DESCRIPTION

Package: Pmetrics
License: GPL (>= 3)
Title: Pmetrics for Population Modeling and Simulation
Type: Package
Roxygen: list(markdown = TRUE)
Description: Pmetrics is short for pharmacometrics, the discipline of modeling drug kinetics and effects on biologic systems, including disease progression. Models can be used to simulate novel therapeutic dosing regimens and/or populations, informing trial design and dosing strategies. The package supports primarily non-parametric but also parametric pharmacometric modeling and simulation with functions to run and analyze the output from all three components of the Pmetrics software suite for population pharmacometric data analysis: 1) IT2B (Iterative Two-Stage Bayesian) for parametric models; 2) NPAG (Non-parametric Adaptive Grid) for non-paramametric models; 3) Simulator for semi-parametric Monte-Carlo simulations. 
Authors@R: c(
  person("Michael", "Neely", email = "mneely@usc.edu", role = c("aut", "cre")),
  person("Julián", "Otálvaro", email = "juliandavid347@gmail.com", role = "aut"),
  person("Markus", "Hovd", email = "", role = "ctb"),
  person("Walter", "Yamada", email = "", role= "ctb"),
  person("Alan", "Schumitzky", email = "", role = "ctb"),
  person("Rong", "Chen", email = "", role = "ctb"),
  person("Michael", "van Guilder", email = "", role = "ctb"),
  person("David", "Bayard", email = "", role = "ctb"),
  person("Robert", "Leary", email = "", role = "ctb")
    )
Version: 2.1.2
URL: https://lapkb.github.io/Pmetrics/
BugReports: https://github.com/LAPKB/Pmetrics/issues
SystemRequirements: Cargo (>= 1.82) (Rust's package manager), rustc
Depends: 
    R (>= 4.0.0)
Imports:
    bslib,
    crayon,
    doParallel,
    DT,
    dplyr,
    DT,
    ggplot2,
    ggraph,
    jsonlite,
    lifecycle,
    lubridate,
    magrittr,
    openxlsx,
    pander,
    plotly,
    purrr,
    R6,
    readr,
    remotes,
    rlang,
    rmarkdown,
    shiny,
    stats,
    stringr,
    tibble,
    tidygraph,
    tidyr,
    trelliscopejs,
    patchwork,
    mvtnorm,
    utils
Suggests:
    data.table,
    devtools,
    ggpubr,
    htmltools,
    knitr,
    mclust,
    npde,
    pandoc,
    patchwork,
    PmetricsData,
    progress,
    RColorBrewer,
    RcppTOML,
    reticulate,
    testthat,
    trelliscopejs
Remotes: LAPKB/PmetricsData
RoxygenNote: 7.3.2
Encoding: UTF-8
Config/testthat/edition: 3
VignetteBuilder: knitr
Config/rextendr/version: 0.3.1