diff --git a/lib/usdUfe/ufe/StagesSubject.cpp b/lib/usdUfe/ufe/StagesSubject.cpp
index 6d774792f3..0b333ef17b 100644
--- a/lib/usdUfe/ufe/StagesSubject.cpp
+++ b/lib/usdUfe/ufe/StagesSubject.cpp
@@ -528,6 +528,24 @@ void StagesSubject::stageChanged(
             Ufe::SceneItem::Ptr sceneItem = Ufe::Hierarchy::createItem(ufePath);
             if (!sceneItem || InAddOrDeleteOperation::inAddOrDeleteOperation()) {
                 sendObjectDestroyed(ufePath);
+
+                // If we are not in an add or delete operation, and a prim is
+                // removed, we need to trigger a subtree invalidation.  This is
+                // necessary in order to prevent stale items from being kept in
+                // the global selection set.
+                if (!InAddOrDeleteOperation::inAddOrDeleteOperation()) {
+                    auto       parentPath = changedPath.GetParentPath();
+                    const auto parentUfePath = parentPath == SdfPath::AbsoluteRootPath()
+                        ? stagePath(sender)
+                        : stagePath(sender)
+                            + Ufe::PathSegment(
+                                parentPath.GetString(), UsdUfe::getUsdRunTimeId(), '/');
+
+                    auto parentItem = Ufe::Hierarchy::createItem(parentUfePath);
+                    if (parentItem) {
+                        sendSubtreeInvalidate(parentItem);
+                    }
+                }
             } else {
                 sendSubtreeInvalidate(sceneItem);
             }
diff --git a/test/lib/ufe/testSelection.py b/test/lib/ufe/testSelection.py
index 085839d466..2132e068b7 100644
--- a/test/lib/ufe/testSelection.py
+++ b/test/lib/ufe/testSelection.py
@@ -307,7 +307,7 @@ def testMayaSelectAddFirst(self):
         for sel, expected in zip(globalSn, reversedItems):
             self.assertEqual(sel, expected)
 
-    @unittest.skipUnless(mayaUtils.mayaMajorVersion() >= 2023, 'Requires Maya fixes only avaiable in Maya 2023 or greater.')
+    @unittest.skipUnless(mayaUtils.mayaMajorVersion() >= 2023, 'Requires Maya fixes only available in Maya 2023 or greater.')
     def testMayaSelectMuteLayer(self):
         '''Stale selection items must be removed on mute layer.'''
         
@@ -382,6 +382,37 @@ def testMayaSelectMuteLayer(self):
 
         self.assertTrue(sn.empty())
 
+    @unittest.skipUnless(mayaUtils.mayaMajorVersion() >= 2023, 'Requires Maya fixes only available in Maya 2023 or greater.')
+    def testMayaSelectRemoveSelectedPrim(self):
+        '''Stale selection items must be removed when a prim is deleted'''
+        
+        # Create new stage
+        import mayaUsd_createStageWithNewLayer
+        proxyShapePathStr    = mayaUsd_createStageWithNewLayer.createStageWithNewLayer()
+        proxyShapePath       = ufe.PathString.path(proxyShapePathStr)
+        proxyShapeItem       = ufe.Hierarchy.createItem(proxyShapePath)
+        proxyShapeContextOps = ufe.ContextOps.contextOps(proxyShapeItem)
+        stage     = mayaUsd.lib.GetPrim(proxyShapePathStr).GetStage()
+
+        # Create a prim that we will delete
+        proxyShapeContextOps.doOp(['Add New Prim', 'Capsule'])
+
+        capsulePathStr = '%s,/Capsule1' % proxyShapePathStr
+        capsulePath    = ufe.PathString.path(capsulePathStr)
+        capsuleItem    = ufe.Hierarchy.createItem(capsulePath)
+
+        # Select the prim.  When the prim is removed from the stage the prim
+        # should be removed from the global selection
+        sn = ufe.GlobalSelection.get()
+        sn.clear()
+        sn.append(capsuleItem)
+        self.assertTrue(sn.contains(capsulePath))
+
+        stage.RemovePrim("/Capsule1")
+
+        # Should be nothing on the selection list.
+        self.assertTrue(sn.empty())
+
     @unittest.skipUnless(mayaUtils.mayaMajorVersion() >= 2023, 'Requires Maya fixes only available in Maya 2023 or greater.')
     def testMayaSelectSwitchVariant(self):
         '''Stale selection items must be removed on variant switch.'''