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DESCRIPTION
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Type: Package
Package: nlmixr2est
Title: Nonlinear Mixed Effects Models in Population PK/PD, Estimation
Routines
Version: 3.0.3
Authors@R: c(
person("Matthew", "Fidler", , "[email protected]", role = c("aut", "cre"),
comment = c(ORCID = "0000-0001-8538-6691")),
person("Yuan", "Xiong", , "[email protected]", role = "aut"),
person("Rik", "Schoemaker", , "[email protected]", role = "aut",
comment = c(ORCID = "0000-0002-7538-3005")),
person("Justin", "Wilkins", , "[email protected]", role = "aut",
comment = c(ORCID = "0000-0002-7099-9396")),
person("Wenping", "Wang", , "[email protected]", role = "aut"),
person("Robert", "Leary", role = "ctb"),
person("Mason", "McComb", , "[email protected]", role = "ctb",
comment = c(ORCID = "0000-0001-9871-8616")),
person("Vipul", "Mann", , "[email protected]", role = "aut"),
person("Mirjam", "Trame", , "[email protected]", role = "ctb"),
person("Mahmoud", "Abdelwahab", , "[email protected]", role = "ctb"),
person("Teun", "Post", , "[email protected]", role = "ctb"),
person("Richard", "Hooijmaijers", , "[email protected]", role = "aut"),
person("Hadley", "Wickham", role = "ctb"),
person("Dirk", "Eddelbuettel", , "[email protected]", role = "cph"),
person("Johannes", "Pfeifer", role = "ctb"),
person("Robert B.", "Schnabel", role = "ctb"),
person("Elizabeth", "Eskow", role = "ctb"),
person("Emmanuelle", "Comets", , "[email protected]", role = "ctb"),
person("Audrey", "Lavenu", role = "ctb"),
person("Marc", "Lavielle", role = "ctb"),
person("David", "Ardia", role = "cph"),
person("Katharine", "Mullen", role = "cph"),
person("Ben", "Goodrich", role = "ctb")
)
Maintainer: Matthew Fidler <[email protected]>
Description: Fit and compare nonlinear mixed-effects models in
differential equations with flexible dosing information commonly seen
in pharmacokinetics and pharmacodynamics (Almquist, Leander, and
Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation
solving is by compiled C code provided in the 'rxode2' package (Wang,
Hallow, and James 2015 <doi:10.1002/psp4.12052>).
License: GPL (>= 3)
URL: https://github.com/nlmixr2/nlmixr2est,
https://nlmixr2.github.io/nlmixr2est/
Depends: nlmixr2data, R (>= 4.0)
Imports: backports, checkmate, cli, graphics, knitr, lbfgsb3c, lotri,
magrittr, Matrix, methods, minqa, n1qn1 (>= 6.0.1-12), nlme,
Rcpp, rex, rxode2 (>= 3.0.0), stats, symengine, utils
Suggests: broom.mixed, crayon, data.table, devtools, digest, dplyr (>=
1.1.0), generics, nloptr, qs, sys, testthat, tibble, withr,
xgxr, sfsmisc, minpack.lm, remotes
LinkingTo: BH, n1qn1 (>= 6.0.1-12), lbfgsb3c (>= 2024-3.5), lotri (>=
0.5.0), Rcpp, RcppArmadillo (>= 0.11.2.3.1), RcppEigen, rxode2
(>= 3.0.0)
Biarch: true
Config/testthat/edition: 3
Encoding: UTF-8
Language: en-US
NeedsCompilation: yes
RoxygenNote: 7.3.2
LazyData: true
Packaged: 2025-01-18 17:02:04 UTC; matt
Author: Matthew Fidler [aut, cre] (<https://orcid.org/0000-0001-8538-6691>),
Yuan Xiong [aut],
Rik Schoemaker [aut] (<https://orcid.org/0000-0002-7538-3005>),
Justin Wilkins [aut] (<https://orcid.org/0000-0002-7099-9396>),
Wenping Wang [aut],
Robert Leary [ctb],
Mason McComb [ctb] (<https://orcid.org/0000-0001-9871-8616>),
Vipul Mann [aut],
Mirjam Trame [ctb],
Mahmoud Abdelwahab [ctb],
Teun Post [ctb],
Richard Hooijmaijers [aut],
Hadley Wickham [ctb],
Dirk Eddelbuettel [cph],
Johannes Pfeifer [ctb],
Robert B. Schnabel [ctb],
Elizabeth Eskow [ctb],
Emmanuelle Comets [ctb],
Audrey Lavenu [ctb],
Marc Lavielle [ctb],
David Ardia [cph],
Katharine Mullen [cph],
Ben Goodrich [ctb]
Repository: CRAN
Date/Publication: 2025-01-18 17:50:02 UTC