C G A A C C T T C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A T C G T A G G T T G C A A G C T A C C A A G C A T C G T T C G T A G C A T G C A A C G A T C C T T C G T A C C T T C G T A G C T T G C T A C C T T G G T T G C T A G G T T G C T A G G T A C G T T C G T A G C T A G C A A G G T A C C T T G C A T G G T A C G A A C C T A C G T T G C A T G G A A G C T T C C A T C C T T C G A A G C T T G C T T G C T A G C T T C C T T G C A A C C A T G G T T C C T T G G T T G G A A G G A A C C T A G G A T G G T T C G A T C C A T C C T T C C A A G C T T G C A A G C T A G G T T G G T T G C A A G C T A C G T A G C T T C G T T C C T T G G T T G C T A G G T A G C A T C C A A G G A A G C T A C G A T G G T A G C T A C G A A C C T A C G A T C C A T C C A T G C T T G G A T C G A A G G A T G G A A C C A A C G A A G C T T C C T A C C T T G C T T G C A A G C T A C C T A G C T A C C T A C C T T G C T A C G T T G G A A G C T T G C A T G C T A G C A A C G T A G C A A C G A A G C A A C C T A G C T A G C A A G C T A C G T +A C C T A G G T A C G T T G C T A G C A T G C T A G G T A G G T A G G A A G G T A G G A T G C T A G G T T C G A T C C A T G G T A G C A T G G A T G G T T G C A T G G T A G C T T C C A T G G T T C G T T G C T A C C A T G C T A C C T A C G A A G G A T G C T T C G A T G C A A G C T T C G T T G C T T G C T A G C A T C G T A G C A T C C A T C C A T C G A T G G A T G C T T G C A A G C T T C G T T G G T A G C A A G C A A G G T T G C T A C C T A G C A A G C T A C C T A G C T A C G A A C G T T C C T A G C T T C C A T G G T A C C T A G C T T G G A A G G T A G C T A C C A T C G A T G G T T G G A T G C T T C C A T G C T A C C A T G C A A C C A A G G A T C C T A G C T T C G A A G C T A G G A A C G T T G G A A C G A A C G T T G C A A C G T A G G T A C C A A G G A T C C A T C C T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A T G G T A C G T T G C A T G C A A G G T A G C A T C C A A G G T A G C T T G G T A C G T T G G T T G C T A G C T T C G A T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A T G C A T G G A T C C A T C C T A C G A A G C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T G C T A C C T A G C T T C C A T G C A A G C T A C C T T G C A T C C A T C C T A C G T T C G T A G G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A T C G T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T C C T T G G A A C G A A G C T T C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C C T T C G A T G G T T C C T A G C A A C C A A G G A T C C T A G C T T C C T T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A C C T A C G T A C G T T G C T T G C T T G G A T G C A T C C T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C T T G C A T G G T T G C A A C C T T G C T T G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G C T T G G T A G G A A C C A T G G T T C C T T G C A T C G A A G G A T G C A A C G A T G G T A G G A A C C T T C C T T C C T A G G T T C C A A G C A A G G T T G G A T G C A T G C T A C C T A G C T A C G A A C C T T G G T T G C T A G G T A G C A T C C A A G G A A G C T A C G A T G G T A G C T A C G A A C C T A C G A T C C A T C C A T G C T T G G A T C G A A G G A T G G A A C C A A C G A A G C T T C C T A C C T T G C T A G G A A C C A T C G T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C A A C G T A C C T T G C T A G C T T G C A A C C A A C G T BOR_9506 # subpop. label: 4 (internally 4) -1 2 2 2 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A G C A T G C A A G C A A G C T T C C T T G C T T C G A T C G A A C G A A C C T A G C A A G C A T G G A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C T A C C A A G C T T C C T A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G C T T C C T A G G T T G C A A C C T A G G A A C G T A G C T A C G T T G C T T C G A T C C T T C G T A C G A A G C A A G G A T C C A A G G A T C C T A C C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T T C C T T G G A T C C A A C G T A G G T A G C A T G G A T C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G T T G C T A G G T T G C T A G G T A C G T T G G T A G C T A G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A G G A T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G C T A C C T A G C A A C C A T G G T T C C T A G G A T G G T A G G A A C C A T G C A T G G T A G G A T C C A T C C T T G C A A C G T T G C A A G C T A G G T T G G T T G C A T G C T A C C T A G C T A C G A A C C T T G G T T G C T A G G T A G C A T C C A A G G A A G C T A C G A T C G T T C C T A C C T A C C T T G G A T C C A T C C A T G C A A G C A T G C A A G G A A G G A T C G A A C G A A G C T A G C T A C C A T G C T T G C A T C C T A C C T A G C T A C C T A G G T A G C T T G G T T G C A A G G T T G G T T C C A A G C A A C G T A G C T T C C A A G C A A C C T A G C T A G G T A G C A A C G T BOR_9508 # subpop. label: 4 (internally 4) -1 2 1 2 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 2 2 2 2 2 2 1 2 2 2 2 1 1 1 2 1 1 1 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 1 2 1 1 2 1 2 2 2 1 1 1 2 1 2 2 1 2 1 1 1 1 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 1 2 1 1 2 1 2 2 2 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 1 1 1 2 2 2 2 2 1 1 1 2 2 2 2 1 1 2 1 2 2 1 1 2 2 1 1 1 1 2 1 1 2 1 1 2 2 2 2 2 1 2 2 2 2 2 1 2 1 1 2 2 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 1 2 1 1 2 1 1 2 1 2 2 2 2 2 2 2 1 1 1 2 1 1 1 2 2 1 2 2 1 2 1 2 1 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C T A G C A T C C A T G G T T C G T A G G T T G C A A C C A A G C T T G G A T C G A T C G T A G C A T G C T T G G A A G C T T C G T A C C T A C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T A C G A A G C T A C C T A G G T A C C T T G C A T G C T A C G A A C C T A C G T T G C A A C G A T G C T A C C A T C C A T G G A A G G A A G C T A G C T A G C T A C C T T G G A A C C A A C G T T C C T T G G T T G G T A G G A T G C T T G G A T G C T A G G A A G G T T C G T T C C T A C G T A G G T A G C T A G C T T C G A T G C A A C G T A C G T A G C T T C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A G G A A C C A T C G T T G C A A C C A A C C A A G G A T C G A T C G A A G C T T G G T T G C A T G G A T C G T T C G A A C G A T G C T T G C T A C G A T G C A T G G A A G C A T C C T A G C T A C C A A C C T T C C T A C C T T G C A A G C T T G C T T G C T A G C A A C G T A G C A T C C A A G C A A C G T A G G T A G G T A G C T A C G T +A C C T A G G T A C G T T G C T A G C T T G C T A G G A A C G T A C C A T G G T T C C T T G C T T G G A A C G A A G C T A G G T A G C A T G C A T G C T A G C T T G C T A G C A T G C A T G G T T C C T T G G T A C C A T G C T A C C A A C G A A G G T T G C A A C G T T G C A A C C T T C G A A G G A T G C T A G C A T C G T A G C A A G C A T C C A T C C A T C G T A G G A A C C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A G C T T G C A A G C T A G C T A G G T T G G T A C G T T G G A T G G T A C G A T G C T T G G A A G G T A G G T A C C A A C G A T G C T A C G A A G G T T G G T T G C A T C C A T G C A A C C A A G G A T C C T A G C T T C G A A C C T A G C A A C G T T G G A A G G T A C G T T G C A T C G T T G G T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C A T G G A A G C A A G G A T C G T T C G A A C C T A G C T A G G T T G C A A G C A A G C A T G G T A C C A T G C T A C G T A G C A T G C T A G C T A G C T T G G T A G G T A C C T T G G T A C C T A G C A T G C T T C C T A C G T A G G T A C C A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A G G T A G G T T G C T T C C T A C G T A G G T A G G A A G C T T G C A A C G A A C C A A G C T A G G T T C G A T G C T A G C A T C G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A G C T A G G T T G C T A G C A A G G A A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C G A A G C A A C C T T G G T T C C T A C G T A G C A A C C T A C G T T C C T A G C A T G G T A G G T A C C T T G C T A C G T A C C T T C C T A C C A A G G T A G C A T G C T T G C T T C C A A C C T A G C A T C G A T G C T A C C T T G C A A C C A A G C T A C C A A C C A A G C A T G C T A C G A A G G T A C G T A C C A T G G A T C G A A C C T T C G A A G G T T G C T A G C A A C C T A G G A T C C T T G C T A G C A T C C A T G G T A C G T A G G T T G C A A G C T A G G T A G G A T G G A T C G T A G G A T G C T T G G A A G C T T C C T A G C T A C G A A G 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A G C T T C G T T C C T T G G T A G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G T T G G T A C C T A C C T A C G T A C C A T C G A T G C T T G G A T G C T A G C A T G C T A G C T A C G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T A G C T T G G T T G C A A G C T T G G T T G C T T G C A A C G T A G C T A G G A A G G A A C C T A G C T A G C A A C G T A C C T +A C G T T G G T T C C T A G C T A C C T T C C T A G G T A G C T A C C A A G G T T G C T T G C T T G G A A C G T A G C T A G G T A G C T A C C T T G C T T G C T T G G T A G C A A C C T T G G T T G G T T G C T A C C T T C G T A G G T A G G T A G C A T C C T T C G T T G C T A C C T T C G A T G G T T G C T A G C A T C G T A G C A A G G A T C G T T C C A T G G A A G G A A C G A T G G T T C C T A G G T A G G A T G G A A G G T A C C T A G C T A G C A A C G T T C C T T G C A A C G T A G G T T G G T A G C T A G G T A G G T A G G A T C C T T G G A A C G T A G G T T C C A A C G A A G G T A G G T T G G T T G C T T G C A T C C A T G C A A C C A A G G A T C C T A C C T T C G A A G C T A G G A A G G T A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T A G C T T C C T T C C T A G C A A G C A T C G T A C C T T G G T A C G T T G G T T G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C A T C C T T G G T A G G A A G G T T G G A T C C A A C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A C G A A G G T A G C A A C G A A G C T T C G T T C C T A G C T A G C A A C G T A G C A A G G T A G G T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G C T A G C A T C C A A G C A A C C T T C C T T G C T T C G A A G C T A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G C T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G C A A C C A A G G T A G C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A A G C A T C G A T C G A A C G A T G G A A G C T A G C A A C C T A G G A T G C T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G T T G G T A G G A T G C A T G G T A G C T T C G T A G C T T C G T A G C T T G C T A G G A A C G T T G C A T G G T T G C T T G G T A C G T T G G A T G C A T G C A T G C A A C C A T C G A T C G A A C G T T C C T A G G T A G C A T G G T T G C T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C T T G C A T C C A T C G T T C C T T G G T T G G A A G G A T G C T T G G A T G G T A G G A A C C A T C C T T C G T A C G T A G G A A G C T T G G T T G G T T G C A A G C T A C G T A G C T A G G T T C G T A C C T A G C T T G C A A G C A T C C A A G G A A C C A T C G T T C G T T G C A A C C T A C C T A C G A T C C A T C G A T G C T A G C T T C C A A G G A T G G A T C G T A C G A A G G T T G C A A C C T T G C T T G C A A G C T A C C T A G C T A C G T A G C T A G C T T G G T T G G A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T A G C T A G C T A G C A A C G T A C C T BOR_9510 # subpop. label: 4 (internally 4) -1 2 1 2 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 1 1 1 2 1 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 2 2 2 2 2 2 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 2 2 1 1 1 2 1 1 1 2 1 1 1 1 1 1 2 2 2 2 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 1 2 2 2 2 2 2 2 2 2 1 2 2 2 1 2 1 1 1 2 2 1 2 2 1 2 1 1 1 2 2 2 2 1 1 2 2 2 1 1 1 2 1 1 2 1 1 1 2 2 1 2 1 1 2 2 2 1 1 1 2 2 1 2 1 2 1 1 1 2 2 2 1 2 1 2 1 2 2 1 1 1 2 1 1 2 2 1 2 1 2 1 2 2 1 1 1 1 2 2 2 1 2 2 2 1 1 2 2 1 2 2 2 2 2 2 2 1 1 2 1 2 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G T A G G T A C G T T G C T A C C T T G C T A G G T A G C T A C G A A G G A T C C T T G C T T G G A T C G T A G C T T G G T A G C A T C C A A C C T A G C T T G C T A G C A T G C A T G G T A G G A T G G T A C C A T G C T A C C A A C G A A G G T T G G A A C C T A G C T A G C T T C C T T G G T T G C T A G C A T C G T A G C A A G C A T C C A T C C A T C G A T G C T A C G T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T G C T A G C T A G G T A G G T T C G T A C C T T G G A T G C T A C G T A G G A T G G A A C G A A G G T T C C T A C G A A G G T T G G A T G C T T G G T T G C A T C C A T G C A A C C A A G G A T C C T A C C T A C G T A C C T A G C T A C G T T G G A A G G T T G G A T G C A A C G T A G C A A C G T A C G T A G G A A C G T T C G A A G G A A G C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A T C G A T G G A A C C T A G C T A G G T T G G A A G C A A G G A T C G T A C C A A C C A A G G T T G G A A C C T A G C A T G C A T C C A A G G T A C G T T G G A A G C T A G C A T G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G C A A G C A T C C T A G G A A G C A A G G T T C C T A G C A T C G T T C C T A C C A A G G T T G G T T C G T T G C T T C G A T C C T T G C T A G G T A C C T T G C A A G C T A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A C G A T C C A T C C A A G C A A G C T T C C T T G C T T C C A T C G A A C G A A C C T A G C A A G C A T G G A A G C A A G C T T G C T A C C A T C C T T C C T T C C A A G G T A C C T A C C A A G C T T C C T A C C T T G C A T G C A T G C T A G C A T G G T A C G A T G G T T C C T A C G T T G C A A G C T T C G A A G C A A G G T A C C A T G C A A C G A T C C T A C G A T G G T T G C T A G C A A C C T T C C T T G C A A C C T A G C A T C C A T G G T A G G T A G G T A G C A A G C T T C G T A G G A T G G T T C G T A G C A T G C T T G G A T C C T T C G T A G C T A G G A A G G A A G C T A G C T A G G T T G C T A G G T A G C T A G G T A C G T T G G A T G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T T G C T T G C T A G G A T G C T T C C A T C G A T C G A A G G A A G C T A C C A A G G T A C C T T G C A A C C A T G C A A G G T T G C A T G C A A C G A T G C A T G G T T C G T A G C A A G G A T C C T T C C T A G G T T G C T A G C T T G C T T G G A T C C A A G C T A C C T A G G T T C G T T C C T T G G T A G C T T C G T A G C A T G C A A G G A A G C T A C C A T G C A A G C A A C C T A C C T A C C A T C G A T C G A T G C A T C C A T G C T A G G A A G C T A C C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C T A C C T T G C T A C G T T G G A A G C T T G G T T C C A A G C T A C G A A G C A A G C A A G C A A C C T A G C T A G G T A G C A A C G T +A C C T A G G T A C G T T G C T A G C T T G C T A G G A A C G T A C C A A G G T T G C T T G C T T G G A A C G A A G C T A G G T A G C A T C C A T C C T T G C T T G G T A G C A T G C A T G G T A C G T T G C T T C C T T G C T A C C T A C G A A C C A T G C A A C G T T G C A A C C T T C G A A G G A T G C T A C C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A C C T A G C T T G G T A G G A A G C A A G C A T C G A T G C T A C C T A G C T A G C T T G C T A G C T A G C T A G G T T G G T A G G T T G G A T G G T A C G A T G C T T G G A A G G T A G G T A C C A A C G A T G C T A C G A A G C T T G G T T G C A T C C A T G C A A C C T A G G T T C G A T G C A T C G A A C C T A G C A A C G T A G G A A C G A A C G T T G C A A G C T T G G T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C A T G G A A G C A A G G A T G G T A G C A A G C T A G C T A G G T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A G C T T G G A A G G T A C G T A C G T A C G T A G G A A G G T T C G T A G G T T C C T A G G A A G G T T G C A A C C A A G G T T G C A A C G T T G G A A G G T A C C T T G C T T C C T T C G T T G G T A C C A A G C T A G G A T G C A T C C A A C G A A G C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G T T C C T A C C A T G G T A G C A T C C T T G G T T G G T A G C A T G C A A C G A T G C A A G C T A G C A T G C A A G C A A G C T T G C T T G G T T C G A T G C A A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G C T T C G A A G C T T C C T A C C T A G G T A C G T T G C T T G C T T C C A A C C T T G C A T C G A T G C T T G G T T C G T A C G A T G G T A C C T A G G T T G C A A C C T A C G T T C G A A C G T A C C A T G C T T C G A A C C T A C G A A C G T T G C A A C G A T C C T T C C T T G C A A C C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G G A A C G A T C C T A G G A T G C A A G G A T C C T T C G T A C C T A G C T T G G A T G C T T G G T T G G A T G C A T G G T T G C T A G G T A C G T A G G A A G C T A G C A T G C T A C C T T G C A T C G A A C G A A C C T A C G T T G C A A G G T T G C T A C G A T C C T T C G A A G C A A G C T A G C A A G C T T G G T A G G A A C C A T G G T T C C T A G G A T G G A T G C A A C G A A C G T T C G T A G G A A C G T A C C T T C C A A G C A T C C T A G C T A G C A T G G A A G C A T G C T A C C T A G C T A G G T T C G T A C C T A G G T T G C T A G C T A G G A A G C T A G C T T C C A T C G A A G C A A C C T A C C A A G C A T C G A T C G A T G C A T C G A T G C T A G C A T G G A T C C T A C G A A G C T T G C T A C G T A G C T T G C A A G G T T C C A T C C T A C G T A G C T A G C T A G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T A G G A A C G T A C C T A G C T A G C A A C G T A C C T BOR_9511 # subpop. label: 4 (internally 4) -1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 1 1 2 1 1 1 2 1 2 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 2 1 1 1 2 2 1 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 1 2 1 1 1 2 1 2 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 2 1 2 2 2 2 1 2 2 1 2 1 1 2 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T C C A T C C A A G C T A G G T T C C A A G G A T G G A A C C A A G G T A G C A A C C T A C G A T G C T T C G A A G C T A C C T A G C T A C G T A G G T A G C T A G G T T G C A A G C T T G G T T G C T T G C T A C C T A G G T T G C A A C C T A G C T A G C T A G C A A C G T A C C T +A G C T A G G A T G C T A G C T A C C T T C G A A G G A A G G T A C G A A G G T T G G T T G C T T G G T T C G A A G C A T G G T A G C A T G C T T G C T T G C A T G G T T G C A T C C T T C G A A C G T T G C T T C C A T G C T A C C A A C C A A G G T T G C A A C G T T G C A A G C T T C G T A G G T T G C T A C C A T C C T A G C A A G G A T C C A T C C A T C G A A G C T T G C T A G C T T G G T A G C T T G C A A G C A A G G T T G C T A G C T A G C A A C C T T G C T A G G T A G C T A G C T T C G T A C G T T G G A A G G T A G G A T G C T T G G A A C G A A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C T A C C A T C C T A C G A A C G T T G G T A C G T A C C T A C G T A C C A A G C T A G G A A C G T A C G A T G C T A G C A T G G A A C C A A G G T T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T G C A A C C T A G C A A C C A T C G T A C C T T G G T A G C T T G G A A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C A T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G C A A G C A A C C T A G G A A G C T A G G T A C C T A G C A T G C T T G C T A C G A A G G T A G C A T G G T A G C A T C G A T C C T A G C T A G C T A C C A A C C A A G C T A G G T T G C T T G C A T C C T A G C T T G C A A G C A T G G T A C C A T G G A T C G A T C C A T G C A A C C A A G C T T C C T A G G T T C G A A G C T A C G A A C G T A G C T A G C T T G C T A G C A A C C T T C G T A C G A T C C T A C C T T C C A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C A T C C T T G G A T C G A A G C T T C C T A C G T A G C A A G C T A C G T T C G A A G G T A C C A T G C T T C G A A C C T T C G A T G C T T G C T A C G A A C C T A G G A T G C T T C C T T C G A A C C T A G G T A C G T A G G T A G C A A G G T A C C A A G C A T G G A T C G T A G G A T G C T A G G A T C C T T C G T A C C T A C G T A G G A T G C A T G G T T G G A T G C A T C C T A G C T T G G T A C G T T G G A T G C A T G C T A C G A A C C T T G C A T C C T A C C T A C C T T G C T T G C A T G G A T G C T A C C A T C C T T C G A A G G A A G C T A G C A A G G T A C C T T G G A A C C A A C G T T C C T T G G A T G G T A C G A A C C T A C C T T G G A T C G A A C G T T C C T T C C T A G C A T G C T A G C A T G G T T G G T T C C A A G C A A C G T T G C T A C G T T C C T T G G T A G C T T G G T A G C T A C C A A G G A A G C T A C C A T C C A A G C T T C C A A C C A A G C A T C G A T C G A A G C A T C G A T G C T A G G A A G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C A T C C T A G C T A C C T A C C T A G C T A C C T T G C A A G C T T G G T T C C T A G G A A C G T A G C A A G G A A C G T A C C T A G C T A G G T A G C T A C G T BOR_9512 # subpop. label: 4 (internally 4) -1 2 1 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 2 1 1 2 2 2 2 1 1 2 1 2 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 1 1 1 1 2 1 1 2 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 1 2 1 1 2 1 1 2 1 2 2 2 2 2 2 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 2 2 1 2 2 2 2 1 1 1 1 1 2 1 2 2 2 1 2 2 1 2 2 2 1 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 1 1 2 2 2 2 2 1 2 1 1 2 2 2 1 2 1 2 1 2 2 2 2 2 1 2 1 1 1 2 2 2 2 1 1 2 2 2 1 1 1 2 1 1 2 1 1 1 2 2 2 2 1 1 2 1 2 1 1 1 2 2 1 2 1 2 1 1 1 2 2 2 1 2 1 2 1 2 2 2 1 1 2 1 1 2 2 1 2 1 2 1 2 2 1 1 1 1 2 2 1 1 2 2 2 1 1 2 2 1 2 2 2 2 2 2 2 1 1 2 2 2 1 1 2 1 1 2 1 2 1 1 1 2 2 1 2 1 1 2 2 2 2 1 2 1 1 2 2 1 1 2 2 2 1 1 2 1 1 2 1 1 1 1 2 2 1 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 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C T T C G A T C G A A C G A T C C T T G C T T G C T A G G A T G C T A C C A T C C A T C G A A C G A A G C T A C C A A G G T T G G T A G G A A C C A T G C A A G C T A G G A T G G A A G G A T G C A T G G T T C G T A G G T T C C A T C C T T C C T A G C A T G C T A G C T T G C T T C G T T G G A T G C T A C C T A G C T A G G A A C C T T G G T A G C T T C G T A G C A T G C A A G G A A G C A T G C A T G C A A G C A A C C T A C C T A C C A T C G A T C G A T G C T T G G A T G C T A G C A T G C T A C C T A C G A A G C T T G C T A C G T A G C T T G G T T G C A T C C T T C C T A C G T A G C T T G C T T G G T T G G T A G G T T G C T T G C T A G C A A C G A A G C A A C C A A G C A A C C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C C A A G G T T C C T T G C T A G G A T C G T A G C T T G G T A G C A T C C A T C C T T G C T T G G T A G C A T G C A T G G T A C G T T G C T T C C T T G C T A C C T A G G A A C C A T C C A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A T C C T T C C A T G G A T G C T A C C A A G C T T G G T A G C A T G C A A G C A A G G T T G C T A C C T A G C A A C G A T G C T A G C T A G G T A G G T T G G T T G C T T G G T A G G T A G G A A G C T T G G A A C G A A G G T T C C T A C G A T G C T A G G A A G G T T G G T T G C A A G C A T C C T A C G A A C G T A G G T A C C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C G A T G C T T C C T T C C A T C G T T C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A A C C A A C G T A G C T T C C T A G G T A G C A T C C A A C G T A C C T T G G T A G C T T G G T A G C T A G C T A C C T T G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G G A T G C A T C C A A G G T A G G T T C G A T G C T A G C A T G C A T G C T T G G A A G G T T G C A T C G T A C C T T C G A T C C T A G C T A G C T A C C T A G G A A G C T A C C A T G G T A G C A T C C T T G G T T G G T A G C A A G C T A C C A T G C A A G C T A G C A T G C A A G C A A G C T T C C T T G C T T C G A T C G A A C G A A C C T A C G A A G C A T G G A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C T A C C A A G C T T C C T A C C T T G C A T G C A T G C T A G C A T G G T A C G A T G G T T C C T A C G T A G C A A C C T A C G A A G G A A C G T A C G A T G C A A C G A T C C T A C G A T G G T T G C A A C G A T C C T T C C T T G C A A C C T A G C A T C C A T G G T A G G T A G G A A G C A A C C T A C C T A C G A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T T C G T A G C T A G C T A G C T T G G A T G C T A G G T T G C T A G G T A C G T T G G A T G C T A G C T T G G A A C C A T C G A T C G A A C G A T C C T A G G T A G C T A C G T A C C T A C C A T C C T T C G A T G G A A G G A A C C T A G C T T G C A A G C A A C C A T G C A A G C A T C C A T G C A A C G A T G C A A C G T T G G A A G C A A C G T A C C T T C C A A G C A T C C T A G C T A G G T T G G A T C C A A G C T A C G T A G C T A G G T T C G T A C C T A G C T T G C T A G C T A G G A A G G A A G C T A C C A T C G T T G C A A C C T A C G T A C G A T C C A T C G A T C C A T C G A T G C T A G G A T G G A A C C T A C G A T G C T T G C T A C G A T G C T T G G A A G C T A C G A T C G T A C C A A C C T T C C T A G G T T G C A A G C T T G G T T G C T T G C T A C C T A G C A A G C A A C C T A G C T A G C T A G C A A C G T A C C T BOR_9513 # subpop. label: 4 (internally 4) -2 1 2 2 2 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 1 2 1 2 2 2 1 1 2 2 1 2 1 2 1 1 1 1 1 2 2 1 2 2 1 2 2 2 2 1 1 1 1 1 1 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 1 1 2 1 2 2 2 2 1 1 2 2 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 1 2 1 2 2 1 1 1 2 1 1 1 2 1 2 1 2 2 1 1 2 1 1 1 2 2 1 1 2 1 1 2 2 2 2 2 1 1 2 1 2 1 1 1 2 2 1 1 2 1 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A G C T A C C T A G G T T C C T A C C T T G C A T G C T T G C T T C C T A G C T A C G T A G C T T G G T A C C T T C C T A G C T A G C A A C G T A C C T +A C C A A G G T A C G T T G C T A G C T T G C T A G C T A C G T A G G A A G G T T G C T T G C T T G G T T G G A A G C T A G G T A G C A T G C T T C C T T G C T T G G T A G C A A C C T T G G T A C C T T G C T A C C A T C C T A G C A A G G A A C C A T C C T A C G A T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T G C A T C C A T C C A T C G A A G C T A C C A A G C T T G G T A G C T T G C A A G C A A G G T T G C T A G C T A G G A A C G T A C C T A G C T A C G T A G C T T G G T A G C T A G G A T G G T A C G T A G C T T G G A A C G A A G G T A C C A A C G A A G G T T G G A T G C T T G G T T G C A A C C A T G C A A C C T A G G T A G G T A C G T A C C T A C G A T G G A A C G T A C C T A G G T T C C A T G C A T G C A A C C T T C G T A C G T A G G A A G G T T G G T A C G T A C C T A G C A T G G T A G C T T C G T A C C T A C G T A G C A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T A G G A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A C C T A G G A A G C A A G C A A C C T T G G T A G C A A G G T T C G A T G G T A C C T T G C T T G G T T G G A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T T C G T A C C A T C C T A C G A A G C A A G C T A C C T A G C A A G G T T C G A A C G A A G G T T G C T T C G A T G C T T G G A T C C T A C C T A G C A T G C T T C C A A G C T A C C A T G C T A C C A T C G T T G C A T G G T A G C A A C G A A C C A T G C A T C G A T C C A T C C A A G G A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C T A G C T T G C T A G C A A C C A A G C T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A T G C A A G C T A C C T T G G T A C G A T G G T A C C T A C G T A G C A A G C T A G G A A G G A T C G T A C C A T G G A T C G A A C C T T C C A T G G T T G C T A G G A T C C T A G G A T C C T A C C T A G C A T C C A T G G A A C G T A G G T A G C A A G G T A C C T A C G A T G G T T G C T A G G A T G C T A C G A T C C T T C G T A C C T A C G T A G C T T G C T T G G T T G G T T G C A T G G T A G G A A G G A A C G T T G G A T G C T A G C A A G G A A C C T T C G A T C G A A C C T T C C T A G G T A G C T T C G A A C C T A C C A T C C T T C G A A C G A A G C T T C C A A G C T T G C A A G C A A C C A T G C A A G C A T C C A T G G A A G G A T G C A T G G T T G G T A G G A T C G A T C C T T G C A A C G T A G G A A G C T A G G T T G G T T C C A A G C T A C G T A G C T T C G T T C C T T G G T T G C T T G C A A G C T T G G A A G G A A G C T A C C T T C G A A G C A A C C T A C C T A C C A T C C A T C G A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G C A A C C T A C G T A G C T T G G A A G C T A C C T T C C T A C C A A C C T T G C T T G G T T G C A A G C T T G G T T C C T A G G A A C G T A G C A A C C A A G C T A C C T A G C T A G G T A G C A A C G T 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G T T G C A T G C A A C G T T G C T T C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G G T T G C A T C G A T G C T A G G T T C C T A C G A T C G A T C G A T G C T A G C T T C C T A G C A T G G T T C G A A C G A A G C T T C C T A G C A T G C T T G G A A G G T A C C A T G C T A C C A A C G T A C C T A C G T T G G A A G C T T G C T T G C T A G C A A C G T A G C T T G G A A C G T T C C T A G C T A G C A A G C T A C G T BOR_9515 # subpop. label: 4 (internally 4) -2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 2 1 1 2 2 1 1 2 2 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 1 2 2 1 1 2 1 1 2 1 2 1 1 1 2 1 1 2 1 1 1 1 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 1 2 1 1 2 1 1 2 1 1 2 2 2 2 2 2 1 1 1 2 2 2 2 2 1 1 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 1 1 1 1 2 1 1 2 2 2 2 2 2 2 2 1 2 1 2 2 1 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 2 2 2 2 1 1 2 2 2 2 1 1 2 2 2 2 2 2 2 2 1 1 1 2 1 2 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T C G T A C C A A G G A A G C A A G G A T C G A T C G A A C C T A G C T A G G T T G G A A G C A A G G A T G G T A C C A A C C T A C G T T G C A T C C A A G C T A G C A T C C A A G G T A G G A T G G A A G C T A G G A A C C A A G C A T C G A A G G T A C C A A G C T T C G A T G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G T A C C A T C C A A G G A A C C A A G G T T C C T A G C A A G G A T C C T A C G A A G G A T G C T T G G T A C C A A G G A T C C T A G C T A G G T A G C T T G G A A G C T A C C A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A G G T A G C T A G G T T C G A T G C T T C G A A C G T T G G A A G C T T G C T A G C A T C C A A G C T A C G A A C C T T C C T A C C A A G G T A C C A A G C T T G C T T C C A A G C T A G C A A G G A A G C T A C C T T G C A A C G A A G C T T C C T A C G T A G C A A C C T A C G A A G C T A G G T A C C A T G C A T C G A A C C T T C G A T G C T T G C T A G G T A G C A A G G A A C G T A C C T A G C A T C C A T G G T A C G T A G G T T G C A A G C T T C G T A C G A T G G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A A C C T T C C T A C C T A G G T A C G T A C C T A C C T A C C A A C C T A C C T T G C A T C C T A C G A A C C T T G C T T G C T A G G T T G C T T C C A T C C A T G G A A G G A A G C T T C C T A G C T T G C T T G C A A C C A T C G T T C C T T G G A T G G T A C G A T G G A A C C A T G G T A G G A A C G T A C G T T C C T A G C A T C C T A C C T A G C T T C G T T G G A T G C A A C G T T G C T T C G T T C C T T G G T A G C T T C G A A G C A T G C A A G G A A G C T T G C A T C G T T G C T A G G T T C C T A C G A T C G A T C G A A G C T A G C T T C C T A G C A T G G T T C G A A C G A A G C T T G C T A C C A T G C T A G G A A G G T A C C T A G C T A C C A A G C T T G C T A C G T T G G A A G C T T G C T T C C T A G C A A C C T A G G T T G C T A G G T T C C T A G C T A G C A A C G T A C C T +A C G T A C G T A C C T A G C T A C C T T C G A A G G T A G G T A C C A A G G T T G C T T G C T T G G A A C G A A G C T A G G T A C C A T G C A T C G T A C C T T G G T T C C A A C C T T G G T T C G T T G C T A G C A T G C T A C G T A C G A A G G T T G C T T C G A T G C A A G C T T C C A A G G T T G C T T C G A T C C T A G C A A G G A T C C T T C C A A C G A A G C T A G C T A G C T T G G T A C C T T G C A A G C A A G G A T G C A A G C T A G C A A C C T A C C T A G C T A G G A A G C T T C C T A G C T A G G A T G G T A C G T T C C T T G G A A C G A A G G T A C C A A C G A A G C T A G G A T G G T T G C T T G C A A C C A T G C A A C G A A G G T A G G T A G G T A C C T A C G A T G G A A G C T A G G A A C G A A C G A T C C A T C G T A C G T T C G T A C G T A G C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G T A C C A A G C A T G G T A G C A A G C T A G C T A G G T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A G C T A G G A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T G C A T C C T A C G A A G C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T C C A T G G A T C C T A G C T A G C T A C C T A G G A A G G A A C C T A G C A T G C A T C G T T C C A A G G T A C C A T G G T A C C A T G G A A G C T A G C A T C C A A G G A A C C T A C C T T G C T T C C A T C G T A C G A T C G T A G C T A G C T T G C T A G C A A C C A T G C T T C G A A C G T A C C T T C C A A G G T A C C T A C C A A G C T T C C T A C C T T G C A T G C A A G C T T C C A T G G T A C G A T G C T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A C C A T C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G T A C G A T G C T A C G T T G G T T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A C G T A G G T A C C A T C C T T G G A A C G A A G C T A G C T A G C T T G C T T G C A A C C T T G C T A G G T T G G T T G G T A G G A A C G A A G G T T C G T A G G A A C G T T C G T T C C T A G C A T C G A A C C T A G C A T C C T T G G T A G C T A C C T A G C T A G G A A C C T A G G T T G C A T G C A A G C T A G C A A G C A A G C T T C C A T C G T T C C T A G C T A C C T A G C A T C G A T C G A T G C A A G C A T G C A A G G A T G G A T C G A A C G A T G C T T G C A A G C T A G C T T G G T T G C A T C C T A G C T A C C A A C C T T C C T T C C T T G C A T G C T T G C A T G C T A G C A A C G T A G C T T G G T A G G A T C C T A G C T A G C A A G C T A C G T BOR_9516 # subpop. label: 4 (internally 4) -1 2 1 2 1 2 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 1 2 1 1 2 1 1 1 2 2 1 2 1 2 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G T A G C A T G C A A G C A A G G A T G C T A G C T A C G A A C C T T C C T T G C T T G C T A G G T T C C T A G C T T C C T A C G T A C C A T G C T T G G A A C C A A G G T A C C T A C G A A G G T T G G A T G C T T G G T T G C A A C C A T G C T A C G A A G G T T G G T A C G A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A G C T A C C T T C C A A G G A T C C A T C G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T T G C A T G C T A G C T A G C A T C C A A G G T A C C T T G G A A G C T T G G A T G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T G C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C T T C G A T C C T A G C T A G G T T G C T A G C T T C G T A C C T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A C C A A G C T T G C A T G G T T C G A A G C T A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T A C C T A G C T A G C A A G C T A C G A A C G A A C G A A C C T T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A C C T A G C A A C C T A C C T A C C A T C G A T C G T A G C A T G C T T G G A T C C T T C G A A C C T A C G T A G G A T G C A T G G T T G G A A C C T A G G T T G C T T G G T A C G T T C G A T G C A T G C T A G G A A C C T T G G A T C G A A C G A T C C T A G G T A G C T T C G A A C C T A C C A T C C T T C G A T G G A A G G A A C C T A G C T T C C T T G G A A C G A T C G T T C C T T G G A T G G A A G G A A G G A T G C A T C G T A G G A A G G T T C C T T G C A A C G T T G G A A G C A T G C T T G G A T C C A A G C A A C G T T G C T T C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G A A G C A A C C T A C C T T C C T T C C A T C G A T G C A T G C A T G C T A G C A T G G T T C G A A C G A T G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C G A A G G T A G C T T G G T T G C A A G G T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +T G G T A C G T A C G T A G C T A C C T T C G A A G G A A C G A A C C A A G G T T C C T T G C T T G G A A G G A A G C T A G G T A G C A T G C T T G C A A C C T T G C T A G C A T C C A T G G T A C G A T G G T A G C A T C C T A C C A A G G A A C C A T G C A A C G T T G C A A G C T T C C A A G G T T G C T T C C A A C C T A G C A T G C A T G C T T C C T T C G T A G G A T C C A T G G T T C G T A G G A A C C A A C G A A G G T A G C T A G C T A C G A A C C T T C C T T G C T T G C T A G G T T C C T A G C T T C C T A C G T A C C T A G C T A C G A A C C A A G G T T C C A A C G A A G G T A G G T T G C T T G C T T G C A T C C A T G C T A C G A A C G T T G G T A C C A T C G T T G G T A G G A A C G T A G G A A C G A A C G A T G C A A C G T A G G A A C C A A G G A T C C T T C G T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C G A A G G T A G C T T G G A A G G T A C G A T G G A A G C T T G G T T G C T A G C T T C G A A G G T A C C A A G C T T C C A T G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T C G T A G C A T G G A T G C T A C C T A G C T T G C T A G G A A G G A A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T G G A T C C A A G C A A C C T T C C T T G C T T C C A T C C A A C G A A C G T T G G A A G C T T G C A A G C A A G C T T G C T A C G A T G G T A C C T A C C A A G G T A G C A A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A C C T A C G T A C C A A G C T A C G A A G C T A G G T A C C T T G C T T C G A A C C T T C G A A C G A A G C A A C G A T C C T A G G A T C G T T C C T T G C A T C C A T G G A A C G T A G G T A G C A A G C T A C C T A C C A T G G A T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T A G G A T G C T A C G A A G G T T G C A T G G T T G C T A G G A A C G T T C G T A G C A T G C T A C G A A C C T T G C A T C C T A C C A T C C T A G G A A C C T A G G T A C G T T C C A T C C A T C G A A C G A A G G T A G C T T G C T T C C A T G C A A G C A T G C A T G G T T G C A A G G T A G G A A G C A T G G T T C G A A G C A A C C A T C G T T C C A A G C A T G C A A G C A T G G T T G G A T C C A A G C A A C G T T G C T A C G A A C C T A G G T T C C T A G G T A G C T A G G A A G G A A C C T A C C A T C C A A G C A A G C A T C C T A G C A T C C A T C C A T G C T T G G A T G C T A G C A T G C T A G C T A C G A A G G A T G C T A C C T T C C T T G G T A C C A T C C T T C C T A C C A T C C T T G C T A C C T T G C A T G C T T G C T T C C T A G G A A C G T A G C T T G G T A C C T T C C T A G C T A G C A A C G T A C C T BOR_9517 # subpop. label: 4 (internally 4) -2 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 1 2 1 1 1 2 2 1 1 1 2 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 2 2 1 2 1 2 2 1 1 2 1 2 1 1 1 2 1 2 1 1 2 1 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 2 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 1 2 2 2 2 2 1 1 2 2 2 2 2 1 2 1 1 2 1 1 1 2 2 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 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2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 +A C C T A G G T A C G T T G C T A G C A A G C T A G C T A G C T A C G A A C G A A G G A T G C A A G C T T C G A T C C A T G G T A G C A T C G A T G C T A C C T T G G T A G C T T G C A T G G T T C C T A G C T T C C A T G C T A C C A A G G A A C C A T C C A A C G T T G C A A G C T T C C A A G G T T G C T A C G A T C C T A G C A A G G A T C C T T C C A A C G A A G C T A C C T A G G A T C G T A G C T T G C A A G C A A G G T T G C A A G C T A G C T A G C A T G C T A G C T A G G T A G G T T G G T A G G T T G G A A G C T A C G T A G C T T G G A A C G A A G C T A C C A A C G A T G C T A G G A T G C T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C G T A C G T A C G T A C C A A C G T A G G A A C G T A C G T T C C A A C G T A G G T T C G A A C G A T C G A A C C T T G G T T G G T T C C T A G C A T G G T A G C A T G G A A C C A T G G A A C C A A G G A A G G T T C G A A G C T A G C T A G G A A G G A A G C A A C C A T C G T A C C A A C C T T C G T A G C A T C C A A G G T A G C T T C C A A G G T A C G T T G G T A C C T T G G A A G G A A G C A T G G A A G G T A C C A T C G T T C G A T G G T A C C T T G C T T C G T T G C A A G G T A G G T T G C T T C C T T C G T T G C T A C C A A G C T A G C A A G C A A C C A A C G A A C C A A G G T T C C T A G C A A G G T T G C T A C C T A G G A A G C A A C G A T G G T T G G A T C C T A G C T A G C T A C C A A G C A A G C T A C C A T G C T A G C A T C G T T G C A T G G T A G C A A G C A A C G A T G G A A G G T T C C A T C C A A G C A A C C T T G C T T G C T T C G A A G C A A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C G T T C C A A G G T A C C A A G C T T C C A T G C A A C C T T G C A T C G A A G C T A C C T T G G A A C G A A G C T A C C T A C C A A C C A T G C T T C G A A G C T A C G T A C C A T G C A T C G A T C C T A G G T A C G T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G G T A C C A A C C A T C G A T C G T A G C A T G C T T C G A A C C T T C G T A C C T A C G T A G G A T G G T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C G T A G C T A G C A A G G T A C C T T G C A A G C A A C C A A C C T T G C T T G C A A G G A T G G T T C C A T C C A T C G A A C G A A G C T A C C A A G C T T C C A T G C A A C C A T G C A T G G T T G C A T G G T A G G A T G C A T G C A T G G A A G C A A C C A T C C T T C C T A C G T A C C T A C C T A G G T T G G A T C G A A G C T A C C T A G C T A C G T T C C T T G G T A G G T T G C A A G C T T G C A A G C A A G C T T C C A T C G A T G C T A C G A T C C A A G C A T C G A T C G A T G C T T G G A T G C T A C G A T G C T A G C T A C G A A G G A T G C T A C C T T G C T T C G A A G G T A C C A T G C T A C C A T C C T T G C T A C G T T G C A A G C T T G G T T C C T A G C A A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T T G C T A G C A T G C T A G C T A G G T A C C A A G G T T G C T T G C T A G G A A G G A A G C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A C C A T G G T T C G T T G C T A C C A T G C T A C C A A C G A A G C T T G C A A C G T T G C A A C C T A C G T A G G T T G C T A C C A T G C T A G C A A G G A T C C T T C C A T G G A T G C T A C C A A G G T T G G T A G C A T G G T T G C A A G G A T G C T A G C T A G C T A G C T T C C T A G G T A G C T A G G T T G G T T G C T T G G T A C G T A C G A T G C T T C C A T G G A A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A T C C A T G C A A C C A A G G A T C C T A G C A A C C T A C G T A C C A A G C T A G G A A C G A A C G A T C C A T C G T A G G A A C G A A G G T T C C A A C C A T G G T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A C C T A G G T A C C A A G C T T C C A T G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A G C A T C C T T C C T A C G A A G C A A G G T T C C T A G C A T C G A T G C T A G G A A G G T A G C A T C G A T G G T T G G A T C C T A C C T A G G T A C G T A G G A A G G T A G G T T G C A T G C A T C C T T G G T T G G T A G G A A G C T A C C A T G G A T G G T T C C A T C C A A C C T A C C T T G G T A G C T T C G A A C G A A C G T A C C A T C C A A G C A T G G A A G G T A C C T T G G T T C G T T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T A C C T T G C A A C C A A G G T A C C T A C G T A G C A A G C T A G G A A G C T A G C T A C C T T G C A T C G A A C C T A G G T A C G T T G C T A G C A A C C T A G G A T C G T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C A A G C T A G G A T G G T T G G T A G C A T G C A T G G T A G C T T C G T A G C T T C G T A G C T A G C T T G C T T G G T T G C A A G G T T G C T A G G A A C C A T C G T A C C T A G C T T G G T A C C A A G C A T C C T T G C A A C C T A C G T A G G A A C C T A C G T A C C A T C C T T C G A A G C A A C C T A G C A A G C T T G G T A G G A A C C A T G C A A G G T T G C A T G G A A C G A T C C A A C C A T C G T A G G A A C G T T G C T T C C T A G C T T G C A A G C T T G C T T G C T T G G T A G C T A C C T A G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A C C A A G C T T C C T T C G T T G C T A C C T A C C T A C G A T C C A T C G A T C C T T G G T T G C A A G G A T C G A A G C A A C G A T G C T T G C T A C C A T G C T T G G A A G G T A C C T A G C T A C C A A G G T A G C T A C G T T G C A A G C T T G C T T C C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BOR_9518 # subpop. label: 4 (internally 4) -1 2 1 2 2 2 1 1 1 1 1 2 2 2 2 1 2 1 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 1 2 1 2 2 1 2 2 2 1 1 1 2 2 2 1 2 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 1 1 2 2 2 1 2 1 1 1 1 2 2 1 2 1 2 2 2 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C T T G C A T C G A A G C A T C C A T G G A A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C A A G G T A G G T T G G A T C G A A C C T T C G T T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T T G G A T C C A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G A A G G A T G C T A C C T T G G T T G C A T G G T T G C T A G G T A C G T T C G T A G C T A G C T A G G A A C C A T G C A T C G A A C G A T C C T A C G T A G C T A C C T A C G T A C C A T C C T T C G A A G G A T G G A A C C T A G C T T G C T T G C A A G C A T G C A T G C T T C C A T G G T A G G A A C G A A C G T T G G T T C G A T C G T T C C T T G C A T C G T T G C A T C C T A G C A T C C T T G G A T G C T A C G T A G C T A C G A A C C T T G G T A G G A T G C T A G C T A C C A A G C A A G C T T C C A T C G T T C C T A G C T A C C T A C G A T C G A T C G A A G C T A G G T T G C T A G G T T C G T T C G A A C G A A G C T T C C T A G C T T G C T T C G A A G C T T C C T A G C T A C C A T C C T T G C T A C C T T G C A A G C T T G C A T G C T A G C A A C G T A G G T T G C A A G C A A C C T A G G T A G C A A G C T A C G T BOR_9520 # subpop. label: 4 (internally 4) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 2 1 2 2 1 2 2 1 2 1 1 2 1 1 2 2 2 1 2 1 1 2 2 1 2 2 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 1 1 2 1 1 1 1 1 1 1 2 2 2 2 2 2 2 1 1 1 2 1 2 2 2 1 2 2 2 1 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 1 2 1 1 1 1 2 2 1 2 2 1 2 2 2 1 2 1 1 2 2 2 1 1 2 1 2 1 1 1 1 2 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 2 2 1 1 1 1 2 2 2 1 2 1 1 2 1 2 1 2 2 1 2 1 1 2 1 2 1 2 1 1 2 1 2 2 2 1 2 1 2 2 2 1 1 2 2 1 2 2 1 1 1 2 1 1 2 2 1 2 1 2 1 2 2 1 1 2 1 1 1 2 2 1 2 1 1 1 2 1 2 1 2 2 1 2 1 2 1 1 2 2 2 1 1 2 1 1 2 2 1 1 1 1 2 2 2 2 2 2 1 2 1 2 2 2 1 1 1 2 2 1 1 1 1 2 1 1 1 1 1 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A G C A T G C T A C G T A C C A A G C T T G C A A C G T T G C A A G C T T C G T T G C T T C C T A G C A T C G T A G C A A G G A T C C T T C C A T G G A A G G A T C C A T C G A T C G T A G C A T G C A A G C A A G G A T G C T A G C T A C G A A C G T T C G A A G C A A C G T A G G T T C G T A C G T T G G A T G G T A C C A T G C T T G G A A C G A A C C A A C C A A C G A T G C T A G G A T G C T T C C A T G C A A C C A T C C T A C C T A G G T T G G A T G C A A C C T A C G A T G C A A G C T A G G A A C G A A C G A T C C A A C G T A G G A A C C A A G G A T C C A T C G A T G C T T C G T T C G T T G C A T G G T T G C A T G G A A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G C A A C G T A G C A T C C T A C C T A G C A A C C A A G G T A C C T T G G T A G C A A G G A A G C A A G C T A C C A A G G T A G C A A G C T A C G A T G G T A C C T T G C T T C G T T G C A A G G T A G G T T G C A A G C T T C G T T G G A T C C A A G C T T G G A A G C A T C C T A G C A A C C A A G G T T C C T A G C A T C G T T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G G T A C G T A G G A A G G A A C C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G A A C C A T C C A A G C A A G C T A G C T T G G T T C G A T C C T T C C T T C G T A G C A T G G A T G C T A G C A A C C A T G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T A C G T T C C A A C C A A G C T A G C T A C G T A G C A A C C T A G G T A C C A A G G T A C C A A G C A T C G A T C G A A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C G T A G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T C G A A C C T T C G T A C C T A G G A A C G A T G C T A C G A A G G T A C C A T G G T T G C T A G G T A C G A T C C T A C C A A G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A G G A T G C T A C C A T C C A T C G A A C G A A G C T A G C T A G C T T C C T T C C A A C C A T G C A T G G T T G C T T G G T A C G A T G C T A G G A T G G T A G G A A C G T T C C T T G C A A C G T T G C T A C C T A G G T T G G T T G C A A G C T A C G T T G C T T C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A C C T A C C A T G G A A G C A A G G A T C C T A G C T T C G A T C G A T G C A T C G A T C G T A G G T T C G A T C G T A C G A A G C T T G C T A C G A T G C T T G G A A C C A A C C T T G C T A C C A A C C T T C C T A C G T T G C A A G C T T G G A T C C T A G C A A C G T A G C T A G G A A C C T T C C T A G C T A G C A A C G T A C C T +A C C T T G G A T G C A T G C T A C C T T G C T A G G T A G G T A C C A A G G T T C C T T G C T T G G A A C G A A G C T A G G T A G C A T G C A A C G T A C C T A G G T A G C A T G C A T G G T A G G T T G G T A G C A A G G T A G C T A G G T A G C A T G C A A C G A T G C A A G C T T C C A T G G T T G G T T G C A T C C T A G C A T G C A T G C T T G C A A C G A A G C T A C C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C T T C C T T G C T T G C T A G G T T C C T A G C T T C C A T G G T A G G A T G C T T G G A T C G T A G C T T C C A A C G A A G G T T G G A T G C T T C C A T G C A A G C A T C C T A C G A A C G T T G G T A C G A A C G T A C G T A C C A A C G T A G G A A C G T A C G A T G C T T C G T A G G A A G C A A G G T T C G A A G G T T C G A A C G T T C C T T G C A T G C T A G C T T C G T T C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C T T C C A A G G T A G G A T G G T A G C T T G C T A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G T T G C A T C C A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A T C G T A C C T T C G A T C C T A G C T A G G T A C G T T G G A A G C T A C C T T G C A T G C A T C C T A C G T T C G A A G C A A G C A A C G A T G G A T G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T A C G A T C G T A G C A A G C A T C G T A G C A T C C A T G G T A C G A T C C T A C C T T C C A A G G T A C C A A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T A G G T A G C A A G C A A G C T A C G T T C G A A G G T A C G T T G C T T C G A T C G A A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G G T A C C A A G C A T G G T T C G T A G C A T C G T T C G A A C C T T C G T A G C T A C G A A G G A T G C A T G G T T G G A A C C T A G G T T G C T A G G T A C G T T C G T A G C A T G C T A G G A A C C A T C G A T G G T A C C A A C C T T G C T A G C T T C G T A G C T A C C A T C C A T C G A T G G A A G C T A G C T A G C A T G C A A G C A A C C A A C G T T G G T T G C A T G C A A C G A T G C T A C C T T G G T A G G T A C G A T C C T T G C A A C G T T G C A A G C A T G C T T C G T T G C A T G C T A C C T A G C T A G G T T C G T A C C T A G C A T G G T A G C T A G G A A G C A A G C T T C C A T C G T T C C A A G C T A C G T T C G A T C G A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A C G A A G C T T G C T A C G T A G C T T G C A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G G T A C C T A G G T A C C T A G C T A G G A A C C T A G C A BOR_9524 # subpop. label: 4 (internally 4) -1 2 1 2 2 2 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 1 1 2 2 2 1 2 2 2 2 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 2 2 2 1 1 2 1 1 1 1 1 1 2 2 2 2 1 2 2 1 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 2 2 2 1 2 1 2 1 2 1 2 2 2 2 2 2 1 2 1 1 1 1 2 2 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 1 2 2 1 2 1 1 1 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 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G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G G A A G C T A C C T A G G T A C G T A G C A A G C T T G G A T C C A A C C A A C G T T G C A T G C A A G G T A G C T T G G A A G G T A G C A T G G T A G C A A G G A T G C T A G C A A C C T A G G T A C C A A G C T T C C A T G G T A C C T T G C T T C G T T G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G T A C C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T A G G A A G G T T G C A T C G T A G C A T G G A T C C T A G C T A G C T T G C T A G G A A G G T A G G T T G C A T G C A T C C T T C G T T C G T A G C A T G G T A C C A T G C A A G G A A G C A T C C A A G C A A C C T T C C T T G C T T C C A T C C T A C G A A C G T A G C T A G C T T G C T A G C A A C C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T T C G T A G G A T G G A A C G T A G G T A G C A T G C A T C C T T C C T A G C T A C G A A G G T T G C T T G G A T G G A A C C T A G G T T G C T A G G A A C G T T C G T A G C A T C C T T G C A A C C A T G C A T C G A A C G A T C C T T G C T A G C T A C C T A C G T A C C A T C C A T C G A A G G A A G G A A C C T A G C T T G C T T G C A A G C A T G C T T C C T T G G A T G G T A C G A A C C T A C C T T C G T A C G A A C G T T G C T T C C T A G C A T G C T A G C A A G G T T G G A T G C A T G C T A C G T T G C T A C G A A C C T A G G T A G G A T G C A A G C A T G C A A G G A A G C T T C C T T C G T T G C A A G C T A C C A A C C A T C G A T C G A T G C A A G G T T G C T A G G A T G G T T C G A A C G A T G C T T G C A A C C A T G C T T G G A A G C A T C C T A G C T A C C A T C C T T G C T A C G T T G C A A G C T T G C T T G C T A G C A A C G T A G C A T C G A A C C T T C C T A G G T A G C A A G C T A C G T +A C C T A G G T A C G T T C C T A C C T T C G A A G G T A C G T A C C A A G G T T C C T T G C T T G G A A C G T A G C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A T G C T T G G T T G G T T G G T A C C A T C G T A C C A A G G A A G C A T G G A A C G T T G C A A G C T T C C A T G G T A G G T T C G A T C C A A G C A T C C A T C C A T C G A A G G A A G G A A C C A T C G T T C G T A C G A T G C A A C G A A C G T T G C T A G C T A G C A A C G T A C C T A G C T A G C A A G C T T C G T A G G T T G G A A G G T A G G A T C C T T G G A T G G A A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C T A G G T A G G A A G G T T C G T A G G T A C C A A C G T A G G A A C G A A C G A T G C T A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G C A A C G T T G C A T G C A A C C T A G C A A G C A T C G T A C C T T G G T A G C T T G G T T G G T A G C T A C C T T G C T T G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T C C A T C C T A C G A A G C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C A A C G A A G C T T C G T T C C T A G C T A G C A A C G T A G C T T C C T A C C T T G C A A G C A T C G T T C C A T G C A A C G A A G C T A C C A T G C A A G G A T C G A T C C A A G C A A C C T T G C A T G G T T C G A A C G A A C C T A C C T T C G A T G C T T G C A A G C A A G C A A C G T T C G A A G G T T C C T A G C T A G G A A G C A A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G A A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C G A A C G T A G G A T G C A T C G A A C C T T C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T G C T T G G A A G C T T C G T T G C T A C G T A G C T T G C T A C C T T G G T T G C A T G G T A G G A A G G T A C G T T C G T A C C T A G C A T G G A A C C T T C G A T C G A A C G A T C C T T G C T A G C A A G G T T G C T A C G A T C C A T G G A A G G A A G C T A G C A A C C T T G C T T G C A A G C A T G C A T G G T T G G T T G G T A C G A A G G A T C G T T C G T A G G A T C G T T C C T T G C A T C G T T G C A T C C T A G C A T C C T T G C A A G C T A C G T A G C T A C G A A C C T T G G T A G C T T G C T A G C T A C C A A C C A A G C T T C C A T C G T T C C T A G C T A C C T A C G A T C G A T C G A A G C T T G G T T G C A A G G A A G G A T C C T A C G A A G C T T C C T A G C T T G C T T C G A A G C T T C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C C A A G C A A G G T A G C A A G C A A C G T BOR_9525 # subpop. label: 4 (internally 4) -1 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 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T C G T A G G A A C G T A C C T T C C A A G C A T C C T A C C T A G C T T G C T T G G T A G C T A C C T A G C T A C G A A C C T T G G T T G C T T C G A A G C T A C C A A G C T A G C T T C C A T C G T T G C T A C C T A C C T A C C T A C C A T C C A A G G T T G G A T G C A A G C A T G C T A G C T A G G T A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C T A G G T A G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A T G C T A G G T +A C G T A G G A T C C T A G C A A C C T T G C T A G G T A C G T A C C A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A C C A T G C A T G C A A C C T T G G T A C C A T C C A T G G A T C C T T C C T A C C A T C C T A G G T A G G T A G C A T G C A T C G T A G C T A C C T A C G A A G C T T G C T A G C A T C G T A G C A T C C A A C C T T C C A A C G T A G G A A C G T T C G T T C G T A C C T A G G A A G C A A G C T T G C T A C C T A G C A A C C T T C C A A G C A A C G T A G G T T G G T A C C A T G G T A G C T A C C T A G C T A C G A A C C A A G G T T C C T A C G T T G G T T G G A T G C T T G G T T G C T A C C A T G C A A C C A A G G A T C C T A G C T T C C A A G G T A G G A A C C T A G G T A C G T A C G A T G C T A G C A A C C T T C G T T C G A A G C A A G G T T G G T A C G A A G C T A G C A T G G T A G C T T C G T A C C A T C G T A G C A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A C G T A C C T T G G T A C C T A G G A A G C T A G C T A C C T T G C T T G C A A G C A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T T C C A A C C A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C T T G G A A G C T T G G A T C C T A G C T A G C A T G C T T C C A A G G T A C C T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A G C T T C C T T G C T T C C A T C G A A C G A A C C T T C C A A G C A T G G A A G G T A C C T T G C T A C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C A T C C T T G G A T C G A T G G T A C C T A G G T A G C A A C C T A G G A A G G A T C G A A C C A T G C A T C G A T C C T T C G A A C G T T G C T A G G A T C C T A G G A A C G T A C C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A A C C T A G G A T G C A A G G A T C C T T C G T A G C T A C G T A G G T T G C T A C C T T G G T T G C A A G G T A G C T A G G T A C G T A C G T A C C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T T G C T T G C T A G G T T G C T A C C A T G G A T G G A A G G A A G C T A C C A A G G A T G G T A G G A A C C A T G C A A G G T T G G T T G C A A C G A T G C A T G C T T G G T A G C A A C G T T G C T T C C A A G C A T G C T A G C T A G C T T G G A T C C A A G C T A C C T A G C T A G G T T C G T A G C T A G C T T G G T A G C T A G C A A G C T A G C T T C C A T C C T T G C A A G G T A C C A A C G A T C C A T C C A T G C T T G G A T G C T A G C A T G C T A G C T A C G T A G C T T G C T A C C T T G C T T G G A T G C A T C C T T C C A A C C A A G C T T G C T A C C T T G C A A G C T T G C T T C C A A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BOR_9526 # subpop. label: 4 (internally 4) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 1 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 2 1 2 2 1 2 1 1 2 2 2 1 1 1 2 2 2 2 1 2 2 2 1 2 2 2 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 2 1 2 2 1 2 1 1 2 2 2 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 1 1 2 2 1 1 1 1 2 2 2 2 2 2 1 1 2 2 2 2 1 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 1 2 2 2 2 2 1 2 2 1 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 2 2 2 1 1 1 2 2 2 1 2 1 1 2 1 2 1 2 2 2 2 1 1 2 2 2 1 1 1 1 2 2 2 2 2 1 1 1 2 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C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T G C T A G C T A G C A T C C A A G G T A G C T T G G A A C G T A G G A A G C A A G C A A G G A A G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T T C C A A G C T T C G T T G C A T C C A A G G A A G G T T C G A T G C T A G C A T C G T T C C T A C G A A G G T A G C T T C G A T G C T T G G A T C C T A G C T A G C A T G C T T G C A A G C T A C C T T G C A T G C A T C C T T G G A A G G T A G G A A G C T A G C A T G C A A G C T A C C A T C G A A G C A A G C T T G C T T G G T T C C A T C C A A C G T A C G T T G C A A G C A T G G A A G G T A C C T T G C T A C G A A G G T A C G T A C C A A G G T A C C T T G C T T G C T A G C T A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G C T A C C T A C G T A C C A A C C T A C G T T C G A T C G T A C C T T G C A T C G A A C C T A C G A T G G T T G C T A G C A A C C T A G G A T C G T T C C T A G C A T C C A T G G T A C G T A G G T T G C A A G C T T C G T A C G A T C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G T A C G A T G C T T G G T T G G T T G C A T G G T T G C T A G G T A C G T A C C T A C C T A C C T A C C T A C C A T G C A T G G T T G C A A C C T T G C T T G C A T G G T T G C T A C C A T C C T T G G A A G G A A G C T T C C T A G C T T G C T T G C A T C C T T G C A A G G T T G C A T G G T A G G A T C C T A C G T T C G T A G G A A C G T T C G T T C C T A G C A T C G A A G C A A G G T T G G A T G C T T G C T A C C T A G C T A G G T T C G T A C C T A G C A T G C A A G C T A G C A A G G A A G C T T G C T T C G T T G C T A C C A A C C T A G C A T C G A T C G A T G C A T G G T T C C T A G G A T G G T A G C T A C G A A G C T T G C A A C C A T G C T A G G A A G G T A C C T A G C T A C C A A G C T T G C T T C G T T G G A A G C T T G C A T C C T A G C A A C G T A G G T T G G A A G G A A C C T A G C T A G C A A C G T A C C T +A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G G T A C G A A G G T A G G A T G C T T G G A A C G A A G C T A G G T A G C T A C C T T G C T A G C T T G G T A G C A T C C A T G G T T C C T T G G T A G C A T C G T A C G T A G G A A C C A T G C A A C C T T G C A A G C A A C C A T G G T T G C T T G C A T C C T A G C A T C C A A C C T T C C T T C G A A G C T A G G A A G C T T C G T A G C T T G C A T C C A A G G A A C C T A G C T A C C A A C G T T C C A A G C A A C G T A G G T T G G T A G G T T G G T A C G T A G C A T G C T T G G A A C G T A G C T T C C A A C G A A G G A A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G A A C G A A G C T A C G T A C G T A C C A A C G T A G G A A C G T A C G T T C C A A C G T A G G T T C G A A G G T A G G A A C G T T G G T T G G A A G C T T G C T T G G T T G C T T C G T A C C A T G G A A G C A A G G A A G C T T C G A A C C T A G C T A G G A A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T G C T A G C A T C C T T G G A A C G T A C C T T G G T A C C T A G G A T G C T A G C A A C C T T G G A A G C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G G T T C C T T C G T T G G T A G G A A G C A T G C A A G C T T C C A A G C A A C C T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G C A A C C T T G C T T C C T A C C A T G C A A G C A T C C T T C C A T G G T A G C A A G C T A C C A T G G A A G C T A C C A T C G A A G C A A C C T T C C T T G C T T C C A T C G A A C G A A C C T T C C A T G C A T G G A A G G T A C C T T G C T A C G A T G G T A C C T A C C A A G G T A G C A A G C T A C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T A C C T A C C A A G C A A G C T A C G A A C G A A G C T A C C T T G G A T C G A A C C T T C G T T G C T T G C T A G G T A G C A A G G A A C G T A C C T A G C A T C C A T G G T A C G T A G G T A C C A A G C T A C C T T G G A T C C A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G A A G G A T G C T A C C T T G G T T G C T T C C T A C C T T G G T A C G T T C G T A G C T A G C A A G G A A C C T T G C A T C C T A C G A A C C T T G C T T G C T A G G A A G G T T C C A T C C T T C G A A G C A A G C T A G C T A C C T T G G T A G G A A C C A A C G T T C C T T G G A T G G T A G G A A C G A A G G T T C G T A G G A A C G A T C C T T G C A A C G T A G G A A C C T A G C A T C C T T G G T A G C T T C C T A G C T A G G A A C C T A G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T T C C T A G C T A C C T A C G A T G G A T C G A A G C T A G C A T G C A A G G A T G G A T C G A A C G A A G C T T G C T A G C T T G C T T G G A A G G A T C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G C T A C C T A G G T T G C T A G G T T C C T A G C T A G C A A G C T A C G T BOR_9527 # subpop. label: 4 (internally 4) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 2 2 1 2 2 1 2 1 1 2 2 1 1 2 2 2 1 2 2 1 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T C C A A G G T A C C A A G C T T G C T T C C A A G C T A G C A A G G A A G C T T C C T T G C A A C G A A G C A T C C T A C G T A G C A A C C T A C G A A G C T A G G T A C C T T G C T T C G A A C C T T C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T T G C A A G C T T C G T A C G A T C G A T C G T A G C A A G C A T G G A A G C T T C C T A C C T T C G T A G G T T G C T A G G A A G G T T G C T T C C T A C C T T G G T A C G T T C G T A C C T A G C T A C C T A C C T T G C A T C C T A C C A A C C T T G C T T G C A A G G T A G G T T C C A T C C T T G C T A G G A A G G A A C C T A G C T T G C T A G C A A C C T T G C A T G C T T G G A T G G A A G G A A G G A A G G T T G G T T G C A T C C T T C C T T C C T A C G T T G C T A G C T A G C A T G G T T G C A A G C T A C G T A G C T T C G A A C C T T G G T A G C T T C G A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A G C T A C C A A G C T T C G A T C G A T G C T T G G A T G C T A C C A 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C T A C C T T G C T A G G A A C G T A C C A A G G A T G C T T G C T A G G T T C G A T C C T T G G T A G C T A C C T T G C T T G C A T G C T A G C A T G C A T G G T T C G T T G C T A G C A T C C T A G C A A C G A A G G A T G G A A C G T T C C T A G C T T C C T T G G T A G G T T G C A T C C T A G C A T G C A T G C T T C C T T G G T T G C A A C C T A G C T T G G T A G C A A G C A A C G A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T C C T T C C A A C G T A G C T T C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G A T G C A A C C T A C G A T G C A A G G T A G G A A C G T A C G A T G C T A G C T A C C T T C C A A G G T T C C A T C G A T G G T T C G T T C G A T C G T A C G T T G C T A C G T A C G A T C G A A G C A A C C A T G C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A G C T T G G A A G C T A G C T A C C T T G G T A G C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A T C C T A C G A A G C A A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T A C C T T C G A T C C T A G C T A G G T T C C A T G C A A G G T A C C A T G G T A G C A T C C T A C G A T G C A A G C A T G G T A C C A T G G A A G C T A G C A T C C A A G C A A G G T A G C T A G G T T C G A T G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T C G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G C A A C G A A G C T T C C T A C G T A C C A A C C T A C G A A G G A T C G T A C G T T G C T T C G A A C C T T C G A A C G A T C G T A C G A A C C A A G G A T G C T A C C A A G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A G G A T G G A A C G T A G C A T G C T T G G A T C C T T C G T A C C T A G C T A G G T T G C T T G C T T G G A T G C A T C C T A C C T A G G T A C G T T C G A A G C T A C C A T G G T A C C A A G C A T G G T T G C A A C C T A C G T T G C A T G G T T C G T A C C A T C C T T C C T A G C A A G C T T G C T A G C T T C C T T G C A A C C A A G C A T G C T T G G T T G G T A G G A T G C T A C C T T G G A A G G A T G G T T C C T T G C A A C G T A G C A A G C T A G G T T C G T T G G A A G C T T C C T A G C T A G G T T C G T T G C T A G C T T G C A A G C T A G G A A G C T A G C T T C C A T C G T A C C T A C C T A C C T A C G A T C C A T C G A T G C A T G C A T G C T A G G A A G G A T C C A A C G A A G C T T C C A A C G A T G C T A G G A A G G T A C C A T G C T A C C A A C C T T G C T A C G T T G G A A G C T T G G T T G G T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C A A G G T A C G T T G C T A C C T T G C T A G G T A G G T A C C A A G G T T G C T T C C T T G G T T C G A T G C T A G G T A G C T T C C A T C G T A C C T T G G T A G C A A C G A T G G A T C G T T G C T A C C A T G C T A C C A A C G A A G G A T G C T T C G T T G C T A G C T T C C T T G G T T G C T T C C A T C C T A G C A T C C A A C C T T G C A T C G A T G C T A C C A T C G T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A C C A T G C A A G G T A G G A A G C T T C G T A C G T T G G A A G G T A G G T T G C T A C C A T G G T A G G T T C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C T T G C T A C C A A G G A A G G A A G G A A C G T A C G A T G C A A G G T A G G A A C G A A C G A T G C T A G C A A C C T T C G T A C G T A G C A A G G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G G T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C A T C C T T C C T A G C A A C C A A G G T A C C T T G G A A G C T T G G A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T A G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C T T G G A A G C T T C C A A C G A A G C A A G C T T C C T A G C A A G G T T C G A A C G A A G G T T G C T T C G A T G C T T G G A T C C T T G C T A G C A T G C T A G G A A G G A A G C T T G G T T G C A T C C T T C G A T G G T A G G A T G C T A G C A T G G A A G C T A G C A T C C A A C C A A G C T T C C T T G C T T C C A T G C A T C G T T C C T T G C A A G C A T G G A A G G T A G C T T G C T A C G A T C C T A C C T T C C A T G G T A C C T A C C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G A A C G A T G G T A C C T A G G T A C C A A G C T A C G A A G C T A G G T A C C A T G C A T C G A A C C T T C G A T G G T T G C A A C G A T C C T A G G A T C G T T C C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G G A T C G A T C G T A G G A T C C T T G G A T C C T T C C T A G C T A G C T T G G A T G C T A C C T T G G T T G C T A C C T A C C T A G G T A C C T A C C A T G C A T C C T T G G T A C C A A G C A T C C T A C C A T C C T T G C T T G C A A G G T T G C T A C C A T C C T T C G A A G C A A G C T A G C T A G C T T G C T T G C A A C C A T G C A T G G T T G C A T G G T T G C A A G G A T G C T T G G T T C G A T G G A T C C T T C C T A G G T A G C T A C C T A G G A T G G A T G C A A G C T A C G T T G G T T C G A A C C T T G G T T G C T T G C A A G C T T G C A A G G A A G C T T C C A T C G T T C C T A G C T A C C A A C G A T C G A T C G A A G C A T C G A T C G T A G G A T G C T A G C T A G G T A G G A A G C A A G C A T C C T A G C A A G G T A C C T A G C T A C C T A C G T A G C T A G G T T G C A A G C T T G G T T G C T T G C A A C C T A G C A A G G T A C C T A C C T A G C T A G C A A C G T A C C T BOR_9529 # subpop. label: 4 (internally 4) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 2 2 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 1 2 1 1 1 1 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 1 1 1 2 1 1 2 1 1 2 1 1 2 2 2 2 2 2 1 1 1 2 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T G C T T C C T T G C A T C C A T G C A A C C A A G G A T C C T A G C T A C G A A G G T A G C A A C G T A G G A A C G A A C G A T G C T A G C A A C C T T C G T A C G T A G C A A G G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T C G A A G C A A C C A T G C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A A C G T A C C T T G G T A C G T A G G A A G G A A C G A A G G A A G G T A C C A T C G T A C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T T C C T T C C T T G C T A C C A A G C A T C G A A G C T T C C A A C G A A C C T A G C T A G C T A G C A T C G T T C C T A C G A A G G T T G C T T G G A T C C A T G G A T C C T T G C T A G G T T G C T T G C A A G G T A C C T T G C A T G C A T C C T T C G A T G G T A G G A T G C T A C C A T G G A T G G T T G C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C T A G C T T G C T A G C A A C C A A G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A G C T T C C A A C C T A G C A T C G A A G C T T C C A T G G A A C G A T G G T T C C T A C G T A C C A A C C T A C G T T C G A T C G T A C G T T G C T T C G A A C C T T C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C A A G C A T C C A T G G A A C G T T G G T T G C A A G C T A C G T A G G A T C G A T C G T A G G A A G C A T G G A A G C T T C C T A C C T T G G A A G G T T G C T T G G T T G G A T G C A T C C T A C C T A G G T A C G T T C G A A G C T A C C A T G C T A C C T T G C A T C C T A C C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C C T A G C A A G C T A G C T A G C T T C C T T G C A A C C A A C G T T C C T T G C A T G G A A G G A T G C T A C C T T G G T T C G A A C G T T C C T T G C A A C G T T G C A A G C T A G G T T C G T T G C A A G C T T C G T T G G T T C G A A C C T T G G T A C C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T A C C T A C C T A C C A A C G A T C G A T C G A A G C A T C G A T C G T A G G A T G C T A G C T A G G T A G G A A G C A A G C A T C C T A G G A A G G A T C C T A G C T A C C T T C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G C T A G C A A C C T A G C T A G C A A G C T A C G T +A C C T A G G A T G G T T C C T A C C T T G C T A G G T A C G T A C C A A G G T T G C T T G C T A G G T T C G A T C C T T G G T A G C A T G C A T C C T A G C T T G G T A G C A A C C A T G G T A G G T T G G T A C C A T C C T A G C A A G G A A C C A T C G A A C G T T G C A A G C A T C C T T G G T A G C T T C C A T C C T A G C A T C C A A C C T T C C T T G G T T G C A A C C T A G C T T G G T A G C A T G C A A G G A A G G A T G C A A G C T A G C A A C G T T C C T A G C T A C G T A G G T T C G T A C G T T G G A A G G T A G G T T G C T A C C A T C G T A G G T T C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C T T G C T A C C A A G G A A G G A A G G A A C C T A C G A T G C A A G C T A G G A T C G A A C G A T G C A A C G T T G C A 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A G C A A G C T A C G A A G G A T C G T A C C A T G C A T C G A T C C T T C G T A C G A T C G T A C G A A C C A A G G A T G C T A C C A A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G G A T G G A T C G T A G G A T C C T T G G A T C C T T C C T A C C T A G C T T G G A A G C T A C C T T G G T T G C A A G G T A G C T A G G T A C G T T G G A A G C T A C C A T G G T A C C A A G C A T G G T T G G A A C C T A C G T T G C A A G G A T G G T T C C A T C G A T C G A T G G A A G C T T C C A A G G T T G G T A G G A A C C A T G C A T G C T T G G T T G G T A G G A T G G A A G G A T G G T T C G A T G G T T C C T T G C A A C G T A C C A A G C A T G C T T G G A T C C A A G C A A C G T A G C T T C G A A C C T T G G T T G C T T G C A A G C T T G C A A G G A A C C T T C C T T C G T A G C T A C G A T C C A A G C A T C G A T C G A T C C A T C G A T C G T A G G A T G G A T C C A A C G A T G C T T G C A A C C T T G C T T G C A A G G T A C C T A G C T A C C T A C G T A G C T A C G T T G C A A G C T T G G T T G C T T G C A A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T BOR_9530 # subpop. label: 4 (internally 4) -2 2 1 2 1 2 1 1 1 2 1 2 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 2 1 2 1 1 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 1 1 1 1 1 1 2 2 1 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 1 2 1 2 1 1 1 1 2 2 1 1 2 2 2 1 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 1 1 1 1 2 2 2 2 1 1 1 2 2 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 1 2 2 2 2 2 1 2 1 1 2 2 2 1 2 1 1 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 2 2 2 2 2 2 1 2 1 1 2 1 2 1 2 2 1 2 1 1 2 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 1 2 2 2 1 1 2 1 1 2 2 1 2 1 2 1 2 2 1 1 1 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 1 2 1 1 2 2 1 1 1 1 2 2 2 2 2 2 1 2 1 2 1 1 1 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 1 2 1 1 1 2 1 1 2 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 1 1 2 2 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C T T C C T T C G T T G C T A C C A A G C A T C G A A G C T T C C T A C G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T T G C T T G G T A G C T T G G A T C C T A G C T A G G T T G C T T G C A A G C T A C C A T G G T A C C A T C G T T C G T T C G A A C G A A G C T A C C A T G G A A G C T T G C A T C C A A C C A A G C T T C C T T G C T T C C A T G C A T C G T T C G T T G G A A G C A T G G T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T A C C A A G C A T C C T A C C T T G C A T C G A A G C A T C C T T G G A A C G A T G G T A C C T A C G A A C C A T G C T A C G A A G G A T C G T A C G A T G C T T C G A A C C T T C G T A C G A T C G T A C G A A C C A A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G G A T G G A T C G T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A G G A T G C T T G G T T G G A T G C A T C C T A C C T A G G T A C G T A C C T A G C T A C C A T G C T T C C A A G C A T C C T A C C A A C C T A C G T T G C A A G G A T G G T T C C A T C C T T C C T A G C A A G C T T G C T A G C T T C C T T G C A A C C A A C G T T C C T T G G T T G G T A G G A A G C A A G C T T G G T T C G A T G G T T C C T T G C A A C G T T C C A A G C A T G C T T C G T T C C A A G C A A C G T A G C T T C G A A C C T T G G T A C G T T G C A A G C T A C C A A G G A A C C T T C C A T C G A A G C T A C G A T C C A A G C A T C G A T C C A T C C T T G C T T C G T A G C A T G C T A G C T A G G T A G G A T G C T A G C A T G C T T G C A A G G A T C C T A G C T A C C A A C C T T G C T A C C T T G G A A G C T T G C T T C C T A G C T A C G T A G C T A G C A A C G A A C C T A G C T A C C A A C G T A G C T +A G C T A G G T A C G T T G C T A G C A T C C T A G C T A G C T A C G A A G G T T G G T T G C T T G C T T G G A A G C T A G G T A G C A T G C A T G C T A G C T T G G T A G C A A C C T T G G T T G C A T G G T A C C A T C C T A G C T A G G A T G G A T G C T T C G A T G C T A G C T T C G T A C C T T G G T A C C A T C C T A G C T T C C A T G G T T C C A T G G T A G G A A C C T A G C T T G G T A G C T T G C A A G G A A G G A T G C T A C C T A G C T A G C T T G C T A G G T A G C T A G G T T G G T A G C T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A A C G A T G C T A G G A A G G T T G G T T G C A A G C A T C C T A C G A A C G T A G G A T G G A A C G A A G G T A G C A A C C T A G G A T C G A A C G A T G C A A C G T T G C A A C G T A C G T A G G A A G G T T G G T T G G T T C C T A G C A T G G T A G C A T G G A A C C A T G G A A G C A A G C A T G C T A C G A A G C T A G C T A G G T T G G A T G C A A C C A T G G T A C C A A C C A A C G T T G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A C C T A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C C T T G G T A C C A A G C A T G G A T G C T A C C A A C G A A G C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T T G C A A C G T T G C A T G G A T C C T A C C T A G G T A C C T A G C A A G G T A C C T T G C A T G C A T C C T T C G A T G G T A G G A T G C T A C G A T G G A A G C T A G C A T C C A A G C A A C C T T C C T T G C T T C G A A G C A T C G T T C C A A C C A A G C A T G G A A G G T A G C T T G C T A C G A T C C T A C C T A C C A T G G T A C C A T C C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G A A C G A A G G T T C C T A C G T A C C A A C C T A C G A A G G A A G C T A C G A T G C A T C G A T C C T A C G A A C G T T G C T A G C A A C C T A G G A T C C T A C C A A G C A T C C A T G G T A C G T A G G T A C C A A G C T T C C T A G G A T G G A T C G T A G G A T C C T T G G A T C C T T C C T A C C T A G C T T G G A T G C T A C C T T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G G T A C C A A G C A T G G T T G C A A C C T T G C T A G C A T G G T T G C T A C G A T C C A T C G A A G C A A G C T T C C A A G C T T C C T T G C A A C C A T G C A T G C T T G G A T G G A A G G A T G C T A C C T T G G T A C G A T C G T T C C T T G C A T C G T T G C A T C C T A G C A T C C T T G C A T G C T A C G T A G C T A C G A A C C T T G G T A G C T T C G T A G C A T G C A A G G A A C C T T C C T T C G T A G C A A C C T A C C T A C C A T C G A T C G A T G C A T C G A T C G T A G G A T G G A T C C A A C G A T G C A T G C T A C G A T G C A T G G A A G C T T C C T T G C T A C C T T C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C T A G C A T C C T A G C T A G C A A G C T A C G T BOR_9531 # subpop. label: 4 (internally 4) -2 2 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 2 2 2 2 2 1 1 2 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 1 2 1 1 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 2 2 2 1 2 1 2 2 1 1 2 1 2 2 2 2 1 2 1 1 1 1 2 2 1 1 2 2 2 1 2 2 1 2 1 1 2 2 2 1 1 1 1 1 2 2 2 2 2 2 2 1 1 1 2 2 2 1 2 1 2 2 2 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 1 2 1 1 2 2 1 2 1 1 1 2 1 1 2 1 2 1 1 2 1 2 1 1 1 2 2 2 1 1 1 2 2 2 2 2 2 1 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T G C A A C G T A G C A A C G T A C G T A G G A A G G T T C G T A G G A A G C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C A A G G T A G C A T C G A A G G T A G G A T G G T A C G T A G G T T G C A A C G A T C G A A G G T A G G A A G C T A C C A T C C A A G C T T G C T A C C T T G C A A G G T A C C T T G G A A G C A T C G T A C G T A C G A A G C T T C G A A C C A A C G A T C G A A C C T A G C T A C C T A C C A A G G T T C C T A C C T A G G A T G C T T G G A A G C T T C G A T C C T A G C T A G C T A C C T T G C A A G G T A C C A T G C T A G C A T C C T T G G T T G G T A G G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C A A G C T T C G A T G C T A C G T A C C T T C C A A G C A T G G A A G G T A G C T T G C T A C G A A C C T A C C T T C C A A G G T A C C T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G A T C G A A G C T T C C T A C G T A C C A T G C T T C G A A G C T A G G T A G C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T C G A A C C T A G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T T C G T T G C A A G G A A C C T T C C A A C C T T C G T A G G A T G C T A C G T T G G T T G C A T G G T T G C T A G G T A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C G A A C C T T G C T T G C A A G G T T G C T T G C A T C C T T C G A A G C A A G C T A G C A A C C T T G G T A G G A A C C A T G C A A G C T A G G A T G G T A G C A T G C A T G G A T G G T A G G A T G G T T C C T T C C T A G G T A G C T A G C A T G C T T C C T T G G T T G C T T C C T A G C T A G G T T C G T T C G T A G C T T G G T A G C T A C G A A G G A A G G T T C C A T C G A A C C A A G C A A C C A A G C A T C G A T C G A A G C A T G G T T G C T A G G A T G G A T C C T A C G A A G C T T C C A A C C T T G C T T C C A A G C A T C C T A C C T A C C A A C C T T C C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G C A A G C A A C C T A G C T A G G T A G C A A C G T +T G C T A G G A T G C T A G C T A C C T T G G T A G G T A C G T A C G A A G G A T C C T T G C A T G G T T G G A A G C T T G G T A G C A A G C A A G C T T G C A T G G T A G C A T C C T T G G T T G G T T G G T A G C A T C G T A C G A A G G T A C G A T C C T A C G T T G C A A G C T T C G T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C G A T G G A A G G A A C C A T C G A A C C T A G G T A G C A T C G A A G G T A G C T A G C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T A C C T T C C T A G G T A C C T A G C T T G G A A G G A A G C A A C C T A C G T T G G A A G G A T G G T T G G T T G C A A C C A T G C A A C C A A G G T A G G A T G G T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G G T T C G T T C C A T C G T A C G T T G C T A C G A A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G T A G G A T G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G A T G G A A G C T T G G A A G C T T C C A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T G G T T G C T T C G A T C C T A G C T A G G T T G C T A G C A A G G A A G G T T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G C T A G C A T C G A A G C T A C C T T C C T T G C T T C C A T C G A A C C T A C G T A G G A A G C A T C G A A G C A A G C A A C G T A C G A A C G T A C G T A C C A A G G T A C C A A G C T T G C T T C C A A G C T A G C A A G G A A G C T T C C A T G G T A C G A T G G T T C C T A C G T A G C A A G C T T C G A A G G A T C G T A C C A T G C T T C G A A C C T A C G A T G G T T G C A T C G A A C C A A G G A A C G T A C C T A G C A T C C A T G G T A C G T A G G T T G C A A C C T A C C T A C G A T G C A T C G T A G G A T C G T T C G A A C C T T C C T A G C T T C G T A G G T T G C T T G G A A C G T T G C A T G G T A G C T T G G T A C G T T G G A A C C T A G C T T G C T T C C A A G C A T C C T T G C A A C C T T G C T A G C A A G G T T G C T A C C A T C C T T C G A T G G A A G C T A G C T A G C T T G C A A G C A A G C A T G C A A G G T T G G A T G G A A G G A A G G A A G G T T C G T A G G A T G G T T C C T T G C A A C G T T G C A A G C A A G G T T G G T T G C A A G C A A C C T A G C T T C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G G A T G C A T C G T T G C A A C C A A C C A A G C A T G G A T C G A T G C T T G G T T G C A A G G A T G G A A C C A A C G A T G C T T G C T A C C A T G C T T G C A A G G T A C C T A G C T A C C T A G G T A G C T T G G T T G C A A G C T T G G T T G C T T G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BOR_9532 # subpop. 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A C G T T G G T T C G T T C C T T G G T T G C T T G C A A G C T A C C A A G C A A G C T T C C A T C C T T G C A A G G A A C C A A C G A T C C A T C C A T G C T T G G T T G C A A G G A A G G A T C G T A C G A A G C T T G C T A G C A T G C T T G C A A G C T T C C T T G C T A C C A T C C T T G C T A C G T T G C A A G C T T G G T T C C T A G C A A C G T A G C T T C G A A G G T A C C T A G C T A G C A A G C T A C G T BOR_9533 # subpop. label: 4 (internally 4) -2 2 1 2 2 2 1 1 1 2 1 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 1 2 1 1 1 2 1 1 1 1 1 2 2 1 2 2 1 1 2 1 1 2 2 1 1 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 2 1 2 1 1 2 1 2 2 2 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 1 1 2 2 2 1 2 2 2 2 1 1 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 2 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 1 1 2 2 1 1 1 1 2 2 1 1 1 1 2 1 2 2 1 2 1 1 2 2 2 2 1 2 2 1 2 1 2 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 1 2 2 1 1 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 1 2 1 1 2 2 2 2 1 1 2 2 2 1 1 1 2 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C T T C C T A G C T A C G T A G G A T G C T A C G A A G G T T G C A T G G T T G C T A G G T A C G T T G G A A G C T A C C A T G G T A C C A T G C T T C G T A C C A A C C T T G C T T G C A T G G A T G G T T C C A T C C A T G G A T G G A A G G A A C C T A G C T T G G T A G G A A C C A T C G T T C G T T G C A T G G A T G C A A G G A A G C T T G G T A G G A A C C T T C C T T G C A A C G T T G C A A G C T A G G T T G G T A G C A A C G T T C C T T G C T T C G T T C C T A G G T T G C T T C G A A G C T A C C A A G C A A G C T A C C A T C G A T G C A A G C T A C C T A C G A T C G A T C G A T G C T A G C T T C C T A G G A T G G T T C C T A C G A T G C T T G C T A C G A T G C A T G G A A G C A T C C T A G C A A C C A T C C T T G C T T C C T T G C A A G C T T G G T T G C T A G G A A C G T A G C T A C G A A C G A A C C T A G G T A G G A A G C T A G C T BOR_9534 # subpop. label: 4 (internally 4) -1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 1 2 2 1 2 1 1 1 1 2 2 1 1 2 1 2 1 2 1 1 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 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A C G A T C G A T G C A A C C T A G C A A G G T T C C T A G C T T G C T A G G T T G G T A C C A T G G T T G G T A C G T A G C T A C G A A C G A A G G T T C C A A C G A A G G T A G G T T G C T T C C T T G C A T C C A T G C A A C C T A G G A T C C T A G C T A C G T A C C T A G G A A G C T A G G A A C C A A C C A T G C T A C C T A C C T T C C A A G G A T G C A A G G T T G G T T G G A A G C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A T C G A T C G A A C C T A G C T A G G T A C G A A G C A T G G A T C G T A C C A T G C T A C G T T G C A T G C T A G G T A G C T T C C A A G G T A G G A T G C A A C C T T G G T A C G T A G C A T C G A A G G T A C C A T C G T A C C A T G G T T C G T T G C T T C G T T G C A A G G A A G G T T G C A A G C T T C C T T G G T A C C A A G C A T C G A T G C A T C C T A G G A A G G T T C G A T G C T A G C A T C G T T C C T A C G A A G G T T G C T T G G A T G C T T G G A T C C T T C C T A G C A T G C T T G C A A G C T A C C T T G C T T C C A T C C T T C C T T G C A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C T A C C A A G C A T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G C T T C G A A C C T A G G A T G G A A G C T A G C A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T T G G A T G C A A G G T A C C T A C G A T G G A T C C T A G G A T G C T T G G A A C C T T C G T T G C T T C G A A C G A T G C T T G G T T G G A A C C T A G G T T G C T A G G T A C G T T C C T A C C T A G C T T G C T A C C A T G C A T C G T A C C A A G C T T G C T A G G A T G G T T C C T A G G A T C C T T C C T A G C A A C G A A C C T A G C T T G G T A G C A A C C A T C C A A G G T T G G T T G G T A G C A T C G A A G G T T C C A T C G T A C C T T C C T T G C A A C G T A C G A T C C T A C G T T C G T T G G A T G C T T C G A A G G T A C G T T G G A A G C A A G C A T C G T A G C T A C C A A G G A A G G A A C C A T C G T T G C T A C G T T C C T A C G A T C G A T C G A A G C A T G G T T G C T A C C A T G C T A G C T A C G T A G G A T G C T A G C A T G C T T G G A A G C T A C C T A G C T A C C A A C G T A G C T A G G T T G C A A G C T T G G T T G C T T G C T A C C T A G G T T G C T A G G T A C C T A G C T A G C A A C G T A C C T +T G C T A G G T T C C T A G C A A G G T T C G A A G G A A C C A A C G A A G G A T C C T T G C T T G G A A G G A T C C T A G G T A C C A T G C A T G C T A G C T T G G T T C C T T C C A T C G T T C C T T G G T A G C A T G C T A C C A A C G A A G C A T C C T A C G T T G C A A C C T A C G T A G G T A G G T T G C A T C C T A G C A T C C A A C C T T C C T T G G A A G C T A C C A T C G T T C G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A A G G T T C C T A G C T T G C T A G G T T G G T A C C A T G G T T G G T A C G T A G C T A C G A A C G A A G G T T C C A A C G A A G G T A G G T T G C T T C C T T G C A T C C A T G C A A C C T A G G A T C C T A G C T A C G T A C C T A G G A A G C T A G G A A C C A A C C A T G C T A C C T A C C T T C C A A G G A T G C A A G G T T G G T T G G A A G C T T G C A T G G T T G C A T G G A A C C A A G G A A G C A A G G A T C G A T C G A A C C T A G C T A G G T A C G A A G C A T G G A T C G T A C C A T G C T A C G T T G C A T G C T A G G T A G C T T C C A A G G T A G G A T G C A A C C T T G G T A C G T A G C T T C G A A G G T A C C A T C G T A C C A T G G T T C G T T G C T T C G T T G C A A G G A A G G T T G C A A G C T T C C T T G G T A C C A A G C A T C G A T G C A T C C T A G G A A G G T T C G A T G C T A G C A T C G T T C C T A C G A A G G T T G C T T G G A T G C T T G G A T C C T T C C T A G C A T G C T T G C A A G C T A C C T T G C T T C C A T C C T T C C T T G C A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C T A C C A A G C A T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G C T T C G A A C C T A G G A T G G A A G C T A G C A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T T G G A T G C A A G G T A C C T A C G A T G G A T C C T A G G A T G C T T G G A A C C T T C G T A G C T A G G A A C G A A G G T A C G T A G G A A C C T A G G T T G C T A G G T A C G T A C C T A C C T A G C T A G C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A A G G T T G C T A C C A T C C T T C G A A G C A A G C T A G C A A G C T T C C T T G C A A C C A T C G T T C C T T G G T T G G A A G G A T G C A A C C T T G G T A G G A A C G T T C C T T G C A T C G T T G C T A G C A A G G T T G G T T C C A A G C T A C G T A G G T T C G A A C C T T G G T T G C T T C G T A G C A T G G A A G G A A G C T A C C T T C G T T G C A A G C T A C C T A C G T T G C A T C C A A G G A A G G T A C C A A C G A A G G A T C C T A C G T A G G A T C C T A G C T T G C T T G G A A C C T A C C T A G C T A C G T A G G T A G C T A G G T T C C T A G G T T G G T T G C T T G C T A C G T A G C A A G G T A C C T A G C T A G C T A G C A A C G T A C C T BOR_9535 # subpop. label: 4 (internally 4) -1 2 1 2 2 2 1 2 1 1 2 2 2 2 2 1 2 2 1 2 1 1 1 1 2 2 1 1 2 1 2 1 2 1 1 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 1 2 2 2 2 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 1 1 2 1 1 1 2 2 2 1 1 1 2 2 2 1 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 2 1 2 2 1 1 1 2 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 1 1 2 2 1 1 1 1 2 2 1 1 2 1 2 1 2 2 1 2 1 1 1 2 2 2 1 1 2 2 1 1 2 1 2 1 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 1 2 1 1 2 1 1 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 1 2 1 2 1 2 1 2 2 1 1 2 2 2 2 2 2 1 1 1 2 1 2 1 2 2 2 2 1 1 2 1 2 1 2 1 1 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 1 2 2 1 1 1 2 1 1 2 2 2 2 1 1 1 2 1 1 2 1 2 1 2 2 1 1 2 2 1 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1 1 1 2 1 1 2 2 2 2 1 1 1 1 2 1 2 1 2 2 1 1 2 1 1 2 2 1 2 2 1 1 2 2 1 1 2 1 1 2 1 1 2 1 1 2 1 2 1 2 1 2 2 1 2 2 2 2 1 1 1 2 2 2 1 1 1 2 1 1 2 1 1 2 2 2 2 1 1 2 2 2 1 2 2 1 1 1 2 2 2 1 1 2 2 2 2 2 2 2 1 1 2 2 1 1 1 2 2 2 2 1 2 1 2 1 1 2 1 2 2 2 1 1 2 2 2 1 2 2 2 2 1 2 2 1 1 2 1 1 1 1 1 2 2 1 1 2 2 2 2 2 2 2 1 1 2 2 1 2 2 1 1 2 1 2 2 1 2 1 2 1 2 2 2 2 1 1 2 2 2 2 2 1 2 2 2 1 1 2 2 1 2 2 1 1 1 1 1 1 1 1 2 2 1 1 2 2 2 2 2 2 2 1 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 1 1 2 2 1 1 2 2 2 1 2 1 1 1 2 1 2 2 2 1 1 1 2 2 1 1 2 1 1 1 2 1 2 2 2 1 1 1 2 1 2 1 1 2 2 1 2 2 1 2 1 1 2 1 2 1 1 2 2 2 2 2 2 1 2 1 2 1 2 1 2 1 1 2 2 2 2 1 1 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 1 2 2 1 2 2 1 1 1 2 2 2 2 2 2 2 1 1 2 1 1 1 2 1 2 2 2 1 2 1 1 1 2 1 2 2 2 1 2 1 1 2 2 1 2 1 2 2 2 1 1 1 1 1 1 1 1 1 2 2 2 1 1 1 1 1 1 1 1 1 2 2 1 1 1 1 1 1 2 1 2 1 2 1 1 1 1 2 1 2 1 2 2 2 2 1 1 1 1 2 2 1 1 2 1 1 2 1 1 1 2 1 2 2 2 2 2 2 2 1 2 1 2 2 1 2 2 1 2 2 2 1 1 2 1 2 1 1 2 2 2 2 1 2 2 2 1 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 2 2 1 1 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 +T G G T A G G T T C C T A G C A A G G T T C G A A G G A A C C A A C G A A G G A T C C T T G C T T G G A A G G A T C C T A G G T A G C T A C C T T G C T T G C T T G G T A G C T T G C A T C G T T C G T T G C T A C C A T G C T A C G A A C G A A G C A T C C T A C G T T G C A A C C T A C C T A G C T T G C A T C C A T C C T A G C A T C C A A C C T T C C T T C G A A G G A A C C A A G G T T C G T A G G A A G G A A C C A A C G T T G C T A C C T A G C A A C G T T C C T A G C T T G C T A G G T T G G T A C C A T G G T T G G T A C G T A G C T A C G A A C C A A G C T T C C A A C C A T G G T T G G A T G C T T C C T T G C A T C C A T G C T A C G A A C G T T G G T A C G T A C G A A C G T A G G A A C G T A G G A T C G T A C G A T G C T A G C A T G C T A G C A A G G T T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C T A G G A A G C T T C C A T G G T T C C T A G G A A G C T T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C A T C G T T G G T A C C A A G C T A G C A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G G A A C C T A G G A A C C A T C G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G T A C C A T G C T A C C A T C C T A C G T T C G A A C G A A G C T A C G A T G C A A G C T T G C A T C C A A G G A A C C T A C C T T G C T T C C A T C G T A C G A T C G T T G G A A G C T T G C A A G G T A G C T T G C T A C G A A C G T A C G T A C C A A G G T A C C A A G C T T G C T T C C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A C C T A C G T A G C A A G C T A C G A A C G T A G C T A C G T T G G A T C G A A C C T T C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C G T A G G A T C G A T C G T A G C A T G C T T G C A T C C T T C C T A G C T A G C T T G G A T G C T A C C A T G G A T G C A T G G T T G C T A G G T A C G T A C C T A C C T A C C T T G G T A C C A T G C A T C G T A C C A A C C T T G G T A G C T A G G A T G C T T C C A T C C A T C G A A G G A A G C T A G C T A G C T T G C T T G C A T C C A T G C A T G G T T G C A T G G T A C G A A C C T A C C T T C G T A G G A A C G T T C G T T C C T A G C A T G C T A G C T A G C T T G G A T G C A A C G T A C G T A G C T T C G T T C C T T G G T T G C T T C G A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A G G A T C C A A C G A T C G A T C G A A G G A T C G A T G C T A C C A A G C T A G C T A G G T A G G A A G C A A G C A T C C T A G G A A G G A T C C T A G C T A C C A T C C T T G C A T C G T T G G A A G C T T G G T T G C T A G G A A C G T A G C T T G C A A C G A A C C T A G G T A G C A A G C A A C G T +A C C T A G G A T G G T T C C T A C C T T C G A A G G A A C G A A C G A A G G A T C C T T G C T T G G A A G G A T C C T A G G T A C C A T G C A T G C T A G C T T G G T T C C T T C C A T C G T T C C T T G G T A G C A T G C T A C C A A G G A A G C A T G C A A C G T A G C T A C C T T C G T A G G T A G G T T G C A T C C T A G C A T C C A A C C T T C C T T G G A A G C T A C C A T C G T T C G T A G G T T G C A A C G A T C G A T G C A A C C T A G C T A G C T T G C A A G C T A G C T A G G T T G G T A G G T T G G T T G C T A C G T A G G A T G G A A C G A A G G T T C C A A C G A T G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T A G C A A G C A A G G T A C G T A C G A T G C T A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G C A A C G T T G C A T C C T A C C T A G C A A C C A A G G T A C G A T G G A A C C T A G G T A G C A A C G T A C C T A G G T A G C A T C G T T C G A T G G T A C C T T G C T T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C A T G G A T C C A A C C A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A A C G T T G C A T G G A T C C T A G C T A G G T T G C T T G C A A G G T A C C T T G C A T G C A T C C T T C G A T G G T A G G A A G C T A G C A T C G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T C G T A C G A A C G T A C G T A C C A A G G T A G C A T C C T A C C A T G C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A C C A A G C A A G C T T C G A A G G A T C G T A C C A T G C T T C G A T C C T A C G A T G G A A G C T T C G A A C C A A G G A A C G T A C C T T C C T T C C A T G G A A C G T T G G T T G C A A G C T T C G T A G G A T G G A A C G T A G C A T G C T T G C A T C C T A C G T A G C T A G G A A G G A T G C T A C C A A C G T T G C T T C C T A C C T A G G T A C G T T C G A T G C A T G C T A G C T T C C T T G C A T G G T A C C A A C C T A G G A A G C T A C C T A C G T A C C T T C G A T C G A A G G A A G C T A G C A A G C T A C C T A G C A A C C A T G C A T G C T T G G A T G G T A G G A T G C A T G G A T G G T A G G A T G G T T C C T T G C A A C G T T G G A A G C T A G G T T G G T T G G A A G C T T C C T A G C T A G G T T C C T T G G T A C C T T C G T A G C T A G G A A C G A A C C T A C C A T C C A A G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G A T C G A A G G A T C G A A C C A A C G A T G G T T G C T A C G A T G C A T G G A A C G A A C C T A G C T A C C A A G G T A C C T A C G T T G G A A G C T T G C T T G C T A G C A A C G T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T BOR_9536 # subpop. label: 4 (internally 4) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 1 1 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 2 2 2 1 2 2 1 1 2 1 2 1 1 2 1 2 1 2 2 1 2 1 2 1 2 1 2 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 2 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C A A C C T T C C T T C G T A G C T A C C T A C C T A C G T T C C A T C G A T G C T A G C A T G G T A C C A T G C T A G C T A C G T A G C T A C C T A C G A T G C T T G C A A G G T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRA_MN006 # subpop. label: 5 (internally 5) -2 2 2 1 2 1 1 2 2 1 2 2 1 1 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 1 1 2 1 2 2 2 1 2 1 1 1 1 1 1 2 2 2 1 2 1 2 2 2 1 2 2 1 2 2 2 1 2 1 2 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 1 1 2 1 2 1 1 1 2 2 2 2 1 2 2 1 1 1 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 1 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 2 1 2 2 1 1 2 2 1 2 1 2 2 2 1 1 2 2 2 2 2 2 1 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 1 2 1 1 1 2 2 1 1 2 1 1 2 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 1 2 1 2 2 2 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C A A C C A T G C T A C G A A C G T T G G T A C G T T C C T A C G A T G C A A G C A A G G A T C C T A C G A T G C T A G C A A C C A T C G A A G G T T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G G A A G C A T G G T T C C A T G C A A C G T A G C T T C C T A C C T A G C A A C C A T C G T A C C T T G G T A C C A A G G T T G G T A C G T T C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T T C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A A C G T T G C A T G G A T C C T T C C T A G G T A C G T A G G A A G G A A G C A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T G C A A G C T A C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C T A G G A T C C T T C G T T G C T A C G T A G G T T G C A T G G T T G G A T G C A T C C T T G C T A G G A A C G A T C C T A C C T A G C A T G G T T C C T T G G A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G A A C G A A G G T A G C T A C C T T G C A T G C A A C C A A G G T T C C T A G G A T G G T T G C A A C C A A C C T T G G A T C G A A G G T A G C T T C C T A G C A T G C T A C C T A G C T T C C T T G G A T G C T A C C T A G C T A G G T T C G T A C C T A G C A T G G T A G C T A G G A A C G A A C C T T C C A T C G A A G C T A C C T A G C T A C C T T C C A T C G A T G C T T G G A T G G T A C C A T G C T T G C T A G G T A G G A T G C T A C C A T C C T T G C A A G G T T C C A T C C T A C C T A G C T A G C A A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C T A G G T T C G T A G C T A C C T T G C A A G G T T G C A A C C A A C C A T C C T T G C A A G G A A G G A T G C A T G G T A G C A T C C A A G G A A C C T T G G A T C C A T C C T T G G A A C G A T G C T A C C T T G C T A G C A A G G A A G C T T G C A A C G T T G C A A G C T T C C A A G G T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G G A A C C T A G C T T C G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T C C T A G C T A G C T A G G T T G G T T G G T T G G T A G G T A G C A T G C T T G C A T C G T A G C T A C C A A C G A T G C T A G G A A G G T T G G T T G C A A C C A T G C T A C C A A C G T T G G T A C G T A C C T A C G A T G C A A G C T A G G T A C G T A C G A T G C T A G C A A G C T T C C A A G G A T C C A T C C T T G G T T C C T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A T G G T A C C T A C C T T G G A A G C A A G G A T G C A A G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C C A A G G A T C G T T C C A A C G A A G G A A C C A A G G T T C C A A G C A T G C T T G C T A G G A A G G T A G C A A C G T T G G T T G G A T C C T A C C T A G G T A C C T T G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G G A A C C T A G C T T G G T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G G T A C G A A G C T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G T T G C T A C G A T C C T A G G A A C G T A C C T T G C A T C C A T G G A A C G T A G G T A G C A A G C T A C C A A G C A T G G T T G G A T C G A T G C A A G G A A C C T T C G T T G C T A C G T A G G T T G G T T G C T T G G A T G C A T G G T T G C T A G G A A C G A T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C G T T C C T T G G A A G C T A G G T A C G T A C C A T C C T T C G A A C G A A G C T T C C T T C C T T G C T A G C T A C C A T G C A A G G T T G G A T G G T A C G T T G C A T G C T T G G T A C G A A C G T T G C T T C C T A G C A T G C T A C C T A C G T T G G A T G C T T G C A A C G T T G G T A G G T T C G T A G C T A G G A T G C T A G C T A G G A A G C A A G C T T C C A T C G T A G C A A C C T A C G T A C G T A C C A T C C A T C C T T G G A T G G T A C C A T G C T T G C T A C G T A G C T T C C T A C C A T G C T A G G A A G C T A C C T A G C T A C C T A C C T T G C T T G G T T C C A A G C T T G G T T G 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T G C T T G G A A C C T T G C T A C C A T G C T A C C A A G G A A G C T T G C A A C G T T G C A A G C T T C C A A G G T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G G A A C C T A G G T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T C C T A G C T A G C T A G G T T G G T T G G T T G G T A G G T A G C T A G C T T C C A T C G T A G G T A C C A A C G A T G G T A G G A A G G T T G G T T G C A A C C A T G C T A C G A A C G T T G G T A C G T T C C T A C G A T G C A A G C A A G G A T C C T A C G A T G C T A G C A A C C T T C G A A G G T T C C A T C G T T G G T T C C T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G A A C G T A G C T T C C T T C C T A G C A A C C A A C G T A C C T T G G T A G C T A G C T A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T C G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G C T T G C T T G G A A C G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T A C C T A G C A A G C T A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G G T A C G A A G C T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A A G C A T C C A A C C T A G G A T G G A A G C T A C G A T C C T A G G A T C C T A G C T T C G A A C C T A G G T A C G T A G G T A G C A A G C T A C G T A C G A T G G T T C G T T C G T T C G A T G G A T C C T T C G T T C C T A C G T A G G A T G C A T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G A A C C T A C C T A C C T T C C A T C C T T C G A A G C A A G G T A G C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T A C G A A C G T T G C T T C C T A G C A T G C T A G C A A C C T T C C T T G C A T G C T A C C T A G C T A G G T T C G T A C C T A G C A T C G T A G C A T G G A A G C A A G C T T C C A T C G T A G C T A C C T A C G T A C G T A C C A T C C A T C C T A G C A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C C T A G G T A G C T A G C T T G C A A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C T A G G T A C G T A G G T A G G A T G C T A G G T A G G A A C G A A G G T T G C T T C C T T G G T T C G A T G C A T G G T A G C A T C C A A G C T A C C T T G G T A G C A T C G A T G C T A G G A T G C T A C C T T G C T A G C A A G G A A G C T T G C T A C G T T G C A A C C T T C G A A G G T A G G T T C C A T C C T A G C T T C C A T G C A T C G A T G G T A G C T A G C A A G G T T G G T A G C T T G C A A G C A A G C T T G C A A G C T A G C A A C C A T C C T A G C T A G C T A G G T T G G T T G G T T G G T A G G T A G C T A G C T T C C A T C G T A G G T A C C A A C G A T G G T A G G A A G G T T G G T T G C A A C C A T G C T A C G A A C G T T G G T A C G T T C C T A C G A T G C A A G C A A G G A T C C T A C G A T G C T A G C A A C C T T C G A A G G T T C C A T C G T T G G T T C C T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G A A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G G T T G G T T G C T A G C T T C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T A C C A A G G A T G G A A C C A A C C A T C G A A C C A A G C T A C C T A G G A T G G T T G C T T G G A A C G T A G C A T C C A A G G A T G G A T C C T A C C T A G C T A C C T T G C A A G G A A G G A T G C T T C C A T C C T A C G T T C G A A G C A A G C T A C C A T G C A T G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C T T C C T T G G T A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C G A T C G A T G C A A G G A A C C T T C G T T G C T A C G T A G G T T G G T T G C T T G G A T G C A T G G T T G C T A G G A A C G A T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C G A T C C T T G G A A G C T A G G T A C G T A C C A T C C T T C G A A C G A A G C T T C C T T C C T T G C T A G C T A C C A T G C A A G G T A G G A T G G T A C G T A C C A 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C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A A C C T T C G T T G C T A C G T A G C A T G C T A C C T T G G T T G C T A C C T T G C T A G G T A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G T A C C T A C C T A C G T A C C A T C C T T G G A A C G A A G C T A C C T A G C T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T C C A A G G T T G G A T C G A A C G T T G C T T C C A A G C A T C C T A C C T A G G T T G G A T G C A A G C A T C C T A G C T A G G T T C G T A C C T A G G T T C G T A G C T A G G A A G C T A G C T A C C A T C G A A C C T A C C T A C C T A C C T T C C A T C C A T G C T T G G A T G C A A G C A T G C T A G C T A G G T A G G A T G C T A C C A T C C T T G C A A G G T A C C T A G C A A C C T A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G C T A C C T A G C A A G C T A C C A A G G T A C C T BRA_MN012 # subpop. label: 5 (internally 5) 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C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C G T A G G A T G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T T C C A T C C A A C G A A G C T A G G T A C C T A G C A T G C T T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A G C T T G C T T C C T T C C T A C G T T C G T A C G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C G A A C G A T G C T T G C T A G C A A C C T T C C T T G 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A G C T A G C T A G C T T G C T A G G T T G G T A G G T T G G T T G C T T G G T A G G T A G C A T G C T T C C A A G G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A C G T A G G T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C T A G C T T C C A A G G A T C C A T C C T T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A T G G T A C C T A C C T T G G A A G C A A G G A T G C A A G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C C A A G C T T C G T T C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A G G A A G G T A G C A A C G T T G G T T G G A T C C T A C C T A G G T A C C T T G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G C A T G C A T C C A A G C A A C C T A C C A A G G T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C T T C C T T G G T A C C A A G C T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A A G C A T C C A A C C T A G G A T G G A A G C T A C G A T C C T A G G A T C C T A G C T T C G A A C C T A G G T A C G T A G G T A G C A A G C T A C G T A C G A T G G T T C G T T C G T T C G A T G G A T C C T T C G T T C C T A C G T A G G A T G C A T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G A A C C T A C C T A C C T T C C A T C C T T C G A A G C A A G G T A G C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T A C G A A C G T T G C T T C C T A G C A T G C T A G C A A C C T T C C T T G C A T G C T A C C T A G C T A G G T T C G T A C C T A G C A T C G T A G C A T G G A A G C A A G C T T C C A A C G T T C C T A C C T A C C T A C C T T C G A T C G A T G C A T C G A T G G T A C C A T G C T A G C T A G G T A G G A T G C T A C C A T C C T T G C A A G G T A C C T A G C A A C C T A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G C T A C C T A G C A A G C T A C C A A G G T A C C T +A G C T A G G T A C G T A G G T A G G A T G C T A G G T A G G A A C G A A G G T T G C T T C C T T G G T T C G A T G C A T G G T A G C A T C C A A G C T A C C T T G G T A G C A T C G A T G C T T C G T T C C T T C C A T G C T A C C A A C C A T G G A T G G A A C G T T G C A A C C T T C G A T G G T A G C T A C C A T C C T A G C T T C C A T G C A T C G A T G G T A G C T A G C A A G G T T G G T A G C T T G C A A G C A A G C T T G C A A G C T A G C A A C C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T C C T T G C A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T C C T A C G A A C G T A G G T A C G T A C C T A C G A T G C T A G C T A G G T A G C T A C G A T G C T A G C A A G C T T C C A A G G A T C C A T C G A T G G T T C G T T C G T T G C A T G G T T G C T T C G T A C G A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A T G G T A C C T A C C T T G G A A G C A A G G A T G C A A G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C C A A G C T T C G T T C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A G G A A G G T A G C A A C G T T G G T T G G A T C C T A C C T A G G T A C C T T G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G C A T G C A T C C A A G C A A C C T A C C A A G G T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C T T C C T T G G T A C C A A G C T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A A G C A T C C A A C C T A G G A T G G A A G C T A C G A T C C T A G G A T C C T A G C T T C G A A C C T A G G T A C G T A G G T A G C A A G C T A C G T A C G A T G G T T C G T T C G T T C G A T G G A T C C T T C G T T C C T A C G T A G G A T G C A T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G A A C C T A C C T A C C T T C C A T C C T T C G A A G C A A G G T A C C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T A C G A A C G T T G C T T C C T A G C A T G C T A G C A A C C T T C C T T G C A T G C T A C C T A G C T A G G T T C G T A C C T A G C A T C G T A G C A T G G A A G C A A G C T T C C A A C G T T C C T A C C T A C C T A C C T T C G A T C G A T G C A T C G A T G G T A C C A T G C T A G C T A G G T A G G A T G C T A C C A T C C T T G C A A G G T A C C T A G C A A C C T A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G C T A C C T A G C A A G C T A C C A A G G T A C C T BRA_MN015 # subpop. label: 5 (internally 5) -2 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 2 1 1 1 2 2 2 2 2 1 2 2 2 1 1 2 1 1 1 2 2 1 2 1 2 2 2 1 1 2 2 1 2 1 2 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 1 2 1 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 2 2 2 1 2 2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 1 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 2 2 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 1 2 1 1 2 2 2 1 1 2 1 2 1 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 1 1 1 2 2 1 2 2 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2 2 +A G C T A G G T A C G T A G G T A G G A T G C T A G G T A G G A A C G A A G G T T G C T T C C T T G G T T C G A T G C A T G G T A G C A T C C A A G C T A C C T T G G T A G C A T C G A T G C T A G G T T G C T A C C A T G C T A G C A A G C A A G C T T G C T A C G T T G C A A C C T T C G A T G G A T G G T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G C T A G C A A G G T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C C T T G C T A G G T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T G C T T C C A A C G T A G G T A C C A A C G A T G C T A C C T A G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A G G T A C C T A C G A T G C A A G C T A G G A A C C T A C G A T G C T A G C A A C C T T C G A A G G T T C C A T C G T T G G T T C C T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G A A C G T A G C T T C C T T G C T A G C A A C C A T C G T A C C T T G G T A G G T T G G T T G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T A C C A A G G A T G G A A C C A A C C A A C G A A C C T A G G T A C C T A G C A T G C A T G C T A C G A A G G T A G C A T C G T T G C T T G G A T C C T A G C T A G G T A C G T A G C A A G C T A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T A C G T A G G T T G G T T G C T T G G A T G C A T C C A A G G T A G G T A C G T A C C A T G C T A G C A A G C T A G C T A G C A T C G T A C C A A G C T T G C T A G C A T G G T T G C T A C C A T C C T T C G A A G C T T G C T A G C T A G G T A C C T T G G A A C C A A C G T T C C T T G C A T G G A A G G A A C C A A C G T T C G T A G G T T G G T A G C T T C C A A G C A T C C T A C C T A G C A T G C T T G C T T G C T A C C T A G C T A G G T T C G T T C C T T G C A T G G T A G C T A G G A A G G A A C C T T C C A T C G T A G C T A C C T A G C T A C C T T C C A T C C A T G C T T G G A T G C A A G C A T G C T A G C T A G G T A G G A T C C T A C G T A G C T A G G T A G G T T C C T A G C T A C C T A G C T T G C T A G G T T G C A A G C T T G G T T G C T A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T T G G A T G C T T G C T A C C T T G C T A G G T A G C T A C G A A G G T T G C T T G C A A C G T T C G A T G C T A C C T A C C T T C G A T G C T A C C T T G G A A C C A T G C T T C G T T C G T T G C T A C C T T G C T A C C A A G G A A G C A T G C A A C G T T G C A A C C T T C C A T G G T A G G A T C G A T C C T A G C A T C C A T G C T T C C T T G G T A G C T A G C T A G G T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C C T T G C T A G G T A G C T A G G T T G G T A G G T T G G A A G G T A C C T T G C T T C C A T C G T A G G T A C C A A C G A T G G T A G G A T G G T T G G T T G C T A C C A T G C T A C G A A G G T T G G T A C G T T C C T A C G A T G C A A G C A A G G A T C C A A C C A T G C T A G C A A C C A T C G A A G G T T C C A T C G T T G G T T C C T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A T G G T A C C T T C C T T G G A A G C A A G G A T G C A A G G T A C G T T G C T A C G T A G C A A C G T A G 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G A A C G A T C C T T G G A A G C T A G G T A C G T T C G A T C G A T G G A A C G A A G C T T C C T T C C T T G C T A G C T A C C A T G C A A G G T A G G A T G G T A C G T A C C A A C C T T G G A T C G A A G G T T G C T T C C T A G C A T G C T A G C T A C G T T C C T T G G T T G C T A C C T A G C T A G G T T C G T A G C T A G G A T G G T A G C T A G G A A G C A A C C T T C C T T C G T A G C T A C C T A C G T A C G T T C C A T C C A T C C T T G G A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C C T A G G T A G C T A G C T T C C T A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T BRA_MN016 # subpop. label: 5 (internally 5) -2 2 2 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 1 2 1 2 1 1 1 1 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 2 2 1 2 1 2 1 1 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 1 2 1 2 1 1 1 1 2 1 1 2 2 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 2 2 2 1 2 2 2 2 1 2 2 2 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T G C A A G G T T C C T A G C T A C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C A T C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C G A A C G A T G C T T G C T A G C A A C C T T C C T T G C A A G C T A G C A T C C A T C G A A C G T A G G T A G C A A G C T A C C A A C G A T G G T T G G T A G G A T G C T A C G A T C C T T C G T A C C T T C G T A G C T A G C T A G C T T G G A T G C A T G C T T G C T A G G A A C G T T C C T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T G G A A C G A A G C T A C C T A G C T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A C G T T G C A A G G A A C G T A C C T T C C T A G G T A C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T A G C T A G G T A G C T A G G A A C G A A C C T T C C A T G G A A G G T A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T A G C T A G G T A G G A T G C T A G C A T G C T A G G A A G C T A C C T A G C T A C C T A C C T T G C T A G G T T C G A A G G T T G C T T C C T A G C T A C C T A G G T T G C A A G C A A C C T A G G A A G C T A G C A A C G T +A G C T A G G T A C G T A G G T A G G A T G C T A G G T A G G A A C G A A G G T T G C T T C C T T G G T T C G A T G C A T G G T A G C A T C C A A G C T A C C T T G G T A G C A T C G A T G C T T C G T T C C T T C C A T G C T A C C A A C C A T G G A T G G A A C G T T G C A A C C T T C G A T G G A T G C T A C C A T C C T A G C A T G C A T G C T T C C T T G G T A G C T A G C A A G G T T G G T A G C T T G C A A G C A A G G A T G C A A C C T A G C T A C C T T G C T A G G T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T C C T T G C A T C G T A G G T A C C A A C G A T G G T A G G A T G C T T G C T T G C A A G C A T G C T A C G A A C G T A C G T A G G T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C T A G C T T C C A A G G A T C C A T C C T T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G C T A G C T A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T T C C A T C C A A C G A A G C T A G G T A C C T A G C A T G C T T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T A C C T A G C A A G C T A G C T T G C T T C C T T C C T A C G T T C G T A C G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C G A A C G A T G C T T G C T A G G A T C C T A G G A T C C A A C C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C G A T G G A T C C T A G G A T G C A A G G A A C C T T C G T T G C T A C G T A G C A T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C G T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G T A C C T A C C T A C C T T C C A T C C T T C G A A G C A A G G T A G C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G C A A G G A A C G T A C C T T C C T A G G T A C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T T G C T T G G T A G C T A G G A A G C A A C C T T C C T T C G T T G C T A C C T A C C T A C G T T C C A T C C A T G C T T G G A T G C T A G C A T G C T A C G T A C G T A G G A A G C T A C C A T G C T A G C A A G C T A C C T A G C A A C C A T C G T T C C T A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRA_MN017 # subpop. label: 5 (internally 5) -2 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 2 1 1 1 2 2 2 2 2 1 2 2 2 1 1 2 1 1 1 2 2 1 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 1 1 1 2 2 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 2 2 2 1 2 2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 1 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 1 2 1 2 2 2 2 1 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 2 2 1 2 2 2 2 2 2 2 2 2 1 1 2 1 1 1 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 1 2 2 2 1 1 1 2 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 1 1 2 2 1 2 1 2 1 2 2 1 1 2 1 1 2 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 1 2 2 2 1 1 1 1 2 2 2 2 2 2 1 2 1 2 1 1 1 1 1 2 2 1 2 1 1 2 1 1 1 1 2 1 2 1 2 1 1 2 2 1 1 1 2 1 2 2 1 1 2 1 2 1 2 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C A T G C A A G G T A G G A T G G T A C G T A C C A A C C T T G G A T C G A A G G T T G C T T C C T A G C A T G C T A C C T A C G T T C C T T G G T T G C T A C C T A G C T A G G T T C G T T G C T A G G A T G C T A G C T A G C A A G G A A C C T A C C A T C G T T G C A A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T A G C T A G G T A G G A T C C T A C C A T G C T A G G A A G C T A C C T A G C T A C C T A C C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRA_MN018 # subpop. label: 5 (internally 5) -2 2 2 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 1 2 1 2 1 1 1 1 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 2 2 1 2 1 2 1 1 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 2 1 2 1 2 1 1 1 1 2 1 1 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 1 2 1 2 1 2 1 1 2 1 1 1 2 1 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 2 2 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 1 2 2 2 1 2 2 1 2 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T G C T T C G T A C G A A C G A A G C A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G C A A C G T A G C A T C C T A C C T A G C A A C C A T C G T A C C T T G G T A G C T A G G A T G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G T T C C A A C C A A C G A A C C T A G G T A C C T A G C A T G C T T G C T A G G A A G G T A G C A A C G A T G G T T G G A T C C T A C C T A G C T A C C T A G C A A G G A A G C T T G G T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C T T G G T T C G A T C C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G T T G G T A C C T T C C A A G G T A C G A T C C T A C C A T G C T A G C T A G C A A G G A A G C T T C C T T G C A A C G A A G C T A C C A A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A C G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C G A T G G A T G G T A G G A T G C T A C G A T C C T T C G T A C C T T C G T A G C T A G C T A G C T T G G A T G C A T G C T T G C T A G G A A C G T T C C T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G A A G C A A G G A A G C T T G C T T C C T A G C A A C C A T G C A A G G A T G C A T C G A A G G A A C C T A C C T T G C A A G G A A C G T A C C T T C C T A G G T A C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T A G C T T G C T A G C T A G G A A C G A A C C T T C C A T G G A A G G T A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T A G C T A G G T A G G A T G C T A C C A T G C T A G G A A G C T A C C T A G C T A C C A A C C T T G C T A G G T T C C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C T A G G T A C G T A G G T A G G A T G C T A G G T A G G A A C G A A G G T T G C T T C C T T G G T T C G A T G C A T G G T A G C A T C C A A C C T A C C T A G C T A G C A T G C A T G G T T C C T T G C T A C C T T G C T A C C A A C G A A G C T T G C A A C G T T G C A A C C T T C C A T G G T T G C T T G C A T C C T A G C A T C C A T G C T T C C T T G G T A G G A A C G T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T C C T A G C T A G C T A G G T T G G T T G G T T G G T A G G T A G G T T G C T T C C A T C G T A G G T A C C A A C G A T G G T A G G A A G G T T G G T T G C A A C C A T C C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A C C T A G G A A C G T A C G A T G C A A G C A A C C T T C G A A G G T T C C A T C G T T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A T G G T A C C T A C C A T G G A A G C A A G G A T G C A A G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C C A A G C T T C G T T C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A G G A A G G T A G C A A C G T T G G T T G G A T C C T A C C T A G G T A C C T T G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G G T A C G A A G C T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T T C G T A G C A A G G A T G C T T C C T T G C A T C C T A G G T A C G T A G G T A C C A A G G T T C C T A G C A T G G A T C G A T C G A T G C A A G G A A C C T T C G T T G C T A C G T A G G T T G G T T G C T T G G A T G C A T G G T T G C T A G G A A C G A T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C G A T C C T T G G A A G C T A C C T A C G T A C C A T C C T T G G A A C G A A G C T A C C T A G C T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A C G T T G C A A G G A A C G T A C C T T C C T A G G T A C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T T G C T T G G T A G C A A G G A A G C T T C C T A C G A T C G A A G G T A C C T A C C T A C G T A C C A T C C A T G C T A G C A T G C T A C C A T G C T A G C T A C G T A G C T A C C T A G C A T G C T A G G A A G C T A C C T A G C T A C C T A G G T A G C T T G G T T G C A A G C T T G G T T G C T A G C A A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRA_MN021 # subpop. label: 5 (internally 5) -2 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 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G T T G C T A G C T T G C A A G C A A G G A T G C A A G C T A G C T A G C T T G C T A G C T A G C T A G G T T G G T A G G T T G G A T G G T A C C T T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A G G T A C C T A C G A T C C A A G G T A G G A A C G T A C G A T G C T A G C A A C C A T C C A A G G A T C C A T C G A T G G T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A C C A T G G A A C G T A G C T T C C T T C C T A G C A A C C A T C G T A G C T T G G T A G G T T G G T T G C T A G C T T C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A C G T A C G A A G C T T C G T A C C A A C C A A C G A A C C T A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C A T C G T T G C T T G G A T C C T A G C T A G G T A C C T A G C A A G C T A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C A A C G A A C G T A G C T T G G A T G G T A G C A A C C A T G C T T C G A T G G T A C C T T C C A A G G T A C G A T C C T A C C A T G C T A G C T A G C A T C G A A G C A A C C T T G G T A C G A A G G T A C C T A C G T A G C A T G C T T C G A A G C A A G G T A C C A A G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T T G C T T C G T A G C T A G C T A G C T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C A A G G A A C C T T G G A T C G A A C G A T C C T A G G A A G C T A G G T T C C T A C C A T C C A T C G A A C G A A G G T A C C T T C C T T G C T T G C A A C C A T G C A T G G T T G C A T G G A A C G A A C C A A G G T T C G T A G G T T G G T A G C T T C C A A C G T T C C T A G C T A G C A T G C T T G C T T G C T A C C T A G C T A G G T T C G T T C C T T G C A T G G T A G C T A G G A A G G A A C C T T C C T T C G T A G C T A C C T A C C T A C G T T C C A T C C A T C C T T G G A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C C T A G G T A G C T A G C T T C C T A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T T G C T A G C T T G C T A G C T A G C T A C C T A G G T T G C T T C C T T G G T T C G A T G C A A C C T A G C A T C C A T G C T A C C T A G C T A G C T T G C A T G G T T C G T T G C T A C C T T G C T A C C A A G G A A G C T T G C T A C G T T G C A A C C T T C G A A G G T A G G T T C C A T C C A A G C T T C C A T G C A T C G A T G G T A G C T A G C A A G G T T G G T A G C T T G C A A G C T A G C T T G C A A G C T A G C T A G C T T G C T A G G T A G C T A G G T T C G T T G C T T G G T A G G T A G C A T G C T T C C A A C G T A G G T A C C A A C G A T G C T A C C T A G G T T G C T T G C A A G C A T C C T A C G A A G G T T G G T A C G T A C C T A C G A T G C A A G C A A G G A A C C A A C C A T G C T A G C A A C C A T C G A A G G T T C C A T C G T T G G T T C C T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G A A C G T A G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G A A G G T A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A G G T A C C A A G G A T G G A A G C A A C C A T C G A A C C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G C A T G C T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T A C C T T G C A A C G A A G G T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G C A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G A A C C A A G C T A C C T A G C A T G C A T C C T A G G A T G C A T G G A T C C T T C C T T G C T T C G T A G G T T G G T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C C A T C C T A G G T A G C T A G G T A C G T T C G A T C C T T C G A A C G A A G C T T C C A A G C T T G C T T G G A T C C A T G C A T G G T T G C A T G G T A G G A T C C T A C C T T C G T A G G A A C G T A G C T T C C A A G C A T C C T A C C T A G C T T C C T T G G A A G C T A C C T A G C T A G G T T C G T A C C T A G C A T G C T A G C T A G G A A G C A A G C T T C C A T C G T T C C T A C C T A C C T A C C T T C C A T C C A T G C T T G G A T G C A A G C A T G C T A G C T A G G T A G G A T C C T A C G T A G C T A G G T A G G T T C C T A G C T A C C T A G C T T G C T A G G T T G C A A G C T T G G T T G C T A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRA_MN022 # subpop. label: 5 (internally 5) -2 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 2 1 1 1 2 2 2 2 2 1 2 2 2 1 1 2 1 1 1 2 2 1 2 1 2 2 2 1 1 2 2 1 2 1 2 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 1 2 1 1 2 2 2 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 2 1 1 2 2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 1 1 1 2 1 2 2 2 1 1 2 1 2 2 2 2 1 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 1 2 2 2 1 2 1 2 1 2 2 1 1 2 2 2 2 2 1 2 1 1 2 1 1 1 2 2 1 2 2 1 2 1 2 1 1 1 1 2 1 2 2 2 1 1 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 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T C G T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G T A C C T A C C T A C G T A C C A T C C T T G G A A C G A A G C T A C C T A G C T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A C G T T G C A A G G A A C G T A C C T T C C T A G G T A C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T T G C T T G G T A G C T A G G A A C G A A C C T T C C A T G G A A G G T A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T A G C T A G G T A G G A A G C T A C C A T G C T A G G A A G C T A C C T A G C T A C C T A C C T T G C T A G G T T C C A A G C T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRA_MN023 # subpop. label: 5 (internally 5) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 1 2 1 1 1 1 2 2 2 1 2 1 1 2 1 1 1 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 1 2 2 1 2 1 2 2 1 2 1 1 2 2 1 1 2 2 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 1 1 1 2 1 2 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T A C C T A G G A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A C C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A T G C T A C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T A C C T T G C A A C G A A G G T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C T A G G A T C C T T G C A T C C T A G G T A G C T A G C T A G C T A G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C C A T C C T A G G T A C C T A C C T A C G T A C C A T C C T T C G A A C G A A G G A A C G T T G C T T G C T T G C A A C C A T G C A A G C A T G G A T G G T T G C A A G G A A C C T T G G T A G G A A C G T T C C T T C C A A G C A T G G T A G C T A C G A T G G A T G G A A G C T A C C T A G C T A G G T T C G T A C C T A G C A T C G T A G C T A G G A A G C T A G C T T C C T T C G T T G C T A C C T A C C T A C G T T C C A T C G A T G C T T G G A T G C T A G C A T G C T A G C T A C G T A G C T T C C T A C G T A G C A T G G A A G C A T C C A A C C T A C G T T C C T T G C T T C G T T C C A A G C A T G G A T G G A T G G A A C G A T G C T T G G T A G C A A C C T A G G A A G G T T G C A A G C A BRM_000002 # subpop. label: 6 (internally 6) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 1 1 2 1 1 1 2 1 1 1 2 2 2 2 1 1 2 2 1 2 1 2 2 2 1 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 1 1 2 2 1 2 1 2 2 2 2 2 1 2 2 1 1 2 2 2 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 1 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 1 2 1 2 2 1 1 2 2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 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A G G T A G C A A G C T A C C A A C G A T G G A T C C T A G G A T G C A A G G A A C C T T C G T T G C T A C G T A G C A T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C G T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C T T C G A A G G A A G C T A C C T T C C T T G C T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T A C G A T C G T T G C T T C C T A G C A T G G T A G C T A C G T T C G T T G G A A G C T A C C T A G C T A G G T T C G T A C C T T G C T T G G T A G C T A G C A A C G A A C C T T C C A T C G T T G C A A G C T A C C T A C G T T C C A T C C A T G C T T G G A T G C T A G C A T G G T A G C T A C G T A G C T A C C T A C G T A G C T T G C A A G G T A C C T A G C T A C C T A G C T A C C T T G G T A C C T A G C T T G G T T G C T A G C T A C C T A G G T A G C T A C C T A G C A A G C T A C C A A G G T A C C T BRM_000003 # subpop. label: 6 (internally 6) -2 2 2 1 2 1 1 2 2 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A A C G T T G C T A G C T A G C T A C C T T C C T A G C T T G G A T G G T A G G A T G C T T G G A A G G A A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A G G T A C G T A G G T A C C A A C C T A G G A A C C T A G G A A C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G C A T G G A A C G T A G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A C G T A C G A A G C T T C G T A C C A A C C A T C G A A C C A A G G T T C C A A C C A A G G T T G C T A G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G G A A G C A T G C T T G C T T C C T T C G T T C G A A C G A A G C T A C C 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T A G G T T C G T A C C T T G C T A G C A A G C T A G G A A G C A A C C T T C C T T C G T A G C T A C C T A C C T A C C T T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A G G T A G C A A C C T A G C T T C C T T C G A A G G A T C C A A C C T A C G T A G C T T G C T A G G T T G C A A G C T T G G T T G C T T G C A A C C T A G G T A G G T A C C T A C C T A G C T A G C A A C G T A C C T +A G C A A C G T A C C T T C C A T G G A T G C T A G G T A G C T A C C A A G G A A G G A A G C A A C G A T G G A T G G A T G G T A G C A T G G A T C C T A C C T T G G T T G C A T C G A T G C T A G G T T G C A A C C A T G C T A C C A A G G A A G C A T G C A A C G T T G C A A C C T T C G A T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A C C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A C C T A G C T T G C T A G G T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T G C T T C C A A G G A A G G T A C C A A C G A T G C T A C C T A G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A G G T A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A G C A A G C T T C C A A G G A T C C A T C G A T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T G C T T C C T A C C T A G C A A C C A T C G T A G C T T G G T A C G A A G C T A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T A C G A A G C T T G G A A G C A A C G A A C G A A C C T A G C T A C C T A G C A T G C A T G C T A C G A A G G T A G C A T C C A A G C A T C G A T G C T A C C T A G G T A C G T A G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A C C A A C G A A C C A T G C T T G G A A G C A A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T T C C T A G G T A G C T A G C T A G C T A G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G A A C G A A G G A A C G T T G C T T G C T T G C A A C C A T G C A A G C A T G G A T G G T T G C A A G G A A C C T T G G T A G G A A C G T A C C T T C C T A G G T A C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T A C C T T G C T T G G T A G C T A G G A A C G A A C C T T C C A T G G A A G G T A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C A T G G A A G C A A C C T A G C T A C C A T C C T T G C T T C G T T C C A A G C A T G G A T G G A T G G A A C G A T G C T T G G T A G C A A C C T A G G A A G G T T G C A A G C A BRM_000006 # subpop. label: 6 (internally 6) -2 2 1 2 1 2 1 1 1 2 2 2 1 1 2 1 1 2 1 1 1 2 2 2 1 2 1 2 2 2 1 2 1 1 2 1 2 1 2 1 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 1 1 1 2 1 2 1 2 2 2 2 2 1 1 2 2 1 2 1 2 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 1 2 1 2 1 1 1 1 1 1 2 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 1 2 2 1 1 2 2 2 2 1 2 2 2 2 2 1 1 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 2 2 1 2 2 2 2 1 1 1 2 2 1 1 2 1 1 1 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 2 2 1 2 1 2 1 2 1 2 2 1 2 2 2 1 1 1 2 2 2 1 1 1 2 1 1 2 2 2 1 2 2 1 1 2 2 1 2 2 2 1 1 2 2 2 2 1 2 2 2 2 2 2 1 1 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T G G A T G C T T C C A T G G A T G C T T G G T A G G T T C C A A C C A T G C T T G C T T G G A A C G A T C G T T G G T A G C T T C C T T G G T A C C T A G G T A G C A T G C A T G G T T C C T T G C T A C C A T G C T A C C A A G C A A G C T T G C T A C G T T G C A A C C T T C G A T G G T A G C A A C C A T C C T A G C T A G G A A C C A T C G A T G G T A G C T A C C T A G C T T G G T A C G T A G C A A G C T A C G T T G C A A G C T A G C A A C C T T G C T A G G T A G C T A G G T T G G T T G G T T G G T A G G T A G C A T C C T T C C A T C G T A G G T A C C A A C G A T G C T A G G A A G G T T G G T T G C A A G C A T C C T A C G A A C G T A G G T A C G T A C C T A C G T A G C A A G C T A G G A A C G A A C G A T G C A A C C T A C C T T C G A A G G A T C C A T C G T T G G T T C G T T C C A T C G T A C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G T T C C A T G C T A C G T A G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G C A A G G A A G C T A G C T A C G A A G C T T G C A A G C A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C C A A G C T T C G A A C G A A C G A A G G A A C C A A G G T T C C A A G C A T G G T T G C T A G G A A G G T A G C A A C G T T G G T T G G A T C C T A C C T A G C T T G C T T G C A A G G T A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T T C C A T G C A T G G T T C C A T C C A A G C A A C C T A G C T A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C G A A G C T T C C T T G C A A C C A A G G T A C C T A G C T A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C G A A C G A T G C T T G C T A G G A T C C T A G G A T C C A A C C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C G A T G G T T G G T A G G A T G C T A C G A T C C T T C G T A C C T T C G T A G C T A G C T A G C T T G G A T G C A T G C T T G C T A G G A A C G T T C C T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C C T T C C A T C C T T C G A A G C A A G G T A G C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T T C G T A C C T T C C T T C C T A C C A T C C T A G C T T G C A T G G A T G C A T G C T A C G T T G G T T C G T T G G T A C C A A G G T A G C T A G C T T G C A A G C A A C C T T C C A T C G T A C C A A G C T A C C A A G C A T C C A A G G A A G C T A G G T T C C A A G C A T G C T T C C T T C G T T G G T A C C A A G C A T C C T T G G T A C C T A C C T A G C T A C G A A G G T A G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G G T A G C A A C G T +A G C T T C G T A C C T A G G A T G G A T C G A T G C T A C G T A C C A A G G A T G C T T G C A A C G T T C G A T G C T A C C T A C C A T C C A T G C T A C C T T G G T A C C A T G C T T G G A A G C T T G C T A C C T T G C T A C C A A C C A A G C A T G G A A C G T T G C A A G C T T C G A T G G T T G C T T G C A T C C T A G C T T G C A T G C A T C G A T G G T A G C A A G C T A G G T T G G T A G C T T G C A A G C A A G G A T G C A A C C T A G C A A G C T T G C T A G C T A G G T A G G T T C C T A G C A A G G A A C G A A C C A A C C A A C G A T G G A A G G T A C C A A C G A T G C T A G G A T G G T A G C T T G C A A C C A T C C T A C G A A G G T T G G T A G G T A C C T A C G A T G C A A G G T A G G T T G G T A C G A T G C T A G C A A C C T T C G A A G G T A G G A A C G T A C G T T G G T T G C T A G C A T G G T T G C T T C C T A G C A T G G A A G G A T C C A T C C T T G G A A C C A T C G T A G G A A C G A A G C T A G C A T C G T A G G T T G C T A C G A A C C A A C C T T G C A T C C A T C C A T G G T A C C T T G G T A C G T T G G A A G C T A G C T A C C T T G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A C G T A C C A A G C T T C G T T C C A A C G A A C G A A C C A A G C T A C C T A G C A T G C A T G C T A C G A A G G T A G C A T C C A A G C A T C G A T G C T T C C T A G G T A C G T A G C A A G G A A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G C A A C C T A G C T T G C T T C G A T C G A A C C T A C G A T C G A T G G T T G G A T G C T T C G T T G C T A C G A T G G A A C C T T C C T A G G T A C C T A C C A A G C T T G C T A C G A T G C T T C G T A G C T T C C T T G G T A C G A T G G T T G C T A G C A A C C A A G C A A C G A A G C T A C G A A C G T T G C T T C G A A C C T T G G A T G G A A G C A A C G A A C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C G A T G G A T C C T A G G A T G C A A G G A A C C T T C G T T G C T A C G T A G C A T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C G T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C G T T C G A A G G A A G C T A G C A T G G T T G G T A G G A T C G T T G C A A G G T T G G T T G C T T C C A A G C T A G G A T C G T A C G A T C G T T G C T T C C T A G C A T G G T A G C A A G C T T C G T T G C A T G C T A C C T A G C T A G G T T C G T A G C A A G C A T G C T A G C T A G C A A G C A A G C T T C C A T C G T T G G T A C C T A C C T A C G T T C C A T C G T T G C A T G G A T G C T A G C A T G G T A G C T A C G T A G C T A C C T A C G T A G C A T C C A A G G T A C C T A G C T A C C T A G G T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRM_000007 # subpop. label: 6 (internally 6) -2 1 2 2 2 2 1 2 2 2 2 2 1 1 2 2 2 1 2 2 1 1 2 2 2 2 2 1 2 2 2 2 2 1 1 1 2 2 1 2 1 2 1 2 1 1 2 2 1 2 1 1 1 2 1 1 1 2 2 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 1 2 1 2 1 1 2 2 1 2 2 1 2 1 2 1 1 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 1 2 1 1 2 1 1 2 1 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2 1 2 2 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 2 2 1 2 2 2 2 2 2 2 2 1 1 2 1 1 1 1 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 1 1 1 1 1 1 1 1 2 2 2 1 2 1 1 1 2 1 2 2 1 2 1 1 2 1 2 2 2 2 2 2 1 1 2 2 2 1 1 1 2 2 2 2 1 2 1 1 1 2 2 1 2 2 1 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 1 2 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 2 1 2 2 1 1 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 +A C C T A G G T A G C T T C C T A C C T T C C T A G C A A G C T A C G A A G G T T G G T T C C T T G G A T G G A T G C A A G G T A G C A T C C A A C G T A C C T A G C T A G C A T G C T T G G T T C C T T G C A A C C A T G C T A G C A A C C A A G C A T G G A A C G T T G C A A C C T T C C A T G G T T G C T T G C A T C C T A G C A T C C A T G C T T C C T T G G T A G C A A G C T A G C T T G G T A G C A T G C A A G C A A C G T T G C A A C C T A G C A A G C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A C G T A C C A T C C T T C C A T C G T A G G T A C C A A C G A T G G T A G G A T G G T T G G T T G C A A C C A T C C T A C G A T C G T A G G T A C G A A C C T A C G A A G G T A G C T A G G A A G G T A C G A T G C T A G C A A G C T T C C A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A G G A A G C A A C C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G C A A C G T A G C T T C C T A C C T A G C A A C C A T C G T A C C T T G G T A G C T A G G A T G C T A G C T A C C A T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G T T C C A A C G A A C G A A C C A A G C T A C C T A G G A T G G T T G C T T G G A A C G T A G C A T C C A A G G A T G G A T C C T A C C T A G C T A C C T A G C A A G C T A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C T T G C T T C G A T G G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C G A A G G T A C C T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C A T C C A A C C T T C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A A C G T A G G A T G C A A G G A T C C T T C G T T C C T A G G T A G G T T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T T G C T A G C T T G G A A C G T T C G A T C C A T C G A T C G A A G C T A C C T T G C T T C C T T G G T A C C A T G C A A G G T T G C A A G G A A G G A A G G A T G G T T C G T A G G A A C G T A C G T T C C A A G C A T G C T A C C T A G C A T G G A T G G A A G C T A C G T A G C T A G G T T C C T A G G T A G C T A G G T A G C T A G G A A G C A A C C T T C C T T C G T A G C T A C C T A C C T A C C T T C C A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G G A T G C A A G C T T C C T A G G T A G G T A C C T A G C T A C G T A G G T T G C T T G G T T G C A A G G T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A G G T A G C T T C C T A C C T T C G A A G C T A G C T A C C A A G G T T G G T T G C T T G G T T C G A T G C T A G G T A G C A T G C A A G C T A C C T A G C T A G C A A G C A T G G T T G C T T G C T A C C T T G C T A C C A A C G A A G C T T G C A A C G T T G C A A C C T T C G A T G G T T G C A T C C A T G C A A G C T T C C A A C C T T C C T T G G T A G C T A G G T T C G T T G G T A G C T T G C A A G C T T G G T A G C A A C C T A G C A A C C T T C C T A G G T A G C T A G G T T G G T T G C T T G G T A G G T A G G T T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T C C T T G C A A G C A T C C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A C C T A G G A A C G T A C G A T 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G G T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T A G C A A G C T A C C T A G C A A G G T T G G T A G G A T G C A A C G A T C C T T C G T A G C T A C G T A G G T T G C T A G G T T G G A T G C A T C C T T G C T A G G A A C G A T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C G A T C C T T G G A A G C T A C G T A C G T A C C A T C C T T C G A A C G A A G C T A C C T A G C T T G C T T G G A A G C A T G C A T G G T T G C A T G G A A C G A T G C A A C C T T C G T A G G A T C G T A C C T T C C T A G G T A G G T A G C T A C G T T C C T T G G T A G C T A C C T A G C T A G G T T C C T A G C T T G C A T G G T A G C T A G C A A G C T A G C T T C C A T C G T T G C A A C C T A C C T T C C T T C G A T C G A T G C T T G G A T G G T A C C A T G G T A G C T A C G T A G G A T G C T A C C A T C C T T G C A A G G T A C C T A G C T A C C T A G C T T 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G C T T C G T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G C A A C G T T G G A T C C T A G G T A G C A A C C A T C G T A G G A T G G T A C C A A G C A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T A C G A A G C T T G G A A C C A A C G A A C G A A G C T A G C T A C C T A G C A T G C T T G C T A G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C T T G G A A G C A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C T T G G T T C G A T C G T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C T T C C T T G C A A C G A A G G T A C C T A C G T A C C A T G C T A C G A A G C A A G G T A C C A A G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T G G T T C G T T C G T T C G A A G G A A C C T T C G T T C C T A G G T A G C T T G C T T G G T T G G T T G C A T C C T T G C T A G G A A C G T T C C T A C C A T G C T A C G A A C C T T G C A A G G T T G C A T C C T T G G T A G C T T G G T T C G T A G C A T C G A T G G A A C G A A G C T T C C T A G G T T G C A A G C A A C C A T G C A A G G A T G C A T G G A A G G A A C C T A C C T T C G T A G G A A C G T T C G T T C C A A G C A T G C T A C C T A G C T T G G A T G G T A G C T A C C T A G C T A G G T T C G T T C C T T G C T T G G T A G C T A G G A A C C A A C C T T C C A T C G T A C C T A C C T A C C T A C C T T C C A T C G A T G C T T G G A T G G T A C C A T G C T T G C T A G G T A G G A T G C T A C G T A G C T T G G T A C C T A C C T A G C T A C G T A G G T A G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T +A G C T A G G T A C G T T C C A T G G A T G C T A G G T A C C A A C G A A G G T T G C T T G C T T G G T T C G A T G C T A G G T A G C A T C C A T G C T A C C T T G G T A G C A T G C A T G G T T G C T T G C T T C C A T C G T A C C A A G G A A G C T T G C T A C G T T G C A A C C T T C G A T G G T T G G T T C C A T C C T A G C A T C C A T G G T T C C A T G G T A G C A A G C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A C C T T C C A A G G T A G C T A G G T T G G T T G C T T G G T A G G T A G C A T C C T T C G A T G G T A G C T A C C A T C G A T G C T A G G A T G G T T G G T T G C A A G C A T C C T A C G A A C G T A G G T A C G T A C C T A C G A T G C A A G C T A G G A A G G T A C G A T G C T A G C T A C C T T C C A A G G A T C C A T C C A T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T C G T A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G C T T G C T T G C T A G C T A C G A T G G A A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G T T G C T T C C A A C G A A G C A A G G T T C C T A G C A T G G T T G C T A G G A A G G T A G C T A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T T C C T T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G G A A C C T A C C A A G G T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G G A A G C A A C C T T G C A A C G A A G G T A C C T A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T A G C A A G C T A C C T A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C C T A C C T T C G T A G C A T G C T A G C T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C A A G G A A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G T T G C A A G G A A C C T A G C T T G C T T G G A A C C A A C G T T C C T T G G A T G G T A C G T A C C T A C C T T C G T A G G A A C C A T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T A C C T A G C T A G G T T C G T A C C A A G C A T G C A A G C T A G G A A G C A A G C T T C C A T C G T T C C T A G C T A C C T A C C T A C C A T C C A T G C T T G G A T G C T A C C A T G G T A G C T A C G T A G G A T G C T A G C A T G C T A G G A A G G T A C C T A G C T A C G T A G C T A G C T A G G T T C C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRM_000021 # subpop. label: 6 (internally 6) -2 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 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G T T G G T A G C A T G G A T G C A A G G A T G C T A G C T A G C A A G C T T G C A A G G T A G C T A G G T T G G T T G G T T G G T A G G T A C C A T C C T T C C A T G G A A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T C C T A C G A A C G T A G G T A C G T A C C T A C G A T G C T A G C T A G G T A G C T A C G A T G C T A G C A T G C T T C C A A G G A T C C A T C C T T G G T T C C T T C G A T C G T A C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A G C T T G C A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C C A A G C T T C G A A G G A A C C A A C G A A C C A A G C T A C C T A G C A T G C T T G C T T G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T T G C A A G C T A G C T A G C A T G C A T C G T T G G A A C C T A G C A T G G A A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C T A G G T T C G A A G C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G G T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C T T C G A T C C T A C G T T G C T T G C T T C G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T T C G T A G G T T G C T T G G A T G G T A C C T A G G T T G C T A G G T A C G T T C G T A G C T A G C A A G G A T C C T T G C A T G G T A C C A A C G T A G G T A G C T T G G T A C G T A C C A T C C T T C G A T C G A A G C T A G C A T C C T T G C T A G G T A C C A T G C A A G G T A G C A T G G A A C G A T G C A A G C T A C G A A G G A A C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G C A A G C T A C C T A G C T A G G T T C G T A C C T A G C A T C G T A G C T A G G A A G C T A G C T T C C T T C G T T G C T A C C T A C C T A C G T T C C A T C G A T G C T T G G A T G C T A G C A T G C T A G C T A C G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C G T A G G T A G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C T A G G T A C G T T C C A T G G A T G C T A G G T A C C A A C G A A G G T T G C T T G C T T G G T T C G A T G C T A G G T A G C A T G C A T G C T A C C T A G C T A G C T T G C T T G G T T G C T T G C T A C C A T G C T A C C A T G G A A G C A T G C A A C G T T G C A A C C A A C C A T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C A T G G T A G C T A G G T A G C T T G G T A G C T T G C A A G C A A C G T T G C A A G C T A G C A A C C A T G C A A G C T A G C T A G G T T C G T T G G T T G G A A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T C C T A C G A T C G T A G G T A C G T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G G T T C G T T C C T T G C A T G G T A G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G A A C G T A G C A T C C T T G G T A G C A T C C A T C G T A C C T T G G T A G C T A G G A A G C T A G C T A C C T A G C T T G C A A G C A T C C A A C C T A C C T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G C T T G C T A C C T A G G A A G C T A C G T A G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T T G C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G A A G C A A G G A A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C C T T C G T T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C G A T C C A T C C T A G G A T G C A A G G A T C C T T C C T A C C T T C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C T T C C A T G G A T C G A A G C T T C C T A C C T T C C A A G C A A C C A T G C A A G C A T C C A T G G T A G G A A C C T A G C T T C G T A G G A A C G T A G C T T C C A A G C A T C C T A C C T A G C T T C G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T T G C T T G G T A G C T A G G A A C G A A C C T T C C A T G G A A G G T A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T T G C T A G G T A G G A T G C T A C C A T G C T A G G A A G C T A C C T A G C T A C C T A C C T T G C T T G G T T G C A A G C T T G G T T G C T A G C A A C C T A G C T A G G T A C C T A C C T A G C T A G C A A C G T A C C T BRM_000022 # subpop. label: 6 (internally 6) -2 2 2 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 1 2 1 2 1 1 1 1 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 2 2 1 2 1 2 1 1 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 2 1 2 1 1 1 1 2 2 2 2 2 1 2 1 1 2 2 2 1 2 1 1 2 2 2 2 1 2 1 1 1 1 2 2 2 2 2 1 2 1 1 1 1 1 1 1 2 2 1 2 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 2 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 1 2 1 1 2 2 1 2 1 2 2 2 1 1 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 1 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 2 1 2 1 2 1 2 1 1 2 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 1 2 1 1 2 1 2 1 1 1 2 1 1 2 2 2 1 2 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 2 1 1 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2 2 2 1 2 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 +A G C T A C G T A C C T T C C T A C C T A G C T T G G T T C G A A C C A A G G A T G C T T G C T T G C T T C C T T G C T T G G T T C C T A C C T T G C T T G C T T G G T T C C A A C G A T G C T A G G T T C C T A C C A T G C T A C C A T C G T A G C T T G G A T C G A T G C A A C C T T C C T A G C T T G C A A G C A T C G T A G C A A G G A T C G T T C C T T G G T A G G A A G C T A G C T T G G T A G C A T G C A A G C A A G G T T G C T A G C T A G C A A C G T T G C A A G G T A G C T A G G T T C C T A G C T A G G T T G G T T C C T T G C T A C G A A G G T A G G T T C C A A C G A A C G T A G G T T G C A A C C T T G C A A C G A T G C T A C G A A C G T T G G T A C G T A C C T A C G A T G C A A G C T A G G A A G C T A C G A T G C T A G C T A G C T T C C A A G G A T C C A T C G A T G G T T C G T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G C A A G C A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T C G A T C C A T G G A A C G T A G C T T G C T T C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G A A G C T A G C A A C C T T G G A T G G A A G C A T G C A A G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G T A G C A T C C T A G G A A C C T A G G T A C C T A G C A T G G T T G C T A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G G A T G C T T C C A T C C T A C G T T C G A T G G T T G C T A C C A T G G A T G G T T G C A T C C A A C C A A C C T A C C T T G C T T C G A T G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G A A G C A A G G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T T C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T T C G T A G C T T G C T T G G T T G G T T G C A T C C T T G C T A G G T A C G T T C G T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C C T T C C A T C C T T C G A A G C A A G G T A G C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T A C G A A C G T T G C T T C C T A G C A T G C T A G C A A C C T T C C T T G C A A G C T A C C T A G C T A G G T T C G T A C C T A G C A T C G T A G C A T G G A A G C A A G C T T C C A A C G T T C C T A C C T A C C T A C C T T C C A T C G A T G C T T G G A T G G T A C C A T G C T A G C T A G G T A G G A A G C T A C C A T G C T T G G T A G C T A C C T A G C T A C G T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C A A C G T A C C T T C C A T G G A T G C T A G G T A G C T A C C A A G G A T G C T T G C T A C C T T C G A T C C A T G G T A G C A T C C T T C C T A C C T T G G T A G C A T C G A T C G T T C G A T G G T A G C A T C G T A C C T A G G T A G C A T C C A A C G T T G C A A C C T T C G A T G G T A G G A T C G A T C C T A G C A T C C A T G C T A C C A T G G T T G C T A C G A T C G T T C C A A G G A A C C A A G G A A G G T A C C T A G C A A G G A A C G A T C C T A G G T A G G T A G G T T G G T A G C A T C C A A G G T A G G A A C C T T G C A A G G A A G G T T G C T A C C A T G C T A C C T A G G A A G C T T G C A A G C A T C C T A C G A A C G T T G G T A C G T A C C T A C G A T G C T A G C T A G G T A G C T A C G A T G C T A G C T A G C T T C C A A G G A T C C A T C G A T G G T T C G T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G G A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C A A G C A A G C T A G G T A C C T T G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C G A A G C T T C C T T G C A A C C A A G G T A C C T A G C T A C C A T G C T A C G A A G C A A G G T A C C A T G C A T C G A T C G A A C G A T G C T T G C T A G C A A C C T T C C T T G C A A G C T A G C A T C C A T C G A A C G T A G G T A G C A A G C T A C C A A C G A T G G T T G G T A G G A T G C T A C G A T C C T T C G T A C C T T C G T A G C T A G C T A G C T T G G A T G C A T G C T T G C T A G G A A C G T T C C T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G A A G C A A G G T A G C A T C C T T G G T A G C T A C C A T G C A T G G T T G C A T G G A A C G A A C C T A C C T T G G T A C G A A C G T T G C T T C C T A G G T A G C T A C C T A G C T T C G T T G G T T G C T A C C T A G C T A G G T T C G T A C C T T G C T T G C T A G C T A G G A A C C A A G C T A C G A T C G A A G C T A C C T A C C T A C G A T C G A T C G A T G C A T C G A T G G T A G C A T G G T A G C T A G G T A G G A A G C T A C C A T G C T T G G T A G C T A C C T A G C T A C G T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C A A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T BRM_000025 # subpop. label: 6 (internally 6) -2 2 2 1 2 1 1 2 2 1 2 2 1 1 2 1 1 2 1 1 1 2 2 2 2 2 2 1 2 2 2 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 2 2 2 1 1 2 1 2 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 1 2 1 2 2 2 1 1 1 1 1 2 1 1 1 2 2 2 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C A A C C T A C C T A G C T A C G T A G G A A G C A T C G A T G C A T G C T A C G T A G C T T C C T A C C T A G C A A C C A T C G T A C C T T G G T A G C T A G C A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G T A C C A T C C T A G G A A C C T A G G T A C C T A G C A T G C A T G C T A C G A A G G T A G C A T C C A A G C A T C G A T G C T A C C T A G G T A C G T A G C A A G G A A G G A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T C C A T C C A A G C A A C C T A C C A A G C T T C G A T G C T A C G A T C G T A G G A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C G A A G C T T C C T T G C A A C G A A G C T A C C T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C T T C G A T C C T A C G A T G G T T G C T A G G A T C C T A G G A T C C A A C 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C A T G G A T G C T A G G T A C C A A C G A A G G T T G C T T G C T T G G T T C G A T C C A T G G T A G C A T C C A T G C T A C C T T G G T A G C A T G C A T G G T T C C T T G C T T C C A T C G T A C C A A G G A A G C T T G C T A C G T T G C A A C C T T C G A T G G T T G C T T G C A T C C T A G C A T G C A T G G T T C C A T G G T A G C A A G C T A G C T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C C T T G C A A G G T A G C T A G G T T G G T T G C T T G G T A G G T A G G A T G C T T G G A A C G A A G C T A C C A T G G A A G G T A G G A T G G T T G G T T G C A A C C A T C C T A C G A T C G T A G G T A C G T A C G T A C G A A G G T A G C T A G C T A G G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G G A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C 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+A G C T T C G T A C C T A G G T A C G T A G C T A G C A A G C T A C C A A G G T T G G T T G C T T G G T T C G A T G C T A G G T A C C A T C C A A C G T A C C T A G C T A G C A T G C T T G G T A G G T T G C T A C C A T G C T A C C A T C G T A G C T T G G A A C G T T G C A A C C T T C C A T G G T A G G A T C G A T C C T A G C A T C C A T G C T T C C T T G G T A G G A A G C T A G C T T G C A A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T G C T T C G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T C C T A C G A T C G T A G G T A C G T A C G T A C G A A G G T A G C T A G C T A G G T A C G A T G C T A G C A A C C A T C C A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G G A A G C A T G G A A G G A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A G C T T G C T T G C T A G C A A C C T T G G A A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T A C G A A G C T T G G A A C C A A C G A A C G A A C C A A G C T A C C T A G C A T G C T T G C T T G G A A C G T A G C A T C C A A G C A T C G A T G C T A C C T A G G T A C G T A G C A A G G A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T C C A T C C A A G C A A C C T A C C A A G C T T C G A T G C T A C G A T C G T A G G A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G G A T C G T T G C T T C G A T G G T A C G A A G C T A C C T A G G T A C C A T G C T T C G A A G C A A G G T A C C A A G C A T C G A T C G A A C G A T G C T T G C T A G C A A C C T T C C T T G C A A G C T A G C A T C C A T C G A A C G T A G G T A G C A A G C T A C C A A C G A T G G T T G G T A G G A T G C T A C G A T C C T 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T G C T A C C T A C G T A G G T A C C A A G G A T G G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G C A T G C T A C G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T A C C T A G C A A G G A A G G A T G C T T C C A T C C T A C G T T C G A A G C A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G G T A C G A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G T T G C T A G G A T C C T A G G A A C G T A C C T T C C T T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A T G G A T G G T A G G A T G C A T G G A T C C T T C G T T C C T A C G T A G C T T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C G T A G C T A G C A A G G A A C C T T C G A T C G A 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C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T C C T A C G A A C G T A G G A T G G T A C C T A C C A T G C A A G C A A G G A T C C A A C G A T C C A T C G T T G C T T C C A A G G A T C C A T C G A T G G T T C G T T C G T T G C A T G G T T G C T T C G T A C G A A C G A A G C A A G C A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T C G A T C C A T G C A A C G T A G C T T G C T T C C T A G C A A C C A T C G T A C C T T G G T A C G A A G C A A G C T A G C T A C C T T G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T C G A A G C A A C C A T C G A A C C T A G C T A C C T A G C A T G C A T G C T T G G A A G G T A G C A T C G T T G G A T G G A T G C T A C C T A G G T A C G T A G C A A G C T A C C A T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A T G G T T G C A T C C A A C C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G T T G C T T C G A T G G T A C G A A G C A A G C T A G G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T G G A T C G A T G G T A C G A T G G T T C G T A C G A A C G A T G G T A G G T A G C A A C G A T C G A A C G A T C C T A G G A A C G T T G C T T G C A A C G T A C C A A G G T A C G T A G G A A C G A T C C T A C C T T G C T A C C T T C C A T G C A A G C A T C C A A C C A A C G T T G C A A G G A T G C T T G G A A C C A T C G A A C G A A G C T A C C T A G G T T G G T A G C A A C C A A C G A A G G T A G C A T G G A A G G T A C C T A C G T T C G T A C G A A C G T T C G T T C C T A G G T T G C A A G C A A C G T T C G T T G G T A G C T A C C T A G C T A G G T T C G T T C C T A G G A T G G T A G C T A G G A A C G A A C C T T C C A T G G A A G G T A C C T A G C T T C C T T C C A T C G T T G C T T G G A T G G T A C C A T G C T T G C T A G G T A G G A T G C T A C G A T G C T T G C A A G C A A C C T A G C T A C G T A C G T A G C T T C G T T G G A A G G T T G G T T C C T A G C A A C C T A G C T A G G T A C C T A G C T A G C T A G C A A C G T A C C T +A G C T A G G T A C G T T C C A T G G A T G C T A G G T A C C A A C G A A G G T T G C T T G C T A C G T T C G A T C G A A C C A T G C A T C C A A G C T A C C A A G C A A G C A T C G A T G G T T C G T T G C T A C C T T G C T A G C A A C C A A G C A T G G A A C G T T G C A A C C T T C G A T G G A T G G T T C C A T C C T A G C A T G C A T G C T T C C T T G G T A G C A A G C A A G G T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A C C A T C C T T C C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G G A A C C T T G G T T C C T A G G T T G G T A C G T A C C T A C G A T G C T A G C T A G G A A G G T A C G A T G C T A G C A A G C T T C C A A G G A T C C A T C C A T G G T T C G T T C C A T C G T A C G T T G C A A C G T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T G G T A C C T T G G T A C C T A G G A T G C T A G G T A C C T T G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G T A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T T C C T T C C T A C G T T C G A T G G T T G C T A C C A T G G A T G G T T G C A T C C A A C C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A 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A A C C T T C G T A C C A A C C A A C C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A C C A T G G T A C C A T G C A A C G T T C C A T G C T T C C T A G C A A C C A T C G T A C C T T G G T A C C T A G C T A G C T A G C A T C G A A G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A A G C A A C C A A C G T A G C A A G C T A C C T A G C A T G G T T G C T A G G A A G G T A G C A T C G A T G G A T C G A T C C T T C C T A G G T A C G T A G G T A G C A A G C T T G C A T C C A T C G T T C C T T G C A A G G A T G G A A C C A T G G A A G G T T G C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G A A C C T T C C T A G G A A G C A A C C A A G C T A G C T A C C T A C G A A G C T A G C T T G G T T C C A A C G A A G C A T C C T A C G T A G C A A G C T A G G T A C G A T C G T A C C A T G C T T C G A T C C T A C G A A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G A A G G T A G G T A C C A A G C T T C C T A G G A T G C A T C G T A G G A T C G T T G G A A G G A T G G A T C C T A G G A A G C T T G C T A G C A A C G T T G C T A C C A T G C A A G G T A C G T A G G A T G C T T G C A T G G T A C C A T G C A A G C A A C C A A C C T T G C T T G G A T G G T A G G T A C C T T C C T A C C T T G G A A C G A A C C T A G C T T G G T A G G T A C C A A C G T T C C T T G G T T G G T A G G A A C G A A C G T T C G T T C G T A C G A T C C T A G C A A C G T A G C A A G C A T G G T T G G A T C C A A G C A A C G T T G G T T C G A A C C T T G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A G C A T C C A T C G A A G C T T G C T T G C A T G G A T G G T T G C T A C G T A G G A A C C T A G C T T G C T T G G A A G C T A C C T T C C A A C C A T C G T T G C A T C C T T G G A A G C T T G C T T C C T A G C A A C G T A G C A T G C A A G C A T C C T A G C T A G C A A C G T A C C T +A C C T A G G T T C C T A G C T A C C T T G C T A G G A A C G T T C C A A G G A T C C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A C C A A G G A T C C A T C C A T G G A A C G A T G C T A C C A T C C T A C C A A G G A A C G A T C C T A C G T T G C A A G C T T C C T T G C T T C C T A C C A T C C T A G C A A G G A T C C T T C C A T G G A A G C T A C G A A G C T T C G T A G C T A C G A T G C A A G G T T G C A A G C T A G C A A C C T T G C A A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T C G A T G G T A G G T A C C A A C G A T G G T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T T G C A A G G T A G G A A C G T A C G A T G C T A C C T A C G T A C G A A G G T T C C A A C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C T A G G T A G C A T C C T A G G T A C C T T G G A A C C A A G G A A G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C A T C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A T C C A A C C A A G G A A C C A A G G T T C C T T G C A T C G T T C C T A G G A A G G A A C C T T G G T T G C T T C G A T C C T T G C T A G C A A C G T A G C A A G C T A G G T T G G T A C C T T C C T T G G A T G C A A G G T T G C A T C C A T C G A A C G A T G C A T C G A A G C A A G C T A G G T A G C T T C G T T C C A A C C T A C G T A C C A T C C T T G G A A G C T T C C A A G C T A C G A A C G T T C C T A G G T T G C T A C C A T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G C A A C C A A G G T A G C T A G G T A G C A A G C T A C C T T C C T A G G T A C G T T G C T A C G A T C C T A C G T A G G T T G C A A G G A T C C T T C C A A C G T T C C A T G C T T C C A T G G A A C C T A G G A A C G A A C C T A C C T A C G A T G C A T C G T A G G T A G C A T G G A T C C T T C G T T C C T T C G T A G G T T G C T T G G T T G G T T G C T T C C T T G C T A G G T A C G T A C C T A G C T A G C A T C C T T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A G G T A C C A T C C T T G G A A C G A A G C T A G C T A G G T T C C T T C C A A C C A T G C A T G G T T G C A T G G T A G G A A G G A T G G A T C C A A G G A T G G T T C C T T C C T A C C A T C G A T G G T A G G T T C G T T G G A A G C T A C G T T G G A A G C T T C C T A G C A A C C T A G G A A C C T A G C A A G G A A C C T A C G A T C G A A G C T A C G A T C C T A G C A T C G A A G G A A G C T A G C T T C C A A G G A T G G A T C C T A C G A A G G T A C C T A G C A A G C A T C G T A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G C T T G C T T G C T A C C T A G G T A C C A A G C A A C G T A G G T A G G T T G C T A G G T CGU_MN028 # subpop. label: 7 (internally 7) -2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 1 1 1 2 1 1 1 2 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G C T T G G T A G C T T G C A A G C T A G G A T G C T A C C T A G C A A G C T T G C T A G G T A G C T A G G T T G G T A G G T T C C T T G G T A C G T T G C T A C G A A C C T A G C A T C G A A C G A A G G T A G G A T G C T A G G T T G C A A C C A T C C A A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C C T T G C T A G C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T C G T A C C A A C G A A G G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T A G C T T G G A T C C T T G C T A G C A A C G T A C G A A G C T A G G T T G C A T G C A T C G T T G G T T G C A A C C A T G G A A C C A T G G A T C G A T G C A T C G A A G C A A C C T T G C A A G G A A G G T A G C T A G G A A C G A T C G T T G G A T G G T A G C A A G C T T G G T T C G A A C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A G C A A C G A A G C T T G G T A C C T T G C T T G C A T C C T A C G T A C G A A G C T A G G A T C C T A G G A T C C T A C C T A G C A T C G T A G G A A C G T A G G T A C C T A G G T A C C T A C G A T G G A T G G T A G G A T G C T T C G A A C C T T C G T T G C T A G C T A G G A T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C A A G G T T G G T T C G A A C C T A G C A A C C A A G C T A G C A A C C T T G G T A G C T A C C A T G C A T G G T T G C T T G G T A C G A T C C A A G C A T G G T A G G A T G G T T C C T T C C A A C G T T G G T A C C T A G G T T G G A T G C T T G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G A A G C T A G G A A G G T T C G T A C C A T C G T A G C T T C C T A C C T A C C A T C C A T C G A T C C A T G G T T C C T A G C A T G C T A G C T A C G T T G G T A C C T A G C A A G C A T G G T A G G A A C G A T C C T T C G T A G G T T G C T A C C T T G C A A G G T T G C T T G C T T G G A T C G A T G C T A G C T A G G T A C C T A G G T T G C A A C C A A C G T +A C C T A C G T A C C T T C C T A C C T T G G T A G G A A C G A A C C A A G G T T C C T T G C A T G G A A G G A A G C T T G G T A G C T T C C A T C C T A C C T A G G T A G C A T G C T T G G A A G G T T G G T T C C T T G C T A C C A A C G T A C C A T G G T T C G T T G G T A G C A T C G A A G C T T C C T T G C T T G C A A G C T T C C A T G C A T C C A T G G A A G G A A C C A A G C T T C G T A C G A T G C A A C G A A G G T A G C T A G C T A G G A A C G A T G C A A G G A A C G T A G G A T G G T A G C T T C C T A G G T A G G T T G C T T G C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C T T C C A A G G T A C G T A G G T A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C C T A G G A A G G A A C C T A G C A T G C T T C C T T C C A T G G T T G G A A G C A A G C A T C G A A G C A T C G A T C C A A C C A A G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A G G T A G C T T G G T A G C A A C C A A C C A A C G A A G G T A C C A A C C A A C C A T C C A A G C T A C C A T G G A A G C A T C G T T C C A A C G A T C G A T C C T T G G T A G C A A G C T A C G A A G C A A G G T A C G T T G C T T C G A A C C T T C G A A G G T T G C A A G G A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T A G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C C T T G G T T G C T T C G A A C G T T G G A T G C A T G C A T G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G C T A C C T A G C T A C C T A G G A A C C A T G C A A G G T T G C A A G G T A G G A A G C A A G C A T G G A T C G A A G G A T C C T T C C T A C G T T C G A A G C A A G G T T C G T T G C A A G C T A C G T T G C T T C G A A C C T T G G T A C G A T G G A A G C T A C C A A G G A A C G A A C C T T C G T A G C T A C C T A C C T A G C A T C G A T C G A T G C A T G G T T G C T A G C A T G C T A G C T A C G A T G G T T C C T A C G A T G C T T G G A A G C A T G C A T C C T A C C T A G G T T G C T A C G T A C C T A G G T T G C T T C C T T G C A T C G A A G C T A C C A A G C A A G C T A G G T A G G A A G G T A C C T CGU_MN029 # subpop. label: 7 (internally 7) -1 2 2 2 2 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 2 1 2 1 2 2 1 2 1 1 2 2 1 2 2 2 1 2 1 2 1 2 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 1 2 1 2 1 1 2 2 2 2 1 1 2 1 2 1 2 2 1 1 2 2 2 1 2 1 1 2 1 1 1 1 1 2 2 2 2 2 1 2 1 1 2 2 2 1 2 2 2 1 1 2 1 2 1 1 1 2 2 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 1 1 2 2 1 1 1 1 1 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 2 1 2 1 1 2 2 2 1 2 1 1 1 2 1 2 2 2 1 2 1 1 2 1 2 1 1 1 1 2 2 2 2 1 1 1 2 2 2 2 1 2 1 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 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2 2 1 1 1 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 2 2 2 2 2 1 1 2 +T G C T A G G A T G C T A G C T A C C T T C G A A G G A A C G T A C C A A G G T T C C T T G C T T G G T T G G A A C C T A G G T A G C A T C C A A C G T A G C A T G G T T G C A T G C T T G G A A C G A T C C T A G C A A C G T A G G T A G G A A C C A T C C T T C G A T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C T A G C T A G C T A C C A A C G A T G C A A G C A A G G A T G C A A C C T A G C T A G C T T G G A A G C T A G C T A G G T T G G T T G G T T G G T T G G T A C C A T G C T T G G A T G G T A G G T T C C A A C G A T G C T A C G A A G C T T G G T T G C A A G C A T G C T A C G A A C G T A C C T A G C T A C C T A C G T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G G T T C C T T C C A T C G T T C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A C G T A G C A T G G T A G G T A G G A A G C T A G C T A C C T T G G T A C C A T C G T A C G A T G G T A C C T T C G A T G G T T G C A A G G T A C G T T G G T A C C A A C G T A C G T A C C A A G C T T C G T T C C A T C C A A C G A A G C A A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A C G A T G G T A C G T T G G T A G C T T C C T T G G T T G G T A G G A A G G A A C C T A C G A T C G A T G C T T C C A A C C T A G C A A G C A T G C T T C G T T C G A T C C T T C C A T C G A T G C A T G G A A C C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A C C T A C G T A G C A A G C T A G G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G G T T G G A A C G A A C C T A C C T A C G A T G G T T C G T A G C A T G G A T G G A T C C T T C G A A G C A T G G A A G G A T G C T A G G A T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G C T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T A G G A A C C T A G C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C G A T C C T T G C A A G G T A G C T A G C A T C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C T A G C A A G C T A G C T T C C A T C G T A G C T A C G T T C C T A G C A T G C A T C G A A G C A A G G T A C C A T G C A T G C T T C C T A C C A A G G A T G C T A C C A T C C T T G G A A G C T A C C T A G C A A C C A A C C T T G C T T C C T T C C A A G C T T G C T T G C T A G C A A C C T A G C A A C C T A G G T T G C T A G C A T G C A A C C A A C G T +A G G T A C C T A C G A T G C T A C C T T G C T A G G T A G G T A C G A A G G T T C C T T G C T T G G A T G G A T G C T A G G T A G C T T G C T T G C T T G C T T G G T A G C A T G C A T G G T T G G T T G C A A G C A T C G T A C C A A G G A A G C A T G G A A C G T T G C A A C C T T C G T A C C T T G C T A C C A T C C T A G C T T C C A T G C A T C G A T C G T A G C T A C G A A G C T T C G T A G G A A G C A A C C A A G G T T G C T A G C T A G C A A G C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G C T T G C T T G C T T C C A T C C A A C C A A C G T T G G T A C G A A C C T A C G T A C C A A G C T T G G A A C G A A C G A T C C A A C G T A G C T T C C T A C G T A G C A A G G T T C G T A G G A A G C T T G C A T G G T T G C A T G G A A C C A T C G T A G C A A G G A T G G T T C G A A C C A T C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T T C C T T C G T T G G T A C C A A G C A T C G A A C C A A C G A A G G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T T C G T A G G T T C G A T C C T T G C T A G G T A C C T T G C A A G G A A C C T T G G T T G C A T C C T T C C A T G C A A C G A A G C A A C C A T G G A A G G T T C C A T C C A A G C A A C C A A G C A T G C T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C T T G C T A C G A T C C A A C C T T G G A A G G T A C C T T G C T T C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A C C T T G C A A C C A A G C T T C G A A G G A A G G T A C C A A G C A T C G A T C G A A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A G C T A G G T A G C A A G C T T C C T A C G A T G C A T C G T A G G A T C G T T G G A A G C T T C G T A G C T T C G A A G G T T G C T T G C A A C G A T C C A T G G T A G G T A G G T A C G T T C G A A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A C G T A G C T A G G T T C G T A C C A T C C T T C G T A G G A A G C T A G C A A C C T T G G T A G C A T C C A A C G T T C C T T G G A T G G T A G G A T C G A A C C T T G G T A G C A A C C A T C C T T G C A T G C A T G C T A C C T A G C T T G G A T G C A A G C T A C C T A G G T A C G T T C C T A G G T A G C A T G C A A G C T A G C A A G G A A G C T A C C A T C C T T G C T A C G T T C C A A C G T A C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G A T G C T T G C A A C G A T G C T T C G A A C C A T C C T A G C A A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A T G C A T C C T A G C A T G C A A G C T A C G T CGU_MN030 # subpop. label: 7 (internally 7) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 2 1 1 2 2 2 2 1 2 1 2 2 2 2 1 2 1 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 1 1 1 2 1 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C C A A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A G C A A C G A A C C A A C C T A C G A A G C T A G G T A C C A A C C T T G C A T C C T A C G T A C G T T G C T A G G A A C C T A G G A T C C T A C C A T G C T T C C A T G C T T C C T A G G T A C C A A G C T A C C T A G G A T G G A T C G T A G G A T C G T T G G A T C C T T C G T A C C T A G G A A G G A T G C T A G C A A C G A T C C A T G G T T G C T A G G A A C G T T C C T A C C T A C C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G A A C G T A G C A T C C A T C G A A G G T A G G A A C C T A G C T A C C T T C C A T C C A T G C A T G G T T G G A T G G T A G G A T G C T T C G A T C G A A G G T T G G T T C C T T C C A A G C A T C C T A G C T A G C T T G G A T G C A T G C A A G G T A C G A A G C T T C C A T C C A A G G T A G C A A G C T T G C A A G C A A C G A A C C T A C G T A C C T A G C A A C C T A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A A C G A A C G A T G C T T G C A A 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T A C G A A G C T A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C A T C G A T G G T T G G A T C C T T G C T A G C A A C G T A G C A A G G T A C C T T G C A T G C A T C G T T C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A T C C T A C G A T C G T A G C A A G C A T C C T A G C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A T G G T A G G T A C G A A C C A T G C T T C G A A G G A A C G T A C C A T G G A T C G A A C C T A G G A T G G A A G C T A G C A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A C C T T C C T A C C T A C G A T C C T A G G A T G C T A C G A T C G A T C G T A G C T A C G T A G C T T G C T A G C T T G G A T G C A A G G T A G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C A T G C A T G G T T G C T T C C T A C G T A G C T A G G T T C C T A C C A T C C T T C G A A G G A A G C T A C C T T G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C T A C C T T C G T A G G A T C G T T C G T T C C T A G C A T C C A T C C T A G C A T G G A T G C A A G C A A C G T T G G T T C G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C C T T G C A A C G T A C C T A C G T T C C A T C G A T G C T A G G A T G C T A G G A T G G A T C G T A C G A T G C T T G C A A C G T T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T T G C A A C C T A G C A T G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN032 # subpop. label: 7 (internally 7) -2 1 2 2 2 1 1 2 2 1 2 2 1 2 2 2 2 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 2 1 2 2 1 1 1 1 1 1 2 2 2 1 2 1 1 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 2 2 1 2 2 2 2 1 2 2 2 2 1 2 1 2 1 1 1 2 2 1 1 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 2 1 1 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 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C G A A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C A T C C A T C C T T C C T T G G T T G C A A G C T T G G T T G C T A G C A T C C T A G C T A C C A A G C A A C C T A G G T A G C T A C G T A C G T +A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G C A A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C T T G C A T G G T A G C T T C C A T G G A A C C T T G C A A G C A T C C T A C G T A G G A T G G A T C G A T C G A T G C A A G C T T C G A A G G T T G G T T G C A A C C T A G C A T G C A T G G T T C C T T G G T A G C T A C C T A G C T T G G T A G C T T G C A T G C T A G G A T G C A A C C T A G C T A G C T T G C T A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G T A C G T A G G A A G C A A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A A G C A A G G T T G G T T 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T T G C T T C C T T C G T A C C T A G G A A G C T T G C A A C G A T G C A A G C T A C C T T G G T T G G T T C C A T C C T A G C A T G C A T G G T T C C T T G G A T G C T A C G A A G C T T G G T A G C A T G G A T G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G G T T G C T A C C T T C C T A G G T A G G T T G C T A C G T A C C T A G C A T C G A A C G A T G G T A G G A T G G T T G C T T G C A A G C A T C C T A C G A A C G T A G G T A C G A A C C T A C G T A C C A A G C T A G G A A G C T T C C A T G C A A C G T A G C T A C G T A C G T A G G A A C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G C A T G G T A C G T A G C T T C C T A G G T A G C A T C G T A C G T A G C A T G G T A G C T A G G T T G C T T C C A A C C A T C C T A G C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A T G C A T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T T G C T A G C A A C G T A G C A A G G T A G C T T G C A T G C A T C C T A C G T T G G A A G G A A C G A A C C T A C G A T C G A T G C A T G C A A C C A A G C T A G C T T G C T T C G T T C C T T C C T T C G A T C C A T C C A T G G A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C G T A G C A T C G T A C G A T C C T T C G A A G C A T G G A A G G A T G C T A G G A A C G T T G C T A G G T A G G T A G G T A C G T T C G A A G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A C G A T G C A A G G T T G C A A G G A A G G A T C C T A G G A A C C T A G C A A C G T T C C T T G C A T C G T T G G A A C C T A G C A T G G A T G C A A G C T A C G T A G C T T C G A A C C T T G G T A G C T T C G T A G C A T G C A A G G A A C C T A C C A T C G T T G C A A C G T A C C T A C G A T G C A T C C A T G C A T C G A T G G T A G C A T G C T A G C T A C G A A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +T G C A A C G T A C C T T C C T A C C T A G C T A G G T A C G T T C C A A G G A A G G A T G C T A C G T T C G A A C G T T G G T A G C A T G C A T C C T A G C T T G C T A G C A T G C T T G G A T C C T T G C T A C C A T C G T A C C T A G G A A G C T T G C A A C G T T G C A A G C T A C G A A G C T T G C A T C C A T C C T A G C T T C C A T G G T T C C T A C G A A G C T A C C A T C G T T C C A A G G T A C C A A C G A A G G A T G C T A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G C A T G G A A G G T T C C A A C G A A G G T A G G T T G C T T G C T T G C A A C C A T C C T A C C A A C G T T G G T A C G A A C G A A G G T A C C A A C G T A G G A A C C T A C G A T G C T A G C A A G C T T C C A A G G A T C C A A C C T T G G T A C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A A C C A A C G T T G C T T C C T T G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G T A G C T A G C A A C C T T G G A A G C A A G G A T C C A A G G T A C G T T G C T A C G T T G C T A C G A A C C T A G C T A C C A T C G T A G G T A C C A A G G A T C G T A C C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A C C T A G C T T G C T A G C A A G G T A G C T T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C T T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C A A G C A T G C T A C G T A C G A T C G T A G C T A C G A T G C A A C G A T G G T T G C T A C G T A G C A A G C T A C G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T C C T A G G T A C G T A C C T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T T G C T T G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C G A A C G T A C C T A C G T A G C A A G G T T G G T T C C A T C C T A G C A A G C A T G C T A C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T G G A A C C A A G G T A G G T A G C T T C G T A C G T T C C T A C C A T G C T T G C T A G G A A G C T A C C A A G G T A C G T T G G T T G C A A G G T A G C A A G C A A G G A T C C A A G C T T C C A T C G T T G C A A C C T A C C T A C G A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C G A A C G A T G C T T C C A A C G T T G C T T G G A A G C A T C C A T C C A A C G A A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G C T A C G T A G G T A G G A A G G T A C C T CGU_MN034 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 2 1 2 2 2 1 2 1 1 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 2 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 1 2 1 1 2 1 1 1 1 2 1 1 1 2 1 1 2 1 1 2 2 1 1 1 2 2 2 1 1 2 2 1 1 2 1 1 2 2 2 2 2 1 1 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 1 2 1 2 2 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 2 1 2 1 1 1 1 1 1 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 2 1 1 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G G A A C G T T G G T T C G A A G C T T G C A T G C A A G C A T C G T A G C A A G G A A G C A A G C A T G G A T C G T A G C T A G C A A G C T A C C A A C C T A G C A T C G T A C C A T G G T A C G A A G G A T C C T T C C T A G C A A C C A T C G T A G C T T G G A A G C T T G G T T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T C G T A C C A A G C T T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G C T A G G A A G G T T G C A T C G T A G G A T C G T T G C T T G G A A G G T A C C T A C C A A G C A A G G T A G G T T G C T T C C A T C C A T G G A A C G A A G C A A C C A T C G A A C G A T C C A T C G A A G C A A G C A A G C A T G C A A G G T T G C A T C C T T C G A T C C A T C C A T G C A A G C T T C C T T G C T T C G A T G G T A C G T A C C A A G G T A C C A T C C A A G C T A G C T A C G T A C G A T C G A A G G A A G C A T G C A A C G T A G G T T C C T A G G T A G C A A G C T A C G A A G G A A G G T A C C A T G C A T C G A T C C T A C G A T G G A A G C T A G G T A G C A A G G A T G C T T C C T T C C T T C C A T G G T A C G A T G G T A C C A A G G T T C G T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C G T A G C T T C G T A G G T T G C T T G G T T G G T A C C A T G G T A G G A A C G T A C C T A C C T A G G T A G G A A C C T T C C T T G C T T C G T A C C A A G C T T G G T A G G T T C G T A C C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A G C A T G G T T G C A T G G T A G G A A G C A T G G A T C G T T C G T T G G T T C C T A G C A A C G T T G C A A G C T T C C T A G G A T G C A A C G T T C C A A G G T T G G T T G G A A C C T A C G T T C G T A G C T A C C A A G G A A G C T A C C A T C G T A G C T A C G A A C C T A G C A T C G A T C G A A G C A T C G T T G C T A G G A A G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C T T C C T A G C T A C C A A G C T T G C T A C C T T C C T A G C A T C C T T C C A T G G A A G C T A G C T A C C T A G C A A C G T T G C A A G G A A C C T A G C A +A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A G G T T G C T T G C A A G G T T C G A A G C T T G G T A G C A T G C T T G C T A G C A T G G T A G C A T G C A T C G T A G G A T C G T A G C A A C G T A C G T A G G A A C C A T G C T T C G A T G C A A G C T T C C A A G C A T G G T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C G T A C C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C A A C C A T G C A A G C T A G G T A C G T T C C T A G C T T C C A T G C T A C G A T G C T T G G A T G G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T G C T A C G A A C G T A C G A T G C T T C G A A C C T A G G A A C G T T G G A A C G T A C G A T G C A A C C T A G G T T C G T A C G A A G G A T C C T T G C T T C G T T C G A T C G T A C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G A A G C T A C C A T C G T A C C A T G C A A C C T T C C A T G C T T G G T A G C T T G G A A G C T A G G A T C G T A C G T T G C A A C G T A G C A T C G A T C C T A G G A T G C T T C G A T G G T A C G T T G C T T C G T T G C T A G G T A G G T T G C T T C C T T C G T T G G A T G G A A G G A T G G A T G C A A C G T A G C T A G G T T C G A T G C T A G C A A G G T T C C T A C G A A G G T A G C T T C G A T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T G C A T C G T T G G T T G C A A G C A T G C T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G G T T C C A A G C T A G C A A C C A A C C T T C C T A G G T A G C A T G C T A C G A T G C T A C C T T G C A T C G A A G C T T C C T T G G A A C G A A G C T A C C T A C G T A G C A A G C T A G G A A G G A A C G T A C C A T G C A T G C A A C C T A C G A T G G T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C C T T C G T T C G A T G C T A C G A T C C T T C G A T C C T A G G A A C G A T G C T T G C A T G G A T C C A T G G T A G G T A C G A A C G T T G G A T G C A T G C A T G C A A C C A T G G A T C C T T G C A A C C T T G C T T G C A A G G A A G C T T C C A T C G A T C C T A G G A A G C T A G C A A G C T T G C T T G G T A C C A A C G T T C C T T G G A T G G T A C C A A G G A A G G A T C C A A G G T A C C T T C C T A G C A A C G T T C C T A G C T A G C T T C G A T G C A A G C T T C C A A G C T A G C T T C C T A G G T T G C T T G C T A G C T A G C A A G C A A C C T T G C A T G G T T G C T T C G A A C C T A G C A T C C A T C G A T G G T A G G A T G C A A C G A T G G T T C C T A C G A A G G T A G G T A G C T T G C T A G G A A G G T T C C T A G C A A G C T A G C T T G C A A C G A A G C A A G C T T G C T T C C A A G C T T C G A A G C T T G C T A C C T T C C T A G C A A G C A A C C T A G C A CGU_MN035 # subpop. label: 7 (internally 7) -2 1 1 2 2 1 1 2 2 1 1 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A A G G A A C C T A G C T T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A T C C T T G G T T C G A T G G T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C A T G G T A C G T A G G T A G C A A G G T T C C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C C T A C C A T G C T T G C T T C C T T G C A T C G A A C G A T C C T A G G T T G C A T G G T T G C T A C C A T C C T T C G A A G G A A G G T A G C T A C C T T C C A T G G A A C C A T G C A A G G T A G C A T G G T A G C A A C C A T G C A T G G A A G G A T G G A T C C T T C C T A C C A T G C T A C C T A G C T T G G A T G C T T G C A A C G T A G C T A G G T T C G T T C C T A G C T A G C T A G C A T G C A A G G A A G C T T C C A T C G T T G C T A C G A A C C T A G C A T C G A T C G A A G C A T C G T T G C A A G G A T G G A T C G A A C G A A G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C A T C C T T C C A A G C A A C G T A G G T A C C T A G C A A C C T A G C T A G C A A G C T A C G T CGU_MN036 # subpop. label: 7 (internally 7) -2 1 1 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 2 1 1 1 1 2 2 1 2 1 2 1 2 2 2 1 1 2 2 1 2 1 1 2 2 1 2 2 2 1 2 1 1 2 1 1 1 1 1 2 2 2 2 1 2 2 2 2 1 2 1 2 2 1 1 2 2 2 1 2 2 1 2 1 1 1 1 2 1 1 1 2 1 1 2 1 1 2 1 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 1 2 1 1 1 1 1 2 1 2 2 1 2 1 2 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 2 1 2 1 2 1 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 2 1 2 2 1 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 2 1 2 1 1 2 2 2 2 1 1 1 2 1 1 1 2 2 1 2 1 1 2 1 2 1 1 2 1 2 1 2 1 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C C T T G C T A C C T T C G A A C C T A G C T T C C T A G G A T G C T T G C A A C C T T C C T T G C T A G G T A G C T A C C T T C C T A C C T T G G A T C C A T G C T T C G T A G G A T C G T A G C A A C G T A C C T A G G A A C C A T G C T T C G T T G C T A G C T T G C A A G C T T G G T T G C A T C C T A G C A T C C A T C C T T G C T T G G A A G C T A C C T A G C T T G G T A G C T T G C A A G C A A G G T T G C A A G C T A G C A A C G T A C C T A G C T A G C A A G G T T G G T A G C T T G G A T G C T T C G T A G C T A C G A A C G T A G G T A C C A A C G A T G G T A G G A T G G T T G C T T G C A A C C A T G C T A C G A A C G T T G G T A G C A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G T A G G A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C G A A G G T A C G A T G G A A G C T T G G T T G G T A G G T A G G A A G G T A C C A A G G T A C G A T G G T A C C T T G C T A C G T A G C A A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G G T T C C A A C C A A C C A A G C A A G G T A G C T A G G A T G C A T C G T T C G A A C G A A G G T A G C T T G G T T G G A T G G A T G C T A G G T A G G T T G C T T G C A A G C T A C C T T G C T A C C A T C C T T G G T T G G T T G G T T G C T A C G A T G G A A G G T T C C A T C C A A G G A A C C T A C C A A G C T T C G A T C G A A C C T T C G T A G G A A G C A T C G A A G C A A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T T G C T T C G T T G G T T G C T T G G T A C G T A C C A A C C A T G C T T C G A A C C T T C G A T G C T A G C A T G C T T C C A T G C A A G C A T G C A A C C T T G C T T G C T A G G A A G G T T C C T T C G T A G C A A G C A A C C T T C C A A G C T T C C A T G C A A C C A T G C A A G G T T G C A T G G T A G G A T C C T T G G T T G G T A C G A A C C A T C C T T C C T A G C A T G G A A G C T T G C A A G C A T G G A A G C T A C G A A G C T A G C T T C C T A G G T A C C A T G G T A G C T T G C A A G G A T C G A A C C T T C G T A C C T A G C A A C G T A C G A T C C A T C G A T C C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +A G C A A C G T A C C T T C C T A C G T A G G A T G G A A G C A A C C A A G G A T G C T T G C T T G G A A C G A A C C T A G G T A G C T A C C T T C C A A C C T T G G T A G C A A G C A T C G T A G C T T G G T T C C T T G C T A C C A A C G A A C C A T C G T T C G T T G C A A G C T T C G T A G G T T G C T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C T A G C T T C C A A C C A A G C A A G C T A G G T A G C T A C C T A C C A A C G T T C C T T G C A A C G A A G G T T C C T A G C T T C C A T G G T A C G T A G C T T G G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T C C T A C G A A C G T A G G A A G C T T C G T A C G T A C G A A C G T A G G A A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A A C C T T G G T A C G T T C G A T C G T A C G T T G C A A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G C T T C C A T G C A A C G T T C C A T C C T T G G T A G C T T G G A A G G T A G G A A C G A A G C T A G G A A C G T A G G A T G G T A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T T G G A A G G A T G C A A G C T T C C T A G G A A G C A A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T A G C T A G G T A C G T T G C T T G C A T G C A T C C T A C G T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G G T A G G T A C C A A G C A A G C T A C G T T C G A A G C T A C G T T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T A C G T A G G A T G G T A C G T A G G A T C G T T C G A A C C T T C G T T G C T A C G T A G C T T G C T T G G A A G C A T G C A T G G T A G G A T G G A A C G A A C C T A G G T A G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G A A G G T T G C A T C C T T C G T A G G A A G C T A G C A A G C T T C C T T G C A T C G T T G C A A G G T T G G A T G G T A G G A T G C T T G G A T G C A T C G A T G G T A G G A T G C A A C G T T C C T A G C T T G G T T C G T T G G A T G C T T C C T A G C T A G G T T C G T A C C T A G C T A G G T A G C T A G G A A G C A A C C T A C C T T C G T T G C T A C G T A C G T A C G A T C C A T C G A A G C T A G G A T G C T A C G T T G G T T C C T A C G A T C C A A G G A A G C T T G C T T C C A T C C T T C C T T C C A A G G T A G G T T G C A A C G A A C C T A G C T T G C T T C C A A G G A A C G T A G C T T G C A A G C A T C G T T G C A A G C A A C C T A G C A CGU_MN039 # subpop. label: 7 (internally 7) -1 1 2 2 2 2 1 1 1 2 1 2 1 1 2 2 2 1 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 1 2 2 1 2 2 1 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 2 1 1 1 1 2 2 1 2 2 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 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T A G G A T G C T T C C T T G C A A C C A T C C T A C G A A C G T A G G T A G G A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T G C T A C C T A C C T T C C A A G G A A G C A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G C A A G G A T G G T A G C A A G C T A G C T A G G T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T A G G T A G C A T C C A A G G T A C G A T G G A A G C T A G G A A G C T A G C A A C C T A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A A G C T T G G T A C C A A G G A T C C T A G C T A G G T A C G T A G G A A G G A A G C T T G C T T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C C T A G C A A G C A T C C T A G C A A C C A A G G T T C G A T C C T A C G T T C G A A G G T A C C T T C C T A G C T T C C A A C C T A G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A C G T A C C A A C G T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A T G G A T G G T A C C T A G G T A C G T A G G A T G G A T C G T A G G A T C G T T G G A A C C T T C C T A C C T A G C T A G G A T G C T A C C T A C G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C A T G C A A C C A T G G A T C C T T G C A A C C T T G C T T G C A A C G A A C G T A C C A T C C T T C G A A C G A A G G T A G C T A G C T T G C T A G C T A C C A T G C A T G G T T G C A A G G T A G C A A G G A T G C T T C G T A G G A A C G T A C C T T C C A A G C A T C C T A C C T A G G T T C C T T G G A A G C T A C C T A G C T A G G T T C G T T C C T T G G T T G C T A G C T A G C A A G C A A C C T A C C A T C G T A C C T A C C A A C C T A C G A T G C A T C C 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T T C G T A C C A A G C T A G G A A G G A A G C T A C C A T G C A T C G A T C C T A C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T T C G T A C G A T G G A T G G T A G G A T G C T A G G A T C C T T C G T T G C T T C G T A G G T T G C T T G G T T G G T A C C T A G G T A G G A A G C T A C G T T G C T A G C T A G C A A C C T T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C G A T G G A T G C A A G C T T C G A A G C T T C G T A G C A A C G A T G C T A G G T T G C A T G C T T G C A A C C T T G G T T C G T T C G T A C G T T C C T T G C A A C G T T G G A A C C T A G C A T C C T T G G T A G C T A C G T T G C T T C G A A C C T A G G T T G C T A G G T A G C T A G C A A G G A T C G A T C G T T G C A A G C T A C C T A C G T A C G A T C C A T C C A T G C T T G G A T C G A A G G A T G G A T C C T A C G A T G C T A C C A A C G A T G C T T C C A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G G A A G G T T G G T T C C A A G C T A C C T A G C T A G G A A C G T T C C T A G C A T G C A A G C T A C G T CGU_MN040 # subpop. label: 7 (internally 7) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 1 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 1 1 2 2 1 1 1 2 1 2 1 2 1 2 1 2 2 1 1 1 2 2 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 1 1 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 2 1 1 1 2 2 2 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 1 1 1 2 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 1 1 2 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 2 2 1 1 2 1 2 2 2 2 2 2 2 1 2 1 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 2 2 2 2 1 2 1 1 1 2 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 1 2 1 2 2 1 1 1 2 1 2 2 2 1 1 1 1 2 2 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 1 2 1 1 2 1 1 1 2 2 1 1 2 1 1 1 1 1 1 1 2 1 1 1 2 1 2 2 2 2 1 1 2 2 1 2 1 2 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C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G C T T G G T A G G A A C C A T G C A A G C T A G C A A G G A A G G A A C C T A G C T T C G T A G G A A C G T T G C T T C C A A G C A T G C T A G C A A G C A T C C T T G G T A G C T T C C T A G C T A G G T T C G T A G C T A G G T T C G T A G C T A G G A A G G A A C C T A C C T T C G T T G C T A C C A A C G T A C G T T C C A T C G A A G G T A G C T T C C A A G C A T G C T T C C T T C G T A G C A T G C T A G C A T G C T T G G A A G C A A C C T A G C T A C C A A C C T T G C T T C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C A T G C A A G C A T C C T A G C A T G C A A C C A A C G T +A G C T T G G A T G C T T C C T A C C T A G C T A G G A A G C T A C C A A G G T T G C T T G C T A G G T T C G A T G C T T G G T A C C T A C C T A G C T A G C A T G G T A C C A T C G T A G G T T C C T T G G T T C C A T C C A T C G T A G G A A C C A T G C T T C G A T G C T A G G T T C C T A C C T T 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G G A T G G T A G G A T C G A A C C T T G G T A G C A A C C T T C G T T C C T A C G T T G G T A C C T A G C T T G G A T G C T T G C T A C C T A G C T A G G T T C G T A C C T T C G A T G C A A G C T T G C A A G G A A G C T A C C T T C G T A G C T A C C T A C C T A G C A T C G A T C G A A G C T T G G A T G C T A C C A T G C T A G C T A G G T A G G A T C C T A G C A T C G T T G G T A C C A T C C T T G C T A G G A A C C T T G C T T C C T T C C T A G G T T G G T T G C T A G C T A C G A T G C T A G G A T G C A T G C T T G G T A G G A A G C T A C G T CGU_MN041 # subpop. label: 7 (internally 7) -1 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 2 1 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 2 1 2 1 1 2 1 1 2 1 2 2 1 2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 2 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 1 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 1 1 2 2 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A T C G T T G C T T G C A T C C T A G G A A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A T C C T T C G T T G C T A C G T A G G T T G C A T G G T T G G T T G C T T C C T T G C T A G G A A C G T T C C T A C C T T G C A T G G A A C C T T G G A T C G A A C G A T C C T A G G T A C C T A C G T A C G T A C C A T C C A T C G A A C G A A G G A A C G A A G C A A C C T T G G A A C C A T C G T T C C T T G C T T G G A A G G A T C C T A C C T T G G T A G C T A C G T T C C T T C C A A G C A T C C T A G C T A G C A T C C T T G G A A G C T T C C T A G C T A G G T T C G T T C C T T G C T T G C T A G C T A G C A A G C A T C G A T C G T T G C T T C C T A C C T A C G A A C C T T C C A T C C A T G C A T C G A T C G A A G G A T G G A T C C A A C G A T G C T T G C T A C G A T G C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C T A G C T T G C T T C C T T G C A T C G T A G G T A C C T A G C T T C G A A G C T A C C A A G G T A C C T CGU_MN042 # 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C T T C C A A G G T A C C T A G G A A G G T A G G A A G C A A G C A A C C T A G G T A C C A A G C T T C C A T C C A A G C T T G C T T C G T T G C A A G G T T G G T T G G T T C C T T C G T T G C T A C C A A G G A T G C A A G C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T T G G A A C G T A G C A T C G A T G G T T G G A T C C T A G C T A G G T A G C T T G C A A G C T A C C T T G C A T G C A T C G T T C C A T G G T A G C A A G G A A C C T A C G A A G C T A G C T T C C A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C C T T C C A T C C A T G G A T G C T A G C A A G G T T C G A T G G T A C G T T C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T T C C A T G C A A C G A A G C T T C C T A C G A A C C A T G C T T C G A A C C T A G C T A C G A A G C T T G C A A C C T A C G T A C G T T G C T A C G A A C C T A G G A T G C T T G C T T C C T T C C A T G G T T C C T A G G T A C G A A C C T T C C T A C G A T G C T T C G T A G G A T C G T A C G A T C G A T G G A T C C T A G G A A G G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T T C G A T C C T T C G T T C C A A G G A A C G T A G C A A C C T T G C A A C C A T G C A A G C A A G G A A G G A A G G A A C C T A G C T T C G T A G G A A G G T T G C T T G C A T C G T T G G A A C C A T G C A T G G A T G C A A G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C G A A G C A T C G T T G C T A G G A T G G A A C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C A A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN044 # subpop. label: 7 (internally 7) -2 2 1 1 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 1 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T G C A A G C T A G G A T G C A A C C T A G C A A G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C G A A G G T T C C A T G G A A G G T T G G A T G C T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T T G C T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T A C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C C T A C G T T C G A A G C T A C C T T G C T A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A A G C T T G G T T G G A T G C A T G G T T G C T A G G T A C G T T C C T A G C T A G C T T C G A A C C A A G C A T C C T A C C A A C C T T G C T T G C A A G G A T G C T A C G A T C C T T C G A T G G A A G C T A G C T A G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G T A C G A T G C A A C G T T G G T A G G A T C G T T C C T T G C A A C G T T G G A A G C T A G C T T G G A T G C T T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C G A A G C A T C G T T G C T A G G A T G G A A C C T A C G A T G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +T G C T A C G T A C G T T G C T A C C T A G C T A G G T A G G T A C C A A G G A T G C T T G C T A C G A A C G A T G C T A G G T A G C A T C C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T A G C A T C G T A G C T A G G A T G C A T G C A A C C T T G C A A C C T T C G T A G G T T C G T T C C A T C C A A G C A A C C A T G C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G C A A G G T A G C A T C G A A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A T G C A A C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A C G T A C C A A C G T A G G A A C G A A C G A T C C T A C G T A G G T A C G A A C G A T C C A A G G T T C G T A C G T T C G A T C G T A C G T T G C T A C G T A C C T T C G T A G C A A G C A A C G T A G G T A G C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T C C A A G G T A G C A T C C A A G G T A C G A T G G A A C C T T G G A A C G T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T A C C A A C G A A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G C T T G G A T G C T A C G T A G G T T G G T T G G A A G C A T G C A T C C A A C C T T C C T T C C T T G G T T C C A T C G A A G C T A C G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A C C T A C G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T C G A A C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T T C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T G C T A C C T A G C T T G G T T G G A A G C T A C C T A G C T A G G T T C G T T G C T T G C T A G G A A G C A T G C A A G G A A G C T A C C A T C G T T C C T A G C A A C C T A G C A T C G A A G G A T C C T A G G A T G C A A C C A T G C T T C C T T C G T A G G T A C C A A G C A T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T T C C T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A G C A A C G T A C G T A G C T A G G T A G C A A C G T CGU_MN045 # subpop. label: 7 (internally 7) -2 2 1 2 2 2 1 1 1 2 2 2 2 2 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 1 1 2 1 1 2 2 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 1 1 1 2 2 2 1 1 2 1 2 1 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 1 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 1 2 1 2 1 1 2 2 2 1 1 2 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 1 1 2 2 1 2 2 2 1 1 2 1 2 2 2 2 2 2 1 1 1 2 2 1 1 2 2 2 1 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 2 2 2 1 2 1 2 2 1 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 2 2 2 1 1 2 1 2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 1 2 2 1 1 2 2 1 2 1 1 2 1 2 1 2 1 1 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 2 1 2 2 1 1 1 1 2 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1 2 2 2 1 2 2 2 1 2 2 2 2 2 2 1 1 2 +A G G T A G G A T G C T A G G A T G C T A G C T A G C T A C G T T C C T A G G A T C C T T G C A T G G A T C C T A C G T T G G T A G C T A C C T T G G T A G C T T G G T A G C T T C C A T C G T A G C T T C G T A G C A A G C T A C C A A G C A A C C A T G C T T C C T T G C A A G C T T C C T T G G T T G C T A C G A T C C T A G C A A G G A T C C A T C G A A G G T A G G A A C C T A G C T T C G T A C G T A G G A A C C A A G G A T G C T A G C T A C C A A G G T T C C T T G C T T G C T A G G T T G G T A G C T T C C A A G G T A G G A T G C T T C C A A G G A A G G T T C C A A C C A T G G T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G T A C G A T G C T T C G A A G C T A G G A A C C T A G G A T C G A A C G T T C C A A C C A A G C T T C G A A G C A T G G A A C G T A C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G G A A G C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G G T A C C A T G G T A C G A A G G A T C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G C T T G C T A G C T A C C T T G G A A G C A A G G T T C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G G T T C G T T G C A A C C A A C G A A C C A A G G T T C C A A C C A T G G T T G C T A G G A A C G T A G C A T C G T T G C A T G G A T C C T A G C T A G C T T G C T A G G A A G G A A G C T T G C A T C C A T C C T T C C A T G C A A C C A A G C A A C C T A C G T A G C T T G C A T C G A A G C A A G C T A G C A A C C T T C C T A G C A A C C T A C G T A C C A T C C T T G G A T G C T T C C A A C G T A C G A A C C A A C G A A C G A A G G T A C C A A C C A A G C A T G C T A G C T A C G T T C G T A G G A A C C A T G G T A C G A T G G T A C C T A G G T A G C A T G C T T C G T A G C A A G G T A G G T T G C T T C G A A C C T A C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G A T G G T T G C A A C C T T C C T T G G A T C C T T C G T A G G A T G C A A G G A T C C T T C C T A C C T A G C T T G G A T G C T A C C T A G G T A C C A T G G T T G C T A G G T A C G T T C C T A G C T A G C A A G G T A C C T T G C A T C G A A C G A T C C T A G C T T G C A T G G A T G C T A C C A T C G A T C G A A G G A A G C T A G C A A G C T A C C T T G G A A C G A T G C A T G C A T G G A T G G A A G G A A G G A T G C A T G G T A C G A A C G T T G C T T C G T A C G T A C G T T G C A A G C T T G C A A G C T T G C T T C C T T G C T T C G T T G G A T C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C G T T C C A A C C T A C C A A C G A T C C A T C C A T C C T A G G A T G C A A G C A T G G A T C C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C C T T C C T A G G A T G C T T C C A A G C T A C G T A G C T A C C T A G C T A C G T A G G T A G G A A G G T A C C T +A G G T A G G T A C G T T G C T A G C T T C G A A G G T A C G T A C G A A G G T T G C T T G C T T G G T T G G A A G C T T G G T A G C T A C C T T G C A A C C T T G C T A G C A T G C T T G G T T C C T T G G T T C C T T G C T A C C A A G G A A C C A T G C T T C G A T G C A A G C A T C G T A G G T T C G A T C G A T C C A A G C T T C C A T G C A T G C A A G C A T G C T A C G A A G C T T C G T A G C T T G C A A G C A A G G A T G C T A G C T A G C A A G C T T C G A A G C A A C G T A G C T T C G T A C C T T C C A T G C T A C G T T G C T T G G A A C G A A G G T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T G C A A C C A A G G A T C C T A G C T T C C T A G G T A C C A A C G T T G G T A G G T A C G A T C C A A C C T T G C T T C G T T C G A A G G T T C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G C T A G C A A C C A A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G A A G C T A G G A A G G A A C G A A G G T T C C A T G G A T C G T A C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G G T T C C T T C C T T C G T A C C A A G G A T G G A T G G A A C C A A G G A A G C A A C G A T G C T T G C T T G C A T C C T A C G T A G G A A G C T T G G A T G C T T C G A T G C T A C G T A G G T A C G T T G C A A G C A A C C T T G C A T G C A T C C T T G G T T C G A A C G A A G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A C C T T G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C T A C G T A C C A T G C A T C G A T C C T A C G A T G G A A G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T T G C A A G C T A C C A A C C A T C G A T C C T A G G A T G C A A G G A T C C T T C G T A G C T A C G T A G G T A G C T A G C T T G G A T G C A T G G T T G C T A G G A A C G T T C C T A G C T A G C A T G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T G C T T G G A A C C A T G C A A G C A T G C A T G G T A C G A T C C T A C C T T C G T A G G A A C C T T C G T T C C T A C G T T G G T A C C T A G C T T C C T T G G A A G C T A C C T A G C T A G G T T C G T T G C T T G C T A G G A A G C A T G C A A G G A A C C T A C G A T C C T T G C A T G C T A C C T A C G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G T A C G T A C C A A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G C A A G C A T C G T A G G T A G G T A G C T A C G T CGU_MN046 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 1 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 1 1 1 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 1 1 2 1 2 1 1 1 2 1 2 1 2 2 2 2 1 1 1 1 2 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T G C A A G C T T C C A T G G A A C G A A G C A T C C T A C G T A G C A A C C T A G G T A C G A A G C T A C C T T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T C G A A C C A T G G T A C G T A G G T A C C A A C C T T C C T A C G A T G C T T C G T A G G A T G C T T G G A T C C T A C G T A G C T A G G A A G G T T G C T T G C T T G G T T G C T A G G T A G C T A G G T A C G T T G C A T G C T A G C A A G G T T C C A T G C A T C C T A C C A A C C T A C C T T G C A T C G T A C G T T C G A T C G T T C G T A G C A A G C T A C C T T G C A A C C T T G C A A C C A T C C A A G G T T G G T T G G T A G G A A G C A T G G A T C G T A G G A T G G A T C C T T C G T A G G T A G C T A G C A A G G T T G G T T G C A A G C A A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G A A G C T A C G T T C C A A G C A T C G A T C G A A G C A T C G A T C G T A G G A T G G T T C G A A C G A A G G T T G C T A C G A T G C T T G G A 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C T A G C A A G G T A G C T T G G A A C G A T G C T A G C A A C G T A G C T T C G A T C C A T C C A A G C A A G G A A C C T T C C T T G C A A G C T A C C A T C G A T C G T A G C A A G C A T C C A A G G T T G C T A C C T A C C A A G C T A C C T T G C T T G C T A C G T T G G T A G G T T G G T A G G T A C C A T G C T A C G A A C G A A G G T T C C A A C G T T G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C A A C G T A C G A A G G A A C G A A G G T A G G T A C G T A G G A T C C A A C G A T C C T T C G T A G C T T G G T T C G A A G G A A C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C G T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A A C C A A C G A A C C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A A G C A T C G A T G G T T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G G T T G C A T G C A T C G T T G G A T G G T A G G A A G C T T C C A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T A G C A T G C A T G G A A G G T A C C T T G C T A C G A A C G T A C C A A G C T A G G T A C C A A G C T T G C A T G C A A G C T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G T T C G A A G G T A C G A T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T T G G A T G C A A G C T T C C T A C C A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C C T A C G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C A T G C A A C C A T G C A T C C T T G G T T G G T A G G A A G C A A C G T T C G A A G C A A C G A T C C T T C C A A G C T T G C T A C C T A G C A T C C T T G C A T G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A A C C T A C C T T C G T A G C T A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A C G T A G G T T G C A A C C A T G C T T G G A A G C T A C C T T C C T T C G A A G G T T C C T T C C T T G C A A G C T T G G T T G C T T G C A T C C T A G C T A C C T A G G T A C C T A G G T A G G A A C C T A G C A +A G C T A G G T T C G T A G C T A C C T T G C T A G G T A C C A A C C A A G G T T G C T T G C A T G G A A C G A A C C T A G G T A C C A A C C T T G C T A G C T T G C T T G C A T C G A T C G T T C G T T G C T A G C A T C G T A C C A A C G T A G C A T G C T A C C A T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A C C A A C G T T G C T A G C T A G G T A G G T T G G T A G G T T G G T T G C T A C C A T G C T A C G A A C G T A G C A T C G A T G G A A G G T T G G A T G C A T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A C C A A G C T A G G T A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A T C G T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G C T T G G A T G G A T C C T A G C A A G C A A G G T A C C T A G C A T G C A T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G C T A C C T T G C T T C C T T C C T T C C T T G C A A G C A T G G A A C C A T G G A A G G A A G C A T C C A A C C A A G C T T C C T T G C T T C C A T G C A T C G A T C G T A G C A A G C T T G C T A G C A A C C A A C G T A C C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G A A G G A A C G T A C G A T G C T T C G A A G C T A C G A T G G A A C G A A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A C C T A C C A A G C T A C C T A C C A T G G T T G C T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A T G C A A G C T A G C T A G C T A C C T T G C A A C C A T G C A T G G T T G G A T G G A A G G A A G G A A G C T T G G A T C G A A C G T A C C T T C C T A G C A T G C T A C C T A G C T T C G A T C C A T G C T A C C T A G C T A G G T T C C T A G G T A C G T T C G T A G C T A G G A A G C T A G C T A C C A T C G A A G C T T C C T A C C A A C G A T C C A T C G A T G G A T C G T T G C A A G G A T C G A T C G A A C G A A G G T T C C A A C C T T C C T T G G A A G C T A C C T A G C A A C C A A C C T T G C T A C C T T G C A A G C T T G C T T G C T A G C A A C G T A G G T A G G A A C C T A C C T A G G T A G G T A G C A A C G T CGU_MN050 # subpop. label: 7 (internally 7) -2 2 1 1 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 1 1 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 2 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 1 2 2 2 1 2 2 1 2 1 2 2 2 2 1 2 1 2 1 1 2 1 2 1 2 1 2 2 2 2 2 2 1 2 1 1 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 1 1 1 1 1 2 2 2 2 1 2 1 2 1 2 2 2 2 2 2 1 2 2 2 1 1 1 1 1 2 2 1 1 2 1 1 2 2 1 1 1 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 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T C G A A G C T T G C A T G C A T G C T T C C T T C G A A G G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A C G T A C C T T G G T A C C T T G G T T G C A A G C T A C C T T G G T A G C A A G G T T C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G C T T C G A A G C T T C G T A C C A A C C T A G G A A G C T A G C T A G C T A G G A A G G T T G C T A C G A A G G T A G C A T C G T T G C A T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G G T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A C C A A G C T T C G A A G C T T C C T T C C A T C G A T G C A T G G A A C C A A C C T T G C T A C G A T C G T T C C T A C C T T G G T A C C A T G C T T C C A T G C A A C C T T G C A A G G A A G C T A C C T T G G A A C G A T G G T A C C A A C G T A G C A A G C T A C G A A G C T A G G T A C C A A C C T T G C A T C C T T C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C G A T G C T T G G T A G C T A C C T T G G A T G G T T G C A T G G T A G G A T G G T A C G T T G G A T G C T A G C A T G C T T C C T T G C T T C G T A C C A A C C T T G C T A G C A A G G T A C G T T C C A T C C T T C G A A G G A A G G A A C C T T G C T T C C T T G G A A C C A T C G T T C C T T G G A T G G A A G G A A C G A A C C T T C G T A G G A A C G T T C G T T C C T A C C A T C G A A C C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C C T T G G T T G C T T C G T A G C T A G C A A C G A A C G A A C G A T C G T T G G T A G G A A C C T A C G T T C C A T C C A T G C T A G G A T G C T A C G A A G G A T C G A A C G A T G C T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C A A G C T T G C T T C C T T G G T A G C T T G G T T C C A A G G A A C G T A G C T T C C A A G C A A C C T A G C T A G C A A C G T A C C T +A C C T A C G T A C C T T G C T A G G A T G C T A G G T T G G T A C C A A G G A T C C T T G C T T G G A T G G A T G C T A G G T A C C A T G C T T G C T T G C A T G G T A G C A T C C A T G G A A G G T T G C T A C C A T C C T A C G T A G G A A C C A T G C T T C G T T G C A A C C T T C G T A C C T T G C T T C C A T C C A A G C A A G G A A C C T T C C A T G G A A G C T A C C T A G C T T G G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C C T T G G A A G C T A C C T A G G T T G G T A G C T T G G A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A T G C T A C C T T G C A A C C A T C C A A G G A A C G A A C G T T G G A A C G A A G G T A C C A A C G T A G G A T C C A A C G A T G C A A C C T A C C T T C C A A G G A T C C A A C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C G T A G G A A C C T A G C T A G G A A G G A A G C A A G C T T G G A A G C A T G G T A C G T T G C A T G C A A G G T A G C A T G C A A G G T A G C T A G G A A C C T T G G A A G G T T C G A A G G A A G G T A C C A A G G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G C T T C C A A G C T T G G A T G C A T C C T A C G A A C C A A G G T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T C G T A G G T T C G A T C C T T C C T A G G T A C G T A C G A T G G T A C C T T G G T A G C T T C C T T G G T T G G T A G G A A G G A A C C T A C G A T C G A T G C T T C C A A C C A A G C A A G C A T G C T T C G T T C G A A C G A T C G T A G C A A G C T T G C T A G C A A C C A A C C T A C G A T C C A A C C T T G G T T G C T A C C A T G G T T G C T T G C A A C C T T G C A T C G A T G C T T C C A T G G T A C G A T G C T T C G T A G C A A C C A A C G T A C C T T C C T A G G T A C C A T G C A T C G A T C C T A C G T A C G T T G C T A C G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C T A G C A A G G A A C C T T C G A T C C T A C C A A C C T T G C T A G C A A G G T T C G T T G G A T C G T A C C T T G G A A G C T A C C T T C G T T C C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A A G G A A C C T T G G A T C G A A G C T T C C T T C C T A G C A T G C T A G C T A G C T T G G T T C C A A G C T A C G T A G G T T C G A A C C T A G G T T G C A T G C A A G C T T G C A A G G A A G C T T C C A T C C A T G C A A C C T A C C A A G C A T C G A T C G A A G C A T C G A T C G T A G G A T G G T T C C T A C G A A G C T T G C T A C C A T G C T A G G A A G C T A C C T T C C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T A C C A A G C A A G C T A G C T A G G T A G C A A C G T CGU_MN051 # subpop. label: 7 (internally 7) -1 2 2 1 2 1 1 2 2 1 2 2 2 2 1 1 1 2 1 2 2 2 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C T A C C T A G G A A G C T A G C T T G C T T C C A T C C T T G G T T G C A A C C A T G G T T C C A T G C A T G C T A G C A T C G A A G C T A C C T T G C T T G C T T C C A T C C A A C G A A C G A T G C A T G C A T G G A A G G T A C C A A C G A A G C A A C C A A C C A A G C T A G G T A G C T T G C T T G C A T G C A A G C T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A G G A A C G T A C G T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T C C T A G G T A C G T A G G A T G C A A G C T T C C T A C G A T G C T T C G T A G G A T C G T T G G T A G C T T C G T A C C T A G G A A C G A T G C T T G G T A C G T T G C A T G G T A G C T A G G T A C G T A C C T A C C A T G C T A C G T T C C A T G C A T C C T A C C A A C C T T G C T T G C T T G G T T G G T A C C A T C C A T C G A A G C A A G C T A G C A A G C A A C C T T G C T A C C A A C G T T C C T T G G A T G G T A C C A A G C A A G C T T C G A A C G T A C G A T C C T A C C T A C G T A G C T T G C T A G C T T C G T T C C A T G C T A C C T A G C T A G G T T C C T T G G T A C G T T C G T A G C T A G G A A G C T A G C T A C C A T G C A A G C A A G G T A C G T A C C A T G C A T C G A A G C A T C G T T G C A A G G A T C G A T C G A A C G A A G G T T C C A A C C T T G C T T G G A A G C T A C C T T C C T T C G A A G G T T C C T A C C T T G C A A G C T T G C T T C C T A G C A T C C T A G C T A C C A A G C T A C C T A G G T A G G T A G C A A C G T +A G C T A C G T A C C T T C C T A C C T T C G A A G G T A C G T A C C A A G G T T C C T T C C A T G G A A C G A T C C T A G G T A C C A T G C T T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T C G T A C C A A C G T A G C A T G C A A C G T T G C A A C C T T C G T A G C T T C G A T C C A T C C A A G C A A G G A A C C T T C C T T G C A A G C T A C C A A G C T A C G T A C G A A G G A A C G A T G G A A G C T A C C T A C C A A C G T A C C T A G C A A G C T A G G T T C C T A G C T A G G T T G C T A C C A T G C T A C G A A C G T A G C A T C G A T G G A T G G T T G G A T G C T T G G A T G C A A C G T T G G T A C G A A C G A A C G A T G C T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C C T A C C T T G G T T C G A A G G A A G G T T G G T T C C T T C C A T C G T A C G T T G C T A C G A A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C A T C C T T C C T A G C A A C C A T G G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T G G A T G G A A C C A A C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G G A A G C T A G G T T G C A T G C A T C G T A G G T T G G T A G G A T G G A A C C A T C C A A G G A A G C A T G C A A C C T A C C T A C C A A G G T T C G A A G C T A C G A A C G T A G C A A G C T T G C A T G G T T C C T T G C T A C G A A C G T A G G T T G G T A G G T A C C A A C C A A G C A T G C T A C G T A C G A T C G T A G C T T C G A T G C A A C G A T G G T T G C T A C G T A G C A A G C T A C G A A G G A A C G T A C C A T G C T T C G A A G C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T G G T T C C T A G G A T G C T T C G A A C C T T C G T A G C T A C G T A G G T T G G T A C G T A G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C G A A C C T T G C T A G C A A G C T A G C T A G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G T A G G A T G C T T G G T T C G A A G C A A C G T A C C T T C C A A G C A T G C T A C C T A G C T T C G A T C C T T G C T T C C T T G C T A G G T T G G A A C C A A C G T T C G A A G C T A G G A A G G T A C G A T C C T T C G T T G C T T C C T A C G T A C G A T C C A T C C A T G G A T C G T T G C A A C G A A G G A T C G A A C G A A G G A T G C T A G C T T G C T T G C A A C C A A C G A T C C A A C C A A G C T T G G A T G G T T G C A A G G T T G G T T G C T T G C T T C C T T G C T A C C T A G G T A C C T A G G T A G G A A C C T A G C A CGU_MN052 # subpop. label: 7 (internally 7) -2 1 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 1 2 1 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 1 1 2 2 2 1 2 1 1 1 1 2 2 1 2 1 2 2 2 2 1 2 1 1 2 1 2 2 2 2 2 1 1 2 2 2 2 1 2 1 1 1 1 1 2 1 2 2 1 2 2 2 2 1 1 1 1 1 2 1 2 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 1 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 1 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 1 2 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 2 2 1 1 1 1 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 2 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T G G T A C C T T G G T A C G A A C G T A G C T A G C T A G C T A C C T A G C T T C G T A C C A A G C T A C G T T G C A A G G T T G C T A C C A T C C A T C G A A C G A A G C T A G C T T G C T A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A T G C A T G G T A G G A A C G A T C C T T G C A T G G T A C C T A C C T A G C T T G G T T C C A A C G T T C C A A G G T T C G T T C C T T G G T T G C T A G G A A G C A T G C A A G G A A G C T A C C A T C G T T G C A A C C A A C G T A C G T T C C A T C C A T G C T T G G A T G C T A G G A A G G A A C G T A C G A T G C T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C G T T G C A T G C T T G C T T G C T A G C A A C G T A G C A T G C A A G C A T C C T A G C T A G C A A G C T A C G T CGU_MN053 # subpop. label: 7 (internally 7) -2 2 1 2 2 1 1 2 2 1 1 1 1 2 2 2 2 1 1 2 2 1 2 2 1 1 1 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 1 2 2 2 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C T T G C A A G C A T G C A A C C T A G G T A G G T A G G A A C G A A G G T A C C A A G C A T G G A A G G T A C G A T C C T T C C T T C C T T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T T G C A T C C T A G C T A G C A T C G A A G G T A G C A T G G A A G C T T G G T T G C T A G C T A C C T T G C T T G C A T C G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G C T A G C A A G C T A C C T A G C A A G G T A C C T A C G A A G G T A G C T T G G T T G G A T G G A T G C T T G C T A G G T A C G T A G G A A G G A A G G T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A G C A A C C T A C C A A G G T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G G T T C C T T G C T T C G A T G G T A C C T T C C A A G G T A C C A T G C T A C G A T G C T A C C T T G C A T C G A A G C T T C C T T G G A A C G A A G C T A C C T A C C A A G C A A G C T A G G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A C C T T G C A T C C A T G G A A G C T T G G T T G C A A G C T A C C T A C C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T T G C T A C G T A G G A T G C T A C G A T G G T A C C T A G G T T G C T T G G T A C G T T C G T T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C T T C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G G T T G G T A G G A A C C A A C G T T C C A T G G A T G G A A G G A A G C T T G G A T G G T A G C A A C G T T C C T T G C A A C G T T G G A A C C T A G C A T C C T T G G T A G C T T C C T A G C T A G G T T C G T A G C T T G C T A C G A A G C A T G C A A G G A A G G A T C C T T C G T T G C A A C G T A C C A A G C A T C C A A C G A T C C T T G G T T G C A A G G A A G G A T C G A A C G A T G C T T G C T A G C T T G C T T G G A A G C T T C C T A G C T A C C A T C C T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A T G C A T G C T A G C A T G C A A C C A A C G T +A C C A A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C G A A G G T T G C T T C C T A C G A A G G A A C C A A G G T A G C A T C G A T C C A A C C T T G G T A G C A T G C A T G G A T C C T T G G T A C C A T C C T A C G T A G G T A C C A T G C A A C G A T G C A A G C T T C C T T G G T T G G T T C G A T C C T A G C A A G G A T C C T T C C A A C G A A G C T A G C T A G C T T G G T A C C T T G C A A G C A A C G T T G C A A G C T A G C A A C G T A C C A A G C A A C G T A G G T T C C T A C C T A G G A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C G A A G G T A G G T A C G A A C G T T G C T A C C T T G G T T C C T A C G T A C G T A G C T A C C T A G C A T G G A A C G T A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T A G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T A G G A T G C A T C C A A C G A A G C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A C C A T G C T T G C A T C C T T G G T T G C A A C C A T G C T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T C C A T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G G T A C C T A C G T T G C A A C C T A C G T T C G A A G C T A C C A T G G A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G G T A C C T T C G A T G C A A C G T A G G T A G C A T G G A T C C T T C G T A G C T A C G A A C G A T G C T T G G T T G G T T G C A A G G T T G C T T G G T A C G T A C C T A C C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C T A G G A T G C T T C C A T C C T T C G T A G G A A G C T A G C A A G C T A C C T T G G A A C G A T G C A T G G T T G G T T G C T T G C T A C C T A C C T T G G A T G G A A C G T T G C T T C C A A G C A T C C T A G C T A G C A T G G A T G C A A G C A A C G T T G G T T C G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A G G A A C C T A C G T A C C T A G C A A C C T A C C A T C G A T C G A A G C A T C G A T C G T A G G A T G G T T C G A A C G A A G G T A C C T A G C A A G C A T G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C C A A C C A A C C T A G G T A G G T A G C A A C G T CGU_MN056 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 1 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 1 2 2 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 2 2 2 1 1 2 1 1 1 1 1 2 2 2 1 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 2 1 2 1 1 2 1 2 1 1 1 2 1 2 2 2 2 2 2 1 1 1 2 2 1 1 2 1 2 1 1 2 1 2 2 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 2 2 1 1 1 2 1 2 2 2 1 1 2 2 2 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 1 2 2 1 1 1 2 1 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 1 2 1 1 2 2 2 2 1 2 2 2 1 1 1 1 1 2 2 1 1 1 1 2 1 2 1 1 1 1 2 2 1 1 2 1 1 1 2 2 2 2 1 1 2 2 2 1 2 1 1 2 2 2 2 1 2 2 2 1 1 2 2 1 2 1 1 2 2 1 1 2 1 1 2 1 1 2 2 1 2 2 2 2 2 2 1 2 1 2 1 2 1 2 2 1 2 2 2 1 2 1 2 2 1 2 2 2 2 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 1 1 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 2 2 1 1 2 2 1 1 1 1 2 2 2 2 2 2 1 2 1 2 2 1 1 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 2 1 1 2 1 2 2 2 2 2 1 1 1 2 2 1 2 2 2 1 1 1 2 2 1 1 2 2 2 1 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T G C A A C C A T G G T T C G T T G C T A G C A T C C T T C C A A C G T T G C A T G C A A C C T T G C A A C C T T C G T T G C T T C C T A C C A T C C T T G G T T C C A T G C A T C C A T G G T A G C T A C G A T G C T A C C A A C G T A G C A A G C A T C G A A G G A T C C A A C G A T G C A T G G A T G C T A C G T A G G T T C C T A G G T A G G A A G G T T C C T T C C A T G G A A G G T A G C T A C C A A C C A A G G T A G G T T G C A A G C T T G C A A C C A T G C A A C C A A C G T A C G T A G C T A C G A A G G T A C C A A G C A A G G T A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T T G C T T C C T T G G T A G C A T C C A A G G T A C G A T G G A A G G T A G G A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A C G T A C C A A G C T T C G T T C C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T T G C T A G G T A C C T A G C A A G C T A G C T T G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G G A T G C T T C C A T C G A A G C A A C C T A G C T T G C T T C G T A G C A T C G T T C G T A C C A A G C A T G G A A G G T A C C T T G C T A C G A T C C T T C C T A C C A A G G T A G C A T G C T T G C T T C C A A C C T A G C A T C G A T G C A T C C T T G G A A C G A A G C T A C C T A C G T A G C A A C C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G G A A G G T A G G T A G C A A G C A A G G T A G G A T C G T T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T A G G A T G C T A C C T T G G T A C C T A G G T T G C T T G G T A C G T T G G A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T T G C T T G C T A G G T A G C T A G C A T C C T T C G A T G C A A C C T A G C T A G G T T C C T T C C A A C C A T G C A T G G T T G C A T G G T A C G A T G C A A C C T T C G T A G G A A C G T T C C T T C C T A C G T A G C T A G C A T G C T T G G A T G C A T C G T T C C A A G G T T C G A A C C T A G G T T C G T A G C A A G C T T G G A A G G A A C C T A C C T T C G T T G C T T C C A A C C T A C G A T C C A T C C A T G C T A G G T T C C A A G G A T G C T T C C T A G G T A G G A T G C T A C C T T G C T T G G A A G C A T C C A T G G A A C C A A G C T T G C A A C G T T G C T T G G T T C C T T C C T T G G A A C G T A C G T T G C T A G G A A G C T A G G T A G G T A G C A A C G T +A G G T A C G T A C C T A G G A T G G A T G C T T G G T A C G A A C C A A G G T T G C T T G C T T G G A A G G A A G C T A G G T A G C A T G C A A G C T A C C T T G G T A G C A T G C A T G G T T C C T T G C T A C C T T G C T A C C A A G G A A C C A T C G A A C G T T G C T A G C T T C C T T G C T T C C T T C C A T C C T 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T G G A T C C T A C G T A G G T A C G T A C G A A G G T A G C T A G C A T C C A T C C T A C G T T C G T A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C A T G G T T C G A T C G T T C C T A C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T G C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G A T G C T T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A G G T T G G T A C C A A G G T A C G T A C G A T G G T T C G T A G G A T C G T T C G A A C C T T C C T A G C T A G G A A G G A A G C T T G C A A G G T A C C A T G G T A C C T T G G T A C G A A C G T A G C T A G C A T G G T T C C A T G C A T C G A A C G A T C C T A G G T A G C T A C C T A G G T A C C A T C C T T G G A A C G A A G C T T C C A A G C T T G C T T G C A A G C A T G C A T G G T T G G A T G G T A G G A A G G A T G G T T C G A A G G A A G G A T C C T T C C A A G C T T C C A A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T T G G T A C G T T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C C T A C C A A G C A T G C A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C G A A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C T A C C T A G C T T G C T A G G A A C C T A G C T A C C A A C C T A G C A CGU_MN057 # subpop. label: 7 (internally 7) -2 1 2 1 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 1 1 1 2 2 1 2 1 2 1 1 1 2 2 2 1 2 1 2 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 1 2 1 1 1 1 1 1 2 2 2 2 1 2 1 1 2 1 2 2 2 2 1 1 2 2 2 2 1 1 1 1 1 1 1 2 2 1 2 2 1 2 1 2 2 2 1 1 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 2 1 2 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C T T C C A T G G T T C G T A G G T T G C A A C C A A G G T A G C A T G G A T C G T A G G A T C G A A C G A T C C T T C G T A C C T A G G A A G G A T G G T A G C T T G G T T G C T A G G T T G C T T G G T A C G T T G G A T G C T A G C T A C G T T C C T T G C A T G G T T G C T A C C T A C C T A G C T A C G A T G C T A G C A T C G A T C G A A G G A A G G A A C C T A G C T T G G T A G G A A C C A T G C A A G G T T G G T T G G T A G G A T G C T T G G A A C C A A G G T A G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G C A A C G T T G G T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G C A A G C T T C C T T C G T T G C T A G C A A C C T A C G T T C C A T C G A T G C T A G G A T G C A A G C A T G G A T C C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C C T T G G T A G C T T G C T T C C A A G C T A C C T A G C T T C C T A G C T A C G T A G G T A G G A A G G T A C C T CGU_MN058 # subpop. label: 7 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A G G T T G C A A G C T A G C A A G C T T G C T A G C T A G C T A G G T T G G T A G G T A G G A A G C T A C C T A G C T A C G A A C G A A G G T T C C A A C C A T G G T A G G A T G C T T C C T T G C A A C C A T G C A A C C A A G G T A C G A T G C T T C G A A G G T A G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G T T C C A T C G T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A C G T A G C A T G C A A C G T A G G A A C G T A G G T T C G A A G G T T G G A T C G T A C G A T G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T T G G T A G G A A G G A T G G A T G C A A C C T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T T C G T A G G T A C G T A G C T T G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C A A G C A T C G A T G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T A G G A T C C T A C C T A C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G G T A C G A T G G T A G G T A C G T A G C A A C C T A C G T T C C A A G G T A C C T T G C T T G C A T C C T A C G T A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G A A G C T A G G T A C C T A G C A A G C T A C C T A C C A T C G T A G G T A G C A A C G A T C C T T C G A A G C A T C G A A G C T T G C T A G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G T A C C A A C G A A G G T T G C A A G G A A G G A T C G A T G G A A C C A A G G T A G G T A C C T T C G T A C G T T C C T A C C T A G C T T C G T T G G A A G C T A C G A A G G T T C G T T G G T T G C A A G G T A G C A A G C A T G C A A G G A A C C T A C C A T C G T T G C A A C C T A C C T A C G A T C C A T C C A T G C A T C G A T G G T A G C A T G C T A G C T A C G A T G C T T C C A A C G T T G C T T G G A A G C A T C C T T G C T A C G T A C C A T G C T A C C T T G C A A G C T T G C T T C C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T A G C T A G C T T G C T A G C T A G C T A C G A A G G T T G C T T C C T T G G T T C G A T G C A A G G T A G C A T C C A A G C T A C C T A G C T A G C T T G C A T G G A T C C T T G C A A G C A T C G T A G C T A G G A T G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G G A T G G A A G C T T C G T A G C T T G C A A G C T A G C T T G C T A C C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T A C C A T G G T A G G T A G G A T G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A A G G T T G C T T G C A A G C A T G C A A C C A A C G T A C G A A G C T T G G T A G G T A G C A A G C T A G G T A C G A A C G T T C C A A C C T A C C T T C C A A G G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C T T C C T A C G A A G G T A G G T T C C T A G C A T C G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T T G C T A G C T A C C T A G G A A G G A A C C T T G C T T C C T T C C T A C G A T G G T T G C A T G C T A C C A T G G A T C G A T C C A T C C A A G C A A G C T T G C A T G G T T C C A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A C G T T C G A T G G T A C G T A C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G G T A C C A A C G T A G C A A G C T A G G T A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A G C A T G G A T C G T A G G A T C G A T G G A T C C T T C C A T G C A A G G A A G G A T G C T A C C A A C G T A C C T A C C A T G C T A G G A A C G T T G G A T G C T A G C A A G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T G G T T C G A T G G T T C G A T G G A A G C T A G C T A G C T T C C T T G G A A C G A T G C A A G G T T G G T T G C T T G C A T G C T A G G A T C G T A G C A A C C A T C C T T C C T A C G T T C C A A G C T A G G T T G C T A G C T T C G T T C G A A G G A A G C T T C C T A G G T T G C A T C G T A G C A T G C A T G G A A G C T T C C A T C G T T G C T A C G A A C C T A C C A T C G A T C G A A G C A T C G A T G C A A G C A T G G A T C G A A C G A T G C T T C C A A C G T T G C T T G C A A C C A T C C T T G C T A C G A A G C T A G C T T C C T T C C A A G G T T G C T T C C A A G G A T C G A T G C T A G C T A G C T A C G T A G G T A G G A A G G T A C C T CGU_MN061 # subpop. label: 7 (internally 7) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 1 2 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 1 2 1 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 2 1 2 1 1 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 2 2 2 1 1 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 1 2 2 1 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 2 2 2 2 2 1 1 1 2 1 1 2 2 2 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 1 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 2 2 1 2 2 2 2 2 1 1 1 2 2 2 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1 1 2 1 2 1 1 2 1 1 2 1 2 1 2 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 1 1 2 1 1 2 1 2 1 1 2 1 2 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 1 2 1 2 1 1 2 1 1 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 2 2 1 2 2 1 1 1 1 2 1 2 1 2 2 2 1 1 2 1 2 2 1 1 1 1 2 1 2 2 1 2 2 1 2 1 2 1 2 1 2 1 1 2 2 2 2 1 1 1 2 2 2 1 2 2 1 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 1 2 1 1 1 2 1 2 2 2 2 2 2 2 1 2 2 2 2 2 1 1 2 1 2 1 2 2 2 1 2 1 1 2 2 1 2 2 1 2 2 1 1 1 2 1 2 2 1 1 2 1 1 1 1 2 2 1 2 2 2 2 2 2 2 2 1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 1 2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 1 2 1 2 2 2 2 1 1 2 1 1 2 1 2 1 1 2 1 1 2 2 2 2 1 1 2 1 1 1 2 1 2 2 2 1 2 2 2 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 1 1 1 1 2 1 1 2 2 1 2 1 1 2 2 2 1 1 2 1 2 2 2 1 2 2 2 2 1 2 1 1 2 1 1 1 1 1 2 1 2 2 1 2 2 2 1 2 1 2 2 1 2 2 1 2 2 1 1 2 2 2 1 2 1 1 2 1 2 2 2 1 2 2 2 2 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 2 1 1 1 1 2 1 2 2 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 2 1 1 2 2 1 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2 1 2 1 1 2 2 1 2 2 +T G C T A C G T A C G T T G C T A C C T T G C T A G G T T G G T T C C T A C G A T C C T T G C T T G C A T C G T A C C T A G G T A G C A T G C T T G C T A G C A T G G T A G C A T G C T T G G A T C C T T G C T A C C T T G C T A C C A A G G A A G C T T G C A A C G T T G C A A C C T T C G A T G G T T G G A T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C A A G C T T C G T A G C T T G C A A G C T A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T T G G T T G G T A G G T A G G A A G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A G C T T C G T A G G T T G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G C T T C C T T G G A T C C T A G G T A G C A T G G A A G G T A C G T T G C A A C C T A G G T A G C T T C C A T G C A T C C T A G C A T C C T T C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G C T A C C T A G C A T G C A T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T T C C T T C C T A C G A T G G T T G G A T G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A C C T T G G T T C C A T C G A A C G T A C G A T C C A A G C A T G G A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A A G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A C C T A C G T T C C A A G C T A C C A T G G A T C G A A G C T T C G A A C G T T G C T A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G G T T C G A T G G T T C G A T G G A A G G A A C G T A G C A A C C T T G G A A C C A A G C A A G G T T C G T T G G T A G G A T G C T T G G A T C G A A G G T A C G T A C C T T G C A A C G A T C C T A C C T A G C T T C C T T G G T A G C T A C G A A G G A A G C T T C C T A G G T T G C A T C G T A G C T A G G A A G C A A G C T T C C A T C G T T C C T A C C T A C C T T C C T A C C A T C C A T G C T T G G A T G C T A G C A T G G T A G C T A G G T A G G A T G C T A C C T T G C T T C C A A G G T A C C T A G C T A C G T A C C A T G C T A C G T T G C A A G G T T G C T T C C T A G C A A C G T A G C A A G C A A C G T T C C T A G C A T G C A A C C A A C G T +A C C T A G G T T C G T A G C T A C C T T G C A A G G A A G G T A C G A A G G T T G C T T G C T T G G T T C G A T C G T T G G T A G C T A C C T T G G T A C C T T G G T A G C T T C C A T C G T T G G T T G C T A C C A T G C T A C C T A C G T A G G A T C C T T C C A T G C A A C C T T C G A A G G T T G C A T C C A T C C T A G C A T C C A A C C T T C C T T C G A A G C T A C G A A G C T T C G T T G C T T G C A A G C A A G C T T G C T A C C T A G C A A C G T A C C A A G C A A C G T A G G T T G C T A G C T A G G A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C G A A G G T A G G T A C G A A C C T T G C A A C C A A G C T A C C A T C G T A C G A T G C T T C G A A C G T A G C A A C G T T C G A A G G T A C G T T G C A T C G T T G G A A G G A A G G T A G C A A G G T T G G T T C G A A G C T A G C A T G G T A G C T T C G A A C C A T G G A A C C A A G C A T G G T A G C A A G C T A G C T A G C T A C G T A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A C G T A C C T T G G T A C C T A G C A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T C G T T G 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C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C G T T C C A T C C A T C G A T G G A A G C T A G C T A G C T T C C T T G G T A C C A A C G A A G G T T G C A T G C T T G C A T G G A T G G A T G G T A G C A A C C A T C C T T C C T A C G T T G C A A G C T A G G T T C G T T G C T T C G T T C C T A G C T T C G A A C C T T G G T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C G T A G C T A C G A A C C T A C G A T C G A T C G A A G C A T C G A T G C A A G C A T G G A T C G A A C G A T G C T T C C A A C G A T G C T T G G A A C C A T C C T T G C T A C G A A G C A T G C T A C C T T G C A A G C T T G C T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN062 # subpop. label: 7 (internally 7) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 2 1 1 1 2 1 2 2 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 2 1 1 1 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 1 2 2 1 1 2 2 1 2 2 1 1 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 2 2 1 1 1 2 1 2 2 2 2 1 2 1 1 2 1 1 2 2 2 2 1 2 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T G G T T G G A T C C A T C G A T C C T T C G T A G C A A G C T A C G A A G G A A G C T A C G A A G C T T G C A A C C T T C G A A G G T T G G A A G G A T C C T T C C A A C G T T C C A T G C T T C C A T G G T A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C A T G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C C T T G G A A G G A A C C T A G C T T C G T A G G T A C C A A C C T T G G T T G G A T G G A A G G A T G G A A C G T T G G A A G G T A C C A T C C T T C C T A C G T T C C A A G C T A G G T T C G T T G C A T G C A A G G T A C C A A G C T T C C T A G C T A G G A T G C A A G C A T G C A A G G A T C C T T C C A T C G A A C C A A C C T A C C T A C G A T C G A T C G A T G C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A G C T T C C T T G G A A C C A T G C T 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C A A G C A A G C A A G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G C T T G G T A C C T T G G T A G G T A G G T A G C T A C G A A C G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A C C A T G C A A C C A A G G T A C G A A G C T T C G T A G G T A C C A A C G T A G G A A C G T A C G A T G C T A C C A A C C A T C G A A G G T A G C A A G G T T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C G A T G G T A C G T A G C T T C C T A G G T A G C T T G G A A G G T A C G A T G G A A G C T T G G T T G C T A G C A A G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G G T A G G A T C C A A C C A A C G A A C C A A G G T A G C T T G C A T C G T T C C T A C C T A G G A A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G C T T G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A T C G A A C C T T C G T A G G A A G C A T C G A A G C A A G C A A G G T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G A T C G A A G G T A C C T A C G A A C C A T G C T A C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T T C G T A G G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A A C G T A C C A T C C A T G C T T C G A A C C T T C C T A G G T A G C T A G C T A C C A A G C A T G G T T G C A A C C A A C G T T G C A A G G A A G G T A G C A T C C T T C G T A G C A A C C T A G C A A G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A C C T T G G T A C G A A C G T A C C T T C C T A G C A T G C T A G C T A G C A T G G A T G C A T G C T A C C T A G C T A G G T T C G T T C C T A G C T T G G T A G C T A G G A A G C A A G C T T C C A T C G T T G C A A C C A A C G T A C G A T C C A T C G A T C C T T G G T T C G A T G G T T G C T A G C T A G G T A G G A T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A T C G T T C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T CGU_MN067 # subpop. label: 7 (internally 7) -2 1 1 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 2 2 2 1 2 2 1 2 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 1 2 2 1 2 2 1 1 2 1 1 1 1 2 1 1 1 2 1 1 2 1 1 2 1 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 1 2 2 1 1 1 2 2 2 2 1 1 1 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 2 2 1 1 2 1 2 1 2 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A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C A A C C T T G G T A G C A A G C A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T A G G A T C C A A C C A A C G A A C C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A C C T T G G T T G C A T G G A T C C T A G C T A G C T T G C T T G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A C C A T G G T A C C A T G C A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C G T T G C A A C C T A C C T A G C A A G C T T G G A A G G T A C C T T G C T A C G A A C G T T C C T A C C T T G G T A C C A A G C T T C C A T G C A A C C T T G C A T C G A T G C T T G C T T G C A A C G A A G C T A G G T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C A T C G A T C C T A C G T A C G T T G C T A G G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A C C T T C G T A G C A T C G A T C G T T C G T T G C A A G G A A C C T T C C T A C C T T C G A A C G T T G C T A G C A A C G T A C C A T G G T A G C T T G G T A C G T T C G A A G C T A C C A T G G T T C C A T G C A T G G T T G C A A C C T A C G T T G C A T C G T T C C T T C C T T C C A T C G T T G G A A C C T A G C T A G C A A C C T T G G A T C G T T G C A A G G T T G G T T C G T A G G A T G C T T G G A T C G A T C G A A C C A T C G T T C C T A C G T T G G A A G C T A G G T T G G A T G C T T G C T A C C T A G C T A G G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A G C T T C C T T C G T T G C T A C C A A C C T A C C T T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C G A A C G A T G C T T C C A A C C T T G C T A G G A A G C A A C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +A C G T A G G T A C G T T G C T A G C T T C G A A G G T T G G T A C C A A G G A T C C T T G C T A C G T T C G A T C C T A C C A T G C T A C C T T G C T A C C T T G G T A G C T T G C T T G G T T C C T T G C A A G C A T G G T A C C A A C G A T G G A T G G A T C C T T G G A A C C A A C C A T G G T T G C T T G C A T C C T A G C T T C C A T G C A T C C T T G G T T G G A T G G A T C G T T C G T A G C T T G C A A G C A A G G T A G C T A G C T A C C A A G G T T C C T T G C T T G C T A G G T T G G T A C C T T G G T A G G T A C C A T G C T T C C A A G G T A G G T A C C A A C C A A G G T A G G T T G C T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C A T G G A A C C A A G C A T G G T A G C A A G C T A G C T A G C T A C G T A G C A A G C T T G G A T C C A T G C A A C G T T G C T T C C T T G G T A G C T T G G A A G G T A G C A T G G A A G C T A G G A A G G T T G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C A T G G A T G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T A G C T T G G A T C C T A G C T A G C A A C G T A G G A A G G T A G C T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A A C G T A G C A A G C T T G C A A G C A A G C T T G C T A C G A A C C T T C C T A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A G C T A G G T T G C T T G G A A C G A T G G A T C C T T G C A A G C A A C C T A C G A A G C T A G G T A C C A A C C T T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A C C T A G C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T C C T A G G A A C C A T G C A A G C A T G C A T G G T A G G A A G G A T C G T T G G A T C G A T C G T T C C T T G C A A C G T T G C T A G C A A G G T T C G T T C C A A G C T A G G A A G C T A G C T T G G T A G G T A C C A T G G A A C C T A G G A A G C A A C C T T C C A T C G A A G C T A C G A A C C T A C G A T G C A T C C A A G C A T C G T T G C A A C G A A G G A T C G A A C G A A G G A T G C T A G C T T G C T T G C A A C C A A C G A T C C A A C C A A G C T T G G A T G G T T G C A A G G T T G C T T C C T A G C T T C C T T G C T A C C A A G C T A C C T A G G T A G G T A G C A A C G T CGU_MN068 # subpop. label: 7 (internally 7) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 1 2 1 2 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C T A C C A T C G T T C G T A G C A A C G A A G C A A G G T A C C T A G C T A G C A A C G T T G C A A G C T A G G T A G G T T C C T A G C T T C C A T G G T A C G A T G C T T C C A A G G T A G G T T C C A A C G A A G C T A G G A T G G T T G C T T G C A A C C A T C C T A C G A A C G T T G G T A C G T A C C T A C G A T G C A A C G T A G G A A C G T A C G A T G C T A C G T T C C T T C G A A G G T T C C A T C G T T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T C G T A C C A T G C A A C C T T C C A T G C T T G G A T C C T T G G T A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C C T T G G T A C C A A G C A T G G A T G G A T C C T A G G A A G G T A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G G T T C G A T C C T A G C T A G G T A C C T T G G A A G G T A C C T A G C A T G C A T C G T T G G A A G G T A G G A A G C T A G C A T C G A A G C T T G C A T C C A A C C A A C C T T C C T T G G T T C C A T C C T A G G T T C G A T C G A T C C A A G C A T C C A A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C C T A C G T T C G A A G C T A C C A T G C A T C G A T C C T T C G A T G C T T G C A T C G A A C C A A G G A A C G T A G C T A G C A T C C A T G G T A C G T T C C T A G C A A C C T A C C T A C C T A C G A T C C T A G G A T G C T T G G A A C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G G T T C C T T G G A A C C A A G C A A G G T T G G A T G G T T G C A A G G A A G C T T C G T A G G A A C C A T C G T T C C T A C G T A G C T A G C A A G C A T G C T T G C T T G C A A C G A A G G T T C G T T G G A A G C T A G G A T G C A A G C T T G G A A G G A A C C T T C C T T C G T T G C T T C C A A C G T A C G A T C G A T C G A A G G T A G G T T C C A A G C A T G C T T C C T T C G T A G C A A C C T A G C A T G C T T G G A A G C A A C C T T G C T A C C A A C C T T G C T T C C T T C C A A G G T T C C T T C C A A G C A A C G T A G C A T G C A A G C A T G C T T G G T A G G A A G C T A C G T +A G C T A G G T A C G T T G C T A C C T T G C T A G C A A G C T A C G A A G G T T G C T T G C T A G G T T G G A T G G T T G G T T G C T A C C T A G G A A C C T T G C T A G C A A C G A A G G A T C C T T G C T T C C A T C C A T C G T A C G A A C C A T G C A A C G T T G C A A C C T T C G T T G C T T G C T T G C A T C G T A G C A A G G A T C C A T C G A T C G A A G C T T G C T T C C T T G G T A G C T T G C A A G C A A G G A T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A A G G A A G C T T G C A A C C A T C C A A G G A A C G A T C G T A C G T A C G T A G G A T G C A A G C T A G G A A C G T A C G A T G C T A C C A A C C A T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T T G C A T C C T A G C A T C C T T G G T A C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G G A T G C A A G G T A C C T T G C A T G G T T G G A A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C A T G G A T G C A A C C A A G C T A G G T T C G A T G C T A G G A T C G T T C C T A C C A A C G T A G G A A C C T A G G A T G G A T G C T T G C T A G G T A C G T T G C T T G C A A C C T A G C A A C C T A C C T T C C A T G C A A G C A A G C A A C C T A C G A A C G A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C G A T G C A T G G A A C C A A C C T T G C T A C G A A C C T A C C T T G G T A G G T A G G T A G G T T G C T T G C T A C G T A C G A T C G T A G C T T C C T T G C A A C G A A G C T A C C T A C G T A G C A T G C T A C C T T C C T A G G A A C C A T G C A T C G A T C C T T C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A C C T T C C T T G G A T G G T T G G T A G G T A G C A T G G A T C C T T C G T A G C T A C G T A G C T T G C T A G C T T G G A T G C A A G G T T G C T A G G T A C G A T C C T A C C T A G C T A C C T T C C T T G C A T C G A A C G A T C C T T G G T T G C A T G G T T G C T A C G A T C G T T C G T A G G A A G C T T C C A A G C T T G C A A G C A A C C A T G C A T G G T T G C A T G G T A G G A A C C T A G C T T C G T A G G A A C C T T C C T T G C A A C G T T G G A A C C A A G C A T C C T T G G T A G C T A C C T A G C T A G G T T C G T T C C T T G C T T G G T A G C A T G C A A G G A A C 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C T T G C T A C G A A C G A A C G A T G C A T C C T A C C T A C C A A C G T T G G A A C G A A C G T T C C A A C G T A C G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G C A A C G T T C C A T C C T A C C T A G C A A C C A T C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A T C C A A C G A A C G A A C C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A C C T T G G A T G C A T G G A T C C T A C C T A G G T A C G T A G C T T G C A T G C T T G C T A C G A T C C T T C C T T G G T T G G T T G C A A G C A T C G A A G C T A G C A T C G A A G C A A G C A A G C A T G C A A G G T T G C A T C C T T C C A T C C A T C C A T G G A A G C T T G C T A G C T A G G A T G G T A C C T T C C T A G G T A C G T T C C T A C C A T G C T A C C T T G C A T C G A T G C T T C G A T G C A A C G T A G G T T G C T A G C A A C C A A G C T T G G A A G C T A G G T A C C A T G C T T G C A A G C T T C G T A G G T T C G T A C G A A C C A A G G A T G C T T C C A A G C A T C C A T G G A A G G T T G G A A C G T A G G T T C G T A C C T A C C A T C G T A G G A A C G A T G C A T C C T T C G T A C C A T G G A A C C T T G C T T G C A A C G T A C C T A G G T A G G A T G G T A C G A A C C T A G C T A G C T A G C A T C C T A G C T T C G T A C C A T C C T A C G T T G C A A G G A A C C T A C C A T C C A T G G A A G G A A G C T A C C T A G C T T G G T A G G A A C C A T G C A A G G T T G C A A G C T T G C A A G G A A G C T T C G A T C G T A C C A T C C T A G C A A C G T T G C T A C C T A G G T T C G T T G C A A G C T T C C T T G G T A C G T T C C T A G C T T G C T A G G A A G C T T G G A A G G A A C C T A C C T T C G T A G C T A C C T A C G T A G C A T G G A T C G A A G C T T G C A T G C T A C C A T G C T A G C T A G G T A G G A T G C T A C C A T G C T T G G A T G C A T C C T T C C A A C G A A G C T A G C A A C G A A G C A A G C T T G C T T C C A A G C T A C G A T G G T A C C A A G C A A C C A T G C T A G C A A G G T A C C T +A C C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T A C C A A G G T T C C T T G C A A C G A A C G T A G C T A C C T A G C A T C C A T G G T A G C A T G G T T G C A A G C A T G G A A G G A T C G T A C G A T C C A T C C T A C G T A G C A T C G T A C C A T G C T T G C T T C C A A G G A T G C A A C C A T C C T A G C T T C C A A C C T T C G A T G C A T G C T A C C A T G G T T C C A A G C T T G C A A G C A A C G T T G C A A G C T A G C A A C C T T G C T A G G T A G G T A G G T T G G T A G G T T G G A A G G T A G G A T G C T T C C A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C T A G G T A G G T A C C T A G G T A C G A T G C A T C G T A G C A T C C T A C G T A C G A A G G T T C G T T C G A A G C T T G C A T G G T T C C A T G G T A C C A T G G T A G C A A G G A T C G A T C G A A C C T A C G T T C G T T G C A A C G T A G G A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A A C C T A G G T A C G T T G C A A C G T A G G A A C G A A C C A T G G A T C C A T G G T A G G T A C C T A G C A A G C T T G C A T C G T T G C T A C G T T G G A T C C T T G G T A C G T A C G T A C C A A G C T A G C A T G G T T G C A A C G T A G G T T C G A T G G T A G C A T C G T T C C T A C G T A G G A A C C T A C G T A C C T T G G A T C G T T G G T T G G T T C C T T G G T T G G T A G C T T G C A T C C A T C C T T C G T T G C A A G C A T G G T A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G G T A G C T T C C A T C C A A C G A A C C A A G C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G T T C C T A G G A A G C A T C C A A C C A T C C T A C C A T G C T T C G A A G C T A G C A T G G T A C G A T G G T A G G T A C C A A C C A T G C T A C G T T C C T A G G T A G C A T G G A T G C A T C C A T C G T A G G T T C G T A C G A A C C T A G G A T G C T T C C T T C C T T C C A T G G T T C C T A G G T A C C A A G C T A C C T T C C A T G C A T G G T A G G T A G C A A C G A T C G A T C C T T G C T T C G T A G G T T G C T T G G T T G G A T G C A T G G T A C C T A G G T A C G A A C G T A G C T A C C T A G C T A C C A A G C A T G G T A C C A A G C A A C G T T G C A T G G T T G C T A C C A T C C A T G G A A G G A A G C T A G C T A G C T A C C T T G C A T C G T T G C A A G G T T G G A T G C T T G G A T G C A T G G A T C G A A C G A A C G T T G C T T C C T A G C A T C G A T G C T A G G T T G G A T G C A T G C T T C G A A C C A A G C T T C C T A G C A A C G T T C G T A G C A T G C A A G G A A C G A A C C T T C C T A C C A A C C A A C G T A G C T T G C A T C G A T C C T A G C T T C G A A G C A T G G T T C C T A C G A A G G T A C C T T G C A T G C T T G G T A C C A T C C T A G C T A C C A A C C T T G C T T C C T T C C T A G G T T G G T T G C T A G C T A C G A T G C T A G G A T G C A T C C T A G C A T G C A A C C A A C G T CGU_MN073 # subpop. label: 7 (internally 7) -2 2 2 2 2 1 1 2 1 2 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 2 2 2 1 2 1 2 2 1 2 1 2 1 2 1 2 2 2 1 2 1 2 1 1 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 1 1 1 1 1 2 2 2 2 1 1 2 2 2 2 1 2 1 2 2 1 1 2 2 2 1 1 1 2 2 1 1 1 1 2 2 2 2 2 2 2 2 1 1 2 2 1 2 2 2 1 2 1 2 2 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 2 1 1 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 1 2 2 1 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 1 2 2 2 2 2 2 1 1 2 1 1 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 2 1 2 1 2 1 2 1 1 2 2 1 2 1 2 1 1 2 1 1 2 2 2 2 1 1 1 2 1 1 1 2 2 2 2 1 1 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 2 2 1 2 2 1 1 1 2 1 2 2 2 1 1 1 1 2 2 1 2 2 2 2 2 2 1 1 1 1 2 1 2 1 1 1 1 2 2 2 1 1 1 2 2 2 2 2 1 1 1 1 2 2 1 1 2 1 1 1 2 2 1 2 1 2 1 2 1 1 1 2 1 2 2 2 1 2 2 1 1 2 1 2 1 1 2 1 1 2 1 1 2 2 2 1 2 1 1 1 2 2 1 1 2 2 2 1 2 1 2 2 1 2 2 1 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T G G T A G G A T C G T A G C A T G C T A C C A A G G A A G C A T C C T T C G A A G C T A G C T T C C T T G C T T G G T A C G A T C C T A G C A A G G A A C C T T C C A A C G A A G C T A C C T A G C T T G G T A C C T T G C A A G C A A G G A T G C A A G C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T T G G T T C C T T G G T T C C A T G C T A C G A A C G A A G C T T C C A A C G A A G C T A G G A T G C T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A T C C A A C G A T G C T T C G T A G C T T C G A A G G A A C G A A G G T T G G T T C G T T G C T T G C A T G G T T C C A T G G A A G C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T G G T A G C T T G G A A G G T A G C A T G G A A G C T A G G A A G C A A G C T A G G A A G G T A C C A T C G T A C C A T G G T A C G T T G C T A C G T T G C T A C G A A C C T A G C T A C C A T C G T A G G T A C C A A G G A T G C A A G G A A C C A A G G A A G C A A G C T A C C T T G C A T C G T T C C T A C G A A G G A A C C T A C G T T G C A T G G A T C C T T C C T A G G T A C G T A G C A A G C T A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G C A A G G T T C C A T C C A A G C A A C C A A G C A T G C A A G G T T G C A T C C T T C C A T C C A T C C A T G G A A G C T T C C T A G C T A G G A T G G T A C C T T C C T A G G A A G C A T C C A A C C A T C C T A C C A T G C T T C G A A G C T A C G A T G G T A C G T A G G T T G C T A G C A A C C A A G C T A G G A A G C T A G G T A G C A T G G A T C G A T C C T A C G T A G G T T C G A A C G A A C C T A G G A A C G T T C C A T G C T T C C A T G G T A G G A T G G T A C C A A G G T T C G T A C G T A C C T T C G T A G G T A G C T A C G A T C G A T C G T A C C T A C G A A C C T T G C T T G C A T G G A T G C A T G G T T G C A T G G T A C G T T C G T A G C T A C C A T G G A A C C A A G C A T C C T T G C T A C C T T G C T T G C A A G G T T G C T A C C A T C C T T C G A T G G A A G C T T G C A A G C A A C C T A G C A A C G T T G C A A G C A A G C A T G G A A G G A A C G A A G G T T C G A A C G T A C C T T G C T T C G T A G C A T C C T A G C T A G G T T G G T T G C T T C G T A C C T T G G T T C G T T C C T A C C T A C G A A G G A A G C T A C C A A G G A A G C T A C C A T C G T T G C T T C G T A C C T A C C A T C C A T C C A T C C A T C C A T G C A T C C A T G G T T C G T A C G A A G G T A G G T A G C T T G C A T G G A A G C A T C C A T C C T A C C A A G G T T G C T A C C T T C C T A G G T T C C T T C C A A G C T A C G A T G G T A C C A A G C T T C G T A G G T A C C A A G G T A C C T +A G C A A C G T A C C T T C C T A C C T T C G A A G G A A C G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C T T C C T T G C T T G C T A C C A A C C A T G G T T C G T T G C T A G C A T C G T A C G T A G G A A G C A T G C T T C G A T G C A A C C T T C G A T G G T A G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C T A G C T A G C T T G G T A G C T T G C A A G C A A G G A T G C A A G C T A G C A A C C T T G C A A G C T A G G T A G C T T C C T A G G T A G G T A G G T A C G T A G C A T G G A A C G T A G C T A C C A A C G A A G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A G G A A C C T A G G A T C G T A G G T A G G A A C G T A G G A T C G A A C G T T C C A A C G T A C C T T C G T A C G T A G G A A C G T T C G T A G G T T G C T T G C T T G G T A G C T T C G T T C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T T G C T T C C T A G G T A G C T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A A G G T A C C A T C G T A C C T A G G T A C C T T C G A T G G T T G C T A G G T A G C T T G G A A G C A T C C T T C G T A C C A A G C A T G G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A G G T A G C T T G G T T G C T T C G A T C C T T G C T A G G T T G C T A C C A A G C A T G C A T C C T A C G T T C C T T G G T T G G T T G G T T G C A A G C A T C G A A G C T A G C A T C G A A G C A A G C T T G C A T G G T T C G A T C G A A C C T T C G T A G G A A G C A T C G T A G C A A G C A A G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C A T G G T A C G A T G G T A G G T A C G A A C C A A G C T A C G T T C G A A C G A A C G A A G C T T G C A T C C A T C G T A G G T T C G T A C G A A C C T A G G A T G C T T C C A A G C A T C C A T G G A A G G T T G G A A C G A A G G T T C G T A C C T A G G A T C G T T C G A T C C T A C G A T C G A A C C A A G C T A C G A A G G T A G C T A C G A T G G T T G C A T G G T T G C T A G G A A C G T A C G T A G C T A G C T A C G T T C C T A G C T T C G T A C C A A C C T A C C T T G C A A C G T T C C T T C G A T C C A T G G A A G C A A G C T A G C A A G C A A C C T A G G T A C C A A C G T T C C T T G C A T G G T A G G A T G G A T G G A 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C T T G C T T C C T A G C A A C G T A G C A T C C A A G C A A C C T A G C T A G C A A C G T A C C T +A C C A A G G T A C G T T G C T A G C T A G C T A G G T T G G T A G G A A G G T T G C T T G C T T G G A A C G A A C C A A C C T A C C T A C C T T G C A A C C T T G G A T C C A T C C A T G G A A C G T T G G A A G G T T C G T T C G A A G G T T G C A A G C A T C C T T G G T A G C A A C C T T G C T T C C T T C C A T C C A A G C A A G G A T G C A T C C A T G G T A G C T A C G A A G C T T C G T A C C A T G C A A G C A A G G A T G C A A G C T A G G A A C G A T G G A A G G T A G C T A G G T T G G T T G G T T G G T A G G T A G G A T G C A T G G A A C G T A G C T T G C A A C G A A G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A C G T A C G T A G C T A C C T A G C A T C C A A G C A T G G A A G G T A C G A T C G T T C G T T G G T T C G T A C G T A G G A A C G T T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T A C C T A G C A A C C A A G G T A C C T T G G A A G C T A G G A A G C A A G C A T G G T A G G A T G G A A G G T A C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T A C G T A G G T T C C A A G C T T C G T T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G A T G G A T C G A T C C T A C G T A G C T A C C T A G G A A G C T A G C T T G G T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A T G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A A G C A T C G A T C C T T G G A A G C A T G G T A G G T A C C A A C G T A C G A A C G T A G G T T C C A A G G T A C C A T C C A A C C A T C C T A C C T T G C A A C G A A G C T A C G T T C G T T C G A A G G T A C C A A G C A A G C A A G C T A C C T T C C T A G G A A C C A T G C T T G C A A G C T T G G A A G G A A G C T A C G A A C C A A G G A T G C T T G C T A G C A T C G T A G G T A G C T A G G T A G C A A C C A A G C T A G G A T G G A T C G T A G G A T G C T T G C A T C C T T C G T T G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A T C C A A G C A A G C A A C C A A C C T T G C T A G C T A C G T T G C T A C C A T C C A T C G T T G C A A G C T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G C T A C C T T G G T A C G A A G G T T C C T T G C A A C G T A C C A A G C A T G G T T G G A T C C A A G C A A C G T A G C T T C G T T C C T A G G T A G G T T C G T A G C T A C G A A G G A A G C T T C C A T C G T A G C A A C C T A C C A A G G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C C A A C G A A G C T T G C T A C G A T G C T A G G A A C G A A C C T A G C T A C C T A G C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C A T C C A A G C A A C C T A G C T A G C A A C G T A C C T CGU_MN075 # subpop. label: 7 (internally 7) -2 2 1 2 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A G C T T C C A A C C A A G C A A G C A T G C T T C G T T C G A T C C T T C C A T G C A A G C A T G G A A G C T T C C T T G G T T G C A T C C A A C C T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C T A G C A A C C T T C C T A G G A A C C A T G G T T C G T A C C T A C G A T G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G T A G G T T G G T A C G A T G C T A C C T A C G A T G G A T G G T A G G A T G C T T G G A T C C T T C G A T C C T A C G A A G G A A G C T A C C T A C G T T G C T A G G T A G G A T G G T A C G A T C C T A G C T A C C A T G G A A C C A T G C A T C G A A C G A T C C T A C G T A G C T T G G A A G C T A G C A T C C A T G C T T G C A A G G A A C G T A G C T T G C T T G C A A C G A T G C A A G G A A G C A A G G A A G G A A G C A A G C T T C G T A G G A A C C T T C C T T G C A A C G T A G C A T G C A A G C A T G C T T G C T T G C A A G G A A G G T T C G T T C C T A G G T T G C T A G G A A G C A T G C A A G G A A C C T A C C A T C G T T G C A A C G T A C C A A G G A T G G A T C G A A G C A A G G A T G C A A G C A T G G A T C C T A C C A A G G A T G G T A G C T T G C T T G G T A G C A T G C A T G C A A G C A A C G T T C C T A C G T T G C A A G C T T G G A T G C T A G C T A C G T A G C T T C C T A G G A A C C T A G G T A G G T A G C A A C G T CGU_MN076 # subpop. label: 7 (internally 7) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 1 2 2 2 1 2 2 2 1 2 2 1 2 1 1 2 1 1 2 1 1 1 1 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 1 1 1 1 2 1 2 1 2 2 2 2 2 1 1 1 1 1 1 2 2 2 1 2 2 1 2 1 2 1 2 1 1 1 1 2 2 1 1 1 2 1 2 1 2 1 1 1 2 2 1 1 1 1 1 2 2 1 1 2 2 2 1 2 1 1 2 1 1 1 1 2 2 1 1 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 1 2 1 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 1 1 1 1 2 1 1 1 2 2 2 2 2 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 1 2 2 1 1 1 1 2 1 1 2 1 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 1 2 1 1 2 1 1 2 1 2 2 2 2 2 2 1 2 1 1 2 1 2 1 2 2 1 2 2 1 2 1 2 1 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2 2 2 1 2 2 1 2 2 1 2 2 2 2 1 2 2 2 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 2 1 2 2 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 +A G G T A C G T A C C T T C C T T G C T T G C T T G C A A C G T T C C A T C G A T G C T A G C T T G C A T C G A T C G T T G G T A G C T T C G A T C C T A C C T T G G T T G G A T C C T T C G T T G G T T C G T A C G A T C C T T C C T A C C A T G G A T C C T T C C A T G C A A C C T T C G T A G G T T G C T T C C A T C C T T G G A A G G A T C C T T G C A T G G T A G C A A G C A T C G T T C G T A G C T T G C T A G G A A G G A A C C T A C C T T C G A A C G T T G C A A G G T A G C T A G G T T G G T A G G T T C C A T G G A A C C T A G C T T G G A A C C A A G G T A C C A A C G A A G G T T G G A T G C T T C G T T G G A A C C A T G C T A C G A A C G T T G G T A C G T A C C T A G G A T G C A A C C T A G G T A C G T A C G A T G C T A C C T T C C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G 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C A T G C T A G C T A G G T A C C T T C C T A C G A T C C T T G C T A C G A T C G A A G C T A G G T A G C A T G G T T G C A A C C T T G C T A G C T T G C A T G G A T G G T T G C T A C C A T C G T A C C A A C G A A G C T T G G A T C G T A G C A A G C T T C C T A G G T T G G T T G C A T C C A A G C T T C C A T G C A T C G A A G G A T G C T A C G T T C G T T C C A A C G A A C C A A G C T A G G T A G C A A C C T A C G A A C G T T C C T T G C T A G C T A G G T T G C T A G C T T C C A T G C T A C G T A G C A T G G A A C G T A G C T T C C T A C C A T G G T A G G A T G C T T C C T T G G A A C C A T C C A T C G A A C G A A G G A T G C A T C G A A G G T A G C A T C G T A G C T T C G T A C G A T G C A T C G T T C C A A G G T T C G A A G C A A C G T T C G T A G G A A G C T T G C A T G G T T G C T T C G T A C C A A G G A A C C A A G C A T G G T T C C A A G C T A G C T A G G A A C G A A G C A T G C A T G C T A C C A T G G T A C C T T G G A T C C T A G C A T C C T T G G A A G G T A C G T T G G A A C C T A G G T A G G A A C C T T C G A A G G A A G C A A G C T T C G A T G C A A G G T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C T A G C A A G C A A G C A A G C A A C C A A G G T T C G T A G C A A G G T T G C T A C G A A G G T A G C A A C G T A C C A A G C T T G C T A G C T A G C A A C G T A C G T A G G T A C C T A G C A T C C A T C C T T G G A T G C A A G G A A G C A A G C A T C G A A G C T A G C A T C C A A C C A A G C A A G C A T G C T T C G T T C G A T C C T T C C A T C G A T G C A T G G A A C C A A C C T T G C T A C G A T C C A A C C T A G G A A G C T A C C A A G C T T G C T T G C T A G C T T C G A T C G A A G C T A C G T T C C A A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C T A G G T A C C A A G C A T C G A T C C T A C G A T G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C A T G G A A C G T A G G T A C C A A G G T T C C T A C G A T C C T A C G T A G G A T C G T T C G A A C C T T C G T A C C T A G G A A G 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C T A G G T T C C T T G C T A C C T T G C T A G G T A G G T A G C A A G G T T G C T T G C T T G G A A C G A A G C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A T C C A T G G T T C G A T G G T T C C T T G C T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G C T T C C A T G G A A G G T T G G T T G C A A G C T T G C T A C C A T C C A T C C T A C G A A C G A A G C A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C G T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A G G A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T C C T A C C T A G C T T G G T A G G T A C C T T G G T A C C A A G C T T G C T A G C T A G G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T G G A A C G A A G G T A G C T T G G A T G G T T C G A T C C T A G C T A G G T A C G T T G C A A G C T A G C A A G C T A C C T T C C T T C C A T G C A A G C A T G G A A C C A T G G A A G G T T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C C T A C G A T C G A A G C T T G C A A G G T A C C T T G C T A C G A A G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G G T A C C T A C G A A C C A T G C T A C G A A G C A A G G T A C G T T G C T T C G A T C C T T G G A A C G A A G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A C C A A G G T A C C A T G G A T G G T A G G A T G C T A C G A T C C T T C G T A C C T T C G A A C G A T G C A T G G T T G G A A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T A C G T A C C A T C C T T C G A A G C A A G C T A G C T A G C T A C C T T G C T A C G A T G C A A G G T T G G A T G G A A G G A A G C A T G G T T G G A T C G A T G G A T C C T T C C T A C G T T G G T A C C T A G C A T C C T T G C T T G C T A C G T A G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A G C A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G A T G C T T C C A A C C T T G C T A G G A A C C A A C C T T G C T T C G T A G C A T G C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T +A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T C G T T G G T T G G A A G C A T G G T A C C T A G C T A G C A T C G A A C G T T G C A A G C T T C C T A G G T A G C T T C C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C A A G G A T C G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A C C T T C C T A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C G A A C G T T G G T A C G A T C G T A G G T A G C A A G C A A G G T A G G T A C G A T C C A T C C T A G C T T C G A A G G A T C C A T C C T T G C T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G C A A G G T T C G A T G G T T G G T A C C A A G C T A C G A T G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A C C A A C G A A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T T G C T T C G A T C C T A G C T A G C A T G C T T G C A A C C T A C C A T G G T A G C A T C G T T C C T T G C A A G C A T G G T A C C A T G G A A G G A A G C A T G C T T C C A A G C T T G C T T G C T T C G A A G C A A C C T T C C T T C G A T G G T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A T C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T C C A A G C A T G C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T A G C T T G G A T G C T T G C A T G G A A C C T A G G T A C C T A G G T A C G T T C C T A G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C A T G C A A C C A T G C A T C C T T G G T T G G T A C G A T G C T T G G A A C C A A G G T A C G T T G C T T C C A A G C A T G C T A G C A A G G T T G G T T G C A T G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C G A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A C C A T G C T T C G T A C G A A G G T T G C T A C G A T G C T T G G A A G C A A C C T A G C T A C C A T C C T T C C A T C G T T G C A A G C T T G G T T G C T T G C T A C C T A G C A T C C T A G G A A C C T A G G T A G G T A G C T A G C A CGU_MN079 # subpop. label: 7 (internally 7) -2 1 1 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 1 2 1 2 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 1 1 1 1 1 2 1 2 1 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 2 2 1 2 1 2 1 2 2 1 1 2 1 1 2 1 1 1 2 2 1 2 1 2 1 1 2 2 2 1 1 1 1 2 2 1 2 1 2 2 1 1 2 2 2 2 1 2 1 1 1 1 1 2 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2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 2 2 1 1 2 1 1 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 1 2 1 1 2 2 2 1 2 2 1 1 2 1 2 1 1 1 1 2 1 2 2 1 2 1 2 2 2 1 1 1 1 2 2 1 1 1 1 1 1 1 1 1 2 2 2 1 1 2 2 1 1 2 2 1 2 1 1 1 2 2 1 1 1 1 1 1 2 1 1 2 1 1 2 1 2 1 2 2 2 2 2 2 1 2 2 2 1 2 2 1 2 1 2 1 1 1 2 2 1 2 2 2 2 1 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 1 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 2 1 1 2 2 2 1 2 2 2 1 1 2 2 1 2 2 1 2 2 +A C G T A C G T A C G T A G C A A G G T T G C T A G G A A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T A C C T T G G T A G C T T G G T T G C A T G G A A C G A A G G T T G G A A G C A T C G T A C C A A G G A A G C T T G G A T C G T A G C A A G C T T C C T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C C A T G G T T G G A T G G A T C G T T C G T A G C T T G C A A G C A A G G A T G C A A C C T A G G A A C C T T C C T A G C T A G C T A C C T T G G T A G C A T C C A T G C T A C G T A G C T T G G A A C G A A G G T T C C T A C C A A G G T T G G A T G C T T C C T T G G A A C C A T G C T A C G A A C G T T G G T A C G T T C G T A G G A T G C A A C C T A G G A T C G T A C G A T G C A A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A T C C A A G G T A C C T T G G T A C C T A G G T T G C T A G C T A C C T T G G A T G C A A G C T T C G A T G C A A G G T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C A T G C A A G C A A G C A A G C A A G G T A G G A T G C T A G C A T G G A T C C T A C G A A G G T A G C T T C G T T G C A T G G A T G C T A C C T A G C A A C G T T C G T A G G T A G C T A G C A T C C A T C C T T G G A T G C T A G G A A G C A A G C A T C G A T G G A T C G A T G C A A C C A A G C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T G G T A C C T T G C T A C G A A G G T A C C T T C C T A G G T A C C A T G G T T C G A T G C A T G C T T G C A T C G A A G C A T G C T T C C A A C G A T G C T A G C T A C G A A C C A T G C T A C G A A C C T A C G A A C G A A G C T T C G A T C C T A G C A T G G T T G C A A G G A T C C T T C C T T G C A A C C T T G C A T C C A T C G T A C C A T G G T A C C A A G G T T C C T A G C A T G G A A C G T A G G A T C G T A G G A T C C T T C G T A C C T A G G A T G C T A C C T A C G A A C G T T G G A T G G T T G C T T C G A A C G T A C G T A G G A T G C T A C C T T C C T T G C A T C C T A C C A T G C T T G C T T G G A A C G T T G G T T C C A A C C A T C G T T G G A A G C T T C C A A G C A A C C T A G G T A C C A T C G T T C C T A G C A T G G T A G C A T G C A A C C T T G G T A G G A A C G T T C C T T C C T A G C A T C C A A C C T T G C T A G G A T G C T T G C T A C C T A G C T A G G T T C G T T C C T A G C T T G C A A G C T T G C A A G G A A C C T T C G T T C G T T G C T T C C T A C C A A C C A T G C A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C T A G C T A C C A T G C T T G G A A G C A T C C A T C C T T C G A A G C T T G C T T C G T T C C T A G C T T G C T T C C T A C C A A C G T A G C T A C C A A G C A T G C T A G G T A G G A A G G T A C C T +A G G A A C G T A C C T T G C A T G C T T G C T A G G T A C C T T C C T A C G A T C C T T G C T T G C A T C G A T C G T T G G T A G C T T G C T T G C T A G C T T G G T A G C A T C G A T G G T T C G T T G G T A C C A T C G T A C C A A C G A A G C A T G C A A C G T T G C A A C C T T C C A A G G T T G G T T G C A T C C A A G C T T C C A T G C A T C G A T G G T A G C T A G C A T C G T T C G T A G C T T G C T A G G A A G G T A C C T A C C T A C G A A C G T T C C T T G C T A G C T A G G T T G C T A G C T T C C A T G C T A C G T A G C T A C G A A C G T A G G T A C C A A C G A T G C T A C G A A G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C G A A G C T A C C A A G C T A G G T A C G T A C G A T G C T A C C T T C C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A T G C A T G C T A C C A T G G T A C C T T G G A T C C T A G C A T C C T T G G A A G G T A C G T T G G A A C C T A G G T A G G A A C C A T C G A A G C T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G G A T C C A A C C T A G G A A G G A A G G T T C G A A G G A A G G T T C C A A C C A A G G T A C C T T G G T A C C A A G C T T G C T T G C T A G C A T C C T A G C T T G C A T G C A T C C T A C G T T C C T T G G A T G G T A G C A A G G A A C C T A C G A A G C T A G C A T C G T A C C T A C C T T G C T T G G T T C G A T C G T T C C T A C G T T G G A A G C A T G C A A G C A A C C T A G C T A C G A A C C A A C G T A G G A A G C T A C C A A G C T T G C T T G C T A G C T T C G A A G C A A G C T A C G T T C C A A C G A A G C T T C C T A G C A A G C A A G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A A C C T A G G A T C C T T G C T T G C A T C C A T G G T A C G T A G G T A C C A A G C A A G C T T G G A T C C T A C G T T G G T T C G T A C G A T C G T T G G T A C C A A C G T A C G A T G C T T G C A A G G A T G C A A G G T T G C T A G G T A C G T T C C T A G C T A G C A T G G A A C C A A G C A A G G T T C G A T G C T A G G T A G C T A C C T A C G T A C C A T C C A T G G A A G C A A G C T A G C A A G C T T G C T T G G T A C C A A C G A A G G T T G C A T G G A A G G A A G G A T G G T T G C A A G C A A C C A T C C T T C C T A C G T A G C A T G C T T G G T T G G T A G C A A G C T T C C A A G G T A C G T T C C T A G C T A C C A T G C T A G C T T G G A A G C A A G G A A C C A T C G T T G C A A C C T A C G A T G C A T C G A T C G A A G C A T G C A T G C A A C G A A G G A T C G A A C G T T C C A A C C T A G C T T G C T T G C A A C C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C C T A G G T A C C T A G C T A C G T A G G T A G G A A G G T A C C T CGU_MN080 # subpop. label: 7 (internally 7) -2 1 1 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 2 2 2 1 2 2 1 1 1 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 1 2 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 2 2 1 2 1 1 1 1 2 2 1 1 1 2 2 2 2 1 1 1 1 2 2 1 2 1 2 1 1 1 2 2 2 2 1 2 1 1 1 1 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 2 1 2 1 2 1 2 1 2 2 1 1 1 2 1 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 1 1 2 1 2 2 2 2 2 2 2 2 1 1 1 1 2 1 1 1 2 2 2 2 2 1 2 2 2 2 2 1 1 2 2 1 2 2 1 2 2 2 2 2 2 2 1 1 1 2 1 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 2 2 2 1 2 2 1 2 1 2 1 2 1 2 2 1 2 2 2 1 2 1 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 2 1 2 1 1 2 1 2 1 2 2 1 2 1 2 1 2 2 2 1 1 1 1 2 2 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 1 1 1 1 2 1 1 1 1 1 1 2 2 2 1 1 1 2 1 1 2 1 1 1 1 2 1 1 1 2 1 2 2 2 2 1 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C A T G G T T G C A A G G A A G G A A G G A T G G T T G C A A G C A A C C A T C C T T C C T A C G T A C G A A G G T T G C T A G G T A G G A T G C A A C G T T C C A A G C T T G C T A G C A A G C T T C G T A G C A T G C A A G G A A C C T A C C T T C G T T G C T T C C T A C C A A C C A T C C A T C G A T G C T T G G A T G C T A C C A A G C T T C G A A C G A A G C T T G C A A C C A T G C T T G G A A G G A A C C T T C C T A C C A A C C T T G C T T G G T T G C A A G C T T G C T T G C T A G C T A C C T A G G T A G G T A C C T A G C T A G C T A G C A A C G T A C C T CGU_MN081 # subpop. label: 7 (internally 7) -2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 2 1 2 1 2 2 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 2 2 2 1 1 1 1 1 1 1 2 2 1 2 1 1 2 2 1 2 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 1 1 2 1 1 1 2 1 2 1 2 2 2 1 1 2 2 1 2 2 2 2 1 2 1 2 1 1 2 2 1 1 1 1 2 2 2 1 1 2 1 1 2 2 1 2 1 2 1 2 1 1 1 2 2 2 2 1 2 1 2 1 2 2 1 1 1 2 1 2 2 2 2 1 1 2 1 1 1 2 1 1 1 2 1 1 2 1 2 2 2 2 2 2 1 1 1 2 2 2 2 1 1 1 1 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C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G G A A C G A A G C T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G C T A G C T T G C T A C C T A G G A T G C T A C C T A G C T T G G A A C G A A G C T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T C C T A C G A A C G T A G G T A G G A A C G A A C C T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C C A A G G A A C C A A G G T T C C A A C 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C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C T T G C T A G G A A G C T T C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G G A A C G T A C G T A G C T A C C T T C G A A G G A A G C T A C G A A G G T T C C T T G C T T G G T T C G A T C C T T G G T A G C A T C G A T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T G G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C C A T G G A T G G A A C G A A G C T T G G T A G C T T G C A A G 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G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C A T G C T T G G A A C C T A C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T CGU_MN083 # subpop. label: 7 (internally 7) -1 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 2 1 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 1 1 2 2 2 2 1 2 2 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 1 1 2 1 1 2 2 1 2 1 2 1 1 2 2 2 1 1 1 1 2 2 1 2 1 2 2 1 2 2 1 1 1 1 2 2 1 2 1 1 2 1 2 2 2 2 2 2 2 1 1 1 1 2 2 1 1 1 2 2 1 1 1 2 1 1 2 2 1 2 1 2 2 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 1 2 2 2 1 2 1 2 1 1 2 1 1 2 2 1 2 2 2 1 2 2 2 2 1 1 2 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 2 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T C C T A G G A A C C A A G G A T C C T A G G A A G G A A C C T A G C T A G G A A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T T C C T A G C A A G C A T C G T A C C T T G G T A C C T T G G T A C G T A G C A T C G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C T T C G A A C G A A C C A A G C T A C C T A G C A T C G T T C C T A C G A A G G T A G C T T C G T T G C A T G G A T C C T T G C T A G G T A C G T A G C A A G G T A C C T T G G T T C C A T C G T A G G A A C C T A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A A G C T T C G A A C C T T G G A A G C A T C G A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A A G C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C G A A C C A T G G T A C G T A G G T T G C A A C C T T C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C G A T C C A T C G A T G C A A G C T T C C A A G C T T G C T T G G T A C C A A C G T T C C T T G C A T G G T A G G T T C C T A C G T T G G T A C G T A C C T T C C T T G C A A G G T A C G A T G C T A G C A T G G A T G C T T C G T T C C T A G C T A G G T T C G T A G G T A C C T T C G T A G C A T G C A A G G A A G C T A C C A T C C T T G C T A C C A T C C T A C G A T C G A T C C A T C C A T C G A T C G T A G G A T G G T T C G A A C G T A G G A T G C T A C C A T G C T T G G A A G G A T C C T A G C T A C C A A C C T T G C T A C G T T G C A A G C T T G G T T C C A A G C A A C C T A G G T A G C A A G C A A C G A A G C T A C C A A G G T A C C T +T C C A A C G T A C C T A G G A T G G A A G C T A G G T A C G T A G C A A G G T T C C T T G C A A G G T T C G T A G C T A G G T A G C A T C C T T G C T T G C T T G G T A G C A A C G A T C G T T C G T T G C T A C C T T G C T A C C A A C G A A G C T T G C A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T G C T A G C A A G G A T G G T T C C T T G G A T G C T A C C A T C G T T C G T A G C T T G C A A G C A A G G A T G C T A G C T A G C T A C C T T G C T A G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T C G A T G G T A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T T G G A A G C T T C G A A G G T A C C A A G C A T G G A A C G A A C G A T G C A A C G T A G G T A C C A A G G T T C C T T C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T C G A A C C T A G C T A G G A A G G A A G C A A G C A T G G A A C C A T G C A A C G T T G C A T G C A A G G T A G C T T G C A A G G T A G C T A G G A A G C T T G G A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A G G T A G G A A G C A T G G A T G C T T C C T A G G A A G G T A G C T A C C T T G C A A G G T T G C T A G G A A G G T T G C A T C G A T G G T T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T A G C A A G C T T G C A A G C A A C C A T G C T A C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C A T C G A A C C T A C G A A G C T T G C T A G G T A G C A A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C T A C C T A C G A T C C T A G G A T G C T T G G A A C C T T C G T A G C T A C G T A G C T T G C T A G C T T G G A T G C A T C C T T G C T T G G T A C G T T G G A T G C T A G C T T G G A A C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G T T G G T A C C A T C C T T C G A T G C T T G C T A G C T A G C T T G G T A G G A A C C A A G C A A G G T T C C A T G G A A G G A T G C T T G G A T G G T A G G A A C G T T G C T T G C A A C G T T G G A A C C T A G C A T C C T T G G A T G C T A C G T A G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A A C C T A C C A T C G T T G C T T C C T T C C A A C G A T C G A T C G A T G C A T C G T T G C T A G C A T G C T A G C T A G G T A G G A T G C T A C C T T G C T A G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G G T T C C T T G C T A G C A A C G T A G C A T G G A A G G A T C C T A G C T A G C A A C G T A C C T CGU_MN084 # subpop. label: 7 (internally 7) -2 1 1 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 2 2 2 2 2 1 1 2 2 2 1 2 1 2 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C A A G G A A G G A A G C A T C G A A G G A T C C A A C G A T G C A T C C A A G G T A G C T A G G T T C C T A C C T T C C A T G G T T C C T A G C A T G G A A C G A A G G T T G C A A C C T T G G T T G G A A G C T T G C T A G G A A C C T T C C A T C C A A G C T A C G A A G C T A C G T A G G T T G G A A C G T T G G A A C G A A C G A T G C A A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G C A A C C T A G G T A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C T T C G T T G C A A C C A A G G A A G G T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G T A G C T T G G A T G C T T G C T A G G T A C G T A G G A A G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T A C C T A C G T A G C A A C C T A C G T T C G A A G C T A C C T T G C T A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A T G C T T G G T T G G A T G C A T G G T T G C T A G G T A C G T T C C T A G C T A G C T T C G A A C C A A G C A T C C T A C C A A C C T A C G T T G C A A G G T T G C T T G C A T C C T T C G A T G C A A G C T A G C A A G C T T C C T T G C A A C C A T G C A A G C A A G C A T G C T T G C A A C C A A C G A T C G T A C G A A C C T T G C T T G C A A G G T A G C T A G C A T C C T T G G A T G C A A G C A A C G T T G G T T C G T T C C T A G G T T G C T A G G A A G C A T G C A A G G A A G C T A C C A T C G T T G C A A G C T A C G A T G G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C C T T C G T A G G T A C C A A G C A T G C T T G G A A G C A A C C T A G C T A C G A A G C T T G C T T C C T T G C A A G C T T G C T T C C T A C C A A C G T A G C A A C C A A G C A A C G T A G G T A G G T A G C T A C G T +A G C T A G G T T C G T A G C T A C C T T G C A A G G T A C C T A C C A A G G A T G C T T G C T A G G A A G G A A G C T T G G T A G C T A G G A T G C A A C C T T G C T A G C A T G C T T G G A T C C T T G G T A G C A T G C T A G C A A G G T A C G A T G C T T C G A T G C T A G C A T C C A A G C T T G G T A C C A T C C A A G C A T C C A A C G T T C C A T G G T A G G A T G C A T C G T T C G T A G C T A G C A A C G A T C G A A G C T A G C T A G G A A C G A T G G A T G C T A C G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T G G A T G G T A G G T T G G T T G C T T G C A A C C A T G C A A C C A A C G T T C G T A C G T A C G A A C C T A C C A A C G T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G T T G G T T C G T A C G A A C G A A G C T T G C A T G G T T C G T T C G T T C G A A C C A A G G A T C C T T G G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G G A T C C T A G C A T C C T T G G A A G G T A C G A T G G A A G G T A G G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A A C G T A G G T T G G A A G C A T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T C G A A C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G C A A G G A T G C T A C G A T C C T T C G A T G G A A G C T A C C T A G G T T C C T T G G A A C C A T G C A A G G T T G G T T G G A A G G A A G G A A C C T T G G A T C G A A C C T T C C T T G C A A C G T T G C T A G C A A C G A T G C T A G C A A C G T T C C T T G G T T C G T T C C T A G G T T G C T A C G A A G C A T G C A A G G A T G C T A C C A T C G T T C C T A G C A A C C T A G C A T C G A A G G A T C C T A G G A T G C A A C C A T G G A T C C T A C G A T G C T T G C T A C G A T G C T T G G A A C C A T C C T A G C A A C C A A C C T T G C T A C C T T G G T A G C T T G C T T C C A A G C T A C C T A G C T A C C A A G C A T G C A T G G T A G G A T G C T A G G T CGU_MN085 # subpop. label: 7 (internally 7) -1 2 2 1 2 2 1 1 1 1 1 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 2 1 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 1 2 1 1 1 2 1 2 2 1 2 1 2 2 2 2 2 1 2 2 1 1 1 2 1 2 1 2 2 1 2 1 2 2 2 2 2 1 1 2 2 1 2 1 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 1 2 1 1 2 2 1 1 1 1 2 2 2 1 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 1 2 1 1 2 2 1 1 2 2 1 1 2 2 2 2 2 1 2 1 2 2 1 1 2 2 2 1 2 1 2 1 1 1 1 1 2 2 1 1 1 1 2 1 2 1 1 1 1 2 2 2 1 2 1 1 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 1 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 1 2 2 2 1 2 1 1 2 1 1 1 2 2 1 2 2 1 2 1 1 2 1 1 1 2 1 2 2 2 1 2 1 2 1 2 1 2 2 2 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 1 1 2 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A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T T C G A T C C T T C G T T C C A A G G A A C G A A G C A A C C T T G G A A C C A T G C A A G C A A G C A A G G A A G G A T C G A A C C T T G G T A G C A A C C A T C C T T G C A T G C A T G C A A G C T T G C T T G C T A G G A A G C T T C C A T G G T T C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C C A A C C A A C C T T C C A T C C A T G C T T G G A T G C T A G C A T G C T A G C T A G G T A G C T T G C T A G C A T G C T T G G A A G C T A C C T A G C T A C C T A G G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN086 # subpop. label: 7 (internally 7) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 1 1 2 1 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 1 1 2 1 2 1 2 2 1 2 1 2 1 2 1 2 1 2 1 2 2 2 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T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T C C T T G G T T G C A T G G A T C C T T G C T A G C T T G C T T G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C C A T G G A T G G T T C C A T C C A A G G A A C C T A G C T T G C T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T C G T A C G T A C G A A G G T A C C T A C C T A C C A T G C T A G C T A G C A A G G A A G C T T C C T T G G A T G G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T G C T A G C T T G C A T C C T A G G T A C G T A G G T A C C A A G C T T C C T A G G A T G G A T C C T A G G A T G C A A G G A T C C T T C G A A G C T A C G A A G C T T G C T T G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T A G G A A C C A T G G T T C C T A G G A T G G T A G G A A G C A T G G T T G G T T C G A T C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T T G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T T G C T A G C A T G C T A G C T A G C A A C G A A G G T A G G A T G C T T G G T T G G A T G C T T G G T A G C T A C C T T G C T T G C A T G G T A G C T T C C A T G G T T C C T A G C T A C C A T G C T A C C A A G G A A G C T T G G A A C G A T G C A A C C T T C C A A G G T T G G T T C C A A C C T A G C A T C C A T C G T T C C A T C G T A G G A A C G T A G G T T C G T A G C T T G C A A G C T A G G A T G C A A C C T A G C T A G C T T G C T A G C T A G C T A C G T T G G T A G G T T G G A T G C T A C G T A G G T T G G A A G G T A G G T A C C A A C G A A G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G A A G G A A C G A A G G T A C C A A C G T A G G T A G G T A C G A T G C A A G C A T G C A A G G A A C G T A G C A A G G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G G A T G G T T C G A T G G A A C C T A C C T A G C T A C G T A G C A A G C A T G C A T G C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A A G G T A C G A T G G A A G G T A G G A A G C A A G C T A G G T T C C A T G G A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C T T G G T T G C T T C G A T C C T T G C T A G G T A C C T A G G T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T G C A T G G T A C G A T G G T A G G T A C G T A C C A T G C T A C G A A G C T A G G T A G C A T C C T T G C A A G C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G C T A C G A T G G T A C C A A G G T T C C T A G G A A C C A T C G T A G G A T G G T T G C A T C C T A C G A A G C T A C G A A G C T T G C T T G C A A C G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T A G G A A C C A T G G T T C C T A G G A T G G T A G G A A G C A T G G T T G G T T C G A T C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T T G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN090 # subpop. label: 7 (internally 7) -2 2 1 1 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 1 1 2 1 2 2 2 1 1 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 2 1 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 1 1 2 2 1 1 2 2 1 1 1 1 1 2 2 2 2 2 1 2 1 2 2 1 2 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 1 1 1 1 2 1 1 1 1 2 2 1 2 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G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G C A A G G A A G C A T C G A A C C T A C C A A G G A A C G A A G C A A G C A T G C T A C C A T G G T A G G T T G G A A C C T T G C A T C C T T G G T A G G T A C G T T G G T A C G T T G G T A C G T A G C A A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G T T G G A A G C A T C G A A G C A A C C A T G C T A C G A T C C T T C C T A C C A A G G T A C C T T C C T A C C A T G C T A G C T A G C A T C C A A G C T T C C A T G G A A C G A A G C T A C C T A C C A A G C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A A C C T A C G T A C G T T C G A A G G A T C C T T C C A A C G T T G C A T G C T T C C A T G C T A C G A T G G T A C C A A G G T T C C T A G G A T G C A T C G T A G G A T G G T T G C A T C C T A C G A A G C T A C G T A G G T T G G T T G G T T G G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C T A C C T T C C T A G G A A C C A T G G T T C C T A G G A T G G T A G G A A G C A T G G T T G G A T C G A T G G T T C C T T C C T A G G T A C C T A C C T A G C T T G G A T G G A A G C T T C C T A G C T A G G T T C G T T G G T A C G A T G G A A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T C C T A G G A A G C T A C C T A G C T A C G T A G C T T C C T A C G T T G C A T G C T T G C T T G C T A G C A A C G T A G C A T G C A A G C A A C C T A G C T A G G A A G C T A G C T +T G C A A G G A T C G T T C C T A C C T T C G A A G G A A C C T A C C A A G G T T G C T T G C T T G G T T C G A T C C A T G G T A G C A T G C A A C C T A C C T T G G T A G C A T C C A T G G T T C C T T G C T A C C T T G C T A C G A A G G A A C C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A G C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C G T A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C T A G G T A C C A A C G T T G G A A G G T A C G A T G C A T C G T A G C A A G G A A G G T A G C A A G G T T G G A T C G A A G C T T G C A T G G T A G C T T C C T A G C A A G G A A G C A A G C A T G G T A G G A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T C C T A G G T A G C A A G C A T C G T A C C T T G G T A C G T A G G T A G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C A T G G A T G C A A C G T A G C T A G C A A G C T A C C T A G C A A G G T A C C T A C G A A G G T A G C T T G G T A G G A T G G A T C C T T G C T A G G T A C G T A G G A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A T C G A T G C A T C G A A G C A A C C T T G C A A G G A A G G T A G C T A G G A A C G A T C G A T G G A T G G A T G C T A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C A T C G A A C C T A C G A A G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T A C G A A G C T T G C T T G C A A C G T A C C A T G G T A G C T T C G A A C C T T G G A T G C A T G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C G T A C G T A C C A T C C T T C G A T G C T T G C T A G C A A G G T T C C T A G G A A C C A T G C A A G C A T G C A T G G T A G G A T C C T A G G T T G G T A G G A A C G T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T A G G T A G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G A A G C A A G C A A C C T A C G A T C G A T C G A A G C T T G C T T G C A A G G A T G G A T C C T A C G A T G C T T G C T A C C A T G C T T G G A A G C T T C C T T G C T A C C A A C C A T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN091 # subpop. label: 7 (internally 7) -1 2 2 2 2 1 1 2 2 1 1 2 2 2 2 2 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A G G T A G C A A G G A A C C T T C G T T C G T T G C T T C C A A C C A A C G A T G G A T C C A T C C A T C C A T G C A T G C A A G C T T C C T A C C T T C C A A G G T A C C A A G C A T G C A A G C T T C C T A C C A A G C T A G C T T G G A T C G T T C G T A G G T T C C T T C C T A G C A A C G T A G C A A C C A A G C A A C G A A G C T A G G T A G C A A C C T CGU_MN092 # subpop. label: 7 (internally 7) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 1 1 2 1 1 1 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 2 1 2 2 1 2 1 2 1 2 2 1 2 1 2 1 1 2 1 2 1 1 1 2 1 2 2 1 2 2 2 1 1 2 1 2 2 2 1 2 2 2 1 1 2 1 2 1 1 2 2 2 1 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 1 1 1 2 1 1 2 1 1 1 2 1 2 2 2 1 2 1 2 1 1 2 2 1 1 1 1 1 2 2 1 1 1 2 2 2 2 1 1 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 1 1 1 2 1 1 1 1 2 1 1 2 1 1 1 1 1 2 2 2 1 1 1 1 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C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A G C A A C C A T C G T A C C A T G G A A G C T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C A A C C T A C C A T G C A A C C A A C C T T C C A T G G T T G G A A G C T A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C A T C C A T C C A T G G A A C C A T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T C C T A C C T A G C T T C G T T G G A A G C T A C C T A G G T T C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A C C T A C C A T C G T T G C A A C G A A C G A A G C A T G G A T C G A A G C A T C G T T G C T A G G A T G G A A C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T C C T A C G T T G C A A G C T T G C T T C C T A C C A A C G T A G C A A C C A A G C A T G C A T G G T A G G A A G C T A C G T +A G G T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A G C A A G G T A G G A A G C A A C G A T C G A T G C A A C C T A G C A T C C A A C C T A C C T A G G T A G C T T G C T T G G A T C C T T G C T A C C A T G G T A C G A A G G A A C C A T G C A A C G T T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G G A A G G A T C G T A G C T T G G T A G C T A G C A A G C A A G G T A G C A A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T A G G T A C C T T C C A T G G A A C G A A G G T A C C A A C G A A G G T T G G A T G C T T G G T T G C A A C C A T C C A A C C T A G G T A G G T A G G A T C G A A G G T A G C A A G C T A G G A A C G T A C G A T G C T T C G T A G C T T C G T A C G T A G C A A G G T T G G A T C G A A G C T T G C A T G G T A G C T T C C T A G C A A G G A A G C A A G C A T G G T A G G A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A C C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C A T G G T T G G A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C A T G G A T G C T T G C A A G G A A G C A A G C T T C C T A G C A T C G T T C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G G A A G G A A G G A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A T C G A T G C A T C C A A G C T A C C T T C C T T G C T T C C A T C C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T T G G T A G C A A C C A A C C T T G G T A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C G T A G G T A G C A A G C T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T T C C A T G C A T C C T A C C T A C C T A C G T A G C A A G G T T C C T T C C T T C C A T C G T T G G A A G C T T C C A A G C A A C C T T G C A T C G T T G C A A G G T T G G T T G G T A G G A A G C A A C G T T G G T A C G T A C C T T C C T T C C T A G C A T G C A A C C T A G C T T G G A T G C T T G C T A C G T T G C T A C G A A C C T A G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A G C A A G C T T C C T A C G A A G C T T G C T A C C A T G C T T G G A A G C T T C C T T C C T A C G T A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN093 # subpop. label: 7 (internally 7) -2 2 2 2 2 1 1 2 2 1 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 1 2 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 1 2 2 2 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C T A C C T T G C A A G G T T G G T T C C A A G G T T C C T T G C A A G G A T G G A A G C T T G G T A G C T T C C T T G C A A C C A T G G A T C C A T C C A T C G A A C G T T G G A A G C A T C G T T C G T A G C T T G C A T G C A A C G A T G C A A G C T T C G A T G G T A G G T T G C A T C C T A C C A A G G A A C C A T C C A T G G T A G C T A G C A T C G T T C G T A G C T T G C A A C C A A G G A T G C A A G C T A G C A A C C T T G C A A G C T A G G T A G G T T G C T A G C T T C C A A G G T A C C A T G C T T G G A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C T A C C A T G C T A C G A A C G T A C G A T G C T A C C T A C G A T G C A A C G T A G C A T C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A G G T A G C A T G G T A C G T A G G A A G C T A G C T A C C T A G G T A C C A A G C T T C C A T C C A A G G T T G C T T C G T T G C A A G G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T A G G A T G C A T C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T A G G A A G G T A G C A T G G A T G C T T C G A T C C T A G C T A G C T A C C T A G G A A G G A A C C T A G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T G C T A C G A A C G A A G C A A G C T T G C A A G G T A G C T T G C T A C G A A G C T T C C T A G C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A A G G A A G C T T C C A T G G T A C G A T G G T A G G T A G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A A G C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T A C G T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A T G G T T G C T A C C A T C G A T C G A A C G A A G C T A C C T T C C T T G G T A G C A A G C A T G C A A G C T T G G A T G G T A G G A A G C A A C G A T C G T T C G T A G C T T C C T T C C T A G G T A C G A A C C T A G C A T G G A T G C T T G C T A C G T A G C T T G G T T C G T T C C A A G C A T G C T A G C T A C C A A G G A A G G A T C G T T C G T T G C A A C C A T C G T A C G A T C C A T C G A A G C A A G G A T G C T A C G A T G G A T C G A A C G A T G G T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C T A G C T A G C A T C G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G G T A G G A T G C T A G G A T G C T A G C T A G G T A G C T T C C T A G G A T G C T T G C T T G G A A G G A A C G T T G G T A G C A T G C A A C C A A C C T T G G T A G C T T C C T T G G A T C C T T G G T A G C A T C G T A C C T A G G A A C C A T C C T T C G A T G C T A G C T T C G T A G G T T G C T A C C A T C C T A G C A A G G A A C C T T G C A T G G T A G C T A C G A T G G T T C G T A G C A A G C A A C G A A G G T T G C T A G C T A G G A A C C A T G C A T G C T A G C T A C G T T C C T A G C T T C C A A G G T A G G A T G C T T G G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A G C T T C G A A C G A T G C A A C G T A G G A T C G T A C G A T G C A A G C T T G C A A G C A A G G T T C C A T C G A T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C C T T G G A T G C T A G C T A G C A T C G A A G G T A C G A T G C A A C G T A G G A A G C T T C C A A G G T A G G T A C C A T C G T T C G A T G G T A C C T T G C A T C G T T G C A A G G T T G G T T G G A A G C T T C G T T G G T A C C A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T G G T T G C T T G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T A C G T T C G A A C G A A G C T A C C A T G C A T C G A T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T T G C A T C G A A G C A T C C T T G G A T C G A T G G T A C C T A C G T A G C A T C C T A C G A A C G A A G G T A C C A T G C T T C G A T C C T A C G A A C G T T G C T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C G T A C C T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C T A C G A T C C T T C G A T C C T A G G A A C G A T G C T A C C T A C G T T C C A T C C T T G C T A G G A A C G A A C C T T C C T A C C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C T T G G T T G C T A C C A T C C T A G C A A G G A A G C T A C C A T G C A A C G T A G C A A C G A T G C A A G C A A G C A T G G A A G G A A C C A A G C T T G G T A G G A T G G A T C C T T C C T A C G T A G C A T G G T T G C T T G G A A G G A T G C A A C G T T C C A A G C T T G C T A G G T A G C T T C G T A G C A T G C A A G G A A C C A A C C A T C G T T G G T A C G A A C C A A C G A T C C A T C C A T G C T T G G A T G C T A G G A T G G A T G C A A C G A T G C T T G C T A C C A T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C C T A G C A A G G T A C C T A G C T A G C T A G C A A C G T A C C T CGU_MN095 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 2 2 1 1 2 2 1 1 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 1 2 1 2 1 2 2 1 2 1 2 2 2 2 2 1 2 2 2 1 2 1 1 1 1 2 2 1 2 1 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 2 2 2 1 1 1 1 1 2 2 2 2 2 2 2 1 1 1 1 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T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C G T A C G A T G C A A C G T A G G A T C G T A C G A T G C A A G C A T G C T T C G A A C G T T C C A T C G A T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A C C A A G G A A G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C C T T G G A T G C T A G C T A G C A T C G A A G G T A C G A T G C A A G G T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T A C C T A G G A A G G A A C C T A G C A T G C A T C C T T G G A T G C A A G C A T G G T T C C A T G C A A G C T T C C A T C G A A G C A A C C T T C C T T G C T T C C A T G C T A C G A A C G T A G C A A G C T T G C T A G C T A G C A A G G T T C G A T C C T A C G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C C A A C C A A G C T T G G A A G G A A C G A A C C A T G C T T C G A A C C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T C C T T C G A A C C A T G G T A C G T A G G T A G C A A G C T A C C T A C G A T G G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T A C C T T G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A T G G T T G C T A C C A T C C A T C G A A C G A A G C T A C C A T C C T T G C T A G C T A C C A T G C A A G G T T G C A T G G A A G G A T C G A A G C A T C G T A G G A A G G A T C C T T G C T A C G T T G C A T G C T A G C A T G G A T G C T T G C T A C G T A G C T T G G T T C G T A C G T A G C T T G C T A G C T A G C A A G G A T G G A A C C A T C G T T G C A A C C A T C C T A C C A T C C A T C G A A G C A A G G A T G C A A C G T T G G A T C C T A C C A T C G A T G C T A C C T A G C A T C C A A G C T T C G A T C G A A C C A A C C T A G C T T C C T T C C T A G C T T G C T T G C T A G C A A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G G T A G G A T G C T A G G A T G C T A G C T A G G T A G C T T C C T A G G A T G C T T G C T T G G A A G G A T G C T T G G T A G C T A C C T T G C A A C C T T G G T T C C T T C C A T G G T T G G T T G G T A G C A T C G T A C C T A G G T A G C A T G G A T C G A T G C A A G C T T C G T T G C T T G C T A C C A T C C T A G C A A G G A A C C T T C C A T G G A A G C T A C G A T C G T T C G T A G C T T G C A A C C A A G G T T G C A A G C T A G C T A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C T A C C A T G C T A C G A A C G T A C G T A G C T T C G A A G G T A G G A A C C T A G G A A G G T A C G A T G C T A G C T T G C A A G C A A G G A T C C A T C G A T G C T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G T A C G T A G G A A G G A A C C T A G G T A G G T A C C A A G C T T C G A T G G T A C C T T G C A T C G T T G C A A G G T A G G T T G C T T C C T T C G T T G G T T C C A A G G A T G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T G G T T G C T A G G A A G G T A G C A T G G A T G C T T C G A T C C T T G C T A G G T A C C T A C C T T C C T A C C T T G C A T G C A T C C T A C G T T G G A A C G A A G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C T T C G A A C G A T G G A A C C T T G G A A G G T A G C T T G C T A C G A A G C T T C C T A G C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A T C G A A G C A T C C T T G G A T C G A T G G T A C C T T G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A A G C T T C G A A C G A A G C T A C G A A C C A A G G A T G C T T G C T T C C T T C C A T G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T T C G T T G C A A G G A A C C T T C G T A C C T T C G A A G G T T G C T A C G A T G G T A C C T A G G T T G C T T G G T A C G T T G G A T G C A T G C A T G G T A C C A T G C A T C G A A C C T T C C T A C G T T G C A A G G A T G C T A C C A T C G A T G G A A G G A A G C T T C C A A G C T T G G T A G C A A G C A T G C A T G C T T G C A A G G T A G G A A G C A T G C A T G G T A G G A T G G A T C C T T C C T A C G T A G C T A C C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T T G G T A C G A T G C A A G C T A C C A A G G A A G C A T C C T T C G T T G C A A G C A A C G T A C G A T C C A T C G A T G C T T G G A T G C T A G G A T G G A T G C A A C G A T G G T T G C T A C C A T G C T T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C C T A G G T A G C A A G C A A C G A A G C T A C C A A G G T A C C T CGU_MN096 # subpop. label: 7 (internally 7) -2 1 2 2 1 2 1 1 1 2 1 2 1 1 2 2 2 1 2 2 2 2 2 1 2 2 1 1 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 1 2 2 1 2 1 2 2 2 2 1 1 2 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 2 1 1 2 1 2 1 2 2 2 2 1 1 1 1 2 2 1 1 2 2 2 1 1 1 2 1 1 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 1 1 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 1 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 1 2 1 1 2 1 2 2 1 1 2 1 2 1 2 2 2 1 2 2 2 2 1 2 2 2 2 1 2 2 2 1 1 1 2 1 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 1 2 2 2 2 1 1 1 1 2 2 2 1 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 2 1 2 1 1 2 1 2 1 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 1 1 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 2 1 1 1 2 2 2 2 2 1 1 1 1 2 2 1 2 1 1 2 1 2 1 2 2 1 2 2 2 1 1 2 2 1 1 2 2 1 2 2 1 1 2 1 2 2 2 2 2 1 1 2 2 2 1 2 2 2 1 1 1 2 2 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C T A G C T A G C A T C G A T G G T A C G T T G G T A G C A T C G T A C G T A G G A T G G A T G C A A C G T T G C A A G C T T C C T T G G T T G G A T C C A T C C T A G C A A G G A A C C A T C C T T G G A T G C T A G C A T C G T T C C A A G G A A C C A A G C A A G C T T G C T A C C T A C G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T T G C T A C G A T G C T T G G A A G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C C T A C C T A C G T A C C A A C G T T C C T A G G T A C G A T G C T T C G T A G C T T C G A A G G T T C C A A C C T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C C T A G C A T C C T T G C A T C C A T G G A A C G T A C C T T G G T A C C T A G G T A G C A A G C A A G G A A G G T A C C A T C G A T C C A A G G T A C C T T G C T A C G T A G C A A G G A A G G T T G G A A G C T T C G T T G C T A C C A A G G A T G C A A G C A A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G C T A G G A A G G T T G C A T C G T T G C A T G G A T C C T A G C T A G C T T G C T A G C A A G C T A C C T T G C A T G C A T C G T T C C T T G C A A G C A T G G T A C C A T G C A T G G T T G G A T C C A A G G A A C C T A C C A A G C T T C G A T C C T A C G A T C G T A G C A A G C T T G C T A G C A T C C T T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A T G G T A G G T A G G T A G C A T G C T T C G T A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G G A T C G T A C C T A C G A A G C T T G C T T G G A A G G A T G C A T C C T T G C T T G G T A C G T T G G A T G C T A G C A A G G T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T G G T T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T A C C T T G G A A C G A T G C A T G C A T G G A T G G T A G G A A G C A T G G T T G G A A G G T A C G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A A G C T T C G A A C C T T C G A A C C T A G G T A C G A T G G A A G C T A G C A A G G A A C C A A C G A T C G T T G G T A G C T A C G A T C G A T C C A T C C A T G C T T G G A T G C T A C C A T G G T A G C T A G G T A G G A A G C T A C C A T C C T T C G A A G G T A C C T A G C T A C C A A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T +T G C T T G G A T G C T T C C T A C C T T C G A A G G T T G G T A C G A A G G T T G G T T G C T T G G T T C G A T G C T A G G T A G C A A G C A A G C T A C C T T G G T A G C A T G C A T G G A T C C T T G C T A C C A T C G T A C G T A G G T A G C A T G C T A C G A T G C T A G C T T C C T T G G T T G C T T C C A T C C T A G C T T C C A T C C A T C C A T G G T A G C T A G C T A G G T T G G T A G C T T G C T A C G A A G G T T G C T A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A A G C T A G G A T G C T T C C T T G C A T C C A T C C T A C G A T C G T T G G T A C G T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C T T G G A A C C T A C G T A G C A A C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A C C A T G C T T C C T T G G A T C C T A G G T A G C A T C C A A C G T A C C T T G G T A C C T A G C A A G C A A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G C T A G G T T C G A T G C T A G C A T C G T T C C T A C C A A G G T T G C T T G G T A G C T T G G A T C C T A G C T A G C T A C C T A G G A A G G A A C C T T G C A T C C A T C C T T C G T T C G A A C G A A G C T A C G A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A A C C T A G C A A G C A T C C A A G C A A G C T T G C T A C G A A C C T T C C T A C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C A T C C A T G G A A C G A T G G T A C C T A C G T A G C A A C G T A C G T T C G A A G C T A G C T T G C T A G C A T G C T T C G T A G G T T C G T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T A C G T A G G A A C C A T C C T A C C T A C G A T G G A T C G T A G C A T C G T A C G A T C G A T G G A A G C T A C G T A G C T T G G T A C G T T G G A T G C A T G G T A G G A T G G A A C G T T C C T A C C T A G C A A G G A A C C T T G G A T C G A A C G A A C C T A G G T A G C T A C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G C T T C C A T G C A A C G A T C C A A G G T T G G T T C G T A G G A T G C T A G C T T C G T A G G A A G G T T C C T T G C A A C G T T G C A A G C T A G C T T G G A T G G T T G C T A C G T A G C T A G G T T G G A A C C A A G G T A G C A A G C T T G C A A G G A A G C T T C C A T C G T T G C A A C G A A C C A A C G A T C C A T C C A T G C T T G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C T A C C A T G C T T G G A A G C A A C C T T C C T A C C T A C C T A G C A A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G C A A G C A A C G T A G G T A G G T A G C A A C G T CGU_MN097 # subpop. label: 7 (internally 7) -2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 2 1 1 2 2 1 1 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 2 1 2 2 1 1 2 2 1 1 1 2 2 2 1 1 2 1 2 1 2 2 2 2 1 2 1 2 2 1 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 1 2 2 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 2 2 1 2 1 2 2 2 1 2 1 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 1 1 1 1 2 2 1 2 1 2 2 2 1 2 2 1 1 1 2 1 2 2 2 1 1 1 2 1 1 1 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 1 1 1 2 2 1 1 2 2 2 2 1 2 1 2 1 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A G G T T C C T A C G T A G C A A G C T A G G A A C G A A G C T A C C T T G C T T C C A A C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T A G G T A G C A A G C T A C C A A C G A T C G T T G G T A G G A T G C A A G G A T C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T G G T T G C T A G G A A C G T T C C T A G C T A G C A A G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T G G T T C C A T C C T T C G A A G G A T G C T T C C T A G C T T G G T A G C T A C G A T G C A T G C A T G G A T G G T A G G A A G G A T G C A T G G T A G C A A C C A T C G T T C C T A C G T T G G T A C C T A G C A T C G T T G G A A G C T T C C T A C G T T C G T T C C T T G C T T C G A T C G T A G C T A G C A A G C A T C C T A G G T T C G A A C C A A C C T A C C T A C G T T C C A T C C A T C C T A G G T T C G A A G C A T G G A T G C T A C G T A G G A A C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G G T A C C T T C C T T G G T T G C T T G C A A G C A T C C T A G C T A C C A A G C A T C C T A G G T A G G T A G C A A C G T +A C C T A G G T A C G T T G C T A G C T T C G A A G G T A G C T T C C T A G G A T G C T T G C A T G G A T G G A A C G T T G G T A G C T A C C T T G C A A C C T T G C T A G C A T C G A T G G T T C G T T G C T A G C A T C G T A C C T A G G A A C C A T G C T T C G A T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A T C C A T C G A A G G A T G G A A C G T T C G T T C G T A C C T T G C A A G C A A G G T T G C A A G C T A C C A A C G T T G C A A G C T A G G T A G G T T G G T A G C T T C C A T G C T A C C T A G C T T G G A A G G T A G G T T C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C A A C C A A C G T A G G T A G C A A C C T A G G T A C C A A G C T A G G A A C G T A C G A T G C T A G C A A C C A T C G A A G G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G A A G C T A G G A A G G A A C G A A G G T T C C A T G G A T C G T A C G A T C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A G C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G G A A G G A A G G T A G C A A C G T T G C A T G G A T C C T A G C T A G C T T G C T A G C A A G C T A G C T T G C A T G C A T C C T T G G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G C T A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C C T A C G T A C C A T G C A T C G A A C C T A C G A A C G T T G C T A C G A A C C T A C C A T C C T T G C T A G C A T C C A T G G A A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G C A T G C A T G G T A G C T T C G T A C C T A G C T T G G A A G C T A G C T T G G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T C C A A G C T T C C T T G C A T G G T A C G A A C C T A C C T T G C A T G G T A C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T A C C T T G G A A C G A T G C A T G C A A G C A T C G A A G G A T C G A T G G A A C G T A G G A A C C T T C C T T G C A A G G T T G G T A G C A T C C T A G C T A G C A A G C T A C C T A G C T A G G T T C G T T C C T T G C T A G G A A G C A T G C A A G G A A C C T A C C A T C G T T G C T A C G A A C C T A G G A T C G A A G G A A G C T A G G A T G C A A C G T T C G A T C C T A C C A A G G T A G G T A G C A T G C T T G G A A G C T T G C T T C C A A G G T A G G T T G C A A C C T T C C T A G G A T G C T T C C A A G C T A C C T A G G T A G G T A G C A T C G T A G G T A G G T A G C T A C G T CGU_MN098 # subpop. 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G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C G T A G G T A G C A T G G A A G C T A G G A A G C A A G G A T C G A T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G G A T G C A A C G A A C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A T C G T A G C A T G G A T G C T A C C T A G G T A C G T A G C A A G C A A C C T T G C A T C C A T C C T T C G T T G C A A C C A T G C T A C C A T G G A A G G T T G C A T C C A A C C A A C C T T C C T T G C T T C G A T C G A A C C T T C G T A G G A A G C T T C G T A G C A A C C A T G C T T C G A T G G T A C C T T G C T T G G T A C G T T G C T T C C A T G C A A C C T T G C A T C G A A G C A T C C T T G C A A C C A A G G T A C C T A C G T A G C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T A C G A T G G T T C C T A G C A A C C T A G G A T C C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G C A A G C T T G G A T G C T A C G T A G G T A G C A A C G A T C G A T G G A A G C T A C G A A G C T T G C T A C C T A G G T A C C A T G G T T G C T A G G A A C C A A C C T A G C T A G C A T G G T A C C A T G C A T C G A A C G A T C C T A G G T A G C T A C C T A C G T A C C A T C C T T G G A A G G A A G G T A G C T A C C T T G C A T G C A A C C A T G C A T C C T T C C A T G G T A G G A A G C A A C G T T C G T A C G A A C G T T G C T T C G T A C G T A C G T T G C T A G C A A C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C T A G C A A G G A A G C T T C C A T C G T T C C T T G C T A C C T A C G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C G A A G C T T G C T A C G T T G G T A G G T T C C T T C C A A G C T A C C T A G C T T G C T A G G A A C C T A G C T A C C A A C C T A G C A +A G C T T G G A T G C T A G C T A C G A A G C T A G G T T G G T A C C A A G G A T C C T T G C T T G G A A C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G T T C C T T G C T A C C A T G C T A C C A A C G A A G C T T C G A T C G A T G C A A C C T A C G A T G G T A G C T T G C A T C C T A G C A T G C A T G G T T C C T T C G A A G C T A C G A A G C T T G G T A G C A T G G A T G C A A G G A T G C A A G C T A C G A A C G T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A C G A A G G T A C C A T G G A T G G T A G G T A G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C C T A C G T A C C A A G C A A G G T A C G T A C G A T G C T A G C T A C G T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G A T C G A A C C T A C C T A G G T T C G A T C C T A C C A T G G T A C C A T G C A A C G T T G C A T C C A A G G T A G C T T C C A A G G T A G C T T G G A A C C T A G G A A G C T T C G T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T C G A T G G T T G C A T C G A A G G T T G G T T C C T T C C T T C G T A C C A A G C A T G G A A G G A A C C A A G C T A G C A A G C T A C C T A C C A A G G T T G G A A G G A A G G T T C C T T G G T T G C A T G G A T C C T A C C T A G G T A C G T A G C T T G C A T G C A T G C T A C C A T C C T T C C A T G C A A G C A T G G T A G C A T C G A T C G A T G C A T C G A A G C A A C C T T G G T A G C T T C C A T G C A T C G T A C G A A C C A A G C A T G G A A G G T A G C T T G C T A C G A A C C T T C C T A C C A A G G T A G G T A G G T T G C T T G C A A G C T T G C A T C G A A G C T A G C A T G G T A C G A T G G T A G G T A G C A A C C A T G C T A G G A A G G A A C G T A C G A T G C T T C G A A G C T T C G T A G G T T C G A A C G A A C C A A G G A T G C T T C C T T C C T T C C T A G G T T G G T A G G A A C C A A G G T T C C T A G C T A C G A A C G T A G G A T C G T T C G A A C C T T C G T A C C T A C G A A G G T T G C T T G C T A C G T A C C A T G G T A G C T A G G T A C G T T C G A T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C A A G G T T G C T T C C A T C G A T G G A A G G A A G C T A G C A A C C T T G G T A G C A A C C A A C G T T C C T T G G T T G G T A G C A A G C A A G G T T C G A T C G T A C C T T C C T T G C A A C G T A G G T A G C T A G G T T G C A A G C T T G C T T C C T T G C T T C G T T G G A A C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C C T T G C A A C C A A C C A A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C A T G C T T G G A A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G C T A C C T A G C A T G G T A C C T T C C T A G C T A G C A A C G T A C C T CGU_MN100 # subpop. label: 7 (internally 7) -1 1 2 2 1 2 1 1 1 2 2 2 2 2 1 1 1 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 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T C C T T G C A A G C A T G G A A C G A T G G A A G C T A G C A T C C A A G C A A C C T A C C T T C C T T C C A T C G T A C C T T C C A T G G A A G C A T G G A A G G T T C C A A G C T A C G A T C C A A C C T T G G A A G G T A C C A T C C A A C C T A C C A A G C T A C C A A G G A A G C A T C C T T G G A T C G A A G C T A G G T A C G A A C C A T G C T T C G A A G C T A G G T A C C A T G C T T C G A T C C T A C G A A C G T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G A A C G T T C C T A C C A A G C T A C C T A C C A T G G T T G C T A G G A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T A G C T A C C A T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T T C G A A C C T A G C A T G C A A G G A A C C T A G C A A C C T T C C A A C C A T G C A A G G T T G C A T C G A A G G A A G C T T G C T T C G A T C G T A C G T T C G T T C C A A G C A T C C T A C C T A G G T T C G T T G G T A G C T A C C T A G G T T C G T T C G T A C C T A G C T T C G T A G C A T G C A A G G A A C G A A C C A T C G A A G C A A C C T A C C T A C G A A C C A T C C A T G C A T G C T A C C T A C G A A G G A T C G A A C C A T G C T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C T A G C T A G C A A C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T T G C T A G C T T G C T A G C T A G G A T C C A A C G T T C C T T G C T A C G A A G G A A G C A A C C T A C C T A C C T T C C T T G C A T G G T A G C A T G C A T G G T T G G T T G G T A G C A T C G T A C C T A G C T A C C A T C C T T C G A T G C A A G C T T C C T T G G T T G C T T C C A T C C T A G C A A G G A T G C A T C C A T G G A T G C T T C C A T C G T T C G T A G G T A G C A A C C A T G G A A G G A A C C A A G G A A G G A T G C A A G C A A C G T A G G T T C C T A G G T T G G T T G G T A C C T T G C T A G C A A C C A A G G T T G C A A C G A A C G T T G G A T G C A A C G T T G G T A C C T T G G T T C C T A G G A A C G A A G C T T C G T A G G T A G C A A G C A T G G T A G G T A C C A T G C T T C C T A G G A A G C T A C G T A G C A A C C T T G C T A C G A A G C T T G C A T G G T T G G T T C G T T C G A T G G A A G G A T G C A T C G T T G G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T C C A T G C A A C G T T C C A T G C T T G G T A C C A A C G A T G G T A C G A T G G A A G C T T G G A A G C T A G C A A C C T T G G T A C C A T C G T T C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C C T T C G T A C C A A G G A T G C A A G G A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T G C T A C C T A G G A A G C T A C G T A C C T T G G A T C G T T G G T A G G T T C C T T G C A T G C A T G C A T C G T A G G T T C C T T C C A A G G T A G G T T G C A A G C A T C G A T G G A T G C A T C C A A C C A A G C T A G C A A G G T T C G A A G C T T C G A T C G A T C G A T G C T T G C T A G G T A C C A A C C T A C G A T C C T A C C T T G C A A G G T A G C A T G C T T C C A T G C A A C C T A G C A T C G A A G C A T C C A T G C A A C G A T C G A T C C T A G C A A G C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T G G A T C G A T C C A A C C A A G G A A C C T T G C T A G G A T G G T T G C T A G G T A G C T A G G T A C G A T C G T A C G T A C C A T G C T A C C T T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A G G A T C C T T C C A A G C T T C C T A G C A T G G T T C G T T C C A A G C T A C G T T G G T T C G A A C C T A G G T A C C A T G C T A G C T A G C A A C C A A G C T T C C A T C G T T G G T A G C T A C G A T G G A T G C A T C C A A G C A T G G A T G G T A C C A T G C T T G C T A G G T A G C T T C C T A C G T A G C T T G G T A C C T A C C T A G C T A C G T A G G T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN101 # subpop. label: 7 (internally 7) -2 1 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 1 2 1 1 1 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 1 1 2 1 1 1 2 1 2 2 1 2 1 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 1 2 1 2 1 1 2 1 1 1 1 1 1 1 1 1 2 2 1 2 1 2 1 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 1 1 2 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 2 1 2 1 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 2 1 1 1 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 1 1 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 1 1 2 1 2 1 2 2 2 2 2 2 2 1 1 1 2 2 2 2 1 1 2 2 2 2 2 1 2 1 1 2 2 1 1 2 2 2 2 1 1 2 1 2 1 2 1 2 2 1 1 2 2 1 1 1 2 1 2 1 1 2 1 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 1 2 1 2 1 2 1 2 2 1 1 1 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2 1 1 2 2 1 2 1 2 1 2 1 1 2 +A C C T A C G T A C G T T G C T A C C T T G C T A G G A A C G A A C C A A G G A T C C T T G C A T G G A A C G A A C C T T G G T A G C T A C C A T G C T A G C T T G G T T C C A T C G A T C G A A G G T T G G T A G C A T C C T A C G T A G G T A G C A T G G A T C G A T G C T A G C T T C C A A G C T T G G T T C G A T C C T A G C A A G G A T C C T T C C A T G G A A G C T A C G A A G C T T G G T A G C T T G C A A G C A A G G T T G C T A G C T A C G A T C G T A C C T A G C T A G C T A C G T T G G T A G C T A G G A T G C T A C G T A G C T T G G A A G G A A G C T T C C A A C C A A G G A A G G A T G G T T C C A T G C A A C C A T G C A A C C T A G G T T G G T T G C A T C G A A C C T A G G A A G C A T G C T A C G T T G G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G C A A C G T A G C T T C C T A G G T A G C A T C G T A C G T A C C T T G G T A C C T A G G T T G C T A G C A A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T T C C A A G C A T G C A T G G T A C G A A G C T A G G T T C G A T G C T A G G A T C G T T G C T A C G A A G G T A G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G G T T G G T T G C A A C C T A G C A T C G A A G C T A G C A T C C A A C C A A G C T A G C A T C C T T C G T T C G T T C C T A C G T A G G A A G C T T G C T A G G T A C C A A C C T A C G A T C C T A C C A A C C A A G G T A G C A T G C T T C C A T G C A A C C T A G C A A G G A A G C A T C C A T G G A T C G A A G C T T C C T A C G T A G C A T C C T A C G A A C G A A G C T A C G T T G C T T C G A A C C T T C G A A C G T T G C T A G G A T C C T A G G A T C C T A C C T A G C A T C G T A G G A A C G T A G G A T G C A A G C T T C G T A C G A T G G T A G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C C T T G G T T G C T T C G A A C G T T G G A T G C A T G C A T G G T A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G C T A C C T A C C T A C C T A G C T A C C A A C G T T G G T T G C A A G G T A G G A A C C A T G G A T G C T A G G A T G G A T C C T T C C A A C G T T G G T A C C T A G G T T G G A T G C T T G C T A C G T T G C T T C G A A C C T A G G T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C G T A G C T A G C T A C C T A C C A T C C A T C C A T C C A T G C T T C C A A G C A T G C T A G C T A C G T A G G T A C C A A C G A T G C T T G G A A G C T T C C T A G C A A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G G A A C G T A G C T A C C A A G C A A C C T A G C T A G G T A G C A A C G T +A C C T A G G T A C G T T G C T A G C A T G C T A G C A A G C T A C G A A G G T T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A C C T T G G T A G C A T G C T T G G T T C G T T G C T T C C A T C C A A C C A A C G T A G C A T G C A A C C T T C C T T C C T T C C A A G G T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G A A G C T A G G A T C G T T C C A A G C A A G C T A G C A A G G A T G C A A G C T A G C A A C C T T C C A A G C A A C G T A G G T T G G T A G G T T G G T A G G T A G G A A G C A T G G A A C G A A G G T T G C A A C G A T G C T A G G A A G G T T G C T T G C A A C C A T G C A A C C A T C G T A G G T A C G A A C C T A C G A T G C A A G C A A G G T A C G T A C G A T C C A T C G T A C C T T G G T T C G A A G G T T C G T A C G T T C G T T C C T T G C A T G C A A C C T T C G T A C C A A C C A A C C A A G G A A G C A T C G A T G G T A G C T A G G T T G G A A G C T A C C A T G G T A C C A T G C A A C G T T C C A T G C T T G G T A C C T T G G A A G G T A C C T T G G T T G C T A G C T A C G T A C C A T G G A T C C A A G G A A G C T T C G A T G G T T C C T T G C T T C G T T G C T A C C A A C C T A G C T T G G T T C G T A G G T A C G A A G C T T C G A A C C A A C G A A G G A A C C A A G C T A C C T A G G A T G C T T G C T A G G A A G G T A G C A A C G T A G G A T G G A T C C T T G C T A G G T A C G T A G C T T G G A T G C T T G G A T G C T T C C T A C G T T C G A A C C A T G G T A C C A T G C A A G G A T C G A T C C A A G C A A C C T A C C T A G G T T C G A A G C A T C G A T C C A T C C A T C C A T G G A T G C T T C C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A C C A A C C A T C C A A G C T A C C A T G G A A G C A T C G T T C C A A C G A T C G A T C C T T G G T A G C A A G C T A C G A A G G A A G G T A C G T T G G T T C G A T C C T A C G A A C G A A C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G A A C G T A G G T A C C T A G G T A C C T A C G A T G G A T G G T A G G A T G C T T C G A A C C T T C G T T G C T A G C T A G G A T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C A A G G T T G G T T C G A A C C T A G G A A G C T T G C T A G C A A G C A A C C T A G C A T C C A T G C A T G G T T G G A T G G T A G G A A G C A A G C A T G G T A G G A T G G A T C C T T G C A A C G T T G C A A G C T A G G T T G C A A G C T T G G T T C C T T G G T T C G T T C C T T G G T T G C A T C G T A G C T A C G A A G G T T C G T T C C T T C G T T G C T T C C T A C C T A G C A T C G A T C G A A G C A T G G T T C C T A G G A A G G T T C G A A C G A T G C T T G C T A G C A A G C A T G G T A G G A T C G A T C C A A C C A T C G T T G C T T C C T T G C A A G C T T G C T T C C T A G C T A C C T A G G T A C G A T G C A T G C T A G C A T G C A A C C A A C G T CGU_MN102 # subpop. label: 7 (internally 7) -1 2 1 2 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 2 1 1 2 2 1 2 2 2 1 2 1 2 1 1 2 2 1 2 2 1 1 2 1 2 1 1 1 2 1 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 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A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C T T C G T A G C A A G G A T G C T T G C T T C C T T C C T A G G T A C G T A G G T A G C A A G G T T C G T A C G A T G G T T C G T A G G T A G C A A C G A T C G A T C G T A C C T A G G A A G G T A G G T A C G T A G G A T G C A T G G T A G C T T G G T A C G T T C G T T G C T A G G A A G C T A C C A T G C A T C C T A C G T A C C T T G C T T G C A A G G A T G C T T C C A T C C T T C G T A G G A A G C T A G C A A G C T A C C T T G G A T C G T T G C A A G G T T G G T T C G A A G G A T G C T A G G T A C C A T C G A A G C T T C C T T C C T A G G T T C G A T G C A T G C T A G G A T G C T T C G T T C C T T G C T A G C T T C C T A G G T T G C A T G C A A G C A T G C A A G G A A C G A A C C T T C G T A G C T A C C T A C C A A C G T A C C A T C C A T G C T T G G A T G G T A G C A T G C T A G C T A C G T A G C T T G C T A C C T T G C T A G C A A C C A 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C T A G G T A G G A T G C T T C C T T C G T T C C T T C G T A G G T T G C T T C C A T C C T A G C A A G G A T C C A T C G A A G C A A G C T A C G A A G C T T C G T T G C T T G C A A G C A A C G T T G C A A G C T A G C A A C C T T G C A A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T A C G T A C G T A G G T A C C A A C G A T G C T A C G A A G C T T G G T T G C A A G C A T G C T A C G A A C G T A G G T T G C T A C G A A G C T A G C A A C C T A G G A T C G A A C G A T C C A A C G T A C C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C C A A G G T A C G A T G G T A G G T A G G A A G G A A C C A A G G T A G G T A C C A T C G A T C C A A C C T A C G T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T T C C T A G G T A C C T T C C T T C C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G T A C G A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G A A C C A A G C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G T T C C T A G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T A G G T A C G A A C C A T G C T T C G A A G C T A G G T A C G T T G C T T C G A T C C T A G G A A G G T A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T A G C A A C C A A G C T A G C A T G G A T C G T A G G A T G C T T C G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T A G C T T G G T A C G T T G G A T G C T T G C T A G C T A C C A T G C A T G G T A C C A A C C T T G C T T G C A A G G A T C G T A C C A T C C T T G G A A C G A A G C T T C C A A G C T T G C T T G C A A C C A T G C A A G G T A G C T T G G T A C G A T G C A A G C A T G G A T C G A A G G A T C C T T C C T A G C A T G C T A C C T A G C A T C G T T G C A T G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G A A G C T A G G A A G G A A G C T T C C A T C G T T G C A A C C A A C G T A C G T T C C A T C C A T G C A T C G A T C G T A G C A T G G A T C G T A C G A A G G T A C C T A G C A A G C A T G G T A G G A T C G A T C C A A C C A T C C T T G C T T G G T T G C A A G C T T G C T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A C G T A C C T T G C T A C C T T C C A A G G A A G C T A C G A A G G T A G G A A G C A A C G A T G G A T C C T A C C T A G G A A C C T A G C A A C C T T G G A T C C A T C C T T C G A A G C T T G G T A C G A T C C A T C G A A G C T A G C A T C C T T C G T T G C T A G C T T C C T T G C T T G C T T C C A T C C T A G C A A G G A T G G T T C C T T G G T A G C T A C G A A G C T T C G T A C C A A G C A T G G A A G G T A G C T A C G T T C G A A G C T A C C A A G C A A C G T A G G A T C C T A G G T A G G T T G G T A C G T A G C T T G G A A C G A A G G T T C C A A C G A A G G T T G G A T G C T T C C T T G C A T C C A T G C T A C C A A C G T T G G T A C C T A C C T A C C T A C C A A C G T A G G T A G G T A C G A T G C T A C C T A C C T T C C A A G G A T C C A A C C A T G G T T C G T T C C A T C G T T C G T T G C T A C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G A A G C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A G C A T G G A T C C T A C C T A G C T T G C T A G G A A G C T A C C T T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T A C G A A C G T A G C A A G C T T G C A T G G T T C C T A G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A T C G A T C C T A C G T A C G A A C G T A C G A A C C A A G G A T G C T T C C T T G C A T C C A T G G T A C G T A G G T A G C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A G G A T C C A A C C A A G G A A C C T T G C T A C G T T G G T T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C T T G G A A C C T T C G A T C C T A C C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G T A G C A A G G A A C C A A G C T T G G T A G C A A C C A T C G T T C C T T G G T T G G T A C G A T G C A A C C T T G G T A G G A A G C T T C C T T C C T A G G T A C C T A C C T A G G T T G G T T G C A A G C T A C C T A G C T T C G T T C C T T G G T T G C A T C G A A G C T A G G A A G G A A C C T A C G A T C G T T G G T A G C T A C G A A G G A T C C A T C G A T C C T A G G A T G G T A C C A T G G T A G C T A C G A A G C T T C C A A C G A A G C T T C G A A G C T T C C T T C C A A C C A T C G T T G C T T C C T T C C A A G G T T G C T T C C T A G C A A C C T A G G T A C C A A C C A A C C T A G G T A G G T A G C A A C G T CGU_MN106 # subpop. label: 7 (internally 7) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 1 2 1 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 1 1 1 1 1 1 1 2 1 1 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 2 1 2 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 2 1 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 1 1 2 1 1 1 1 1 1 1 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 1 1 1 1 1 2 2 1 1 1 1 2 1 2 1 1 1 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 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T C C A T C G T T C G T T G C T A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T G C A T C C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C G T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A G C A T C G T T G G T A G G A A G G A T G G A T G C A A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A G G T T G C A T G C A T C G T T G G T T G C A A G G A T G G A T C C A T G C A A G G A A G C A T G C A A C C T A C C T T C C T T G C T T C C A T C C A A C G T A C G T A G C A A G C A T G G A A G G T A C C A A C C T A C G A A C G T A C C A A G C T A G G T A C C A A G C T T G C A T G C A A G C T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C G A A G G A T C G T A C G A 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A G G T A C C T T C C T A G C T A G C A A C G T A C C T +A C C T A C G T A C C T T C C T A C C T T G C T A G C T A C C T A C C A A G G T T C C T T G C A T G G A A C G A A G C T A G G T A G C A A C C T T C C T T G C A T G C T A G C A T C G A T G G T T G G T T G C A A G C A T C G T A C C A A G G A A G C T T G G A A C G A T G C T A G C A A C G A A G G T T G C T T C C A T C C T A G C A A G G A T C C T T G C A T C G T T C C T A G C A T C G A T C G T A G C A A G G A T C C A A G G T T G C T A C C T A C C A A G C T A C C T T G C T T G C T A C G T T G G T A G G T T G G T A G G T A C C A T G C T A C G A A C G A A G C T T C C A A C G A A G C T A G G A T G C T T C C T T G C A A G C A T G C T A C C A A C G T T G G T A C G T A C G A A C C T A G G A A G C T A G G A A C G T A C G A T G C A A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G C T T C G T T C C A A C C T T G G T A C C T T G G A A G C T A G C T A C C A A C C T A G G A A C G T A G C A A G G A T C C A T G G A A G C T A C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G C A A C C A A C G A A C C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G G A A G G A A G C T T G C T A C C A T C C T A C G T T G G T A G G A T G G A A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T A G G T T C G A T C G A A C G A A C G A T C C A T G C A T G G A A G G T A G C A T G C T T C G A T G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G C A A C G A A G G T T C C T A C G T A G C A A C C T A C G T T C G A A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A C C T A C C A A G C T A C C T A C C A T G C A T G G T A G G A T G C T A G G A A C C T T C G T T G C T A C G T A G G T T G C T T G G T A C G A T G C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C C A A C C T T G C T T G C A A G G T A C G T A C C A T C C T T C G A A G C A A G C T A G C T A G C T A C C T T G C A A C C A T G C A A G G T T G C A A G G T A G G A A C C A A C C T T C G T A G G A A C G T A C C T T C C A A G C A T C C T A C C T A G C T T C G A T C C A T G C T A C C T T G C T A G G T T C C T A G G T A C G A T G G T A G C T A G G A A G C T A G C T A C C A T C G A A G C T T C C T A C G T A C G A T C C A T C G A T G G A T C G T T G C T A G C A T G G A T G C T A C G A A G G T T G C A A C G A T G C T T G G A A G C T A C C T A G C T A C C T A G G T A G C A A C G T T G C A A G C T T G G T T G C T T G C A T C C T A G C T A C C T A G G T A C C T A G G T A G G A A C C T A G C A CGU_MN107 # subpop. label: 7 (internally 7) -2 1 2 2 2 2 1 2 1 1 1 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 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G T T G C T A C G T A G C T T G G A A C C A A G C T T C C T A C C A T G G T A G G A T G G T T G G T T G C A T C C A T G C A A C G A A C G T T G G T A C G A A C C A A G G T A C C A A C G T A G G A A G G T A C G A T G C A A C C T A G C T T C G T T C G A T C C A T C C T T G G T A C G T T G C T T G C T T G G T A G C T T C G T A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T A G C T T C C T T C C T A G C A A C C A T G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A T G C T A C G A T G G T A C C T T G C A T G G T T G G A A C G T A G G T T G C T A C C A A C G T A G G T A C C A A G C T T G C A T G G T A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G G A A C C A A G G T A G C A T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G G A A G C A A G C T T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C A A G C A T G C T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A A G C T A G C A A C C T A C G T A C C A A G G T A C C T T C C T A C C A T G C T A G C T A G C A T C G A A G C A T C C A T G G T A C G A T G C T A G G T A G C A A C C A T G C T A C G A A G C T A G G T A G G A T G C A T C G A T C C T T C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C A A G C A T C C A T G G T A C G T A G G T A G C A A C C A A G C T T G G A T C G A T C G T T C G T T G C A A G G A A C C T T C G T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T G G T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C C T T C C T A C G T T G C A T G G T T C G T T C G A T C G T T C G T A G C T T G C T T C C A A G C T A C C T T G C A A C C A T G C T T G G T T G G T T G G T A G G A A G C A A C C T T C G T A G C A A C C A T C C T T C C T A C G T T C G A T G C T A G G T T C G T T G G A A G C T A C C T A G C T A G G T T C G T A G G A A G G T A G C A A G C T A G C A A G G A A G C T A C C A T G C T A G C T A C C T A C C T A C C A T C G A A G G A T C C T A G G T T G C A T C G A A G G A T C G T A C C T T G C T T G C T A C G A T G C T A G G A A G G A A C C T A G C A A C C A T C G T T G C T T G G T T G C A A G C T T G C T T C C A A G G A T C G A T G C T A G C A A G C A T C G A A G C T A C C A A G G T A C C T CGU_MN108 # subpop. label: 7 (internally 7) -1 2 2 1 2 1 1 2 2 1 2 2 2 2 1 1 1 2 1 2 2 1 1 1 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 2 1 1 2 2 1 1 2 2 1 2 1 1 2 1 1 1 1 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 2 2 2 2 1 1 2 1 2 2 1 2 1 1 1 1 1 1 2 1 1 2 1 1 2 1 2 1 2 2 1 2 1 1 2 1 2 2 1 1 2 2 2 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 2 2 1 2 2 2 2 1 1 1 1 2 2 1 2 1 2 2 2 2 1 2 1 1 1 2 1 2 2 2 1 2 2 1 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 1 1 2 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 2 1 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 2 2 2 2 1 2 1 1 1 2 1 2 2 2 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 2 2 1 1 2 2 1 2 2 1 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T G G A T G C A T C C T T G C T A G G A A C G T T G G A T G C A T G C A T G G T A C C A A G C A T G G T A C C A A C C T A G G T A C C T A C C T A C G T A G C A T C C T T C G T A G G A A G C T A G C A A C C T T G G T A G C A T C C A A C G T T C C T T G G T T G G T A G G A A G G A T G C A T G G T A G G A A C C A T C C T T G C T A G G T T G C A T C C T A G C T T C G T T G G A A G C T A C G T A G C T T C G T T C C T T G G T T G C T T C G A A G C T A G G A A G G A T G C T T C C T A C G T T G C T T C G T A C C T A G C A T C C A T C C A T G C T T G G A T G C T A G G A T G G A A C C T A C G T A G C T T G C T A C C T T G C T A G C A A C C A T C C T T C G T A C C A A C C T T C C A T C G T T G C A A G C T T G C T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A C C T A G G T A C G T T G C T A G C A T G C T A G C T A C G T A C C A A G G A T C C T T G C T T G G T T C G A T G C A T G G T A G C A T C G A T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T T C C T T G C T A C C A A C G A A G C T T G G A A C G T T G C A A C C T T C G T A C C T T G C T T G C A T C C T A G C A T G C A T G C T T C C T T G G T A G G A T C G A A G C T T C G T A G C T T G C A A G C T A G C T T G C T A C C T A G G A A C G T T C C T T G C T T G C T A G G T T G G T A C C A T G G T A G G T T C G T A G C A T G G A A C G A A G G T T G C A A C G A A G G T A G G T A C G A A C C T T G C A A C C A A G C T A C C A T C G T A C G T A G C T T C G T A G G T T G C A A C G T A G G A A C G T A C G A T G C T A C C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C C T A G G T A C C T T G G A A C C T A G G A A G G T T C G A A G G A A G G T A C C A T C G T A C G A T G G T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G G A T C C A A C C A A G G A A C C A A G G T T C C T A G C A T C G T T G C T A C G A A G G T A C C T T G G T T G G T T C G A T C C T A G C T A G G T A C C T A G C A A G C T A C C A T G C T A C C A T C C T T C C A T G C A A C C A T G C T T C C A T G C A T G G T T G C A T C C A A C C A A G C T T G C A T G G T A C G T A G C A A C G A A C G T A G G A A G C A T G G A A G G T A C C T T G C T T C G A A C G T A C G T T C C A A G G T A C G T A C C A A C C A T C C T A C C T A G C A A G G A A G C T A C C T T G C A A C C A A G C T A C C T A C G A A C C A T G C T T C G A A G C A A C G A A C C A T G C T T C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A T G G T T G C T A G G T T G C T T G G T A C G T T C G T A G C A T C G A T G C T A C C T T G C A T C C T A C C A A C C T T G C T T G C A A G G A T G C T T C C A T C C A T C G A A G G T A G G A A C C T A G C T A C C T T C C A A C C A T G C A A G G T T G G A T G G T A G G A T C C T A G C T T C G T A G G T A C G T T G C T T G C A A C G T T G G A A G C A A G G T T C G T T G C A A G C A A C G T T G C T A C G A A C C T A G G T A C G A T G C A A G C T T G C A A G G A A C C T T C C T T C G T T G C A A C G T A C C A A G C A T G G A T C G A T G C T T G G A T G C T A C C A T G G T A G C T A G G T A G G A A G C T A C C A T C C T T G G A A G C T T C C T A G C T A C C A A C C T T G C T A C G T T G G A A G G T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T C C T A G C T A G C A A C G T A C C T CGU_MN111 # subpop. label: 7 (internally 7) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 1 1 2 2 2 2 1 2 2 2 2 1 1 2 1 2 1 2 2 1 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 1 1 2 1 2 2 2 1 2 1 2 1 2 2 1 1 2 2 1 1 2 1 2 2 2 2 2 1 1 2 2 2 2 1 2 1 1 2 1 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 1 2 2 2 2 1 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C T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A C G A T C G T A G C A T G C A T G G T A C G A T G G T A G G T A C G T A C C A T C C T A C C T T C C T A G C T A G G T T G C T T G C A T C C T A C G A A G G T T G C A A C G A T C C A A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T G G T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T C G A T C G A A C C T T C C T A C G T T G C A T G G T T C G T T C C A T C G T T C G T A G G A A G C T A G C A A G G T T G G T A G C A T C C A A C G T T C C T T G G T T G G T A G G A A C C A T C G T T G G T A G G A A C G T T G C T T G C A A C G T T G G A A C C T A G C A T C C T T G G T T G C T A C G T A G C T A G G T T C G T A G G T A G C T T C G A A G C A T G C A A G G A A C C T A C C T T C G T T G C A A C G T A C C T A C C A T C C A T C C A T G C A T C G A T C G T A G 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C A T C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G C A A C C A A G G A A G C T A G C T A C C T T G G T A G C A A G G T A C G A T G G T A C C T T G C T T C G T T G C A A C G T A G G T T G G A A G C T T C G T A G G T T C C A A G C T T C G T T G C A A C G A A G G A A C C A A G C T A C C T A G C A T G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A G C T A G G T A C G T A G C A A G C T A C C A T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G C A A G C T T C C A T G C A A C C T A C G T T G C T T G G T T C C T T C G A A C G A A C G A T C C A T C C A T G G A T C C A A C C T T G G T A C G A T G G T A C G T A C C T A G C T A C G T T C C T A C G A T G C T A C C T A G C A T G C A A G C T T C C T T G C A A C G A A G C A T C C A A C C A A C C A T G C T A C G A A G C T A G G T A G G A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A C C T T C C T A C C T A C G A T C G T A G G T A G C A A C G A T C G A T G G A T G C T T G G T A C G T T G C T T G G A T G G A T G C A T G G T A G G A T G G T A C G T T G G A T G C T A G C A A C G T T C C T T G C A T C G T A G C A A C C T T G C T A G C T T G G A T G C T T C C A T C C T T G G A A G G A A G G A A C C A T G C T A C C T T G C A A C C A T G C T T G G T T G G A A G G T A G G A T G C T T G G A T G G A A G C A A C G T T G C T T C C T A C C T T C C T A C C T A G C A T C C T T G G A A G C T T C C T A G C T A G G T T C G T T C C T T G C T A G C A A G C A T G C T A G G A A G C T A C C A T G G T A C C A A G C T A C C T A C C A T C G A T C G A T C C T A C G T T G C A A G C A T G G A T C G T A C G A A G C T T C C A A G C A A G C A T G G A A C C A T G C T T C C T T C C A T C G T T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A C C A A C C T T C C T A G G T A G G T A G C A A C G T CGU_MN112 # subpop. label: 7 (internally 7) -2 1 2 2 1 2 1 1 1 2 2 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 2 2 2 2 2 2 1 1 2 2 1 2 1 2 1 2 1 1 2 2 1 2 1 2 1 1 1 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 2 1 2 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 1 2 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 1 2 1 1 1 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 1 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 1 1 2 2 1 2 1 1 2 2 2 2 2 1 1 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 1 2 1 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 1 1 2 1 1 2 2 1 1 2 2 2 1 2 1 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 1 1 2 2 2 2 1 1 1 2 1 1 2 1 1 1 2 2 1 2 1 1 2 1 2 1 1 1 2 2 1 2 1 2 1 1 1 2 2 1 2 1 1 2 1 2 1 2 2 1 2 1 1 2 2 2 2 1 1 1 2 1 1 2 1 2 2 2 2 2 2 2 1 1 1 1 2 2 1 1 1 2 1 1 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 1 1 2 2 1 1 1 2 2 2 2 1 2 1 1 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 1 1 1 1 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 2 1 1 1 1 2 2 1 1 2 2 2 1 2 1 2 2 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A G G A T G G T T C C T T G G T A G C T A C G A A G C T T C G T A C C A A G C A T G G T A G G T T G C T A C C T A G C A A C G T A C C T A G C T A G G A A G G T T G G T A G G T A G G T A G G T A C G A T G C T T G G A A C G A A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C G A A C G T A G G T A C G T A C C T A G G T A C C A A G C T A C C T T C G A A C G A T C C A A C C A A G C T T C G A A G G T A G C A A C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G T A C C A T G G T T C G A A G G A A C C T A G C T A G C A T C G A A G G T A C C T T G G T A C G T T C G A A G C A A G C A T G G A A G G T T G G A T C G T T C G A T G C A A G C T T C G T T C G T A G C A T G G T T G G A T C C T T G G T T C G T T C G T A C C A T G G T T G C A A G C A A C G A A C G A A C C A A G C T A C C T A G C A T G G T T G C T A G G A A C G T A G C A T C G T A G C A T G G A T C C T A C C T A G G T A C G T A G C A A G C T A G C T T G C A T G C A T C G T T G C A T G G T A G C A T G G T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T C C T T G C T T C G T T G C A T C G T A C G A A G C A A G C A T G G A A G G T A G C T T G C T A C G A A G C T T C C T A C C T A G G T A C G T T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A C C A T G C T A C C T T C C T A G G T A C C A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C C T A G G T A G C A A C C T A C C T A C C T A C G A T C G T A G G T A G C A A C G A T C G A T G G A T G C T T G G T A C G T T G C T T G G A T G G A T G C A T G G T A G G A T G G A A C G T T G G A T G C A T G C A A G G A A C C T T G G A T C G A A C G A T C C T A G G A A G C T A C C T A C G T A C C A T C C T T C G A A C G A A G G T A C C T A G C T T G C T T G C T A C C A T G C A A G G T T G C A T G G T A C G A T C C A T G G A A C G A A G G T A C G T T C C T T G C A A C G T T G G T A C C T A G C A T C C T T G G T A G C T T C C T A G C T A G G T T C G T T C C T A G C T A G C A A G C A T G C T A G G A T G G A A C C A T C G T A C C T A G C A A C C T A G C A T C C A A C G A T C C T A G G T T G C A A G C A T G G A T C G A A C G A A G G T A C C T A G C A A G C A T G G T A G C A A C C T T G C T T C C T A C G T A G C A A C G T T G C A A G C T T G G T T C C T A G C A A C G T A G C T A C C A A C C T T C C T A G G T A G G T A G C A A C G T CGU_MN113 # subpop. label: 7 (internally 7) -2 1 2 1 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 2 1 1 2 2 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 1 2 2 1 2 2 2 2 1 1 2 2 2 1 1 2 2 1 2 2 1 1 2 1 2 2 2 2 2 1 1 1 1 1 2 1 2 1 1 2 2 1 2 2 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 1 1 2 1 2 1 1 1 2 1 1 1 2 2 1 2 2 1 2 1 2 2 2 1 1 2 2 2 2 2 1 1 1 1 1 1 2 1 1 2 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 1 1 1 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 2 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C A T G G T A G G T A G G A A C G A A C C T T C C T A C G A T G C T T C G T A G C A T C G T A C G A T C G A T G G A A G C A T G G A A G G A T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G T T G G T A C C A T C C A T C G A T G C A A G C T A G C T A G C T A C C T T G G A A C C A T G C T T C C T T G G T T G G T A G G A T C C T A G G T T G G T A G G A T G G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C G A A G C A T C C A A C G A A G C A T C G T T G C A A G G A A G G A T C G A A C G A T G G T A C C T A G C A A G C A T G G T A G C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C C T A G G T A C G A T G C A T C C T A G C A T G C A A C C A A C G T CGU_MN114 # subpop. label: 7 (internally 7) 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A G C T A G C A A G C T T G C T A G C T A G C T A G G T T G G T A G G T A G G A A G G T A G C A T G C T A C G A A C G T A G C T A C C A A C G A A G G T T G G A T G C A A C G T T G G A A G C A T G C T A C G A A C G T T G C T A G C T T C G A A G G T A G G A A C C T A G G A T C G A A C G A T G C A T C C T A G G T T C C A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A T G G T A C C T T G G T A C C T A G G A A G C T A G C A A C C T T G G T A G C A A G C T T C G A T G G T A C G T T G C A T C G A A C C T A C G T T G G A T C C T T C C A T C C T T C G T A C C A A G C T T G C A A G C A A C G A A G G A A C C A A G G T T C C T T G C A T G G T T G G A A C C T A G G T T G G A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C C T T G G T T G C A A G C A T G G T A C C A T G C A A G G A A G C A T G C A A C C T A C C T T G G A A C C T T C G A T C G A A C G A A C C A A G C A T G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G A A C C T A G G T A C G T A G C T T G C T T C C A A C C T A G C A T C G A A G C T T G G T T C C A A C G A A G G T T C C T A C G A A C C A A G C T A C G A A G C T A G C T A C G A T G C A T C G A A C C T A C G T T G C T T G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T T G G T A G C A A G C T T C G T A G C A T G C A T C G T A G G A T G C A A G G A T C C T T C G T A C C T A G G A A G G T T G C T A C C T T G G T T G C T T C C T T G C T A G G T A C G T T C C T A G C T A G C A A G G A A C C T T C G A T C G A A C G A T C C T A C G T A G C T A C G T A C G T A C C A T C C A T C G A A C G A A G C T A G C T T G C T T C C T T G G A A C G A T G C A T G C A A G G A A G G A A G G A A C C T A G C T T C G T A G G A T G G T T C C T T C C T A C G T A C C A A G C A T G G T T C G A T C C A T G C T A C C T A G C T A G G T T C C T T G G T A C G T T C G A A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A G C T T C G A T C G A A G C A T C G A T G C A A G G A A G G A T C C A A C G A A G C T T G C T A C G A T G C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C A A G C A T C C T T G C A T G G A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +A C C T A C G T A C G T T G C T A G G A T G C T A G G T A C G A T C C A A G G T T C C T T G C T T G C A A C G A T C C T T G G T A G C T A C C T T G C T T G C T T G G T A G C A T G C A T G G T A G G T A G G A A G G T T G C T A C C T A G G T A C C A T G C A A C C T T G C A A G C T T C C T A G G T T G C T A G C A T C G T A G C A A G C A T C C T T C C A T G G A T G C T A C G A A G C T T C G T T G G T A G G A A C C T A G G T T G C T A C C T T C C A A G C T T G G A A C G T A C G T A G G T T G C T A G C T A G G T T G G T T C C T A G G A T G G A A C G A A G G T T C C A A C C A A G G T A G G T T G C A A G G T T G C A A G C A T G C T A C G A A C G T A G G T A G G A A C C T A G G T A C C A A C G T A G G A A C G T A C G A T G C T A G C T A C C T T C C A A G G A T C C A T C C T T C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G C A A G G A T G G T A G G T A C G A A C C A T C C T A G G A A G G A A G C T A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G G T A G G T T G G A A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G A T C C A T G G A A G C T A C C T A G C T A C C A T G G A T C G T A G C A T C G A A G G T T G G T T C C T T C G T A G G T T C C A A G C T T C G T T G G A T C C A A G C A A G C A A G C T A C C T A G C A T G G T T C C T A C G A A G G T A G C T T G G T T G C T T G G A T C C T A C G T A G G T A C G T A C C T T G G A A C C A T G G T T G C A T C C T T G G A T G G T T G G A A G C A A C C A T C G A T C G A T G C A T C G A A G C A A G C T T C C T T G C T T C C A T C C A A C G A A C C A T C G A T G G A T G G A A G G T A G C T T G C T A G G A T G G A A C C T T C C T A G G A A C G T A G G T T G C T T G C T A G C T A G C A T C G A A G C T A G C A T G G T T C C A A G G T A C C T T G G T A G C A A G C T A C G A A C C A A G C T A C G T T G C T T G C A A C C T A C G A T G G T T G C T A C G A T C C T T C C A A C G T T C C T T C G A A C C A T G G A A G G T T G G T A C G T A G C T A G C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T C G A A G C T A C G T A G C T T G C T T G C T A C G T T G C T A C C T A G C T T G G T A C G T A C G T A G C T A C C A T C C T T C C T T G C A T C G T A C C A A G C T A C G T T G C A A G G T T G C T A C C A T C C T T C G A A G C A A G C T T C C A A G C T A C C T A G G A A C C A T G C A A G C A T G C A T G G T A G G A T G C T A G G T T G G A A G G A A G G T T C C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C G T A C C T T C C A T C C A T G C A T C G A T C G T A G G A T G G T T C C T A C G A A G C T T G C T A C C A T G C T A G G A A G C T A C C T T C C T A C C T A C G T A G C A A C C T T C C T A G C T T G C T T C C T A G C A T C G T A G C T A C C T A G C T T C G A A G C T A C C A A G G T A C C T CGU_MN117 # subpop. label: 7 (internally 7) -2 2 1 1 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 1 1 2 1 2 1 2 2 2 2 2 1 1 2 2 1 1 1 2 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 2 2 1 2 1 1 1 1 2 2 2 2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 2 2 1 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 1 1 1 1 1 2 2 1 1 2 2 2 2 2 1 2 1 1 1 1 1 1 1 1 2 2 2 2 1 2 1 2 1 2 1 2 1 2 1 1 2 1 2 2 1 2 1 2 2 2 2 2 1 2 1 1 2 1 2 2 2 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 1 2 2 1 2 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 2 2 2 2 2 1 2 2 2 1 2 1 1 2 1 2 2 2 1 2 1 2 1 2 1 1 2 2 1 2 2 1 1 1 2 1 1 2 2 1 2 1 1 1 2 2 1 2 2 2 2 2 2 2 1 1 1 1 1 1 2 1 1 1 1 2 2 1 2 2 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1 2 +A G G A A C G T A C C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T G C T T G C T A G G T T C G A T C C A A C C T A G C A T G C A T C C T A C C T T G C T A G C T T G C T T G G A T C C T A G C T A C C A T C C T A C G T A G G A A G C A T G C A A C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C A T C G A A G G A A G C T A C C A T C G A T C G T A G C A A C C A A C C A A C G T T G C A A C C T A G C A A C G T T G C T A G C T A G G T A G C T T G G T A G C T A G G A A G G T A G C A T G C T A C G A A C G T A G C T A C C T A C C A T G G T A G G T T G G T T C C T T G C A T C C A T G C A A C G A A G G T A G C T A G G A T C G A A C G A T G C A A G C A T G G A A C G A A C G A T C C A A C G T A G G T T C G A A G G A T C C T T C G T T G G T T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A T C G A A G G A T C G A T G G T A G C A T C C A A G G T A C G T T G C A A C C T A G G T T G C T T C G T T G G A T C C A A G G A A G C T T C G A T G G T A C G T T G C T T C G T T G C A A C G T A G G T T G G A A G C T T C C T T G G T A C C A A G C T A G G A A G C T T C C T A G G A A G C A A G G T T C C T A G C A A G G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T A G C T A G G T A C G T A G C A A G C T A G C A T G C T T C C T T C C T A C G T T C G A A C G A A G C T A C G A T G G A A G G A T C G A T G C T T C C T T G C T T G G T A G C T T C G A A G C A A G G T A C C A A C C A A G C T A G C A T G C T T C C T T G C T A C G A A C C T A C G T A G G T T C C T T C C A T G G T T G C T T G C T A C G A T G C T T C C A A G C T T C C A T G G T A C G A T G C T A G G T A G G T T G C A T G C T A C G T T C G A A G G T A G G A T G C A T C G A T C C T T C G A A C G T T G C A T C G A A C C A A G G A A C G T A C C A A G C A T C C A T G G A A G C T A G G T A C C T A G C A A G C T A C C T A C G A T C G T T C G T T G C A A G G A A C G A T C G T A C C T A G G A A G G A A G C T A C G T A C G T A C C A T G G T T G C T A G G T A C G T T G G A T G C T A G C A T G C A A C C T T G C A T G G T T G C T A C C T T G C T T G C A A C C T A C G T A C C A T C C T T C G A T G G A A G G A A C C T A G G T T C C T T G C A A C C A T G C A T G G T T G G T T C G T A G G A T G C T T G G A T C G T T C G T A C C T T C C T T G C A A G G T T G G T A G G T T G C T T G C A A G C T T C G T T C C T A C C T T G C T T C C T T G C T A C G T T G C A A G C T A G C A A G G A T G G A A C C A T C G T A G C T A C C T A C C T A G G A T C G A T C G A A G C A T G C A T G C T A G G A A G G A T C G A A C G A T G C T T C C A A C G A T G C T A G G A A C C A T C C T A G G T A C C A A G G T T G C T A C G T T G C A A G C T T G C T T C C T A C C A A C G T A G C T A C C A A G C A T G C A T G G T A G G A A G C T A C G T +A C C T A G G A T G G T T C C T A C C T A G C A A G G A A C G T A G G A A G G T T G C T T G C T T G G A A G G A A C C T T G G T A G C A T G C T T G C A A C C T T G C T A G C A T C C T T G G T A G G T T G G T A G C A T C G T A C C T A C G A T G G A T G G A T C C A T G G A A C C T T C G T T G G T T G G T T C C A T C C T A G C A A G G A A C C A T C C T T G G T A G C T A G C A T C G T T C G T A G C A T G C A A G C A A G G A T G C A A C C T A G C A A C G T A C C T T G C T T G C T A C G T T C C T A G C T T C C A T G C T A G G T A G C T T C C A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A C C A T G C T A C G A A C G T A G G T A C G A A C G A A C C T A G G A A C G T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C T T C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T A G G A A G C A A G G A T G C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A C C A T G G T T C G A A G G A A C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G G A A G C T A G C T A C C T T G G T A G C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A G C A A G C T A C C T T G C A T G G T T C C T A C G A A G G A A G C T T G G T A G G T T C C A T C C T A G C T A G G T A C G T A G G A A G C T A G C A T C C T A C G A T C C T T G G T T G G T T G G T T G C A A G C T A C G A A G G A A C C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A A C G T A G C A A G C A T C C A A G C A A C C T T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T G C T T G G A T G G A T G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G T A C C T A C G T A C G A A C G A A C G A A C C T A G G A T C C T A C C A T G C T T C C A T G G T A C G T A G G T A G C A A C C A A G C T T G G A T C C A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A C G A T G C T A G C T T G G T T G C T A G G T T G C T A G G A A C G T T C C T A C C T A G C A T G G A A C C T T C G A T C G A A C G A T G C T A C G T A G C A A G G T T C G T T C G A T C G T T C G T A G C T T G C T T C C A T C G T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A C G A T G C A A C G T A C G A A G G T A C G A T C C T T C C T A G G T A C C T A C C T A G C T T C C T T G G T A G C T A C C T A G C T A G G T T C G T A C C T A G C T T G G T A G C T A G G A A G G A A G G T T C C A T C G T A C C A A G C A A C C T A G C A T C C A A C G A A G C T T G G T T G C A A G G A A G G A T C G A A C G A T G C T T C C A A C G A T G C T A G G A A C C A T C C T A G G T A C C A A G G T A C C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C A A C C A A C G T T C C T A G C T A G C A A G C A A C G T CGU_MN118 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 2 2 2 2 2 2 2 1 2 2 1 2 1 2 2 2 1 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 1 1 2 1 1 1 1 2 2 1 1 1 1 1 2 2 2 1 1 2 2 1 1 1 1 2 2 1 1 1 2 2 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A C C A A G G T A G G T A G G T A G C A A C G T A C G A A G G A A G C T A C G T T G C T T G C A A C C T A C G A A G G T T G C T A C G A A C C T A G G A T G C T T C C T T C C T T C G T A G G A A C G T A G G T A C G A T G C T A C G T A C G A T G C A T C G T A G G T A G C A T G G A T C C T A C G A T C C T A G G A A C G A T G C T T G C A A C G T A C C A T G G T A G G A T G G T A C G A A C C T A C G T A G C T A C C T T C C A T G C A T C G T A C C T T G C T A C C T T G C A T C G T T G C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G G A T G G A A G G A A G C A T G G T T G G A T C G T T G G T T C C T T C G T A C G T T C G A A C C T A G C A A G G A T G G A A G C A A G G A A G G A A G C T T C C T A G C A A C C T A G G T A G C T A G C A A G G A A G C T T C C A T C G T T G C T T C C T A C C T A C G A T C C A T C G A A G C A T G G T T C C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A T G C T T G G A A G C T A C C T A G C T A C C A A C C T A G C T T G G T T G G A A G C T T G C T T C G T A G C A T C G T A G C T A G C T A G C A A G C A A G C T A G C A A C C T A G C T CGU_MN119 # subpop. label: 7 (internally 7) -2 1 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 1 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 2 1 2 2 2 1 2 1 1 1 1 2 2 2 2 2 1 2 2 2 1 1 1 1 2 2 1 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 1 1 2 2 1 1 2 2 2 2 2 1 2 1 1 1 1 1 1 1 1 2 2 2 2 1 2 1 2 1 2 1 2 1 2 1 1 2 1 2 2 1 2 1 2 2 2 2 2 1 2 1 1 2 1 2 2 2 2 2 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 1 2 1 1 2 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 1 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 2 2 2 2 2 2 1 1 1 1 1 1 2 2 1 2 2 1 2 1 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 1 1 2 2 1 1 1 2 2 2 2 1 2 1 1 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 1 1 2 2 1 1 1 2 2 2 2 1 2 2 1 1 2 2 2 2 2 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G A A C G T T G C A A C C T T C G A A G G T T G C T A C C A T C C A A G C A A G G A A C C T T C C T T G G T A G C A A G C T A G G A T C G T A G C T T G C A A G C A A G G T T G C A A C C T A G C T A C G T T C C A A G C T A G C T A C G T T C C T A G C T T C C A T G C T A G G A T G C T T G G A A C G A A G C T T C C T A C C A T G G T T G G T T G C T T C C T T G C A A C C A T G C T A C C A A C G T A G G T T G C T T C G A A G C T A G G A A C G T A G G A A C G T A C G A T G C T A C G T T C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C C T A G C T T C C T A G G T A G C A T C G A A C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T T G G T A C C A A G C A T G G A T G C T T C C T A C G A A G C A A G G T T C C T A G C A T C G T T C C T A C G A A G G A A G C T T G G T T G G T T C C A T C C T A G G A A G G T A C C T A G G A A G C A T G C T T G G T A C C A T C C A T C C A T G G T A G G A A G G A A G C A T C G A A G C T A G C T T C G A A G C A A G C T T C C T T G C A A G G T T C G T T C C T A C G T T C C A T C C A T G G A T G C T A G C A A G G T T C G A A C G T A G G T A C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C A T C C T T G G T A C G A A G C T T C C T A C G T A G C A A G C T A G G A A G C T A G C T A G G T T G C T A C G A T C C T T C G A A G G T T G C A A G G A T C C T A G G A T C C T A G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A G C A T C G T T G G T A G G A T G C A A G G A T C C T T C G A A G C T A G G A A G G A T G C T A G G A T G G A A C C T A G G T T G C T T C G A A C C T T C C T A G G T A G C T A C C T T C C A T G C A T G G T A C C A A G C A A C G T T G C A T C G T A C C T T C C A T C C T T C G T T G G A A G G A A C C A T G C T A C C T T G C A A C C A T G C A A G G T T G G A T G C T T G C A A C C A T C G A T C G T T C G T A C G A T C C T A G C A A G G T A C G A T G C T T G C A A G G A T G C A A G C A A C C A A G C T A C G T T C C T A G C T T G C T T G C T A G C T T G G A A C G A A C C T T C C A T C G T A G C T T C C T T C C T A C C T T C G A T C G A T C C T A G C T T C G A A G C A T G G T A G C T A C G T T C C A T C C T A G C T T G C T T G C A A G G A A C C T A G C T A C C A A G C T T G C T T C G A A G C A A G C T T G C T T C C T A G C A A C C T A G G T T G C A A G C A A C C A T G C A A G C A A C C T A G C A +A G C T A G G T T C G T A G C T A C C T T G C A A G G A A C G T T C C A A G G T T G G T T G C A A C G A A G G A A C C A T G G T A G C A T G C T T C C A A C C T A G G T A G C A T C C A T G G A T C G A T C G T A C C A T C G T A C G T A G G A A G C A T G C T T C G A T G C A A C C T T C G T T G G T T G C T A G C A T C C T A G C A T C C A T C C T T C C A T G G A A G C T A C C A A G G A T C G T A G C T T G C A A G C A A G G A T G C T A G C T A G C A A C G T T C C T A G C T A C C T A G G T T C C T A G G A A G G A A G G T A C C T A G C A A G C A A C C T A G C T A C C A A C G A A G G T T G G A T G G T T G C A T G C T T C C A T G C A A C C A A G G T A C G A T G C T A C G T A G G T A C C A A C G T T C C A T C G T A C G A T G C A A G C T A C C A T C C A A G G A T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G T A C C A A C G T A C G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T A G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G A A G C A A G C T A G G A A G G T A C C A A G C T A C C A T C C A A G G T T G G A T G G T T G C T A G G T A C C T T G C T A G C A T C C T T G G T A C C A T G G T T G G A T G G T T C G A A G G A A G C A A G C T A C C T T G C A T G G T T G C T A C G A A G G T A G C T T C G A T G G T T G G A T C C T A G C T A G C A A C G T A G C A A G G T A C C T T G C A T G C A T C G T T G G A T G C A A G C A T G G T T C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C A A G G T T C G A T C G A A C C T A C G T T C G T A G C A T C G T A G C A A C C A T G G T T C G A T G G T A C G T T C G A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G C A A G C A T G G T T C C A A C G A T G G T T C G T A G C A A C C A A C G T A C G A A G G A T C G T A C C T T G C T T C G A A G C T T C G A T G G T T C G A A G G A T C C T T C C A A C G T T G C A A G C A T C C A T C G A A C G T T G G A T G C A A G G T A C C T A C G A T G G T T G G T A G G T A G C A T G G A T C C T T G C T T C C T A G G A A C G A T G C T A G C T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C A T G G A T C C T A C C A A C C T A C G T T G C A A G G T T G C T A G C A T C C A T G C T A G C T T G G A A C C A A G C A A C G T A G C A A C G A T G C A A G C A A G G A T G G A A G G A A C C T A G C T T C G T A G G A T G G A T C C T T G C A A C G T T G C T A G C T A G G T T G C A A G C A A C G T T C C T A G C T A G G T T C G T A G C T A C C T A G C A A G C A T G C A A G G A T C G A A C G A T C G T T G C A A C C T A C G T T G C T T G C A T C C A A G C A T C G T T G C T A G G A T G G A T C C T A C G A T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C T A G G T T G C T T C C T A G C A T G C T A G C T A C C A A C C A A C C T A G G T A G G T A G C A A C G T CGU_MN124 # subpop. label: 7 (internally 7) -1 1 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 2 1 2 1 1 2 1 1 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 1 1 2 2 2 2 1 2 1 1 2 1 2 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 1 1 1 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 2 1 1 1 2 2 2 2 2 2 2 1 1 1 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 1 1 2 2 1 2 2 2 2 2 2 1 1 2 1 2 2 1 1 2 2 1 2 2 2 2 2 2 1 2 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 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A G C T T C C T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C C T T C C T A G C A A C C A T C G T A C C T T G G T A C G T A G G A A G C T A G C T A C C T T G G T A G C A A G G A T C G A T G G T A C C T T C G A T G G T T G C T A G G T T G G T T G G A A G C T T C G T A G G T A G G A A G G A T G G A T C C A A C C A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T A C G T A G G T A C G T A G C A A G G A A G C A T G C T T G C A T C C T T C C T A G G A A C G A A G C T A C C A T G C A T C G A T G C A T C C A A C C A A C C T A G C T A G G T T C G A T G C T T C G A A C G T A G C T A G C T T G C T A G C A A C C A A G G T T C G T T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G C A A C C A A G C T A C C A A C G T A G C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G G T T C G T A C G A T G G A T C G T A G G T A G C A A G G A T C C T T C G T A G C T A C G T A G C T T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A G C A T G C A A C C A T G G A T C C T A C G A A C C T T G C T T G C A A G G T T G C T T C C A T C C T T C G A A C G A A G C T A C C T T G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C A A C G T T G G T T C G T A C C T T C C T T G C A A G G T A G C T A G C A T C G A T G C T A G C A A C G T T C C T A C C T A C G T A C C T T G G A A G C T A G G A A G C T A C C A A G G T T C G T A C C A T C G T T G C T T C G A A C C T A C C A A C C A T C G A T C C T A G G T A C C A A G G A T G G T T C C T A C G T A G G A T C C T A G C A T G C T T G G A T G C A T G C T T G C T A C C A A G C T T G C A A C G T T G G T A G C T T G C T T C C T T G C T A C G A T G C T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +A C C T A G G T T C C T T G C T A C C T T G C T A G G A A G C T A C G A A G G T T G C T T G C T T G G T T C G T A C C T A G G T A C C A T G C T T G G T A C C T T G C T A G C A T C G A T G G T T G G T T G G T T C C T T G C T A C C A A C G A A G C T T G C A A C C T T G C A A C C T T C G A A G G T T G G A T C C A T C C T A G C A T C C A A C C T T C C T T C G A A G C T A C G A A G C T T C G T T G C T A G C T A G C A A G G A T G C A A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T C C A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A C C A T C C A A G G A A C G A A C G T T G C A T C G T A G G T A C C A A C G T T G G T A C G T A C G A T C C A T C G T A G C A A G C T A C G T A G C A A G G T T G G A T C G A A G C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T A G G A A C C T A G C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A 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A G G A T C G T T G G A A G G A T C G T A C C T A G G A A C G A T G C T A C C T T G G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G G T T G C A A C C T T G C T T G C A A G G T T G G T T C C A T C C T A G C A A G C T T G C T A C C T A G C T T G C T T G C A A C C A T G C T A G G T T G C A T G G T A C G A A G C A T G G T A C C A A G G T A C G T T G C T T C C A A G C A T C C T A C C T A G C T T G C T T G G A A G C T A C C T T G C T A C G T T C C T T G G T T G C T T G C A A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T G C T A G C A A C G T A G G T T G G A A C G T T C C T A G C T A G C A A C G T A C C T CGU_MN125 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 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C T T G C A T C C A T C C T T C G T T G G T A G G A T G G A A G C A T C G A T C G A T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T T C G A A C G T A C G A A G C A T C G A A G G T A C C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A T C C A A G G T A C C T T G G T A C C A A G C T T C G T T C G A A G G T A C C A T G C A T C C A A C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T A G C A T C C A T G G A A C G T T G G T T G C A A C C A A G G T T G C A T G G A T C G T A G G A T C G T T C G A A C C T T C G T A G C T A C G T A G C T T G C T A G C T T G G T A C C A T G G T T G C T A G G A A C G A T C C T A G C T A G C A T G G T A C C T T G C A T C G A A C G A A C C T T G C T A G C T A G G A T G C T T C C A T C C A T G G A A G C A A G G A A G C T A G C T T G C A A G C A A C C A T G C A A G C T A G G T T G G T A G G A T G G A T C G T T C G T A G G A A C G T T C C T T G C A A C G T T G C A A G C T A G G T T G G A A G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T A G G T A G C A T C C A A G G A T G G A A C C A T C G T T G C A A G C A A C C T A G G A T G C A T C G A A G C T T G G T T G C A A G G A A G C T T C C T A C C T A G G A T G C T A C C T A G C T T G G A A C C A T C C T T C C A A C C A A C C T T G C T T C C T T C C A A G C T T G C T T C C T A G C A A C G T A G C T T G C A A G G A T C C T A G C T A G G A A G C T A G C T +A G C T A G G T A C G T T G C T A C C T T C C T A G G T A G G T A C G A A G G T T C C T T G C T T G G A T G G A T G C T A G G T A G C A T G C A A G C T T G C A T G G T T G C A T G G A A C G A T C C T T C C T A C C A A G G T A G C T A C G T A G C A T C G A T C C T T G C A A C C A T C G T A G G T T G C T T C C A T C C A A C C T T C C A T C C A T C C A A C G T A G G A A C C T A G G T T G G T A G C T T G C A A G C A A G C T T G C T A C C T A C C A A C G T T G G A A G G T A C G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C G A T G C T A C G A A C G T A G G T A G G A A C G A A C C T A C C A A G C A T G G A A G G T A C G A T G C T T C G T A G C T T C G A A G G A T C C A T C G A T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A T G G T A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A A C G T A G G T A C C A A G G A T C G T T C C A A C G A T C G A A C C T A G C T A C C T A G C A T G G T T G C T T G G A A C G T A C C T T G G T T G C A T G G A T C C T A C C T A G G T A C C T A G C A A G G T A C C T A G C A T G C A T C C T T C C A T G C A A C G A A G C T A C G A T G C A A G G A T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C G A A C C T A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T A G C A T G G T A C G A A G C T T C C T A C G T A G C A A C C T A G G A A G G A A G G T A C C A T G C T T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A A G C A T G C A A G G T A C C T A G G T A C G T T G G A T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A G G A A G G A A C C A A G C T T G G T A G G A A C C A A C G T T C C T T G G T T G G T A G G A A G G A T G C A T G G T A G G A T G G T T C C T T C G T A C G T A G C T A G C A T G G T T G G A T G C A A G C T A C G T T G C T A C G T T C C T T G G T A G C T T C G T A G C T A C C A A G G A A G C T A C C A T C G T T G C A A C C T A C C T A C G A T C G A T C G A A G C A A G G T A C C A T G C A T G G A T C G T A C G A T G C T T G C T A C C A T G C T T G C A A C C A T C C T A G C T T C C A A G C T T G C T T C C T T C C A A G G T T G C T T C C A A G G A T C G A T G C T A G C T A G C T A C G T A G G T A G G A A G G T A C C T CGU_MN126 # subpop. label: 7 (internally 7) -2 1 1 2 2 1 1 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 2 1 2 1 2 1 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 2 1 1 1 2 1 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 2 1 1 2 2 1 2 2 1 1 2 1 2 2 2 2 2 1 1 2 1 1 2 1 1 2 2 1 1 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 2 1 1 1 2 2 2 2 2 1 2 1 2 1 1 1 2 2 1 1 2 1 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 1 1 2 1 1 2 2 1 1 2 2 2 1 2 1 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 1 1 2 2 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 2 1 1 2 1 2 1 1 1 2 2 1 1 2 2 1 1 1 2 2 2 1 1 2 2 1 2 2 1 2 1 1 1 1 2 2 1 2 1 1 1 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T C G T T G C T A G G A A G C T A C C T T G C A A G C A A C C A A C C T T G C T T G C A A G G A T G C T T C C A T C C A T C G A A G G A A G C T A G C T T G C T A C C T T G G A A C G A T G C A A G C T A G G T T G G T A G G A T G C T A C G T T G G A A G G A A G G T T C C T T G C A A C G T A G C T A G C A T G C T T G G A T G C T T C G T T C C T A G C T A G G T T C C T A G G T T G C T A G G T A G C T A C G A A G G A T G G A A C C T T C G T T G C T A G C A A C C T A G G A T G C A T C G A A G C A A G G T A C C A T G C A T G C T T C C T A C C T T G C T T G C T A G C T T C C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN127 # subpop. label: 7 (internally 7) -2 2 1 1 2 1 1 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 1 2 2 1 1 2 2 2 2 1 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 2 2 1 1 2 2 1 1 1 2 2 2 1 2 1 2 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G A A C G T A G G T A C C A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A C C T A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C A T C G T A C G T T G C T A C G A A C C T T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T T G G A A G G T T G G T T G G A A G C T T C G T T G G T A G G A A G C A T G C A A G C A A C G A A G G A A C C A A G G T T C G T A G G A A G G T T G G A A C C T A G G A A G C T T G G T T G G A T G G A T G C T A G C T A G G T A C C T A G G A A G C A A C C T A G C A A C C A A C C T T G G A T G C A A G G A A G C A A G C A T C G A T C G A T G C A T G C A A C C A A C C T T G G A A C C A A G G T A G C A A G G T A C G T T G G A A C C T A G C A T G G T T C C T T G G T A C G A A C C A A C C T T G C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T C C A T G G T A C G A T G C T A G G T A G G T T G C A T G C T A C G T T C G A A G C T A C C T T G C T T C G A A C C T T C G T T G C T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T T G C T A C G A A G G T T G C T T G G T T G G A T G C A T C C T T G C T T G G T A C G A A C G T A G C T A G C T T G G T A C C A T G C A T C C T A C C A A C C T A C G T A G C T T C G A A C G T A C C A T C C T T G G A A G C A A G C T A G C A A G C A A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A G C T T C G T A C G A A C G T T C G T T C C T A G C A T C C T A G C T A G G T T G G T T G C A A G C T A C C T A G C T A G G T T C G T A G C T A G C A T G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G G A T C C A T C C A A G C A T C G T T G C T A G G A T G G A T C C T A C G A T G C T T G C A A C C T T G C T A G G A A G C T A C C T A G C T A C C A A G G T T C C T T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T C C T A G G T A C C T A G C T A G C A A C G T A C C T +A C C T A C G T A C C T A G C T A C C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T T C C T T C G T A G G T T G G T A C C A T C G T A C G T A G G A A C C A T G C T T C G T T G C A A C C T T C G T T G G T T G C T A G C A T C G T A G C A A G G A T C C A T C G A A G G T A G G A T C G A A G C T T C G T T G C A T G G A T G G A A G G A T G C A A G C T A G C T A C C T T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A G C A T G C T A C G A A C G T A G G T A C C A A C C T A C G A T G C A A G G T T C C A T C G T A C G A T G C A A G C A A C C T T C G T A C G T A G G A A C G A T G G T T C G T T C C A T C G T T C G T T G C A A C G A A C C A T G G A A C C A A G C A T G C A T C C A A C C T A G C T A G G T T C G A A G C A T G G A T G G T A G C A T G C A A C G T T C C A T G C T A G G T A G C A T C C A A G G T A G C A T G G A A G C T T G G T T G C A A C G A A C G A A G G A T G G A A G C T A C C A T G G T A C G T T G C A T C G T T G C T A C G T T G G A T C C T A C C T T C C T T C G T A C C A T G C T A G G A T G C A A C C A A G C T A G C A A G C T A G C T A G C A T C G T T C C T A C G A A G G A T G C T T G G T T G C T T C G A T C C T A G C T A G G T A C C T A G C T T G C A A C C T A G C A A C C T T C C A T G G A T G G T A G C A T G G A A C C T A C G A A G C T A G C A T C C A A C C A A C C A A G C A T G C T T C G T A G C A T C G T A C G T T C C T A G C A T G G T A G C A A G C A A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T A G C A T G G T A C G A A G C T T C G T A G C A A G C A A C G T A C G T T C G A A G C T A C C T T G C T A G C A T G C T T G C T A G G T T C C T A G C A A C C T A G G A T G C T T C C T T C C T T C C T A G G T A G C T A G G T T G C A A G C T A C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C A T G C T A G G A A C C T T C G A T C G A A C G A T C C T T G C T A G C A T G G T T G C T A C G A T C G T T C G A A C G A A G G T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G A A G G A A C G A A C C T T G G T A C G A A C G T T G C T T C C T A C G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G A T C C T A C C T A C C T A C G T T G C A T C G A T C C T A G G T T C G A A C G A T G C T A G C T A C G T A G G A T G C T A C C A T G C T T G C A A G C A A C C T T G C T A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G C T A C G T A G 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T G C T T C C T T G C T A C C A A C G T A G C T T G C T A C G T T G C A A C C T A C G A T G G T T G C T T G C A T C G T A G C A A G G A T C C T T C C A T C G A A G G A T C G A T C G A T C G T A C C T A G C A A G C A A G G T A G C T A G C T A G G A A C C T T C C T T G C T T G C T A G G T T G G T A G G T T G G T A G G T A G C A T G C T T G G A T G G T A G C T A C C A A C G A A G C T A G G A T G G T T G G T T G C A A G C A T G C T A C C A A C G T A G G T A C C T A C G A A G G T T G G A A G C T A G G A A C G T A C G A T G C A A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A G G A T G G T A C G T T G C A T G C T A G G T A G C A A C C A T C G T A C C T T G G T A C C T A G C A A G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A C C A T C G A T G C T T G G A T G C T A C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G A T G C A A C C A A G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T G G T T C C A T G G A A C C T A G C A A G C A A G C A A G C T A C G A T G G A A C C T T C C T A G G T A G C A T C C A A C C A T C C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G A T C C T A G C A T G G T T G C A A G G A T C C A A G G A T G C T T C C T T C C T T C C A T G G T T G G A T G G T A C C A A G G T T C C T A C G A T G C A T C G T A G G T A G C A A C G A T C G A T C G T A G C A T C G A A G C T T G C T A G C T A C G T A C C A A C C A T G C T T G G T A C G T T G G A T G C A T G C T T G C A A C C A T G G A T C C T T G C A A C C T T G C T T G C A A G G T T G C T T C C A T C C T A G C A A G C T T G C T A C C T T G C T T C C T T G C A A C C A T G C A A G C A T G C A T G G A A G G A A C G A A C C T T C G T T C G T A C G A T C C T T C C T A G G T T C C T A G C T A G C A T C C T T G G A A G C T A C C T T G C T A C G T T C C T T G G T T G C T T G C A A G C T A G G A A G G A A G C T T C C A T C G T A G C A A C C T A C C T A C C A T C G A A G G A A G C T A G G T T G C A A G G T T C G T T C G A A C G A A C C A T G C T A C C T T G C T A G G A A C C A T C C T T G C T A C G A A G C T T G G T T C C T T C C T A G G T T G G T T C C A A G C A A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C T A C G T A C C T T C C T A C G T T G C T A G C T T C G A A C C A A G G T T G C T T G C A T G G T T C G A A C C T T G G T A C C A T G C A T G C T A G C T T G G T A G C A T G C A T G G T T C G A T G G T A G C A T C C T A C C T A G G T T G C A T C C T T C G A T G C A A G C T T C C A A G C T T G G T T G C A T C C T A G C A T G C A T G G T T C C T T G G T A G C T A G C T A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G G A A C C T T G C A A G G T T G G T A G G T T G G T A G G T T C C A T G C T A G G A T G C T T G G A T G G A A G G T A C C A A C G A T G C T A C G A A G C T T C G T T G C A A G C A T G C T A C G A A C G T A G G T A C C T A C G T A C G A T G C A A G G T A G G A A C G T A C G A T G C A T C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T G C T A G C A T C C T T G G A A G G T A C G T T G G T A C G T T G G T A C G T A G G A A C C T A G G T A C C A A G C T T C C A T C C A A G C T T G C A T C G T T G C A A G G T T G G T T G C T T C C T T C G T T G G T A G G A A G C A T G C A A G C A A C G A T C G A A C C A A G C T A C C T A G C A A G G T T G C T T G G A A C G T A G C A T C G A T G G T T G G A T C C T A G C T A G C T A C C T T G G A T G C T A G C T T C G A T G C T T C C A T C C A A G G T A G G T T G C A A C C A T G G A T C G A T C C A T C C A A G C A A G C T T C C T T G C T T C C A T G C A T C G T A C C T A G C A A G C A T G G A A G G T A G C T T G C T A C G A A G G T A C G T A C C A A G G T A G C T T C C T T G C A T G C A A C C T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A C C A T C C T A C C T T C C T A G C T A G G T T G C T A C G A T C C T T C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G T A C G T A G G T A G C A A G C T T C G T A C G A T G G A T C G T A G G T A G C A A G G A T C C T T C G T A G C T A G G A A C G A T G C T A C C T T G G T A C C A T G G T A G C T T G G T A C G T T G G A T G C A T G C A T G G A A C C T T C G A T C G A A C G A T C C T A G G T A G C T A C C T A C G T A C C A T C C T T C G A A G C A A G G T A G C T A G C T T C C T T G C T A C C A A C G T T C C T T G G T T G G T A G G A A G C A A C G T T G G T T C G T A C C T T C C T T G C A A G G T A G C T A G C A T G C T T G G T T C C A A G C A A G G T A C C A A G C T T C C T A G G T T G C A T G C T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C G A A G G A T C C A A G G T A C C A T C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C C A T C C T T C C A T G G T T G C A A G C T T G C T T C C T A G C A A C G T T G C T A G G A A G C A A C G T T G C A A G C A A C C T A G C A CGU_MN132 # subpop. label: 7 (internally 7) -2 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 1 1 2 2 1 1 1 1 2 2 1 1 1 2 1 2 2 1 2 1 1 1 2 2 2 1 2 1 2 2 1 1 2 2 2 1 1 1 2 2 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 1 1 2 2 1 1 2 2 2 2 2 1 2 1 1 2 1 2 1 1 2 1 2 2 2 2 2 1 2 1 2 1 1 1 2 2 1 2 2 2 2 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 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G A A C G T A C G T T G G A T C C T T G C A T G G T T C C A T G G A A G C A T C G A A G G A T G G T T C G T A G G A A C C T A C C T A G C T A C C A A G C T A G G A T G G T A G C A T G C A A C C T T C C A T G C A T G G T A G C A A C G T A G G T A C C T T G G T A C C A A G C A A G C T A G C A T G G A T G G T A C C A T C G T A C G A T G G T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A C G T A C G A A G C T T C G A A C C A A C G A A G G A A G C T A G G T A C C T A G C A T G C A T G C T A G G A A G G T A G C A A C G T A C C A T G G A T C C T A C G T A G C A A C G T A G C A A G C T A C C T T G C A T G C A T C C T T C C T T G C A A G C A T G G A A C C A T G G A A G G A A C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A A C C T A C G A T C G A A G C T T G C A A G G T A C C T T G C T A C G A A G G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C C A A G C T T C C T T G C A A C C A A G C T A C C T A C G A A C C A T G C T A C 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C T T G C T A C C T A G G T T C C T A G G T T C C T A G G T A G G T A G C A A C G T +A C C A A G G T A C G T T G C T A C C T T C G T A G G T A C G T A C G A A G G T T G C T T G C T T G G T T C G A A C C T A G G T A G C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G C T T G C A A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G T A G G A A C C A A G C T T G G T A G C A T G C A A G C A A G G T T G C A A G C T A G C T A C C A T G C T A G C T A G C A A G G T T G G T A G G T T G G T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A G G A T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C T A C G T T C C T T C G A A G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T C G A A C C A T C G T A G G A A G G A A G C A T G G A T C G T A C C A T G C A T C G A A G G A T C G T T G C A T C C T T G G T A G G T A G G T T G G T A C G T T C G A A G C A A G C A T G G T A G G T A C C A A G C T A C C A T C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T T G G T T C G A T C C T A G C T A G C A T G C T T G C A A C C T A C C A T G G T A G C A T C G T A G G A T G G T A G G A A G C T A C C A T G C A A G G A A G C A T C C A A G C A A C C T A C C T T G G T T C G A A G C T T C G A T C C A T G G A A G C T T G C T A G G T A C C A A C C T A C G A A C G T T C C T A C C T A G G T A C C T A G C T T G C T T G C A A G C T T G C A T C G A A G C T T C C T T G G T A C G A A G G T A G G T A G G T A C C A T G C T A C G A A G C T T G G T A C G T T G C T T C G A T C C T A G G A A C G A A G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T T G C A A C C A A G G T A C C A T G G A T G G T A G G A T G C T A C G A T C C T T C G T T C C T T C G T A G G T T G C T T G G T T G G A A C C T A G G T A C C T A G G T A C G T A C C T A G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A C C T A G C T T G C A A G G A A C C A T G C A A G G T T G C A T G G T A C G A A G C A T G G T A C C A A G G T A C G A T C C T T C C T A C G T T G C A A C C T T G C A T G G A T G C A A G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C C T T C C A T C C A T G C T T G G A T G C T A C C A A G C T T C G A A C G A T G G T T G C T A C C A T C C T A G G A A G C A A C C T A G C T A C C T A G C T T G C A T C G T T G C A A G C T T G G T T G C T T G C A A C G T A G C A A G C A A C C A A C C T A G G T A G G T A G C T A G C A CGU_MN133 # subpop. label: 7 (internally 7) -2 2 2 2 2 1 1 2 2 1 1 2 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2 1 2 2 2 2 1 2 1 2 1 2 1 2 2 2 1 2 2 1 1 2 2 2 2 2 1 2 2 1 2 2 2 1 1 1 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 +T G C T A C G T A C G T T G C T A C C T T C G T A G G T A C G T A C C A A G G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G T T G C T T G C A A G C A T C G T A C C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C A A G G A T C C A T C G A A C G A A G G A A C C A A G C T T G G T A G C T T G C A A G C A A G G T T G C A A G C T A G C T A C C T T C C T A G C T A G C T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T T G C T T C G A A C C A T G C A A G C T T G G A A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A T G G T A C G T T G C T T C C T T G G T A G C A A C G T A C G T A G C A T G G T A G G T A G G A A G C A A G C T A G G A A G G T A C C A A G G A T C C A A C C T A C G T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A A G C A T C G A T G G A T G G A T C C T T G C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G C A A C G A T G G T A C C A A C G A A C C A T G C T A C G A A G C A A G G T A G G A T G C A T C G A T C C T A G G A A G G T T G C A T C G A A C C T A G G A T C G T T G C T T C C T T C C A T G G T A C G T A G G T T G C A A G C A A G C T T G G A T G G A T C G T A G G A T C G T T C G A A C C T T C C A T C C T A G C T T G G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T T C G A T C C T T C G T T C C A A G G A A C G A A G C A A C C T T G G A A C C A T G C A T G G T T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T G G T T C C A A G C A T C C T A C C T A G G T T G G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C A T G C A A G G A A G C T T C C A T C G T T C C A A C C T A C C A A G C A T C G A T C G A T G C T T G G A T G C T A C G A A G G A T C G A A C G A T G C T T G C A A C C T T G C T A G G A A C C A T C C T A G G T A C C A T C C T T G C T A C G T T G C A A G C T T G C T T G C T A G C T A C G T A G C T T C G A A G G A A C C T A G G T A G G T A G C A A C G T +A C C A A G G T A C G T T G C T A C C T T C 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G T T C G A A G G A A G G T A C C A T C G T T C G A T G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C C A A G C T A C G T T C C A T C C A T C G A A C C A A G C T A C C T A G C A T G G T T C C T A C C T A G G A T C C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G G A A G C A T G C T A C C T T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C T T G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G G T A G C T A G C A T C G A T G C T T G C A T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G T T G C A T G C T A C C T A G G T T C G T T C G T A C C T A G C T T G C T A G C T A C C A A G G A A G C T T C C T T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A A C C T A C G A A G C T T C C A A C G A T G C T T G G T A C C A A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A G C A T C C T A G C T A G G A A G C T A G C T CGU_MN135 # subpop. label: 7 (internally 7) -2 1 2 2 2 2 1 1 1 1 2 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 1 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 2 1 1 1 2 2 1 1 2 1 2 2 2 2 1 1 1 2 1 2 2 2 2 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T G C A A G G T T G G T A G G T T G G T A G G T T G G T A G G T A G G A A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T T C C T T G C A A C C A T C C A A G G A A C G A A C G T T G C A T C G T A G G T T G G A A G C T A G G A A C G T A C G A T G C A A C C A A C C A T C C A A G G A T C C T T C G T T G C T T C C T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G C A A C G T T G C A T G C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C T A G G A T G C T A C C A A G G A A C C A A G C T A C C T A G C A T G C A T G C T T G G A A C G T A G C A T G G A T G C T T G G A T G C T A C G T A G G T A C G T T G G A T G C T A G C T T C G A T C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A 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T C C T A G G T T G C A T G C T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +A C C T A C G T A C C T T G C T A G C T T G C T A G G T T G G T A C G A A G G T T G C T T G C T A G G A A G G A A G C T T G G T A C C T A C C T T G C T T G C T T G G T T C C T A C C T T C G T A G G T T G G T T C C T T G C T A G C A A G G A A G C T T G G A A C C T T G C A A G C T T C C T T G G T T G C T T C G A T C C T A G C A A G G A A C C T T C C A T G G T A G C T T G C A T C G T T G G T A G C T T G C T A G C A A G G A T G C A A G C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T C C A A C C T A C C T A G C T A C G A A C G A A G G T T C C A A C G A A G C T A G G A A G G T T G C T T G C A A G C A T G C T A C C A A C G T A G G T A C C T A C G A A C C T A G G A A C G T T G G A A C G A A C G A T C C A T C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A C C A T G G T A G G A T G G T A C G T A G C T T G C T A C C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C A A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C A A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G C A A G G A A C C A A G C A A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G T A C C A T C G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G A A G C T T G C T A G C T T C C T T C C A A G G T A G G T T G C A A G C A T C G A A G C A T C G A T G C T T C C T T G C T T G C T T G C T T C G A T C C T T C C T T C C T A C C A T G C T T G C T A G G T A C C A A G C T A C G A T G G A A C C T T C C T A G G T A G C T T C C T T G C A T G C T A C C T A G C A T G C A A G C T T C C A T G G A A C G A A G C A T C C T A G G T A G G A A C G T A G G A A C C A A C G A A C C A A C C T T C G A T C C T A G C A T G G T T G C T A G G A T C C A A G G A T G C T T C C T T C C T T C C A T G G T T G G A T G G T A C C A A G C T T C C T A C G A T G C A T C G T A G G T A G C A A C G A T C G A T C G T A G C A T C G A A G C T T G C T A G C A A C G T A C C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T T C G T A C G A T C C T T C C T A G G T T G C T A G C T A G C A T G G A T G C A A G C T A C C T A G C T A G G T T C G T A C G T A G C T A G G T A G C T A G G A A G G A A G C T T C C A T C G T A G C A A C C T A C C T A C C A T C G A A G G A A G C T A G G T A C C A A G G T T C G T T C G A A C G A A C C A T G C T A C C T T G C T A G G A A C C A T C C T T G C T A C G A A G C T T G G T T C C T T C C T A G G T T G G T T C C A A G C A A C C T T G C T A G G A A G C A A C G T T G C A A G C A A C C T A G C A CGU_MN136 # subpop. label: 7 (internally 7) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 1 2 1 2 2 2 2 1 1 1 2 2 1 1 1 1 2 2 1 1 1 2 1 2 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 1 2 2 2 2 1 2 1 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 1 2 1 1 1 2 2 1 1 1 1 1 2 1 2 2 2 2 1 2 2 2 1 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 2 1 2 1 1 2 1 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 1 2 2 2 2 1 2 2 2 1 2 1 2 2 2 2 1 2 1 1 1 1 2 2 2 1 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 2 1 2 2 1 1 1 1 1 1 2 2 1 1 2 1 1 1 2 2 1 2 2 2 1 1 2 1 1 2 1 2 1 2 2 2 1 2 2 1 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C T T C C T A C C T T C G A A G G T A G G T A G G A A G G T T G C T T G C T A G G T T C G A A C C T A G G T A C C A T G C A T G C T A G C A T G G T A G C A T C C T T C G A A G G A T G G T A C C A T C C T A G C T A G G A A G C T T G G A T C G A T G C A A G C T T C G T T G G T T G G T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C G T T C C T A G C T A G C T A G G T T G G T A G G T T C C T A G G T A G G T T G C T A C C A T C G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A G G A T C G A A G G A A C G A A G G T A G G A A C G T T G G T A G G T A C G A T C C T T C G T A G C T T C G A A G G A A C G A A G G T T C G T T C G T T G C T T G C A T G G T T C C A T G G A A G C A A C G A A G G A T G G T T C G T A G G A A C C T A C C T A G C T A C C A A G C T A G G A T G G T A C C A T G G T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G T A C G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G G A A G C T T C G T T G G T A C G A A G C A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A C C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C C T T C G T T G C A A C C A T G G A A C C A T G C A A G C T T G C A T C C A A C C T A G C T T G C A T G G T T C G A A G G A T C G T A C C A T C G A A G C A T G G A A G G T A C C A A C G T A C G A A C G T T C C T A C G T A G G T A C C A T C C A A C C A T C G T A G G T A G C A T C G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G T A G G T T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C G T A G G T T G C A A G C T A C G T A C G A T G G A T C C T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A G G A T G C T A C C T T G G A T C C A T G G T T G G A T G G A A C G T T G G A T G C T A G C T A C C T T C C T T G C A T C C T A C G T A C C T T G C T T G C A T C G T A C C T A C C A T C C T T C G A A C G A A G G T A C C A A C C T T C C T T G G T A C C A T G C A T G C A A G G A T G G A A G G A A G C T A C C T T G G T A G C A A C C A T C C T T C C T A G C T T C C T A G C A A G C T T C G T T C C A A G C T A C G T A G C T A C G A A C C T T G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A C G A T C G A T C G A A G C A T C G A T C G T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G C A A C G A T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T C C T A G G A A C C T A G G T A G G T A G C T A G C A +A G G T A C G T A C G T A G C T A C C T T G G A A G G T T G G T A C C T A C G A T C C T T G C T A C C T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G A A C G A T G C T A G C A T C G T A C C T A G G A A C C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G C T A G C T T G C A A C C T T G G T T C C A T C G T T C C T A G C T A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C C A A G G A T C C A T C C T T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T G G A A G C T T G G T T G C T A G C A A G G A A G G T A G G A A G G T A C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G C T T C C T T C G T T G G T A C C A A G G A T G C A A G C T A C C A A G G A A C C A A G G T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T C G A T G C T T C G A T C C T A C C T A G G T A C C T T C C A A G C T A C C A T G C T T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A G C T A C G A A C C A T G C T A G G A A G C T A G C T A C G T T G C T T C G A A C C T T C C A T G G T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A G G T T G C A A C C A A G G T A G C A T G G A A C G T A G G A T C G T A G G A T C C T T C G T T G C T T C G A A C G A T G G T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T A G C A A G G A A C C T T G C A A G C A A C C A A C C T T G C T T G C T T G G A T G C T T C C A T C C T T C G T A G G A A G C T A G C A A G C T T G G T A G C A A C C A T G C A A G G T T G G A T G G A T G C A A C G A A C G T T G G A A G G A T G G A T C C T T C C A A G C A T G C T A C C T A G C T T G C T T G G A A G C T T C C T A G C T A G G T T C C T T G G T A C G A T G C A A G C T T G G A A G G T A C C T T C C T T C G T T G C A A C G T A C C A A G C A T G G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T A C C T A G C T A C C A T C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G C A A C G T A C C T A G C T A G C A A C G T A C C T CGU_MN137 # subpop. label: 7 (internally 7) -2 2 1 2 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 1 1 2 1 2 2 2 1 2 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 2 1 1 1 1 1 1 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 1 2 2 2 2 1 1 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 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A C G T T C C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A A G C A T C G A A C C T T C G T A G C T A G C T T G G A T G C T A C C T T G G T T G C T A G G T T G C T A G G T A C G T T C C A A G C T A C C A T G C T A C C A A G C A T G G T T G C A A C C A A C G T T G C A T G G T T G G T A G C A T C C T T C G T A G G A A G G A A C C A T G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G A A G G A T G C A A G C T T G G T A G G A T G G T T C C T T C C A A G C A T C C T A C C T A G G T T G G T T C C A A G C T T C C T T G G T T C G T T C G T T C C T A G C T T C G A A G C A T G C A A G G A A C C A A C C A T C G T T G C A A C C T A C C T A G C A T C G A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G G T T C C T T G C A A G C A A C G T A G G T A C C A A C C A A C C T A G G T A G G T A G C A A C G T CGU_MN138 # subpop. label: 7 (internally 7) -2 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 1 2 2 2 2 1 2 2 1 2 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 1 2 2 1 1 2 2 1 1 1 1 2 2 1 1 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 1 1 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 2 1 2 1 1 2 1 2 1 1 2 1 2 2 2 2 2 1 2 1 2 1 1 1 2 2 1 2 2 2 2 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 1 2 1 2 2 1 2 2 1 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 2 2 1 1 1 1 1 2 1 1 1 1 2 2 2 2 2 1 1 1 2 1 2 1 2 1 2 1 2 2 1 2 2 2 1 1 2 2 2 2 1 2 1 2 2 1 1 2 1 1 1 1 2 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 1 1 2 2 2 1 2 2 2 1 2 2 1 2 1 1 1 2 2 2 1 1 2 2 1 1 1 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 1 1 2 2 2 2 2 1 1 2 1 2 2 2 2 2 1 1 1 2 2 1 2 1 1 2 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C A T G C T T G C A A C C A T C G A T C G T A G G A T C G T T C C T T C C A A G C A T G C T A G C T A G C A T G G A T G C A A G C T T C C T A G C T A G G T T C C T T G G T T G C T T C G T A G C A T G C A A G G A A G C T T C C A T C G T T G C A A C C T A C C A A C G A T G G A T C G A A G C A T C G A T C G T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G C A A C C A T C C T A G C T A C C A T C C T T G C T A C C T T G C A A G C T T G G T T G C T A G G A A C G T A G C T T G C A A G C A T C G A A G C T A C C A A G G T A C C T CGU_MN139 # subpop. label: 7 (internally 7) -2 2 1 2 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 2 2 1 1 1 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 2 2 2 2 1 2 1 2 1 1 2 1 1 2 1 2 1 2 1 2 1 2 2 1 1 2 2 2 2 2 2 1 1 1 2 1 1 1 1 1 2 1 1 2 1 2 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 2 1 1 1 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 1 2 2 2 1 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C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T C C A A C C A A C G T T G C A T G C A A G G T A G C A A C C A T C G T A C C T T G G T A C C T T G G A A G C T A G C T A C C T T G G T A G C A A G G A T G C A A C C T A C G T T G C A A C G T A G C A A C G T A G G T T G C T T C C T T C G T A G G T A C C A A G C A T G G A T C C A T C C T A C G A A G C A A G G T T C C T A G C A T C G T T C C A A G G A A G G T A G C T T G G A T G G A T C G A T C C T A C G T A G C T A C C T A G G A A G C T A G C T T G C T T C C A T C C T A C G T T C G A A G C A T G G A A C C T A C G A T C G A T C G A T G C T T C C T T G C T A G C A A C C T T C G A A G C A A C G A A C G A T C G A T G G A T G G A T G G T T C C T A G C T A G C A A C C A A C C T T G G A A G G T A C C A A G G T T G C T T G C T A G C T A G C A T C G T A G C T T C C A T G G T A C G A T G G T A G G T A C C A A G C A A G C T A G G A A G G A A G C T A C G T T G C T T C G A T C C T A C G A T G G A A G C A T C G T A G C A A G G A T G C T T G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G T T C G T A G C A A G C A T C G A A C C T T C G T A G C T A G C T T G G A T G C T A C C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A T C C T T C G T A G G A A G G A A C C A T G C T A C C T T C C A A C C A T G C A T G G T T G C A T G G A A G G A T G C A A G C T T G G T A G G A T G G T T C C T T C G T A C G T A C C T T G C A A G G T T G G A T C C A A G C T T C C T T G C T A G G T T C G T T C C T A G C T A G G T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +A C C T A G G A T G C T T C G A T G G A T G C T A G G T T G G T A C C A A G G A T C C T T G C A A C G T T G G A T C C A T G G T A G C A T C C A A C C A A C C T T G C T A G C A T C C A T G G A T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C T T G G T T G G T T C C A T C C T A G C A T C C A T C C T T G C T T G G T A G G A A C C A T G G T T C G T A C C T A G C A A G C A A G G A T G C A A G C T A G C A A C G T A C C T A G C T A C C T A G G T T G G T A C C T T C C T A G G T A G G T A G C T T G G A A C C A A G C T T C C A A C G A A G G T A G G T T G C T A C C T T G C A A G C A T G C T A C G A A C G T A G G T A C G A A C C T A C G A T G C A A G C T A G G A A C G T A C C T T C C A A C G T A G G T T C G A A C G A A C C T T C G T T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T G C A A G G A T C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G T A G C T A C G A T G C T T G G A T G C T A C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G A T C C T A G G A T C C T A G C T T C C T T C G T A G G A T C C T A G G T T G C A A C C A A G C T T G G A T C G A T C G T A G G A T C G T T C G A A C C T T C G T A C C T T G G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C A A G C T A C C A T G C T A C C T A G C A T G G T T G C A A C C A A C G T T G C A T G G T T G G T A G C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C C T T C C T T C C A A G C A T C C T A C C T A G C A T G G A T G C A A G C T A C C T A G C T A G G T T C G T A G G A A G G T A G C A A G C A T G C A A G G A T G C T T C C A T C G T T G C A A C C A T C C T A G C A T G C A T C G A T C C A T G C T A C C T A C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G C T T G C T A G G A A C G T A G C T T G G A A C G T A C C T A G C T A G G T A G C A A C G T CGU_MN142 # subpop. label: 7 (internally 7) -2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 2 2 1 2 2 2 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T G C A A G C A A G G T T G C T A C C T A G C A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T A C G T A C C T A G C A T C G A A C G A A G G T A G G A A G C T T G G T T G C A A C C A T C C A A C C A A G G A A C G A A G G A A C G A A G G T A C C A A G C A T C G A A G G T A C G T T G C A T C G T A G C T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G G T T G C A T G G A A C C A T C G T A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C T T C C T T G G T A G C A A C C A A G G T A C G A T G G A A G G T A G G A A G C A A G G A T G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C A T C G A A C C T A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A A C G A T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G G T T C C T T G G A A C C A A G C A A G G T T G G A T G G T A G G A T C C T A C C T T G G T A G G A A C G T T C C T T C G T A C G T A G C T A G C T A G C A T G G A T G C A A G C T A C C T A G C T A G G T T C G T A G C T A G C T T C G T A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A G C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C T T G C T T G G A A C C A A C C T A G C T A C C T A G C T T G C A T C G T T G C A A G C T T G G T T G C T T G C A A C G T A G G T T G C A A C C T T C C T A G G T A G G T A G C A A C G T +T G G T T G G A T C C T A G C T A C C T T C G A A G G T A G G T A C C A A G G T T G C T T G C T T G G T T C G A T C C A T G G T A G C A T G C T T G C T A C C T T G C T T C C A A C C T T G G T T G G T T G G T T C C T T G C A A C G T A G G A A C C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T G G A T C C A T C C T T C G T A G G A A C G A A G C T T C G T A G C T A G C A T G G A A G G T A G C T A C C T A G C A A C G T T C C A A G C T A G C A A G G T T C G T A G C T A G G A A G G T A C G T A G C T T G G A A C G A T G G A T C C A T G G A T G C T A G G A T G C A A C G T T G C A A G C A T G C T A C C A A G G A A C G A T G C T A C C T A C G T A C C A A C G T A G G T A G G T A C C A T C C T A C G T A C G A A G C T A C G T T G G A A C C T T G G A T C G A A G C T T G C A T G C T A G C T T C G T T C C A T G G A A C C A A G G A A G G A T G G A A C C A T C G T A G G A A G G A A G C A T G G A T C G T A G C A T G C A T C G T T G C A T C G A A G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G A A G C A A G G T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A T C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T T G G T T G C T T G C A A G C A T G C A T C C A A G C T T C C A T C G T T G C A A C C A T C G T A C G A T C G A T C G A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C A T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T CGU_MN143 # subpop. label: 7 (internally 7) -1 2 2 2 2 2 1 1 1 2 2 2 1 1 1 1 1 2 1 1 1 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 1 1 1 2 1 2 2 1 2 1 2 2 1 2 1 1 1 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 2 2 1 1 2 1 1 1 1 1 2 1 2 2 1 2 2 2 1 1 1 1 2 2 2 2 2 2 2 1 1 1 2 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 1 2 1 1 2 1 2 2 2 2 2 2 1 1 1 2 2 2 2 1 1 1 2 2 2 2 1 2 2 2 1 2 2 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 2 1 2 2 2 2 2 1 2 2 1 2 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 1 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 1 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 1 1 2 1 2 1 2 2 1 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C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G T T C G T T G C A T C C T A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G T A G C T A C G T T G C T T G G A T C C T T C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C C A A G G T T C C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A A G G A A G C T A C C T T G G T A C G A A G C T T C C T A G C A A G C A A G C T A C G T T C G A A C G T A C C A T G C A T C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T A G C A T C C A T G G T A C G T T G G T T G C A A G C T A C C A A G C A T G G A T C G T A G G A T G C T T C G A A C C T T C G T A C C T A G C T A G G A T G C T T G C T T G G T A C C T A G G T T G C T A G G T A C G T T G G A T G C T A G C A T G G A T C C A A G C A T C G A A C G A T C C T T G G T A G C T T C G T A C C T T G G A A C C T A G C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G A A G G A T C C T A G G A A C C T A G C A A C C A T C C T T G C A T G C A T G C A A G G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A A C C A A G G T A G C A A G C A T G C A A G G A A C G A A C C T T C G A T G C T A C C T A C C T A G C A T C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T CGU_MN144 # subpop. label: 7 (internally 7) -2 2 1 2 2 1 2 2 2 1 2 2 1 2 2 1 1 2 2 2 1 2 2 2 2 2 1 2 2 1 2 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 1 1 1 1 1 2 1 2 1 2 2 2 2 1 1 1 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 1 1 2 1 1 1 1 1 2 1 2 2 1 2 2 2 1 1 1 1 2 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T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A C G T A C C T T G C T T G C A T C C A A C G T A G G T T C G A A C G A A C C A A G G A T C C T T G C A A G C A T G C T A G G A A C G T A G G T A G C A A G C T A C C A A C C A T C G A T C G T A G G A T G C T T G G A T C C T T C G T A C C T T C G A A C G A T G C A T G G A T G G A T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C A A C C A A G C A A G C A T G C A T G G A A G G A T G C T T G G A T G G A T C G A T G G A T C C T T C C T A C G T T G C T A G C A A G G T T G G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G G A A G C T T C C A 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T G C A A G C T T G G A A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G G T A C G T T G C T T C C T T G G T A G C T T G G A A G G T A C C T T G G T A C C T A G C T T G G T T C G T A G G A A G G T A C C A A G G A T G C A A G G T A C G T T G C T A C G T A G G A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A C G A A C C A A G C T A C C T A G C A T G G T T G G A A C G A A G G T A G C T T G G A T G C T T C G A T C C T A G C T A G G T A C G T A G C A A G C T A G C A T G C T A C C T T C G T T C C T T G C A A G C A T G G T A C C A T G G A A G G T T G C A T G C T T C C A A G C T T G C T T G C T T C G A A G C A A C C T T C C T T C G A T G G T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A 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T G C T T C G A A C G T A C C A A G C A T G G T A G G T A C G A T G C A A C C T A G C T T C G A A G G A T C C A T C G A T G G T T C C T T C G A T C G T A C G T T G C T A C G T A C C T A G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A T C G A A G G T A C G A T G G A A G C T A G G A A G C A A G G T A G G A A G G T A C C A A G G T T C G A T G G T A C C T T G C A T C G A A C C T A G G T A G G T T G G T T C C T A C G A A G G T A C C A A G G A T G C A A G C A T C C A A C G A A G C A A G C T A C C T A G C A A G G T T C C T A C C T A G G A T G C A T C G A T G G A T G G A T C C T A C C T A G C T T G C T A G C A A G G T A C C T T G C A T G C A T C G T T G C T T G C A A C C A T G C A A C C T A C G A T C G A T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A T C C T A C C A T C C T T G G A A C C A T C C T T G G T A G G A T C C A A G G T T G G T T G C T A C C A T G G T T G C T T G C A A G C T A C G A A G C A A G G T T G C T T G G T A C G A T G G T A C C T A C G T A G C A A C G T A C G A A G G A A G C T A C C A T G G A T C G A A C C T T C G A T C G T T G C A T C G A A C C A A G G A A C G T A G C T T G C A T C C A T G G A A C G T T G G T T G C A A G C T T C G T A C G A T G G T T C G T A G G A T C G T T G G A A G C T T C G T A C C T T C G A A G G T T G C T T G C T T G G T T G C T A G G T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C A T G C A T C G A A C G T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T T G G T T C C T T C C T A C C A A G C A A G C A T G C A T G G T A G G A A C C T A G C T T C G T A G G T A C G T T C G T T C C T A C C A T C C T A G G T T G C T T C G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C A A G C A T G C A A G G A T C G A T C G A A C G A A G C T T G C A A C C A T G C T T G G A A C C A T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +A C C A A G G T A C G T T G C T A C C T T C G T A G G T T G G T A C G A A G G T T G G T T G C T T G G T T C G A T C C T T G G T A C C T A C C T T G C A A C C T T G G T A G C A A G C A T C G T A G G T T G C T A C C A T C C T A C C A A G G A A C C A T G G T A C G T T G G A A C C A A C C T A G C T T C C T T C C A T C C T A G C A A G G A T C C A T C G A A G G T A G C T T G C A A G C T T C G T T G G A A G C A A G C A T G G T T G C T A G C T A G G A A C C A T G C A A G C T A G G T A G G T T G G T T G G T T G G T A G G T A G G A T G C T T G G A A G G T A G C T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A C C T A C G A A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T T C C A T G C A A C G T T G C T T C C T T G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C T T C G T T G C A A G G T T G G T T G G A A G C T T C G T A G G T A C G A A G C T T C G A A G C A A C G T A G G A A G C T A G C T A C C T A G C A T G G T T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T A G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G C A T C C T A C G T T C C A A G C T T C G A A G G A T C G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C A A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A G G A T C C T T C C A A G C T T C C T A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T C G A T G C A A G C T T G G A A G G A A C C T T C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T A C C T A G C T A C C T A G C T A G C T T G G T T G C A A G C T T G G T T G G T A G G T A C G T A G C T T G C A A C G T 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G T T C G T A G G A A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G G A A C G A A C C T A C C A A G C T A G G A A C G T A C G A T G C T A C C A A C C T T C G A A G G A T C C A T C G A T G C T T C G T T C G A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C T A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C C A A G G A A C C A A G G T T C C A A C C A T G G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G C T T C C T A C G T T C C A A G C T T C G T T C G A A G C T A C G T T G C T T C G A T C C T T C G A A C G A T C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T C C T T G G T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A C G T T C C T T C C T A G C A T C C T A G C T A G G T T C G T T G G A T G C T A C G T T G C T A C G T T C C T A G G T A C G A T G G T A G C T A C C A A G G A A G C T A C C T T C G T T G C A A G C T A C G A A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T A G G A A G G T A C C T A G C T A C C A T C G T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C A A G G T A C C A A G C A A G G A A G G A A C G A T C C T T C C T T G G T A C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T A G C T A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T A G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G C A T C C T A C G T A C C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C A A C C A T G C A A G C A T G C A T G G T A G G A T G C T A G C T T C G T A G C A A G G A T C C T T C C A A G C T T C C T A G C A T G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T G C A T G C A A G C T T G G A A G G A A C C T A C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G G T T G C A A C G T A C C T A G C T A G C A A C G T A C C T CGU_MN148 # subpop. label: 7 (internally 7) -2 2 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 2 1 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 1 1 1 2 2 2 1 2 2 2 1 2 1 2 1 2 2 1 1 1 1 1 1 2 1 2 2 1 1 2 1 2 2 2 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 1 2 2 1 1 2 2 1 2 1 2 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 1 1 1 2 1 1 2 1 1 1 2 1 1 2 1 1 1 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 1 2 2 2 2 2 2 2 2 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T C G T T C G A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A G G T A C G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G T A G C A A G C A A C C A A C G A A G C A A G G T T C C A A C C A T C G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T T G C T A C C T A G C T A G G T T C G T A C C T T G C T T G C A A G C T A C C A A G G A A G C T T C C A T C G T T G C A A C C A A C C T A C C T T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T T C C T A G G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G C T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T C C T T G C T T G G A A G G A A G C T T G G T A G C A T G C T T G C T A G C T T G G T T G C A T C G A T C G T T C G T T G C T A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C G A T G G T A G G T T G C A T C C T A C C T T C C A T C C T T C C A T C G A A G C T A C C T A G G T T G G T A G C T T G C T A C G A A G G T T G C T A G C T A G C T A G C T T G C T A G C T A G C T A G C T T G C T A C C T A G G A T G C T A C C T A G C T T G G A A C G A A G C T T C C A A C G A T G C T A G G A T G C T T G C T T G C A A C C A T C C T A C G A A C G T A G G T A G C A A C C T A C C A T G C A A G C A A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T T C G T T G C T A C G T A C C A A C G A A G G A A G C A A C C T T G C A A G C T A C C T A G C T A C G T A G C A A G C A T G G A A G G A T G G T A C G T T G C A T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C C T A G C A T G C T A G C A A C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C C A A G C A T G C A A G C A A C G A A G G A A C C A A G G T T C C A A C C A T G G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T T C G T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T A C G A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G G T A G G T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A A G C T A C G A A G C T T G C T T G C T T G G T T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A A C G A A G C T A G C T A C C T T G C A T G C A A C C A T G C A A G G T A G C A T G G T A G G A A C G A T C G A T C G T A C G A A C G T T C C T T G C A A C G T T G C T A G C T A G C T T G G T T G C A A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C G A A G G A T C C A A G G T T G C A T C G A A G G A T C G A A C C T T C C A A C C T A G C T T G C T A G G A A G C A A C G A T G C T A C C A T C C T T G C A T G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN149 # subpop. label: 7 (internally 7) -2 1 1 2 2 1 2 2 2 1 1 1 1 2 2 2 2 1 1 2 1 2 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G T A G G T T G G T T C C T T G C A T G G A A C G A A G C T T C C A A C G A A G G T A G G A T G C T T G C T T G C A A C C A T G C A A G G A A C G A A C G T T G C A T C G T A G G T A G C A A C G T T C C T T C G T T G G A T G C T T C G T T C C T T C G A A G G A A G G A A C G T T G G T T C C T T C C A T C G T T C G T T G C T A C G A A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A T C C A T G G T A C G T A G C T T C C T T G G T A G C A A C C A A G G T A C C T T G G A A C C T A G G T A G G T T C G T T G C T A G G T A C C A T C G T T C G A T G G T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T G G T T C C T T G G T A C C A A G C A T G G A T G C A A C C A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T T C G T A G C A A C C T A G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G G A T C C A T C G A A G C A A C C T A G C T T G C T T C C A T C G A T C G A A C G T A C G A A G C A T G G A A G G T A C C T T G C T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T C G T T G G A A G C T T C G T A C C T A C G A T G G T T G C T A G G A A G G T A C C A T G G T A C C T A G G T A C G T T G G A T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A G G A A G G A A G C A A G C T T G G T A G G A A C C A T G C A A G C T A G G T T G G T A G G A A G G A T C G T T C G T A G G A T G G T T C C T T G C A A C G T A G C T A G C A T G G T T G G A T G C T T G C T A C G T A G C T T C G T T C C T A G G T T G C T A G G T A G C T A C C A A G G A T G G A A C C A T C G T T G C A A C C A A C C T A G G A T G C A T C G A A G C A A G G T A C C A T G C A T G C T T C C T A C C T T G C T T G C T A G C T T C C T T G G A T G C A A G C A A C C A A G C A A G C T T G C T T G G T T G C T A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T CGU_MN150 # subpop. label: 7 (internally 7) -2 2 2 1 2 1 1 2 2 1 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 1 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 2 1 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 2 1 2 2 2 2 1 2 1 2 1 1 1 1 1 2 1 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 1 1 2 1 2 1 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 1 1 1 2 1 1 2 1 1 1 1 1 1 2 1 1 1 2 2 2 2 1 2 2 1 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 2 2 2 1 2 2 1 1 2 2 2 2 2 2 2 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 2 2 1 1 2 2 2 2 1 1 1 2 1 1 2 2 2 1 2 1 1 2 1 2 2 1 1 2 2 1 2 2 2 1 2 1 2 2 1 2 2 1 1 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C A A G C A A C C T A C C A A G G T T C G A T G C A T C G A A C G T A C G A A G C A T G G A A G G T A C C T T G C T A C G A A C C A A C C T T G C A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C A T C C A T G G T A C G A A G C T T C C T A C G T A C C A A G C T T C G T T C G A A G C T A C C T T G C T T C G A A C C T T C G T A C G A T C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A C C T A G G T T G C A A G C T A C C T A C G A T G C A T G G T A G G A T G C T T G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T T G G T A C G A A C G T A G C A T G C T A G G A A C C T T C G A T C G A A C G A T C C T T G C T A G C T T C G A A C G T A C C A T C C T T C G A A C G A A G G T A G C T A G C T T G C T A G C A T C C A T G C A T G G T T G G A T G G A A G G A A C G A A C C T T C G T A C G A A C G T T C G T T C C T A C C A T C C T A G C T A G G T T G G T T G C A A G C T A C C T A G C T A G G T T C G T A G C T A G 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C T A C G A A C G T A G G A A C G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C C T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G A T C C T A C G A A G G T A G C T T G G T T C C A T G G A T C C T A C G T A G C A A C C T A G G A A G C A A C C T A G C A A C C A A C C T T C C T T G C A A G C A T G G A A C C A T G G A A G C T A G C A T G C A A C G A A C C T T G G A A C C A A G G T A G C A A G G T A C G T T G G A A C C T A G C A T G G T T C C T T G G T A C G A T G G T T C C T A C C A A G G T A C C A A C C T T G C T T C C A A C C T T G C A T C G A A G C A T C C T T G G A A C G A T G C T A G G T A G G T T G C A T G C T A C G T T C G A A G C T A C G T T G C T T C G A T C C T T C G A T G C T T G C T A G C A A C C T A G G A T C G T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A A G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C G A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G C A T G C T A C C A T G C T T G G A A G C T A C C T A G C T A C C A A C C T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T C C T A G G T T C C T A G C T A G C A A G C T A C G T CGU_MN152 # subpop. label: 7 (internally 7) -1 2 1 2 1 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 1 2 1 2 1 2 1 2 2 2 2 1 1 2 2 2 1 1 2 2 2 2 2 2 1 2 1 2 1 2 2 1 1 2 2 1 1 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 1 1 2 1 2 1 2 2 2 2 1 1 2 2 2 1 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 2 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 2 2 1 1 2 2 1 1 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 2 2 2 2 1 2 2 2 1 1 2 1 1 2 2 1 1 2 1 2 2 2 1 1 1 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 2 2 2 2 1 2 1 2 1 2 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 2 2 1 1 1 1 1 2 1 1 1 2 2 1 2 1 2 1 1 1 2 2 1 2 1 1 2 1 2 1 1 2 1 2 2 1 2 1 2 1 1 2 1 2 2 1 1 2 1 1 1 1 2 2 2 2 1 2 2 2 1 1 2 2 1 2 1 2 1 1 2 2 2 1 2 2 2 1 2 2 1 2 1 1 1 2 2 1 1 1 2 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T G C T A G G T A G G T A C C T A G G T T G C T T G C T A G G T T C G A T G G T T G G T A G C A T G C T T C C T A G C T T G G T T G C A T G C A T G G T A G G A T G C T T C C T T C C A A C C T A G G A A G C A T G C A A C G T T G C A A C C T T C C A A C C T T G C T A G C A T C G T A G C A A G G A T C C A T C C A A G G A A G G A A C C T A G C T T C G T A C C T A G C A A G C A T G G A A G G A A C C T A C G A T G G A T C C T T G C T T G C T A G G T T G C T A G C T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G A T G C A A C G T T G G A A C C T T G G T T C C A A G G A A C G A T G C T A C C T A C G T A C C A A C G T A G G T A G G T A C C A T C C T T C G T A G C T T C G T A C G T A G G A A C G T T C G T A G G A A G C T T G C A T G C T A G C T T C G T T C C A A G G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C A T G G A A G C A T G G A A C G T A G C T T C C T A G C T A G C A A C C A T C G T A C C T T G G T A C G T T G G T A G C T A G C T A C C T T G G T A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C A T C G T A G G T A C G A A G C T A G G A T G C T A C C A A G G A A C C A A G C T A C C T A G C A T G G T T G C T T G G A A C G T A G C A T G G A T G G T T G G A T C C T A G C T A G C T T G C T A G C A A G G A A G C T T G C T A C C A T C C T T C C A T G C A A C G A A G C T A C C A T G G A A G C T A G C A T G C A A C C T A C G T T G C T T G G T T C C T T G C A T C C T T C C T A C C A T G C T T G C T A G G T A C C T T G C T A C G A A C G T A C G T A C C A A G G T A G C T T C C T T C C A T G C A A G C T T G C A T C G A A G C A T C C T T G G A A C G A T C G A T C G T A G C A A C C A A C G A A C C T T C G A T G C T A C G T T G C T T G C A T G C T T C G A T G G T T C G T A C G T A G C A A G G A T C C T A G C T T C C T T C C T A G G T A C G T T G G A T G C A A G C T T C C T A C G A T G G A T C G T A G C A T C G T T C G A A C C T T C G T A C C T A G G A A G G A T G C T T G C A T G G T T G C A T G G T T G C T A G G T A C G T T C G A A G C T A C C A T G C T T C C T T G C A T C C T A C C T A C C T T G C T T C C T A G G A T G C T T C C A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G C T T G C A A C C A T C G A T C G T A G G A A C G T T C C T T C C T A C G T T G G A A G C A T G C A T G G A T G C A A G C T T C C T T G C T A C G T T C C T T G G T T G C T A G G T A G C T A G C A A G G A A G C T T C C A T G G T T G C T T C C T A C C A A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G A T G C T T G C T A C C A T G C T T G G A A G G A A C C T T C C T A C C T A G C T A G C A T C G T T G C A A G C T T G G T T G C T A G G A A C G T A G C T A C C A A G C T T C C T A G C T A G C A A C G T A C C T +A G C T A G G T A C G T T G C T A C C T T G C T A G C T A G C T A C G T A G G T T G C T T G C T T G G T T C G A T G C A A G G T A G C A T G C T T C C T T G C T T G G T T C C T T G C A T G G T T G G T T G C A A G C A T C G T A C C A A C G T A G C A T C C A T C C T T G C A A C C T T C G T A G G T T G C T T C C A T C C T A G C A T C C A T G G T T C C T T G C A A G C T A C G A A G C T T C G T A C C A A G G A T G G A A G G T A G C T A C G T A G C A A C G T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T A C G T A C C T A G C A T C G A A C G A T G C T A G G A T G C T T C G T T G C A A G C A T G C T A C C A A C G T A C G A T G C T A C G T A C C T A G C A A G C A T G G T A G G T A C G A T C C A A C G T A C G A A G G T T C G A T G G A A G G T T G G A T C G A A C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C C T A G C A T C G A A G G T A G C A A C C A T C G T A C C T T G G T A C G T A G G A A G C A A G G T T C C T T G G T A G C A A G C T T C C A A G G T A C C T T G C T T C G T T G C A A G G T T G G T T G G T A G C A T C C T T G G T A C C A A G C A T G G A T G C A A C G T A G G A A G C T A G G T A C C T A G C A T G C A T G C T A C G A A G G T A G C A A C G T T G C A T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A T G C A T C G A A C C A A C C A A G C A T G G A A G G T A C C T T G C T A C G A A C G T A G G T T C C A A G G T A C C A T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A G C A A G C A A G C T A G G A A C G A A G C T A C C A T G G A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A A C G T A C C T T G C A T C C T A G G T A C C T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T T G G A A C G A T G C T T C C T A G G A A C G A T G C T T G C A A C G T A C G T A G G T A G G A T C G T A C G T A C G T A C C A T G G A T G C T T C C T T G C A T C C T A C C T T C C T T G C T T G G A T G G A A G G T A G C A T C G A T C G A A G G A A G G A A C C A A G G T T C C T T G G A A C C A A G C A A G C A A G G A T G G T A G G A T G C T T G G A T G G T A G G A A C G T T C C T T C C A A G C A T C C T A G C T A G C A T G G A T G C T T G C T A C C T A G C T A G G T T C G T A C G T A G C T T G C A A G C T A C C A A G G A A G C T T C C T T C G T T G C A A C G T A C C A A C C A T C G A T C G A T C C T A G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C T A C G A T G C T T G G A A C C A T C G A T C C A A C C A T C G T T G C T T C C T T C C A A G C T T G G A T G C T A G C A A C G T A G C A T G C A A G C A A C G A A G C T A C C A A G G T A C C T CGU_MN153 # subpop. label: 7 (internally 7) -2 2 1 1 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 1 1 2 1 2 2 2 1 2 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 2 1 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 2 1 2 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1 1 2 1 2 2 2 2 1 2 1 1 1 1 1 2 2 1 2 2 2 2 1 2 1 1 2 2 1 1 2 1 2 2 1 1 2 2 1 1 1 2 1 2 2 1 2 1 1 2 2 1 2 1 2 2 2 1 1 1 1 1 1 1 1 1 2 2 2 1 1 1 1 2 1 2 2 2 2 2 1 1 1 2 1 1 1 1 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 1 1 1 2 2 2 2 1 2 1 1 2 2 2 2 1 1 2 2 2 2 2 1 2 1 2 1 1 1 2 1 1 2 2 2 2 1 1 2 1 2 2 1 2 2 2 2 1 2 2 2 1 1 2 2 2 2 2 1 2 1 1 2 2 2 2 2 1 2 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 1 2 2 +A G G A T G G A T G C T T G C T A C C T A G C T A C G T T G C T T G C A T C G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G C T A G C A T C G A T G G T A C G T T C G T A C C A A C G T T C G T A G G A A G C A T G C T T C G T A G C T A C C T T C C A A C G T T G C T A C C A T C C A A C C T T C C A T G C A T C C T T G C A T C C T A C C A T C G T T C G T T G G T A G C A A G G A A G G T A C C T A G C T A C G A A C G A T G G A A G C T A G C T A G G T T G G T A G C A T G G A T G G A A C G T T G C T A C G A A C C T A G C T T C C A T G G A A G G T T G G A T G C T A G C T T G C T A C C A A C C A T C C T A C G A A C G A A G G A A C G A A G G T A G G T A G C A T C G A A G G T A C G T T G C A T C C T A G C T T C C T A C C T A G G A A C C T T C G T T C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G T A G G A A C C T A C C T A G G A A G C A A G C T A G C A T G G T A C C A T G C T A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A A G C T T C C A A C C T A C G T A G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T T C C A A G C T T C G T A C C A A C C A A G G A A C C A A G G T T C C A A C C A T G G T T C C T A C G A A G G T A G C T T C G T T G C T T C G A T C C T A G C T A G G T T G C T T G C A A G C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G C A T C C T A C G T T C C A A G C T T C G A A G G A T G G T A C C A T G C T T C G A A C C T T G G A T C G T T G C A A C G A T C C T A G G T T G C A A C C T T C G A A C C A T G G A A G G T T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T C G A A C C T T C C T A G C T A C G T A G G A T G C T A G C A A G G T A C C T A G G T A G C T A G G T A C G T T G G A T G C A T G C T T G C T A C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G G T A G G T A C C T T G C T A G C T A G C A A C G T A C C T +A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G G A A G C A T G G T A C C A A G G A A G C T T G G A A C G T T G C A A G C T T C C A A G C T T C C A T G C A T C C T A G C T T C C A T C C A T C G A A G G A T G C T A C G A A G C T T C G T T G G T A G C A A G G T A G G A A G G A T C C T A G G A A C G T T G G A A G C T A C G T A G G T T C G A A G C A A G G A A G G T A C C T A G C A A G C A A C C A A G G T T G C T A C G A A G C T A G G A T G C A A C C T T G C A A C G T T C C A A C G A A C G T A C G A T G C T A C C A A G G T A C C A A G C A A G G A A G G A A C G A T C C T T C C T T G G T A C G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C A A G G T A G G A T G G T A C G T A G G T A C G T A G C A A G G A T C C T A G C A A G G T T C G A T G C A A G G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A C C A A G G A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T T G G A T G G T A C G T A G C A A G C T A C C T A G C A T G C A T C C T T C C T T G C T A G C A T G G A A C C T A C G A A G C T A G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T A G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C T T G C A T G G T T G C A A C C T A C G T A G C T A G G T T G C T T C G A T C C A T C G A A G C A A G C T A G C A A C C T T G C T T G C T A C C A T G C A A G C A T C C A T G G A T G C A A C G A A G G T T G G T A C G A A G G A T C C T T C C A A G C T T C C T A G C A A G G T T C G T T C C A A G C A T C C T A G C T T C G A A C C T A G G T T C G A T G C A A G C T T G G A A G G A A C C T T C C T T C G T T G C A A C G T A C C A A G C A T C G A T C G A A G C A T C G T T G C T A G G A T G G A T C C T A C G A A G G T T G C T A C G A A G C T T G G A A G C T T C C T A G C A A C C A T C C A T G C T A C G T T G C A A G C T T G C T T C C T A G C A A C G T A G C T T G C A A C G T A C C T A G C T A G C A A C G T A C C T CGU_MN154 # subpop. label: 7 (internally 7) -2 1 1 1 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 1 1 2 1 2 2 2 1 2 2 1 2 1 1 1 1 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 2 1 1 2 1 1 1 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 1 1 2 2 2 1 1 2 2 2 1 1 1 2 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 2 1 2 2 2 2 1 2 1 1 1 2 1 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 2 1 2 2 1 1 1 2 2 2 1 2 1 1 1 1 2 1 1 1 2 1 2 1 2 2 2 2 1 2 2 1 1 2 2 1 2 2 1 2 2 2 2 2 2 2 1 1 1 2 1 1 1 1 2 1 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 2 1 1 2 1 1 1 2 1 1 2 1 1 2 1 2 2 2 2 1 1 1 2 1 2 2 2 2 1 2 1 2 2 2 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 2 1 1 2 1 2 1 1 1 2 1 1 2 2 1 1 1 1 2 2 2 2 1 2 1 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 1 2 1 1 1 1 1 2 2 1 1 2 2 1 2 1 2 2 1 1 2 2 1 1 2 2 2 1 1 2 1 1 2 2 1 1 2 1 2 1 1 2 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 2 2 2 2 1 1 1 1 2 1 2 2 2 1 2 1 2 2 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A G G A T G G A T G G T A G G A A C G T T C C T A C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G G A T C C A T C C A A G C A T C G T T G C T A G C A T G C T A G C T A C G T A G G A T G C T A C C T T G C A T G G A A G C A T C C T T G C T A C C A A C G T T C C T T C G T T G C A A G C T T G C T T C C A A G C A A C G T A G G T A C C A A G C A A C C T A G G T A G G T A G C A A C G T CGU_MN155 # subpop. label: 7 (internally 7) -2 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 1 2 2 1 1 2 2 2 2 1 1 1 2 2 2 1 2 1 2 1 1 2 2 1 2 1 2 1 2 2 1 2 1 1 2 1 2 1 2 2 2 2 2 2 2 1 2 1 2 2 2 2 2 1 1 2 2 1 2 1 2 1 2 1 2 1 2 1 1 2 2 2 1 1 2 1 2 2 1 1 2 2 2 1 1 1 2 1 1 1 1 2 2 1 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 2 2 1 2 1 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 1 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 1 1 1 2 2 2 2 1 1 1 2 1 2 2 1 2 2 1 1 1 2 1 1 2 2 1 1 1 2 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G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A T G G T A C G T A G C T T C C T A G G T A C C T T G G A A G G T A G C T T G G T A C C T T G G T T G C A A C C A T G G A A G G A T G G A A G C T A C C A T G G T A C C T T G C T A C G T T G C T T C G A A G G T T G G A A G C T T C G T T G G T A C G A A G C T A G C A A G C A A C G A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T A C G T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G C T T C C A T C C A A G C A A C C T A G C T T G G T T C G A A G C T A C G A T C G T A G C A A G C T T G C T A G C A A C C A T G G T T C G A T G G T A C C T T C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T G C A A G C T T C C T T G G T A C C A A G C T A C C T A C G A A C C A T G C T A C G A A G C A T G G T A C G T T G C T T C G A T C C T T G G A A C G A A G C T A G G A T C C T A G G A T C C T A C C T T G C A T C C A T G G T A C G T T G G T T G C A A C C A A G G T A G C A T G G A T G G T A G G A T G C T A C G A T C C T T C G T A C C T A G C T T G G A T G C T T G C T T G G T A C C T A G G T A C C T A G G T A C G T T C C T A G C T A G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C A T C G A A C G A A G G T A G C T A G C T T G C A T G C A A C C A T G C A T C C T A G G A T G G T A C G A A G C A T G G A A C C A A G G T A C G T T C C T T G C A A C G T T G C T A G C T A G C T T G G T T G C A T G C T A C C T A G C T A G G T T C G T A C C T T G C T T G C T A G C T A G G A A G G A T C C T T C C A T C G T T G C A A C C A A C C A A G C T T C C A T C C A T G C T T G G A T G G T A C C A A G C T T C G A A C G A T G C T T C C A A C C T T G C T A G G A A G C A A C C T T C C A A C C A T C C T T G C T T C G T T G C A A G C T T G G T T G C T T G C T A C C T A G C A A C C T A G G A A C C T A G G T A G G T A G C T A G C A +A G G T A G G A T G C T T C C T A C C T T C G A A G G T A G G T A C C A A G G A T G C T T G C T A G G T T C G A A C C T A G G T A C C A T G C T T G C T T G C A T G G T A G C A T C C T T C G A A G G A T G G T A C C A T C G T A C C T A G G A A C C A T G G A T C G A T G C A A G C T T C C T T G G T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C C A T G G T T C C A A G C T A C C A A C G A A G G T A G C A A G C T A G G A A C G T A C C T A G C T T G C A A G G T T G G T A C C T T C C T A G G T A C G T A G C T T G G A T G G T A G G T A C C A A C G A T G C T A G G A T G G T T G C T T G C A A G C A T G C T A C C A A C G T T G G T A G C A A C C T A C G A T G C A A G C A A G G A A C G T A C G A T C C T A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A C G T A C G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G A T G G A T C C A A C G A A G G A A C C A A G G T T C C A A C C A A G G T T G C T A C G A A G G T A G C T T G G T T G C A T G G A T C C T A C C T A G C T T G C T A G C A A G C T A C C A T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T A C G A A G G T A C C T A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G C T A G G T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A C C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A A G C T A C G A A G C T T G C T T G C T T G G A T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A A C G A A G C T A C C T A C C T T G C A T G C A A C C A T G C A A G G T T G C A T G G T A G G A A C G A T C G T T C G T A C G A A C G T T G C T T C C A A G C A T G C T A C C T A G C A T C C T T G C T T G C T A C G T T G C T A C G T T C C T T G G T T G C T T C G T A G C T A C C A A G G A A C C A A C C A T C G T T G C A A C C T A C C A A C G A T C C A T C C A T G C T T G G A T G C A A C C A T G G A T C G T A C G A A G G T T G C T A C G T T G C T T G G A A C C A T C C T T G C T A C C T A G C T T G C T T C C T T C C A A G C T T G C T T C C A A G G A T C G A T G C T A G C T A G G A A C C T A G G T T G C A A C C A A C G T CGU_MN158 # subpop. label: 7 (internally 7) -2 1 2 1 2 2 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 1 1 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A G G A T G C A A G C T A G C T A C C T T C C A A G G T A G C T A G G T T G G T A G G T T G G T A G G T A G C A T C C T T G C A A C G A A G G T T G C T A C G A T G G T T G G A T G C T T G G T T G C A A C C T T G C A A C C T A G C A T C G A A G C T T G G T A G G T A G C A A C C T T G G A A C G A A C G A T C C A A C G T A G G T T C G A A G G A T C C A T C G A T G C T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A T G C A T G G T A C G T A G C T T C G A A G G T A G C A T C C A A G G T A C C T T G G A A G C A A G G A A G C T A G C T A G G A A G G T A C C A T C G T T C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G G T T C C A A G G A A G G T T C G A T G C T T G C A T C G T T C C T A C G A A G G T A G C T A C G A T G C T T C G A T G C T T C G T A G G T A C G T A C G A T G G T A C C A T G G T A G C T T C C T T G G T T G G T T G C A A G C A A G C A T C G A A G C T T G C A T C C A A C C A A G G T T G C T T G G T T C C A A C C A T C G A A C G T A C C A T C C T T G G A T G G T A C C T A C G T A G C A A C C A A G G T T G G T A G G T A G G T T G C T T G C T T C C A A C C T A G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G A A C G A A G C T A C G T T G C A A C G A T C C T A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C T T G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G A A C G A T G C T T G G A T G G A T G C A T G G T A G C T A G G T A C G T T G G A T G C A A G C A T G C T T C C T T G C A T G G T A C C A A G C T A C G T T G C A T C G T A C C T A G G A A C C T A C C T T G G A A C C T A G C T A G C T T G G T A G G T A C C A A C G T T C C T T G C A T G G A A G G A T C C T A G G A A C C T A G C A A C C A T C C T T G C A T G C A T G C A A G G T A C G A T G C T A G C A A G C T A C G T T G G A A G C T T C C A T C C A A G G T A G C A A G C A T G C A A G G A A C G A A C C T T C G A A G C T A C C T A C C T A C G T A C C A T C C A T G C T T G G A T C G A T G G T T C G T T C C T A C G T A G C T A C C T A C C A T G C T T G G A A G C A T C C T T G C T A C C A A C C T A C C T T C C T T C C A A G C T T G C T T G C T A G C A A C G T A G G T A G C A T G C A A C G A A G C T A C C A A G G T A C C T +A G G T A G G A T G C T A G G A T G C T A G C T A G G T T G G T A C C T A C G T A G G A A G C A A C G A A C G A A C G T T G G T A G C A T G C A T C C T A G C T T G G T A G C T T C C T T G G T T G G T T G C A A G C A T C G T A G C T A G G A T G C A T G C A A C G T T G C A A G C T T C C T T G G T T G C T T G C A T C C T A G C A T C C A T C C T T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G C A A C G T T C C T A G C T A G C T A G G T T G C T A G C T T C C A T G C T A C C T T C C A T G G A A C G T A G G T A G C A T G G A A G G A A G G T T G G T T G C T T G C A A C C A T C C A T C C A A G G T T G G T A C G T T C G T T G C T A G C A A G C A T G G T A G G T A C G A T C C A A C G T A G C T T C C T A C C A T C G A A C G T T C G T A C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G A T G G A A C C A T C C T A G C T A C C A A C G A T G C A T C G T T C C A T G C T A C G T T G G A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C A A C G A A C G T T G G A T C C A T G G A A G C T A C G A T G G T A C C T T G C A T G G T T G G A A G G T T G G T T G C T A C C A A C G T A G G T A C C A A G G A T G G A T G C A T C C T A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G A T G C T T G G T T G C T T G G A T C C T T C C T A G G T A C G T A G C T T C C T A G G T T G C A T G C A T C C T T G G A A G G T A G C A T G G T A C C A T G G A A G C T A G C A T C C A A C C A A C C T T C C T T G G T T C C A T G G T A C G A A C G A T C G A T G G A T G G A T C C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T A C C T T G G T A C G A A G C T T C C T A C C A A G C A A G C T A G G T T C G A A C G T A C C A T G C A T C G A A C C T A C G A T G C T T G C T A C G A T C C T A G G A T G C T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T T C G T A G C A T G G A T C G T A G G A T C G T T C G A A C C T T C G T T G C T T C G T A G G T T G C A T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T CGU_MN159 # subpop. label: 7 (internally 7) -1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 2 2 2 2 2 2 2 1 2 2 2 2 2 1 1 2 1 1 1 1 1 2 1 2 2 1 2 1 2 2 2 2 1 2 2 2 1 1 1 1 2 2 2 2 2 1 2 2 2 2 2 2 1 1 1 2 2 2 2 2 2 2 2 1 1 2 1 2 1 1 1 2 2 1 1 1 1 1 2 2 2 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 1 1 1 1 1 1 2 1 2 2 2 2 1 2 2 2 1 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 2 2 1 1 2 1 2 2 1 2 2 1 2 2 2 2 2 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 1 2 2 2 1 2 2 2 1 1 1 2 2 2 1 2 1 1 1 2 1 2 2 2 2 2 2 1 2 1 2 1 1 1 2 2 1 2 2 2 1 2 1 2 2 2 2 1 2 2 1 2 2 2 1 1 2 1 1 2 2 1 2 1 2 1 2 2 1 2 1 2 1 2 2 1 1 2 2 1 1 1 2 2 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1 2 2 2 2 2 2 1 1 2 +T G C T A C G T A C G T T G C T A C C T T C G A A G G A A C G T T C C T A G G A T G C T T G C T T G G A A C G T A G C T A G G T A G C T T C C A T C G A A C C T T G G T A G C A A G C A T C G T A G C T T G C T A G C A T C C T A G C T A G G A A C C A T C C T T C G A T G C T A G C T T C G T T G G T T G C T T C C A T C C T A G C T T C C A T C C A T C G A T G G T A G C A A G C A A G G T T G G T A G C T T G C A A G C T A G G A T G C A A C C T A G G A A C C T T G C A A G C T A G G T A G G T T G G T A G G T T G G T A G G T A G G A T G C T T G G A T G G T A G C T A C C A A C G A A G G T A G G T T G C T A C C T T G C T T C C A T G C A A C C A A G G T T G G T A C G T A C G A A G G A T G G A A G C A T G G T A G G T A C G A T C C A A C G T A G C T T C C T A C C A T C G A A C G T T C G T A C G T T G C T T G C A T G C A T G C A T G G A A C C A A C G A A G G A T C C T T C G A T G G A A C C A T C C T A G C T A C C A A C G A T G C A T C G T T C C A T G C T A C G T T G G A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C A A C G A A C G T T G G A T C C A T G G A T C G T T C G A T G G T A C C A T G G A T C G T A G C A A G G T A C C T T G G T T G G T A C G T A G G A T C C T A G C T T G C A T G G T A C C A A G G A A G C A A C G A T G C T T G C T T G C A T C C T A C G A A G G A T G C T T G G A T G C T T C G A T G C T A C C T A G G T A C G T A G C A A G C A A C C T T G C A T C C A T C C T T C C A T G G T T G C A A C G T T C C A T C G A A G G T T G C A T C G A A G C A A G C T A G C A A C C T T C C T A G C A T C C T T C G A T C G A T G C A T G G T A G C A A G C T T G C T A G C A A C C T A C G T A C C A A G G T A C G T T G C T T G C T T C C A A C C T T G C A T C G A A G C A T C C A T G G T A C G A A G G T T C C T A C G T T G C A A C C T A G G T A C G A A G C T A C G T T G C A A C G A T C C T A C G A T G G A A G C A T C G A A C C A A G G A A C G T A C C T T G C A T C C A T G G A A C G T A G G T T G C A A C C T T C C T T G G A T C C T T C C T A G G A T G C A A G G A T C C T T C C T A G C T A C G T A G G T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A G C T A G C T A C C T T C C A T G C A T G C A T C C A A C C T T G C T T G C A T G G T T G C T T C C T T C C A T C G T T G G A A G C T T C C A A G C T A C C T T C G A A G C A T G C A T G C T T G G A T G G A T G C A A C G A A G G T T G G A A C G A T C C A T C C T T C G T A C G T A C G T T G C T A G C T T G C A A G C T T G C T T C C T T G C T T C G T T G G A T C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C C T T G C A T G C T A C C A A C G A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A G G T A G C T T G C T A C C T T G C T T G G A A G C T T C C T A G C T T C C A A C C T A C C T A G G T T G C A A G C T T G C T T G C T A G C A T C C T A G C T T C C T A G G T A C C T A G G T A G G T A G C T A G G T +A C G T A G G T A C G T T G C T A G C T T G C T A G G T A G G T A C G A A G G T T G C T T G C T T G G T T C G A T C C T A C C A T G C T A C C T T G C A A C C T T G G T T G C A T C G A T G G A A C G A T G G T T C C T T G C T A C C A A C G A A G C T T G G A A C G T T G C A A G C T T C C T T G G T T G G T T G C A T C C T A G C A T C C A A C C T T C C T T G G T A G C T A G C A T C G T T C C A A G C T A C C A A G C A A G C T T G C T A C C T A C C A A C G T T C C T A G C T A G C T A G G T T G C T A G C T T C C A T G C T A C C A T C C A T G G A A C G T A G G T A G C A T G G A A G G A A G G T T G G T T G C T T G C A A C C A T C C A T C C A A G C T A C G A A G C T T G G T A G G T A G C A A C C T A C C T T C G A A C G A T C C A A C G T A G C T T C G A A G C A T G G A A C G T A C G T A C G A A G C T T G C A T G C T A G C T T C G T A G C A A G G A A G C A A G G A A G G T A G G T A G C T A C C T A G G A A G C A A G C T A G G A T G G T A C C A T G G T A C G A A G G A T C C T A G C T A G G T T G G A A C G T A C C T T G G T A C C T A G C A A G C T A G C T A C C T T G G A A G C A A G G T T C G A T G G T A C C T T G C T A C G T T G C A A C G A A G G T T G G T T C C T T C C T T C G T A C C A A G G A T G C A T G G A T C C A A G G A A G G T T C G A T G C T T G C A T C G T T C C T A C G T A G G A A G C T T G G T T G C A T C G A T C C T T C G T A G G T A C G T T G C T T C C A T G C A T C G T A C C A T C C T T C C T T G C A A C C A A G C A A C C T A C G T A G C T A G C A T C G A A G C A A G C T T C C T T G C T T G G T T C G A A C C T A C G T A C C A T C C T T G G A T G C T T C C A A C G T A C G A A C C A A C G A A C G A A G G T A C C A A C C A A G C A T G C T A G C T A C G T T C G T A G G A A C C A T G G T A C G A T G G T A C C T A G G T A G C A T G C T T C G A A G C A A G G T A G G A T G C A T C G A T C C T A C G A T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C A T C G T A C C A T G G T A G C A A G G T T C C T A C G A T G C A T G G T A G G A T G C T A G G A A C C T T C C T A G C T T C G T A G G T T G C T A C C T A G G T A C C A T G G T T G C T A G G A A C G T T C C T A G C T A G C A T G G T A C C T T G C A T C G A A C G A T C C T A G C T T G C A T G G A T G C T A C C A T C G A T C G A A G G A A G C T A G C A A G C T T G C T T G G A A C C A T G C A A G C A T G C A T G G A A C G A A C C T A C C T T C G T A C G A A C G T T G C T T C C T A G C A T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T T C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G T A C G T A C C A A C C T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T A G C A A G C A T C G T A G G T A G G T A G C T A C G T CGU_MN160 # subpop. label: 7 (internally 7) -2 1 2 2 2 1 1 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 2 1 1 2 2 1 1 2 2 2 2 1 2 1 2 2 1 2 2 2 1 2 2 1 2 2 2 1 2 2 2 1 2 1 2 1 1 2 2 1 1 2 2 1 1 1 2 2 2 1 2 1 2 1 2 2 1 2 1 1 1 1 2 2 1 1 2 2 2 1 1 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T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T G G T A G G A T G C T A G G A A C C T T C G T T G C T A C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G T A C G T A C C T A G C T A G C T T G G T A C C A T G C A T C C T A C C A A C C T A C G T A G C A T G G T T G C T A C G A T C C T T G G A A G C A A G C T A G C A A G C A A C C T T G G A A C G A T G C A A G C T T G G T T G G T A G G A A G G A A G C T T G G T A C G A A C G T T G C T T C C T A G G T A G C T A G C A A G G A T C G T T C C A T G C T A C C T A G C T A G G A A C C T A C G T T G G T A G C A A G C A T C C A A G G T T C C A T G C A T G G T T G C A A G C T A C G A T G C A T G C A T C C A A G C A T C G A T C G T A G G A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G G A A C C T T G C T A C C A A C C T T G C T A C G T T G C A A G C T T G C T T C C T A G C T A C G T A G C T A C G A A G G A A C C T A G C T A G C A A C G T A C C T CGU_MN161 # subpop. label: 7 (internally 7) -1 2 1 2 2 2 1 1 1 2 2 2 2 2 1 1 1 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 2 2 1 1 2 2 2 1 1 2 2 2 1 2 1 1 1 2 1 1 1 1 1 2 2 2 1 2 1 1 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 1 2 1 2 2 1 1 1 1 1 1 2 1 1 2 1 1 1 1 2 2 1 2 2 2 1 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 1 1 1 1 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 1 1 1 1 1 2 2 1 1 1 2 2 2 2 1 1 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 2 1 2 2 1 2 2 2 1 1 2 2 1 1 1 1 2 2 2 2 1 1 2 1 1 2 1 2 1 1 2 2 2 2 2 1 1 2 2 2 1 2 1 1 1 1 2 2 2 1 2 2 1 1 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 1 2 1 2 2 2 2 2 2 1 1 2 1 1 2 1 1 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 2 1 2 2 2 2 1 2 1 2 1 2 1 1 1 2 2 2 1 1 1 2 1 1 1 2 2 1 1 2 1 1 1 2 2 1 2 2 2 1 2 2 2 2 1 1 1 1 1 2 2 1 2 2 1 1 2 1 2 2 1 1 1 2 2 2 2 2 2 1 1 2 2 2 1 2 2 2 2 1 1 2 1 2 2 1 1 1 2 1 1 1 2 1 2 2 2 1 2 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C T A G C T A C C T A G C A A G G T T G C T A G G A A G G T A G C A T C G T T G C A T G G A T C C T A C C T A G G T A C C T A G G A A G C T A C C T T G C A T C C A T C C T A C G T T C G A A C G A A G C T A C C A T G G A A G G T T C C A T C C A A G C A A C C T A C C A A G G T T C G A A G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A T G C T T C G A T C G T A C C T T C C A A G G T A C C T T C C T A C C A T G C T A G G T A G C A A G G A A G C T T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T C C T T G C A T C C A T G G T A C G T A G G T T G C A A G C T A C C A A G C A A C G A T C G T A G G A T G C T A G G A A C C T T C G T T G C T T C G T A G C T T G C T T G G T T G G A T G C A T C C T T G C T A G G A A C G T T C C T A C C T T G C A A G G A A C C T T G C A T C G A A C G A A C C T A C G T A G C T A C G T A C G T A C G A T C C A T G G A T G G A A G 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C A T G C A T C C T T G G A T G G T A G G A A C G T T C C A T G G A A G C T A G C A T C C A A C C A A G C T T C C T A G G T T C G A T C G T A C G A A C C A T G C A A G C A T C C A A G C A A G C T T G C T A C G A A C G T A C C A A C G A A G G T A C C T T C C T A C C A T G G T A G G T A G C A T C G A A G C T T C C A T G G T A C G A T G G T A G G T A C G T A G C A A C C T A C G T T C C A A G G T A C C A A G C A T C G A T C G A A C G T T G C T T G C T A G G A T C C T A G G A T C C T A G C T T G C A T C C T A G G T A C G T A G G T A G C A A G C T A C C A A G G A A C C T T G G T A G G A T G C T A C G A T C C T T C G T A G C T A C G A A C G A T G C T A C G A T G G T A C C T A G G T T G C T T G G T A C G T T C G T A G C A T G C T A G G A A C C A T G C A T C G A A C G A T C C T A C G T T G G A T C G T T G G T T C C T T C G A T G G A A G G A A G C T A G C A A G C T T G G T T G G T A C C A A C G T T C C T T G C A T G C T T G C A A C G A T G G A T C G T A C G A A C C T T C C T T C C T A C G T T G G A A G G T T G C T T G G A A G G A T G C A A G G T T C C A A G C T T G C T A G C A A G C T T C G T A G C A T G C A A G G A A C C T A C C T T C G T T G C T T C C A A C C T A C C A T G C A T C C A A G C A T C G A T C G T A G G A T G G A T C G A A C G A T G C T T G C A A C C T T G C T A G G A A C C A T C C A T G C A A C C A A G C T T G C T T C C T T G C T A G C T T G C T T C C T A G C A T C C T A G C T A G C A A G C A A C C A A G C T A C C A A G G T A C C T CGU_MN196 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 1 2 1 2 2 2 2 1 2 1 2 2 1 2 2 1 2 1 2 2 1 2 1 2 1 1 2 2 1 2 2 1 1 2 1 2 1 2 1 2 1 2 1 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 2 2 2 1 1 2 1 1 1 1 1 2 1 2 2 1 2 2 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 2 2 2 1 1 2 1 1 2 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 1 2 2 1 2 1 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 2 1 2 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T C G A A C C T T C G A A C G T T G C T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G T A C G T A C C T A G C A A G C T A C C T A G C T T C G A T C C T A G G A T G C T A C G A T C C T T C G A T C C T A G G A A C G A T G C T A C G T T G G T A C C T A G G T T G C T T G G T A C G T T G G A T C C T A C C A A C C T T C C T T G C A T C C T A C C A A C C T T G C T A G C T T G G T T G C T A C C A T C C T A G C A A G G A A G C T T C C A A G C T T G G T A G C A A C G A T G C A A G C A A G C A A G G T A G G A T G C A T G C T T C G T T C G T A G C T T C C T T C C T A G G T A G C T A G C T A G C T T C G T T G G A A G C T T C C T A G G T T C G T T C C T A G G T A G C T T C G T A G C A T G C A A G G A A C G A A C G A T C G T T G G T A G C A A C C T A C C A T C C A T C C A T G C T A G G A T G C T A C G A T G G A T C G A A C G A T G C T T G C T A C C A T G C T T G G A A G G A T C G A T C G A A C C A A C C T A G C T T C G T T C C T A G C T T G C T T G C T A G C A A C C T A G G T A G C A A G C A T C G A A G C T A C C A A G G T A C C T +A C C T A G G T A C G T T G C T A G C A T C C T A G C T A G C A A C C A A G G A T G C T T G C A A C G A T G G A T G C T T G G T A G C A T C C A A C G T A C C T A G C T A G C A A G C A T C G T A G C T T G G T T C C T T G C T A C C A A G C A A C C A T G C T T C G A T G C A A G C T T C G T T G C T T G C T A C C A T C C T A G C T T C C A T C C T T C C A T G G A A G C T A C G T A G G T T G G T A G C T T G C A A G C T A G G A T G C T A C C T A G C T A C C T T G C A A G C T A G C A A G G T T G G T A G C T A G G T T G C T A C C T A G C T A G G A A C C A A G C T T C C A A C G A A G C T A G G A T G C T T G G T T G C A A G C A T G C T A C G A A C G T A C G A T G C T T C G T A G G T A G G A A C C T A G G A A C G A A C G A T G C A A G C A T G C T A C G A A C G A T C C A A C C A T G G T T C C T T C C T T G C A T G G T A G C T T C C T A C G A A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A 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A C G A T C G T T C G T T G C A A G G A A C C T T C G T A C C T A C G A T G G T T G C T A G G A A C G T T C C A T C C T T G C T A G G A A C G A A C C T A C C T T G C T A G C T A C C A T G C A T G G T A C C A A G C T A C G T T G C A A G G A T G C T A C C A T C C A T G G A A G G A A G C T A C C T T G C A A C C T A G C T A C C A T G C A T G G T T G G A T G G T A G G A A G G A A C G A T C G T A G G A A G G A T C C T T G C T A C G T T C G A A G G T T G C T T G G A A G G A T G C A A C G T T C C A A G C T T G C T A G C A A C G T T G C A A G C T A G C A A G G A T G G A A C C A T C G T T G C A A C G A A C C A A C G A T C C A T C G A T G C T A G G A T G C A A C G T T G G A T C C T A C C A T C G A T G C T A C C T A G C A T C C A A G C T A C C T T C C T A C C T A G C T A G C A T C G T T G C A A G C T T G G T T G C T A G C T A C C T A G C A A G G T A C C T T G C T A G C T A G C A A C G T A C C T CGU_MN197 # subpop. label: 7 (internally 7) -1 2 2 1 2 1 1 2 2 1 2 2 2 2 1 1 1 2 1 1 2 1 1 1 2 2 1 2 2 1 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G A T G C T T C G A T C G T A G C A A G C T T G C T A G C A A C C A A C G T T C G A A G G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G C T T G C A A G C A A G C A T C C A T G G T A C G A T G G T A C C T A G C A A C C A T G C T T C G T A G C A A G G T A C C A T G C A T C G A T C C T A C G A T G G A A G C A T C G A A C C A A G G A A C G T A C C T A G C A T C C A T G G T A C G A T G G T A G C A A C C T T C C T T G G A T C C A T C G T A G G A T C G T T G G A T C C T T C C A A G C A A G G A A C G A T G C T A C C A A C G T A C C A T C C A T G C T A G G A A C G T T C C T A G C T A G C A T G G T A C C A T G C A T C G A A C G A T C C T A G C T T G C A T G G A T G C T A C C A T C C T T C G T A G G A A G C T A G C A A G C T T G C T T G C A T C G T T G C A A G G T T G G A T G C T T G C A A C C T A C C T T G G T A C G A A C G T T G C T T C G T A C G T A C G T T G C T A G C T T G C A A G C T T G C T T C C T T G C T T C G T T G G A A C C T T G C T A G G A A G C A T G C A A G G A A G C T T C C A T C C T T G C A T G C T A C C A A G C A T C G A T C G A A G C T T G G A T G C T A C C A A G C T A G C T A C G T A G C A A C C T A G C T T G C T A G G A A G C A A C G T A C C T T C C A T C G T A G C T T G G T T G C A A G C T T G G T T G C T A G C T A C G T A G C T T G C A A G C A A C C T A G C T A C C A A C C T A G C A CGU_MN198 # subpop. label: 7 (internally 7) -2 1 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 2 2 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 2 2 1 1 1 2 2 1 1 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 1 2 2 2 2 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 1 2 1 2 1 1 2 2 1 1 1 2 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 1 1 1 2 1 2 1 2 1 2 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 1 1 1 1 2 1 2 2 2 2 2 2 2 2 1 2 1 2 1 1 2 2 2 2 1 2 1 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 1 2 1 1 2 2 1 2 2 2 1 2 1 1 1 1 2 1 1 1 1 2 2 2 2 1 1 1 2 2 2 2 1 2 2 2 1 2 2 1 2 2 2 1 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C T A C C A T G C T A G C T A G C A T C C A A G C A T C C T T G C A A C C A A G C T A C C A A C G A A C C A T G C T T C G A A G C A A G G T A C C A T G C A T C G A T C C T A G G A A G G A A C G T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G A T G C A T G G A A C C T T C C T A G C T T C G T A G G T T G C A T G G T T G G T A C C A T C C T T G C T A G G T A C G T T C C T T G C A T G C A T G G T A C C T T C G A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C T T C G A T C G A A G G T A C C T A G C T T C C T T G G A A C C A T G C A A G G T T G C A T G G T A G G A A G C A A G C A T G G A A G C T A G C T T C C T T C C T A C G T T G C A A C G A T G G T T C G T T G G T T G C T A C G T A G C T A G G T T C G T T G G T A G C T T G C A A G C T A C C A A G G A A G C T A C C A T G G A T G C A A C C A A C G T A C G A T C C A T C C A A G C A T G C T A C C T A C G A A G G A T C G A A C G A A G G T T G C T A C G A T G C T T G G A A G C A A C C T A G C T A G C A T C G T T G C T A C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A C C A A G C A T C C T A G C T A C C A A C C T A G C A CGU_MN200 # subpop. label: 7 (internally 7) -2 2 2 2 2 2 1 2 1 1 1 2 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 2 2 1 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 2 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 2 1 2 1 2 2 1 2 1 2 1 2 1 2 1 2 1 1 2 2 2 1 1 2 2 2 2 1 2 1 2 1 1 1 2 2 2 1 1 1 2 2 1 1 1 1 1 2 2 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 2 1 1 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 2 1 2 2 2 1 1 2 2 2 1 1 1 2 2 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 1 2 1 1 2 2 1 1 2 2 2 1 1 1 1 2 2 2 2 1 2 1 2 1 2 1 2 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 2 2 1 1 1 1 1 2 1 1 1 2 2 1 2 1 2 1 2 1 2 2 1 2 2 1 1 2 2 1 1 2 1 2 1 1 1 2 2 1 1 2 1 2 2 1 2 1 2 1 2 2 1 1 2 2 1 2 2 2 1 1 1 1 2 2 1 2 2 2 2 2 1 2 1 1 1 1 1 2 1 1 1 1 2 2 1 1 1 1 2 2 2 1 1 2 1 1 2 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T G G T A C C T A G G A T G C T T G C T T G G A A G G A A C C T A G G T A G C A T G C A T C C T A G C T A G G T A C C A A C C T T G G T T G G T T G G A A G C A T G C T A C C A A C G A A G C A T C C T T C G A T G C A A G C T T C C T T G C T T G C A T G C A T C C T A G C A T G C A T G G T T C C T T C G A A G C T A C C A A G C T T G G T A G G A A G C A T C C T A G G T A G C T A G C T A C C A A C C T T G G A A C G T A C G T A G G A T C C T A G G T T G G T T G G T A C G T T G C T A C G T A C C T A G C A T C G A A C G A A G G T T G G T T G C A A G G A A G G A A C C A T C C T T C C A A G G T T G G T A C G T A C C T A C G A T G C A A G C T A C C A T C G A A C G A T G C A T C G T A G G A A C G T A C G T A G G A A C G T T G C T T C C T T C C T T G C A T G G T A G C T T C C T A C C T T C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G G A T G G T A C G T A G C T T C C T A G G T A G C A A C G T A G G T A G C A T G G A A G C T A G G A A C G A A C C A T G G A A G G T A C C A T C G T A C C T A G G T A C C T T G C A T C G T A G C A T G G T A C C T T G G T A G C T T C G T A G G T A C C A A G C A T G G A A C C A A C C A A C G A A C C T A G C T A C C T A G C A A G G T T G C T A G G A A G G T A G C A A C G A T C C A T C G T T G C T T G G A A C C A T G C T T G G A A G C T A G C T T G C A T G C A T C G T T C G T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A A G C T T C G A T C G T A G C A A G C A T C C T A G C A A C C A T G C T T C G A T C G T A C C T T C G A A G G T A C C T A C C T A C C A T G G T A G G T T G C A T C G A A G C A T C C T T G C A A C C A A G C T A G C T A C G A A C C A T G C T A C G A A G C T A G C T A C C A T G C A T C G A A C C T T C G A T G G A A C G A A G G A T C C T A G G A T C G T T G C T A G C A T C C A T G G T A C G T A G G T A G C A A G C T A C C T A C C A T G G A T C G T A G G A T G C T T G G A T C C T T C G T A G C T A C G T A G G T T G C T T G G T T G G A 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T C C T T C G T A G C A A G C T A G C T A G C T T C G A T G C T A C G A T G C A A G G T T G G A T G C T T G C A A C C A T C G A T C G T T C G T T C G T T C C T T C C T A C G T T C G A A G G T T G G A A G C T A G C A A G C T A C C T A G G A A G G T T G G A A C C T T G C T A G C A A G C T T G C A A G C A A C G A A C C T T C G T A C C T A G C A T C C T A C C A T G G A A G G A A G C T T G G A T G C T A G C A T G C T A C G A A C G A A G G T A C C A A G C T T G C T T G G A T G C A T C G T T G C A A C C T A G C T A G C A T C C T T G C A A G C T T G C T T C C T A G C A A C G T A G C T A C C A A G C A T G C T A G G T A G G A A G G T A C C T CGU_MN286 # subpop. label: 7 (internally 7) -2 2 1 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 1 2 1 1 2 2 2 1 2 1 2 2 2 1 1 2 2 1 2 1 2 1 2 1 1 2 2 2 2 1 2 1 2 2 2 2 1 1 2 2 1 2 2 2 2 1 2 2 2 2 2 1 2 2 2 2 1 1 1 2 1 1 2 1 1 2 2 2 2 1 2 2 2 1 1 2 2 1 2 2 2 2 1 2 1 2 1 1 2 2 1 1 1 1 2 2 2 1 1 1 2 1 2 2 1 2 2 2 2 1 1 1 1 1 2 1 2 2 2 1 2 1 2 2 1 1 1 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C A T G C A A C C A A C G T T G G T A G C A A C C T A C G A T G C A A G C T A G G A A C G T A C G A T G C T A G C A A C C T T C G A A G G T T C C A A G G T A G G T T C G T T C C T A G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A T G G T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G T A C C A A C C A A C G T T G C A T G C T A G G T A G C T T C C A A G G T A C C T A G G T A C G T A G G A A G C T A G C T A C C T T G G A A G C A A G G A T C C A A C C T A C G T T G C T A C G T A G C A A C G T A G G T T G C T A C C T T C G T A G G T A C G A A G C T A G C A A G C A A C G A A G G A A G G T A G C T A C C T A G C A A G G T T G C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A C C T A G C T T G C T A G G A A G G T A C C T T G C A T G C A T C G T T G C T T C G A A C G A A G C T A C C A T G G A A G C T A G C A T C C A A G C A A C C T A C C T A G G T T C G A T G C A T C G A T C C T T G G A A G C A T G G T A G G T A C C A A C G T A C G A A C G T A G G T A C C A A G G T A C C A A C C A A C C A T C C T A C C T T G C A T C G A A G C T A C C T T G G A T C G A T G C T A G G T A G C A A G C A A G C T A G G A A C G A A G C T A C C T T G C T T G C A T C C T A C G T A G G T T G C A A G G A A C C T A G G A T C C T A C C A A G C A T C C A T C G A A C C T A G G A A C G T A G G T A C C T T C C A T G C A T C G T A G G A A C G A T G C A T C C T T C C T A G C T A C G T A G G T T G C T T G G T T G G T T C C A T G G T A G G T A G G T A C G T A C C A T G C T A G C T T G G A A C C A A G C A T C C T T G C A A C C T A C G T T G C A T G G T T G C T A C C A T C C T T C G A A C G A A G G T A G C T A C C T T G C A T G C A A C C A T G C A A G G T A G C A T G G T A G G A T G G A T G G A T C G T A C G A A C G T T C C T T C C T A G G T A C C T A C C T A G C T T C G T T G G A A G C T T C C T A G C T A C G T T C C T A G C T A G C T T G G T A G C T A G G A A G G A T C C T T C C A T C G A A C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T A G G A T G C T A C C T T G C T A G G A A G C T A C C T A G C T A C C A A C C T A G C T A G G T T G C A A G C T T G G T T G C T A G G A A C G T A G C T T C C A A G C A A C C T A G G T A G C T A C G T A C G T +A G C T A G G T A C G T T G C T A G C T A G C T A G G T A G C T A C C A A G G A T G C T T G C T A G G A A G G A A G C T A G G T A G C A T G C T T G C T T G C T T G G T T G C A T C G A T G G T A C G T T G C T A G C A T C G T A C C T A G G A T G G A T G C A A C G T T G C A A C C T T C G A T G C T T G G T T G C A T C C A A C C T T C C A T C C T T C C A T C G A A G C T A C C A T C G T T C G T A G C T T G C T A C G A A G G T T G C T A G C T A G G A T G C T A G C A A G C T A G C T A G G A A C C T A G C A A G G A A G G T A C C T A G C A A C G A T G G T A G C T A C C A A C G A T G C T A G G A T G G T T G G T T G C A A G C A T G C T A C G A A C G T A G G T A C G T T C G T A G G T A C C A A G C A A G G A A C G T A C G A T C C A A C C T T G C T T C G A A G G A T C C A T C G A T G G T T C G T T C C A T C G T A C G T T G C T A C G T A C C T A C G A A G G A A G C A A C C T T G C A A C C T A C C T A G C T A C G T A G C A A G C T T G G A A G C A A C C A A C G T T G C A T C G A A G G T A G C A T C C A A G G T A C G A T G G T A G G T A G G A A G C A A G C A A C C T T G G T A G C A A G G A T C C A A C C T A C C T T G C A T G G T T G G A A G G T A G G T T G G A A G C T T C G T A G G T A C C A A G G A T G G A T C C A A C C A A C G A A G C A A G G T T C C A A C C A T C G T T G C T A C G A A G G T A G C T T G G T T C C A A G C T T C C T T C G T A G G T T G C T T G C A A G C T A C C T T G C A T G C A T C G T T G G T T G C A A G C A T G G A A G C A T G C A T G C T T G C A T C C A A C C A A C C T T C C T T G C T T C G A A G C A T C G T T C C T T G G A A G C A T G G T A G G T A G C A A G G T T C G A T G G T A C C T T C G A A G G T A C C T T G C T T C C A T G C A A C C T T G C A T C G A A G C T T C C A T G G T A C G A A G C T T C C T A C G T A G C A A C C T A C G T T C C A A G C T A G G T T G C T A C G A T C C T T C G T A C G A A C G A A C G A A C C A A G G A T C C T A C C T T C G A A C C A T G G A A G G A T G G T A C G T A C G T T C C T A G C A T G C A T G G T A G G T A G C A A C G A T C G A T C G A T C C T T C G A A G C T T G C T T G C T T G G T T G C T T C C T T G C T A G G T A C G T A G G A T G C T A G C A A G G A A C C T T G C A T G G T T G C T A C C T T G C T T G C A A G G A T C G T A C C A T C C T T C G A T C G A A G C T A C C T A C C T T G C A A G C A A C C A T G C A T G G T T G C A T G G T A G G A A C C T A C G T T G G A A G G A A G G T T C C T T G C A A C G T T G C T A G C T A G C A T C C T T G G T A G C T A C C T A G G T T C G T T C G T A C C T T G C T A G G T A G C T A C G A A G G A T G C T T C C A T C G T T C C A A C C T A C G T A C G A T C C A T C C A T G C T T G G A T G C T A C C A T G C T A G C T A C G T T G C T T G C A A C C T T G C T T G G A A G C T T C C T A G C A A C C A A C C T T G C T A G G T T G C A A G C T T G G T T G C T A G C T A C C T A G C T A G G T A C C T T G C T A G C T A G C A A C G T A C C T CHA_2138 # subpop. label: 8 (internally 8) -2 1 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 1 1 2 2 1 2 2 1 1 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 1 2 2 2 2 1 2 1 1 2 1 1 1 1 2 1 1 1 1 1 1 2 1 2 1 1 2 1 1 2 2 2 2 2 2 1 2 1 2 1 2 1 1 1 2 1 1 2 2 2 1 1 1 2 2 2 1 1 1 2 1 1 2 2 1 2 1 1 1 1 2 2 1 2 2 2 1 2 2 1 1 1 2 1 1 1 2 2 1 2 1 1 2 2 1 1 1 1 2 1 1 1 1 1 1 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 1 1 2 2 1 1 1 2 2 1 1 2 1 1 1 1 1 1 1 2 2 1 1 1 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 2 1 2 2 2 2 1 1 1 2 1 2 2 1 2 1 2 2 2 1 1 2 1 2 2 2 1 2 2 2 2 2 1 2 2 1 1 2 1 1 1 2 1 2 1 2 1 1 2 1 2 2 2 2 1 1 2 2 2 1 2 1 2 2 1 1 2 1 2 1 1 1 2 1 1 2 2 1 1 1 1 1 2 1 1 2 1 2 2 2 2 2 2 1 2 1 2 2 2 1 2 2 1 2 2 2 2 1 2 1 1 1 1 1 2 1 2 1 2 2 2 1 2 1 2 2 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 2 1 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 2 2 2 1 2 2 1 1 2 2 2 1 1 1 1 1 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A G G A A G C T A G C A A C C T A C G A A G C A A C C A A G C T A G C T T G C A T C G T T C C T A C C T A G G A A C C T A C G T T G C T T C G A T G C T A G G A A G G T A C G T A C G A T C C T T G C T T C G T A G C T T C C T T C C A T G G T T G G T T G C A A C C A T G C A T G G T T C C A A C C A A G C A A G C T T G C A T G G T T C G T A G C A A G C T T C G A T C C A T C G A T G G A A G C T T C C T T G C T A G G A T C C T A C C T T C C T A G G T A G C A T G G T T G C T T G C T A G G T A G C A T C G A A G C A T G G T T G G A T C C A T C G A T C C T A G G T A G C A A G C T A C C T T C C T A G C T A C G A A G C T T G C A A C C T A G G A T G G T T C G T A C G A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T T G G T A C C A A G C T T C C T A G G A T C G A T C G T A G G A A G C A T G G A T C G A T C G A T C C T A G G A A C C T T G C T A C G A A C G T A C C A T C C T T G C T A G G A A C G T A C G T A G C T T C C T T C C T T C C A T G C T T C G T A C C A A C C T T G G T T G C T T C G T T G G T T C G A A C C T T G C A A G C A A G C T T C C A A G C A A C C T T G C A A C G A T G C A A G G T T G G A A G G T A G G A A G C T T G C T T C G A T C G T A C G A T C C T T C C T A G C T T G C T T G C T A C G T T G G A T G C A T G C T T C C T T G C T T C G T T G C T A G C A T G C A T G C T A G C T A G C A A G C A A G C T T C C T T C G T T G C T A C G A A C G T A C C A A C C A A C G A A G G T A G C A T G C T A G G T T G G T T C C T A C G T A G C A A G C A A C C A T C C T T G G A A G C A T C C A T G C T A C G A A C C T T G C A A C G T T G C T A G G T T C G T T C C T A G C A A C C T A G C A A C C A A G C A A C C A A G C T A C C A A G G T A C C T +A G G T T G G A T C C T A G C T A C C T T C G A A G G T T G C A T C C A A C G A T C C T T G C A T G G A A C G A T G C T A G G T T G C T A C C T T G C T T G C A T G G T A G C T T C C A T G G A A C G A T C C T A C C T T G G T A G C T A G G T A G C T T G C T A C G T T C C T T C C T T C G T A G G T T G C T A C G A T C C T A G C A A G C A T G C A T C G A T G G A T G C T T C G A A G C T T C G T T G G T A G G A A G C A A G G T T G C T A C C T A G C A A C G A T G C A A G C A A C G T A G G T T G G T A C C A A G G T A G G T T C C T T C C A T G G A A C G A A G G T T G C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A A G C A A C C A A G G T A C G T A G G T A C C T A G G T T C G A T C G A T C C T A G C T T C G T A C G A A G C A A C G T T G G A T C G T T C C T T G C A T G C A A C C T T C G T A G G A T C G A A G G A A G G A A G G T T G G A A C C A T C G T T G G A A C G A A G C A A G C A T C G T A C C A T G C T A C G T T G G A T C C A A G G A T C C T T G G T A G G T A C G T T G C A A C G T T G G T A G G T T C C A T C G A T C G T T G G A T C G T T C C A T G G T A C G T T G C T A C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A T G G A A C C A A G C T A G C A A G G T T C G T A G G A T C G T T C C T A C C T A G G A A G C T T G G T A G C T T G G A T C C T A G C T A G C A A C G T A G C T T C C A T G C T T C G T T C C A T C C T T C C A A G G T A G G A A G C T T C C T A C G A A G C T A G C A T C G A A G C A A G C T T G C T T G C T T C G A T C G A A C G A T C G A T C G A T C C A T G G A A G C T T C C T T G C T A G G A T C C T A C C T T G G T T G C T A C C T A C C A A C C T T G C T A C C T A G C A T C G A A G C A T G G T T G G A T C C A T C G A T C C T A G G T A G C A A G C T A C C T T C C T A G C T A C G A A G C T T C G A T G C T T G C A T G G A A G C T T C G T A G C A A G G A T G C T T C C T T G C T T C C A T G G A A C G A T G G T A C C T A G C T A C C T A G C A T G G A T G G T T G C A T C G T T G G A T C C A T C G A A G C A T G G A A G C T T G C T T G G A A C G T A C C A T C C A A G G A A G C T A C C A A C G T A G C T T C C A A C G T T C C T T G G A A G C A T G C A A C C T T G C T T G C T T G G A T G G T A C C A T C C T A C C T A G C A A G G A A C G T A G C T T C G A T G C A A C C A A G C A A G G T T G G A T C G A A G G A A G C T A G G A T C G A A G G T A C G A T C C T A G C A A G G T A G G T A G C T A C C T T G G A T G C A A G C T A G G A A G C A A G C T T C C T A G G T T G C A T G C A A G C A T G C A A G G T A C G A T C C T T G C T T G C T A G C A T C C T A C G A T C G A A C C A A G C A T G C A T G C A A C G T T G G T T C C T A C G T A G G T A C C A A C C A T G C T T G G T A G G A A C G A T G C A A C C A A G C T T G C T T G G T T C G A A C C T T C C T T C C A A G C A A C G T A G G T A C C A A G C A T C C T A G G T A G G A A G G T A C C T CHA_2139 # subpop. label: 8 (internally 8) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 1 2 1 2 2 2 2 2 1 2 1 2 2 2 1 1 2 1 2 1 1 1 1 2 2 2 1 2 2 1 2 1 1 1 2 2 1 1 1 1 1 1 2 2 1 2 2 2 2 2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 1 2 1 1 1 1 1 1 2 2 1 1 1 1 2 2 2 2 1 1 1 2 1 2 1 2 2 2 1 1 2 2 2 2 1 1 2 2 2 2 1 2 1 1 2 2 2 1 2 2 2 1 1 1 2 2 1 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 1 1 2 1 1 1 2 1 1 2 1 2 1 1 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 1 2 2 2 1 1 2 1 1 2 2 1 1 2 1 2 1 2 2 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G T A C G T A C G A A G G T T G G T T C G A A G C T T G C A T G G T A G C T T C C T A G C A A C C A A G C A A G G A A G G T A G G A A C C T A C C A A G G A A C G A A G C T T C C A T G G T A C C A T G C T A C C T T G G A T C C T A G G A T C C T T G G A A G G T A C G A A C G T T C G T A G G A A C G T A G G A T C G A T C C T T G G A A G C T A C G A T G C A A G G T T C G T T C G T T G C A A C G T T G G A T C C A A G G T T C C T T G G T A C C A A G C T T G C A A C G A A C C A A G C A A C C A A G G T T C G T A G C A T G G A T C C T A C G T A G G A A G C T A C G A T G G A T C C A T G C T T G G A T G G T A C G T A G C T T G G T T G C A T G C T A C G T T C C T T C C A A G G T A G G T T G C A A C C A T G C A T G G T T C C A A C C A A G C A A G C T T G C A T G G T T C G T A G C A A G C T T C C A T C C A T C C A T G G A A G C T T C C T T G G T T G C A A C C A A C C T T G G T T G C T A C C A T G C T T C C T T C C T A G G T A G C A T C G A A G C A T G G T T G G A T C C A T C G A T C C T A G G T A G C A A G C T A C C T T C C T A G C T A C G A A G C T T G C A A C C T A G C A T G G T T C C T A C G A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A G G T A G G T A C C A A G C T T C G T A C G A T C G A T C G T A G G A A G C A T G G A T C C T T C G A T C C T A C G A A C C T A G C T A C G A A C G T A C C A T C C A T G C A A G G T A C G A T C C T T G C A T G C T T C C T T C C A T G C A T G G T A C C A A G C T T G C T T G G T A G G T A G C T T C G A T C C A T G G A A G C A A G G A A C C A A G C A A C C T T C C A T C G T T G C A T G G A T C G A T G C T T G C A T G C T A G C T T C G A A G G A A G G T T C C T A G C A A G G T A C G A A G C A T C C T A G G A T G C A A G C A A C G A A G G T A G C T T C C T A G C T T G C A T G C T A G C T T G C A A G G A T C C T A C C T T C G T T C C T A G C T A C C T A C G A T C G A A C C A A G C T A G G A T G C T A C G T T G G T T C C T A C G A T C G T A G G T A G C A T G C A A G C A A G G A A C G T A C C T A G C A T C G T T G C T A C C T T C C A A G C T T G C T T C C T A G G A A C G T A G G T A C C A A G C A T C C T A G G T A G G A A G G T A C C T +A G C A A C G T A C C T A G G A T G G A A C G A T G G T T C G T T C C A A G G A T G C T T G C T A C G A T C C T T C G T T G G T A C C T A C G T T G G A A C C T T G C T A G C A T C G A T G G A A C G A T C C T A C C A T G G T A C G A A G C A A G C A T G G T A G G A T G C A A G C T T C G T A G C T T G C T A G C T T G C A A G C T T C C A T G C A T C C T A G G T A G C T T G C A T G G T T C G T A G G T A G G A A G C A A G G T A G C T A C C T A C G A A G C T A G C A A G C A A C G T A G G T T C G T A C C T A C C A T G G A A C G T T G C T T G G A A C G A A G C A A C C A A C G A A G G T A G G A T G C A A C C T T G C A A C G A T G C T A C C A A G G A T C C T T G G T A C G A A G C T T G C T T C C A T G G T A C C A T G G A T G C A T C C T A G C A A G G T T C G T T C G A A C G T T G G T T G G A A G C T T G C A T G G T A G C T T C C T A G C A T C C A A G C A A G G T A G G A T C G T A G C T A G C A A G C T A C C A A G C T A G C A T G C T T C C A T G G T A C C T T C C A T G C T A G G T A G C T T G G A A G C T A G C T T G G T T G C T A G C T A C G T T C C A T C G A T C G T T G G A A G C T A C C A T C C A A G C T T G C A T G G T T G C T A G G T A C C T T G C T T G G T T C C T T G G T A C C A A G C A T G C A A G C T T C C A A G C T A G G T T G G T A G C T T G C A T C G T T G C T A C G T A G G T T C C T T C G A T G G T T G G A T C C T T G G A A G G T T C C T T G C A T G C A T G C A T C G T A G C A T C C T T G G A T G C A A G C A T G G A A C C A T C G A T C G A T G C A T C C A A C C A A G C T T C C T T G G T T C C A T G C A T C G T A C G A T C G A T C C A T G G A T C C A A C C A A G C T A C G A T C C T A C C T T G G T T G C T A C C T A C C A A C C T T G C T A C G T A C C T T C C A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T C G A A G C T A G C T A G C T T G C T T G C A A C C T A G G T A C G A A C G T A C G A A C C A A G G A T G C T A C C A T G C T T C C A T C C T A C G A T G G T A C C A A G C T T C C T A G C A T G G A T G G T A G C A T C G T T G G A A G G A T G C A T C C T A G G A A C C T T G C T T G G T T G G A T G C A T G G T A G G A A G C T A C C A A C G T A G C T T G C T A C C T A C C T A G C A T C C T A C C A A C C T A C G T T G C A A G G T T G C T A C G A T C C T T C G A A G G A T G G A A C G T A G C A A C C T T C C A T C G A T G C A A G G T T G C A T C G A A G G A T G C T T G G T A C C T A G C A A C G T T C C T T G C A T G C A T G C A A G C A T C C T A C G T T G C A T G C A A G G T T G G T A G C T T C C T T C C T A C C A A G G T A G C A T G C A A G C T T G G A A C C A T C G A T G C A A G G T A C G T A C G A T C C A T C G A A G G T A G C A T G C T A G G T T C G T T C C T A C C T T C C A A G C A A G C T T G C T T C C A T C C T T C C T T C C A A G G T A G G T T G C A A C G A A C C T A G C T T C C T T C C A A G G A A C G T A G C T T G C A A G C A T C G T T G C A A G C A A C C T A G C A CHA_2140 # subpop. label: 8 (internally 8) -1 1 2 2 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T G G T T G C A T G C A A G C A T G C A A G G T A C C T T C C T T C G T T G C T A C C A T C C A A C G A T G G A T C G A A G C A T C G T T C G A A C C A T G G A T G C T A C C T A G G A A C C T A C G T A G C T T C G A T C C T T C C T T C C A A G G T A G G T T G C A A C G A A C G A A G C T T G C T T C C T A G C A A C G T A G G T A G C A A G C A A C C T A G C T A G C A A G C T A C G T CHA_2141 # subpop. label: 8 (internally 8) -2 2 1 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 1 2 2 2 2 2 2 2 1 2 1 2 1 1 1 2 2 1 1 1 1 1 1 2 2 2 1 2 2 2 2 2 1 2 1 2 1 1 2 2 2 2 1 2 1 2 2 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 2 1 1 2 1 2 1 2 1 1 2 1 1 2 1 2 2 1 2 2 2 1 1 1 1 2 2 2 2 2 2 1 1 2 2 2 2 1 1 1 2 2 2 1 2 2 1 1 2 2 1 2 2 2 1 1 1 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 1 2 1 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 2 1 1 2 2 1 2 1 2 1 2 2 2 2 1 1 1 2 2 1 1 1 2 2 1 1 2 2 1 1 1 1 1 1 2 2 1 1 1 1 2 2 2 1 2 1 2 1 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 2 1 2 2 2 2 1 1 1 2 2 2 2 1 2 1 2 2 2 1 1 2 1 2 2 2 1 2 2 2 2 2 1 2 2 1 1 2 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2 2 1 2 1 2 1 1 2 2 2 2 2 2 1 2 2 2 1 1 2 2 2 2 1 1 2 1 1 2 2 2 1 2 2 1 2 1 2 2 2 1 1 1 2 2 2 2 2 1 1 2 2 1 2 2 2 1 2 1 1 2 +A G G T A C G T A C G T T G C T A C G T A G C T A G G T T G G A T G C A T C G A T G C T T G C T A G G T T G G A A G C T T G G T A G C T A C C T T C C T A C C T T G G T A G C A T G G T T G G A A C G T T G C A A G C A T C G T A G C T A C G T A G C A T C C T A C C T T C C T T G C T T C G T A G G T T G C T T C C A T C C T T G G A A G G A T C C A T C C T T G C A T G C A A C C A A G C T T C G T A C G A A G G A A G G A T C G A A G G A T C C T A C C A A C G A T G C T A G C T A G C T A G G T T C C T A C C T A G G A T G C T A C C A A G C A T G G T A G G T A G C T T G C A T G G A T G G T T G G A A C C T A G G A A G C A A C C T T C C A A C G A A C G T A C G A T C C A T G G T A G C T A C C A A G C A A G G T A G C A A C G A T C C A T C C T T G G T T C G A A G G T A G G T T C G T T C G T A C G A A G C T T G C A T G C A A G C A T C G T A G C A A G G A A G G A T G G A A G G T A G G A A C C T A C C T A G G A A G G A T C C T A C C A T G G T A G C A T G C A A C G T T G G A T C C T A G C A T C C T T G G A A G G T A G C T T G G T A C C T A G C A A G G T T C C A T C G A T C G T A G C A T C G T A C C T A C G T A C G A T G G A A C C T T G C A A C G T T G G A T C C T T C C T T C G T A G G T A G G A A C G T A G C A A G G A T C C A A C G A A C C A A G G T T C G A T G C A T C G T T C C T A C C A A C G T A G G A A C G T A G C A T C G A T C C A T C C T A G G A T G C T T C C T T G C A A C C T T G G T T G C T T C C T T G G T T G G T T G G T T G G A T C C A T C G A A G C T A G G A T G C T T C C T T G C T T G C T T G C T T C C A T G C A A C C T A C G T T C C A T C C A T G G A A G C T T C C T T G C T A G C A T C C A A C C T T C G A A G G T A G C A A C C A A G C T T G C T A C G T A C C T T C C A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T G G A A C C A T G G T A C C A A G C T T C G A T G C T T G G A T G G T T C G T A C G A A C C T T C C A A C G T T C G T T G C A T C C A T G G T A G G A A G G T A C G T A G G T A C C T A C G A T G G T T C G T A G G A T C G A T G G A A G G A T G G T A C C T A G C T T G C T T G C T T G C A A C G T T G C T A C C A T G C A A G G T A C G A A C C T A C C A A G C A T C C T T C C A T G C T T C G T A C C A A C C A A C C T T G C T A C G T T G C T T C C A T C C T T C G A A G G A T G G A A C G T A G C A A C C T T C C A T C G A T G C A A G G T T G G T T G G A A C C A T G C T T G G A T C G A T G G A A G G T T C C T T G C A A C G T T C G A A G C T A G G T T C G T T G C A T G C A T C C A A C C A A G C T T C C T A C C A A C C A A C G T A G C T A G G A T C C A A C C T A C G T T G G T T C C T A G C A A C C T A C C A T G C A A G G A T C C T A G G A T G C T A C G T T G G T T C C T A C G A T C C A A G G A A G C T T G C T T C C A T C C T T C C T T C C A A G G A A G G T A G C A A C C T T C C T T G C A T G G T T C G T T G C T A C G T A G C A T G C A A G C A A C C T T G C T A C C T A G G T A C C T +A G G T T C G T A C C T A G C A T G G A A G G A T G C T A C G T A G C A A G G T A G G A T C G T T G C T T G G A T G C A A C C A T G C A T G G T T G G A A C C T T G C T A G C A T G C T T G G A T C C T T G C T A G C A A G G T T C G T A G C T A G G A T G C A A C G T A G C T T C C T T G C T A G C T T G C T A C C A T C C T A G C T T C C A A C C T T C G A A G G A T G C T A C C A A G C T T C G T A C G A A G G A A G G A T C G A A G G A T C C T A C C A A C G A T G C T A G C T A G C T A G G T T C C T A C C T A G G T A G G T T C G T A G C T T G G A A C G A A G C T A C C A A C G A A G G T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A A G C T A C G T A G G T A G G A A C G A T G G A A C C A T G G A T G C A T C G T T G G A A G G A A G G A A G C A A C G T T C G T A C G A A G C T T G C A T G G T A G C T T C C T A G C A A C G A A G G A T G G T T G C A T C G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T G C A T G C A A C G T T C C A T G C T A G G T T C C T T G G A A G G T A C G T T G C A A G C T A G G A A G G A T G G A A G G A A G G T T G G A T C G T A C G A T C C T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A G G A A G G A T G G A A G C A A C C A A G C T A G G T T C G A A G C A A G C A T G G A T C C T A C G A A G G T A G C A T C G A A G G T T C G A T C C T A G C T A G G T A C G T A G C T T C C A T G C A T C G T A C C A T C C T T C C T T G G T T G G T T G C A A C C A T G G A T C G A T G C A T G C A A C C A A C C T A G C A A C C T T C C A T G G T A C G A T C G T A C C T A G C T T G C T A G G T A G C T T G G T A C G A T G C A A C C T A G G T A G G T A C C A A C C A A C G A T C C A A C G A T C G A T C G T A G C A T G G T T C C A T C G A A G C A T C C T T G G T A G C A A G C T A C G T T C C T A G C T A C G A A G C T T G C A A C C T A G G A A G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G A A G G T A G G T A C C A A G G T A C G T A G G A T C G T A C G T A G G T A G C A T G G A A G G A T G G T A G C T A G G A A G C T T G C T A C G A T G G A T G C A T G G T T G G A A G G T A C C A A C G T T G C A T G C T T C C T T C C A T G C A T G G T A C C A A C C T T G C T A G G T A G G A A G C T T C G A T C C A T G G A A G C A A G C T T C G A A G C T T C C T T G C A T C G T T G C A T G G A T C G A T G G T A G G A T G C A T G G A T G G A T C G T A C G A T C G T T G C A A G G T A C G A A G C A T C C T T G C T A G C A A G C T A C G T T G G T T C G A A C C T A G G T T G C A T G C T A G C T A G C A A G C A A C C T T G C A T G G T T G C T T C G A A C G T A C C A A C C A A C G A A G G T A G C A T G C T A G G T T G G T T C C T A C G T A G C A A G C A A C C A T G C T T G G T A G G A A C G A T G C A A C C A A G C T T G C T T G G T T C C T A G C T T G C T T C C T A G G A A C G T A G G T A C C A A G C A T C C T A G C A T G C A A G C A A C G T CHA_2142 # subpop. label: 8 (internally 8) -2 2 2 1 2 1 1 2 2 1 2 2 2 2 1 1 1 2 1 1 1 2 2 2 1 2 1 2 1 2 1 2 1 1 2 1 2 1 1 1 1 2 2 2 1 2 2 1 1 2 2 2 1 2 1 1 1 1 2 1 2 1 2 1 1 2 2 2 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A C C A T C G A T G G A T G C A T C G A A G C A A G C A A G C A T G C T T C G T T G C T A C G A T C G A T C G A T G G A T G G A A G C T T C C A A G C T A C G A T C C A A G G T T C C A A G G T A C C T A C C A A G C T T G C T A C G A T G C T T C G T A G C T T C C T T G G T A C G A T G G T T G C T A G C A A C C A A G C T A G G A A C G A A G C T A G G A A C C T T G C T A C C T A C G A T G G T T C G T A C G A A C C T A G G A T G C T T C C A T G C T T C C A T C G T A C G T T G G T A C C A A G C T T C C T A G G A T C G A T C G T A G G A A G C A T G G A T C G A T C G A T C C T A G G A A C C T T G C T A G C A A C G T T G C A T C C T T G C T A G G A A C G T A C G T A G C T A G G A A C G T T C C T T G G A A G C A T G C A A C C T T G C T T G C A T G G T T G G T A G C A T C G T A C C A A G C A A C C T A G C T A C C T T C C T T G C A T C G T T G C A T G G T T C G A T G G A A C C A T G C A T G G A T G G A A G G A A C G A T C C T T C C T A C G T T G C T A G C T A C G T T C G T T C C A A G C A T C C T A G G T T C G A A C C T T G C T A C C T A G C T A G C T A G C A A G C A A G C T T C C A T C G A T G C T A G C A A C C T A G C A T C G A A C C A A G C T A G G A T G C A T G C A A G C T T C C T A C C T T C C A A G G T A G C A A G C T T G G T A G G A T C C T T G C T A C G A A G C T T G G T T C G A A G C T A G G T A G G T T C C T A G G A A C G T A G C T T G C T A G C T A C C T T G C T A G C A A C C A A C G T +A G C A A C G T A C G A A G G T A C C T T G C T T G C T A G G A T C C A A G G A T C C T T C G T A C G A A G G A A G G T T G G T A C C A T G G T T G G A A C C T T G C T A G C A T C G A T G G A A C G A T C C T A C C A T C C A T C G A A G C A A G C A T G G T A G G A T G C A A G C T T C C T A G C T T G C T T C C A T C C T A G C A A G G A T G C A T C C T T G G T T G C T A C C A A G C T T C G T T G G T A G G A A G C A A G G T A G C T A C C T A G C A A G C T A G C A A G C A A C G T A G G A T C G T A G C T T C C A T G G A A C C T T G C T A G C A A C G T A G G T T G C A A C G A A G G T A G G A T G C A A C C T T G C A A C G A T G C T A C C A A G G A T C C T T G G T A C G A A G C T T G C T T C C A T G G T T C G A T C C A T C G T T C G T T G G T T G G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G G A T C C A A G C A A C C T T C G T A G G A A C C T A C C T A G C T A C G A A G C T T C C A T G G T A C C A T G G T A C G T T C C A T G C A T G G A T G C A T C G A A C G T A G C T T C C A A C C T T C G A A C G T A G C A A G G T A G G A A G G T A G C T A C G A T C C T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A G G A A G G A T G G A A G C A A C G A A G C T A G C A A C G A T G C T T G C A T C G T T G C T A C C T A G G A A G C T A C G T A C C T T G G A T C G T T G G T T G G T T C C T T G G A A G G T T G C A T C G T A G G A T C C T T G G A T G C T A G G A T G C T A C C A T C G A A G C T A G C A T C C A A G C A A G C T A G C T A G C T T C G A T C G A A C C T A C G A T C G A T G G T T G G A T G C T T C G T T G C T A G C A A G G T A C C T T C C T A G G T A G C A T C C T T C C A T C C T A G C T A C G A T C G T A G C A T G C A T G C A A C G T A G G T T C C T A C G T A G C A T G C T A C G A A G G A A C G A A C G A A G C T T G C A T G C T T C G A T C G T T C G T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T G G A A G G T A G G T A C C A A G C T T C G T A C C A T G C T T G G A A G G T A G C A T C G A T C G T T C G T T C C T A G C T A G G A T G C T A C G A A C G T A C C A T G G T A C C T A G G T A C G T A C C T T G C T T C C T A C C T T C C A T G C A T C G T A C C A A G C T T G C T A G C T T G G T T C C T T C G A A C C T T G C A A G C A T G C T T C C A A G C A A C C T T G C A A C G A T G C A A G G T T G G A A G G T A G G A A G C T T G G T A C C T A G C A A C G A T C C T T G C A A G G T A C G A A G C A T C C T T G C A A G C T T C G T A G G A A C C A A C G T T C C T A G G T T G C A T G C T A G C T T G C A A G G A A C G A T C C A T C G T T G C T T C C T A C C T A C G A T C C A T C G A A G G T A G C A T G C T A G G T T C G T T C C T A C C T T C C A A G C T A G C A T C G T T G G A A G C A T C C T A G C T T C C A A G C A T G C A A C C T T C C T A G C T T G C T T C C A A G G A A C C T A G G T A G C T A G C A A C C T T G C T A C C T A G G T A C C T CHA_3106 # subpop. label: 8 (internally 8) -2 2 2 1 2 1 1 2 2 1 2 2 2 2 1 1 1 2 1 1 1 2 2 2 1 2 1 2 2 1 1 2 2 1 2 2 1 1 1 1 1 2 2 2 1 2 2 1 2 1 1 2 1 1 1 2 1 1 2 2 2 1 2 2 1 1 2 1 1 2 1 2 1 2 2 2 1 2 2 1 1 2 1 1 2 1 1 1 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 2 2 2 1 1 2 1 2 1 1 1 2 2 1 1 1 1 2 1 1 1 1 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 1 1 1 2 1 2 2 2 1 1 1 2 1 2 1 1 2 1 1 1 1 1 2 2 2 2 2 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 1 1 2 2 2 1 2 2 2 1 2 2 2 2 1 2 2 2 2 1 2 1 2 2 1 1 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 2 1 2 1 1 2 2 2 2 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 1 1 2 1 1 2 1 1 1 2 2 1 2 1 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 2 1 1 1 2 1 1 1 2 1 1 1 2 2 2 1 2 1 2 2 2 2 1 2 2 2 1 2 2 1 1 1 1 2 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C A A C G T A C C T A G G A T G G A T G C T T G G T A C G T A C C T T C G A T G C T T G C A A C G T T C G T T C C T A C C T T C C A T G G T T G C T T G C A T G G A A C G A T G C T T G G T T G C T T G G T A G C A T G G T T C G T A C G A T G G A T C C T A C C T T C C A A C C T T C C T A G C T T C C A T C C A T C C A A G C A T C C A A C G T T C G A T G C T A G C T A C C T T C G T A C C A A G G A A G C A A G C A A G C T T G C T A C C A A G G A A C G A T G C A A G C A A C G T A G G T T C C T A G G A A G G T A G G T T C C T T C C A T G G A A C G A A G G T T G C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A A G C A A C C T A G G T A G G T A C G A T G G A A C C A T G G A T G C T T C G T A G C T T C G T T C G A T G G A A C C T T G G T T C G T T G C T T G C A T G G T T C G T T C G T T C G A A G G A A G C A A G G A A G G T T C G A A C C T A G C T A G G T T G G A A G C A A G G A T C G T A C C A T G C A T C G A A G G A T G C A T G C A T C C A A C G A A C G T A G G A T G C A A G C T A G G T A C G T A C C A T G G A T C G T T G G A A G C T A C G A T G C T A C C A T G G A T C G T A G C T A C C A A C C T A G C A A G C A T C C T T C C T T G G A A G G A T G G A A G C A A C C A A G C T A G G T T C G A T G C T T G C A A G G T T G C T A C C T A G G T T G C T T C G A A C C A T C G A T G C T A G G A A G G T T C C T T G C A A G C A T G C A T C G T A G G T T C C T T C C A T G C A A G C A T G G A A C C A T C G A T C G A T G C A T G C A A C C A A C C A A G C A T G C T T C G T T G C A T C G T T C C A T C C A T C C A T G G A A G C T T C C A A G C T A C G A T C C A A G G T T C C A A G G T A G C A T G C T T G C T T C C A A C G T A C C T T C C A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T G G A A C C A A G C T A C G A A G C T T G C A A C C T T C G A A C G A T G C T A G G A T C C T A G G A T G C T T C C A A G C A T C C T A G G T A C G A T G G T A C G A A G G T A C G T A C G A T G C A A C G T A G G T A G C A T G G A A G G A T G G T A C C T A G C T T G C T T G C T T G C A A C G T T G C T A C C T A G C T A G G A A C G T A C C T A C C A T G C T T C C T T C C A T G C A T G G T A C C A A C C T A C C T T G G T A G G T A G C T A C G A A C C A T G C T A G C A A G C T A G C A A G C T A C C T T G G T A C C A A C G T T C C T T G C A T G G T A G C T T G C T T G C T T C G A T C G T A C C A T C C T T C C T A C G T T C C T A G C T T G G T T G C T A G C T A G C T A G G T A C C A A G C T T C C T T G G T T G C A T G C A A G C A T G C A A G G T A C G A T C C T T G C T T G C T A G C T A C C T A C C A T G C A T C G A A G C T A G G T A C C A T C G A T G G T T C G A A C C T T G G T T G C T A C C A A G C T T G G T A G C A A C G A T C C A A G G A A G C T T G C T A C G T T C C T A G G T A G G T T C C T A G G A A C G A A G G T A G C T A G C A A C C T A G C T A G C A A G C T A C G T +A G C T A C G T A G C T T C C A T G G A A G C T A G G T T G C A T C C A A G G T A G G A T G C T A C G T T C G A T C C T A C C A T G C A T C G A T G G A A C C T T G G A T C C A T G C T T G G A A C G A T C C T A C C T T C C T A G C T A G G A T G G A T G C A A C G T T C C A A C C T A C C T A G C T T G C T T C C A T C C T A G C A A G G A T G C A T C C T T G G T T G C T A C C A A G C T T C G T T G G T A G C A A G G A A G G T T G C T A C C T A G C A A G C A T G C A A G C A A C G T A C G A T C C T A G C T T G G T T G G T A C C T T G C T A G C A A C C A A G G T T G C A A C G A A C G T T G G A T G C A A C C T T G G T A C C T T G G T T C C T A G G A A C G A A C C A T C G A A G G T A C C A A G C A A G C T A G G T A C G T T G C A T C G T A G C A A G G T A C G T A G G T T C G T T C G T A C G T T C C T T G C A T G G T T G C T T C G T A G G A T G G A A G C A A G G A A G G T T C G A A C C T A G C T A G G A A C C A A C G T A G G A T C G T T C C A A C C A A C G T T G G A T G C A A G C T A G C A A G G A A G G T A C G T T G C T T G C T A G G A A C G T A G C A T G C A A G G A T G G T A G C T T C G A T G G T A C G T T G C A T C G A A C C T A C G T T G G A T C C T T G G A T C C T T G C A T G G A A G G A T G C A A C C A T C G A A G C T A G C A A C G A T G C T A G C A T C G T T C C T A C G T A G G A A C C T T C G A T G G T T G G A T C C T T G G A A C C T A C C T T C G T T G C A A G C T A G G T A G C A T C C T T G G A T G C A A G G A T G C A T C C A T C G A T C G A T G C A T C C A A C C A A G C T T C C T T G G T T C C A T G C T A C G A A C G A T C G A T G G A T G G A T C C A A C C A A G G T T G C A A C C A A C C T T G G T T G C T A C C A T C C T T C C T T C C T A G G T A G C T A G C A A G C T A C G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T G G A A C C A A G C T A C G A A G C T T G C A A C C T A G G A T G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G A A G G A A G G T A C G T A G G T A C C T A C G A T G G T T G G T A G G T A G C A A C G A T C G A T C G A T C C T T G G A A C G A T G C T A C C A A C G T T G C T A C C A T G C A A G G T A C C A A C G T A G C T T C C T A C G T T C C T T G G A A G C A T G C A A C C T T G C T T G C T T G G T T G G T T C G A T C C A T G G A A G C A A G G A A C G T A G C A A C C T T C C A A C C A T C C A A G G T T G C A T G G T A G G A A G C T T G G T A C C T A G C A A C G T T C C T T C C T A G G T A C C T T G G T T G C T T G C A A G C T A G C T A C G A A G G T T C G T T G G A T C G A A G C T A C G T A G C T A G C A A G C A A C G A T C C T T G C T T G C T A G C T A C C A A G C A T C G A A G G A A G C T A G G A T G C A T C G A T G G T T C C T A C G T T C C T T G G T T C C A T G C T T G G A A G C A T C C T T G C T A C C A A G C T T G C T T G G T T C G A A G G T T G C T T C C T A G C A A C G A A G C A A C C A A G C A A C C T A G G T A G G A A G G T A C C T CHA_3111 # subpop. label: 8 (internally 8) -2 1 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 1 1 2 2 1 1 2 2 2 1 2 2 2 2 2 1 1 2 1 2 1 1 1 1 2 2 2 2 2 2 1 2 1 1 1 1 1 1 1 1 1 1 2 2 1 2 1 1 2 1 1 2 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 2 2 2 1 2 2 1 2 2 2 1 1 1 1 2 2 1 1 2 2 2 1 1 2 1 2 1 1 2 1 1 2 1 2 1 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A G C A A G C A A C G T T G C A A C C T A C C T T C C T A G G T A G C A T G G T T G C T T G C T A C G A T G C T T C C A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T C G A A G G A A G C T A G C T T G C T A C G A T G C T T G G T A G G A A G C T A C G A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A C G T A G G A A C C A A G C T A C G T A C G A T G C T T G G T A G G T A G C A A C G A T C G A T C G A T C C T A G G A A G C T T G C T T G C A A C G T T G C T A C C T T G C T A G G A A C G A A C G T A G C T A C C T A G C T A C C T T G C A T G G T A C C A A C C T A C C T T G C T T G G T T G C T T C G A A C C T T G C A A G C A A G C T T C C A A G C A A C C T T G C A A C G A T G C A A G G T T G G A A G G T A G G A A G C T T G G T A C C T A G C A A C G T T C C T A G C A A C G T T G C T A G C T A G C T T G G A T G C A A G C A T C C A T G G T T C G T T C C A A C C A A G C T T C G A A G C T A G C A A G G A A C G A T C C A T C G A T G C T A G C A A C C T A G G A 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T C C T T C G T A G C T T C G A A G G T A G G T T C G T T C G T A C G A A G C T T G C A T G C A A G C A T C G T A G C A A G G A A G G A T G G T T G C A T C G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T G C A T G C A A C G T T C C A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C T A G G A T G G A T G G A T C C T A G C T A G G T A C G A A C G T A C G T T C G T T C G T T G C A A C G T A G G T T G G T A G C A T C C T T G G T A C C A A G C T A G G A T C G A A C C A A G C T A G G T T C G A T G C T T G C A A G G T A G G A A C G T A G G A A G C T T C G A T G G T T C G A T C C T T G C T A G G A T G C T T C C T T C C T A G C A T C C T A C C A T C C T T C C T T G G T A G G A A G C A A C C A T G C A T G G T T C C A A C C A A G C A A G C T T G C A T G G T T C G T A G C A A G C T T C G A T C G A T C C A T G G A A G C T T C C T T G C T A G G A T C C T A C C A A G C T T G G A A C G T T G G T T G C T T G C T A C C T A G C A T C G A A G C A T G G T T G G A T C C A T C G A T C C T A G G T A G C A A G C T A C C T T C C T A G C T A C G A A G C T T C G A A C C T A G G A T G G T T C G T A C G A A C C T A G G A T G C T T C C T T C C T T C C A T G G A A C G A T G G T A C C T A G C T A C C T A C G A A C G A T G G T A G G T A G C A A C G A T C G A T G G A T C C T A C G A A G C T T G C T T G C A T G G T A C C A T G G T A G C T A G G T A C G T T C G T A C G T T C C A A C G T T C C T T G G A A G C A T G C A A C C T T G C T T G C A T G G T T G G T A C C A T C C T T C G A A G G A T G G A A C C A A G C A A C C T T C C A T C G A T G C A A G G T T G C A T C G A A G G A A G C T T G C T T C G A T C G T A C C A T C C T A G C A A G G T T G G A A G C T A G C T T G G T T G C A T G C T T C C T T G C T A G G T T G G A T C C T A C G T A G C A A G C A T G C A T C C A A C C T A C G T T C G T T G C A A G C A A C C T A G G A T G C A T C G A A G C T A G G T A C C A A C G T T G G T T C G A A C C T T C C A A G C T A G C A T C G T T G C A A G C A A C G T A C C T T C G T A G G T A G C T A C C T T C C T A G C T T G C T T C C A A G C A A C G A T G C T T C C A A G C A A C C A A G C T A C C A A G G T A C C T CHA_3113 # subpop. label: 8 (internally 8) -1 1 2 1 2 1 2 2 2 1 1 1 1 2 2 2 2 1 1 2 2 1 1 2 2 2 2 2 2 1 1 2 1 1 2 1 2 1 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 1 1 2 2 2 1 1 1 2 2 2 2 1 2 2 1 2 2 1 2 1 2 2 1 2 1 2 1 1 2 1 1 1 1 1 1 2 1 1 2 1 1 1 1 1 1 2 1 1 2 2 1 1 2 1 2 1 2 2 2 1 1 1 1 2 1 1 1 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 1 1 2 2 2 1 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 2 2 1 1 1 2 2 1 2 2 1 1 1 2 2 2 1 2 1 2 2 2 2 1 1 1 2 2 1 1 2 2 2 1 1 1 2 1 1 2 2 1 2 1 2 2 2 2 1 2 2 2 2 2 1 2 1 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 1 2 2 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 1 2 2 1 2 1 1 2 1 1 1 2 2 1 2 1 1 2 1 2 1 1 1 2 2 1 2 2 2 1 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 2 2 1 2 1 2 2 1 2 1 1 1 1 1 1 1 2 2 1 2 1 2 2 1 1 1 2 2 2 2 1 2 2 2 1 1 2 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 1 2 1 1 1 2 1 2 1 2 1 1 1 2 2 1 1 1 2 1 2 2 1 2 1 2 1 1 1 1 1 1 1 1 2 2 2 2 1 2 2 1 1 2 2 2 2 2 2 2 1 1 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G T T G C A A G C T T C C T A G G T T G C T T C C A T C C T T G G A A G G A T C C A T C G A T G G A T G C A A C C A A G C T T C G T A C G A A G G A A G C T A G G T T G C T A C C T A G C A A C G A A C C A A G C T A G C T T G G A T G C T A G C T T G G A T G G A A C G T A G C T A G C A A C C A A G G T T G C A A C G A A C G A A G G A T G G A T C C T T G C A A C G A T G C T A C G A A C G A A C C T T G G T A C G A A G C T T G C T T C C A T G G T T C G A T C C A T G C T T C G T A C C T T C G T A C G T A C C T T G G T T C G T T G G A A G C T T G C A T G G T A G C T T C C T A G C A T C C A A G C A A G G A A G G A T C G T A G C T A G C A A G C T A C G A A G C T A G C A T G C T A C C A T G G T A C C T T G G A A C C T A G G A T C C T T G G T A G G T A C G T T G G T A C G T A G C T T G C A T C C A T G G A T C G T A G C A T C G T A C C A T C C A A G C T T G C A T G G T T G C T A G G T A C C T T G C T T G G T T C C T T G G T A C C A A G C T T G C A A G C A A C C A A G C A A C C A A G G T T C G T A G G A A G G T T C C T A C G A A G G T A G C T T G G A T G G T T G G A T C C T A G G A A G G T A C G T A C G A T C C T A G C T T C G T A C C A A C C A T G G T T G G T T G C A A G C A A C C T A C G T T C G A T G C T T C C A A G C A A G C T A G C T A G C T T C G A T C G A A C C T A C G A T C G A T G G T T G G A T G C T T C G T T G C T A G C A A G G T A C C T T C C T A G G T A C C T A C C A A G C T T G C T A C G A T G C A A G C A A G G A T G G T T C C A A C G A T G G T A C C A A C G T A C C T A C G T A G G A A C G A A G C T A C G A A G C T T G C A A C C T A G G A A G G T T G C A A C G A T C C T A G G T T G C A A C C A T G C T T C C A T G G T A G G A T G G T A C C T A G C T A G C T A C G A T G G T T C G T A G C A T C G T T G G A T C G A T C G A T C C T A C G A A G C T T G C T T G C A A C G T T G C A A G G T A G G A T G G A A C G T A C C T A C C A T G C T T C C T T C C A T G C A A G C A T G C A A C C T A C G T T G C T T G G A T C C T A C G A T C C T T G C T T G G A A G C T T C C T A G C T T G G T A G C T A C C A T G C A A G G T T G G A T G G T A G G A T G G A A C C T A C G A T C G T A C C A T C C T T C C T A C G T T C C T A G C T T G G T T G C T A G C T A G C T A G G T A C C A A G C T T C C T T G G T T G C A T G C A A G C A T G C A A G G T A C G A T C C A T G G T T G C A A G C A A C C T A C G A T G C A T C C A A G C T A G G A T G C A A C C A T G G A T C C T A C C A T C G A T G C T T C G T A G C A T G G A A G C A A C G T T C C T T C C A T G G T A G C A A C C T T C C T T G C A T G G T T G G T T C G A T C C T A G C A A C C A A G C A T G C A A G C T A C C A A G G T A C C T +A G G T A C G T A C G T T G C T A C G T A G C T A G G T A G C A T C C A A C G T T G C T T G C T A C G A A C G T T C C T A C C T A G C T A C C T T C C T A G C A T G G T T G C A T C G A A G G T A G C T T G C T A C C A T G C T A G C T A G G T A G C A T G C T T C G T T C C T T G C T T C G T A G G T T C C T T C C A T C C T A G C T T C C A A C C T T C G A T G G T A G C T A C G A T G G T T C G T A C C A A G C A A C G A T C G A A G G A T C C T A C C A A C G A T G C T A G C T A G C T A G G T T C C T A C C T A G G A T G G T A C C A A G C A T G G T A G G T A G C T T G C A T G G A T G G T T G G A A C C T A G G A A G C A A C C T T C C A A C G A A C G T A C G A T C C A T G G T A G C T A C C A A C G A A G G T A G G T A C G A T G C T T C G T T G C T T C G T A C G T T C G A A G G T T G G T T C G T T G C T T G C A T G C A A C C T T C G T A C C A T G G A A G G A T C C A A G G A A G G A A C C T A C C T A G G A A G G A A G C A T G C A T C G T T C C A T G C A T C G T T C C A T G C T T G C A T C C T T G G A A G G T A C G A A C G T T C G T A G C T A C G T T C C A T C G A T C G T T G G A A G C T T C C A T G G T A C G T T G C T A C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A T G G A A C C A A G C T A G C A A G G T T C C T T G C A T C G T T C C T A C C T A G G A A C C T A C G T A G G T T C G A T C C T A G C T A G G A T G C T T C C T T C C T T G C A T C C T A C C A T C C T T C C T T G G T A G G A A G C A A C C A T G G A T C G A T G C A T C C A A G C A A C C T T C C T A G C T T C C A T C G A A C C T T C C A T C G A T G C A T G G A A G C T A G C T T G C T A G C A T C C T A C C A A C C T A G G A A G C A T G C T T C C T T C C T A G G T T G C A T C C A A G C T T G G T T C C A A C G A A G G T T C C T A C G T T C C A A G C T T G G A A C C A T G G T A C C A A G C T T C G A T G C T T G C A T G G A A G C T T C G T A G C A A G G A T G C T T C C T T C G A A C C A T G G A A G G T A G G T A C G T A G G T A C C T A C G A T G G T A C G T A G G T A G C A T G G A A G G A T G G A T C C T A G C T T G C T T G C T T G C A A C G T T G C A A G G T T G C T A G G A A C G T A C G T A C G T A C C T A C C T T C C A T G C A A G C A T G C A A C C T T G G T A G C A A G G A A C G T A C G A A C C T T G C A A G C A A G C T T C C A A G C A A C C T A G C T A C C A T G C A A G G T T G G A T G G T A G G A T G G A A C C T A C G A T C G T A C C A T C C T T C C T A C G T T C C T A G C T A G C A A G C A T C C A A C G T A G G A A C C A A C G T T C C T T G C T T G C A T G G A A G C T T G C A A G G T A C C T A C G T T G C T T G C T A G C A T C C T A C G A T C G A A C C A A G C A T G C A T G C A A C C A T G G A T C G T A C C A A G G T T G C T A C C A A G C T T C C A T C C T T C C T T C C A A G C A A G C T T G C T T C G A A G G A A G G T T G G T T C C T T G C T A C G A A G C T T G C A A G C A T G C T A G G T A G C T A G G T A C C T CHA_3117 # subpop. label: 8 (internally 8) -2 1 1 1 2 1 1 2 2 1 1 2 2 2 2 2 2 1 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 1 2 1 2 2 1 2 1 2 2 2 1 2 2 2 1 2 1 1 2 1 1 1 1 2 2 2 2 2 1 2 1 2 2 1 1 2 2 2 1 2 1 2 1 2 2 1 1 2 1 2 2 2 2 1 1 1 1 1 1 2 1 1 2 1 1 2 1 2 1 2 2 2 2 1 2 1 1 2 2 1 1 2 2 1 1 1 1 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 2 1 1 1 1 2 2 1 2 2 2 1 1 1 1 1 1 2 1 1 1 2 2 1 2 2 1 2 2 1 1 2 1 1 2 1 1 2 1 1 2 2 1 2 1 2 1 2 1 2 1 2 2 2 2 1 1 1 2 2 1 2 2 1 2 2 1 2 1 2 1 2 2 2 2 1 2 2 2 2 1 2 2 2 2 2 1 2 1 1 1 1 2 2 1 2 2 2 2 2 2 2 2 2 2 1 2 1 2 1 2 2 2 2 2 2 2 1 1 1 2 1 2 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1 2 1 1 2 1 2 1 1 1 2 2 2 1 2 1 2 1 1 1 1 1 1 2 1 2 1 2 2 1 2 2 1 1 2 2 2 2 2 2 1 2 2 2 1 1 2 2 1 2 2 2 2 1 1 2 2 2 2 1 2 1 2 1 2 2 2 1 2 1 1 2 1 2 2 1 2 2 1 1 2 1 2 2 2 2 2 2 +A C G A A C G T A C G T A G C T A C C T A G C T A G C T A G C T A C C A A G G T T G C T T G C T T G G A A C G A T G C T A G G T T G C A T G C T T G G T T G C A T G G T A G C A T C G A T G G A A C G T T G G T A G C A A C G T A C G T A C G A T G G A A G G A A C C A T G C A A G G A T C C T T G C T T C G A T C C A T C C T T G C A A G G A A C G T T C C A T G C A A C C A A C C A A G C T T C G T A C C T T G C A A C C A A G C T T G C T A C C T A G C A A C G A T G C A A G C T A G C T A G G T T G G T A G C T A G G A T G G T A C C T A G C T A C G T A C G A A G G T T C C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A G G A T G C A T C C T A G G T A G C A A G G T A C C T A C G T A C G A T C C A A C G T T G C T T C G T T C G A T C C T T G G T T C G A T C G A A G C T T G C A T G C T A G C T T C G T A G C A A G G A A G G A T C C T A G G T A C G T A G C T A G C T A G G T T G G A A G C A A G G A T C G T A C C A T G C T A C G T T G G A T C C T A G G T A G C A A C G A A C G T A G C T T G G T T G C T A G C A T G G T A G G A T C G A T C C T T G G A A G C T A C G A T G C A A G G T T C G T T C G T T G C A A C G T T G G A T C C A A G C T T C C T T G G T A C C A A G C A T G C A T C C A T C C A A C G T A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G A A G C T T C G A T G C T T G G A T G C T A G G T A G G T A C C T A G C A A G C A A C C T T G C T A G C A T C C T T C G A T G G T T G G T T G C A A C C A T G G A T C G A T C C A A C C A A G C A A G C T T G C A T G G T T C G T A G C A A G C T T C G A T C G A T C C A T G G A A G C T T C C T T G C T A G G A T G G A A C C T T C C T A G G T A C C T A C C A A G C T T G C T A C G A T G C A A G C A A G G A T G G T T C C A A C G A T G G T A C C A A C G T A C C T A C G A A C G A A C G A A G C A A C C T T G G A T G C A T C C T A C G A A G G T T G C A A C G A T C C T A G G T T G C A A C C A T C G A A C C A T G G A A G G T T G G T A C C A A C C T A C C T T C G A T G C A A C G T A G G A T C G T T G G A A G C T T C G A A G C A A G G T A C G A T G C T A G G A T G G T A C C A T G G T T G C T T C G A A C G T A C C T A G C T A G C T T C C T T C C A T G C T T C G T A C C A A C C T T G C T T C G A T C G T T G C T T C G A T C C A T G G A A G G A T G G A A C G T A G C T T C C A T G C A T C G T T G C A A G G T T C G A T G G A A C C A T G C T T G G T T G C A A G C A A C C A T C C T T C C T A C G T T G C T A G C T A C G T T C G T T C C A A C G T A G G A A C C A A C G T T C C T A G C T T G C T T C G A A G C T A G C A A G G T A C C T A C C T T C G T T G C A A C C A A C C T A G C A T G C A T G G A A G C T A G C A T G C T A G G T T C G T T C C T A C C T T C C A A C C T A G C A T C C T A G G A T G C A T C C A T C C A A C G A T C G T T G C A A C G T T C C T A G G T A G G T T G G T T G C T A C G A T G C T A C C A A G C A A C C A T G C T A G C A A G G T A C C T +A G G A A C G T A C C T A G G A T G G A A G C T T G G T T G C T T C C A A C G A T C C T T G C A A C G T T C G A T C C T A G G T A G C T A C C T T G C T T G C A T G G A T C C A T C C T T G G A T G C T T C G T A G G T T C C T A C G A A G C T T G C A T G C T T C G T T G C A A C C T A C G A A G G T T G C T T C C A T C C T A G C A A G G A T G C A T C C T T G G A A G C T A G C A A G C T T C G T T G G T A G C A A G C A A G G T A G C T A C C T A G C A A G C T A G C A A G C A A C G T A G G A T C C T A G C T T C C A T G G A A C C T T G C T A G C A A C C A A G G T T G C T A C G A A C G T A G G A T G G A T G G T T G G T A C C T T G G T T C G A A C G A A G G T A C C A A C G A A G G T A G C A T C G T A G C A A C C A T G G A T G C A T C C T A G C T T C G T A C G A A G C A A C C T T G G T T C G T T G C T T G C A T G G T A G C T T C G T A C C A A G G A A G G A T G G A A G C A T C G A A C C A T C G T A G G A A C G A A G C A A C G A T G G T A C C A T G G T A C C T T G G A T C C A T G G T A G C T T G G A A G C T A G G A T G G A A C C T A G G A A C G T A G G T A G G A A G G A T G G A A G C T T C G A T G G T A C C T T C G T T C G T T G C A A G G T A G G T T G G T A G G T T C C T T G C T T C C A A G G A T G C A A C G A A C C A A G C T A G C A A G G T T C C A A C C A T G G T T C G A A C G T A G G A T C C T T G G A T G G A T C G A T C C T A G C T A G G T A C G T A C G T T G C A A G C T A G G T A G C T T C G T T C C A T G G T T G G T T G C T A C C A T C G T A G C T A G C A T C C A A G C A A G C T A G C T A G C T T C G A T C G A A C C T A C G A T C G A T G G T T G G A T G C T T C G T T G C T A G C A A G G T A C C A A C C T A G G A A G C A A G C T T C C T T C C T A G G T A G C T T C G T A G C T T G G T A G G A T G G A A G C T T G C T A G C T A G C A A G C T A G G A A C G A A G C T A G G A A C C T T G C T A C C T A C G A T G G T T C G T A C G A A C C A A G G A T G C T T C C T T C C T T C C A T C C T T G G T A G G T A C C A A G G T T C C T A C G A T G G A T G G T A G G T A G C A A C G A T C G A T G G A A C G T A G G T A C G A T G C T T G C A T G G A A C C A T G G T A G G A T G G T A C G A A C G T A G C T A G C T A C C T T C C T T G C A T G G T A C C A A G C T T G C T T G C T A G G A A C C T T C C A T G G A T G C T A G C A A G G A A C C A A G C A A C C T T C C A T C G T T G C A T G G A T C C A T C G A A G G A A G C A T G G A T G G A A G G A A C G T T C C T T C C T A G G T T C C T A G C T T G C T T G C A T G C T T C G T T C C T T G C T T C G A A C C T T G C A A G G T A G G T A G C T A G C A A G G A T C G A T C C A T C G T A G C A A G G T A C G T A C C A A C C A A C C A A G C A T C C A T G C A T G C A A G C T T C C T A C C A T C C A T G C T A C G T A G C A T G G A A C C A T C C T A C C A A C G A T C G T T G G T A C C T T C C T A G C T T G C T T C C T T G C T A C G T A G C A A C C A A G C A A C G T T G C A A G G A A C C T A G C T CHA_3118 # subpop. label: 8 (internally 8) -2 2 2 2 2 1 1 2 2 1 1 2 2 2 2 2 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 2 1 2 2 1 1 1 1 1 1 2 2 2 1 2 2 1 2 2 1 1 2 1 1 2 1 2 2 2 2 1 2 2 2 2 2 1 2 2 2 1 1 2 2 2 2 1 2 2 1 2 1 1 1 1 2 1 1 2 1 1 2 2 1 2 1 1 2 2 1 1 2 1 2 2 2 1 1 1 1 2 2 1 2 2 2 2 1 1 2 1 2 1 1 2 2 2 1 1 1 1 1 2 2 1 2 2 2 1 2 2 2 2 1 2 1 2 1 1 2 2 1 1 2 1 1 1 2 2 1 2 1 1 2 2 1 1 1 1 2 1 1 1 2 2 1 2 1 1 1 2 2 2 2 1 2 1 2 2 2 2 1 1 1 2 1 2 1 2 1 2 2 2 2 2 2 1 1 2 1 1 2 2 2 1 2 1 2 1 2 1 1 1 2 1 1 2 1 2 2 1 2 2 2 1 2 1 1 2 2 2 1 2 1 1 2 2 2 1 2 2 2 2 1 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 1 2 2 1 2 1 2 2 2 2 1 2 2 2 2 1 1 1 2 2 1 1 2 2 1 1 1 2 1 1 1 2 1 2 1 2 2 1 2 1 2 1 1 1 2 2 2 1 1 1 2 1 1 1 2 1 1 1 2 2 2 1 2 1 2 1 2 2 1 2 2 1 1 2 2 2 1 2 2 1 2 2 2 2 1 2 1 1 1 1 1 1 2 1 2 1 2 2 1 2 1 2 2 1 2 1 2 2 2 2 1 1 1 1 2 2 1 2 1 2 1 2 1 2 1 1 2 2 2 2 1 2 2 1 1 2 1 2 2 2 2 2 1 1 2 2 2 2 2 1 2 1 1 1 2 2 1 1 1 1 2 2 1 1 1 2 2 2 1 1 2 1 2 1 1 1 1 2 2 2 1 1 2 1 1 1 2 2 2 1 2 1 1 1 1 2 2 2 1 2 2 1 1 2 2 1 2 1 2 2 1 1 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 1 1 1 2 1 1 2 2 2 1 1 1 2 1 1 2 1 1 2 2 2 2 2 1 2 2 1 2 1 2 1 1 2 1 1 2 2 1 1 1 2 1 1 1 1 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G T A G G T T C C T T G G A T G C A A G C A T G G A A C C A T C G A T C G A T G C A T G C A A C C A A C C A A G C A T G C T T C G T T G C A T C G T A C C A T C G A T G G A T G G T A G C T T C C A A G C T A C G A T G G A A C C T T C C T A G G A A G C T T C C A A G C T T G C T A G G T A G C T A G C A A G C T T C C T T G G A T G G A T G G T T C G T A C G T A C C T A G C T A C G A A G G A A G G A A G C T T G G A T C G A T G C T A C G A T C G T T C G T A C G A A C C T A G G A T G C T T C C A T G C T T C C A T G G A A G G T T G G T A C C A A C C T A C C T T C G A T G C T T C G T A G G A T C G T A C G A T C G T T C G T A C G T A C G A A G C T T G C T T G C A T G G T A C C A T G G T A G G A A C G T T C G A A C G T A C C T A C C A A C C T T C C A T G C T T C G T A C C A A C C T T G C T T G G T A G G T A G C T A G C A T C C A T G C T T G G A A G G A A C C A T G C A A C C T T G C A A G C A T C C A A G G T T G G A A G G T A G G A T C C A T G C T T G C A A G C A A C G A T C C T A C C A A C G T T G C A A C C T A C C T T C G T T G G A A G C A T C C T A G C T A G C T T C C T A G C A A G G T A G G T A G C T A G C A A G G T T C G A T C C A T C G T T G C T A C C A A C C T A G C A T G C A T G G A A G C T A G G T T C G A A C G T T C G T T C C T A C C T T G C T T G C T A C C A A G C A T G C A A G C A T G C T T C C T T C C T A G C T T G C A A C C T T C C T T G C A T G G T T C G T T C G A T C C T A G C T T G C A A G C A T G C T A G G T A G C T A G G T A C C T +A G C T A C G T A C C T T C C T A C G T A G G A T G G T T C G T T C C A A G G A T G C T T G C T A C G T T C G A T C C T A C C T A G C T A C C T T G G A A C C T T G G T T C C A A C C A T G G T T C G T T G G T A C C T A C G A A C C T A C G T A G C A T G C T T C G A T G C A A G C A A C G A A C G T T G C T A C C A T C C A A G C T T C C A A C C T T C G A T G G A A G C A A C C A A G C T T C G T A C G A A G G A A G G A T C G A A G G A T C C T A C C A A C G A T G C T A G C T A G C T A G G T T C C T A C C T A G G A T G C T A C C A A G C A T G G T A G G T A G C T T G C A T G G A T G G T T G G A A C C T A G G A A G C A A C C T T C C A A C G A A C G T A C G A T C C A T G G T A G C T A C C A A G C A A G G T A G C A A C G A T G C A T C C T A G C T T C G T T C G T A C C A A G G T T G G A T C G A A G C T T G C A T G C A T G C A T G G A A C C A A G G A A G G A T G G T T G C A T C C A A C C T A C G T T C G T A G C A A G C A T G G A T G G T A C C A T G C A T C G A A G G A T G C A T G G T A G C A T C C T A G G T A C C T T G G T T G C T A G C A A C C T T C C A T C G A T C C T A G G A T G C T T C G A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A G G A A G G A T G G A A G C A A C G A A G C T A G C A A C G A T G C T T G C A T C G T T C C T A C G A A G G T T G C T T C G A T G G T T G G A T G C T A C G T A G C A T G C T T G C A A G C T A G C T T G C T A G C A T C C T T G G A T G G T A G G A T G G A A C C A T C G A T C G A T G C A T C C A A C C A A G C T T C C T T G G T T C C A T G C T A C G A A C G A T C C A T C C A T G G A T C C A A C C A A C G T T G C A A C C A A C C T T C C T A G G T A C G T T C C A A C C A T C C T A G C T A C G A T C G T A G C T T G G T T C C A A C G A A G C A T C C T A C G T A C C A T C C T A C G A A G G A A G C T T C G T T G C T T G C A T C C T A C G A T G G T T C G T A C G A A C C T A G G A T C C T A C G T T G C A T C C A T G G T A C G T T G G T A C C A A C C T A C C T A C G A T G G A T C G T A G G T A C C T A C G A T C G A T C G A A G C A A G G A A C G A T G C T T G C A T G G A T G C A T G G T T G C A A G G T A C G T A C C T T G C T T C C A T G C T T C C T T G C A T G G T A C G A A C C T A C G T T G C T T C G T T C C T T C G A T C C A T G G A A G C A A C G A A C G T A G C A A C C T T C C A T C G T T G C A T G G A T C G A T G G A A C C A T G C A T G G A T G G A A G G T A C G T T C C T T C G T A C G T A G C T A G C T A C G T T C G T T C C A A C G T A G G A A C C A A C G T T C C T A G C T T G C T A G G T A G C T A G C A A G G A A C C T A C C T T C G T A C C A A G C A A C C T A G C A T C G A T C C A A G C T A G G T A C C A T C G A T G G A T G G A A C G A A G G T A G G T A G C A A G C T T G G T A C C A A C G A T C C A A C C A T C G T A G C A A C C T T G C T T G C T T G C T T C C T T G C T A C G A A G C A A C C A A G C A T G C A A G C T A C C A A G G T A C C T CHA_3119 # subpop. label: 8 (internally 8) -2 2 1 2 1 2 1 1 1 2 2 2 1 2 2 2 2 1 2 2 2 2 2 2 2 2 1 2 2 2 1 1 1 1 2 1 2 2 1 1 1 2 2 2 1 2 2 2 1 2 1 1 2 2 1 1 1 2 2 2 2 1 2 2 2 2 2 2 2 1 2 2 1 1 2 2 1 2 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 2 1 1 1 2 1 2 2 1 2 2 2 1 1 1 2 2 2 1 1 2 2 2 1 1 1 2 2 1 2 2 1 2 2 1 2 1 1 2 2 1 2 1 2 2 1 1 1 2 2 1 1 2 1 2 2 1 2 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 2 1 2 2 1 1 1 1 1 2 1 2 2 2 2 2 1 2 2 1 2 2 2 2 2 1 1 2 1 2 1 1 2 2 2 1 2 2 2 1 2 2 1 2 2 2 2 2 2 1 1 2 2 2 2 1 2 1 1 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 2 2 1 2 1 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 2 2 1 2 2 2 2 2 2 1 2 1 2 1 2 2 1 2 1 2 2 1 2 1 1 1 2 2 2 2 2 2 1 1 1 2 2 1 2 1 2 2 1 2 2 1 2 1 1 1 1 2 2 2 2 1 1 1 2 1 1 1 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C T A G C A T C G A A G C A T G G T T G G A T C C T A G G T T G C T A C G T A G C T A G C T T C G A A G G A A G G A A C G T T G C T T G C A A C C T A C G T A G G T T G C T A G C A A C G T T C C A A C G T T C C T T C G A A G C A T G G T A G G A T G G T A C C A A C C T A C C T A G C T A C C T T C G T A G G A T C G T T G G A A C G T T G C T A C G T A C G A A G C T T G C T T G C T T G G A T G C A T G G T A G G A A G C T A C G T A C C T T G C A T C C A A G C T T C C T T G C A T G G T A C G T T G C T A C G T A G C A A G G T T G G A T C G A A C C T T G C A A G C A A G C T T C C A A G C A A C C T T G C A A G C A T C C A A G G T T G G A A G G T A G G A T C G A A C C T A C G A T C G T A C C T T C C T T C G T A C G T A C C A A G C T T G C T T C G T T G G A A G C A A G G T A C C A A G C T T C C T T G C T T G C T A G C A A G C T A G G A A G G A T C G A T C C A T C G T T G C A A C C A A C C T A G C A T G C A T C G A A G C T A G G A T G C A A C C A T G G A T C C T A C C T T C G T A G G T A G C A A G 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A G G A T G C T A C G T T C G A A G C T T G G T A C C A T G G T T G C T T G C A T G G A T C C A T G G A A C G T T C G T T G G T A G C A T C C T A C G T A G G T A G G A T G C T T C G T T G G T T G C T T C G T A G C T T G C T A C C A T C C A A G C T T C C A T G C A T C C A T G C T A G C T T G C A A G C T T C G T T G G A A G C A A G G A A G G A T G C T A G C T A G C A A C G A T G C T A G C T A G C T A G G T T C C T A G C T T G G T T G C T A C G T T C C A A G G A A C G A A G C T T G C A A C G A A G G T A G G A T G G T T G G A T G C A T C C T T G G T T C G A A C G A A G G A T G C T T G G A A G C T T G G T A C G A T G G A T G G T T C G A T C G T T C C T A G C T T C G A A G G T A G G T T C G T T C G T A C G A A G C T T G C A T G G T A G C T T C G T A C C A T G G A A G C A A G G A A G G T T G G A A C C T A C C T A G G T T C C A A C G A T G C A T C G A A C C A T G C A A C G T T C C A T G C A T G C A T C C T T G G A A G G T A C C T T G G T T G C T A G C A T G C T T C C A T G G A T C C T A G C A T C C T A C C T A G C T A C G A T G G A T C G T A G C A A C G T T G G A T C C T T C C A T C C T T C G T A C C A A G G A T G C A A G G A A C C A A G C T A G G T T C G A T G C T T G G A T C G T T C C T A C G A A G G T A G C T T C G A T G C T T C G A T C C T A G C T A G C A T G C T T C C T T C C T A C C T T G C T A C C A T C C T T C C T T G G T T G G T T G C A A G C T A C G T T C G A T G C A T C C A A C C A A C C A A G C A T G C T T C G A T C G A A C C T A C G A T C G A T G G T T G G A T G C T T C G T T G C T A G C A A G G T A C C T T C C T A G G T A C C T A C C A A G C T T G C T A C G A T G C A A G C A A G G A T G G T T C C A A C G A T G G T A C C A A C G T A C C T A C G T A G G A A C G A A G C T A G G A A G C T T G C T A C C T A C G A T G G T T G C T A C G A A C C A A G G A T G C T T G C T T G C A T C C A T G G T A G G A T G G T A C C A A G G T T C C T A C G T A C C A T G G T T C G A T G C A A G G A T C G A T G G A T C C A A G G A A C G A T G C T T G C A T G G A T G C T A G G T A G G T A G G T A C G A A C C A T G C T T C C A A C G T T C C T T G C A A G C A T G C A A C C T T G C T T G C T T G G A T C C T A C G A A C C T T G C A A G C A A G C T T C C A A G C A A C C T T G C A A C G A T G C A A G G T T G G A A G G T A G G A T G C T T G C T T G C A A G G A A C G A T C C T T C C T A C G T T G G T A G C T A C G T T G G A T G C A T C G T A G G A A C C A A C G T T C C T T G C T T G C T A G C A A G C T A G C A A G C A A C G A T C C A T C G A A G C T A C G A A C C T A C C A T G C A T G C A A G C T A G G T A C C A T C G A T G G T T C G A A C G T T C G T A G G T A G C A T G C T T G G A A G C T T G C T T C C A A G G T A G G T T G G T A C C T T C C A A G C T T G C T T G C T A G C A T C C T A G C A T C C T A G G T A C C A A G C T A G C T A G G T A C C T +A G G T A C G T A C C T A G C T T G G A T G C T A G C T A C G T A C C A A C G A A G G A T G C A A G G T T C G A A G G T T G G T A G C T A C C T T C C T T G C T T G C T T G C A T C C T T G G T T G C T T C C A A G C A T C G T A G C T A G G T A G C A T G C T A C C A T G C A A G C T T C G A A C G T T G C A T C C A T C C A A C C T T C C A T C G T A C C A A C G A A G C T A C C A A G C T T C G T A C C T T G C T A G C T A G G T T G C T A C C T A G C A A C C T A G C A A G C A A C G T A C G A T C C T A G C A A G G T A G G T T C C T T C C A T G G A A C G A A G G T T G C A A C G A A G C T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A T C C T T G G T A C G A A G C T T G G T A C G T A G C T T G G T A C G A T C C A A C C T A C C A T C G A A G C T T G G A A C G T T G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G G A T G G T A G G A A G G A A C C T A C C A A G G A A G G A A C C A T G C A T C G T A C C A T G C T A C G T T C C A T G C A A G G A T C C T T G C A T C G A T C G T T G C T T G C T A G G A A C G T A G G A T C G A T C C T T G G A A G C T T C G A A C G T A C G T T G C A T C G A A C C T A G G T A G G T T G G T A G C A T C C T T G G T A C C A A G C A T G C A A G C A A C C A A C C A A C C A A C G A T G C T T G C A T C G T T C G A A C G A A G G T T G C T A C G T A G G T T C G A T C C T T G G T A G G T A C G T T G C A A G C A A G C A T C G A A C C T T C C T T G G A A G G T A G G A T C C A A C C A T G C A T C G A T G C A T C G A A G C A A C C T T G C T T G C T T C C A T G G T T C C T T C G A T C G A T G G A T G G A A G G T T C C A A G C T A C G A T C C A A C C T T G G A A G G T A C C A T C C A A C C A T C C T A C C T T G C A T C G A A G C A T C C T T G C A A C G A T C G A T C C T A G C A A G C A A G C T A C C T T C C T A G G T A C C A A C C T T C G A T G C T T C G A T G G T T C G T A C G A A C C T A G G A T G C T T C C T T C C T T C C A T C C T T G G T A G G T A G C T A G G T A C C T T C G A T G C A A C G T A G G T A G C A T G G A A G G A A C G T T C C T A G G A A C G A A C C T A G C A A C G T A C C A T G G T A C C T A G G T A C G A A C C A T G C T A C C T T C C T T C C A T G C A A G C A T G C A A C C T A C G T A G G A T G G T T G C T T C C T T C G T T G C T T G G A A G C T T C C T T G C T T G G T A G G A A G C A T G C T T G G T T G G T T G G T T G C A A G C T T G G T A C C T T C G T A C C T T G C T T C C T A C G T A G G A A G C A A G G T T G G A T G C A A G C T T C C T A C G T T C G T T C C T A C C T T C G A T C G T A G C T A G C A A G C A A G G A T C C A T C G A T G C T A C G A A C C T A G C A A C C A T C C A A G C T A G G A T G C A A C G A A G G T T C C T A C G A A G G T A G C T A C C A A G C A T G G A A G C A A C G T T C C T T C C A A G G T A G C A A C C T T C C T T G G T T G G T T G C T A G G A A C G T A G G T A G C T A G C A A G C T T G C T A C C T A G G T A C C T CHA_3123 # subpop. label: 8 (internally 8) -2 2 2 2 1 2 1 1 1 2 2 2 1 1 2 2 2 1 2 2 1 1 1 2 2 2 1 2 2 2 2 1 1 2 2 1 2 2 1 2 2 2 2 2 1 2 2 2 2 1 1 2 1 1 1 1 2 2 2 2 1 2 1 2 1 1 2 1 1 2 1 2 1 2 2 2 1 2 2 1 1 2 1 1 1 1 2 1 1 2 2 2 1 2 1 2 1 2 2 2 1 2 1 2 2 1 1 1 1 1 2 2 2 2 2 2 2 1 1 2 2 2 2 1 1 1 1 2 2 1 1 2 1 2 2 1 2 2 2 1 2 1 2 2 2 2 1 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 2 1 1 2 1 1 2 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G T A C G A T C G T T C G T A C C T A C C A A G C A A G G T A G C A A C G A A G C T T C C T A C C T T C G A A G G T A G G T T C G T T C G T A C G A A G C T T G C A T G C A A G C A T C G T A G C A A G G A A G G A T G G T T G C A T C G A A C C A T C G T A G G A A C G A A G C A A C G A T G C T T G C A T G C A A C G T T C C A T G C T T G G T A G C T T G G A A G G T A G C A T G G T T G C T T G C T A G G A T G G A A G G A A G G T T G G A T C G T A C G A T C C T A C G T T G C T A C G T T G C T A G G T T G G A T C C T T G G A T C C T T G G T A C C A A G G A T G C A A G G A A C C A A G C A A G C A A G C T A C C T A G C A T G G T T G G A A C G A A G G T A G C A A C G T A G G A T C G A T C C T A G C T A G G T A C G T A C G T T G C A A G C T T C G T T C C A A C C A T G G T T G G T T G G T T G C A A C C A T C G A A G C T A C G A T C C A A C C A A G C T T C C T T G C T T C G A A G C T T C C T A C G T T C G A T G G A T G G T A G C A A G C A A C G T T G C A A G G T A C C T A C C T A G G T A G C A T G C T T C C A T G C T A G G T A G C A T C G A A G C A T G G T T G G A T C C A T C G A T C C T T C G T A G C A A C G T A C G A A G G A A G C T A C C T T G C T T G C A T C C T A C G A T G G T T G C T A G C A A C C T A G G A T C G T T G C T T C G A A C C A T G G T A C G A T G G T A C C A A C C T A C C T A C G A T G G A T C G T A G G A T G C A T G G A T C G T A C G A T C C T A C G A A C C T A G C T A C G A T G G A T G C A T C C A A G G A A G C T A C C A A C G T A G C T A G C T A C C T T C G T A G C T T C G T A C C A A C C T A C G T T G C T T C G T T C C T T C C A T C C T T G C T A G G A A G C T A G C A A G C T A C C T T G G A A C C A T C C A A G G T T G C A A G G T A G G A A G C T T G C T T C G T A C G T A C C A T C C T T C C T A C G T T C C T T G C T A G C A A G C A T C C A A C G T A G G A A C C A A C G T T G G A T C C T A C G T A C G T A G C T T G C A A G G A A C C T T C G T T C G T T G C A A G C A T C C T A C G A T G C A T C G A A G C T A G G A T G C A A C C A T G G A T C C T A C C T T C G T A G G T T C C A A G C A T G G T A G G A A C G T T C C T A C C A A G C T T G C T T G G T T C C T A G C T T G G T T C C T A G C A A C C T A G C A A C C T A G C T A C G T A G G T A G G A A G G T A C C T +A G G A A C G T A C C T A G C A T G C T A G C T T G G T A C G T T C C A A C G A T G C T T G C T T G G A A G G A T C G A A C C A T G C A T C C A A G G A A C C T T G G T A G C A T C G T T G G A A C G T T G C A A G C A A G G T A C G T A C G T A G G A T G C T T C G T T C G T T G C T T C G T A G G T T G C T T C C A T C C T T G G A A G G A T C C A T C C A T G G A T G C A A C C A A G C T T C G T A C G A A G G A A G G A T C G A A G G A T C C T A C C A A C G A T G C T A G C T A G C T A G G T T C C T A C C T A G G A T G G T A C C A A G C A T G G T A G G T A G C T T G C A T G G A T G G T T G G A A C C T A G G A A G C A A C C T T C C A A C G A A C G T A C G A T C C A T G G T A G C T A C C A A G C A T G G A A G G T A C G A T C G A A C C T T G G T T C G T A C G A A G C A A C G T T G G A T C G T T C C T T G C A T G C A A C C T T C G T A G G A T C G A A G G A A G G A A G G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A A C C A A C G T T G G A T G C T A G C A T C C T T G G A A G G T A G C T T G C T A C C T A G C A A G G T T C C A T C G A T C G T A G C A T C G T A C G A T C C T A C G T T G C T T C G T T G C A A C G T T G G A T C C T T C C A T G G A A G G T A G G A A G G A T G G A A G C A A C C A A C C A A C C A A C G A T G C T T G C A T C G T T C G A A C G T A G G A A G C T T C G A T G G A T C G A T C C A A C C T A G C A A C G T A G G A A G C A A G G T T G G A T G C A T C C A T G G A A G G T A G G A A G C A A C C A T G C A T G G T T C C A A C C A A G C A A G C T T G C A T G G T T C G T A G C A A G C T T C G A T C G A T C C A T G G A A G C T T C C T T G C T A G G A T C C T A C C T T C C T A G G T A G C A A G G T T G C T T G C T A C C T A G C A T G C A T G C A T G G T T G G A A C G A A G G T T C C T A C G T A G C A T G C T A C G A A G G A T G G T A C C T T G C T A G C A A C C T A G G T T G G T T G C T A G C A A C G T T C C A T G C T T C C A A G C A T C C T A G G T A C G T A G G T A C C A A G G T A C C T A C C T A C C T T C G T A G G T A G C A A C G A T C G T T G G T T C C T T C G A A G C T T G C T A G C A A C G T T G C A A G G T A G G A A G G T A C G T A C G T A G C A T G C A T G C T T C C T T G C A T G G T A C C A A G C T T G C T A G G A T C G T T C C T T C C A T C C T T G C T T G G A A G G A A C C T A G C T T G G T A G C A T C G T T G C A A G G T T G C A T G C T T G C T A G C T A G G A T C G A A G G T A C G T T C C T T C C T A C C T T G C T T G C T A C G T T G C T A G G A A G C T A C G T T C C A T C G T T G G A A C C A A G C T A C G T A G G A T G C A T G C T T G C T T C C A T G G T T G C T T C G T A C C T A G G A T C C A T C G A A G C T A G G A T G C T A C G A T G G T T G C T A C C T A G G A A C C T A G C A A G C T T G G A T G C A T C G T A G C T A C C A A G C T T G C T A C G T T C C T A G G T A G G T T C C T A G G A A C G A A G G T A C C T A G G A A C C T A G G T T G C A A C C A A C G T CHA_3125 # subpop. label: 8 (internally 8) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 2 1 1 2 1 2 2 2 2 1 1 2 2 2 1 1 1 1 2 1 2 1 1 2 1 2 2 2 1 2 2 1 2 2 1 1 2 1 1 2 1 2 1 2 1 2 1 2 2 2 2 2 2 1 2 2 1 1 1 2 2 2 2 2 1 2 1 2 2 2 2 1 1 2 1 2 1 1 1 1 2 1 2 2 1 2 2 2 1 1 2 1 1 1 2 2 2 2 2 2 2 2 2 2 2 2 2 1 1 2 1 1 1 1 2 2 1 1 1 1 2 1 2 2 1 1 2 2 2 2 2 2 1 1 2 1 1 1 2 1 1 1 2 1 2 2 2 1 1 1 2 1 1 2 2 1 1 1 2 2 1 2 1 2 1 2 2 2 2 1 1 1 1 1 1 1 1 1 1 2 2 2 1 1 2 2 1 1 2 2 1 1 1 1 1 1 2 2 1 1 1 1 2 2 2 1 2 1 2 1 1 1 1 2 2 1 1 2 2 2 1 2 2 2 1 2 1 2 1 1 2 2 2 2 2 2 2 2 1 2 1 2 1 1 2 1 1 2 1 1 2 2 2 1 1 1 2 2 1 1 1 2 1 1 1 2 2 1 1 2 1 1 2 1 1 2 2 2 1 1 1 2 2 2 1 1 2 2 1 2 2 1 2 1 1 2 1 2 1 2 2 1 1 2 2 2 1 1 2 2 1 1 2 2 2 2 2 1 2 2 2 2 1 2 2 1 2 1 2 2 2 1 2 2 1 2 2 2 2 1 2 1 1 1 1 2 1 1 1 1 2 2 2 2 2 1 2 2 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 2 1 2 1 2 1 1 2 1 2 2 1 2 1 2 2 2 1 2 2 1 1 1 2 1 2 2 2 2 1 1 1 1 2 2 2 2 2 2 2 2 1 2 2 2 2 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T C C A T C C T A G C T A G C T A G C A T G G A T C C T T C G A A C C T T C C T A G C T T C C A T C C A T C C A A G C A T C C A T G C A T C C T T G G T T G C T A C G A T C G A T C G T A G G A A G G A A G G A T C G A A G G A T C C T A C C A A C G A T G C A T G C T T G C T T G G T T C C T A G C T A G G T T G G A A C G T T C C T A C G A A G G A T G G A T G C A T G G A A C G T A G G A T G C T T C C T T G C A A C G T T G G T A C G T A G G A A G G A A G C T A C C T A G G T A C C A A G C A A G G T A G C A A C G A T G G A T C C T A G C A A G G A A G G T A G C A A G G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G C A A G G A T G G T A G C A T C G T A G C T A G C A A G C T A C G A A C C A A G G A T C G A T G C A T G C A A C C T T G G A T C C A A G C T A G C A A C G A A C G T A G G A T G G T T G C T A G C A T G G T A G G A T C G A T C C T T G G A A G C T A C G A T G C A A G G T T C G T T C G T T G C A A C G T T G G A T C C A A G C T T C C T T G G T A C C A A G C A T G C A T C C A T C C A A C G T A G C A A G G T T C C A A C C A T G G T T C G A A C G T A G G A T C C T T G G A T G G A T C G A T C C T T G G T A G G T T G G T T G G A A G G T A C C T A G C T T C C A A C C A T G G T T G G T T G G T T G C A T C C A T C G A A G C T A G C A T C G A A G C A A G C A A G C A T G C T T C G T T G C T A C G A T C C A T C G A T G G A T G G A A G C T A G C A T C C T A G G A T C C T A C G A A C C T T G C T A C C A T C C T T C C A T C C A A G C T A C G A A C G T T G C T T G G T T C C A A C G A A G C A T C C T A C G T A C C A T C C T A G G A A C C A A C G A A C G A A G C T T C G T A C C T A C G A T G G T T C C T A C G A A C C T T C C A A C G T A C C A T G C T T C C T A G G A A G G A A G G T A G C A A G G T T C G T A C G A T G G A T C G T A G G A T C G T T G C A T C C T T C C A T C C T A G G A A G C T T G C T T G C A T G G T T G C T A G G T A G C T A G G T A C G T A C G T A G C A T G G A T C C T T C C A T G C T T C G T A C C A A C C T T G C T A G C T T C G T T G C T A G C A T C G A T G G A A G C A A C G A A C C A T C C T A C C T T G G T A C C A A C G T T C C T T G C A T G G A A C C A A G C T T G G T A C C T A G C A A C G T T C C T T C C T A G G T A C C T T G G T T G C T T G C A A G C T A G C T A C G A A G G T T C G T T G G A A C G A A G C T A G G T A G C T A G C A A G G T A C G A T C C A T C G A A G C T A C G A A C C T A C C A A C C A T C C A T C C T A G G A T G C A T G G A T G G T T C C T A C G T T C C T T G G T T C C A T C G T A G G A A G C A T C C A T G C T A C C A T G C T T G C T T C G T T C C T A G G T T G C T T C C T A G G A A C G T A G C T T G C A A G C A T C C T A G C A T G C A A G C A A C G T +A C C T T G G A T G C T T C C T A C C T T C G T A G G A A G G A T G C A A G G T A G C T T G C T A C G T T C G A A G C T T G G T A G C T A C C T T C C T A C C T T G C T A G C A T G C T T G G T T C C T T C G T A G C A A C G T A C G T A C C A T G G A T G C T T C G T T G C A A G C T T G C A A C G T T G C T T C C A T C C T A G C A A G G A A C G T T C G A T G C T A G C T T G C A A G C T T C G T T G G T A G C A A G C A T C G A A G G A A C C T A C G A A C G A A C C A A G C T A G C T A G G T T G G T A G C T A G G A T G G T A C G T A G G T A G C A A C C A A G G T T G C A A C C A T G G T A G G T T G G T T G C T T G C T T C C A T C C A A C C T A G G A T C G A A G C A T C G A A G G T A C G T A G G T A C C T A G G T A C G T T G C A T C C T A G C T T C G T T C G A A G C A A C C T A G G A T C G T T C C T T G C A T G C A A C C A T G G A A G G A T C C A A G G A T C C T A G G A T C G A A C C T A C C T A G G A A C G A A G C A A G G A T C G T A C C A T G G T A C G T A C C A T G C A T G G A T C C T T G G T A G G T A G C T T G G A A C C T A G G A A C G T A G G A A G G A A G G A T G G A A G C T T C G A T G G T A C C T T C G T T C G T T G C A A G G T A G G T T G G T A G G T T C C T T G C T T C C A A G G A T G C A A C G A A C C A A G C T A C C A A G G T T C G T A G G A T C G T T C C T A C G A A G G A A G C T T C G A T G C T T G G A T G C T T G C T A G G T A C G T A G C A T G C A A C C T A G C T A C C T T C C T T C C A T G G T T G G A A G C T A G C T A C G A T C G A T G C T T C C A A C C A A G C T T C C T T G C T T C G A T G C A A C G A A C G A T C C A T C G A T G G T A G C T A C C T T G C T A C G A A C G T A C C T T C C T A G G T A G C A T G C T T C C T T C C T A G G T A G C T T C G T A G C A T G C A T G G T A C C A A C G A T C C T A G G T A G C A A C G A T C G A A G G A A C G T A C G A A G C T T G C A A C C T A G G A T G G T T G C T A G C A A C C T A G G A T G C T T C C T T C G A A C C A T G G A A G G T A G G T A C C A A C C T A C C T A C C T A C G A T C G T A G G T A G C A A C G A T C G A T C C A A C C A A G G A A C C T T G C T A G G A A C G T A C C A T G G T A G G A A G G T A C G A T C G T A C G T T G C A A C G A A G C T T G C T T C G T A C C A A G C T A C G T A G C T T C G T A G G T T C C A T C C A T G C T A G C A A G C T A G C A A G C A A C C T T C C A A C C A T C C A A G G T T G G A T G G T A G G A T G C T A G G A T C G A A C G T A C G T T C C T T C C T A G G T A C C T T G G T T G C T T G C A A G C T A G C T A C G A A G G T T C G T T G G A T C G A A G C T A C G T A G C T A G C A A G C A A C G A T C C A T C G T T G C T A C C A A C C T A C C A T C G A A C C A A G C T A G G A T G C A A C G A A G G T T C C T A C G A A G G T A G G T A G C A T G C T T C C A T C C T T C C T T C C A A G G T A G G T T G C A A C G A A G C A A G C T T G C T T C C A A G C T A C G A T G G T A C C A A G C A T C C T T G C A A G C A A C C T A G C A CHA_3128 # subpop. label: 8 (internally 8) -2 2 2 2 2 1 1 2 2 1 1 2 1 2 2 2 2 1 2 2 1 2 2 2 2 1 1 2 2 1 1 2 1 2 2 1 1 1 1 1 1 2 2 2 1 1 1 2 1 2 1 2 1 1 1 1 1 1 2 1 1 2 1 2 2 2 2 2 2 1 2 2 1 2 1 1 2 1 2 2 1 2 2 2 2 2 2 1 1 1 1 1 1 2 1 1 2 1 1 2 1 2 1 2 2 2 1 1 1 1 2 1 2 1 2 2 2 1 1 2 2 2 2 1 1 2 2 2 1 1 1 2 1 1 2 2 1 1 2 2 1 2 2 2 1 2 1 2 1 2 2 1 1 1 2 1 1 1 2 2 2 1 2 1 2 2 1 1 2 1 1 2 1 1 2 1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 2 1 1 1 2 1 2 1 1 2 2 2 1 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 2 2 1 1 2 1 1 2 1 1 2 1 1 2 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G A A G C T A G C T T G C T A G C A A C C T A C G A T G G T T C G T A C G A A C C T A G G A T C G T T G C T T G C A T C C A T G G A A G G T A G G T A C C A A G C T T C G T A C C A T G C T T G G A A G G T A G C A T C G A T C G T T C G T T C C T A G C T A G G A T G C T A C G A T G G T A C C A T G G T A G C T A G G T A C G T T C G T A C G T T C C T A C G T T C C T T G G A A G C A T G C A A C C T T G C T T G C A T G G T T G G T A C C A T C C T T C G A A G G A A G G A A C C T A G C T T G G T A G C A A C C A T G C A A G G T T G G T T G G T A G G A A G C A A C C T T G C A T C G A A C C T T G C T T C C T A C G T A G G A A G C A A G G T T G G A T G C A A G C T T C C T A C G T T C G T T C C T A C C T T C G A T C G T A G C T A G C A A G C A A G G A T C G T T C G T T G C T A C C A A C C T A C C T T C G A A C C A A G C T A G G A T G C A A C G A T G G A T C C T A C C A A G C T A G C T A C G A T G C A T G G T A G C A T C G A T C C A A C C A T C C A T G C T T C C T T G C T A G C T T G C T T C C T A G C T T C C A A G C T T G C A A G C A T G C A A G C T A C C A A G G T A C C T +A G G T A C G T A C G T T G C T A C G T A G C T A G G T T G G A A C C A A G G A T C C T T C G T A C G A A G G A A G G T T G G T T C C A T G G T T G C T T G C T T G G A T C C A T C C T T G G A A C G A T C C T A C C T A G G T T C G T A C C A T G G A T G C A T C G T T C C A A G C T T C G T A G G T T G C A T C C A T C C T T G G A A G G A T C C A T C C A T G C A T C C T T C C T T C G T T C G T T C G A A G G A A G C T A G G T T G C T A C C T A G C A A C G A T G C A A G C A A C G T A G G T T C C T A G C A T C C A T G G T A C G T A G C T T G G A A C G A A G G T T C C A A C G A A G G A A G G A A G C T T G C T T G C A T C C A T C C T A C G A A C G A A C G A T G C T A C C T A G G T A C C T T C C A T G G T T C G A T C C A T C G T T C G T T G G T T G G T A C G T A G G A A C G T A C G T T G G A A G C T T G C A T G G T T G C A T G C T A G C A A G G A A G C A A G G A A G G T A G G A T G G T A C C T A G G A A G G A A G C A T G C A T C G T A C C A T G G T A C G A A C C A T G C T T G G T A G C A A C G A A G G T A G C A T G G T T G C T T G C T A G G A T G G A A G G A T C G T A G C A T C G T A C C T A C G T A C G A T G G A A C C T T G C A A C G T T G G A T C C T T C C T T C G T A G G T A G G A A C G T A G C A A G G A T C C A A C G A A C C A A G G T T C G A T G C A T C G T T C C T A C C A A C G T A G G A A C G T A G C A T C G A T C C A T C C T A G C A A C G T A G C T T C C A T G C A T C G T A C G A T C C T T C C T T G G T T G G T T G C A A C C A T G G A A C G A T C C T T C C A A C C A A G C T T C C T T G C T T C G A T C G T T C C T A C G T A C C A A G G T T G G A T C C A A C C T A G G T T G C A T C C T A C C A A G C T T G G A A C G T A G C T T C C T T C C T A G G T A G C T A G C A A G C T A C G T A G G A T G G A T G G T A G C T A C G T T C C A A C G T A G G A A C C A A C G A A C G A A G C T T C G A T G C T T G G A T C G T T C G T A C G A A C C T A G G A T G C T T C C A T G C T T C C A T G G T A C G A T G G T A C C T A G C T A C C T A C G A A C G A T G G T A G G T A G C A A C G A T C G A T C G A T C C T A C G A A G C T T G C T T G C A A C G T T G C T A C C T T G C T A G G A A C G A A C G T A G C T T G C T A C G T T C C T T G C A T C G T T G C A A C C T T G C T A G C T T G G T T G C T T C G A A C C T T G C T A G C A A G C T T C C A A G C A A C C T T G C A A C G A T G C A A G G T T G G A A G G T A G G A A G C T T G G T A C C T A G C A A C G T T C C T A G C A A C G T T G G A A G C T A G C T T G G T T G C A A G C T A C G T A C C A T C G T T G G A T C C T A C C T A C G T A G C A T G C A T C G T A C G A T C C A T C G A T G C T A C G A A C C T A G C A T C C A T C G A T G C A T C C A T C C A A C G A A G C T T C C T A C G T A G G T A G G T A G C T A G C A T C C A A G C T T C C T T C C A A G C A A G C T T G C T T C G A A G G A A G G T T G G T T G C T T C G A T C C T A G G T A C C A A G G A A C G T A G C A T G C A A C C A A C G T CHA_3129 # subpop. label: 8 (internally 8) -2 2 1 2 2 1 1 2 2 1 2 2 1 1 2 2 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T C C T A G C A A C G T A G C T T C C A T G C A T C G T A C G A T C C T T C C T T G G T T G G T T G C A T C C A T C G A A G C T A G C A T C C A A G C A A G C T A G C T A G C T T C G A T C G A A C C T A C G A T C G A T G G A T G G T A G G T A G C T A G C T A C G A T C C T A C G T T G G T A G G T A C G T T C C A A C C A T C C T A G C T A C G A T C G A A G C A T G G T T C C A A C G A T G C A T C C T T C G T A G C A A G C T T C G A A G G A A G G T A G C T T G C T T C G T A C C T A C G A T G G T T C C T A C G A A C C T T C C A A C G T A C C A T G C T T C C A T G C T A C G T T G G T A C C A A C C T A C C T A C G A T G G A T C G T A G G T A C C T T G G A A G G A A C C A A G C T A C G A A G C T T G C T T G C A T G G A T G C A A G G T A G C A A G G T A C G T A C C A T G C A T G C T T C C T T C C T T G C A T G G T A C C A A G C T T G C T A G G T A G G T A G C T T C G A T C C A T G G A T G G A A G C T T C C A A G C T T G G T A G C A A C G A T G C A A G C A A G G A T G G T A G G A T G G A A G G A 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1 1 2 2 1 2 2 2 2 1 2 2 1 2 2 2 1 2 1 1 1 2 2 2 2 2 1 2 2 1 1 2 2 1 2 1 2 1 1 2 1 2 2 1 2 1 2 2 1 1 2 2 2 1 2 2 1 1 2 2 2 1 1 1 1 1 2 1 2 2 2 1 2 1 2 2 1 1 2 1 1 1 2 2 2 1 2 2 1 1 1 1 1 2 2 2 2 1 1 2 2 1 2 1 1 2 1 1 2 1 1 2 2 2 1 2 2 1 1 1 2 2 1 2 1 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 2 2 2 2 1 2 2 1 1 2 2 1 1 2 1 1 1 1 1 2 2 2 2 1 1 1 1 2 2 1 2 1 1 2 1 2 2 1 2 2 1 1 1 1 1 2 1 2 1 2 2 2 2 2 1 2 2 2 1 2 1 2 2 2 1 1 2 2 1 1 1 2 1 2 1 2 2 1 2 1 2 2 2 1 1 2 1 1 2 1 2 1 1 2 2 1 2 2 2 2 2 2 2 1 2 2 1 2 1 1 2 2 1 2 2 1 1 1 1 2 1 1 1 1 2 1 1 1 2 2 1 2 2 2 2 2 2 1 1 2 2 2 1 2 1 1 1 1 1 1 2 2 2 2 2 2 2 2 1 1 1 2 2 2 1 1 2 1 1 1 2 2 1 2 2 2 1 1 1 2 2 1 2 1 1 1 2 2 1 1 2 1 2 2 1 2 2 2 1 2 1 2 2 1 2 1 2 1 1 2 2 1 1 2 1 2 1 1 2 1 2 1 2 1 2 2 2 1 2 2 2 2 1 2 2 1 1 2 1 2 1 1 1 2 1 1 2 2 1 1 2 2 1 2 1 1 1 1 1 1 1 2 2 1 1 1 1 1 2 1 1 2 1 1 2 2 1 2 2 2 2 2 2 1 2 1 2 2 2 2 1 2 2 1 1 2 2 2 1 2 2 1 1 2 2 2 2 2 1 2 2 2 2 2 2 1 2 2 2 2 2 1 1 1 2 2 2 1 2 2 2 1 1 2 1 2 1 2 2 1 2 1 1 1 1 2 1 2 2 2 2 2 2 1 1 2 2 1 2 1 1 1 2 2 2 1 1 1 2 2 1 1 2 2 1 1 2 1 2 2 1 2 1 1 1 1 1 1 1 1 2 2 2 1 1 1 1 2 1 2 1 1 1 2 2 1 1 1 2 1 2 2 2 2 1 1 1 2 2 2 1 1 2 1 1 2 2 2 1 1 2 1 1 2 1 2 2 1 1 2 1 2 1 2 2 1 2 1 2 1 2 2 2 1 2 2 1 1 2 2 2 1 2 2 1 1 1 2 2 2 1 1 1 1 1 2 2 1 1 1 1 1 1 1 1 2 1 2 2 1 1 2 2 1 1 1 2 2 2 2 1 2 2 2 1 2 2 1 1 2 1 2 1 2 2 1 1 2 1 2 2 2 1 1 2 2 2 2 2 1 1 2 2 1 2 2 2 1 2 1 1 2 2 1 1 2 2 2 1 1 2 2 1 2 2 1 1 2 1 2 2 1 1 1 2 1 2 2 2 1 2 2 1 2 2 2 2 2 1 2 1 2 1 1 1 1 1 1 2 1 2 2 1 2 2 1 2 2 1 1 2 2 1 1 2 1 2 1 1 2 2 1 2 1 2 2 1 2 2 1 2 2 2 1 1 1 2 1 2 2 1 2 1 2 1 1 2 2 1 2 2 2 1 1 1 1 2 1 1 2 2 2 1 2 2 1 2 2 2 2 2 1 1 1 1 1 2 2 2 1 2 2 2 1 1 2 1 2 2 1 2 1 2 2 2 1 1 2 1 2 2 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 1 1 2 2 1 1 2 2 2 1 2 2 2 1 1 2 1 1 2 1 2 1 2 2 2 1 1 2 2 2 1 2 2 2 1 2 1 2 1 2 1 1 1 2 1 2 2 2 2 2 2 1 2 2 2 2 2 2 1 1 1 1 2 1 2 1 1 2 2 2 1 2 1 2 2 2 1 2 2 1 1 2 2 2 2 1 2 2 2 1 1 2 1 1 1 2 2 1 1 2 2 1 1 2 1 2 2 1 2 2 2 1 2 1 2 2 1 2 1 1 1 2 1 2 2 2 2 2 2 1 2 2 2 1 1 2 1 2 2 1 1 1 1 2 2 2 2 2 1 2 1 1 2 2 2 2 1 1 1 2 1 2 2 2 2 2 1 2 1 2 1 2 1 2 1 1 2 +A G C T A C G T A C C T T C C A T G G A A G G A T G C T A C G T A C C T A G G A T G C T T G C A T G C T T G G A A G C A A C C A T G C A T G G T T G G A A C C T T G C T A G C A T G C T T G G A A C G T T C G T A G C A T C C A T C C T A C C A A C C A T G G T A C G T T C C T T G C T T C C T A G C A T G C T A G C T T G C A A G C T T C C T A C G T T C C A T G G T A G C T A C G A T G G T T C G T A C C A A G G A A G C T A G G T T G C T A C C T A G C A A C G A T G C A A G C T A G C T A G G T T G C T A G C T T C C A T G G A A C G T A G C T T G G A A G G A A G G T T C C A A C G A A G G A A G G A T G C A A C C T T G C A A C C A T G C T A G C A A C G A A C G A A G C A A C G A A G G T A C G T A G G T A C C T A G G T A C G A T C C A A C G T T G C A A G G A A G G T A G G T T G G T T C G T A C G A A G C T T G C A T G G T A G C T T C G T A C C A A G G A A G C A A G G A A G G T T C G A A C C T A G C T A G G T T G G A A G C T A G C A T G C T A C C A T G G T A G G T T G G A A C C T A G C A T C C T T G C A A C C T T G C T T G G T A C C T A G G T T G C A A C C A T C G A T C G T T G G T A G C T T C C A T G G T A C G T T G C T A C G T T G C T A C G T T G G A T C C A A G C T T C C T T G C A T G G A A G C T A G G A T G G A A C C A A G C T A G G T T C G A T G C T T G C A T C G T T C C T A C C T A G G A A C C T A C G T T G C T T G G A T C C T A G G A A G G T A C G T A C G A A G G T T G C A T G C T A C G A T C G T T G G A T G C T A G G A T C C A T C C T A C G A A C G A T C C A T C C A A G C A A C C T T G G A A C C A A G G T A G C A A C G T T G G A T C G A T G C A T G G A A G G T A C C T A G G T A G C A T C C T A G G T T C C A A G G T A G C A T G G T T G C T T G C T A C G A T G C T T C G A T G C T T C C T T G G A A C G A T G G T A G G T A C G T A G C A A G C T T C G A A G G A A G G T A G C T T G C T T C G A T G C T A G G T A C G T T C G T A C G A A C C T T C C A A C G T T G C A T G C T T C C A T C G A A G G T A G G T A C C A A G C T A C G T A C G A T G C A T G G T A G G T A G C A A C G A T C G T T C G T T C C T A G G A A G C T T G C T A C G A T G G T T G C A A G G T T G C A A G G T A C G T A C C T T G G T A C C A A C G T T C C T T G C T T C G T A C C A A C C T A C G T A G G T A G G T A G C T T C G A T C C A T G G A A G G A A G G A A C C T A G C T T G G T A G C A T C G T T G C A A G G T T G C A A G C T T G C A A G C T A G G A T C G A A G G T A C G T T C C T T C C T A G C T T C C T A G C T T G C T T C G T T G G A A G C A A G G T A C C A A G C T T C C T A G G T T G C A T G C A A G C A T G C A A G G T A C G A T C C T T G C T T G C T A G C A T C C A A C G A T G C A A G G A T C C T A G G A T G C T A G G T T G G T T C C T A C G A T C C A A G G A A G C T T G C T T G G A A G C T T G C T T C C A A G G T A G G T T G G T A C C T T C C T T G G T T G C T T G C T A G C A A C G T A G G T T C C T A G C A A G C T A G G T A G G T A G C A A C G T +A G G T T C G T A C C T A G C A A C C A T G C T A G C T T G G T A G C A A G G T A G G A T G C T T G G A T C G A T G C T A G G T A G C T A C C T T G C T A C C T T G G T T G C A T C C A T G G A A C C T T G C T A C C A T G C T A C C T A G G T A G C A T G C T T C G T T G C A A G C T T C C T A G G T T C C T T C C A T C C T A G C T T C C A A C C T T C G A T G G T A G C T A C C A A G C T T C G T T G C A A G C A A C C A T G G A A G G A A G C T A G C A A G C A A C C A A G C T A G C T T C G A T G C T A C C T T G G A A G G T T C G T A G G A T G G A A C G A A G C T A C C A A C G A A G G T A G G A T G C A A C C T T G C A A C G A T G C T A C G A A C G A A C G A T G C T A C C T A G G T A C G A A G C A T G G A T C G A T C G A T G C A A C C T A G C A A G G A A G G T A G C A A G G T A G G T T C G T A G C T T G C A T G C A A C C A T G G T A C C A A G G A A G C A A G G A A G C A T C G A A C C T A C C A A G G A A C G A A G C A A G G A T C G T A G C A T G C A A C G T T C C A T G C T T G C A T C C T T G G T A G G T A C G T T G G T A C G T A G C T T G C A T G C A T G G A T C G T A G C A T C G T A C C A T G G T A C C T T C G A T G G T T G C T A G G T A G G T T G C T T C C T T C G T T G G T A C C A A G C A T G G A A C C A T G C A A G C T A G C A A G G T T C C T T G C A T C G T T C G A A C G A A G G T A G C T A C G T A G G T T C G A T C C T A G C T A G G A T G C T T C C A T C C T T G C T T C G T A C C A T C C T T C C A A G G T A G G T T G C A A C C A T G C A T G G T T C C A A C C A A G C A A G C T T G C A T G G T T C G T T C C T T C C T T G G A T C G A T G C A T C G A A C G T T C C T T G C T A G C A A C C T A G G T A C G T A G G T A C G T A G C T T G C T A G C A A G C T A C G A A G C A A G C A T G G T T G C A A C G A T G G T A G C T A C G T A C C A T C C T A C G A A G G A A G G A A C C T T G G A T C G A T C C T A C G A T G G T T C G T A C G A A C C T A G G A T G C T T C C A T G C T T C C A T G G T A C G T T G G T A C C A A C C T A C C T T C C T A C C T T C G T A G G A T C G T A C G A T C G A T G G T A C G T A C G A A G C T T G C T T G C A T G G T T G C A T G G T A G G A A G C T A C G T A C C T A C C A T G C A T G C T T C C T T G C A T G G T A C G A A C C T A C C T T G C T A G G T T G G A T C G A A C C T T G C A A G G A A G G A A C C A T G C A A C C T T G C A A G C A T C C A A G G T T G G A A G G T A G G A T C C A T G C T T G C A A G C T A C G A T C C T A C C T A C G T T G C A A C C T A C G T T G C T A G C T A G C T T C C T A G C T A G C T T C C T A G C T A G C A T G C T A G C A T G C A T G C T T G C T T C C A T G G T T G C T T C C T A C C T A C C A A C C A T C C A A G C T A G G T A G C T A C G A T G G T T C C T A C C A A G C A A G G A A G C T T G C T T C C A T C C T T C C T T C C A A G G T A G G T T G C A A C G A A C C T A G C T T G C T T C C A A G G A T C C T A G C A A C G T A G C A T C C A A G C T A C C A A C C A A C G T END GENOTYPES diff --git a/inst/doc/rehh.R b/inst/doc/rehh.R new file mode 100644 index 0000000..20a808c --- /dev/null +++ b/inst/doc/rehh.R @@ -0,0 +1,324 @@ +## ----setup, include=FALSE------------------------------------------------ +knitr::opts_chunk$set(comment=">") + +## ----message=FALSE------------------------------------------------------- +library(rehh) + +## ----results='hide'------------------------------------------------------ +make.example.files() + +## ------------------------------------------------------------------------ +head(read.table("map.inp")) + +## ------------------------------------------------------------------------ +?data2haplohh + +## ------------------------------------------------------------------------ +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE,chr.name=12) + +## ----eval=FALSE---------------------------------------------------------- +# hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", +# recode.allele=TRUE) + +## ----echo=FALSE---------------------------------------------------------- +cat("More than one chromosome name in Map file: map.inp\nWhich chromosome should be considered among:\n1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29\n1:") + +## ----eval=FALSE---------------------------------------------------------- +# 12 + +## ----echo=FALSE---------------------------------------------------------- +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp",recode.allele=TRUE,chr.name=12) + +## ----error=TRUE---------------------------------------------------------- +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE,chr.name=18) + +## ------------------------------------------------------------------------ +hap<-data2haplohh(hap_file="bta12_cgu.thap",map_file="map.inp",haplotype.in.columns=TRUE, + recode.allele=TRUE,chr.name=12) + +## ------------------------------------------------------------------------ +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", + recode.allele=TRUE,popsel=7,chr.name=12) + +## ----eval=FALSE---------------------------------------------------------- +# hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", +# recode.allele=TRUE,chr.name=12) + +## ----echo=FALSE---------------------------------------------------------- +cat("Map file seems OK: 1424 SNPs declared for chromosome 12\nLooks like a FastPHASE haplotype file\nHaplotypes originate from 8 different populations in the fastPhase output file\nChosen pop. is not in the list of pop. number: 1 2 3 4 5 6 7 8\nWhich population should be considered among: 1 2 3 4 5 6 7 8\n1: +") + +## ----eval=FALSE---------------------------------------------------------- +# 7 + +## ----echo=FALSE---------------------------------------------------------- +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp",recode.allele=TRUE,popsel=7,chr.name=12) + +## ----eval=FALSE---------------------------------------------------------- +# ?calc_ehh + +## ---- fig.align='center',fig.keep='all'---------------------------------- +#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details +data(haplohh_cgu_bta12) +#computing EHH statistics for the focal SNP at position 456 +#which display a strong signal of selection +res.ehh<-calc_ehh(haplohh_cgu_bta12,mrk=456) + +## ------------------------------------------------------------------------ +res.ehh$ehh[1:2,454:458] + +## ------------------------------------------------------------------------ +res.ehh$nhaplo_eval[1:2,454:458] + +## ------------------------------------------------------------------------ +res.ehh$freq_all1 + +## ------------------------------------------------------------------------ +res.ehh$ihh + +## ----ehhplot,echo=FALSE,fig.align='center',,out.height="7cm",fig.cap='Graphical output for the \\texttt{calc\\_ehh()} function',fig.pos='!h',fig.lp='fig:'---- +sel_reg <- (colSums(res.ehh$nhaplo_eval) > 0) ; mrk=456 +matplot(haplohh_cgu_bta12@position[sel_reg]/1000000, t(res.ehh$ehh[, sel_reg]),col = c("red", "blue"), lty = 1, type = "l",main = "", bty = "n", xlab = "Position (Mb)",ylab = expression(Extended ~ haplotype ~ homozygosity ~ (italic(EHH)))) +abline(v = haplohh_cgu_bta12@position[mrk]/1000000, lty = 2) +legend("topleft", c("Ancestral Allele", "Derived Allele"),col = c("red", "blue"), bty = "n", lty = 1) + +## ---- eval=FALSE--------------------------------------------------------- +# ?calc_ehhs + +## ------------------------------------------------------------------------ +#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details +data(haplohh_cgu_bta12) +#computing EHH statistics for the focal SNP at position 456 +#which display a strong signal of selection +res.ehhs<-calc_ehhs(haplohh_cgu_bta12,mrk=456) + +## ------------------------------------------------------------------------ +res.ehhs$EHHS_Sabeti_et_al_2007[453:459] + +## ------------------------------------------------------------------------ +res.ehhs$EHHS_Tang_et_al_2007[453:459] + +## ------------------------------------------------------------------------ +res.ehhs$nhaplo_eval[453:459] + +## ------------------------------------------------------------------------ +res.ehhs$IES_Tang_et_al_2007 + +## ------------------------------------------------------------------------ +res.ehhs$IES_Sabeti_et_al_2007 + +## ----ehhsplot,echo=FALSE,fig.align='center',out.height="7cm",fig.cap='Graphical output for the \\texttt{calc\\_ehhs()} function',fig.pos='!h',fig.lp='fig:'---- +sel_reg <- (colSums(res.ehh$nhaplo_eval) > 0) ; mrk=456 +plot(haplohh_cgu_bta12@position[sel_reg]/1000000, res.ehhs$EHHS_Sabeti_et_al_2007[sel_reg],col = "red", lty = 1, type = "l",main = "", bty = "n", xlab = "Position (Mb)",ylab = expression(Site ~ specific ~ italic(EHH) ~ (italic(EHHS)) )) +lines(haplohh_cgu_bta12@position[sel_reg]/1000000, res.ehhs$EHHS_Tang_et_al_2007[sel_reg], col = "blue") +abline(v = haplohh_cgu_bta12@position[mrk]/1000000, lty = 2) +legend("topleft", c("Sabeti et al. (2007)", "Tang et al. (2007)"),col = c("red", "blue"), bty = "n", lty = 1) + +## ----eval=TRUE----------------------------------------------------------- +data(haplohh_cgu_bta12) +res.scan<-scan_hh(haplohh_cgu_bta12) + +## ------------------------------------------------------------------------ +dim(res.scan) + +## ------------------------------------------------------------------------ +head(res.scan) + +## ------------------------------------------------------------------------ +system.time(res.scan<-scan_hh(haplohh_cgu_bta12)) + +## ------------------------------------------------------------------------ +foo<-function(haplo){ +res.ihh=res.ies=matrix(0,haplo@nsnp,2) +for(i in 1:length(haplo@position)){ + res.ihh[i,]=calc_ehh(haplo,mrk=i,plotehh=FALSE)$ihh + tmp=calc_ehhs(haplo,mrk=i,plotehhs=FALSE) + res.ies[i,1]=tmp$IES_Tang_et_al_2007 + res.ies[i,2]=tmp$IES_Sabeti_et_al_2007 +} +list(res.ies=res.ies,res.ihh=res.ihh) +} +system.time(res.scan2<-foo(haplohh_cgu_bta12)) + +## ------------------------------------------------------------------------ +sum(res.scan2$res.ihh[,1]!=res.scan[,4]) + sum(res.scan2$res.ihh[,2]!=res.scan[,5]) + +sum(res.scan2$res.ies[,1]!=res.scan[,6]) + sum(res.scan2$res.ies[,2]!=res.scan[,7]) + +## ----eval=FALSE---------------------------------------------------------- +# for(i in 1:29){ +# hap_file=paste("hap_chr_",i,".pop1",sep="") +# data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) +# res<-scan_hh(data) +# if(i==1){wg.res<-res}else{wg.res<-rbind(wg.res,res)} +# } +# wg.ihs<-ihh2ihs(wg.res) + +## ------------------------------------------------------------------------ +data(wgscan.cgu) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +ihs.cgu<-ihh2ihs(wgscan.cgu) + +## ------------------------------------------------------------------------ +head(ihs.cgu$iHS) + +## ------------------------------------------------------------------------ +head(ihs.cgu$frequency.class) + +## ----eval=FALSE---------------------------------------------------------- +# ihsplot(ihs.cgu,plot.pval=TRUE,ylim.scan=2,main="iHS (CGU cattle breed)") +# + +## ----echo=FALSE,fig.ext="png",fig.align='center',fig.width=16,fig.height=12,fig.cap='Graphical output for the \\texttt{ihsplot()} function'---- +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "iHS (CGU cattle breed)"; cex.main = 1.;cex.axis=0.7 +data = ihs.cgu$iHS +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$iHS, pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(iHS)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) + +## ----eval=FALSE---------------------------------------------------------- +# for(i in 1:29){ +# hap_file=paste("hap_chr_",i,".pop1",sep="") +# data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) +# res<-scan_hh(data) +# if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)} +# hap_file=paste("hap_chr_",i,".pop2",sep="") +# data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) +# res<-scan_hh(data) +# if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)} +# } +# wg.rsb<-ies2rsb(wg.res.pop1,wg.res.pop2) + +## ------------------------------------------------------------------------ +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +cguVSeut.rsb<-ies2rsb(wgscan.cgu,wgscan.eut,"CGU","EUT") + +## ------------------------------------------------------------------------ +head(cguVSeut.rsb) + +## ----eval=FALSE---------------------------------------------------------- +# rsbplot(cguVSeut.rsb,plot.pval=TRUE) + +## ----rsbplot,echo=FALSE,fig.ext="png",fig.align='center',fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the \\texttt{rsbplot()} function',fig.pos='!h'---- +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "Rsb (CGU vs. EUT)"; cex.main = 1.;cex.axis=0.7 +data = cguVSeut.rsb +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data[,3], pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(Rsb)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) + +## ----eval=FALSE---------------------------------------------------------- +# for(i in 1:29){ +# hap_file=paste("hap_chr_",i,".pop1",sep="") +# data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) +# res<-scan_hh(data) +# if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)} +# hap_file=paste("hap_chr_",i,".pop2",sep="") +# data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) +# res<-scan_hh(data) +# if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)} +# } +# wg.xpehh<-ies2xpehh(wg.res.pop1,wg.res.pop2) + +## ------------------------------------------------------------------------ +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +cguVSeut.xpehh<-ies2xpehh(wgscan.cgu,wgscan.eut,"CGU","EUT") + +## ------------------------------------------------------------------------ +head(cguVSeut.xpehh) + +## ----eval=FALSE---------------------------------------------------------- +# xpehhplot(cguVSeut.xpehh,plot.pval=TRUE) + +## ----xpehhplot,echo=FALSE,fig.align='center',fig.ext="png",fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the \\texttt{xpehhplot()} function',fig.pos="!h"---- +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "Rsb (CGU vs. EUT)"; cex.main = 1.;cex.axis=0.7 +data = cguVSeut.xpehh +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data[,3], pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(XPEHH)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) + +## ----comp,echo=TRUE,fig.align='center',fig.ext="png",out.height="7cm",fig.lp='fig:',fig.cap='Comparison of the XPEHH and Rsb estimates across the CGU and EUT populations',fig.pos="!h"---- +plot(cguVSeut.rsb[,3],cguVSeut.xpehh[,3],xlab="Rsb",ylab="XPEHH",pch=16, + cex=0.5,cex.lab=0.75,cex.axis=0.75) +abline(a=0,b=1,lty=2) + +## ----eval=FALSE---------------------------------------------------------- +# distribplot(ihs.cgu$iHS[,3],xlab="iHS") + +## ----distribplot,echo=FALSE,fig.align='center',fig.width=7,out.height="7cm",fig.height=7,fig.lp='fig:',fig.cap='Graphical output for the function \\texttt{distribplot}',fig.pos="!h"---- +layout(matrix(1:2,2,1)) +data=ihs.cgu$iHS[,3] +lty = 1;lwd = 1.5;col = c("blue","red");main = "Genome-wide distribution";xlab = "iHS";cex.main = 1.5;cex.lab = 1.25;qqplot = TRUE +plot(density(data,na.rm = TRUE),main = main,xlab = xlab,col = col[1],lty = lty,lwd = lwd,cex.main = cex.main,cex.lab = cex.lab) + curve(dnorm,col = col[2],add = TRUE) + legend("topright",c("Observed","Gaussian"),bty = "n",col = col,lty = lty,lwd = lwd) + if (qqplot) { + par(mar = c(5,5,4,2) + 0.1) + qqnorm(data[!is.na(data)],cex.main = cex.main,cex.lab = cex.lab,pch = 16,cex = 0.75) + abline(a=0,b=1,lty=2) + } + +## ----bifdia,eval=TRUE,fig.align='center',out.height="12cm",fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the function \\texttt{bifurcation.diagram()}',fig.pos="!h"---- +data(haplohh_cgu_bta12) +layout(matrix(1:2,2,1)) +bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=1,nmrk_l=20,nmrk_r=20, + main="Bifurcation diagram (RXFP2 SNP on BTA12): Ancestral Allele") +bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=2,nmrk_l=20,nmrk_r=20, + main="Bifurcation diagram (RXFP2 SNP on BTA12): Derived Allele") + diff --git a/inst/doc/rehh.Rmd b/inst/doc/rehh.Rmd new file mode 100644 index 0000000..ccc9a25 --- /dev/null +++ b/inst/doc/rehh.Rmd @@ -0,0 +1,632 @@ + %\VignetteEngine{knitr::knitr} + %\VignetteIndexEntry{How to use rehh} + %\usepackage[utf8]{inputenc} +--- +title: "Vignette for the package *rehh* (version 2+)" +author: "Mathieu Gautier, Alexander Klassmann and Renaud Vitalis" +date: "29/07/2016" +output: + pdf_document: + fig_caption: yes + number_sections: yes + toc: yes + html_document: + toc: yes +csl: genetics.csl +bibliography: vignette.bib +--- + +```{r setup, include=FALSE} +knitr::opts_chunk$set(comment=">") +``` + +\newpage +This vignette is aimed at presenting additional information on the R package \emph{rehh} by describing how to use it to perform whole genome scan for footprints of selection using statistics related to the Extended Haplotype Homozygosity (EHH) [@Sabeti2002]. Importantly, the current implementation of tests assumes markers are bi-allelic. + +The \emph{rehh} package is currently available for most platforms (Linux, MS Windows and MacOSX) from the CRAN repository (\url{http://cran.r-project.org/}) and may be installed using standard procedure. Once the package has been successfully installed on your system, it can be loaded using the following command: +```{r message=FALSE} +library(rehh) +``` + +#Input Files +\label{make.example.files} + +The package \emph{rehh} basically requires as input: + +1. haplotype data file(s) (in three possible format) for each population of interest (see \ref{hap.file}) +2. a SNP information file (see \ref{map.file}) + +**Important Note: For a given chromosome, SNPs are assumed to be ordered in the same way in both the haplotype file (columns) and the SNP information file.** + +For illustration purposes, example files that originate from a previously published study on the Creole cattle breed from Guadeloupe (CGU) [@Gautier2011] are provided in the package and can be copied in the working directory with the following command: +```{r results='hide'} +make.example.files() +``` + +In the following examples, the command \texttt{make.example.file()} is assumed to have been run (see above) so that example files are in the working directory. + +##Haplotype data file +\label{hap.file} + +Three haplotype input file formats are supported: + +1. a standard haplotype format. Each line represents a haplotype (the first element being an haplotype identifier) with SNP genotype in columns as in the example file \texttt{bta12\_cgu.hap} created when running the function \texttt{make.example.files()} and that consists of 280 haplotypes (identifier 1 to 280) of 1424 SNPs each. See \ref{LoadDataEx1} for a detailed example. +2. A (transposed) format with haplotype in columns and SNPs in row as in the example file \texttt{bta12\_cgu.thap} created when running the function \texttt{make.example.files()}. Note that this format is similar to the one produced by the phasing program \emph{SHAPEIT2} [@OConnell2014]. See \ref{LoadDataEx2} for a detailed example. +3. the output file format from the phasing program \emph{fastPHASE} [@Scheet2006] as in the \texttt{bta12\_hapguess\_switch.out} example file created when running the function \texttt{make.example.files()}. Note that haplotypes might originate from several different populations (i.e., if the -u \emph{fastPHASE} option was used). See \ref{LoadDataEx3} for a detailed example. + +By default alleles are assumed to be coded as 0 (missing data), 1 (ancestral allele) or 2 (derived allele). Recoding of the alleles in this format, according to the SNP information data file (see \ref{map.file}) can be performed with the \texttt{recode.allele} option of the function \texttt{data2haplohh()} (see \ref{LoadData}). + +##SNP information data file +\label{map.file} + +This data file should contain SNP information as in the \texttt{map.inp} example file created when running the function \texttt{make.example.files()}. Each line contains five columns corresponding to: + +1. the SNP name +2. the SNP chromosome (or scaffold) of origin +3. the SNP position on the chromosome (or scaffold). Note that it is up to the user to choose either physical or genetic map positions (if available). +4. the SNP ancestral allele (as coded in the haplotype input file) +5. the SNP derived alleles (as coded in the haplotype input file) + +The fourth and fifth columns (allele coding) should be filled in but the corresponding information is only used when activating the \texttt{recode.allele} option of the function \texttt{data2haplohh()} (see \ref{LoadData}). In that case, for each SNP, the allele specified in the fourth (respectively fifth) column will be recoded as 1 (respectively 2), any other allele name will be recoded as 0 (i.e., missing data). More importantly, it should be noticed that the ancestral or derived allele information associated to this coding are only relevant for within population tests (based on \emph{iHS}). In other words, if one is only interested in across-population tests (based on \emph{Rsb} or \emph{xpEHH}), assignment of the two SNP alleles in the fourth and fifth column may be performed randomly. + +As an illustration, the following R command displays the first five row of the \texttt{map.inp} example file created when running the function \texttt{make.example.files()}: + +```{r} +head(read.table("map.inp")) +``` + + +##Loading data files +\label{LoadData} +The \texttt{data2haplohh()} function allows to convert data file into an R object of class \texttt{haplohh} subsequently used by the functions of the \emph{rehh} package. The following main options are available to recode alleles or select SNPs (based on Minor Allele Frequency or percentage of missing data) and haplotypes (based on percentage of missing data): + +1. **Allele recoding option**: This option is activated with \texttt{recode.allele=TRUE} and allows to recode haplotype according to the ancestral and derived allele definition available in the SNP information file (fourth and fifth columns) as: 0 (missing data), 1 (ancestral allele) or 2 (derived allele). +2. **Discard haplotypes with a high amount of missing data**. If haplotypes contain missing data (which is generally not the case since most phasing programs allow imputing missing genotypes), it is possible to discard those with less \texttt{min\_perc\_geno.hap} \% of the SNPs genotyped. By default \texttt{min\_perc\_geno.hap=100} meaning that only completely phased haplotypes are retained. +3. **Discard SNPs with a high amount of missing data**. It is possible to discard SNPs genotyped on less than \texttt{min\_perc\_geno.snp} \% of the haplotypes. By default \texttt{min\_perc\_geno.snp=100} meaning that only fully genotyped SNPs are retained. +4. **Discard SNPs with a low Minor Allele Frequency**. It is possible to discard SNPs with a MAF below \texttt{min\_maf}. This is generally not recommended and by default \texttt{min\_maf=0} meaning that all SNPs are retained.\footnote{The arguments \texttt{min\_perc\_geno.hap}, \texttt{min\_perc\_geno.snp} and \texttt{min\_maf} are evaluated in this order.} + +More details about the different arguments of the function are available in the documentation accessible using the command: +```{r} +?data2haplohh +``` + +In the following we detail three different examples based on the example data files provided with the package (see \ref{make.example.files}). + +###Example 1: reading haplotype file in standard format +\label{LoadDataEx1} +In this example, the example haplotype input file \texttt{bta12\_cgu.hap} (standard format) and SNP information input files \texttt{map.inp} are converted into an \texttt{haplohh} object named \texttt{hap}. Because the map file contains information for SNPs mapping to other chromosomes than the one of interest (BTA12), we use the option \texttt{chr.name=12}. Allele recoding is activated (\texttt{recode.allele=TRUE}) to allow recoding alleles in the \emph{rehh} format (0,1 or 2). +```{r } +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE,chr.name=12) +``` + +If no value is specified for \texttt{chr.name} argument and more than one chromosome is detected in the map file, the function asks interactively which chromosome to choose: + +```{r eval=FALSE} +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE) +``` +```{r echo=FALSE} +cat("More than one chromosome name in Map file: map.inp\nWhich chromosome should be considered among:\n1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29\n1:") +``` +```{r eval=FALSE} +12 +``` +```{r echo=FALSE} +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp",recode.allele=TRUE,chr.name=12) +``` + +Finally, as an example of error message, the following message is prompted if the number of SNPs in the chromosome (for instance when a wrong chromosome is declared) does not correspond to the one in the haplotype file: + +```{r error=TRUE} +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE,chr.name=18) +``` + +###Example 2: reading haplotype file in transposed format (\emph{SHAPIT2}--like) +\label{LoadDataEx2} + +In this example, the example haplotype input file \texttt{bta12\_cgu.thap} (transposed format) and SNP information input files \texttt{map.inp} are converted into an \texttt{haplohh} object named \texttt{hap}. Setting \texttt{haplotype.in.columns=TRUE} informs the function that the haplotype file is in transposed format: +```{r} +hap<-data2haplohh(hap_file="bta12_cgu.thap",map_file="map.inp",haplotype.in.columns=TRUE, + recode.allele=TRUE,chr.name=12) +``` + +###Example 3: reading haplotype file in \emph{fastPHASE} output format +\label{LoadDataEx3} +In this example, the example \emph{fastPHASE} output file \texttt{bta12\_hapguess\_switch.out} and SNP information input files \texttt{map.inp} are +converted into a \texttt{haplohh} object named \texttt{haplo}. As explained above we use the option \texttt{chr.name=12}. +Because, haplotypes originate from several populations (the -u \emph{fastPHASE} option was used), we specify the population of interest +(in our example the 280 haplotypes from the CGU population, see above) using the option \texttt{popsel=7} +(7 corresponding to the code of CGU in the example \emph{fastPHASE} input files). + +```{r} +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", + recode.allele=TRUE,popsel=7,chr.name=12) +``` + +If no value is specified for the \texttt{popsel} argument and more than one population is detected in the \emph{fastPHASE} output file, the function asks interactively which population to chose: + +```{r eval=FALSE} +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", + recode.allele=TRUE,chr.name=12) +``` +```{r echo=FALSE} +cat("Map file seems OK: 1424 SNPs declared for chromosome 12\nLooks like a FastPHASE haplotype file\nHaplotypes originate from 8 different populations in the fastPhase output file\nChosen pop. is not in the list of pop. number: 1 2 3 4 5 6 7 8\nWhich population should be considered among: 1 2 3 4 5 6 7 8\n1: +") +``` +```{r eval=FALSE} +7 +``` +```{r echo=FALSE} +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp",recode.allele=TRUE,popsel=7,chr.name=12) +``` + +#Computing \emph{EHH}-based statistics for individual markers with the \texttt{calc\_ehh()}, \texttt{calc\_ehhs()} and \texttt{scan\_hh()} functions +##Definition and Computation + +###The (allele-specific) Extended Haplotype Homozygosity (\emph{EHH}) +\label{EHH} +For a given core allele (i.e., the ancestral or derived allele) at a focal SNP, the (allele--specific) extended haplotype homozygosity (\emph{EHH}) is defined as the probability that two randomly chosen chromosomes (carrying the core allele considered) are identical by descent (as assayed by homozygosity at all SNPs) over a given surrounding chromosome region [@Sabeti2002]. The \emph{EHH} thus aims at measuring to which extent an extended haplotype is transmitted without recombination. In practice, the \emph{EHH} ($\mathrm{EHH}_{s,t}$) of a tested core allele $a_s$ ($a_s=1$ or $a_s=2$) for a focal SNP $s$ over the chromosome interval extending to SNP $t$ is computed as: +\begin{equation} +\label{ehh.def} +\mathrm{EHH}_{s,t}=\frac{1}{n_{a_s}(n_{a_s}-1)}\sum\limits_{k=1}^{K_{a_s,t}}n_k(n_k-1) +\end{equation} +where $n_{a_s}$ represents the number of haplotype carrying the core allele $a_s$, $K_{a_s,t}$ represents the number of different extended haplotypes (from SNP $s$ to SNP $t$) carrying $a_s$ and $n_k$ is the number of the extended haplotype $k$ (i.e., $n_{a_s}=\sum\limits_{k=1}^{K_{a_s,t}}n_k$). + +###The integrated (allele-specific) \emph{EHH} (\emph{iHH}) +\label{iHH} +By definition, irrespective of the allele considered, \emph{EHH} starts at 1, and decays monotonically to 0 with increasing distance from the focal SNP. For a given core allele, the integrated \emph{EHH} (\emph{iHH}) is defined as the area under the \emph{EHH} curve with respect to map position [@Voight2006]\footnote{In their seminal paper, Voight et al. considered genetic distances and apply a penalty (proportional to physical distances) for successive SNPs separated by more than 20 kb. In addition, they did not compute \emph{iHH} if any physical distance between a pair of neighboring SNPs was above 200 kb. We did not implement such an approach in \emph{rehh} although this might easily be done (providing relevant information is available for the genome of interest) by modifying the positions of the markers in SNP information input file.}. In \emph{rehh}, \emph{iHH} is computed using the trapezoid method. In practice, the integral might only be computed for the regions of the curve above an arbitrarily small \emph{EHH} value (e.g., \emph{EHH}>0.05). + +###The site-specific Extended Haplotype Homozygosity (\emph{EHHS}) +\label{EHHS} +For a given core SNP, the (site--specific) extended haplotype homozygosity (\emph{EHHS}) is defined as the probability that two randomly chosen chromosomes are identical by descent (as assayed by homozygosity at all SNPs) over a given surrounding chromosome region. \emph{EHHS} might roughly be viewed as linear combination of the \emph{EHH}'s for the two alternative alleles with weights function of the corresponding allele frequencies. Two different \emph{EHHS} estimators further denoted as $\mathrm{EHHS}^{\text{Sab}}$ [@Sabeti2007] and $\mathrm{EHHS}^{\text{Tang}}$ [@Tang2007] have been proposed. For a focal SNP $s$ over a chromosome interval extending to SNP $t$, these are computed as (following the same notation as above): +\begin{equation} +\label{ehhssab.def} +\mathrm{EHHS}^{\text{Sab}}_{s,t}=\frac{1}{n_s(n_s-1)}\sum\limits_{a_s=1}^{a_s=2}\left(\sum\limits_{k=1}^{K_{a_s,t}}n_k(n_k-1)\right) +\end{equation} +where $n_s=\sum\limits_{a_s=1}^{a_s=2}n_{a_s}$ and +\begin{equation} +\label{ehhstang.def} +\mathrm{EHHS}^{\text{Tang}}_{s,t}=\frac{1-h_{hap}^{(s,t)}}{1-h_{all}^{(s)}} +\end{equation} +where: + +1. $h_{all}^{(s)}=\frac{n_s}{n_s-1}\left(1-\frac{1}{n_s^2}\sum\limits_{a_s=1}^{a_s=2}n_{a_s}^2 \right )$ is an estimator of the focal SNP heterozygosity +2. $h_{hap}^{(s,t)}=\frac{n_s}{n_s-1}\left(1-\frac{1}{n_s^2}\sum\limits_{a_s=1}^{a_s=2}\left(\sum\limits_{k=1}^{K_{a_s,t}}n_k^2 \right )\right)$ is an estimator of haplotype heterozygosity across the chromosome region extending from SNP $s$ to SNP $t$. + +###The integrated \emph{EHHS} (\emph{iES}) +\label{iES} +As for the \emph{EHH} (see \ref{iHH}), \emph{EHHS} starts at 1 and decays monotonically to 0 with increasing distance from the focal SNP. For a given focal SNP, and in a similar fashion as the \emph{iHH}, \emph{iES} is defined as the integrated \emph{EHHS} [@Tang2007]. Depending on the \emph{EHHS} estimator considered (respectively, $\mathrm{EHHS}^{\text{Sab}}$ and $\mathrm{EHHS}^{\text{Tang}}$), two different \emph{iES} estimators, that we further denoted as $\mathrm{iES}^{\text{Sab}}$ and $\mathrm{iES}^{\text{Tang}}$ respectively, can be computed. As for \emph{iHH}, the \emph{iES} integral is computed using the trapezoid method and might only be computed for the regions of the curve above an arbitrarily small \emph{EHHS} value (e.g., \emph{EHHS}>0.05). + +###Dealing with missing data + +In the computation of both \emph{EHH} and \emph{EHHS} from a focal SNP $s$ to a SNP $t$, only extended haplotypes with no missing data are considered. As a consequence, the number of extended haplotypes retained to compute these two statistics might decrease with distance from the focal SNP. However if the number of available extended haplotypes falls below a threshold (e.g., \texttt{limhaplo}=5), \emph{EHH} and \emph{EHHS} are not computed further. Note however that most phasing programs (such as \emph{fastPHASE} or \emph{SHAPEIT2}) allow to impute missing genotypes resulting in phased haplotypes with no missing data. + +##The function \texttt{calc\_ehh()} +\label{calcehh} +The \texttt{calc\_ehh()} function allows to compute \emph{EHH} for both the ancestral ($a_s=1$) and derived ($a_s=2$) alleles at the $s^\text{th}$ SNP relative to each SNP ($t$) upstream and downstream and corresponding \emph{iHH}. The two options \texttt{limehh} and \texttt{limhaplo} allow to specify condition to stop computing \emph{EHH} (see \ref{EHH}). By default \texttt{limehh}=0.05 and \texttt{limhaplo}=2. Finally, if \texttt{plotehh=TRUE}, the decay of \emph{EHH} for both the ancestral and derived alleles is plotted against SNP map position (\texttt{main\_leg} allows to change the plot legend). More details are available in the R documentation by using the command: +```{r eval=FALSE} +?calc_ehh +``` +In the following example,the \emph{EHH} statistics are computed for both the ancestral and derived allele of the $456^{\text{th}}$ focal SNP. Note that the \texttt{haplohh\_cgu\_bta12} object was generated using the \texttt{data2haplohh()} function with the example input files (\ref{LoadDataEx1}). For convenience, it is stored as an example object (accessible with the R function \texttt{data}) as shown below: +```{r, fig.align='center',fig.keep='all'} +#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details +data(haplohh_cgu_bta12) +#computing EHH statistics for the focal SNP at position 456 +#which display a strong signal of selection +res.ehh<-calc_ehh(haplohh_cgu_bta12,mrk=456) +``` +The five different elements of the resulting \texttt{res.ehh} object are as follows: +```{r} +res.ehh$ehh[1:2,454:458] +``` +```{r} +res.ehh$nhaplo_eval[1:2,454:458] +``` +```{r} +res.ehh$freq_all1 +``` +```{r} +res.ehh$ihh +``` +In addition, as \texttt{plotehh=TRUE} by default, we obtain the following plot (Figure \ref{fig:ehhplot}): +```{r ehhplot,echo=FALSE,fig.align='center',,out.height="7cm",fig.cap='Graphical output for the \\texttt{calc\\_ehh()} function',fig.pos='!h',fig.lp='fig:'} +sel_reg <- (colSums(res.ehh$nhaplo_eval) > 0) ; mrk=456 +matplot(haplohh_cgu_bta12@position[sel_reg]/1000000, t(res.ehh$ehh[, sel_reg]),col = c("red", "blue"), lty = 1, type = "l",main = "", bty = "n", xlab = "Position (Mb)",ylab = expression(Extended ~ haplotype ~ homozygosity ~ (italic(EHH)))) +abline(v = haplohh_cgu_bta12@position[mrk]/1000000, lty = 2) +legend("topleft", c("Ancestral Allele", "Derived Allele"),col = c("red", "blue"), bty = "n", lty = 1) +``` + +##The function \texttt{calc\_ehhs()} + +The \texttt{calc\_ehhs()} function allows to compute the \emph{EHHS} (both the $\mathrm{EHHS}^{\text{Sab}}$ and $\mathrm{EHHS}^{\text{Tang}}$ estimators) at the $s^\text{th}$ SNP relative to each SNP ($t$) upstream and downstream. This function also compute the corresponding \emph{iES} ($\mathrm{iES}^{\text{Sab}}$ and $\mathrm{iES}^{\text{Tang}}$ estimators respectively). The two options \texttt{limehhs} and \texttt{limhaplo} allow to specify condition to stop computing \emph{EHHS} (see \ref{EHHS}). By default \texttt{limehhs}=0.05 and \texttt{limhaplo}=2. Finally, if \texttt{plotehhs=TRUE}, the decay of \emph{EHHS} is plotted against SNP map position (\texttt{main\_leg} allows to change the plot legend). More details are available in the R documentation by using the command: +```{r, eval=FALSE} +?calc_ehhs +``` +In the following example, the \emph{EHHS} statistics are computed for the $456^{\text{th}}$ focal SNP on the \texttt{haplohh\_cgu\_bta12} object defined above (see \ref{calcehh}) was generated using the \texttt{data2haplohh()} function with the example input files (see \ref{LoadDataEx1}) described above. For convenience, it is stored as an example object (accessible with the R function \texttt{data}). + +```{r} +#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details +data(haplohh_cgu_bta12) +#computing EHH statistics for the focal SNP at position 456 +#which display a strong signal of selection +res.ehhs<-calc_ehhs(haplohh_cgu_bta12,mrk=456) +``` +The five different elements of the resulting \texttt{res.ehhs} object are as follows: +```{r} +res.ehhs$EHHS_Sabeti_et_al_2007[453:459] +``` +```{r} +res.ehhs$EHHS_Tang_et_al_2007[453:459] +``` +```{r} +res.ehhs$nhaplo_eval[453:459] +``` +```{r} +res.ehhs$IES_Tang_et_al_2007 +``` +```{r} +res.ehhs$IES_Sabeti_et_al_2007 +``` +In addition, as \texttt{plotehh=TRUE} by default, we obtain the following plot (Figure \ref{fig:ehhsplot}): +```{r ehhsplot,echo=FALSE,fig.align='center',out.height="7cm",fig.cap='Graphical output for the \\texttt{calc\\_ehhs()} function',fig.pos='!h',fig.lp='fig:'} +sel_reg <- (colSums(res.ehh$nhaplo_eval) > 0) ; mrk=456 +plot(haplohh_cgu_bta12@position[sel_reg]/1000000, res.ehhs$EHHS_Sabeti_et_al_2007[sel_reg],col = "red", lty = 1, type = "l",main = "", bty = "n", xlab = "Position (Mb)",ylab = expression(Site ~ specific ~ italic(EHH) ~ (italic(EHHS)) )) +lines(haplohh_cgu_bta12@position[sel_reg]/1000000, res.ehhs$EHHS_Tang_et_al_2007[sel_reg], col = "blue") +abline(v = haplohh_cgu_bta12@position[mrk]/1000000, lty = 2) +legend("topleft", c("Sabeti et al. (2007)", "Tang et al. (2007)"),col = c("red", "blue"), bty = "n", lty = 1) +``` + +##The function \texttt{scan\_hh()} +\label{fun.scanhh} +The \texttt{scan\_hh()} function allows to efficiently compute \emph{IHH} (for both the ancestral and derived alleles) and \emph{IES} (both the $\mathrm{iES}^{\text{Sab}}$ and $\mathrm{iES}^{\text{Tang}}$ estimators) for all the SNPs in the \texttt{haplohh} object considered. The options \texttt{limehh}, \texttt{limehhs} and \texttt{limhaplo} specify conditions to stop computing \emph{EHH} and \emph{EHHS}. By default \texttt{limehh}=\texttt{limehhs}=0.05 and \texttt{limhaplo}=2. Finally, the option \texttt{threads}, set by dafault to \texttt{threads}=1, allows to specify the number of available threads to parallelize computation (parallelization being carried out over SNPs). +For instance to scan the \texttt{haplohh\_cgu\_bta12} object (containing data on 1424 SNPs for 280 haplotypes), one may use the following command: +```{r,eval=TRUE} +data(haplohh_cgu_bta12) +res.scan<-scan_hh(haplohh_cgu_bta12) +``` +The resulting object \texttt{res.scan} is a data frame with \texttt{haplohh\_cgu\_bta12\@nsnp} (number of SNPs declared in the \texttt{haplohh} object) and seven columns giving for each SNP: + +1. The SNP chromosome of origin +2. The SNP position +3. The SNP ancestral allele frequency +4. The estimated \emph{IHH} for the ancestral allele (\emph{IHH\_A}) +5. The estimated \emph{IHH} for the derived allele (\emph{IHH\_D}) +6. The estimated $\mathrm{iES}^{\text{Tang}}$ +7. The estimated $\mathrm{iES}^{\text{Sab}}$. + +As an example, the following R codes provide the dimension and the first five rows of the \texttt{res.scan} data frame obtained above: +```{r} +dim(res.scan) +``` +```{r} +head(res.scan) +``` +Note that running \texttt{scan\_hh()} is more efficient than running \texttt{calc\_ehh()} and \texttt{calc\_ehhs()} in turn as shown in the example below (\texttt{scan\_hh()}:. +```{r} +system.time(res.scan<-scan_hh(haplohh_cgu_bta12)) +``` +```{r} +foo<-function(haplo){ +res.ihh=res.ies=matrix(0,haplo@nsnp,2) +for(i in 1:length(haplo@position)){ + res.ihh[i,]=calc_ehh(haplo,mrk=i,plotehh=FALSE)$ihh + tmp=calc_ehhs(haplo,mrk=i,plotehhs=FALSE) + res.ies[i,1]=tmp$IES_Tang_et_al_2007 + res.ies[i,2]=tmp$IES_Sabeti_et_al_2007 +} +list(res.ies=res.ies,res.ihh=res.ihh) +} +system.time(res.scan2<-foo(haplohh_cgu_bta12)) +``` +Note however that the same results are obtained (since the same options were used) as illustrated by the following R code: +```{r} +sum(res.scan2$res.ihh[,1]!=res.scan[,4]) + sum(res.scan2$res.ihh[,2]!=res.scan[,5]) + +sum(res.scan2$res.ies[,1]!=res.scan[,6]) + sum(res.scan2$res.ies[,2]!=res.scan[,7]) +``` +#Computing \emph{iHS}, \emph{Rsb} and \emph{xpEHH}: the \texttt{ihh2ihs()},\texttt{ies2rsb()} and \texttt{ies2xpehh()} functions + +##Within population test: the \emph{iHS} +###Definition +\label{def.ihs} +Let $\mathrm{UniHS}$ represent the log-ratio of the \emph{iHH} for its ancestral (\emph{iHH}$_a$) and derived (\emph{iHH}$_d$) alleles: +$$\mathrm{UniHS}=\log\left(\frac{\mathrm{iHH}_a}{\mathrm{iHH}_d}\right)$$ +The \emph{iHS} of a given focal SNP $s$ ($\mathrm{iHS}(s)$) is then defined as its standardized $\mathrm{UniHS}$ ($\mathrm{UniHS}(s)$) following [@Voight2006]: +$$\mathrm{iHS}(s)=\frac{\mathrm{UniHS}(s) - \mu^{p_s}_\mathrm{UniHS}}{\sigma^{p_s}_\mathrm{UniHS}}$$ +where $\mu^{p_s}_\mathrm{UniHS}$ and $\sigma^{p_s}_\mathrm{UniHS}$ represent the average and standard deviation of the $\mathrm{UniHS}$ computed over all the SNPs with a derived allele frequency $p_s$ similar to that of the core SNP $s$. In practice, the derived allele frequencies are generally binned so that each bin are large enough (e.g., >10 SNPs) to obtain reliable estimate of $\mu^{p_s}_\mathrm{UniHS}$ and $\sigma^{p_s}_\mathrm{UniHS}$. + +Note that the \emph{iHS} is constructed to have an approximately standard Gaussian distribution and to be comparable across SNPs regardless of their underlying allele frequencies. Hence, one may further transform \emph{iHS} into $p_\mathrm{iHS}$ [@Gautier2011]: +$$p_\mathrm{iHS}=-\log_{10}\left(1-2|\Phi\left(\mathrm{iHS}\right)-0.5|\right)$$ +where $\Phi\left(x\right)$ represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical \emph{iHS} distribution is a fair approximation of the neutral distribution), $p_\mathrm{iHS}$ might thus be interpreted as a two-sided P-value (on a $-\log_{10}$ scale) associated to the neutral hypothesis of no selection. + +###The function \texttt{ihh2ihs()} +\label{cgu.ihs} +The \texttt{ihh2ihs()} function allows to compute \emph{iHS} using a matrix of \emph{iHH} statistics (for both the ancestral and derived alleles) in the same format as obtained from the \texttt{scan\_hh()} function (see \ref{fun.scanhh}). The argument \texttt{minmaf} allows to remove SNPs according to their MAF (by default SNPs with a MAF<\texttt{minmaf}=0.05 are discarded from the standardization). The argument \texttt{freqbin} controls the size of the allele frequency bins used to perform standardization (see \ref{def.ihs}). More precisely allele frequency bins vary from \texttt{minmaf} to 1-\texttt{minmaf} per step of size \texttt{freqbin} (by default \texttt{freqbin}=0.025). Note that if \texttt{freqbin} is set to 0 (e.g., with a large number of SNPs and few haplotypes), standardization is performed considering each observed frequency as a frequency class. + +For instance, to perform a whole genome scan one might run \texttt{scan\_hh()} in turn on haplotype data from each chromosome and concatenate the resulting matrices before standardization. In the following example, we assume that the haplotype files are named as \texttt{hap\_chr\_i.pop1} where the chromosome number $i$ goes from 1 to 29 and the SNP information file is named \texttt{snp.info}. The R code below then generates a matrix \texttt{wg.res} with \emph{iHH$_a$} and \emph{iHH$_d$} estimates for all SNPs in an appropriate format to perform standardization with the \texttt{ihh2ihs} function: +```{r,eval=FALSE} +for(i in 1:29){ + hap_file=paste("hap_chr_",i,".pop1",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res<-res}else{wg.res<-rbind(wg.res,res)} + } +wg.ihs<-ihh2ihs(wg.res) +``` +As a matter of illustration, results of a similar genome scan [@Gautier2011] are provided as example data sets. The following R code allows to compute the \emph{iHS} for the CGU population: +```{r} +data(wgscan.cgu) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +ihs.cgu<-ihh2ihs(wgscan.cgu) +``` +The corresponding object \texttt{ihs.cgu} is a list with two elements corresponding to + +1. a matrix of SNP \emph{iHS} and the corresponding $p_\mathrm{iHS}$ (P-values in a $-\log_10$ scale assuming the \emph{iHS} are normally distributed under the neutral hypothesis). For instance, the five first rows of the \texttt{ihs.cgu\$iHS} data frame are displayed below using the following R command: +```{r} +head(ihs.cgu$iHS) +``` +2.a matrix summarizing the allele frequency bins. For instance, the five first rows of the \texttt{ihs.cgu\$frequency.class} data frame are displayed below using the following R command: +```{r} +head(ihs.cgu$frequency.class) +``` + +###Manhattan plot of the results: the function \texttt{ihsplot()} + +The \texttt{ihsplot()} function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the list object produced by the function \texttt{ihh2ies()}. Various options are available to modify the graphical display (see \texttt{?ihsplot}). +```{r,eval=FALSE} +ihsplot(ihs.cgu,plot.pval=TRUE,ylim.scan=2,main="iHS (CGU cattle breed)") + +``` + +```{r ,echo=FALSE,fig.ext="png",fig.align='center',fig.width=16,fig.height=12,fig.cap='Graphical output for the \\texttt{ihsplot()} function'} +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "iHS (CGU cattle breed)"; cex.main = 1.;cex.axis=0.7 +data = ihs.cgu$iHS +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$iHS, pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(iHS)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +``` + +##The \emph{Rsb}--based pairwise population test +###Definition +For a given SNP $s$, let $$\mathrm{LRiES}(s)^{\text{Tang}}=\log\left(\frac{\mathrm{iES}_\text{pop1}(s)^{\text{Tang}}}{\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}}\right)$$ represent the log-ratio of the $\mathrm{iES}_\text{pop1}(s)^{\text{Tang}}$ and $\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}$ computed in the pop1 and pop2 populations (see \ref{iES}). + +The \emph{Rsb} for a given focal SNP is then defined as the standardized $\mathrm{LRiES}(s)^{\text{Tang}}$ [@Tang2007]: + +\begin{equation} +\mathrm{rSB}(s)=\frac{\mathrm{LRiES}(s)^{\text{Tang}} - \text{med}_{\mathrm{LRiES}^{\text{Tang}}}}{\sigma_{\mathrm{LRiES}^{\text{Tang}}}} +\end{equation} +where $\text{med}_{\mathrm{LRiES}^{\text{Tang}}}$ and $\sigma_{\mathrm{LRiES}^{\text{Tang}}}$ represent the median and standard deviation of the $\mathrm{LRiES}(s)^{\text{Tang}}$ computed over all the analyzed SNPs. Note that the median is used instead of the mean because it is less sensitive to extreme data points [@Tang2007]. +More importantly, it should be noticed that the information about the ancestral and derived status of alleles at the focal SNP is not needed. + +As for the \emph{iHS} (see \ref{def.ihs}), \emph{Rsb} is constructed to have an approximately standard Gaussian distribution and may further be transformed into $p_\mathrm{rSB}$: +\begin{equation} +p_\mathrm{rSB}=-\log_{10}\left(1-2|\Phi\left(\mathrm{rSB}\right)-0.5|\right) +\end{equation} +where $\Phi\left(x\right)$ represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical \emph{Rsb} distribution is a fair approximation of their corresponding neutral distributions), $p_\mathrm{rSB}$ might thus be interpreted as a two-sided P-value (in a $-\log_{10}$ scale) associated to the neutral hypothesis of no selection. +Alternatively, $p_\mathrm{rSB}$ might also be computed [@Gautier2011]: +\begin{equation} +p\prime_\mathrm{rSB}=-\log_{10}\left(|\Phi\left(\mathrm{rSB}\right)|\right) +\end{equation} +$p\prime_\mathrm{rSB}$ and $p\prime_\mathrm{rSB}$ might then be interpreted as a one-sided P-value (in a $-\log_{10}$ scale) allowing the identification of those sites displaying a significantly high extended haplotype homozygosity in population $pop2$ (represented in the denominator of the corresponding $\mathrm{LRiES}$) relatively to the $pop1$ reference population. + +###The function \texttt{ies2rsb()} +\label{res.rsb} + +The \texttt{ies2rsb()} function allows to compute \emph{Rsb} using two data frames containing the \emph{iES} statistics for each of the two populations considered in the same format as the one obtained after running the \texttt{scan\_hh()} function (see \ref{fun.scanhh}). +For instance, to perform a genome scan one might first run for each population \texttt{scan\_hh()} in turn on haplotype data from each chromosome and concatenate the resulting matrices. In the following example, we assume that the haplotype files are named as \texttt{hap\_chr\_i.pop1} and \texttt{hap\_chr\_i.pop2} where $i$ is the chromosome number (going from 1 to 29), the suffixes pop1 and pop2 indicate the population of origin and the SNP information file is named \texttt{snp.info}. The R code below then generates two data frames (\texttt{wg.res.pop1} and \texttt{wg.res.pop2}) containing the results from all SNPs in the appropriate format to compute \emph{Rsb} with the \texttt{ies2rsb()} function: + +```{r,eval=FALSE} +for(i in 1:29){ + hap_file=paste("hap_chr_",i,".pop1",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)} + hap_file=paste("hap_chr_",i,".pop2",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)} + } +wg.rsb<-ies2rsb(wg.res.pop1,wg.res.pop2) +``` +As a matter of illustration, one may consider results from a similar genome scan [@Gautier2011] provided as example data sets and compute for each SNP the \emph{Rsb} between the CGU and EUT populations as follows: +```{r} +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +cguVSeut.rsb<-ies2rsb(wgscan.cgu,wgscan.eut,"CGU","EUT") +``` + +The resulting object \texttt{cguVSeut.rsb} is a data frame with of SNP \emph{Rsb} (and corresponding P-Values assuming \emph{Rsb} are normally distributed under the neutral hypothesis). Note that either bilateral (default) or unilateral might be performed (\texttt{method} argument). The five first rows of the \texttt{cguVSeut.rsb} data frame are displayed below using the following R command: + +```{r} +head(cguVSeut.rsb) +``` +###Manhattan plot of the results: the function \texttt{rsbplot()} + +The \texttt{rsbplot()} function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the data frame produced by the function \texttt{ies2rsb()}. Various options are available to modify the graphical display (see \texttt{?rsbplot}). As an example, the Figure \ref{fig:rsbplot} below provides the output of the function \texttt{rsbplot} for the \emph{xpEHH} computed above across the CGU and EUT populations (see \ref{res.rsb}). Figure \ref{fig:rsbplot} was drawn using the following R code: +```{r,eval=FALSE} +rsbplot(cguVSeut.rsb,plot.pval=TRUE) +``` + +```{r rsbplot,echo=FALSE,fig.ext="png",fig.align='center',fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the \\texttt{rsbplot()} function',fig.pos='!h'} +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "Rsb (CGU vs. EUT)"; cex.main = 1.;cex.axis=0.7 +data = cguVSeut.rsb +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data[,3], pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(Rsb)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +``` + +##The \emph{xpEHH}--based pairwise population test +###Definition +The \emph{xpEHH} statistics [@Sabeti2007] is similar to the \emph{Rsb} except that it is based on the $\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}$ (instead of $\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}$) estimator of the \emph{iES} (see \ref{iES}). Hence, for or a given SNP $s$, let $$\mathrm{LRiES}(s)^{\text{Sab}}=\log\left(\frac{\mathrm{iES}_\text{pop1}(s)^{\text{Sab}}}{\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}}\right)$$ represent the log-ratio of the $\mathrm{iES}_\text{pop1}(s)^{\text{Sab}}$ and $\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}$ computed in the pop1 and pop2 populations (see \ref{iES}). + +The \emph{xpEHH} for a given focal SNP is then defined as the standardized $\mathrm{LRiES}(s)^{\text{Sab}}$ [@Sabeti2007]: + +\begin{equation} +\mathrm{rSB}(s)=\frac{\mathrm{LRiES}(s)^{\text{Sab}} - \text{med}_{\mathrm{LRiES}^{\text{Sab}}}}{\sigma_{\mathrm{LRiES}^{\text{Sab}}}} +\end{equation} +where $\text{med}_{\mathrm{LRiES}^{\text{Sab}}}$ and $\sigma_{\mathrm{LRiES}^{\text{Sab}}}$ represent the median and standard deviation of the $\mathrm{LRiES}(s)^{\text{Sab}}$ computed over all the analyzed SNPs. +More importantly, it should be noticed that the information about the ancestral and derived status of alleles at the focal SNP is not needed. + +As for the \emph{iHS} (see \ref{def.ihs}) and \emph{Rsb}, \emph{xpEHH} is constructed to have an approximately standard Gaussian distribution and may further be transformed into $p_\mathrm{xpEHH}$: +\begin{equation} +p_\mathrm{xpEHH}=-\log_{10}\left(1-2|\Phi\left(\mathrm{xpEHH}\right)-0.5|\right) +\end{equation} +where $\Phi\left(x\right)$ represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical \emph{xpEHH} distribution is a fair approximation of their corresponding neutral distributions), $p_\mathrm{xpEHH}$ might thus be interpreted as a two-sided P-value (in a $-\log_{10}$ scale) associated to the neutral hypothesis of no selection. +Alternatively, $p_\mathrm{xpEHH}$ might also be computed [@Gautier2011]: +\begin{equation} +p\prime_\mathrm{xpEHH}=-\log_{10}\left(|\Phi\left(\mathrm{xpEHH}\right)|\right) +\end{equation} +$p\prime_\mathrm{xpEHH}$ and $p\prime_\mathrm{xpEHH}$ might then be interpreted as a one-sided P-value (in a $-\log_{10}$ scale) allowing the identification of those sites displaying a significantly high extended haplotype homozygosity in population $pop2$ (represented in the denominator of the corresponding $\mathrm{LRiES}$) relatively to the $pop1$ reference population. + +###The function \texttt{ies2xpehh()} +\label{res.xpehh} + +The \texttt{ies2xpehh()} function allows to compute \emph{xpEHH} using two data frames containing the \emph{iES} statistics for each of the two populations considered in the same format as the one obtained after running the \texttt{scan\_hh()} function (see \ref{fun.scanhh}). +For instance, to perform a genome scan one might first run for each population \texttt{scan\_hh()} in turn on haplotype data from each chromosome and concatenate the resulting matrices. In the following example, we assume that the haplotype files are named as \texttt{hap\_chr\_i.pop1} and \texttt{hap\_chr\_i.pop2} where $i$ is the chromosome number (going from 1 to 29), the suffixes pop1 and pop2 indicate the population of origin and the SNP information file is named \texttt{snp.info}. The R code below then generates two data frames (\texttt{wg.res.pop1} and \texttt{wg.res.pop2}) containing the results from all SNPs in the appropriate format to compute \emph{Rsb} with the \texttt{ies2rsb()} function: + +```{r,eval=FALSE} +for(i in 1:29){ + hap_file=paste("hap_chr_",i,".pop1",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)} + hap_file=paste("hap_chr_",i,".pop2",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)} + } +wg.xpehh<-ies2xpehh(wg.res.pop1,wg.res.pop2) +``` +As a matter of illustration, one may consider results from a similar genome scan [@Gautier2011] provided as example data sets and compute for each SNP the \emph{xpEHH} between the CGU and EUT populations as follows: +```{r} +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +cguVSeut.xpehh<-ies2xpehh(wgscan.cgu,wgscan.eut,"CGU","EUT") +``` + +The resulting object \texttt{cguVSeut.xpehh} is a data frame with of SNP \emph{xpEHH} (and corresponding P-values assuming \emph{xpEHH} are normally distributed under the neutral hypothesis). Note that either bilateral (default) or unilateral might be performed (\texttt{method} argument). The five first rows of this data frame are displayed below using the following R command: + +```{r} +head(cguVSeut.xpehh) +``` +###Manhattan plot of the results: the function \texttt{xpehhplot()} + +The \texttt{xpehhplot()} function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the data frame produced by the function \texttt{ies2xpehh()}. Various options are available to modify the graphical display (see \texttt{?xpehhplot}). +As an example, the Figure \ref{fig:xpehhplot} below provides the output of the function \texttt{xpehhplot} for the \emph{xpEHH} computed above across the CGU and EUT populations (see \ref{res.xpehh}). Figure \ref{fig:xpehhplot} was drawn using the following R code: + +```{r,eval=FALSE} +xpehhplot(cguVSeut.xpehh,plot.pval=TRUE) +``` + +```{r xpehhplot,echo=FALSE,fig.align='center',fig.ext="png",fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the \\texttt{xpehhplot()} function',fig.pos="!h"} +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "Rsb (CGU vs. EUT)"; cex.main = 1.;cex.axis=0.7 +data = cguVSeut.xpehh +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data[,3], pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(XPEHH)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +``` +###\emph{xpEHH} vs. \emph{Rsb} comparison: + +A plot of the \emph{xpEHH} against \emph{Rsb} estimates across the CGU and EUT populations (see \ref{res.xpehh} and \ref{res.rsb} respectively) is represented in the Figure \ref{fig:comp} below. This figure was generated using the following R code: + +```{r comp,echo=TRUE,fig.align='center',fig.ext="png",out.height="7cm",fig.lp='fig:',fig.cap='Comparison of the XPEHH and Rsb estimates across the CGU and EUT populations',fig.pos="!h"} +plot(cguVSeut.rsb[,3],cguVSeut.xpehh[,3],xlab="Rsb",ylab="XPEHH",pch=16, + cex=0.5,cex.lab=0.75,cex.axis=0.75) +abline(a=0,b=1,lty=2) +``` +##Visual inspection of the standardized scores distribution: the function \texttt{distribplot()} + +The \texttt{distribplot} function allows to easily visualize the distributions of the standardized scores (either \emph{iHS}, \emph{Rsb} or \emph{xpEHH}) and compare them to the standard Gaussian distribution. As an example, the Figure \ref{fig:distribplot} below provides the output the function \texttt{distribplot} when considering the \emph{iHS} estimates obtained for the CGU population (see \ref{cgu.ihs}) using the following R code: + +```{r,eval=FALSE} +distribplot(ihs.cgu$iHS[,3],xlab="iHS") +``` + +```{r distribplot,echo=FALSE,fig.align='center',fig.width=7,out.height="7cm",fig.height=7,fig.lp='fig:',fig.cap='Graphical output for the function \\texttt{distribplot}',fig.pos="!h"} +layout(matrix(1:2,2,1)) +data=ihs.cgu$iHS[,3] +lty = 1;lwd = 1.5;col = c("blue","red");main = "Genome-wide distribution";xlab = "iHS";cex.main = 1.5;cex.lab = 1.25;qqplot = TRUE +plot(density(data,na.rm = TRUE),main = main,xlab = xlab,col = col[1],lty = lty,lwd = lwd,cex.main = cex.main,cex.lab = cex.lab) + curve(dnorm,col = col[2],add = TRUE) + legend("topright",c("Observed","Gaussian"),bty = "n",col = col,lty = lty,lwd = lwd) + if (qqplot) { + par(mar = c(5,5,4,2) + 0.1) + qqnorm(data[!is.na(data)],cex.main = cex.main,cex.lab = cex.lab,pch = 16,cex = 0.75) + abline(a=0,b=1,lty=2) + } +``` + +#Visualizing haplotype structure around a core allele: the function \texttt{bifurcation.diagram()} + +The function \texttt{bifurcation.diagram()} function draws haplotype bifurcation diagrams [@Sabeti2002] that allow to better understand the origin of an observed footprints of selection. Such diagrams indeed consist in plotting the breakdown of LD at increasing distances from the core allele at the selected focal SNPs. The root (focal SNP) of each diagram is the core allele and is here identified by a vertical dashed line. +The diagram is bi-directional, portraying both centromere-proximal and centromere-distal LD. Moving in one direction, each marker is an opportunity for a node; the diagram either divides or not based on whether both or only one allele is present. Thus the breakdown of LD on the core haplotype background is portrayed at progressively longer distances. The thickness of the lines corresponds to the number of samples with the indicated long-distance haplotype. Several options are available to modify the aspect of the plots (see command \texttt{?bifurcation.diagram}) +As a matter of illustration, Figure \ref{fig:bifdia} shows the bifurcation diagrams for both the derived and ancestral alleles at the $456^{\text{th}}$ SNP on BTA12 CGU haplotypes. This SNP displayed a strong signal of selection (using both \emph{iHS} and \emph{Rsb} statistics) and is located closed (<5kb) to a strong candidate genes involved in horn development [@Gautier2011]. Figure \ref{fig:bifdia} was obtained with the following R code: + +```{r bifdia,eval=TRUE,fig.align='center',out.height="12cm",fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the function \\texttt{bifurcation.diagram()}',fig.pos="!h"} +data(haplohh_cgu_bta12) +layout(matrix(1:2,2,1)) +bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=1,nmrk_l=20,nmrk_r=20, + main="Bifurcation diagram (RXFP2 SNP on BTA12): Ancestral Allele") +bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=2,nmrk_l=20,nmrk_r=20, + main="Bifurcation diagram (RXFP2 SNP on BTA12): Derived Allele") +``` + +\clearpage +\newpage + +#References diff --git a/inst/doc/rehh.pdf b/inst/doc/rehh.pdf new file mode 100644 index 0000000..6d55581 Binary files /dev/null and b/inst/doc/rehh.pdf differ diff --git a/inst/map.inp b/inst/map.inp index e5bc89d..a20105c 100644 --- a/inst/map.inp +++ b/inst/map.inp @@ -1,44057 +1,44057 @@ -F0100190 1 113642 1 2 -F0100220 1 244699 1 2 -F0100250 1 369419 1 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+F2909760 29 49207370 C G +F2909770 29 49228426 G C +F2909780 29 49249117 A T +F2909790 29 49283331 T A +F2909810 29 49343218 C G +F2909820 29 49372169 G C +F2909830 29 49418545 A T +F2909840 29 49445944 T A +F2909850 29 49478413 C G +F2909860 29 49526792 G C +F2909870 29 49549643 A T +F2909880 29 49604955 T A +F2909890 29 49646267 C G +F2909900 29 49666811 G C +F2909910 29 49692970 A T +F2909920 29 49736787 T A +F2909930 29 49771264 C G +F2909940 29 49792764 G C +F2909950 29 49834478 A T +F2909960 29 49862475 T A +F2909970 29 49895145 C G +F2909980 29 49924570 G C +F2909990 29 49952069 A T +F2910000 29 49998680 T A +F2910010 29 50032868 C G +F2910020 29 50118683 G C +F2910030 29 50139261 A T +F2910040 29 50171073 T A +F2910050 29 50201659 C G +F2910060 29 50232014 G C +F2910080 29 50320455 A T +F2910100 29 50395796 T A +F2910110 29 50418453 C G +F2910120 29 50441548 G C +F2910130 29 50467838 A T +F2910140 29 50512108 T A +F2910150 29 50582453 C G +F2910160 29 50637074 G C +F2910170 29 50665297 A T +F2910180 29 50698391 T A +F2910200 29 50782045 C G +F2910210 29 50816341 G C +F2910240 29 50961598 A T +F2910250 29 51000623 T A +F2910260 29 51089107 C G +F2910280 29 51159869 G C +F2910290 29 51190293 A T +F2910300 29 51231973 T A +F2910310 29 51257883 C G +F2910320 29 51301848 G C +F2910330 29 51337489 A T +F2910340 29 51416372 T A +F2910360 29 51488691 C G +F2910370 29 51510473 G C +F2910380 29 51550213 A T +F2910390 29 51575404 T A +F2910400 29 51595527 C G +F2910410 29 51660774 G C +F2910430 29 51766334 A T +F2910440 29 51788032 T A +F2910450 29 51853783 C G +F2910460 29 51897597 G C +F2910480 29 51979344 A T diff --git a/man/calc_ehh.Rd b/man/calc_ehh.Rd index 5184d2a..a483348 100644 --- a/man/calc_ehh.Rd +++ b/man/calc_ehh.Rd @@ -3,8 +3,10 @@ \title{EHH and iHH computations at a given core SNP} \description{Compute Extended Haplotype Homozygosity (EHH) and integrated EHH (iHH) for a given focal SNPs.} \usage{ -calc_ehh(haplohh,mrk,limhaplo=2,limehh=0.05, -plotehh=TRUE,main_leg="EHH plot") +calc_ehh(haplohh, mrk, limhaplo = 2, limehh = 0.05, plotehh = TRUE, + lty = 1, lwd = 1.5, col = c("blue", "red"), xlab = "Position", + ylab = expression(Extended ~ haplotype ~ homozygosity ~ (italic(EHH))), + cex.lab = 1.25, main = NA, cex.main = 1.5) } \arguments{ \item{haplohh}{An object of class \code{haplohh} (see \code{data2haplohh}).} @@ -13,7 +15,14 @@ plotehh=TRUE,main_leg="EHH plot") haplotypes with missing data are removed from the computation. Hence as we compute EHH further from the core SNP, less haplotypes are expected} \item{limehh}{Limit below which EHH stops to be evaluated} \item{plotehh}{If TRUE, EHH estimates for both the ancestral and derived allele are plotted for each position} - \item{main_leg}{Legend of the EHH plot.} + \item{lty}{Line type for the ancestral and derived allele iHH (respectively) curves} + \item{lwd}{Line width for the ancestral and derived allele iHH (respectively) curves} + \item{col}{Color for the ancestral and derived allele iHH (respectively) curves} + \item{xlab}{Legend for the x--axis} + \item{ylab}{Legend for the y--axis} + \item{cex.lab}{Size of the axis legend} + \item{main}{Main legend of the EHHS plot} + \item{cex.main}{Size of the main legend} } \details{ @@ -31,12 +40,15 @@ in turn the computation of the integrated EHH relative to map distances (iHH). Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. - Sabeti, P.C. and Reich, D.E. and Higgins, J.M. and Levine, H.Z.P and Richter, D.J. and - Schaffner, S.F. and Gabriel, S.B. and Platko, J.V. and Patterson, N.J. and McDonald, G.J. - and Ackerman, H.C. and Campbell, S.J. and Altshuler, D. and Cooper, R. and Kwiatkowski, D. - and Ward, R. and Lander, E.S. (2002). Detecting recent positive selection in the human genome + Sabeti, P.C. et al. (2002). Detecting recent positive selection in the human genome from haplotype structure. \emph{Nature}, \bold{419}, 832--837. + Sabeti, P.C. et al. (2007). Genome-wide detection and characterization of positive selection in + human populations. \emph{Nature}, \bold{449}, 913--918. + + Tang, K. and Thornton, K.R. and Stoneking, M. (2007). A New Approach for Using Genome Scans + to Detect Recent Positive Selection in the Human Genome. \emph{Plos Biology}, \bold{7}, e171. + Voight, B.F. and Kudaravalli, S. and Wen, X. and Pritchard, J.K. (2006). A map of recent positive selection in the human genome. \emph{Plos Biology}, \bold{4}, e72. } diff --git a/man/calc_ehhs.Rd b/man/calc_ehhs.Rd index e8f0a84..a6b4314 100644 --- a/man/calc_ehhs.Rd +++ b/man/calc_ehhs.Rd @@ -3,8 +3,10 @@ \title{EHHS and iES computations at a given core SNP} \description{Compute site Extended Haplotype Homozygosity (EHHS) and integrated EHH (iES) for a given focal SNPs.} \usage{ -calc_ehhs(haplohh,mrk,limhaplo=2,limehhs=0.05, -plotehhs=TRUE,main_leg="EHHS plot") +calc_ehhs(haplohh, mrk, limhaplo = 2, limehhs = 0.05, plotehhs = TRUE, + lty = 1, lwd = 1.5, col = c("blue", "red"), xlab = "Position", + ylab = expression(Site ~ specific ~ italic(EHH) ~ (italic(EHHS))), + cex.lab = 1.25, main = NA, cex.main = 1.5) } \arguments{ \item{haplohh}{An object of class \code{haplohh} (see \code{data2haplohh}).} @@ -13,7 +15,14 @@ plotehhs=TRUE,main_leg="EHHS plot") haplotypes with missing data are removed from the computation. Hence as we compute EHH further from the core SNP, less haplotypes are expected} \item{limehhs}{Limit below which EHHS stops to be evaluated} \item{plotehhs}{If TRUE, EHHS estimates are plotted for each position} - \item{main_leg}{Legend of the EHHS plot} + \item{lty}{Line type for the EHHS_Sabeti_et_al_2007 and EHHS_Tang_et_al_2007 (respectively) curves} + \item{lwd}{Line width for the EHHS_Sabeti_et_al_2007 and EHHS_Tang_et_al_2007 (respectively) curves} + \item{col}{Color for the EHHS_Sabeti_et_al_2007 and EHHS_Tang_et_al_2007 (respectively) curves} + \item{xlab}{Legend for the x--axis} + \item{ylab}{Legend for the y--axis} + \item{cex.lab}{Size of the axis legend} + \item{main}{Main legend of the EHHS plot} + \item{cex.main}{Size of the main legend} } \details{ @@ -22,15 +31,19 @@ in turn the computation of the integrated EHHS relative to map distances (iES). } \value{ The returned value is a list containing the following components: - \item{ehhs}{A vector of nsnps columns containing EHHS estimates at each chromosome position relative to the focal SNP.} + \item{EHHS_Tang_et_al_2007}{A vector of nsnps columns containing EHHS estimates at each chromosome position relative to the focal SNP computed as described in the Tang et al. (2007).} + \item{EHHS_Sabeti_et_al_2007}{A vector of nsnps columns containing EHHS estimates at each chromosome position relative to the focal SNP computed as described in the Sabeti et al. (2007).} \item{nhaplo_eval}{A matrix of two rows and nsnps columns containing the number of evaluated haplotypes at each chromosome position relative to the focal SNP for the ancestral (first row) and derived (second row) alleles.} - \item{freqall1}{Frequency of the ancestral allele matrix for the focal SNP.} - \item{ies}{Integrated EHHS (IES) over the chromosome.} + \item{IES_Sabeti_et_al_2007}{Integrated EHHS (computed using the estimator by Sabeti et al. (2007)) over the chromosome.} + \item{IES_Tang_et_al_2007}{Integrated EHHS (computed using the estimator by Tang et al. (2007)) over the chromosome.} } \references{ Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. + Sabeti, P.C. et al. (2007). Genome-wide detection and characterization of positive selection in + human populations. \emph{Nature}, \bold{449}, 913--918. + Tang, K. and Thornton, K.R. and Stoneking, M. (2007). A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome. \emph{Plos Biology}, \bold{7}, e171. diff --git a/man/data2haplohh.Rd b/man/data2haplohh.Rd index 82ba6ab..8b62b2a 100644 --- a/man/data2haplohh.Rd +++ b/man/data2haplohh.Rd @@ -4,32 +4,42 @@ \description{Converts input file data into an object of class haplohh.} \usage{ data2haplohh(hap_file,map_file,min_maf=0,min_perc_geno.hap=100, -min_perc_geno.snp=100,chr.name=NA,popsel=NA,recode.allele=FALSE) +min_perc_geno.snp=100,chr.name=NA,popsel=NA,recode.allele=FALSE, +haplotype.in.columns=FALSE) } \arguments{ \item{hap_file}{Path to the file containing haplotype data (see details section below for information about input file format)} \item{map_file}{Path to the file containing map information (see details section below for information about input file format} - \item{min_maf}{Threshold on Minor Allele Frequency (SNPs displaying a MAF<\code{min_maf} are discarded)} - \item{min_perc_geno.hap}{Threshold on percentage of missing data for haplotypes (Haplotypes with less than \code{min_perc_geno.hap} percent SNPs genotyped are discarded)} - \item{min_perc_geno.snp}{Threshold on percentage of missing data for SNPs (SNPs genotyped on less than \code{min_perc_geno.snp} percent haplotypes are discarded)} + \item{min_maf}{Threshold on Minor Allele Frequency (SNPs displaying a MAF lower than \code{min_maf} are discarded)} + \item{min_perc_geno.hap}{Threshold on percentage of missing data for haplotypes (Haplotypes with less than \code{min_perc_geno.hap} percent SNPs genotyped are discarded). By default, \code{min_perc_geno.hap}=100, hence only fully genotyped haplotypes are retained} + \item{min_perc_geno.snp}{Threshold on percentage of missing data for SNPs (SNPs genotyped on less than \code{min_perc_geno.snp} percent haplotypes are discarded). By default, \code{min_perc_geno.snp}=100, hence only fully genotyped SNPs are retained} \item{chr.name}{Name of the chromosome considered (relevant if several chromosomes are represented in the map file)} \item{popsel}{Code of the population considered in the fastPHASE output haplotype file (relevant if \code{hap_file} is a fastPHASE output and haplotypes originate from different population)} \item{recode.allele}{If TRUE, allele in the haplotypes are recoded according to the map file information. If FALSE a rough verification is performed to check only 0 (code for missing data), 1 (code for ancestral allele) or 2 (code for derived allele) are present in the haplotype file} + \item{haplotype.in.columns}{If TRUE, phased input haplotypes are assumed to be in columns (as produced by the SHAPEIT2 program (O'Connell et al., 2014). +} } \details{ -Two haplotype input formats are supported: i) a standard format with haplotype in row and snps in column (with no header and a haplotype id) and ii) output files from fastPHASE program (Sheet and Stephens, 2006). The function automatically checks if the file is in fastPHASE output format. In this latter case, if haplotypes originate from several different population were phased simultaneously (-u fastPHASE option was used), the function ask interactively which population should be considered (a list of population number are proposed) unless specified with the \code{popsel} argument. +Three haplotype input formats are supported: i) a standard format with haplotype in row and snps in column (with no header and a haplotype id); ii) a (transposed) format similar to the one produced by the phasing program SHAPEIT2 program (O'Connell et al., 2014) in which haplotypes are in columns and snps in rows (with no header and no snp id); and iii) output files from fastPHASE program (Sheet and Stephens, 2006). If the input haplotypes are not in transposed format (i.e., \code{haplotype.in.columns} is FALSE, as by default), the function automatically checks if the file is in fastPHASE output format. In this latter case, if haplotypes originate from several different population were phased simultaneously (-u fastPHASE option was used), the function ask interactively which population should be considered (a list of population number are proposed) unless specified with the \code{popsel} argument. Map file contains SNPs information in five columns SNP names, chromosome, position, ancestral and derived allele. SNPs must be in the same order as in the haplotype for the chromosome considered. If several chromosomes are represented in the map file, one can provide the name of the chromosome of interest (corresponding to the haplotype under study) with \code{chr.name} argument. Haplotype are recoded (if \code{recode.allele} option is activated) according to the ancestral and derived allele definition available in the map file (fourth and fifth columns) as :0=missing data, 1=ancestral allele, 2=derived allele. If such a coding is detected, no recoding is performed. Note that Rsb statistics does not consider ancestral and derived allele status information. Finally, the arguments \code{min\_perc\_geno.hap}, \code{min\_perc\_geno.snp} and \code{min\_maf} are evaluated in this order. } \value{The returned value is an object of class haplohh} +\references{ + Scheet P, Stephens M (2006) A fast and flexible statistical model for large-scale population genotype data: + applications to inferring missing genotypes and haplotypic phase. \emph{Am J Hum Genet}, \bold{78}, 629-644. + + O'Connell J, Gurdasani D, Delaneau O, et al (2014) A general approach for haplotype phasing across + the full spectrum of relatedness. \emph{PLoS Genet}, \bold{10}, e1004234. +} \seealso{calc_ehh,calc_ehhs,scan_hh,make.example.files} \examples{ #Copy example files in the current working directory. make.example.files() #using the fastPHASE output haplotype example file hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", -min_maf=0.05,popsel=7,chr.name=12) +min_maf=0.05,popsel=7,chr.name=12,recode.allele=TRUE) #using the standard output haplotype example file hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", -min_maf=0.05,chr.name=12) +min_maf=0.05,chr.name=12,recode.allele=TRUE) } diff --git a/man/distribplot.Rd b/man/distribplot.Rd index 19ee374..7dc1a30 100644 --- a/man/distribplot.Rd +++ b/man/distribplot.Rd @@ -1,23 +1,29 @@ \name{distribplot} \alias{distribplot} \title{Distribution of standardized iHS or Rsb values} -\description{Plot the observed distribution of standardized iHS or Rsb values together with the expected standard Gaussian distribution} +\description{Plot the observed distribution of standardized iHS or Rsb values together + with the expected standard Gaussian distribution} \usage{ -distribplot(data,col=c("blue","red"), -main="iHS distribution",xlab="iHS") +distribplot(data,lty = 1,lwd = 1.5,col = c("blue","red"), +main = "Genome-wide distribution",xlab = "",cex.main = 1.5,cex.lab = 1.25,qqplot = TRUE) } \arguments{ - \item{data}{A vector of iHS or Rsb values.} + \item{data}{A vector of iHS, Rsb or XPEHH values.} \item{col}{A vector describing color of the Observed and expected Gaussian distribution} \item{main}{Character string for the plot legend} \item{xlab}{Character string for the X-axis legend} + \item{cex.lab}{Size of axis legends} + \item{cex.main}{Size of the main legend} + \item{lty}{Line Type} + \item{lwd}{Line Width} + \item{qqplot}{If TRUE a qq-plot is drawn} } \value{The function returns a plot.} -\seealso{scan_hh,ihh2ihs,ies2rsb,ihsplot,rsbplot} +\seealso{scan_hh,ihh2ihs,ies2rsb,ihsplot,rsbplot,ies2xpehh,xpehhplot} \examples{ data(wgscan.cgu) ## results from a genome scan (44,057 SNPs) see ?wgscan.eut for details -val.ihs<-ihh2ihs(wgscan.cgu)$res.ihs[,3] +val.ihs<-ihh2ihs(wgscan.cgu)$iHS[,3] ##standardize distribplot(val.ihs,main="iHS (CGU population)") dev.off() diff --git a/man/haplohh-class.Rd b/man/haplohh-class.Rd index 33c5527..6a8d62e 100644 --- a/man/haplohh-class.Rd +++ b/man/haplohh-class.Rd @@ -16,7 +16,7 @@ Objects can be created by calls of the form \code{new("haplohh", ...)}. \item{\code{haplo}}{Object of class \code{"matrix"}: haplotypes with alleles coded as 0 (missing data), 1 (ancestral allele) or 2 (derived allele)} \item{\code{position}}{Object of class \code{"numeric"}:position of the SNPs in the chromosome} \item{\code{snp.name}}{Object of class \code{"character"}:names of the SNP} - \item{\code{chr.name}}{Object of class \code{"numeric"}:name of the chromosome SNPs are mapping to} + \item{\code{chr.name}}{Object of class \code{"character"}:name of the chromosome SNPs are mapping to} \item{\code{nhap}}{Object of class \code{"numeric"}:number of haplotypes} \item{\code{nsnp}}{Object of class \code{"numeric"}:number of SNPs in the haplotypes} } diff --git a/man/ies2rsb.Rd b/man/ies2rsb.Rd index ce50dbd..de7c228 100644 --- a/man/ies2rsb.Rd +++ b/man/ies2rsb.Rd @@ -11,7 +11,7 @@ \item{method}{Either "bilateral" or "unilateral". If bilateral (resp. unilateral), pvalue (assuming Rsb follows a standard Gaussian distribution under neutrality) corresponds to a bilateral (resp. unilateral) tests} } -\details{Ratio of iES (population 1 over population 2) standardized as described in Tang et al. (2007)} +\details{Ratio of iES (population 1 over population 2) computed and standardized as described in Tang et al. (2007)} \value{ The returned value is a matrix with nsnps rows and four columns (Chromosome name, position of the SNP, Rsb and Pvalue) } diff --git a/man/ies2xpehh.Rd b/man/ies2xpehh.Rd new file mode 100644 index 0000000..5808a24 --- /dev/null +++ b/man/ies2xpehh.Rd @@ -0,0 +1,31 @@ +\name{ies2xpehh} +\alias{ies2xpehh} +\title{Compute xpEHH (standardized ratio of iES from two populations) as described in Sabeti et al. (2007)} +\description{Compute xpEHH (standardized ratio of iES from two populations) as described in Sabeti et al. (2007).} +\usage{ies2xpehh(hh_pop1,hh_pop2,popname1=NA,popname2=NA,method="bilateral")} +\arguments{ + \item{hh_pop1}{A matrix with nsnps rows and six columns (Chromosome name, position of the SNP, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele and iES) obtained after performing a scan on the first population.} + \item{hh_pop2}{A matrix with nsnps rows and six columns (Chromosome name, position of the SNP, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele and iES) obtained after performing a scan on the second population.} + \item{popname1}{Name of the first population compared (character string).} + \item{popname2}{Name of the second population compared (character string).} + \item{method}{Either "bilateral" or "unilateral". If bilateral (resp. unilateral), pvalue (assuming Rsb follows a standard Gaussian distribution under neutrality) corresponds to a bilateral (resp. unilateral) tests} +} + +\details{Ratio of iES (population 1 over population 2) computed and standardized as described in Sabeti et al. (2007)} +\value{ + The returned value is a matrix with nsnps rows and four columns (Chromosome name, position of the SNP, xpEHH and Pvalue) +} +\references{ + Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World + Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. + + Sabeti, P.C. et al. (2007). Genome-wide detection and characterization of positive selection in + human populations. \emph{Nature}, \bold{449}, 913--918. +} +\seealso{calc_ehhs,scan_hh,distribplot,rsbplot} +\examples{ +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) +##see ?wgscan.eut and ?wgscan.cgu for details +xpehh<-ies2xpehh(wgscan.cgu,wgscan.eut,"CGU","EUT") +} diff --git a/man/ihh2ihs.Rd b/man/ihh2ihs.Rd index 2660763..bebfb86 100644 --- a/man/ihh2ihs.Rd +++ b/man/ihh2ihs.Rd @@ -4,7 +4,7 @@ \description{Compute iHS (standardized iHH).} \usage{ihh2ihs(res_ihh,freqbin=0.025,minmaf=0.05)} \arguments{ - \item{res_ihh}{A matrix with nsnps rows and six columns (Chromosome name, position of the SNP, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele and iES) obtained after performing a scan on the population of interest.} + \item{res_ihh}{A dataframe with nsnps rows and seven columns as obtained from the \code{scan_hh} function applied to the population of interest.} \item{freqbin}{Size of the bin to standardize log(iHH1/iHH2) according to the underlying Derived Allele frequency. Allele frequency bins vary from \code{minmaf} to 1-\code{minmaf} per step of size \code{freqbin}. If \code{freqbin} is set to 0 (e.g. in the case of a large number of SNPs and few haplotypes), standardization is performed considering each observed frequency as a frequency class. } @@ -13,8 +13,8 @@ \details{iHS (standardized iHH) are standardized as described in Voight et al. (2006)} \value{ The returned value is a list containing two elements - \item{res.ihs}{matrix with nsnps rows and four columns (Chromosome name, position of the SNP, Rsb and Pvalue)} - \item{summary.class}{matrix with nclasses rows and four columns (Class, Number of SNPs belonging to this class,position of the SNP, mean iHH in this class, standard deviation of iHH in this class)} + \item{res.ihs}{a dataframe with nsnps rows and four columns (Chromosome name, position of the SNP, iHS and Pvalue in a log10 scale)} + \item{summary.class}{matrix with nclasses rows and three columns (Number of SNPs belonging to this class,position of the SNP, mean iHH in this class, standard deviation of iHH in this class)} } \references{ Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World diff --git a/man/ihsplot.Rd b/man/ihsplot.Rd index d5b4eef..1096e1f 100644 --- a/man/ihsplot.Rd +++ b/man/ihsplot.Rd @@ -2,24 +2,33 @@ \alias{ihsplot} \title{Plot iHS over a genome} \description{Plot iHS over a genome.} -\usage{ihsplot(data,plot.pval="TRUE",ylim.scan=2,pch=16,main="iHS")} +\usage{ihsplot(ihsdata,plot.pval = TRUE,ylim.scan = 2,pch = 16,cex = 0.5,cex.lab = 1.25, +main = NA,cex.main = 1.5,cex.axis=1.)} \arguments{ - \item{data}{A matrix with nsnps rows and 4 columns (Chromosome name, position of the SNP, iHS, Pvalue) (e.g. obtained using \code{ihh2ihs} function.} + \item{ihsdata}{A list obtained with the \code{ihh2ihs} function.} \item{plot.pval}{Either TRUE or FALSE if Pvalue should not be plotted} - \item{ylim.scan}{An horizontal line is added at the corresponding coordinate, for instance to represent a significance threshold} + \item{ylim.scan}{An horizontal line is added at the corresponding coordinate, for + instance to represent a significance threshold} \item{pch}{Type of the points representing SNPs in the plot(s)} + \item{cex}{Size of the points representing SNPs in the plot(s)} + \item{cex.lab}{Size of axis legends} \item{main}{Main Legend of the plot} + \item{cex.main}{Size of the main legend} + \item{cex.axis}{Size of the axis annotations} } \value{The function returns a plot} \references{ Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. + + Voight, B.F. and Kudaravalli, S. and Wen, X. and Pritchard, J.K. (2006). + A map of recent positive selection in the human genome. \emph{Plos Biology}, \bold{4}, e72. } -\seealso{calc_ehh,scan_hh,distribplot,ihsplot} +\seealso{ihh2ihs} \examples{ data(wgscan.cgu) ## results from a genome scan (44,057 SNPs) ##see ?wgscan.eut and ?wgscan.cgu for details res.ihs<-ihh2ihs(wgscan.cgu) -ihsplot(res.ihs$res.ihs) +ihsplot(res.ihs) } diff --git a/man/rehh-package.Rd b/man/rehh-package.Rd index 7d8f5fb..65ec879 100644 --- a/man/rehh-package.Rd +++ b/man/rehh-package.Rd @@ -11,7 +11,7 @@ Functions for the detection of footprints of selection on dense SNP data using E \details{ \tabular{ll}{ Package: \tab rehh\cr -Version: \tab 1.1\cr +Version: \tab 2.0.0\cr License: \tab GPL(>=2)\cr Depends: \tab gplots , methods\cr } @@ -27,14 +27,17 @@ calc_ehhs EHHS and iES computations at a data2haplohh Converting data into an object of class haplohh distribplot Distribution of standardized - iHS or Rsb values + iHS, Rsb or XP-EHH values haplohh_cgu_bta12 Example of an 'haplohh' object ies2rsb Compute Rsb (standardized ratio of iES from two populations) +ies2xpehh Compute XP-EHH (standardized ratio of + iES from two populations) ihh2ihs Compute iHS (standardized iHH) ihsplot Plot iHS over a genome make.example.files Generate example input files rsbplot Plot Rsb over a genome +xpehhplot Plot XP-EHH over a genome scan_hh Computing EHH based statistics over a whole chromosome wgscan.cgu Whole genome scan results for the CGU @@ -44,7 +47,10 @@ wgscan.eut Whole genome scan results for a pool of } } \references{ - Gautier, M. and Vitalis, R. (2012). rehh: An R package to detect footprints of + Gautier M., Klassmann A., and Vitalis R. (2016). rehh: An R package to detect footprints of selection in genome-wide SNP data from haplotype structure. + \emph{Molecular Ecology Resources}, submitted + + Gautier M. and Vitalis R. (2012). rehh: An R package to detect footprints of selection in genome-wide SNP data from haplotype structure. \emph{Bioinformatics}, \bold{28}(8), 1176--1177. } \keyword{ package } diff --git a/man/rsbplot.Rd b/man/rsbplot.Rd index 13c2588..43b894a 100644 --- a/man/rsbplot.Rd +++ b/man/rsbplot.Rd @@ -2,25 +2,33 @@ \alias{rsbplot} \title{Plot Rsb over a genome} \description{Plot Rsb over a genome.} -\usage{rsbplot(data,plot.pval="TRUE",ylim.scan=2,pch=16,main=NA)} +\usage{rsbplot(data,plot.pval = TRUE,ylim.scan = 2,pch = 16,cex = 0.5,cex.lab = 1.25, +main = NA,cex.main = 1.5,cex.axis=1.)} \arguments{ - \item{data}{A matrix with nsnps rows and 4 columns (Chromosome name, position of the SNP, Rsb, Pvalue (either unilateral or bilateral)) (e.g. obtained using \code{ies2rsb} function.} + \item{data}{A dataframe obtained using \code{ies2rsb} function.} \item{plot.pval}{Either TRUE or FALSE if Pvalue should not be plotted} \item{ylim.scan}{An horizontal line is added at the corresponding coordinate, for instance to represent a significance threshold} \item{pch}{Type of the points representing SNPs in the plot(s)} + \item{cex}{Size of the points representing SNPs in the plot(s)} + \item{cex.lab}{Size of axis legends} \item{main}{Main Legend of the plot} + \item{cex.main}{Size of the main legend} + \item{cex.axis}{Size of the axis annotations} } \value{The function returns a plot} \references{ Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. + + Tang, K. and Thornton, K.R. and Stoneking, M. (2007). A New Approach for Using Genome Scans + to Detect Recent Positive Selection in the Human Genome. \emph{Plos Biology}, \bold{7}, e171. } -\seealso{calc_ehhs,scan_hh,distribplot,ihsplot} +\seealso{ies2rsb} \examples{ data(wgscan.cgu) ; data(wgscan.eut) ## results from a genome scan (44,057 SNPs) #see ?wgscan.eut and ?wgscan.cgu for details res.rsb<-ies2rsb(wgscan.cgu,wgscan.eut,"CGU","EUT") -rsbplot(res.rsb$res.rsb) +rsbplot(res.rsb) } diff --git a/man/scan_hh.Rd b/man/scan_hh.Rd index f699fbe..efc9de8 100644 --- a/man/scan_hh.Rd +++ b/man/scan_hh.Rd @@ -2,33 +2,34 @@ \alias{scan_hh} \title{Computing EHH based statistics over a whole chromosome} \description{Compute Extended Haplotype Homozygosity (EHH), site-specific EHH (EHHS), integrated EHH (iHH) and integrated EHHS (iES) for all SNPs of the chromosome (or linkage group).} -\usage{scan_hh(haplohh,limhaplo=2,limehh=0.05,limehhs=0.05)} +\usage{scan_hh(haplohh,limhaplo=2,limehh=0.05,limehhs=0.05,threads=1)} \arguments{ \item{haplohh}{An object of class \code{haplohh} (see \code{data2haplohh}).} \item{limhaplo}{Minimal number of haplotypes to continue computing EHH away from the core SNP. Useless, if no missing data. However, when some data are missing, haplotypes with missing data are removed from the computation. Hence as we compute EHH further from the core SNP, less haplotypes are expected} \item{limehh}{Limit below which EHH stops to be evaluated} \item{limehhs}{Limit below which EHHS stops to be evaluated} + \item{threads}{Number of threads to parallelize compuation} } \details{ Extended Haplotype Homozygosity (EHH), site-specific EHH (EHHS), integrated EHH (iHH) and integrated EHHS (iES) are computed for all SNPs of the chromosome (or linkage group). - This function is approximately twice as faster as a procedure calling in turn \code{calc_ehh} and \code{calc_ehhs} for all the SNP. To perform a whole genome-scan + This function is several times faster as a procedure calling in turn \code{calc_ehh} and \code{calc_ehhs} for all the SNP. To perform a whole genome-scan this function needs to be called for each chromosome and results concatenated. } \value{ - The returned value is a matrix with nsnps rows and six columns (Chromosome name, position of the SNP, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele and iES) + The returned value is a dataframe with nsnps rows and seven columns (Chromosome name, position of the SNP, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele, iES using the estimator by Sabeti et al. (2007) estimator and iES using the estimator by Tang et al. (2007)) } \references{ Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. - Sabeti, P.C. and Reich, D.E. and Higgins, J.M. and Levine, H.Z.P and Richter, D.J. and - Schaffner, S.F. and Gabriel, S.B. and Platko, J.V. and Patterson, N.J. and McDonald, G.J. - and Ackerman, H.C. and Campbell, S.J. and Altshuler, D. and Cooper, R. and Kwiatkowski, D. - and Ward, R. and Lander, E.S. (2002). Detecting recent positive selection in the human genome + Sabeti, P.C. et al. (2002). Detecting recent positive selection in the human genome from haplotype structure. \emph{Nature}, \bold{419}, 832--837. + Sabeti, P.C. et al. (2007). Genome-wide detection and characterization of positive selection in + human populations. \emph{Nature}, \bold{449}, 913--918. + Tang, K. and Thornton, K.R. and Stoneking, M. (2007). A New Approach for Using Genome Scans to Detect Recent Positive Selection in the Human Genome. \emph{Plos Biology}, \bold{7}, e171. diff --git a/man/wgscan.cgu.Rd b/man/wgscan.cgu.Rd index 9f3671d..92da80c 100644 --- a/man/wgscan.cgu.Rd +++ b/man/wgscan.cgu.Rd @@ -6,7 +6,7 @@ \description{ - A matrix of 44,057 rows (SNPs) and 6 columns (Chromosome name, position of the SNP in bp, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele and iES). + A dataframe object with of 44,057 rows (SNPs) and 7 columns: i) chromosome name (CHR), ii) position of the SNP in bp (POSITION), iii) Ancestral allele frequency (freq_A), iv) iHH for the ancestral allele (iHH_A), v) iHH for the derived allele (iHH_D), vi) iES using the estimator by Tang et al. (2007) (iES_Tang_et_al_2007), vii) iES using the estimator by Sabeti et al. (2007) (iES_Sabeti_et_al_2007). } \usage{data(wgscan.cgu)} diff --git a/man/wgscan.eut.Rd b/man/wgscan.eut.Rd index e2e365d..c70a1ef 100644 --- a/man/wgscan.eut.Rd +++ b/man/wgscan.eut.Rd @@ -2,11 +2,11 @@ \alias{wgscan.eut} \docType{data} -\title{Whole genome scan results for a pooled of European taurine cattle} +\title{Whole genome scan results for a pool of European taurine cattle} \description{ - A matrix of 44,057 rows (SNPs) and 6 columns (Chromosome name, position of the SNP in bp, Frequency of the ancestral allele, iHH for the ancestral allele, iHH for the derived allele and iES). + A dataframe object with 44,057 rows (SNPs) and 7 columns: i) chromosome name (CHR), ii) position of the SNP in bp (POSITION), iii) Ancestral allele frequency (freq_A), iv) iHH for the ancestral allele (iHH_A), v) iHH for the derived allele (iHH_D), vi) iES using the estimator by Tang et al. (2007) (iES_Tang_et_al_2007), vii) iES using the estimator by Sabeti et al. (2007) (iES_Sabeti_et_al_2007). } \usage{data(wgscan.eut)} diff --git a/man/xpehhplot.Rd b/man/xpehhplot.Rd new file mode 100644 index 0000000..6785e0b --- /dev/null +++ b/man/xpehhplot.Rd @@ -0,0 +1,34 @@ +\name{xpehhplot} +\alias{xpehhplot} +\title{Plot XPEHH over a genome} +\description{Plot XPEHH over a genome.} +\usage{xpehhplot(data,plot.pval = TRUE,ylim.scan = 2,pch = 16,cex = 0.5,cex.lab = 1.25, +main = NA,cex.main = 1.5,cex.axis=1.)} + +\arguments{ + \item{data}{A dataframe obtained using \code{ies2xpehh} function.} + \item{plot.pval}{Either TRUE or FALSE if Pvalue should not be plotted} + \item{ylim.scan}{An horizontal line is added at the corresponding coordinate, for instance to represent a significance threshold} + \item{pch}{Type of the points representing SNPs in the plot(s)} + \item{cex}{Size of the points representing SNPs in the plot(s)} + \item{cex.lab}{Size of axis legends} + \item{main}{Main Legend of the plot} + \item{cex.main}{Size of the main legend} + \item{cex.axis}{Size of the axis annotations} +} +\value{The function returns a plot} +\references{ + Gautier, M. and Naves, M. (2011). Footprints of selection in the ancestral admixture of a New World + Creole cattle breed. \emph{Molecular Ecology}, \bold{20}, 3128--3143. + + Sabeti, P.C. et al. (2007). Genome-wide detection and characterization of positive selection in + human populations. \emph{Nature}, \bold{449}, 913--918. +} +\seealso{ies2xpehh} +\examples{ +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) +#see ?wgscan.eut and ?wgscan.cgu for details +res.xpehh<-ies2xpehh(wgscan.cgu,wgscan.eut,"CGU","EUT") +xpehhplot(res.xpehh) +} diff --git a/src/CALL_EHH.c b/src/CALL_EHH.c new file mode 100644 index 0000000..c116745 --- /dev/null +++ b/src/CALL_EHH.c @@ -0,0 +1,56 @@ +#include +#include "hh_utils.h" + +void CALL_EHH(int *Rdata, + int *focl_snp, + int *nbr_snps, + int *nbr_chrs, + int *tot_nbr_hapl, + int *min_nbr_hapl, + double *min_ehh, + double *map, + double *ehh, + double *ihh) + +{ + int i,j; + short int **data; + + *focl_snp -= 1; // This is to account for C numbering of arrays + data = (short int **) malloc(*nbr_chrs * sizeof(short int *)); // Create a `data' array (nbr_chrs x nbr_snps) for C code + for (i = 0; i < *nbr_chrs; i++) { + data[i] = (short int *) malloc(*nbr_snps * sizeof(short int)); + } + for (i = 0; i < *nbr_chrs; i++) { // Copy information from the `Rdata' vector into the `data' array + for (j = 0; j < *nbr_snps; j++) { + switch (Rdata[(j * *nbr_chrs) + i]) { + + case 0: + data[i][j] = MISSING; // missing data is encoded as `0' in the `Rdata' vector, and as MISSING (= `9') in the `data' array + break; + + case 1: + data[i][j] = ANCSTRL; // ancestral allele is encoded as `1' in the `Rdata' vector, and as ANCSTRL (= `0') in the `data' array + break; + + case 2: + data[i][j] = DERIVED; // derived allele is encoded as `2' in the `Rdata' vector, and as DERIVED (= `1') in the `data' array + break; + + } + } + } + for (j = 0; j < 2 * *nbr_snps; j++) { + ehh[j] = 0.0; // Initialize the `ehh' vector + tot_nbr_hapl[j] = 0; // Initialize the total number of haplotypes [N.B: might be unnecessary, tot_nbr_hapl[focl_snp] = 0; should be sufficient...] + } + compute_ehh(data,*focl_snp,ANCSTRL,*nbr_snps,*nbr_chrs,tot_nbr_hapl,*min_nbr_hapl,*min_ehh,ehh); // compute the EHH for the ancestral allele + compute_ehh(data,*focl_snp,DERIVED,*nbr_snps,*nbr_chrs,tot_nbr_hapl + *nbr_snps,*min_nbr_hapl,*min_ehh,ehh + *nbr_snps); // compute the EHH for the derived allele + ihh[ANCSTRL] = integrate(map,ehh,*nbr_snps,*min_ehh); // compute the IHH for the ancestral allele + ihh[DERIVED] = integrate(map,ehh + *nbr_snps,*nbr_snps,*min_ehh); // compute the IHH for the derived allele + for (i = 0; i < *nbr_chrs; i++) { // Free the memory for the `data' array + free(data[i]); + } + free(data); +} + diff --git a/src/CALL_EHHS.c b/src/CALL_EHHS.c new file mode 100644 index 0000000..a0e1d41 --- /dev/null +++ b/src/CALL_EHHS.c @@ -0,0 +1,57 @@ +#include +#include "hh_utils.h" + +void CALL_EHHS(int *Rdata, + int *focl_snp, + int *nbr_snps, + int *nbr_chrs, + int *tot_nbr_hapl, + int *min_nbr_hapl, + double *min_ehhs, + double *map, + double *ehhs_tang, + double *ies_tang, + double *ehhs_sabeti, + double *ies_sabeti) + +{ + int i,j; + short int **data; + + *focl_snp -= 1; // This is to account for C numbering of arrays + data = (short int **) malloc(*nbr_chrs * sizeof(short int *)); // Create a `data' array (nbr_chrs x nbr_snps) for C code + for (i = 0; i < *nbr_chrs; i++) { + data[i] = (short int *) malloc(*nbr_snps * sizeof(short int)); + } + for (i = 0; i < *nbr_chrs; i++) { // Copy information from the `Rdata' vector into the `data' array + for (j = 0; j < *nbr_snps; j++) { + switch (Rdata[(j * *nbr_chrs) + i]) { + + case 0: + data[i][j] = MISSING; // missing data is encoded as `0' in the `Rdata' vector, and as MISSING (= `9') in the `data' array + break; + + case 1: + data[i][j] = ANCSTRL; // ancestral allele is encoded as `1' in the `Rdata' vector, and as ANCSTRL (= `0') in the `data' array + break; + + case 2: + data[i][j] = DERIVED; // derived allele is encoded as `2' in the `Rdata' vector, and as DERIVED (= `1') in the `data' array + break; + + } + } + } + for (j = 0; j < *nbr_snps; j++) { + ehhs_tang[j] = 0.0; // Initialize the `ehhs_tang' vector, for Tang et al.'s (2007) definition + ehhs_sabeti[j] = 0.0; // Initialize the `ehhs_sabeti' vector, for Sabeti et al.'s (2007) definition + tot_nbr_hapl[j] = 0; // Initialize the total number of haplotypes [N.B: might be unnecessary, tot_nbr_hapl[focl_snp] = 0; should be sufficient...] + } + compute_ehhs(data,*focl_snp,*nbr_snps,*nbr_chrs,tot_nbr_hapl,*min_nbr_hapl,*min_ehhs,ehhs_tang,ehhs_sabeti); // compute the EHHS for both Tang et al.'s (2007) and Sabeti et al.'s (2007) definitions + *ies_tang = integrate(map,ehhs_tang,*nbr_snps,*min_ehhs); // compute the IES, for Tang et al.'s (2007) definition + *ies_sabeti = integrate(map,ehhs_sabeti,*nbr_snps,*min_ehhs); // compute the IES, for Sabeti et al.'s (2007) definition + for (i = 0; i < *nbr_chrs; i++) { // Free the memory for the `data' array + free(data[i]); + } + free(data); +} diff --git a/src/CALL_SCAN_HH.c b/src/CALL_SCAN_HH.c new file mode 100644 index 0000000..2da247c --- /dev/null +++ b/src/CALL_SCAN_HH.c @@ -0,0 +1,103 @@ +#include +#ifdef _OPENMP +#include +#endif +#include "hh_utils.h" + +void CALL_SCAN_HH(int *Rdata, + int *nbr_snps, + int *nbr_chrs, + int *min_nbr_hapl, + double *min_ehh, + double *min_ehhs, + double *map, + double *ihh_vect, + double *ies_tang_vect, + double *ies_sabeti_vect, + int *nbr_threads) + +{ + int i,j; + int idx_thread; + short int **data; + int **tot_nbr_hapl; + double **ehh,**ehhs_tang,**ehhs_sabeti; + + tot_nbr_hapl = (int **) malloc(*nbr_threads * sizeof(int *)); // Allocate memory for thread-specific vectors + ehh = (double **) malloc(*nbr_threads * sizeof(double *)); + ehhs_tang = (double **) malloc(*nbr_threads * sizeof(double *)); + ehhs_sabeti = (double **) malloc(*nbr_threads * sizeof(double *)); + for (i = 0; i < *nbr_threads; i++) { + tot_nbr_hapl[i] = (int *) malloc(*nbr_snps * sizeof(int)); + ehh[i] = (double *) malloc(*nbr_snps * sizeof(double)); + ehhs_tang[i] = (double *) malloc(*nbr_snps * sizeof(double)); + ehhs_sabeti[i] = (double *) malloc(*nbr_snps * sizeof(double)); + } + data = (short int **) malloc(*nbr_chrs * sizeof(short int *)); // Create a `data' array (nbr_chrs x nbr_snps) for C code + for (i = 0; i < *nbr_chrs; i++) { + data[i] = (short int *) malloc(*nbr_snps * sizeof(short int)); + } + for (i = 0; i < *nbr_chrs; i++) { // Copy information from the `Rdata' vector into the `data' array + for (j = 0; j < *nbr_snps; j++) { + switch (Rdata[(j * *nbr_chrs) + i]) { + + case 0: + data[i][j] = MISSING; // missing data is encoded as `0' in the `Rdata' vector, and as MISSING (= `9') in the `data' array + break; + + case 1: + data[i][j] = ANCSTRL; // ancestral allele is encoded as `1' in the `Rdata' vector, and as ANCSTRL (= `0') in the `data' array + break; + + case 2: + data[i][j] = DERIVED; // derived allele is encoded as `2' in the `Rdata' vector, and as DERIVED (= `1') in the `data' array + break; + + } + } + } +#ifdef _OPENMP +#pragma omp parallel for num_threads(*nbr_threads) private(i,idx_thread) +#endif + for (j = 0; j < *nbr_snps; j++) { +#ifdef _OPENMP + idx_thread = omp_get_thread_num(); +#else + idx_thread = 0; +#endif + for (i = 0; i < *nbr_snps; i++) { + ehh[idx_thread][i] = 0.0; // Initialize the `ehh' vector + tot_nbr_hapl[idx_thread][i] = 0; // Initialize the total number of haplotypes [N.B: might be unnecessary, tot_nbr_hapl[j] = 0; should be sufficient...] + } + compute_ehh(data,j,ANCSTRL,*nbr_snps,*nbr_chrs,tot_nbr_hapl[idx_thread],*min_nbr_hapl,*min_ehh,ehh[idx_thread]); // compute the EHH for the ancestral allele + ihh_vect[j] = integrate(map,ehh[idx_thread],*nbr_snps,*min_ehh); // compute the IHH for the ancestral allele + for (i = 0; i < *nbr_snps; i++) { + ehh[idx_thread][i] = 0.0; // Initialize the `ehh' vector + tot_nbr_hapl[idx_thread][i] = 0; // Initialize the total number of haplotypes [N.B: might be unnecessary, tot_nbr_hapl[j] = 0; should be sufficient...] + } + compute_ehh(data,j,DERIVED,*nbr_snps,*nbr_chrs,tot_nbr_hapl[idx_thread],*min_nbr_hapl,*min_ehh,ehh[idx_thread]); // compute the EHH for the derived allele + ihh_vect[j + *nbr_snps] = integrate(map,ehh[idx_thread],*nbr_snps,*min_ehh); // compute the IHH for the derived allele + for (i = 0; i < *nbr_snps; i++) { + ehhs_tang[idx_thread][i] = 0.0; // Initialize the `ehhs' vector + ehhs_sabeti[idx_thread][i] = 0.0; // Initialize the `ehhs' vector + tot_nbr_hapl[idx_thread][i] = 0; // Initialize the total number of haplotypes [N.B: might be unnecessary, tot_nbr_hapl[j] = 0; should be sufficient...] + } + compute_ehhs(data,j,*nbr_snps,*nbr_chrs,tot_nbr_hapl[idx_thread],*min_nbr_hapl,*min_ehhs,ehhs_tang[idx_thread],ehhs_sabeti[idx_thread]); // compute the EHHS for both Tang et al.'s (2007) and Sabeti et al.'s (2007) definitions + ies_tang_vect[j] = integrate(map,ehhs_tang[idx_thread],*nbr_snps,*min_ehhs); // compute the IES, using Tang et al.'s (2007) definition + ies_sabeti_vect[j] = integrate(map,ehhs_sabeti[idx_thread],*nbr_snps,*min_ehhs); // compute the IES, using Sabeti et al.'s (2007) definition + } + for (i = 0; i < *nbr_chrs; i++) { // Free the memory for the `data' array + free(data[i]); + } + free(data); + for (i = 0; i < *nbr_threads; i++) { + free(ehh[i]); + free(ehhs_tang[i]); + free(ehhs_sabeti[i]); + free(tot_nbr_hapl[i]); + } + free(ehh); + free(ehhs_tang); + free(ehhs_sabeti); + free(tot_nbr_hapl); +} diff --git a/src/Makevars b/src/Makevars new file mode 100644 index 0000000..0ee3615 --- /dev/null +++ b/src/Makevars @@ -0,0 +1,2 @@ +PKG_CFLAGS = $(SHLIB_OPENMP_CFLAGS) +PKG_LIBS = $(SHLIB_OPENMP_CFLAGS) diff --git a/src/ehh_utils.c b/src/ehh_utils.c deleted file mode 100644 index 2c09bdb..0000000 --- a/src/ehh_utils.c +++ /dev/null @@ -1,205 +0,0 @@ -#include "ehh_utils.h" - -void compute_EHH(int **data, - int number_chromosomes, - int number_SNPs, - int focal, - int end, - int direction, - int allele, - double *ehh, - int *n) - -{ - int i,j,k; - int down,up; - int haplotypes; - int found; - int missing; - int *count; - int **haplotype; - - if (direction == LEFT) { - down = end; - up = focal; - } else { - down = focal; - up = end; - } - haplotype = (int **) malloc(number_chromosomes * sizeof(int *)); - count = (int *) malloc(number_chromosomes * sizeof(int)); - haplotypes = 0; - for (i = 0; i < number_chromosomes; i++) { - if (data[i][focal] == allele) { - missing = 0; - j = down; - while ((j <= up) && (!missing)) { - if(data[i][j] == 9) { - missing = 1; - } - ++j; - } - if (!missing) { - if (haplotypes == 0) { - count[haplotypes] = 1; - haplotype[haplotypes] = data[i]; - ++haplotypes; - } else { - j = found = 0; - while ((j < haplotypes) && (!found)) { - k = down; - while((k<=up) && (data[i][k] == haplotype[j][k])) { - ++k; - } - if (k > up) { - ++count[j]; - found = 1; - } - ++j; - } - if (!found) { - count[haplotypes] = 1; - haplotype[haplotypes] = data[i]; - ++haplotypes; - } - } - } - } - } - *n = 0; - *ehh = 0.0; - if (haplotypes > 0) { - for (i = 0; i < haplotypes; i++) { - *n += count[i]; - *ehh += count[i] * (count[i] - 1.0); - } - if (*n > 1) { - *ehh /= (*n * (*n - 1.0)); - } else { - *ehh = 0.0; - } - } - free(haplotype); - free(count); -} - -void compute_EHHS(int **data, - int number_chromosomes, - int number_SNPs, - int focal, - int end, - int direction, - double *ehhs, - int *n) - -{ - int i,j,k; - int down,up; - int haplotypes; - int found; - int missing; - int **haplotype; - int *count; - int allele_count[2]; - double haplotype_homozygosity; - double homozygosity; - - if (direction == LEFT) { - down = end; - up = focal; - } else { - down = focal; - up = end; - } - haplotype = (int **) malloc(number_chromosomes * sizeof(int *)); - count = (int *) malloc(number_chromosomes * sizeof(int)); - haplotypes = 0; - for (i = 0; i < number_chromosomes; i++) { - missing = 0; - j = down; - while ((j <= up) && (!missing)) { - if(data[i][j] == 9) { - missing = 1; - } - ++j; - } - if (!missing) { - if (haplotypes == 0) { - count[haplotypes] = 1; - haplotype[haplotypes] = data[i]; - ++haplotypes; - } else { - j = found = 0; - while ((j < haplotypes) && (!found)) { - k = down; - while((k<=up) && (data[i][k] == haplotype[j][k])) { - ++k; - } - if (k > up) { - ++count[j]; - found = 1; - } - ++j; - } - if (!found) { - count[haplotypes] = 1; - haplotype[haplotypes] = data[i]; - ++haplotypes; - } - } - } - } - *n = 0; - *ehhs = 0.0; - allele_count[0] = allele_count[1] = 0; - haplotype_homozygosity = 0.0; - if (haplotypes > 0) { - for (i = 0; i < haplotypes; i++) { - *n += count[i]; - haplotype_homozygosity += pow(count[i],2); - if (haplotype[i][focal] == 0) allele_count[0] += count[i]; - if (haplotype[i][focal] == 1) allele_count[1] += count[i]; - } - homozygosity = pow(allele_count[0],2) + pow(allele_count[1],2); - haplotype_homozygosity /= pow(*n,2); - homozygosity /= pow(*n,2); - *ehhs = ((*n * haplotype_homozygosity) - 1) / ((*n * homozygosity) - 1); - } - free(haplotype); - free(count); -} - -double integrate(double *x_axis, - double *y_axis, - int n, - double threshold) - -{ - int i; - double height,width; - double area = 0.0; - - for (i = 0; i < (n - 1); i++) { - if ((y_axis[i] > threshold) || (y_axis[i + 1] > threshold)) { - if ((y_axis[i] > threshold) && (y_axis[i + 1] > threshold)) { - height = y_axis[i] + y_axis[i + 1] - 2.0 * threshold; - width = x_axis[i + 1] - x_axis[i]; - area += width * height / 2; - } else { - if (y_axis[i] > threshold) { - height = y_axis[i] - threshold; - width = ((x_axis[i + 1] * y_axis[i] - x_axis[i] * y_axis[i + 1]) + threshold * (x_axis[i] - x_axis[i + 1])) / (y_axis[i] - y_axis[i + 1]) - x_axis[i]; - area += width * height / 2; - } - if (y_axis[i + 1] > threshold) { - height = y_axis[i + 1] - threshold; - width = x_axis[i + 1] - ((x_axis[i + 1] * y_axis[i] - x_axis[i] * y_axis[i + 1]) + threshold * (x_axis[i] - x_axis[i + 1]))/ (y_axis[i] - y_axis[i + 1]); - area += width * height / 2; - } - - } - } - } - return(area); -} - diff --git a/src/ehh_utils.h b/src/ehh_utils.h deleted file mode 100644 index 1e9812d..0000000 --- a/src/ehh_utils.h +++ /dev/null @@ -1,11 +0,0 @@ -#include -#include -#include - -#define LEFT 0 -#define RIGHT 1 - -double integrate(double *x_axis,double *y_axis,int n,double threshold); -void compute_EHH(int **data,int number_chromosomes,int number_SNPs,int focal,int end,int direction,int allele,double *ehh,int *n); -void compute_EHHS(int **data,int number_chromosomes,int number_SNPs,int focal,int end,int direction,double *ehhs,int *n); - diff --git a/src/hh_utils.c b/src/hh_utils.c new file mode 100644 index 0000000..9fcd8f0 --- /dev/null +++ b/src/hh_utils.c @@ -0,0 +1,429 @@ +#include "hh_utils.h" + +void compute_ehh(short int **data, + int focl_snp, + int allele, + int nbr_snps, + int nbr_chrs, + int *tot_nbr_hapl, + int min_nbr_hapl, + double min_ehh, + double *ehh) + +{ + int i,j; + int nbr_dstnct_hapl; // Number of distinct haplotypes + int *haplotype; + int *refrnce_hapl; + int *hapl_count; + + haplotype = (int *) malloc(nbr_chrs * sizeof(int)); // `haplotype' is the list of all haplotypes + refrnce_hapl = (int *) malloc(nbr_chrs * sizeof(int)); // `refrnce_hapl' is the list of referenced haplotypes + hapl_count = (int *) malloc(nbr_chrs * sizeof(int)); // `hapl_count' gives the counts of distinct haplotypes + for (i = 0; i < nbr_chrs; i++) { + if (data[i][focl_snp] == allele) tot_nbr_hapl[focl_snp] += 1; // Count the number of haplotypes at the focal SNP that contain the `allele' + } + if (tot_nbr_hapl[focl_snp] < min_nbr_hapl) { // Except if the total number of haplotypes is less than the minimum allowed, ... + ehh[focl_snp] = 0.0; // ... in which case the EHH at the focal SNP is nought, ... + } + else { + ehh[focl_snp] = 1.0; //... the EHH at the focal SNP is 1.0, by definition + init_hapl(data,focl_snp,allele,UNDEFND,nbr_chrs,haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // initialize the array of haplotypes (for the focal SNP) that contain the `allele' +#ifdef DEBUG + { + for (i = 0; i < nbr_chrs; i++) { + printf("[pos. %d] haplotype[%d] = %d\n",focl_snp,i,haplotype[i]); + } + printf("\n\toverll nbr of haplotypes = %d\n",tot_nbr_hapl[focl_snp]); + printf("\tnbr of dstnct haplotypes = %d\n",nbr_dstnct_hapl); + for (i = 0; i < nbr_dstnct_hapl; i++) { + printf("\trefrnce_hapl[%d] = %d (%d)\n",i,refrnce_hapl[i],hapl_count[i]); + } + printf("\n"); + } +#endif + for (j = (focl_snp - 1); j >= 0; j--) { // walk along the chromosome from the focal SNP to the left-hand side, ... + updt_hapl(data,j,nbr_chrs,&tot_nbr_hapl[j],haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // ... and update the list of haplotypes +#ifdef DEBUG + { + for (i = 0; i < nbr_chrs; i++) { + printf("[pos. %d] haplotype[%d] = %d\n",j,i,haplotype[i]); + } + printf("\n\toverll nbr of haplotypes = %d\n",tot_nbr_hapl[j]); + printf("\tnbr of dstnct haplotypes = %d\n",nbr_dstnct_hapl); + for (i = 0; i < nbr_dstnct_hapl; i++) { + printf("\trefrnce_hapl[%d] = %d (%d)\n",i,refrnce_hapl[i],hapl_count[i]); + } + printf("\n"); + } +#endif + ehh[j] = hapl_homzgsty(tot_nbr_hapl[j],nbr_dstnct_hapl,hapl_count); // Compute the haplotype homozygosity at the jth SNP + if (tot_nbr_hapl[j] > min_nbr_hapl) { // If the total number of haplotypes at the jth SNP is larger than the min. number allowed, ... + if (ehh[j] < min_ehh) { // ... but if the EHH is lower than the min. number allowed, ... + break; // ... then quit the loop + } + } + else { // If the total number of haplotypes at the jth SNP is lower than the min. number allowed, ... + ehh[j] = 0.0; // ... then the EHH is nought, and ... + break; // ... quit the loop + } + } + init_hapl(data,focl_snp,allele,UNDEFND,nbr_chrs,haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // initialize the array of haplotypes +#ifdef DEBUG + { + for (i = 0; i < nbr_chrs; i++) { + printf("[pos. %d] haplotype[%d] = %d\n",focl_snp,i,haplotype[i]); + } + printf("\n\toverll nbr of haplotypes = %d\n",tot_nbr_hapl[focl_snp]); + printf("\tnbr of dstnct haplotypes = %d\n",nbr_dstnct_hapl); + for (i = 0; i < nbr_dstnct_hapl; i++) { + printf("\trefrnce_hapl[%d] = %d (%d)\n",i,refrnce_hapl[i],hapl_count[i]); + } + printf("\n"); + } +#endif + for (j = (focl_snp + 1); j < nbr_snps; j++) { // walk along the chromosome from the focal SNP to the right-hand side + updt_hapl(data,j,nbr_chrs,&tot_nbr_hapl[j],haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // ... and update the list of haplotypes +#ifdef DEBUG + { + for (i = 0; i < nbr_chrs; i++) { + printf("[pos. %d] haplotype[%d] = %d\n",j,i,haplotype[i]); + } + printf("\n\toverll nbr of haplotypes = %d\n",tot_nbr_hapl[j]); + printf("\tnbr of dstnct haplotypes = %d\n",nbr_dstnct_hapl); + for (i = 0; i < nbr_dstnct_hapl; i++) { + printf("\trefrnce_hapl[%d] = %d (%d)\n",i,refrnce_hapl[i],hapl_count[i]); + } + printf("\n"); + } +#endif + ehh[j] = hapl_homzgsty(tot_nbr_hapl[j],nbr_dstnct_hapl,hapl_count); // Compute the haplotype homozygosity at the jth SNP + if (tot_nbr_hapl[j] > min_nbr_hapl) { // If the total number of haplotypes at the jth SNP is larger than the min. number allowed, ... + if (ehh[j] < min_ehh) { // ... but if the EHH is lower than the min. number allowed, ... + break; // ... then quit the loop + } + } + else { // If the total number of haplotypes at the jth SNP is lower than the min. number allowed, ... + ehh[j] = 0.0; // ... then the EHH is nought, and ... + break; // ... quit the loop + } + } + } + free(haplotype); + free(refrnce_hapl); + free(hapl_count); +} + +void compute_ehhs(short int **data, + int focl_snp, + int nbr_snps, + int nbr_chrs, + int *tot_nbr_hapl, + int min_nbr_hapl, + double min_ehhs, + double *ehhs_tang, + double *ehhs_sabeti) + +{ + int i,j; + int nbr_dstnct_hapl; // Number of distinct haplotypes + int *haplotype; + int *refrnce_hapl; + int *hapl_count; + int *hapl_snp; + + haplotype = (int *) malloc(nbr_chrs * sizeof(int)); // `haplotype' is the list of all haplotypes + refrnce_hapl = (int *) malloc(nbr_chrs * sizeof(int)); // `refrnce_hapl' is the list of referenced haplotypes + hapl_count = (int *) malloc(nbr_chrs * sizeof(int)); // `hapl_count' gives the counts of distinct haplotypes + hapl_snp = (int *) malloc(nbr_chrs * sizeof(int)); + for (i = 0; i < nbr_chrs; i++) { + if ((data[i][focl_snp] == ANCSTRL) || (data[i][focl_snp] == DERIVED)) tot_nbr_hapl[focl_snp] += 1; // Count the number of haplotypes at the focal SNP + } + if (tot_nbr_hapl[focl_snp] < min_nbr_hapl) { // Except if the total number of haplotypes is less than the minimum allowed, ... + ehhs_tang[focl_snp] = 0.0; // ... in which case the EHHS (Tang et al's 2007) at the focal SNP is nought, ... + ehhs_sabeti[focl_snp] = 0.0; // ... in which case the EHHS (Sabeti et al's 2007) at the focal SNP is nought, ... + } + else { + ehhs_tang[focl_snp] = 1.0; //... the EHHS (Tang et al's 2007) at the focal SNP is 1.0, by definition + ehhs_sabeti[focl_snp] = 1.0; //... the EHHS (Sabeti et al's 2007) at the focal SNP is 1.0, by definition + init_hapl(data,focl_snp,ANCSTRL,DERIVED,nbr_chrs,haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // initialize the array of haplotypes (for the focal SNP) + for (j = (focl_snp - 1); j >= 0; j--) { // walk along the chromosome from the focal SNP to the left-hand side, ... + updt_hapl(data,j,nbr_chrs,&tot_nbr_hapl[j],haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // ... and update the list of haplotypes + for (i = 0; i < nbr_dstnct_hapl; i++) { + hapl_snp[i] = data[ refrnce_hapl[i] ][focl_snp]; + } + ehhs_tang[j] = site_hapl_homzgsty(tot_nbr_hapl[j],nbr_dstnct_hapl,hapl_count,hapl_snp); // Compute the haplotype homozygosity at the jth SNP, following Tang et al's (2007) + ehhs_sabeti[j] = hapl_homzgsty(tot_nbr_hapl[j],nbr_dstnct_hapl,hapl_count); // Compute the standardized haplotype homozygosity at the jth SNP, following Sabeti et al's (2007) + if (tot_nbr_hapl[j] > min_nbr_hapl) { // If the total number of haplotypes at the jth SNP is larger than the min. number allowed, ... + if ((ehhs_tang[j] < min_ehhs) && (ehhs_sabeti[j] < min_ehhs)) { // ... but if the EHHS is lower than the min. number allowed, ... + ehhs_tang[j] = 0.0; // ... then the EHHS (Tang et al's 2007) is nought, and ... + ehhs_sabeti[j] = 0.0; // ... then the EHHS (Sabeti et al's 2007) is nought, and ... + break; // ... then quit the loop + } + else if (ehhs_tang[j] < min_ehhs) { + ehhs_tang[j] = 0.0; + } + else if (ehhs_sabeti[j] < min_ehhs) { + ehhs_sabeti[j] = 0.0; + } + else { + continue; + } + } + else { // If the total number of haplotypes at the jth SNP is lower than the min. number allowed, ... + ehhs_tang[j] = 0.0; // ... then the EHHS (Tang et al's 2007) is nought, and ... + ehhs_sabeti[j] = 0.0; // ... then the EHHS (Sabeti et al's 2007) is nought, and ... + break; // ... quit the loop + } + } + init_hapl(data,focl_snp,ANCSTRL,DERIVED,nbr_chrs,haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // initialize the array of haplotypes (for the focal SNP) + for (j = (focl_snp + 1); j < nbr_snps; j++) { // walk along the chromosome from the focal SNP to the right-hand side + updt_hapl(data,j,nbr_chrs,&tot_nbr_hapl[j],haplotype,&nbr_dstnct_hapl,refrnce_hapl,hapl_count); // ... and update the list of haplotypes + for (i = 0; i < nbr_dstnct_hapl; i++) { + hapl_snp[i] = data[ refrnce_hapl[i] ][focl_snp]; + } + ehhs_tang[j] = site_hapl_homzgsty(tot_nbr_hapl[j],nbr_dstnct_hapl,hapl_count,hapl_snp); // Compute the standardized haplotype homozygosity at the jth SNP + ehhs_sabeti[j] = hapl_homzgsty(tot_nbr_hapl[j],nbr_dstnct_hapl,hapl_count); // Compute the standardized haplotype homozygosity at the jth SNP, following Sabeti et al's (2007) + if (tot_nbr_hapl[j] > min_nbr_hapl) { // If the total number of haplotypes at the jth SNP is larger than the min. number allowed, ... + if ((ehhs_tang[j] < min_ehhs) && (ehhs_sabeti[j] < min_ehhs)) { // ... but if the EHHS is lower than the min. number allowed, ... + ehhs_tang[j] = 0.0; // ... then the EHHS (Tang et al's 2007) is nought, and ... + ehhs_sabeti[j] = 0.0; // ... then the EHHS (Sabeti et al's 2007) is nought, and ... + break; // ... then quit the loop + } + else if (ehhs_tang[j] < min_ehhs) { + ehhs_tang[j] = 0.0; + } + else if (ehhs_sabeti[j] < min_ehhs) { + ehhs_sabeti[j] = 0.0; + } + else { + continue; + } + } + else { // If the total number of haplotypes at the jth SNP is lower than the min. number allowed, ... + ehhs_tang[j] = 0.0; // ... then the EHHS (Tang et al's 2007) is nought, and ... + ehhs_sabeti[j] = 0.0; // ... then the EHHS (Sabeti et al's 2007) is nought, and ... + break; // ... quit the loop + } + } + } + free(haplotype); + free(refrnce_hapl); + free(hapl_count); + free(hapl_snp); +} + +void init_hapl(short int **data, + int snp, + int frst_allele, + int scnd_allele, + int nbr_chrs, + int *haplotype, + int *nbr_dstnct_hapl, + int *refrnce_hapl, + int *hapl_count) + + +{ + int i; + int frst_allele_hapl = UNDEFND; // Initialize the haplotype that contains the the `frst_allele' + int scnd_allele_hapl = UNDEFND; // Initialize the haplotype that contains the the `scnd_allele' + + *nbr_dstnct_hapl = 0; // Initialize the number of distinct haplotypes + hapl_count[ *nbr_dstnct_hapl ] = 0; // Initialize the haplotype counts + for (i = 0; i < nbr_chrs; i++) { // Loop over all chromosomes in the sample + if (data[i][snp] == frst_allele) { // If the focal SNP from the ith chromosome contains the `frst_allele', ... + if (frst_allele_hapl == UNDEFND) { // ... and if the `frst_allele_hapl' has not been defined yet, ... + refrnce_hapl[ *nbr_dstnct_hapl ] = i; // ... then, `refrnce_hapl' refers to the ith chromosome, ... + frst_allele_hapl = *nbr_dstnct_hapl; // ... and the `frst_allele_hapl' is defined, ... + hapl_count[ *nbr_dstnct_hapl ] += 1; // ... and the haplotype count is increased, ... + *nbr_dstnct_hapl += 1; // ... and the number of distinct haplotypes is incremented + hapl_count[ *nbr_dstnct_hapl ] = 0; // ... and the haplotype count for the next haplotype is initialized + } + else { + hapl_count[ frst_allele_hapl ] += 1; // ... otherwise (if the `frst_allele_hapl' has already been defined), then increment the haplotype count + } + haplotype[i] = frst_allele_hapl; // The ith haplotype is defined + } + else if (data[i][snp] == scnd_allele) { // If the focal SNP from the ith chromosome contains the `scnd_allele', ... + if (scnd_allele_hapl == UNDEFND) { // ... and if the `scnd_allele_hapl' has not been defined yet, ... + refrnce_hapl[ *nbr_dstnct_hapl ] = i; // ... then, `refrnce_hapl' refers to the ith chromosome, ... + scnd_allele_hapl = *nbr_dstnct_hapl; // ... and the `scnd_allele_hapl' is defined, ... + hapl_count[ *nbr_dstnct_hapl ] += 1; // ... and the haplotype count is increased, ... + *nbr_dstnct_hapl += 1; // ... and the number of distinct haplotypes is incremented + hapl_count[ *nbr_dstnct_hapl ] = 0; // ... and the haplotype count for the next haplotype is initialized + } + else { + hapl_count[ scnd_allele_hapl ] += 1; // ... otherwise (if the `scnd_allele_hapl' has already been defined), then increment the haplotype count + } + haplotype[i] = scnd_allele_hapl; // The ith haplotype is defined + } + else { + haplotype[i] = UNDEFND; // If the focal SNP from the ith chromosome contains neither the `frst_allele', nor the `scnd_allele', then it is undefined + } + } +} + +void updt_hapl(short int** data, + int snp, + int nbr_chrs, + int *tot_nbr_hapl, + int *haplotype, + int *nbr_dstnct_hapl, + int *refrnce_hapl, + int *hapl_count) + +{ + int i,k; + int *derived_hapl = (int *) malloc(nbr_chrs * sizeof(int)); + int *ancstrl_hapl = (int *) malloc(nbr_chrs * sizeof(int)); + + *tot_nbr_hapl = 0; // Initialize the total number of haplotypes + for (i = 0; i < nbr_chrs; i++) { + derived_hapl[i] = UNDEFND; // All derived haplotypes are set to UNDEFND + ancstrl_hapl[i] = UNDEFND; + } + for (i = 0; i < nbr_chrs; i++) { + if (haplotype[i] != UNDEFND) { // The following is only for defined haplotypes (e.g., for haplotypes that carry the reference allele) + if (data[i][snp] == MISSING) { // If the data is missing at the SNP considered for the ith haplotype, ... + if (refrnce_hapl[ haplotype[i] ] == i) { // ... and if the ith haplotype is a referenced copy of itself, ... + for (k = 0; k < nbr_chrs; k++) { // ... then loop over all chromosomes, ... + if ((i != k) && (haplotype[k] == haplotype[i])) { // ... to look for another copy (k) of the referenced haplotype copy + refrnce_hapl[ haplotype[i] ] = k; + hapl_count[ haplotype[i] ] -= 1; // ... and decrease the haplotype count for haplotype[i] + break; + } + } + if (k == nbr_chrs) { // If no copy of the referenced haplotype is found (which means that the referenced haploype no longer exists), ... + for (k = 0; k < nbr_chrs; k++) { // ... then loop over all chromosomes, ... + if (haplotype[k] == (*nbr_dstnct_hapl - 1)) { // ... to replace the haplotype reference which no longer exists, with the last element of the list of reference haplotypes + haplotype[k] = haplotype[i]; + } + } + + if (ancstrl_hapl[ (*nbr_dstnct_hapl - 1) ] != UNDEFND) { // If the haplotype reference that is being erased had a derived haplotype, ... + derived_hapl[ ancstrl_hapl[ (*nbr_dstnct_hapl - 1) ] ] = haplotype[i]; // ... then re-assign the derived haplotype, ... + ancstrl_hapl[ haplotype[i] ] = ancstrl_hapl[ (*nbr_dstnct_hapl - 1) ]; // ... and the ancestral haplotype + } + + refrnce_hapl[ haplotype[i] ] = refrnce_hapl[ *nbr_dstnct_hapl - 1 ]; // Replace the (current) referenced haplotype with the last one in the list of reference haplotypes, ... + hapl_count[ haplotype[i] ] = hapl_count[ *nbr_dstnct_hapl - 1 ]; // ... and take the corresponding haplotype count + *nbr_dstnct_hapl -= 1; // ... and decrease the number of distinct haplotypes by one + } + haplotype[i] = UNDEFND; // ... then (if the data is missing at the SNP considered) the ith haplotype is undefined +// derived_hapl[ haplotype[i] ] = UNDEFND; // ... as well as the haplotype that derives from the ith haplotype + } + else { // ... otherwise (if the ith haplotype is NOT a referenced copy of itself), ... + hapl_count[ haplotype[i] ] -= 1; // ... then decrease the haplotype count for haplotype[i] + haplotype[i] = UNDEFND; // ... and set the ith haplotype to the undefined state +// derived_hapl[ haplotype[i] ] = UNDEFND; // ... as well as the haplotype that derives from the ith haplotype + } + } + else if (data[i][snp] != data[ refrnce_hapl[ haplotype[i] ] ][snp]) { // If (at the position considered) the ith chromosome carries a new allele that differs from the referenced haplotype + if (derived_hapl[ haplotype[i] ] != UNDEFND) { // ... and if a derived haplotype already exists, ... + hapl_count[ haplotype[i] ] -= 1; // ... then decrease the haplotype count for the `old' haplotype[i], ... + haplotype[i] = derived_hapl[ haplotype[i] ]; // ... and the ith haplotype is set to its derived haplotype, ... + hapl_count[ haplotype[i] ] += 1; // ... and increase the haplotype count for the `new' haplotype[i] + } + else { // ... otherwise (if a derived haplotype does not exist yet), ... + refrnce_hapl[ *nbr_dstnct_hapl ] = i; // ... then `refrnce_hapl' refers to the ith chromosome, ... + derived_hapl[ haplotype[i] ] = *nbr_dstnct_hapl; // ... define the derived haplotype, ... + ancstrl_hapl[ *nbr_dstnct_hapl ] = haplotype[i]; // ... and define the ancestral haplotype + hapl_count[ haplotype[i] ] -= 1; // ... then decrease the haplotype count for the `old' haplotype[i] + haplotype[i] = derived_hapl[ haplotype[i] ]; // ... the ith haplotype is set to its derived haplotype, ... + hapl_count[ haplotype[i] ] = 1; // ... and set the haplotype count for the `new' haplotype[i] to one, ... + *nbr_dstnct_hapl += 1; // ... and the number of distinct haplotypes is incremented + } + *tot_nbr_hapl += 1; // Increment the total number of haplotypes (for newly defined haplotypes) + } + else { + *tot_nbr_hapl += 1; // Increment the total number of haplotypes (for haplotypes that already exist) + } + } + } + free(derived_hapl); + free(ancstrl_hapl); +} + +double hapl_homzgsty(int tot_nbr_hapl, + int nbr_dstnct_hapl, + int *hapl_count) + +{ + int i; + double homzgsty; + + homzgsty = 0.0; // Initialize the homozygosity + for (i = 0; i < nbr_dstnct_hapl; i++) { // Loop over all distinct haplotypes, ... + homzgsty += (double) hapl_count[i] * (hapl_count[i] - 1.0); // ... to compute the homozygosity + } + if (tot_nbr_hapl > 1) { // If the total number of haplotypes is larger than 1, ... + homzgsty /= (double) (tot_nbr_hapl * (tot_nbr_hapl - 1.0)); // ... then finalize the computation of homozygosity, ... + } + else { + homzgsty = 0.0; // ... otherwise, homozygosity is nought + } + return(homzgsty); +} + +double site_hapl_homzgsty(int tot_nbr_hapl, + int nbr_dstnct_hapl, + int *hapl_count, + int *hapl_snp) + +{ + int i; + int allele_count[2]; + double hapl_homzgsty,homzgsty; + + hapl_homzgsty = 0.0; // Initialize the haplotype homozygosity + allele_count[ANCSTRL] = allele_count[DERIVED] = 0; // Initialize the allele counts + if (nbr_dstnct_hapl > 0) { + for (i = 0; i < nbr_dstnct_hapl; i++) { // Loop over all distinct haplotypes, ... + hapl_homzgsty += pow(hapl_count[i],2.0); // ... to compute the haplotype homozygosity, ... + if (hapl_snp[i] == ANCSTRL) allele_count[ANCSTRL] += hapl_count[i]; // ... and the allele counts for each of the ANCESTRL and DERIVED SNPs + if (hapl_snp[i] == DERIVED) allele_count[DERIVED] += hapl_count[i]; + } + hapl_homzgsty /= pow(tot_nbr_hapl,2.0); // Finalize the computation of haplotype homozygosity + homzgsty = pow(allele_count[ANCSTRL],2.0) + pow(allele_count[DERIVED],2.0); + homzgsty /= pow(tot_nbr_hapl,2.0); + return ((((double) tot_nbr_hapl * hapl_homzgsty) - 1.0) / (((double) tot_nbr_hapl * homzgsty) - 1.0)); + } + else { + return (0.0); + } +} + +double integrate(double *x_axis, + double *y_axis, + int n, + double threshold) + +{ + int i; + double height,width; + double area = 0.0; + + for (i = 0; i < (n - 1); i++) { + if ((y_axis[i] > threshold) || (y_axis[i + 1] > threshold)) { + if ((y_axis[i] > threshold) && (y_axis[i + 1] > threshold)) { + height = y_axis[i] + y_axis[i + 1] - 2.0 * threshold; + width = x_axis[i + 1] - x_axis[i]; + area += width * height / 2; + } + else { + if (y_axis[i] > threshold) { + height = y_axis[i] - threshold; + width = ((x_axis[i + 1] * y_axis[i] - x_axis[i] * y_axis[i + 1]) + threshold * (x_axis[i] - x_axis[i + 1])) / (y_axis[i] - y_axis[i + 1]) - x_axis[i]; + area += width * height / 2; + } + if (y_axis[i + 1] > threshold) { + height = y_axis[i + 1] - threshold; + width = x_axis[i + 1] - ((x_axis[i + 1] * y_axis[i] - x_axis[i] * y_axis[i + 1]) + threshold * (x_axis[i] - x_axis[i + 1])) / (y_axis[i] - y_axis[i + 1]); + area += width * height / 2; + } + } + } + } + return (area); +} diff --git a/src/hh_utils.h b/src/hh_utils.h new file mode 100644 index 0000000..4a27133 --- /dev/null +++ b/src/hh_utils.h @@ -0,0 +1,19 @@ +#include +#include +#include + +//#define DEBUG + +#define ANCSTRL 0 +#define DERIVED 1 +#define MISSING 9 +#define UNDEFND -1 + +void compute_ehh(short int **data,int focl_snp, int allele,int nbr_snps,int nbr_chrs,int *tot_nbr_hapl,int min_nbr_hapl,double min_ehh,double *ehh); +void compute_ehhs(short int **data,int focl_snp,int nbr_snps,int nbr_chrs,int *tot_nbr_hapl,int min_nbr_hapl,double min_ehhs,double *ehhs_tang,double *ehhs_sabeti); +void init_hapl(short int **data,int snp,int frst_allele,int scnd_allele,int nbr_chrs,int *haplotype,int *nbr_dstnct_hapl,int *refrnce_hapl,int *hapl_count); +void updt_hapl(short int **data,int snp,int nbr_chrs,int *tot_nbr_hapl,int *haplotype,int *nbr_dstnct_hapl,int *refrnce_hapl,int *hapl_count); +double hapl_homzgsty(int tot_nbr_hapl,int nbr_dstnct_hapl,int *hapl_count); +double site_hapl_homzgsty(int tot_nbr_hapl,int nbr_dstnct_hapl,int *hapl_count,int *hapl_snp); +//double site_hapl_homzgsty_sabeti(int tot_nbr_hapl,int nbr_dstnct_hapl,int *hapl_count,int *hapl_snp); +double integrate(double *x_axis, double *y_axis, int n, double threshold); diff --git a/src/r_ehh.c b/src/r_ehh.c deleted file mode 100644 index 356556a..0000000 --- a/src/r_ehh.c +++ /dev/null @@ -1,96 +0,0 @@ -#include -#include -#include -#include -#include "ehh_utils.h" - -void r_ehh(int *Rdata, - int *number_SNPs, - int *number_chromosomes, - int *focal_SNP, - double *map, - int *number_haplotypes, - double *EHH, - double *IHH, - int *min_number_haplotypes, - double *min_EHH) - -{ - int i,j; - int allele; - int n; - int **data; - double ehh; - double *tmp; - - *focal_SNP -= 1; - data = (int **) malloc(*number_chromosomes * sizeof(int *)); - for (i = 0; i < *number_chromosomes; i++) { - data[i] = (int *) malloc(*number_SNPs * sizeof(int)); - } - for (i = 0; i < *number_chromosomes; i++) { - for (j = 0; j < *number_SNPs; j++) { - if (Rdata[(j * *number_chromosomes) + i] == 0) data[i][j] = 9; - if (Rdata[(j * *number_chromosomes) + i] == 1) data[i][j] = 0; - if (Rdata[(j * *number_chromosomes) + i] == 2) data[i][j] = 1; - } - } - for (j = 0; j < *number_SNPs; j++) { - for (allele = 0; allele < 2; allele++) { - EHH[(allele * *number_SNPs) + j] = 0.0; - number_haplotypes[(allele * *number_SNPs) + j] = 0; - } - } - EHH[*focal_SNP] = EHH[*number_SNPs + *focal_SNP] = 1.0; - number_haplotypes[*focal_SNP] = number_haplotypes[*number_SNPs + *focal_SNP] = 0; - for (i = 0; i < *number_chromosomes; i++) { - if (data[i][*focal_SNP] == 0) number_haplotypes[*focal_SNP] += 1; - if (data[i][*focal_SNP] == 1) number_haplotypes[*number_SNPs + *focal_SNP] += 1; - } - for (allele = 0; allele < 2; allele++) { - if (number_haplotypes[(allele * *number_SNPs) + *focal_SNP] < *min_number_haplotypes) { - EHH[(allele * *number_SNPs) + *focal_SNP] = 0.0; - } else { - for (j = (*focal_SNP - 1); j >= 0; j--) { - compute_EHH(data,*number_chromosomes,*number_SNPs,*focal_SNP,j,LEFT,allele,&ehh,&n); - if (n > *min_number_haplotypes) { - EHH[(allele * *number_SNPs) + j] = ehh; - number_haplotypes[(allele * *number_SNPs) + j] = n; - if(ehh < *min_EHH){ - break; - } - } else { - break; - } - - - } - for (j = (*focal_SNP + 1); j < *number_SNPs; j++) { - compute_EHH(data,*number_chromosomes,*number_SNPs,*focal_SNP,j,RIGHT,allele,&ehh,&n); - if (n > *min_number_haplotypes) { - EHH[(allele * *number_SNPs) + j] = ehh; - number_haplotypes[(allele * *number_SNPs) + j] = n; - if(ehh < *min_EHH){ - break; - } - } else { - break; - } - - - } - } - } - tmp = (double *) malloc(*number_SNPs * sizeof(double)); - for (allele = 0; allele < 2; allele++) { - for (j = 0; j < *number_SNPs; j++) { - tmp[j] = EHH[(allele * *number_SNPs) + j]; - } - IHH[allele] = integrate(map,tmp,*number_SNPs,*min_EHH); - } - for (i = 0; i < *number_chromosomes; i++) { - free(data[i]); - } - free(data); - free(tmp); -} diff --git a/src/r_ehhs.c b/src/r_ehhs.c deleted file mode 100644 index 1d8b277..0000000 --- a/src/r_ehhs.c +++ /dev/null @@ -1,82 +0,0 @@ -#include -#include -#include -#include -#include "ehh_utils.h" - -void r_ehhs(int *Rdata, - int *number_SNPs, - int *number_chromosomes, - int *focal_SNP, - double *map, - int *number_haplotypes, - double *EHHS, - double *IES, - int *min_number_haplotypes, - double *min_EHH) - -{ - int i,j; - int n; - int **data; - double ehhs; - - *focal_SNP -= 1; - data = (int **) malloc(*number_chromosomes * sizeof(int *)); - for (i = 0; i < *number_chromosomes; i++) { - data[i] = (int *) malloc(*number_SNPs * sizeof(int)); - } - for (i = 0; i < *number_chromosomes; i++) { - for (j = 0; j < *number_SNPs; j++) { - if (Rdata[(j * *number_chromosomes) + i] == 0) data[i][j] = 9; - if (Rdata[(j * *number_chromosomes) + i] == 1) data[i][j] = 0; - if (Rdata[(j * *number_chromosomes) + i] == 2) data[i][j] = 1; - } - } - for (j = 0; j < *number_SNPs; j++) { - EHHS[j] = 0.0; - number_haplotypes[j] = 0; - } - EHHS[*focal_SNP] = 1.0; - number_haplotypes[*focal_SNP] = 0; - for (i = 0; i < *number_chromosomes; i++) { - if (data[i][*focal_SNP] == 0) number_haplotypes[*focal_SNP] += 1; - if (data[i][*focal_SNP] == 1) number_haplotypes[*focal_SNP] += 1; - } - if (number_haplotypes[*focal_SNP] < *min_number_haplotypes) { - EHHS[*focal_SNP] = 0.0; - } else { - for (j = (*focal_SNP - 1); j >= 0; j--) { - compute_EHHS(data,*number_chromosomes,*number_SNPs,*focal_SNP,j,LEFT,&ehhs,&n); - if (n > *min_number_haplotypes) { - EHHS[j] = ehhs; - number_haplotypes[j] = n; - if(ehhs < *min_EHH){ - break; - } - } else { - break; - } - - - } - for (j = (*focal_SNP + 1); j < *number_SNPs; j++) { - compute_EHHS(data,*number_chromosomes,*number_SNPs,*focal_SNP,j,RIGHT,&ehhs,&n); - if (n > *min_number_haplotypes) { - EHHS[j] = ehhs; - number_haplotypes[j] = n; - if(ehhs < *min_EHH){ - break; - } - } else { - break; - } - - } - } - *IES = integrate(map,EHHS,*number_SNPs,*min_EHH); - for (i = 0; i < *number_chromosomes; i++) { - free(data[i]); - } - free(data); -} diff --git a/src/r_scan_hh.c b/src/r_scan_hh.c deleted file mode 100644 index 1332317..0000000 --- a/src/r_scan_hh.c +++ /dev/null @@ -1,156 +0,0 @@ -#include -#include -#include -#include -#include "ehh_utils.h" - -void r_scan_hh(int *Rdata, - int *number_SNPs, - int *number_chromosomes, - double *map, - double *IHH, - double *IES, - int *min_number_haplotypes, - double *min_EHH, - double *min_EHHS -) - -{ - int i,j; - int focal_SNP; - int allele; - int n; - int **data; - int **number_haplotypes; - double ehh,ehhs; - double *tmp; - double **EHH; - double *EHHS; - - data = (int **) malloc(*number_chromosomes * sizeof(int *)); - for (i = 0; i < *number_chromosomes; i++) { - data[i] = (int *) malloc(*number_SNPs * sizeof(int)); - } - for (i = 0; i < *number_chromosomes; i++) { - for (j = 0; j < *number_SNPs; j++) { - if (Rdata[(j * *number_chromosomes) + i] == 0) data[i][j] = 9; - if (Rdata[(j * *number_chromosomes) + i] == 1) data[i][j] = 0; - if (Rdata[(j * *number_chromosomes) + i] == 2) data[i][j] = 1; - } - } - EHHS = (double *) malloc(*number_SNPs * sizeof(double)); - number_haplotypes = (int **) malloc(*number_SNPs * sizeof(int *)); - EHH = (double **) malloc(*number_SNPs * sizeof(double *)); - for (j = 0; j < *number_SNPs; j++) { - number_haplotypes[j] = (int *) malloc(2 * sizeof(int)); - EHH[j] = (double *) malloc(2 * sizeof(double)); - } - tmp = (double *) malloc(*number_SNPs * sizeof(double)); - for (focal_SNP = 0; focal_SNP < *number_SNPs; focal_SNP++) { - for (j = 0; j < *number_SNPs; j++) { - for (allele = 0; allele < 2; allele++) { - EHH[j][allele] = 0.0; - number_haplotypes[j][allele] = 0; - } - } - EHH[focal_SNP][0] = EHH[focal_SNP][1] = 1.0; -// number_haplotypes[focal_SNP][0] = number_haplotypes[focal_SNP][1] = 0; - for (i = 0; i < *number_chromosomes; i++) { - if (data[i][focal_SNP] == 0) number_haplotypes[focal_SNP][0] += 1; - if (data[i][focal_SNP] == 1) number_haplotypes[focal_SNP][1] += 1; - } - for (allele = 0; allele < 2; allele++) { - if (number_haplotypes[focal_SNP][allele] < *min_number_haplotypes) { - EHH[focal_SNP][allele] = 0.0; - } else { - for (j = (focal_SNP - 1); j >= 0; j--) { - compute_EHH(data,*number_chromosomes,*number_SNPs,focal_SNP,j,LEFT,allele,&ehh,&n); - if (n > *min_number_haplotypes) { - EHH[j][allele] = ehh; - number_haplotypes[j][allele] = n; - if(ehh < *min_EHH){ - break; - } - } else { - break; - } - - } - for (j = (focal_SNP + 1); j < *number_SNPs; j++) { - compute_EHH(data,*number_chromosomes,*number_SNPs,focal_SNP,j,RIGHT,allele,&ehh,&n); - if (n > *min_number_haplotypes) { - EHH[j][allele] = ehh; - number_haplotypes[j][allele] = n; - if(ehh < *min_EHH){ - break; - } - } else { - break; - } - - } - } - } - for (allele = 0; allele < 2; allele++) { - for (j = 0; j < *number_SNPs; j++) { - tmp[j] = EHH[j][allele]; - } - IHH[(allele * *number_SNPs) + focal_SNP] = integrate(map,tmp,*number_SNPs,*min_EHH); - } - for (j = 0; j < *number_SNPs; j++) { - EHHS[j] = 0.0; - number_haplotypes[j][0] = 0; - } - EHHS[focal_SNP] = 1.0; - number_haplotypes[focal_SNP][0] = 0; - for (i = 0; i < *number_chromosomes; i++) { - if (data[i][focal_SNP] == 0) number_haplotypes[focal_SNP][0] += 1; - if (data[i][focal_SNP] == 1) number_haplotypes[focal_SNP][0] += 1; - } - if (number_haplotypes[focal_SNP][0] < *min_number_haplotypes) { - EHHS[focal_SNP] = 0.0; - } else { - for (j = (focal_SNP - 1); j >= 0; j--) { - compute_EHHS(data,*number_chromosomes,*number_SNPs,focal_SNP,j,LEFT,&ehhs,&n); - if (n > *min_number_haplotypes) { - EHHS[j] = ehhs; - number_haplotypes[j][0] = n; - if(ehhs < *min_EHHS){ - break; - } - } else { - break; - } - - - } - for (j = (focal_SNP + 1); j < *number_SNPs; j++) { - compute_EHHS(data,*number_chromosomes,*number_SNPs,focal_SNP,j,RIGHT,&ehhs,&n); - if (n > *min_number_haplotypes) { - EHHS[j] = ehhs; - number_haplotypes[j][0] = n; - if(ehhs < *min_EHHS){ - break; - } - } else { - break; - } - - } - } - IES[focal_SNP] = integrate(map,EHHS,*number_SNPs,*min_EHHS); -// Rprintf("SNP = %d \tout of\t %d SNPs\n",focal_SNP+1,*number_SNPs); - } - for (i = 0; i < *number_chromosomes; i++) { - free(data[i]); - } - free(data); - free(EHHS); - for (j = 0; j < *number_SNPs; j++) { - free(number_haplotypes[j]); - free(EHH[j]); - } - free(number_haplotypes); - free(EHH); - free(tmp); -} diff --git a/vignettes/genetics.csl b/vignettes/genetics.csl new file mode 100644 index 0000000..173307c --- /dev/null +++ b/vignettes/genetics.csl @@ -0,0 +1,147 @@ + + diff --git a/vignettes/rehh.Rmd b/vignettes/rehh.Rmd new file mode 100644 index 0000000..ccc9a25 --- /dev/null +++ b/vignettes/rehh.Rmd @@ -0,0 +1,632 @@ + %\VignetteEngine{knitr::knitr} + %\VignetteIndexEntry{How to use rehh} + %\usepackage[utf8]{inputenc} +--- +title: "Vignette for the package *rehh* (version 2+)" +author: "Mathieu Gautier, Alexander Klassmann and Renaud Vitalis" +date: "29/07/2016" +output: + pdf_document: + fig_caption: yes + number_sections: yes + toc: yes + html_document: + toc: yes +csl: genetics.csl +bibliography: vignette.bib +--- + +```{r setup, include=FALSE} +knitr::opts_chunk$set(comment=">") +``` + +\newpage +This vignette is aimed at presenting additional information on the R package \emph{rehh} by describing how to use it to perform whole genome scan for footprints of selection using statistics related to the Extended Haplotype Homozygosity (EHH) [@Sabeti2002]. Importantly, the current implementation of tests assumes markers are bi-allelic. + +The \emph{rehh} package is currently available for most platforms (Linux, MS Windows and MacOSX) from the CRAN repository (\url{http://cran.r-project.org/}) and may be installed using standard procedure. Once the package has been successfully installed on your system, it can be loaded using the following command: +```{r message=FALSE} +library(rehh) +``` + +#Input Files +\label{make.example.files} + +The package \emph{rehh} basically requires as input: + +1. haplotype data file(s) (in three possible format) for each population of interest (see \ref{hap.file}) +2. a SNP information file (see \ref{map.file}) + +**Important Note: For a given chromosome, SNPs are assumed to be ordered in the same way in both the haplotype file (columns) and the SNP information file.** + +For illustration purposes, example files that originate from a previously published study on the Creole cattle breed from Guadeloupe (CGU) [@Gautier2011] are provided in the package and can be copied in the working directory with the following command: +```{r results='hide'} +make.example.files() +``` + +In the following examples, the command \texttt{make.example.file()} is assumed to have been run (see above) so that example files are in the working directory. + +##Haplotype data file +\label{hap.file} + +Three haplotype input file formats are supported: + +1. a standard haplotype format. Each line represents a haplotype (the first element being an haplotype identifier) with SNP genotype in columns as in the example file \texttt{bta12\_cgu.hap} created when running the function \texttt{make.example.files()} and that consists of 280 haplotypes (identifier 1 to 280) of 1424 SNPs each. See \ref{LoadDataEx1} for a detailed example. +2. A (transposed) format with haplotype in columns and SNPs in row as in the example file \texttt{bta12\_cgu.thap} created when running the function \texttt{make.example.files()}. Note that this format is similar to the one produced by the phasing program \emph{SHAPEIT2} [@OConnell2014]. See \ref{LoadDataEx2} for a detailed example. +3. the output file format from the phasing program \emph{fastPHASE} [@Scheet2006] as in the \texttt{bta12\_hapguess\_switch.out} example file created when running the function \texttt{make.example.files()}. Note that haplotypes might originate from several different populations (i.e., if the -u \emph{fastPHASE} option was used). See \ref{LoadDataEx3} for a detailed example. + +By default alleles are assumed to be coded as 0 (missing data), 1 (ancestral allele) or 2 (derived allele). Recoding of the alleles in this format, according to the SNP information data file (see \ref{map.file}) can be performed with the \texttt{recode.allele} option of the function \texttt{data2haplohh()} (see \ref{LoadData}). + +##SNP information data file +\label{map.file} + +This data file should contain SNP information as in the \texttt{map.inp} example file created when running the function \texttt{make.example.files()}. Each line contains five columns corresponding to: + +1. the SNP name +2. the SNP chromosome (or scaffold) of origin +3. the SNP position on the chromosome (or scaffold). Note that it is up to the user to choose either physical or genetic map positions (if available). +4. the SNP ancestral allele (as coded in the haplotype input file) +5. the SNP derived alleles (as coded in the haplotype input file) + +The fourth and fifth columns (allele coding) should be filled in but the corresponding information is only used when activating the \texttt{recode.allele} option of the function \texttt{data2haplohh()} (see \ref{LoadData}). In that case, for each SNP, the allele specified in the fourth (respectively fifth) column will be recoded as 1 (respectively 2), any other allele name will be recoded as 0 (i.e., missing data). More importantly, it should be noticed that the ancestral or derived allele information associated to this coding are only relevant for within population tests (based on \emph{iHS}). In other words, if one is only interested in across-population tests (based on \emph{Rsb} or \emph{xpEHH}), assignment of the two SNP alleles in the fourth and fifth column may be performed randomly. + +As an illustration, the following R command displays the first five row of the \texttt{map.inp} example file created when running the function \texttt{make.example.files()}: + +```{r} +head(read.table("map.inp")) +``` + + +##Loading data files +\label{LoadData} +The \texttt{data2haplohh()} function allows to convert data file into an R object of class \texttt{haplohh} subsequently used by the functions of the \emph{rehh} package. The following main options are available to recode alleles or select SNPs (based on Minor Allele Frequency or percentage of missing data) and haplotypes (based on percentage of missing data): + +1. **Allele recoding option**: This option is activated with \texttt{recode.allele=TRUE} and allows to recode haplotype according to the ancestral and derived allele definition available in the SNP information file (fourth and fifth columns) as: 0 (missing data), 1 (ancestral allele) or 2 (derived allele). +2. **Discard haplotypes with a high amount of missing data**. If haplotypes contain missing data (which is generally not the case since most phasing programs allow imputing missing genotypes), it is possible to discard those with less \texttt{min\_perc\_geno.hap} \% of the SNPs genotyped. By default \texttt{min\_perc\_geno.hap=100} meaning that only completely phased haplotypes are retained. +3. **Discard SNPs with a high amount of missing data**. It is possible to discard SNPs genotyped on less than \texttt{min\_perc\_geno.snp} \% of the haplotypes. By default \texttt{min\_perc\_geno.snp=100} meaning that only fully genotyped SNPs are retained. +4. **Discard SNPs with a low Minor Allele Frequency**. It is possible to discard SNPs with a MAF below \texttt{min\_maf}. This is generally not recommended and by default \texttt{min\_maf=0} meaning that all SNPs are retained.\footnote{The arguments \texttt{min\_perc\_geno.hap}, \texttt{min\_perc\_geno.snp} and \texttt{min\_maf} are evaluated in this order.} + +More details about the different arguments of the function are available in the documentation accessible using the command: +```{r} +?data2haplohh +``` + +In the following we detail three different examples based on the example data files provided with the package (see \ref{make.example.files}). + +###Example 1: reading haplotype file in standard format +\label{LoadDataEx1} +In this example, the example haplotype input file \texttt{bta12\_cgu.hap} (standard format) and SNP information input files \texttt{map.inp} are converted into an \texttt{haplohh} object named \texttt{hap}. Because the map file contains information for SNPs mapping to other chromosomes than the one of interest (BTA12), we use the option \texttt{chr.name=12}. Allele recoding is activated (\texttt{recode.allele=TRUE}) to allow recoding alleles in the \emph{rehh} format (0,1 or 2). +```{r } +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE,chr.name=12) +``` + +If no value is specified for \texttt{chr.name} argument and more than one chromosome is detected in the map file, the function asks interactively which chromosome to choose: + +```{r eval=FALSE} +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE) +``` +```{r echo=FALSE} +cat("More than one chromosome name in Map file: map.inp\nWhich chromosome should be considered among:\n1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29\n1:") +``` +```{r eval=FALSE} +12 +``` +```{r echo=FALSE} +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp",recode.allele=TRUE,chr.name=12) +``` + +Finally, as an example of error message, the following message is prompted if the number of SNPs in the chromosome (for instance when a wrong chromosome is declared) does not correspond to the one in the haplotype file: + +```{r error=TRUE} +hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp", + recode.allele=TRUE,chr.name=18) +``` + +###Example 2: reading haplotype file in transposed format (\emph{SHAPIT2}--like) +\label{LoadDataEx2} + +In this example, the example haplotype input file \texttt{bta12\_cgu.thap} (transposed format) and SNP information input files \texttt{map.inp} are converted into an \texttt{haplohh} object named \texttt{hap}. Setting \texttt{haplotype.in.columns=TRUE} informs the function that the haplotype file is in transposed format: +```{r} +hap<-data2haplohh(hap_file="bta12_cgu.thap",map_file="map.inp",haplotype.in.columns=TRUE, + recode.allele=TRUE,chr.name=12) +``` + +###Example 3: reading haplotype file in \emph{fastPHASE} output format +\label{LoadDataEx3} +In this example, the example \emph{fastPHASE} output file \texttt{bta12\_hapguess\_switch.out} and SNP information input files \texttt{map.inp} are +converted into a \texttt{haplohh} object named \texttt{haplo}. As explained above we use the option \texttt{chr.name=12}. +Because, haplotypes originate from several populations (the -u \emph{fastPHASE} option was used), we specify the population of interest +(in our example the 280 haplotypes from the CGU population, see above) using the option \texttt{popsel=7} +(7 corresponding to the code of CGU in the example \emph{fastPHASE} input files). + +```{r} +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", + recode.allele=TRUE,popsel=7,chr.name=12) +``` + +If no value is specified for the \texttt{popsel} argument and more than one population is detected in the \emph{fastPHASE} output file, the function asks interactively which population to chose: + +```{r eval=FALSE} +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp", + recode.allele=TRUE,chr.name=12) +``` +```{r echo=FALSE} +cat("Map file seems OK: 1424 SNPs declared for chromosome 12\nLooks like a FastPHASE haplotype file\nHaplotypes originate from 8 different populations in the fastPhase output file\nChosen pop. is not in the list of pop. number: 1 2 3 4 5 6 7 8\nWhich population should be considered among: 1 2 3 4 5 6 7 8\n1: +") +``` +```{r eval=FALSE} +7 +``` +```{r echo=FALSE} +hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp",recode.allele=TRUE,popsel=7,chr.name=12) +``` + +#Computing \emph{EHH}-based statistics for individual markers with the \texttt{calc\_ehh()}, \texttt{calc\_ehhs()} and \texttt{scan\_hh()} functions +##Definition and Computation + +###The (allele-specific) Extended Haplotype Homozygosity (\emph{EHH}) +\label{EHH} +For a given core allele (i.e., the ancestral or derived allele) at a focal SNP, the (allele--specific) extended haplotype homozygosity (\emph{EHH}) is defined as the probability that two randomly chosen chromosomes (carrying the core allele considered) are identical by descent (as assayed by homozygosity at all SNPs) over a given surrounding chromosome region [@Sabeti2002]. The \emph{EHH} thus aims at measuring to which extent an extended haplotype is transmitted without recombination. In practice, the \emph{EHH} ($\mathrm{EHH}_{s,t}$) of a tested core allele $a_s$ ($a_s=1$ or $a_s=2$) for a focal SNP $s$ over the chromosome interval extending to SNP $t$ is computed as: +\begin{equation} +\label{ehh.def} +\mathrm{EHH}_{s,t}=\frac{1}{n_{a_s}(n_{a_s}-1)}\sum\limits_{k=1}^{K_{a_s,t}}n_k(n_k-1) +\end{equation} +where $n_{a_s}$ represents the number of haplotype carrying the core allele $a_s$, $K_{a_s,t}$ represents the number of different extended haplotypes (from SNP $s$ to SNP $t$) carrying $a_s$ and $n_k$ is the number of the extended haplotype $k$ (i.e., $n_{a_s}=\sum\limits_{k=1}^{K_{a_s,t}}n_k$). + +###The integrated (allele-specific) \emph{EHH} (\emph{iHH}) +\label{iHH} +By definition, irrespective of the allele considered, \emph{EHH} starts at 1, and decays monotonically to 0 with increasing distance from the focal SNP. For a given core allele, the integrated \emph{EHH} (\emph{iHH}) is defined as the area under the \emph{EHH} curve with respect to map position [@Voight2006]\footnote{In their seminal paper, Voight et al. considered genetic distances and apply a penalty (proportional to physical distances) for successive SNPs separated by more than 20 kb. In addition, they did not compute \emph{iHH} if any physical distance between a pair of neighboring SNPs was above 200 kb. We did not implement such an approach in \emph{rehh} although this might easily be done (providing relevant information is available for the genome of interest) by modifying the positions of the markers in SNP information input file.}. In \emph{rehh}, \emph{iHH} is computed using the trapezoid method. In practice, the integral might only be computed for the regions of the curve above an arbitrarily small \emph{EHH} value (e.g., \emph{EHH}>0.05). + +###The site-specific Extended Haplotype Homozygosity (\emph{EHHS}) +\label{EHHS} +For a given core SNP, the (site--specific) extended haplotype homozygosity (\emph{EHHS}) is defined as the probability that two randomly chosen chromosomes are identical by descent (as assayed by homozygosity at all SNPs) over a given surrounding chromosome region. \emph{EHHS} might roughly be viewed as linear combination of the \emph{EHH}'s for the two alternative alleles with weights function of the corresponding allele frequencies. Two different \emph{EHHS} estimators further denoted as $\mathrm{EHHS}^{\text{Sab}}$ [@Sabeti2007] and $\mathrm{EHHS}^{\text{Tang}}$ [@Tang2007] have been proposed. For a focal SNP $s$ over a chromosome interval extending to SNP $t$, these are computed as (following the same notation as above): +\begin{equation} +\label{ehhssab.def} +\mathrm{EHHS}^{\text{Sab}}_{s,t}=\frac{1}{n_s(n_s-1)}\sum\limits_{a_s=1}^{a_s=2}\left(\sum\limits_{k=1}^{K_{a_s,t}}n_k(n_k-1)\right) +\end{equation} +where $n_s=\sum\limits_{a_s=1}^{a_s=2}n_{a_s}$ and +\begin{equation} +\label{ehhstang.def} +\mathrm{EHHS}^{\text{Tang}}_{s,t}=\frac{1-h_{hap}^{(s,t)}}{1-h_{all}^{(s)}} +\end{equation} +where: + +1. $h_{all}^{(s)}=\frac{n_s}{n_s-1}\left(1-\frac{1}{n_s^2}\sum\limits_{a_s=1}^{a_s=2}n_{a_s}^2 \right )$ is an estimator of the focal SNP heterozygosity +2. $h_{hap}^{(s,t)}=\frac{n_s}{n_s-1}\left(1-\frac{1}{n_s^2}\sum\limits_{a_s=1}^{a_s=2}\left(\sum\limits_{k=1}^{K_{a_s,t}}n_k^2 \right )\right)$ is an estimator of haplotype heterozygosity across the chromosome region extending from SNP $s$ to SNP $t$. + +###The integrated \emph{EHHS} (\emph{iES}) +\label{iES} +As for the \emph{EHH} (see \ref{iHH}), \emph{EHHS} starts at 1 and decays monotonically to 0 with increasing distance from the focal SNP. For a given focal SNP, and in a similar fashion as the \emph{iHH}, \emph{iES} is defined as the integrated \emph{EHHS} [@Tang2007]. Depending on the \emph{EHHS} estimator considered (respectively, $\mathrm{EHHS}^{\text{Sab}}$ and $\mathrm{EHHS}^{\text{Tang}}$), two different \emph{iES} estimators, that we further denoted as $\mathrm{iES}^{\text{Sab}}$ and $\mathrm{iES}^{\text{Tang}}$ respectively, can be computed. As for \emph{iHH}, the \emph{iES} integral is computed using the trapezoid method and might only be computed for the regions of the curve above an arbitrarily small \emph{EHHS} value (e.g., \emph{EHHS}>0.05). + +###Dealing with missing data + +In the computation of both \emph{EHH} and \emph{EHHS} from a focal SNP $s$ to a SNP $t$, only extended haplotypes with no missing data are considered. As a consequence, the number of extended haplotypes retained to compute these two statistics might decrease with distance from the focal SNP. However if the number of available extended haplotypes falls below a threshold (e.g., \texttt{limhaplo}=5), \emph{EHH} and \emph{EHHS} are not computed further. Note however that most phasing programs (such as \emph{fastPHASE} or \emph{SHAPEIT2}) allow to impute missing genotypes resulting in phased haplotypes with no missing data. + +##The function \texttt{calc\_ehh()} +\label{calcehh} +The \texttt{calc\_ehh()} function allows to compute \emph{EHH} for both the ancestral ($a_s=1$) and derived ($a_s=2$) alleles at the $s^\text{th}$ SNP relative to each SNP ($t$) upstream and downstream and corresponding \emph{iHH}. The two options \texttt{limehh} and \texttt{limhaplo} allow to specify condition to stop computing \emph{EHH} (see \ref{EHH}). By default \texttt{limehh}=0.05 and \texttt{limhaplo}=2. Finally, if \texttt{plotehh=TRUE}, the decay of \emph{EHH} for both the ancestral and derived alleles is plotted against SNP map position (\texttt{main\_leg} allows to change the plot legend). More details are available in the R documentation by using the command: +```{r eval=FALSE} +?calc_ehh +``` +In the following example,the \emph{EHH} statistics are computed for both the ancestral and derived allele of the $456^{\text{th}}$ focal SNP. Note that the \texttt{haplohh\_cgu\_bta12} object was generated using the \texttt{data2haplohh()} function with the example input files (\ref{LoadDataEx1}). For convenience, it is stored as an example object (accessible with the R function \texttt{data}) as shown below: +```{r, fig.align='center',fig.keep='all'} +#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details +data(haplohh_cgu_bta12) +#computing EHH statistics for the focal SNP at position 456 +#which display a strong signal of selection +res.ehh<-calc_ehh(haplohh_cgu_bta12,mrk=456) +``` +The five different elements of the resulting \texttt{res.ehh} object are as follows: +```{r} +res.ehh$ehh[1:2,454:458] +``` +```{r} +res.ehh$nhaplo_eval[1:2,454:458] +``` +```{r} +res.ehh$freq_all1 +``` +```{r} +res.ehh$ihh +``` +In addition, as \texttt{plotehh=TRUE} by default, we obtain the following plot (Figure \ref{fig:ehhplot}): +```{r ehhplot,echo=FALSE,fig.align='center',,out.height="7cm",fig.cap='Graphical output for the \\texttt{calc\\_ehh()} function',fig.pos='!h',fig.lp='fig:'} +sel_reg <- (colSums(res.ehh$nhaplo_eval) > 0) ; mrk=456 +matplot(haplohh_cgu_bta12@position[sel_reg]/1000000, t(res.ehh$ehh[, sel_reg]),col = c("red", "blue"), lty = 1, type = "l",main = "", bty = "n", xlab = "Position (Mb)",ylab = expression(Extended ~ haplotype ~ homozygosity ~ (italic(EHH)))) +abline(v = haplohh_cgu_bta12@position[mrk]/1000000, lty = 2) +legend("topleft", c("Ancestral Allele", "Derived Allele"),col = c("red", "blue"), bty = "n", lty = 1) +``` + +##The function \texttt{calc\_ehhs()} + +The \texttt{calc\_ehhs()} function allows to compute the \emph{EHHS} (both the $\mathrm{EHHS}^{\text{Sab}}$ and $\mathrm{EHHS}^{\text{Tang}}$ estimators) at the $s^\text{th}$ SNP relative to each SNP ($t$) upstream and downstream. This function also compute the corresponding \emph{iES} ($\mathrm{iES}^{\text{Sab}}$ and $\mathrm{iES}^{\text{Tang}}$ estimators respectively). The two options \texttt{limehhs} and \texttt{limhaplo} allow to specify condition to stop computing \emph{EHHS} (see \ref{EHHS}). By default \texttt{limehhs}=0.05 and \texttt{limhaplo}=2. Finally, if \texttt{plotehhs=TRUE}, the decay of \emph{EHHS} is plotted against SNP map position (\texttt{main\_leg} allows to change the plot legend). More details are available in the R documentation by using the command: +```{r, eval=FALSE} +?calc_ehhs +``` +In the following example, the \emph{EHHS} statistics are computed for the $456^{\text{th}}$ focal SNP on the \texttt{haplohh\_cgu\_bta12} object defined above (see \ref{calcehh}) was generated using the \texttt{data2haplohh()} function with the example input files (see \ref{LoadDataEx1}) described above. For convenience, it is stored as an example object (accessible with the R function \texttt{data}). + +```{r} +#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details +data(haplohh_cgu_bta12) +#computing EHH statistics for the focal SNP at position 456 +#which display a strong signal of selection +res.ehhs<-calc_ehhs(haplohh_cgu_bta12,mrk=456) +``` +The five different elements of the resulting \texttt{res.ehhs} object are as follows: +```{r} +res.ehhs$EHHS_Sabeti_et_al_2007[453:459] +``` +```{r} +res.ehhs$EHHS_Tang_et_al_2007[453:459] +``` +```{r} +res.ehhs$nhaplo_eval[453:459] +``` +```{r} +res.ehhs$IES_Tang_et_al_2007 +``` +```{r} +res.ehhs$IES_Sabeti_et_al_2007 +``` +In addition, as \texttt{plotehh=TRUE} by default, we obtain the following plot (Figure \ref{fig:ehhsplot}): +```{r ehhsplot,echo=FALSE,fig.align='center',out.height="7cm",fig.cap='Graphical output for the \\texttt{calc\\_ehhs()} function',fig.pos='!h',fig.lp='fig:'} +sel_reg <- (colSums(res.ehh$nhaplo_eval) > 0) ; mrk=456 +plot(haplohh_cgu_bta12@position[sel_reg]/1000000, res.ehhs$EHHS_Sabeti_et_al_2007[sel_reg],col = "red", lty = 1, type = "l",main = "", bty = "n", xlab = "Position (Mb)",ylab = expression(Site ~ specific ~ italic(EHH) ~ (italic(EHHS)) )) +lines(haplohh_cgu_bta12@position[sel_reg]/1000000, res.ehhs$EHHS_Tang_et_al_2007[sel_reg], col = "blue") +abline(v = haplohh_cgu_bta12@position[mrk]/1000000, lty = 2) +legend("topleft", c("Sabeti et al. (2007)", "Tang et al. (2007)"),col = c("red", "blue"), bty = "n", lty = 1) +``` + +##The function \texttt{scan\_hh()} +\label{fun.scanhh} +The \texttt{scan\_hh()} function allows to efficiently compute \emph{IHH} (for both the ancestral and derived alleles) and \emph{IES} (both the $\mathrm{iES}^{\text{Sab}}$ and $\mathrm{iES}^{\text{Tang}}$ estimators) for all the SNPs in the \texttt{haplohh} object considered. The options \texttt{limehh}, \texttt{limehhs} and \texttt{limhaplo} specify conditions to stop computing \emph{EHH} and \emph{EHHS}. By default \texttt{limehh}=\texttt{limehhs}=0.05 and \texttt{limhaplo}=2. Finally, the option \texttt{threads}, set by dafault to \texttt{threads}=1, allows to specify the number of available threads to parallelize computation (parallelization being carried out over SNPs). +For instance to scan the \texttt{haplohh\_cgu\_bta12} object (containing data on 1424 SNPs for 280 haplotypes), one may use the following command: +```{r,eval=TRUE} +data(haplohh_cgu_bta12) +res.scan<-scan_hh(haplohh_cgu_bta12) +``` +The resulting object \texttt{res.scan} is a data frame with \texttt{haplohh\_cgu\_bta12\@nsnp} (number of SNPs declared in the \texttt{haplohh} object) and seven columns giving for each SNP: + +1. The SNP chromosome of origin +2. The SNP position +3. The SNP ancestral allele frequency +4. The estimated \emph{IHH} for the ancestral allele (\emph{IHH\_A}) +5. The estimated \emph{IHH} for the derived allele (\emph{IHH\_D}) +6. The estimated $\mathrm{iES}^{\text{Tang}}$ +7. The estimated $\mathrm{iES}^{\text{Sab}}$. + +As an example, the following R codes provide the dimension and the first five rows of the \texttt{res.scan} data frame obtained above: +```{r} +dim(res.scan) +``` +```{r} +head(res.scan) +``` +Note that running \texttt{scan\_hh()} is more efficient than running \texttt{calc\_ehh()} and \texttt{calc\_ehhs()} in turn as shown in the example below (\texttt{scan\_hh()}:. +```{r} +system.time(res.scan<-scan_hh(haplohh_cgu_bta12)) +``` +```{r} +foo<-function(haplo){ +res.ihh=res.ies=matrix(0,haplo@nsnp,2) +for(i in 1:length(haplo@position)){ + res.ihh[i,]=calc_ehh(haplo,mrk=i,plotehh=FALSE)$ihh + tmp=calc_ehhs(haplo,mrk=i,plotehhs=FALSE) + res.ies[i,1]=tmp$IES_Tang_et_al_2007 + res.ies[i,2]=tmp$IES_Sabeti_et_al_2007 +} +list(res.ies=res.ies,res.ihh=res.ihh) +} +system.time(res.scan2<-foo(haplohh_cgu_bta12)) +``` +Note however that the same results are obtained (since the same options were used) as illustrated by the following R code: +```{r} +sum(res.scan2$res.ihh[,1]!=res.scan[,4]) + sum(res.scan2$res.ihh[,2]!=res.scan[,5]) + +sum(res.scan2$res.ies[,1]!=res.scan[,6]) + sum(res.scan2$res.ies[,2]!=res.scan[,7]) +``` +#Computing \emph{iHS}, \emph{Rsb} and \emph{xpEHH}: the \texttt{ihh2ihs()},\texttt{ies2rsb()} and \texttt{ies2xpehh()} functions + +##Within population test: the \emph{iHS} +###Definition +\label{def.ihs} +Let $\mathrm{UniHS}$ represent the log-ratio of the \emph{iHH} for its ancestral (\emph{iHH}$_a$) and derived (\emph{iHH}$_d$) alleles: +$$\mathrm{UniHS}=\log\left(\frac{\mathrm{iHH}_a}{\mathrm{iHH}_d}\right)$$ +The \emph{iHS} of a given focal SNP $s$ ($\mathrm{iHS}(s)$) is then defined as its standardized $\mathrm{UniHS}$ ($\mathrm{UniHS}(s)$) following [@Voight2006]: +$$\mathrm{iHS}(s)=\frac{\mathrm{UniHS}(s) - \mu^{p_s}_\mathrm{UniHS}}{\sigma^{p_s}_\mathrm{UniHS}}$$ +where $\mu^{p_s}_\mathrm{UniHS}$ and $\sigma^{p_s}_\mathrm{UniHS}$ represent the average and standard deviation of the $\mathrm{UniHS}$ computed over all the SNPs with a derived allele frequency $p_s$ similar to that of the core SNP $s$. In practice, the derived allele frequencies are generally binned so that each bin are large enough (e.g., >10 SNPs) to obtain reliable estimate of $\mu^{p_s}_\mathrm{UniHS}$ and $\sigma^{p_s}_\mathrm{UniHS}$. + +Note that the \emph{iHS} is constructed to have an approximately standard Gaussian distribution and to be comparable across SNPs regardless of their underlying allele frequencies. Hence, one may further transform \emph{iHS} into $p_\mathrm{iHS}$ [@Gautier2011]: +$$p_\mathrm{iHS}=-\log_{10}\left(1-2|\Phi\left(\mathrm{iHS}\right)-0.5|\right)$$ +where $\Phi\left(x\right)$ represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical \emph{iHS} distribution is a fair approximation of the neutral distribution), $p_\mathrm{iHS}$ might thus be interpreted as a two-sided P-value (on a $-\log_{10}$ scale) associated to the neutral hypothesis of no selection. + +###The function \texttt{ihh2ihs()} +\label{cgu.ihs} +The \texttt{ihh2ihs()} function allows to compute \emph{iHS} using a matrix of \emph{iHH} statistics (for both the ancestral and derived alleles) in the same format as obtained from the \texttt{scan\_hh()} function (see \ref{fun.scanhh}). The argument \texttt{minmaf} allows to remove SNPs according to their MAF (by default SNPs with a MAF<\texttt{minmaf}=0.05 are discarded from the standardization). The argument \texttt{freqbin} controls the size of the allele frequency bins used to perform standardization (see \ref{def.ihs}). More precisely allele frequency bins vary from \texttt{minmaf} to 1-\texttt{minmaf} per step of size \texttt{freqbin} (by default \texttt{freqbin}=0.025). Note that if \texttt{freqbin} is set to 0 (e.g., with a large number of SNPs and few haplotypes), standardization is performed considering each observed frequency as a frequency class. + +For instance, to perform a whole genome scan one might run \texttt{scan\_hh()} in turn on haplotype data from each chromosome and concatenate the resulting matrices before standardization. In the following example, we assume that the haplotype files are named as \texttt{hap\_chr\_i.pop1} where the chromosome number $i$ goes from 1 to 29 and the SNP information file is named \texttt{snp.info}. The R code below then generates a matrix \texttt{wg.res} with \emph{iHH$_a$} and \emph{iHH$_d$} estimates for all SNPs in an appropriate format to perform standardization with the \texttt{ihh2ihs} function: +```{r,eval=FALSE} +for(i in 1:29){ + hap_file=paste("hap_chr_",i,".pop1",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res<-res}else{wg.res<-rbind(wg.res,res)} + } +wg.ihs<-ihh2ihs(wg.res) +``` +As a matter of illustration, results of a similar genome scan [@Gautier2011] are provided as example data sets. The following R code allows to compute the \emph{iHS} for the CGU population: +```{r} +data(wgscan.cgu) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +ihs.cgu<-ihh2ihs(wgscan.cgu) +``` +The corresponding object \texttt{ihs.cgu} is a list with two elements corresponding to + +1. a matrix of SNP \emph{iHS} and the corresponding $p_\mathrm{iHS}$ (P-values in a $-\log_10$ scale assuming the \emph{iHS} are normally distributed under the neutral hypothesis). For instance, the five first rows of the \texttt{ihs.cgu\$iHS} data frame are displayed below using the following R command: +```{r} +head(ihs.cgu$iHS) +``` +2.a matrix summarizing the allele frequency bins. For instance, the five first rows of the \texttt{ihs.cgu\$frequency.class} data frame are displayed below using the following R command: +```{r} +head(ihs.cgu$frequency.class) +``` + +###Manhattan plot of the results: the function \texttt{ihsplot()} + +The \texttt{ihsplot()} function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the list object produced by the function \texttt{ihh2ies()}. Various options are available to modify the graphical display (see \texttt{?ihsplot}). +```{r,eval=FALSE} +ihsplot(ihs.cgu,plot.pval=TRUE,ylim.scan=2,main="iHS (CGU cattle breed)") + +``` + +```{r ,echo=FALSE,fig.ext="png",fig.align='center',fig.width=16,fig.height=12,fig.cap='Graphical output for the \\texttt{ihsplot()} function'} +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "iHS (CGU cattle breed)"; cex.main = 1.;cex.axis=0.7 +data = ihs.cgu$iHS +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$iHS, pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(iHS)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +``` + +##The \emph{Rsb}--based pairwise population test +###Definition +For a given SNP $s$, let $$\mathrm{LRiES}(s)^{\text{Tang}}=\log\left(\frac{\mathrm{iES}_\text{pop1}(s)^{\text{Tang}}}{\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}}\right)$$ represent the log-ratio of the $\mathrm{iES}_\text{pop1}(s)^{\text{Tang}}$ and $\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}$ computed in the pop1 and pop2 populations (see \ref{iES}). + +The \emph{Rsb} for a given focal SNP is then defined as the standardized $\mathrm{LRiES}(s)^{\text{Tang}}$ [@Tang2007]: + +\begin{equation} +\mathrm{rSB}(s)=\frac{\mathrm{LRiES}(s)^{\text{Tang}} - \text{med}_{\mathrm{LRiES}^{\text{Tang}}}}{\sigma_{\mathrm{LRiES}^{\text{Tang}}}} +\end{equation} +where $\text{med}_{\mathrm{LRiES}^{\text{Tang}}}$ and $\sigma_{\mathrm{LRiES}^{\text{Tang}}}$ represent the median and standard deviation of the $\mathrm{LRiES}(s)^{\text{Tang}}$ computed over all the analyzed SNPs. Note that the median is used instead of the mean because it is less sensitive to extreme data points [@Tang2007]. +More importantly, it should be noticed that the information about the ancestral and derived status of alleles at the focal SNP is not needed. + +As for the \emph{iHS} (see \ref{def.ihs}), \emph{Rsb} is constructed to have an approximately standard Gaussian distribution and may further be transformed into $p_\mathrm{rSB}$: +\begin{equation} +p_\mathrm{rSB}=-\log_{10}\left(1-2|\Phi\left(\mathrm{rSB}\right)-0.5|\right) +\end{equation} +where $\Phi\left(x\right)$ represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical \emph{Rsb} distribution is a fair approximation of their corresponding neutral distributions), $p_\mathrm{rSB}$ might thus be interpreted as a two-sided P-value (in a $-\log_{10}$ scale) associated to the neutral hypothesis of no selection. +Alternatively, $p_\mathrm{rSB}$ might also be computed [@Gautier2011]: +\begin{equation} +p\prime_\mathrm{rSB}=-\log_{10}\left(|\Phi\left(\mathrm{rSB}\right)|\right) +\end{equation} +$p\prime_\mathrm{rSB}$ and $p\prime_\mathrm{rSB}$ might then be interpreted as a one-sided P-value (in a $-\log_{10}$ scale) allowing the identification of those sites displaying a significantly high extended haplotype homozygosity in population $pop2$ (represented in the denominator of the corresponding $\mathrm{LRiES}$) relatively to the $pop1$ reference population. + +###The function \texttt{ies2rsb()} +\label{res.rsb} + +The \texttt{ies2rsb()} function allows to compute \emph{Rsb} using two data frames containing the \emph{iES} statistics for each of the two populations considered in the same format as the one obtained after running the \texttt{scan\_hh()} function (see \ref{fun.scanhh}). +For instance, to perform a genome scan one might first run for each population \texttt{scan\_hh()} in turn on haplotype data from each chromosome and concatenate the resulting matrices. In the following example, we assume that the haplotype files are named as \texttt{hap\_chr\_i.pop1} and \texttt{hap\_chr\_i.pop2} where $i$ is the chromosome number (going from 1 to 29), the suffixes pop1 and pop2 indicate the population of origin and the SNP information file is named \texttt{snp.info}. The R code below then generates two data frames (\texttt{wg.res.pop1} and \texttt{wg.res.pop2}) containing the results from all SNPs in the appropriate format to compute \emph{Rsb} with the \texttt{ies2rsb()} function: + +```{r,eval=FALSE} +for(i in 1:29){ + hap_file=paste("hap_chr_",i,".pop1",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)} + hap_file=paste("hap_chr_",i,".pop2",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)} + } +wg.rsb<-ies2rsb(wg.res.pop1,wg.res.pop2) +``` +As a matter of illustration, one may consider results from a similar genome scan [@Gautier2011] provided as example data sets and compute for each SNP the \emph{Rsb} between the CGU and EUT populations as follows: +```{r} +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +cguVSeut.rsb<-ies2rsb(wgscan.cgu,wgscan.eut,"CGU","EUT") +``` + +The resulting object \texttt{cguVSeut.rsb} is a data frame with of SNP \emph{Rsb} (and corresponding P-Values assuming \emph{Rsb} are normally distributed under the neutral hypothesis). Note that either bilateral (default) or unilateral might be performed (\texttt{method} argument). The five first rows of the \texttt{cguVSeut.rsb} data frame are displayed below using the following R command: + +```{r} +head(cguVSeut.rsb) +``` +###Manhattan plot of the results: the function \texttt{rsbplot()} + +The \texttt{rsbplot()} function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the data frame produced by the function \texttt{ies2rsb()}. Various options are available to modify the graphical display (see \texttt{?rsbplot}). As an example, the Figure \ref{fig:rsbplot} below provides the output of the function \texttt{rsbplot} for the \emph{xpEHH} computed above across the CGU and EUT populations (see \ref{res.rsb}). Figure \ref{fig:rsbplot} was drawn using the following R code: +```{r,eval=FALSE} +rsbplot(cguVSeut.rsb,plot.pval=TRUE) +``` + +```{r rsbplot,echo=FALSE,fig.ext="png",fig.align='center',fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the \\texttt{rsbplot()} function',fig.pos='!h'} +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "Rsb (CGU vs. EUT)"; cex.main = 1.;cex.axis=0.7 +data = cguVSeut.rsb +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data[,3], pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(Rsb)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +``` + +##The \emph{xpEHH}--based pairwise population test +###Definition +The \emph{xpEHH} statistics [@Sabeti2007] is similar to the \emph{Rsb} except that it is based on the $\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}$ (instead of $\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}$) estimator of the \emph{iES} (see \ref{iES}). Hence, for or a given SNP $s$, let $$\mathrm{LRiES}(s)^{\text{Sab}}=\log\left(\frac{\mathrm{iES}_\text{pop1}(s)^{\text{Sab}}}{\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}}\right)$$ represent the log-ratio of the $\mathrm{iES}_\text{pop1}(s)^{\text{Sab}}$ and $\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}$ computed in the pop1 and pop2 populations (see \ref{iES}). + +The \emph{xpEHH} for a given focal SNP is then defined as the standardized $\mathrm{LRiES}(s)^{\text{Sab}}$ [@Sabeti2007]: + +\begin{equation} +\mathrm{rSB}(s)=\frac{\mathrm{LRiES}(s)^{\text{Sab}} - \text{med}_{\mathrm{LRiES}^{\text{Sab}}}}{\sigma_{\mathrm{LRiES}^{\text{Sab}}}} +\end{equation} +where $\text{med}_{\mathrm{LRiES}^{\text{Sab}}}$ and $\sigma_{\mathrm{LRiES}^{\text{Sab}}}$ represent the median and standard deviation of the $\mathrm{LRiES}(s)^{\text{Sab}}$ computed over all the analyzed SNPs. +More importantly, it should be noticed that the information about the ancestral and derived status of alleles at the focal SNP is not needed. + +As for the \emph{iHS} (see \ref{def.ihs}) and \emph{Rsb}, \emph{xpEHH} is constructed to have an approximately standard Gaussian distribution and may further be transformed into $p_\mathrm{xpEHH}$: +\begin{equation} +p_\mathrm{xpEHH}=-\log_{10}\left(1-2|\Phi\left(\mathrm{xpEHH}\right)-0.5|\right) +\end{equation} +where $\Phi\left(x\right)$ represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical \emph{xpEHH} distribution is a fair approximation of their corresponding neutral distributions), $p_\mathrm{xpEHH}$ might thus be interpreted as a two-sided P-value (in a $-\log_{10}$ scale) associated to the neutral hypothesis of no selection. +Alternatively, $p_\mathrm{xpEHH}$ might also be computed [@Gautier2011]: +\begin{equation} +p\prime_\mathrm{xpEHH}=-\log_{10}\left(|\Phi\left(\mathrm{xpEHH}\right)|\right) +\end{equation} +$p\prime_\mathrm{xpEHH}$ and $p\prime_\mathrm{xpEHH}$ might then be interpreted as a one-sided P-value (in a $-\log_{10}$ scale) allowing the identification of those sites displaying a significantly high extended haplotype homozygosity in population $pop2$ (represented in the denominator of the corresponding $\mathrm{LRiES}$) relatively to the $pop1$ reference population. + +###The function \texttt{ies2xpehh()} +\label{res.xpehh} + +The \texttt{ies2xpehh()} function allows to compute \emph{xpEHH} using two data frames containing the \emph{iES} statistics for each of the two populations considered in the same format as the one obtained after running the \texttt{scan\_hh()} function (see \ref{fun.scanhh}). +For instance, to perform a genome scan one might first run for each population \texttt{scan\_hh()} in turn on haplotype data from each chromosome and concatenate the resulting matrices. In the following example, we assume that the haplotype files are named as \texttt{hap\_chr\_i.pop1} and \texttt{hap\_chr\_i.pop2} where $i$ is the chromosome number (going from 1 to 29), the suffixes pop1 and pop2 indicate the population of origin and the SNP information file is named \texttt{snp.info}. The R code below then generates two data frames (\texttt{wg.res.pop1} and \texttt{wg.res.pop2}) containing the results from all SNPs in the appropriate format to compute \emph{Rsb} with the \texttt{ies2rsb()} function: + +```{r,eval=FALSE} +for(i in 1:29){ + hap_file=paste("hap_chr_",i,".pop1",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)} + hap_file=paste("hap_chr_",i,".pop2",sep="") + data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i) + res<-scan_hh(data) + if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)} + } +wg.xpehh<-ies2xpehh(wg.res.pop1,wg.res.pop2) +``` +As a matter of illustration, one may consider results from a similar genome scan [@Gautier2011] provided as example data sets and compute for each SNP the \emph{xpEHH} between the CGU and EUT populations as follows: +```{r} +data(wgscan.cgu) ; data(wgscan.eut) +## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details +cguVSeut.xpehh<-ies2xpehh(wgscan.cgu,wgscan.eut,"CGU","EUT") +``` + +The resulting object \texttt{cguVSeut.xpehh} is a data frame with of SNP \emph{xpEHH} (and corresponding P-values assuming \emph{xpEHH} are normally distributed under the neutral hypothesis). Note that either bilateral (default) or unilateral might be performed (\texttt{method} argument). The five first rows of this data frame are displayed below using the following R command: + +```{r} +head(cguVSeut.xpehh) +``` +###Manhattan plot of the results: the function \texttt{xpehhplot()} + +The \texttt{xpehhplot()} function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the data frame produced by the function \texttt{ies2xpehh()}. Various options are available to modify the graphical display (see \texttt{?xpehhplot}). +As an example, the Figure \ref{fig:xpehhplot} below provides the output of the function \texttt{xpehhplot} for the \emph{xpEHH} computed above across the CGU and EUT populations (see \ref{res.xpehh}). Figure \ref{fig:xpehhplot} was drawn using the following R code: + +```{r,eval=FALSE} +xpehhplot(cguVSeut.xpehh,plot.pval=TRUE) +``` + +```{r xpehhplot,echo=FALSE,fig.align='center',fig.ext="png",fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the \\texttt{xpehhplot()} function',fig.pos="!h"} +layout(matrix(1:2,2,1)) +plot.pval = TRUE; ylim.scan = 2; pch = 16; cex = 0.75; cex.lab = 1; main = "Rsb (CGU vs. EUT)"; cex.main = 1.;cex.axis=0.7 +data = cguVSeut.xpehh +lst_chrm <- unique(data$CHR) ; nbr_chrm <- length(lst_chrm) ; cum <- rep(0, (nbr_chrm + 1)) +if (nbr_chrm > 1) { + for (i in 1:nbr_chrm) {cum[i + 1] <- tail(data$POSITION[data$CHR == lst_chrm[i]],n = 1)} +} +cum <- cumsum(cum) ; pos <- rep(0, length(data$CHR)) ; pos_labels <- rep(0, nbr_chrm) +for (i in 1:nbr_chrm) { + pos[data$CHR == lst_chrm[i]] <- data$POSITION[data$CHR ==lst_chrm[i]] + cum[which(lst_chrm == lst_chrm[i])] + pos_labels[i] <- (cum[i] + cum[i + 1])/2 +} +col_chr <- data$CHR +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data[,3], pch = pch, cex = cex, las = 1, col = col_chr,xaxt = "n", xlab = "Chromosome", ylab = expression(italic(XPEHH)), + cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +par(mar = c(5, 5, 4, 2) + 0.1) +plot(pos, data$"-log10(p-value)", pch = pch, cex = cex,las = 1, col = col_chr, xaxt = "n", xlab = "Chromosome", + ylab = expression("-" * log[10] * "[1" ~ "-" ~"2" ~ "|" ~ Phi[scriptstyle(italic(iHS))] ~"-" ~ 0.5 * "|]"), cex.lab = cex.lab, main = main, cex.main = cex.main,cex.axis=cex.axis) +axis(1, at = pos_labels, labels = lst_chrm, las = 1,cex.lab=cex.lab,cex.axis=cex.axis) +abline(h = c(-ylim.scan, ylim.scan), lty = 2) +``` +###\emph{xpEHH} vs. \emph{Rsb} comparison: + +A plot of the \emph{xpEHH} against \emph{Rsb} estimates across the CGU and EUT populations (see \ref{res.xpehh} and \ref{res.rsb} respectively) is represented in the Figure \ref{fig:comp} below. This figure was generated using the following R code: + +```{r comp,echo=TRUE,fig.align='center',fig.ext="png",out.height="7cm",fig.lp='fig:',fig.cap='Comparison of the XPEHH and Rsb estimates across the CGU and EUT populations',fig.pos="!h"} +plot(cguVSeut.rsb[,3],cguVSeut.xpehh[,3],xlab="Rsb",ylab="XPEHH",pch=16, + cex=0.5,cex.lab=0.75,cex.axis=0.75) +abline(a=0,b=1,lty=2) +``` +##Visual inspection of the standardized scores distribution: the function \texttt{distribplot()} + +The \texttt{distribplot} function allows to easily visualize the distributions of the standardized scores (either \emph{iHS}, \emph{Rsb} or \emph{xpEHH}) and compare them to the standard Gaussian distribution. As an example, the Figure \ref{fig:distribplot} below provides the output the function \texttt{distribplot} when considering the \emph{iHS} estimates obtained for the CGU population (see \ref{cgu.ihs}) using the following R code: + +```{r,eval=FALSE} +distribplot(ihs.cgu$iHS[,3],xlab="iHS") +``` + +```{r distribplot,echo=FALSE,fig.align='center',fig.width=7,out.height="7cm",fig.height=7,fig.lp='fig:',fig.cap='Graphical output for the function \\texttt{distribplot}',fig.pos="!h"} +layout(matrix(1:2,2,1)) +data=ihs.cgu$iHS[,3] +lty = 1;lwd = 1.5;col = c("blue","red");main = "Genome-wide distribution";xlab = "iHS";cex.main = 1.5;cex.lab = 1.25;qqplot = TRUE +plot(density(data,na.rm = TRUE),main = main,xlab = xlab,col = col[1],lty = lty,lwd = lwd,cex.main = cex.main,cex.lab = cex.lab) + curve(dnorm,col = col[2],add = TRUE) + legend("topright",c("Observed","Gaussian"),bty = "n",col = col,lty = lty,lwd = lwd) + if (qqplot) { + par(mar = c(5,5,4,2) + 0.1) + qqnorm(data[!is.na(data)],cex.main = cex.main,cex.lab = cex.lab,pch = 16,cex = 0.75) + abline(a=0,b=1,lty=2) + } +``` + +#Visualizing haplotype structure around a core allele: the function \texttt{bifurcation.diagram()} + +The function \texttt{bifurcation.diagram()} function draws haplotype bifurcation diagrams [@Sabeti2002] that allow to better understand the origin of an observed footprints of selection. Such diagrams indeed consist in plotting the breakdown of LD at increasing distances from the core allele at the selected focal SNPs. The root (focal SNP) of each diagram is the core allele and is here identified by a vertical dashed line. +The diagram is bi-directional, portraying both centromere-proximal and centromere-distal LD. Moving in one direction, each marker is an opportunity for a node; the diagram either divides or not based on whether both or only one allele is present. Thus the breakdown of LD on the core haplotype background is portrayed at progressively longer distances. The thickness of the lines corresponds to the number of samples with the indicated long-distance haplotype. Several options are available to modify the aspect of the plots (see command \texttt{?bifurcation.diagram}) +As a matter of illustration, Figure \ref{fig:bifdia} shows the bifurcation diagrams for both the derived and ancestral alleles at the $456^{\text{th}}$ SNP on BTA12 CGU haplotypes. This SNP displayed a strong signal of selection (using both \emph{iHS} and \emph{Rsb} statistics) and is located closed (<5kb) to a strong candidate genes involved in horn development [@Gautier2011]. Figure \ref{fig:bifdia} was obtained with the following R code: + +```{r bifdia,eval=TRUE,fig.align='center',out.height="12cm",fig.width=16,fig.height=12,fig.lp='fig:',fig.cap='Graphical output for the function \\texttt{bifurcation.diagram()}',fig.pos="!h"} +data(haplohh_cgu_bta12) +layout(matrix(1:2,2,1)) +bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=1,nmrk_l=20,nmrk_r=20, + main="Bifurcation diagram (RXFP2 SNP on BTA12): Ancestral Allele") +bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=2,nmrk_l=20,nmrk_r=20, + main="Bifurcation diagram (RXFP2 SNP on BTA12): Derived Allele") +``` + +\clearpage +\newpage + +#References diff --git a/vignettes/rehh.html b/vignettes/rehh.html new file mode 100644 index 0000000..d53de67 --- /dev/null +++ b/vignettes/rehh.html @@ -0,0 +1,774 @@ + + + + + + + + + + + + + + + +Vignette for the package rehh (version 2+) + + + + + + + + + + + + + + + + + + + + + + + + + + +
+ + + + + + + + + + + + + + + + +\newpage + +

This vignette is aimed at presenting additional information on the R package by describing how to use it to perform whole genome scan for footprints of selection using statistics related to the Extended Haplotype Homozygosity (EHH) (Sabeti et al. 2002). Importantly, the current implementation of tests assumes markers are bi-allelic.

+

The package is currently available for most platforms (Linux, MS Windows and MacOSX) from the CRAN repository () and may be installed using standard procedure. Once the package has been successfully installed on your system, it can be loaded using the following command:

+
library(rehh)
+
+

Input Files

+

+

The package basically requires as input:

+
    +
  1. haplotype data file(s) (in three possible format) for each population of interest (see )
  2. +
  3. a SNP information file (see )
  4. +
+

Important Note: For a given chromosome, SNPs are assumed to be ordered in the same way in both the haplotype file (columns) and the SNP information file.

+

For illustration purposes, example files that originate from a previously published study on the Creole cattle breed from Guadeloupe (CGU) (Gautier and Naves 2011) are provided in the package and can be copied in the working directory with the following command:

+
make.example.files()
+

In the following examples, the command is assumed to have been run (see above) so that example files are in the working directory.

+
+

Haplotype data file

+

+

Three haplotype input file formats are supported:

+
    +
  1. a standard haplotype format. Each line represents a haplotype (the first element being an haplotype identifier) with SNP genotype in columns as in the example file created when running the function and that consists of 280 haplotypes (identifier 1 to 280) of 1424 SNPs each. See for a detailed example.
  2. +
  3. A (transposed) format with haplotype in columns and SNPs in row as in the example file created when running the function . Note that this format is similar to the one produced by the phasing program (O’Connell et al. 2014). See for a detailed example.
  4. +
  5. the output file format from the phasing program (Scheet and Stephens 2006) as in the example file created when running the function . Note that haplotypes might originate from several different populations (i.e., if the -u option was used). See for a detailed example.
  6. +
+

By default alleles are assumed to be coded as 0 (missing data), 1 (ancestral allele) or 2 (derived allele). Recoding of the alleles in this format, according to the SNP information data file (see ) can be performed with the option of the function (see ).

+
+
+

SNP information data file

+

+

This data file should contain SNP information as in the example file created when running the function . Each line contains five columns corresponding to:

+
    +
  1. the SNP name
  2. +
  3. the SNP chromosome (or scaffold) of origin
  4. +
  5. the SNP position on the chromosome (or scaffold). Note that it is up to the user to choose either physical or genetic map positions (if available).
  6. +
  7. the SNP ancestral allele (as coded in the haplotype input file)
  8. +
  9. the SNP derived alleles (as coded in the haplotype input file)
  10. +
+

The fourth and fifth columns (allele coding) should be filled in but the corresponding information is only used when activating the option of the function (see ). In that case, for each SNP, the allele specified in the fourth (respectively fifth) column will be recoded as 1 (respectively 2), any other allele name will be recoded as 0 (i.e., missing data). More importantly, it should be noticed that the ancestral or derived allele information associated to this coding are only relevant for within population tests (based on ). In other words, if one is only interested in across-population tests (based on or ), assignment of the two SNP alleles in the fourth and fifth column may be performed randomly.

+

As an illustration, the following R command displays the first five row of the example file created when running the function :

+
head(read.table("map.inp"))
+
>         V1 V2     V3 V4 V5
+> 1 F0100190  1 113642  T  A
+> 2 F0100220  1 244699  C  G
+> 3 F0100250  1 369419  G  C
+> 4 F0100270  1 447278  A  T
+> 5 F0100280  1 487654  T  A
+> 6 F0100290  1 524507  C  G
+
+
+

Loading data files

+

The function allows to convert data file into an R object of class subsequently used by the functions of the package. The following main options are available to recode alleles or select SNPs (based on Minor Allele Frequency or percentage of missing data) and haplotypes (based on percentage of missing data):

+
    +
  1. Allele recoding option: This option is activated with and allows to recode haplotype according to the ancestral and derived allele definition available in the SNP information file (fourth and fifth columns) as: 0 (missing data), 1 (ancestral allele) or 2 (derived allele).
  2. +
  3. Discard haplotypes with a high amount of missing data. If haplotypes contain missing data (which is generally not the case since most phasing programs allow imputing missing genotypes), it is possible to discard those with less % of the SNPs genotyped. By default meaning that only completely phased haplotypes are retained.
    +
  4. +
  5. Discard SNPs with a high amount of missing data. It is possible to discard SNPs genotyped on less than % of the haplotypes. By default meaning that only fully genotyped SNPs are retained.
  6. +
  7. Discard SNPs with a low Minor Allele Frequency. It is possible to discard SNPs with a MAF below . This is generally not recommended and by default meaning that all SNPs are retained.
  8. +
+

More details about the different arguments of the function are available in the documentation accessible using the command:

+
?data2haplohh
+

In the following we detail three different examples based on the example data files provided with the package (see ).

+
+

Example 1: reading haplotype file in standard format

+

In this example, the example haplotype input file (standard format) and SNP information input files are converted into an object named . Because the map file contains information for SNPs mapping to other chromosomes than the one of interest (BTA12), we use the option . Allele recoding is activated () to allow recoding alleles in the format (0,1 or 2).

+
hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp",
+                  recode.allele=TRUE,chr.name=12)
+
> Map file seems OK: 1424  SNPs declared for chromosome 12 
+> Standard rehh input file assumed
+> Alleles are being recoded according to map file as:
+>   0 (missing data), 1 (ancestral allele) or 2 (derived allele)
+> Discard Haplotype with less than  100 % of genotyped SNPs
+> No haplotype discarded
+> Discard SNPs genotyped on less than  100 % of haplotypes
+> No SNP discarded
+> Data consists of 280 haplotypes and 1424 SNPs
+

If no value is specified for argument and more than one chromosome is detected in the map file, the function asks interactively which chromosome to choose:

+
hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp",
+                  recode.allele=TRUE) 
+
> More than one chromosome name in Map file: map.inp
+> Which chromosome should be considered among:
+> 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29
+> 1:
+
12
+
> Map file seems OK: 1424  SNPs declared for chromosome 12 
+> Standard rehh input file assumed
+> Alleles are being recoded according to map file as:
+>   0 (missing data), 1 (ancestral allele) or 2 (derived allele)
+> Discard Haplotype with less than  100 % of genotyped SNPs
+> No haplotype discarded
+> Discard SNPs genotyped on less than  100 % of haplotypes
+> No SNP discarded
+> Data consists of 280 haplotypes and 1424 SNPs
+

Finally, as an example of error message, the following message is prompted if the number of SNPs in the chromosome (for instance when a wrong chromosome is declared) does not correspond to the one in the haplotype file:

+
hap<-data2haplohh(hap_file="bta12_cgu.hap",map_file="map.inp",
+                  recode.allele=TRUE,chr.name=18)
+
> Map file seems OK: 1123  SNPs declared for chromosome 18 
+> Standard rehh input file assumed
+> The number of snp in the haplotypes 1424  is not equal
+> to the number of snps declared in the map file 1123
+
> Error in data2haplohh(hap_file = "bta12_cgu.hap", map_file = "map.inp", : Conversion stopped
+
+
+

Example 2: reading haplotype file in transposed format (–like)

+

+

In this example, the example haplotype input file (transposed format) and SNP information input files are converted into an object named . Setting informs the function that the haplotype file is in transposed format:

+
hap<-data2haplohh(hap_file="bta12_cgu.thap",map_file="map.inp",haplotype.in.columns=TRUE,
+                  recode.allele=TRUE,chr.name=12)
+
> Map file seems OK: 1424  SNPs declared for chromosome 12 
+> Haplotype are in columns with no header
+> Alleles are being recoded according to map file as:
+>   0 (missing data), 1 (ancestral allele) or 2 (derived allele)
+> Discard Haplotype with less than  100 % of genotyped SNPs
+> No haplotype discarded
+> Discard SNPs genotyped on less than  100 % of haplotypes
+> No SNP discarded
+> Data consists of 280 haplotypes and 1424 SNPs
+
+
+

Example 3: reading haplotype file in output format

+

In this example, the example output file and SNP information input files are converted into a object named . As explained above we use the option . Because, haplotypes originate from several populations (the -u option was used), we specify the population of interest (in our example the 280 haplotypes from the CGU population, see above) using the option (7 corresponding to the code of CGU in the example input files).

+
hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp",
+                  recode.allele=TRUE,popsel=7,chr.name=12)
+
> Map file seems OK: 1424  SNPs declared for chromosome 12 
+> Looks like a FastPHASE haplotype file
+> Haplotypes originate from  8  different populations in the fastPhase output file
+> Alleles are being recoded according to map file as:
+>   0 (missing data), 1 (ancestral allele) or 2 (derived allele)
+> Discard Haplotype with less than  100 % of genotyped SNPs
+> No haplotype discarded
+> Discard SNPs genotyped on less than  100 % of haplotypes
+> No SNP discarded
+> Data consists of 280 haplotypes and 1424 SNPs
+

If no value is specified for the argument and more than one population is detected in the output file, the function asks interactively which population to chose:

+
hap<-data2haplohh(hap_file="bta12_hapguess_switch.out",map_file="map.inp",
+                  recode.allele=TRUE,chr.name=12)
+
> Map file seems OK: 1424  SNPs declared for chromosome 12
+> Looks like a FastPHASE haplotype file
+> Haplotypes originate from  8  different populations in the fastPhase output file
+> Chosen pop. is not in the list of pop. number: 1 2 3 4 5 6 7 8
+> Which population should be considered among: 1 2 3 4 5 6 7 8
+> 1:
+
7
+
> Map file seems OK: 1424  SNPs declared for chromosome 12 
+> Looks like a FastPHASE haplotype file
+> Haplotypes originate from  8  different populations in the fastPhase output file
+> Alleles are being recoded according to map file as:
+>   0 (missing data), 1 (ancestral allele) or 2 (derived allele)
+> Discard Haplotype with less than  100 % of genotyped SNPs
+> No haplotype discarded
+> Discard SNPs genotyped on less than  100 % of haplotypes
+> No SNP discarded
+> Data consists of 280 haplotypes and 1424 SNPs
+
+
+
+
+

Computing -based statistics for individual markers with the , and functions

+
+

Definition and Computation

+
+

The (allele-specific) Extended Haplotype Homozygosity ()

+ For a given core allele (i.e., the ancestral or derived allele) at a focal SNP, the (allele–specific) extended haplotype homozygosity () is defined as the probability that two randomly chosen chromosomes (carrying the core allele considered) are identical by descent (as assayed by homozygosity at all SNPs) over a given surrounding chromosome region (Sabeti et al. 2002). The thus aims at measuring to which extent an extended haplotype is transmitted without recombination. In practice, the (\(\mathrm{EHH}_{s,t}\)) of a tested core allele \(a_s\) (\(a_s=1\) or \(a_s=2\)) for a focal SNP \(s\) over the chromosome interval extending to SNP \(t\) is computed as: +\begin{equation} +\label{ehh.def} +\mathrm{EHH}_{s,t}=\frac{1}{n_{a_s}(n_{a_s}-1)}\sum\limits_{k=1}^{K_{a_s,t}}n_k(n_k-1) +\end{equation} +

where \(n_{a_s}\) represents the number of haplotype carrying the core allele \(a_s\), \(K_{a_s,t}\) represents the number of different extended haplotypes (from SNP \(s\) to SNP \(t\)) carrying \(a_s\) and \(n_k\) is the number of the extended haplotype \(k\) (i.e., \(n_{a_s}=\sum\limits_{k=1}^{K_{a_s,t}}n_k\)).

+
+
+

The integrated (allele-specific) ()

+

By definition, irrespective of the allele considered, starts at 1, and decays monotonically to 0 with increasing distance from the focal SNP. For a given core allele, the integrated () is defined as the area under the curve with respect to map position (Voight et al. 2006). In , is computed using the trapezoid method. In practice, the integral might only be computed for the regions of the curve above an arbitrarily small value (e.g., >0.05).

+
+
+

The site-specific Extended Haplotype Homozygosity ()

+ For a given core SNP, the (site–specific) extended haplotype homozygosity () is defined as the probability that two randomly chosen chromosomes are identical by descent (as assayed by homozygosity at all SNPs) over a given surrounding chromosome region. might roughly be viewed as linear combination of the ’s for the two alternative alleles with weights function of the corresponding allele frequencies. Two different estimators further denoted as \(\mathrm{EHHS}^{\text{Sab}}\) (Sabeti et al. 2007) and \(\mathrm{EHHS}^{\text{Tang}}\) (Tang et al. 2007) have been proposed. For a focal SNP \(s\) over a chromosome interval extending to SNP \(t\), these are computed as (following the same notation as above): +\begin{equation} +\label{ehhssab.def} +\mathrm{EHHS}^{\text{Sab}}_{s,t}=\frac{1}{n_s(n_s-1)}\sum\limits_{a_s=1}^{a_s=2}\left(\sum\limits_{k=1}^{K_{a_s,t}}n_k(n_k-1)\right) +\end{equation} +where \(n_s=\sum\limits_{a_s=1}^{a_s=2}n_{a_s}\) and +\begin{equation} +\label{ehhstang.def} +\mathrm{EHHS}^{\text{Tang}}_{s,t}=\frac{1-h_{hap}^{(s,t)}}{1-h_{all}^{(s)}} +\end{equation} +

where:

+
    +
  1. \(h_{all}^{(s)}=\frac{n_s}{n_s-1}\left(1-\frac{1}{n_s^2}\sum\limits_{a_s=1}^{a_s=2}n_{a_s}^2 \right )\) is an estimator of the focal SNP heterozygosity
  2. +
  3. \(h_{hap}^{(s,t)}=\frac{n_s}{n_s-1}\left(1-\frac{1}{n_s^2}\sum\limits_{a_s=1}^{a_s=2}\left(\sum\limits_{k=1}^{K_{a_s,t}}n_k^2 \right )\right)\) is an estimator of haplotype heterozygosity across the chromosome region extending from SNP \(s\) to SNP \(t\).
  4. +
+
+
+

The integrated ()

+

As for the (see ), starts at 1 and decays monotonically to 0 with increasing distance from the focal SNP. For a given focal SNP, and in a similar fashion as the , is defined as the integrated (Tang et al. 2007). Depending on the estimator considered (respectively, \(\mathrm{EHHS}^{\text{Sab}}\) and \(\mathrm{EHHS}^{\text{Tang}}\)), two different estimators, that we further denoted as \(\mathrm{iES}^{\text{Sab}}\) and \(\mathrm{iES}^{\text{Tang}}\) respectively, can be computed. As for , the integral is computed using the trapezoid method and might only be computed for the regions of the curve above an arbitrarily small value (e.g., >0.05).

+
+
+

Dealing with missing data

+

In the computation of both and from a focal SNP \(s\) to a SNP \(t\), only extended haplotypes with no missing data are considered. As a consequence, the number of extended haplotypes retained to compute these two statistics might decrease with distance from the focal SNP. However if the number of available extended haplotypes falls below a threshold (e.g., =5), and are not computed further. Note however that most phasing programs (such as or ) allow to impute missing genotypes resulting in phased haplotypes with no missing data.

+
+
+
+

The function

+

The function allows to compute for both the ancestral (\(a_s=1\)) and derived (\(a_s=2\)) alleles at the \(s^\text{th}\) SNP relative to each SNP (\(t\)) upstream and downstream and corresponding . The two options and allow to specify condition to stop computing (see ). By default =0.05 and =2. Finally, if , the decay of for both the ancestral and derived alleles is plotted against SNP map position ( allows to change the plot legend). More details are available in the R documentation by using the command:

+
?calc_ehh
+

In the following example,the statistics are computed for both the ancestral and derived allele of the \(456^{\text{th}}\) focal SNP. Note that the object was generated using the function with the example input files (). For convenience, it is stored as an example object (accessible with the R function ) as shown below:

+
#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details
+data(haplohh_cgu_bta12)
+#computing EHH statistics for the focal SNP at position 456 
+#which display a strong signal of selection
+res.ehh<-calc_ehh(haplohh_cgu_bta12,mrk=456) 
+

The five different elements of the resulting object are as follows:

+
res.ehh$ehh[1:2,454:458]
+
>                   F1205380  F1205390 F1205400  F1205420  F1205440
+> Ancestral allele 0.2764706 0.5529412        1 0.8879552 0.6422969
+> Derived allele   1.0000000 1.0000000        1 1.0000000 1.0000000
+
res.ehh$nhaplo_eval[1:2,454:458]
+
>                  F1205380 F1205390 F1205400 F1205420 F1205440
+> Ancestral allele       85       85       85       85       85
+> Derived allele        195      195      195      195      195
+
res.ehh$freq_all1
+
> [1] 0.3035714
+
res.ehh$ihh
+
> Ancestral allele   Derived allele 
+>           284633          2057152
+In addition, as by default, we obtain the following plot (Figure ): +
+Graphical output for the \texttt{calc\_ehh()} function +

+Graphical output for the function +

+
+
+
+

The function

+

The function allows to compute the (both the \(\mathrm{EHHS}^{\text{Sab}}\) and \(\mathrm{EHHS}^{\text{Tang}}\) estimators) at the \(s^\text{th}\) SNP relative to each SNP (\(t\)) upstream and downstream. This function also compute the corresponding (\(\mathrm{iES}^{\text{Sab}}\) and \(\mathrm{iES}^{\text{Tang}}\) estimators respectively). The two options and allow to specify condition to stop computing (see ). By default =0.05 and =2. Finally, if , the decay of is plotted against SNP map position ( allows to change the plot legend). More details are available in the R documentation by using the command:

+
?calc_ehhs
+

In the following example, the statistics are computed for the \(456^{\text{th}}\) focal SNP on the object defined above (see ) was generated using the function with the example input files (see ) described above. For convenience, it is stored as an example object (accessible with the R function ).

+
#example haplohh object (280 haplotypes, 1424 SNPs) see ?haplohh_cgu_bta12 for details
+data(haplohh_cgu_bta12)
+#computing EHH statistics for the focal SNP at position 456
+#which display a strong signal of selection
+res.ehhs<-calc_ehhs(haplohh_cgu_bta12,mrk=456)
+

The five different elements of the resulting object are as follows:

+
res.ehhs$EHHS_Sabeti_et_al_2007[453:459] 
+
>  F1205370  F1205380  F1205390  F1205400  F1205420  F1205440  F1205450 
+> 0.5017153 0.5095238 0.5347926 1.0000000 0.5654122 0.5429595 0.5386841
+
res.ehhs$EHHS_Tang_et_al_2007[453:459] 
+
>  F1205370  F1205380  F1205390  F1205400  F1205420  F1205440  F1205450 
+> 0.8715588 0.8851234 0.9290193 1.0000000 0.9822104 0.9432066 0.9357794
+
res.ehhs$nhaplo_eval[453:459] 
+
> F1205370 F1205380 F1205390 F1205400 F1205420 F1205440 F1205450 
+>      280      280      280      280      280      280      280
+
res.ehhs$IES_Tang_et_al_2007
+
> [1] 1760565
+
res.ehhs$IES_Sabeti_et_al_2007
+
> [1] 964698
+In addition, as by default, we obtain the following plot (Figure ): +
+Graphical output for the \texttt{calc\_ehhs()} function +

+Graphical output for the function +

+
+
+
+

The function

+

The function allows to efficiently compute (for both the ancestral and derived alleles) and (both the \(\mathrm{iES}^{\text{Sab}}\) and \(\mathrm{iES}^{\text{Tang}}\) estimators) for all the SNPs in the object considered. The options , and specify conditions to stop computing and . By default ==0.05 and =2. Finally, the option , set by dafault to =1, allows to specify the number of available threads to parallelize computation (parallelization being carried out over SNPs). For instance to scan the object (containing data on 1424 SNPs for 280 haplotypes), one may use the following command:

+
data(haplohh_cgu_bta12)
+res.scan<-scan_hh(haplohh_cgu_bta12)
+

The resulting object is a data frame with (number of SNPs declared in the object) and seven columns giving for each SNP:

+
    +
  1. The SNP chromosome of origin
  2. +
  3. The SNP position
  4. +
  5. The SNP ancestral allele frequency
  6. +
  7. The estimated for the ancestral allele ()
  8. +
  9. The estimated for the derived allele ()
  10. +
  11. The estimated \(\mathrm{iES}^{\text{Tang}}\)
  12. +
  13. The estimated \(\mathrm{iES}^{\text{Sab}}\).
  14. +
+

As an example, the following R codes provide the dimension and the first five rows of the data frame obtained above:

+
dim(res.scan)
+
> [1] 1424    7
+
head(res.scan)
+
>          CHR POSITION    freq_A    iHH_A     iHH_D iES_Tang_et_al_2007
+> F1200140  12    79823 0.1500000 135102.2  68522.91            69776.85
+> F1200150  12   125974 0.4071429 161680.3 107183.15           123607.13
+> F1200170  12   175087 0.3571429 157333.1 155777.56           156021.90
+> F1200180  12   219152 0.2214286 250037.4 159839.73           166214.75
+> F1200190  12   256896 0.1750000 466071.8 173269.33           184453.42
+> F1200210  12   316254 0.3892857 292077.5 228681.21           246572.65
+>          iES_Sabeti_et_al_2007
+> F1200140              53669.39
+> F1200150              76287.51
+> F1200170              92770.96
+> F1200180             110712.37
+> F1200190             134092.34
+> F1200210             130156.22
+

Note that running is more efficient than running and in turn as shown in the example below (:.

+
system.time(res.scan<-scan_hh(haplohh_cgu_bta12))
+
>    user  system elapsed 
+>   0.260   0.000   0.257
+
foo<-function(haplo){
+res.ihh=res.ies=matrix(0,haplo@nsnp,2)
+for(i in 1:length(haplo@position)){
+  res.ihh[i,]=calc_ehh(haplo,mrk=i,plotehh=FALSE)$ihh
+  tmp=calc_ehhs(haplo,mrk=i,plotehhs=FALSE)
+  res.ies[i,1]=tmp$IES_Tang_et_al_2007
+  res.ies[i,2]=tmp$IES_Sabeti_et_al_2007  
+}
+list(res.ies=res.ies,res.ihh=res.ihh)
+}
+system.time(res.scan2<-foo(haplohh_cgu_bta12))
+
>    user  system elapsed 
+>  13.280   0.036  13.337
+

Note however that the same results are obtained (since the same options were used) as illustrated by the following R code:

+
sum(res.scan2$res.ihh[,1]!=res.scan[,4]) + sum(res.scan2$res.ihh[,2]!=res.scan[,5]) +
+sum(res.scan2$res.ies[,1]!=res.scan[,6]) + sum(res.scan2$res.ies[,2]!=res.scan[,7])
+
> [1] 0
+
+
+
+

Computing , and : the , and functions

+
+

Within population test: the

+
+

Definition

+

Let \(\mathrm{UniHS}\) represent the log-ratio of the for its ancestral (\(_a\)) and derived (\(_d\)) alleles: \[\mathrm{UniHS}=\log\left(\frac{\mathrm{iHH}_a}{\mathrm{iHH}_d}\right)\] The of a given focal SNP \(s\) (\(\mathrm{iHS}(s)\)) is then defined as its standardized \(\mathrm{UniHS}\) (\(\mathrm{UniHS}(s)\)) following (Voight et al. 2006): \[\mathrm{iHS}(s)=\frac{\mathrm{UniHS}(s) - \mu^{p_s}_\mathrm{UniHS}}{\sigma^{p_s}_\mathrm{UniHS}}\] where \(\mu^{p_s}_\mathrm{UniHS}\) and \(\sigma^{p_s}_\mathrm{UniHS}\) represent the average and standard deviation of the \(\mathrm{UniHS}\) computed over all the SNPs with a derived allele frequency \(p_s\) similar to that of the core SNP \(s\). In practice, the derived allele frequencies are generally binned so that each bin are large enough (e.g., >10 SNPs) to obtain reliable estimate of \(\mu^{p_s}_\mathrm{UniHS}\) and \(\sigma^{p_s}_\mathrm{UniHS}\).

+

Note that the is constructed to have an approximately standard Gaussian distribution and to be comparable across SNPs regardless of their underlying allele frequencies. Hence, one may further transform into \(p_\mathrm{iHS}\) (Gautier and Naves 2011): \[p_\mathrm{iHS}=-\log_{10}\left(1-2|\Phi\left(\mathrm{iHS}\right)-0.5|\right)\] where \(\Phi\left(x\right)\) represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical distribution is a fair approximation of the neutral distribution), \(p_\mathrm{iHS}\) might thus be interpreted as a two-sided P-value (on a \(-\log_{10}\) scale) associated to the neutral hypothesis of no selection.

+
+
+

The function

+

The function allows to compute using a matrix of statistics (for both the ancestral and derived alleles) in the same format as obtained from the function (see ). The argument allows to remove SNPs according to their MAF (by default SNPs with a MAF<=0.05 are discarded from the standardization). The argument controls the size of the allele frequency bins used to perform standardization (see ). More precisely allele frequency bins vary from to 1- per step of size (by default =0.025). Note that if is set to 0 (e.g., with a large number of SNPs and few haplotypes), standardization is performed considering each observed frequency as a frequency class.

+

For instance, to perform a whole genome scan one might run in turn on haplotype data from each chromosome and concatenate the resulting matrices before standardization. In the following example, we assume that the haplotype files are named as where the chromosome number \(i\) goes from 1 to 29 and the SNP information file is named . The R code below then generates a matrix with and estimates for all SNPs in an appropriate format to perform standardization with the function:

+
for(i in 1:29){
+ hap_file=paste("hap_chr_",i,".pop1",sep="")
+ data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i)
+ res<-scan_hh(data)
+ if(i==1){wg.res<-res}else{wg.res<-rbind(wg.res,res)}
+   }
+wg.ihs<-ihh2ihs(wg.res)
+

As a matter of illustration, results of a similar genome scan (Gautier and Naves 2011) are provided as example data sets. The following R code allows to compute the for the CGU population:

+
data(wgscan.cgu)
+## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details
+ihs.cgu<-ihh2ihs(wgscan.cgu)
+

The corresponding object is a list with two elements corresponding to

+
    +
  1. a matrix of SNP and the corresponding \(p_\mathrm{iHS}\) (P-values in a \(-\log_10\) scale assuming the are normally distributed under the neutral hypothesis). For instance, the five first rows of the data frame are displayed below using the following R command:
  2. +
+
head(ihs.cgu$iHS)
+
>          CHR POSITION        iHS -log10(p-value)
+> F0100190   1   113642 -0.5582992       0.2390952
+> F0100220   1   244699  0.2723337       0.1049282
+> F0100250   1   369419  0.4810736       0.2003396
+> F0100270   1   447278  1.0618710       0.5401640
+> F0100280   1   487654  0.8184060       0.3839181
+> F0100290   1   524507 -0.3897024       0.1569189
+

2.a matrix summarizing the allele frequency bins. For instance, the five first rows of the data frame are displayed below using the following R command:

+
head(ihs.cgu$frequency.class)
+
>              Number of SNPs mean of the log(iHHA/iHHD) ratio
+> 0.05 - 0.075           1635                        0.7286087
+> 0.075 - 0.1            1316                        0.5804760
+> 0.1 - 0.125            1478                        0.4710504
+> 0.125 - 0.15           1593                        0.3720585
+> 0.15 - 0.175           1078                        0.3263215
+> 0.175 - 0.2            1325                        0.2721166
+>              sd of the log(iHHA/iHHD) ratio
+> 0.05 - 0.075                      0.6457742
+> 0.075 - 0.1                       0.5556798
+> 0.1 - 0.125                       0.5079392
+> 0.125 - 0.15                      0.4708235
+> 0.15 - 0.175                      0.4524270
+> 0.175 - 0.2                       0.4533404
+
+
+

Manhattan plot of the results: the function

+

The function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the list object produced by the function . Various options are available to modify the graphical display (see ).

+
ihsplot(ihs.cgu,plot.pval=TRUE,ylim.scan=2,main="iHS (CGU cattle breed)") 
+
+Graphical output for the \texttt{ihsplot()} function +

+Graphical output for the function +

+
+
+
+
+

The –based pairwise population test

+
+

Definition

+

For a given SNP \(s\), let \[\mathrm{LRiES}(s)^{\text{Tang}}=\log\left(\frac{\mathrm{iES}_\text{pop1}(s)^{\text{Tang}}}{\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}}\right)\] represent the log-ratio of the \(\mathrm{iES}_\text{pop1}(s)^{\text{Tang}}\) and \(\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}\) computed in the pop1 and pop2 populations (see ).

+

The for a given focal SNP is then defined as the standardized \(\mathrm{LRiES}(s)^{\text{Tang}}\) (Tang et al. 2007):

+\begin{equation} +\mathrm{rSB}(s)=\frac{\mathrm{LRiES}(s)^{\text{Tang}} - \text{med}_{\mathrm{LRiES}^{\text{Tang}}}}{\sigma_{\mathrm{LRiES}^{\text{Tang}}}} +\end{equation} +

where \(\text{med}_{\mathrm{LRiES}^{\text{Tang}}}\) and \(\sigma_{\mathrm{LRiES}^{\text{Tang}}}\) represent the median and standard deviation of the \(\mathrm{LRiES}(s)^{\text{Tang}}\) computed over all the analyzed SNPs. Note that the median is used instead of the mean because it is less sensitive to extreme data points (Tang et al. 2007). More importantly, it should be noticed that the information about the ancestral and derived status of alleles at the focal SNP is not needed.

+As for the (see ), is constructed to have an approximately standard Gaussian distribution and may further be transformed into \(p_\mathrm{rSB}\): +\begin{equation} +p_\mathrm{rSB}=-\log_{10}\left(1-2|\Phi\left(\mathrm{rSB}\right)-0.5|\right) +\end{equation} +where \(\Phi\left(x\right)\) represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical distribution is a fair approximation of their corresponding neutral distributions), \(p_\mathrm{rSB}\) might thus be interpreted as a two-sided P-value (in a \(-\log_{10}\) scale) associated to the neutral hypothesis of no selection. Alternatively, \(p_\mathrm{rSB}\) might also be computed (Gautier and Naves 2011): +\begin{equation} +p\prime_\mathrm{rSB}=-\log_{10}\left(|\Phi\left(\mathrm{rSB}\right)|\right) +\end{equation} +

\(p\prime_\mathrm{rSB}\) and \(p\prime_\mathrm{rSB}\) might then be interpreted as a one-sided P-value (in a \(-\log_{10}\) scale) allowing the identification of those sites displaying a significantly high extended haplotype homozygosity in population \(pop2\) (represented in the denominator of the corresponding \(\mathrm{LRiES}\)) relatively to the \(pop1\) reference population.

+
+
+

The function

+

+

The function allows to compute using two data frames containing the statistics for each of the two populations considered in the same format as the one obtained after running the function (see ). For instance, to perform a genome scan one might first run for each population in turn on haplotype data from each chromosome and concatenate the resulting matrices. In the following example, we assume that the haplotype files are named as and where \(i\) is the chromosome number (going from 1 to 29), the suffixes pop1 and pop2 indicate the population of origin and the SNP information file is named . The R code below then generates two data frames ( and ) containing the results from all SNPs in the appropriate format to compute with the function:

+
for(i in 1:29){
+ hap_file=paste("hap_chr_",i,".pop1",sep="")
+ data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i)
+ res<-scan_hh(data)
+ if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)}
+ hap_file=paste("hap_chr_",i,".pop2",sep="")
+ data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i)
+ res<-scan_hh(data)
+ if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)}
+ }
+wg.rsb<-ies2rsb(wg.res.pop1,wg.res.pop2)
+

As a matter of illustration, one may consider results from a similar genome scan (Gautier and Naves 2011) provided as example data sets and compute for each SNP the between the CGU and EUT populations as follows:

+
data(wgscan.cgu) ; data(wgscan.eut)
+## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details
+cguVSeut.rsb<-ies2rsb(wgscan.cgu,wgscan.eut,"CGU","EUT")
+

The resulting object is a data frame with of SNP (and corresponding P-Values assuming are normally distributed under the neutral hypothesis). Note that either bilateral (default) or unilateral might be performed ( argument). The five first rows of the data frame are displayed below using the following R command:

+
head(cguVSeut.rsb)
+
>          CHR POSITION Rsb (CGU vs. EUT) -log10(p-value) [bilateral]
+> F0100190   1   113642        -0.3398574                  0.13432529
+> F0100220   1   244699        -1.0566283                  0.53658299
+> F0100250   1   369419        -0.1468326                  0.05390941
+> F0100270   1   447278        -1.8191608                  1.16186336
+> F0100280   1   487654        -0.2193069                  0.08280392
+> F0100290   1   524507        -0.7941300                  0.36945032
+
+
+

Manhattan plot of the results: the function

+

The function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the data frame produced by the function . Various options are available to modify the graphical display (see ). As an example, the Figure below provides the output of the function for the computed above across the CGU and EUT populations (see ). Figure was drawn using the following R code:

+
rsbplot(cguVSeut.rsb,plot.pval=TRUE)
+
+Graphical output for the \texttt{rsbplot()} function +

+Graphical output for the function +

+
+
+
+
+

The –based pairwise population test

+
+

Definition

+

The statistics (Sabeti et al. 2007) is similar to the except that it is based on the \(\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}\) (instead of \(\mathrm{iES}_\text{pop2}(s)^{\text{Tang}}\)) estimator of the (see ). Hence, for or a given SNP \(s\), let \[\mathrm{LRiES}(s)^{\text{Sab}}=\log\left(\frac{\mathrm{iES}_\text{pop1}(s)^{\text{Sab}}}{\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}}\right)\] represent the log-ratio of the \(\mathrm{iES}_\text{pop1}(s)^{\text{Sab}}\) and \(\mathrm{iES}_\text{pop2}(s)^{\text{Sab}}\) computed in the pop1 and pop2 populations (see ).

+

The for a given focal SNP is then defined as the standardized \(\mathrm{LRiES}(s)^{\text{Sab}}\) (Sabeti et al. 2007):

+\begin{equation} +\mathrm{rSB}(s)=\frac{\mathrm{LRiES}(s)^{\text{Sab}} - \text{med}_{\mathrm{LRiES}^{\text{Sab}}}}{\sigma_{\mathrm{LRiES}^{\text{Sab}}}} +\end{equation} +

where \(\text{med}_{\mathrm{LRiES}^{\text{Sab}}}\) and \(\sigma_{\mathrm{LRiES}^{\text{Sab}}}\) represent the median and standard deviation of the \(\mathrm{LRiES}(s)^{\text{Sab}}\) computed over all the analyzed SNPs. More importantly, it should be noticed that the information about the ancestral and derived status of alleles at the focal SNP is not needed.

+As for the (see ) and , is constructed to have an approximately standard Gaussian distribution and may further be transformed into \(p_\mathrm{xpEHH}\): +\begin{equation} +p_\mathrm{xpEHH}=-\log_{10}\left(1-2|\Phi\left(\mathrm{xpEHH}\right)-0.5|\right) +\end{equation} +where \(\Phi\left(x\right)\) represents the Gaussian cumulative distribution function. Assuming most of the genotyped SNPs behave neutrally (i.e., the genome-wide empirical distribution is a fair approximation of their corresponding neutral distributions), \(p_\mathrm{xpEHH}\) might thus be interpreted as a two-sided P-value (in a \(-\log_{10}\) scale) associated to the neutral hypothesis of no selection. Alternatively, \(p_\mathrm{xpEHH}\) might also be computed (Gautier and Naves 2011): +\begin{equation} +p\prime_\mathrm{xpEHH}=-\log_{10}\left(|\Phi\left(\mathrm{xpEHH}\right)|\right) +\end{equation} +

\(p\prime_\mathrm{xpEHH}\) and \(p\prime_\mathrm{xpEHH}\) might then be interpreted as a one-sided P-value (in a \(-\log_{10}\) scale) allowing the identification of those sites displaying a significantly high extended haplotype homozygosity in population \(pop2\) (represented in the denominator of the corresponding \(\mathrm{LRiES}\)) relatively to the \(pop1\) reference population.

+
+
+

The function

+

+

The function allows to compute using two data frames containing the statistics for each of the two populations considered in the same format as the one obtained after running the function (see ). For instance, to perform a genome scan one might first run for each population in turn on haplotype data from each chromosome and concatenate the resulting matrices. In the following example, we assume that the haplotype files are named as and where \(i\) is the chromosome number (going from 1 to 29), the suffixes pop1 and pop2 indicate the population of origin and the SNP information file is named . The R code below then generates two data frames ( and ) containing the results from all SNPs in the appropriate format to compute with the function:

+
for(i in 1:29){
+ hap_file=paste("hap_chr_",i,".pop1",sep="")
+ data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i)
+ res<-scan_hh(data)
+ if(i==1){wg.res.pop1<-res}else{wg.res.pop1<-rbind(wg.res.pop1,res)}
+ hap_file=paste("hap_chr_",i,".pop2",sep="")
+ data<-data2haplohh(hap_file="hap_file","snp.info",chr.name=i)
+ res<-scan_hh(data)
+ if(i==1){wg.res.pop2<-res}else{wg.res.pop2<-rbind(wg.res.pop2,res)}
+ }
+wg.xpehh<-ies2xpehh(wg.res.pop1,wg.res.pop2)
+

As a matter of illustration, one may consider results from a similar genome scan (Gautier and Naves 2011) provided as example data sets and compute for each SNP the between the CGU and EUT populations as follows:

+
data(wgscan.cgu) ; data(wgscan.eut)
+## results from a genome scan (44,057 SNPs) see ?wgscan.eut and ?wgscan.cgu for details
+cguVSeut.xpehh<-ies2xpehh(wgscan.cgu,wgscan.eut,"CGU","EUT")
+

The resulting object is a data frame with of SNP (and corresponding P-values assuming are normally distributed under the neutral hypothesis). Note that either bilateral (default) or unilateral might be performed ( argument). The five first rows of this data frame are displayed below using the following R command:

+
head(cguVSeut.xpehh)
+
>          CHR POSITION XPEHH (CGU vs. EUT) -log10(p-value) [bilateral]
+> F0100190   1   113642          -0.5555841                   0.2377002
+> F0100220   1   244699          -0.7516166                   0.3445910
+> F0100250   1   369419          -0.8885736                   0.4268588
+> F0100270   1   447278          -0.3470522                   0.1375394
+> F0100280   1   487654          -0.9182772                   0.4455426
+> F0100290   1   524507          -0.7521031                   0.3448721
+
+
+

Manhattan plot of the results: the function

+

The function allows to draw a Manhattan plot of the Whole Genome scan results as stored in the data frame produced by the function . Various options are available to modify the graphical display (see ). As an example, the Figure below provides the output of the function for the computed above across the CGU and EUT populations (see ). Figure was drawn using the following R code:

+
xpehhplot(cguVSeut.xpehh,plot.pval=TRUE)
+
+Graphical output for the \texttt{xpehhplot()} function +

+Graphical output for the function +

+
+
+
+

vs. comparison:

+

A plot of the against estimates across the CGU and EUT populations (see and respectively) is represented in the Figure below. This figure was generated using the following R code:

+
plot(cguVSeut.rsb[,3],cguVSeut.xpehh[,3],xlab="Rsb",ylab="XPEHH",pch=16,
+    cex=0.5,cex.lab=0.75,cex.axis=0.75)
+abline(a=0,b=1,lty=2)
+
+Comparison of the XPEHH and Rsb estimates across the CGU and EUT populations +

+Comparison of the XPEHH and Rsb estimates across the CGU and EUT populations +

+
+
+
+
+

Visual inspection of the standardized scores distribution: the function

+

The function allows to easily visualize the distributions of the standardized scores (either , or ) and compare them to the standard Gaussian distribution. As an example, the Figure below provides the output the function when considering the estimates obtained for the CGU population (see ) using the following R code:

+
distribplot(ihs.cgu$iHS[,3],xlab="iHS")
+
+Graphical output for the function \texttt{distribplot} +

+Graphical output for the function +

+
+
+
+
+

Visualizing haplotype structure around a core allele: the function

+

The function function draws haplotype bifurcation diagrams (Sabeti et al. 2002) that allow to better understand the origin of an observed footprints of selection. Such diagrams indeed consist in plotting the breakdown of LD at increasing distances from the core allele at the selected focal SNPs. The root (focal SNP) of each diagram is the core allele and is here identified by a vertical dashed line. The diagram is bi-directional, portraying both centromere-proximal and centromere-distal LD. Moving in one direction, each marker is an opportunity for a node; the diagram either divides or not based on whether both or only one allele is present. Thus the breakdown of LD on the core haplotype background is portrayed at progressively longer distances. The thickness of the lines corresponds to the number of samples with the indicated long-distance haplotype. Several options are available to modify the aspect of the plots (see command ) As a matter of illustration, Figure shows the bifurcation diagrams for both the derived and ancestral alleles at the \(456^{\text{th}}\) SNP on BTA12 CGU haplotypes. This SNP displayed a strong signal of selection (using both and statistics) and is located closed (<5kb) to a strong candidate genes involved in horn development (Gautier and Naves 2011). Figure was obtained with the following R code:

+
data(haplohh_cgu_bta12)
+layout(matrix(1:2,2,1))
+bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=1,nmrk_l=20,nmrk_r=20,
+                    main="Bifurcation diagram (RXFP2 SNP on BTA12): Ancestral Allele")
+bifurcation.diagram(haplohh_cgu_bta12,mrk_foc=456,all_foc=2,nmrk_l=20,nmrk_r=20,
+                    main="Bifurcation diagram (RXFP2 SNP on BTA12): Derived Allele")
+
+Graphical output for the function \texttt{bifurcation.diagram()} +

+Graphical output for the function +

+
+

+
+
+

References

+
+
+

Gautier M., Naves M., 2011 Footprints of selection in the ancestral admixture of a New World Creole cattle breed. Mol Ecol 20: 3128–3143.

+
+
+

O’Connell J., Gurdasani D., Delaneau O., Pirastu N., Ulivi S., others, 2014 A general approach for haplotype phasing across the full spectrum of relatedness. PLoS Genet 10: e1004234.

+
+
+

Sabeti P. C., Reich D. E., Higgins J. M., Levine H. Z. P., Richter D. J., others, 2002 Detecting recent positive selection in the human genome from haplotype structure. Nature 419: 832–837.

+
+
+

Sabeti P. C., Varilly P., Fry B., Lohmueller J., Hostetter E., others, 2007 Genome-wide detection and characterization of positive selection in human populations. Nature 449: 913–918.

+
+
+

Scheet P., Stephens M., 2006 A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet 78: 629–644.

+
+
+

Tang K., Thornton K. R., Stoneking M., 2007 A new approach for using genome scans to detect recent positive selection in the human genome. PLoS Biol 5: e171.

+
+
+

Voight B. F., Kudaravalli S., Wen X., Pritchard J. K., 2006 A map of recent positive selection in the human genome. PLoS Biol 4: e72.

+
+
+
+ + + + +
+ + + + + + + + diff --git a/vignettes/vignette.bib b/vignettes/vignette.bib new file mode 100644 index 0000000..fac53ff --- /dev/null +++ b/vignettes/vignette.bib @@ -0,0 +1,323 @@ +% This file was created with JabRef 2.10. +% Encoding: UTF-8 + + +@Article{Baird2008, + Title = {Rapid SNP discovery and genetic mapping using sequenced RAD markers.}, + Author = {Nathan A Baird and Paul D Etter and Tressa S Atwood and Mark C Currey and Anthony L Shiver and Zachary A Lewis and Eric U Selker and William A Cresko and Eric A Johnson}, + Journal = {PLoS One}, + Year = {2008}, + Number = {10}, + Pages = {e3376}, + Volume = {3}, + + Abstract = {Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery and genotyping in large populations. Here we describe the sequencing of restriction-site associated DNA (RAD) tags, which identified more than 13,000 SNPs, and mapped three traits in two model organisms, using less than half the capacity of one Illumina sequencing run. We demonstrated that different marker densities can be attained by choice of restriction enzyme. Furthermore, we developed a barcoding system for sample multiplexing and fine mapped the genetic basis of lateral plate armor loss in threespine stickleback by identifying recombinant breakpoints in F(2) individuals. Barcoding also facilitated mapping of a second trait, a reduction of pelvic structure, by in silico re-sorting of individuals. To further demonstrate the ease of the RAD sequencing approach we identified polymorphic markers and mapped an induced mutation in Neurospora crassa. Sequencing of RAD markers is an integrated platform for SNP discovery and genotyping. This approach should be widely applicable to genetic mapping in a variety of organisms.}, + Doi = {10.1371/journal.pone.0003376}, + Institution = {Institute of Molecular Biology, University of Oregon, Eugene, Oregon, United States of America.}, + Keywords = {Animals; Chromosome Mapping, methods; Expressed Sequence Tags; Genetic Markers; Genome; Genotype; Methods; Neurospora crassa, genetics; Polymorphism, Single Nucleotide; Restriction Mapping; Smegmamorpha, genetics}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pmid = {18852878}, + Timestamp = {2011.11.24}, + Url = {http://dx.doi.org/10.1371/journal.pone.0003376} +} + +@Article{Gautier2011, + Title = {Footprints of selection in the ancestral admixture of a New World Creole cattle breed.}, + Author = {Mathieu Gautier and Michel Naves}, + Journal = {Mol Ecol}, + Year = {2011}, + + Month = {Aug}, + Number = {15}, + Pages = {3128--3143}, + Volume = {20}, + + Abstract = {Admixed populations represent attractive biological models to study adaptive selection. Originating from several waves of recent introduction from European (EUT), African (AFT) and zebus (ZEB) cattle, New World Creole cattle allow investigating the response to tropical environmental challenges of these three ancestries. We here provide a detailed assessment of their genetic contributions to the Creole breed from Guadeloupe (CGU). We subsequently look for footprints of selection by combining results from tests based on the extent of haplotype homozygosity and the identification of excess/deficiency of local ancestry. To tackle these issues, 140 CGU individuals and 25 Brahman zebus from Martinique were genotyped at 44 057 SNPs. These data were combined to those available on 23 populations representative of EUT, AFT or ZEB. We found average proportions of 26.1\%, 36.0\% and 37.9\% of EUT, AFT and ZEB ancestries in the CGU genome indicating a higher level of African and zebu ancestries than suggested by historical records. We further identified 23 genomic regions displaying strong signal of selection, most of them being characterized by an excess of ZEB local ancestry. Among the candidate gene underlying these regions, several are associated with reproductive functions (RXFP2, PMEPA1, IGFBP3, KDR, PPP1R8, TBXA2R and SLC7A5) and metabolism (PDE1B and CYP46A1). Finally, two genes (CENTD3 and SAMD12) are involved in cellular signalization of immune response. This study illustrates the relevance of admixed populations to identify footprints of selection by combining several tests straightforward to implement on large data sets.}, + Doi = {10.1111/j.1365-294X.2011.05163.x}, + Institution = {INRA, UMR CBGP (INRA/CIRAD/IRD/Supagro), Montferrier-sur-Lez, France. Mathieu.Gautier@supagro.inra.fr}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pmid = {21689193}, + Timestamp = {2011.12.01}, + Url = {http://dx.doi.org/10.1111/j.1365-294X.2011.05163.x} +} + +@Article{Gautier2012, + Title = {rehh: an R package to detect footprints of selection in genome-wide SNP data from haplotype structure.}, + Author = {Mathieu Gautier and Renaud Vitalis}, + Journal = {Bioinformatics}, + Year = {2012}, + + Month = {Apr}, + Number = {8}, + Pages = {1176--1177}, + Volume = {28}, + Abstract = {With the development of next-generation sequencing and genotyping approaches, large single nucleotide polymorphism haplotype datasets are becoming available in a growing number of both model and non-model species. Identifying genomic regions with unexpectedly high local haplotype homozygosity relatively to neutral expectation represents a powerful strategy to ascertain candidate genes responding to natural or artificial selection. To facilitate genome-wide scans of selection based on the analysis of long-range haplotypes, we developed the R package rehh. It provides a versatile tool to detect the footprints of recent or ongoing selection with several graphical functions that help visual interpretation of the results.Stable version is available from CRAN: http://cran.r-project.org/. Development version is available from the R-forge repository: http://r-forge.r-project.org/projects/rehh. Both versions can be installed directly from R. Function documentation and example data files are provided within the package and a tutorial is available as Supplementary Material. rehh is distributed under the GNU General Public Licence (GPL ≥ 2).}, + Doi = {10.1093/bioinformatics/bts115}, + Institution = {INRA, Montferrier-sur-Lez Cedex, France. mathieu.gautier@supagro.inra.fr}, + Keywords = {Animals; Cattle; Genome-Wide Association Study; Haplotypes; Polymorphism, Single Nucleotide; Software}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {bts115}, + Pmid = {22402612}, + Timestamp = {2016.05.04}, + Url = {http://dx.doi.org/10.1093/bioinformatics/bts115} +} + +@Article{Maclean2015, + Title = {hapbin: An Efficient Program for Performing Haplotype-Based Scans for Positive Selection in Large Genomic Datasets.}, + Author = {Colin A Maclean and Neil P Chue Hong and James G D Prendergast}, + Journal = {Mol Biol Evol}, + Year = {2015}, + + Month = {Nov}, + Number = {11}, + Pages = {3027--3029}, + Volume = {32}, + Abstract = {Understanding how the genome is shaped by selective processes forms an integral part of modern biology. However, as genomic datasets continue to grow larger it is becoming increasingly difficult to apply traditional statistics for detecting signatures of selection to these cohorts. There is therefore a pressing need for the development of the next generation of computational and analytical tools for detecting signatures of selection in large genomic datasets. Here, we present hapbin, an efficient multithreaded implementation of extended haplotype homzygosity-based statistics for detecting selection, which is up to 3,400 times faster than the current fastest implementations of these algorithms.}, + Doi = {10.1093/molbev/msv172}, + Institution = {Roslin Institute, University of Edinburgh, Scotland, United Kingdom prenderj@gmail.com.}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {msv172}, + Pmid = {26248562}, + Timestamp = {2016.05.04}, + Url = {http://dx.doi.org/10.1093/molbev/msv172} +} + +@Article{McVean2007, + Title = {The structure of linkage disequilibrium around a selective sweep.}, + Author = {Gil McVean}, + Journal = {Genetics}, + Year = {2007}, + + Month = {Mar}, + Number = {3}, + Pages = {1395--1406}, + Volume = {175}, + + Abstract = {The fixation of advantageous mutations by natural selection has a profound impact on patterns of linked neutral variation. While it has long been appreciated that such selective sweeps influence the frequency spectrum of nearby polymorphism, it has only recently become clear that they also have dramatic effects on local linkage disequilibrium. By extending previous results on the relationship between genealogical structure and linkage disequilibrium, I obtain simple expressions for the influence of a selective sweep on patterns of allelic association. I show that sweeps can increase, decrease, or even eliminate linkage disequilibrium (LD) entirely depending on the relative position of the selected and neutral loci. I also show the importance of the age of the neutral mutations in predicting their degree of association and describe the consequences of such results for the interpretation of empirical data. In particular, I demonstrate that while selective sweeps can eliminate LD, they generate patterns of genetic variation very different from those expected from recombination hotspots.}, + Doi = {10.1534/genetics.106.062828}, + Institution = {c.uk}, + Keywords = {Alleles; Computer Simulation; Genetic Variation; Linkage Disequilibrium, genetics; Models, Genetic; Mutation, genetics; Selection, Genetic}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {genetics.106.062828}, + Pmid = {17194788}, + Timestamp = {2011.12.05}, + Url = {http://dx.doi.org/10.1534/genetics.106.062828} +} + +@Article{OConnell2014, + Title = {A general approach for haplotype phasing across the full spectrum of relatedness.}, + Author = {O'Connell, Jared and Gurdasani, Deepti and Delaneau, Olivier and Pirastu, Nicola and Ulivi, Sheila and others}, + Journal = {PLoS Genet}, + Year = {2014}, + + Month = {Apr}, + Number = {4}, + Pages = {e1004234}, + Volume = {10}, + + __markedentry = {[mathieu:6]}, + Abstract = {Many existing cohorts contain a range of relatedness between genotyped individuals, either by design or by chance. Haplotype estimation in such cohorts is a central step in many downstream analyses. Using genotypes from six cohorts from isolated populations and two cohorts from non-isolated populations, we have investigated the performance of different phasing methods designed for nominally 'unrelated' individuals. We find that SHAPEIT2 produces much lower switch error rates in all cohorts compared to other methods, including those designed specifically for isolated populations. In particular, when large amounts of IBD sharing is present, SHAPEIT2 infers close to perfect haplotypes. Based on these results we have developed a general strategy for phasing cohorts with any level of implicit or explicit relatedness between individuals. First SHAPEIT2 is run ignoring all explicit family information. We then apply a novel HMM method (duoHMM) to combine the SHAPEIT2 haplotypes with any family information to infer the inheritance pattern of each meiosis at all sites across each chromosome. This allows the correction of switch errors, detection of recombination events and genotyping errors. We show that the method detects numbers of recombination events that align very well with expectations based on genetic maps, and that it infers far fewer spurious recombination events than Merlin. The method can also detect genotyping errors and infer recombination events in otherwise uninformative families, such as trios and duos. The detected recombination events can be used in association scans for recombination phenotypes. The method provides a simple and unified approach to haplotype estimation, that will be of interest to researchers in the fields of human, animal and plant genetics.}, + Doi = {10.1371/journal.pgen.1004234}, + Institution = {Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; Department of Statistics, University of Oxford, Oxford, United Kingdom.}, + Keywords = {Chromosome Mapping, methods; Cohort Effect; Family; Genotype; Haplotypes, genetics; Humans; Models, Genetic; Pedigree; Phenotype; Recombination, Genetic, genetics}, + Language = {eng}, + Medline-pst = {epublish}, + Owner = {mathieu}, + Pii = {PGENETICS-D-13-01268}, + Pmid = {24743097}, + Timestamp = {2016.05.06}, + Url = {http://dx.doi.org/10.1371/journal.pgen.1004234} +} + +@Manual{Rkey, + Title = {R: A Language and Environment for Statistical Computing}, + + Address = {Vienna, Austria}, + Author = {{R Development Core Team}}, + Note = {{ISBN} 3-900051-07-0}, + Organization = {R Foundation for Statistical Computing}, + Year = {2008}, + + Owner = {mathieu}, + Timestamp = {2011.12.01}, + Url = {http://www.R-project.org} +} + +@Article{Sabeti2002, + Title = {Detecting recent positive selection in the human genome from haplotype structure.}, + Author = {Pardis C Sabeti and David E Reich and John M Higgins and Haninah Z P Levine and Daniel J Richter and others}, + Journal = {Nature}, + Year = {2002}, + + Month = {Oct}, + Number = {6909}, + Pages = {832--837}, + Volume = {419}, + + Abstract = {The ability to detect recent natural selection in the human population would have profound implications for the study of human history and for medicine. Here, we introduce a framework for detecting the genetic imprint of recent positive selection by analysing long-range haplotypes in human populations. We first identify haplotypes at a locus of interest (core haplotypes). We then assess the age of each core haplotype by the decay of its association to alleles at various distances from the locus, as measured by extended haplotype homozygosity (EHH). Core haplotypes that have unusually high EHH and a high population frequency indicate the presence of a mutation that rose to prominence in the human gene pool faster than expected under neutral evolution. We applied this approach to investigate selection at two genes carrying common variants implicated in resistance to malaria: G6PD and CD40 ligand. At both loci, the core haplotypes carrying the proposed protective mutation stand out and show significant evidence of selection. More generally, the method could be used to scan the entire genome for evidence of recent positive selection.}, + Doi = {10.1038/nature01140}, + Institution = {Whitehead Institute/MIT Center for Genome Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA.}, + Keywords = {Africa; Alleles; Animals; CD40 Ligand, genetics; Computer Simulation; Evolution, Molecular; Gene Pool; Genetic Predisposition to Disease, genetics; Genetic Variation, genetics; Genome, Human; Glucosephosphate Dehydrogenase, genetics; Haplotypes, genetics; Homozygote; Humans; Malaria, enzymology/genetics/parasitology; Male; Mutation, genetics; Plasmodium falciparum, physiology; Polymorphism, Single Nucleotide, genetics; Selection, Genetic; Time Factors}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {nature01140}, + Pmid = {12397357}, + Timestamp = {2011.12.01}, + Url = {http://dx.doi.org/10.1038/nature01140} +} + +@Article{Sabeti2007, + Title = {Genome-wide detection and characterization of positive selection in human populations.}, + Author = {Pardis C Sabeti and Patrick Varilly and Ben Fry and Jason Lohmueller and Elizabeth Hostetter and others}, + Journal = {Nature}, + Year = {2007}, + + Month = {Oct}, + Number = {7164}, + Pages = {913--918}, + Volume = {449}, + + Abstract = {With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and we also developed new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population. The analysis reveals more than 300 strong candidate regions. Focusing on the strongest 22 regions, we develop a heuristic for scrutinizing these regions to identify candidate targets of selection. In a complementary analysis, we identify 26 non-synonymous, coding, single nucleotide polymorphisms showing regional evidence of positive selection. Examination of these candidates highlights three cases in which two genes in a common biological process have apparently undergone positive selection in the same population:LARGE and DMD, both related to infection by the Lassa virus, in West Africa;SLC24A5 and SLC45A2, both involved in skin pigmentation, in Europe; and EDAR and EDA2R, both involved in development of hair follicles, in Asia.}, + Doi = {10.1038/nature06250}, + Institution = {Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA. pardis@broad.mit.edu}, + Keywords = {Antiporters, genetics; Edar Receptor, chemistry/genetics; Gene Frequency; Genetics, Population; Genome, Human, genetics; Geography; Haplotypes, genetics; Humans; Models, Molecular; Polymorphism, Single Nucleotide, genetics; Protein Structure, Tertiary; Selection, Genetic}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {nature06250}, + Pmid = {17943131}, + Timestamp = {2016.05.04}, + Url = {http://dx.doi.org/10.1038/nature06250} +} + +@Article{Scheet2006, + Title = {A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.}, + Author = {Scheet, Paul and Stephens, Matthew}, + Journal = {Am J Hum Genet}, + Year = {2006}, + + Month = {Apr}, + Number = {4}, + Pages = {629--644}, + Volume = {78}, + + __markedentry = {[mathieu:]}, + Abstract = {We present a statistical model for patterns of genetic variation in samples of unrelated individuals from natural populations. This model is based on the idea that, over short regions, haplotypes in a population tend to cluster into groups of similar haplotypes. To capture the fact that, because of recombination, this clustering tends to be local in nature, our model allows cluster memberships to change continuously along the chromosome according to a hidden Markov model. This approach is flexible, allowing for both "block-like" patterns of linkage disequilibrium (LD) and gradual decline in LD with distance. The resulting model is also fast and, as a result, is practicable for large data sets (e.g., thousands of individuals typed at hundreds of thousands of markers). We illustrate the utility of the model by applying it to dense single-nucleotide-polymorphism genotype data for the tasks of imputing missing genotypes and estimating haplotypic phase. For imputing missing genotypes, methods based on this model are as accurate or more accurate than existing methods. For haplotype estimation, the point estimates are slightly less accurate than those from the best existing methods (e.g., for unrelated Centre d'Etude du Polymorphisme Humain individuals from the HapMap project, switch error was 0.055 for our method vs. 0.051 for PHASE) but require a small fraction of the computational cost. In addition, we demonstrate that the model accurately reflects uncertainty in its estimates, in that probabilities computed using the model are approximately well calibrated. The methods described in this article are implemented in a software package, fastPHASE, which is available from the Stephens Lab Web site.}, + Doi = {10.1086/502802}, + Institution = {Department of Statistics, University of Washington, Seattle, 98195-4322, USA. pscheet@alum.wustl.edu}, + Keywords = {Calibration; Genetics, Population; Genotype; Haplotypes; Humans; Models, Statistical; Probability}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {S0002-9297(07)63701-X}, + Pmid = {16532393}, + Timestamp = {2016.05.06}, + Url = {http://dx.doi.org/10.1086/502802} +} + +@Article{smith_hitch-hiking_1974, + Title = {The {Hitch-Hiking} Effect of a Favourable Gene}, + Author = {Smith, John Maynard and Haigh, John}, + Journal = {Genetics Research}, + Year = {1974}, + Number = {01}, + Pages = {23--35}, + Volume = {23}, + + Doi = {10.1017/S0016672300014634}, + Owner = {mathieu}, + Timestamp = {2011.12.06}, + Url = {http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=1754360} +} + +@Article{Szpiech2014, + Title = {selscan: an efficient multithreaded program to perform EHH-based scans for positive selection.}, + Author = {Zachary A Szpiech and Ryan D Hernandez}, + Journal = {Mol Biol Evol}, + Year = {2014}, + + Month = {Oct}, + Number = {10}, + Pages = {2824--2827}, + Volume = {31}, + + Abstract = {Haplotype-based scans to detect natural selection are useful to identify recent or ongoing positive selection in genomes. As both real and simulated genomic data sets grow larger, spanning thousands of samples and millions of markers, there is a need for a fast and efficient implementation of these scans for general use. Here, we present selscan, an efficient multithreaded application that implements Extended Haplotype Homozygosity (EHH), Integrated Haplotype Score (iHS), and Cross-population EHH (XPEHH). selscan accepts phased genotypes in multiple formats, including TPED, and performs extremely well on both simulated and real data and over an order of magnitude faster than existing available implementations. It calculates iHS on chromosome 22 (22,147 loci) across 204 CEU haplotypes in 353 s on one thread (33 s on 16 threads) and calculates XPEHH for the same data relative to 210 YRI haplotypes in 578 s on one thread (52 s on 16 threads). Source code and binaries (Windows, OSX, and Linux) are available at https://github.com/szpiech/selscan.}, + Doi = {10.1093/molbev/msu211}, + Institution = {Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco Institute for Human Genetics, University of California, San Francisco Institute for Quantitative Biosciences (QB3), University of California, San Francisco.}, + Keywords = {Algorithms; Chromosomes, Human, Pair 22, genetics; Genome; Haplotypes; Humans; Selection, Genetic; Software}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {msu211}, + Pmid = {25015648}, + Timestamp = {2016.05.04}, + Url = {http://dx.doi.org/10.1093/molbev/msu211} +} + +@Article{Tang2007, + Title = {A new approach for using genome scans to detect recent positive selection in the human genome.}, + Author = {Kun Tang and Kevin R Thornton and Mark Stoneking}, + Journal = {PLoS Biol}, + Year = {2007}, + + Month = {Jul}, + Number = {7}, + Pages = {e171}, + Volume = {5}, + + Abstract = {Genome-wide scanning for signals of recent positive selection is essential for a comprehensive and systematic understanding of human adaptation. Here, we present a genomic survey of recent local selective sweeps, especially aimed at those nearly or recently completed. A novel approach was developed for such signals, based on contrasting the extended haplotype homozygosity (EHH) profiles between populations. We applied this method to the genome single nucleotide polymorphism (SNP) data of both the International HapMap Project and Perlegen Sciences, and detected widespread signals of recent local selection across the genome, consisting of both complete and partial sweeps. A challenging problem of genomic scans of recent positive selection is to clearly distinguish selection from neutral effects, given the high sensitivity of the test statistics to departures from neutral demographic assumptions and the lack of a single, accurate neutral model of human history. We therefore developed a new procedure that is robust across a wide range of demographic and ascertainment models, one that indicates that certain portions of the genome clearly depart from neutrality. Simulations of positive selection showed that our tests have high power towards strong selection sweeps that have undergone fixation. Gene ontology analysis of the candidate regions revealed several new functional groups that might help explain some important interpopulation differences in phenotypic traits.}, + Doi = {10.1371/journal.pbio.0050171}, + Institution = {Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. tang@eva.mpg.de}, + Keywords = {Alleles; Biometry; Databases, Genetic; Genetic Techniques; Genetics, Population; Genome, Human; Haplotypes; Humans; Models, Genetic; Polymorphism, Single Nucleotide; Recombination, Genetic; Selection, Genetic; Time Factors}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {06-PLBI-RA-1819}, + Pmid = {17579516}, + Timestamp = {2011.12.01}, + Url = {http://dx.doi.org/10.1371/journal.pbio.0050171} +} + +@Article{Voight2006, + Title = {A map of recent positive selection in the human genome.}, + Author = {Benjamin F Voight and Sridhar Kudaravalli and Xiaoquan Wen and Jonathan K Pritchard}, + Journal = {PLoS Biol}, + Year = {2006}, + + Month = {Mar}, + Number = {3}, + Pages = {e72}, + Volume = {4}, + + Abstract = {The identification of signals of very recent positive selection provides information about the adaptation of modern humans to local conditions. We report here on a genome-wide scan for signals of very recent positive selection in favor of variants that have not yet reached fixation. We describe a new analytical method for scanning single nucleotide polymorphism (SNP) data for signals of recent selection, and apply this to data from the International HapMap Project. In all three continental groups we find widespread signals of recent positive selection. Most signals are region-specific, though a significant excess are shared across groups. Contrary to some earlier low resolution studies that suggested a paucity of recent selection in sub-Saharan Africans, we find that by some measures our strongest signals of selection are from the Yoruba population. Finally, since these signals indicate the existence of genetic variants that have substantially different fitnesses, they must indicate loci that are the source of significant phenotypic variation. Though the relevant phenotypes are generally not known, such loci should be of particular interest in mapping studies of complex traits. For this purpose we have developed a set of SNPs that can be used to tag the strongest approximately 250 signals of recent selection in each population.}, + Doi = {10.1371/journal.pbio.0040072}, + Institution = {Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.}, + Keywords = {Alleles; Chromosomes, Human, genetics; Genome, Human, genetics; Humans; Physical Chromosome Mapping; Polymorphism, Single Nucleotide, genetics; Selection, Genetic}, + Language = {eng}, + Medline-pst = {ppublish}, + Owner = {mathieu}, + Pii = {05-PLBI-RA-1239R2}, + Pmid = {16494531}, + Timestamp = {2011.12.01}, + Url = {http://dx.doi.org/10.1371/journal.pbio.0040072} +} + +@comment{jabref-meta: selector_publisher:} + +@comment{jabref-meta: selector_author:} + +@comment{jabref-meta: selector_journal:} + +@comment{jabref-meta: selector_keywords:} +