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Hello, I have a question regarding the application of ftINIT to construct GEMs from integrated scRNA-seq data.
As far as I understand, UMI counts of single-cell bootstraps are pooled and converted to CPM before ftINIT can be used to construct bootstrap-specific GEMs. Can batch-corrected counts of an integrated scRNA-seq data be pooled and normalized in a similar fashion for use with ftINIT?
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Hello, I have a question regarding the application of ftINIT to construct GEMs from integrated scRNA-seq data.
As far as I understand, UMI counts of single-cell bootstraps are pooled and converted to CPM before ftINIT can be used to construct bootstrap-specific GEMs. Can batch-corrected counts of an integrated scRNA-seq data be pooled and normalized in a similar fashion for use with ftINIT?
Thank you in advance.
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